CN114602723B - Negative pressure medicine carrying device - Google Patents
Negative pressure medicine carrying device Download PDFInfo
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- CN114602723B CN114602723B CN202210500529.4A CN202210500529A CN114602723B CN 114602723 B CN114602723 B CN 114602723B CN 202210500529 A CN202210500529 A CN 202210500529A CN 114602723 B CN114602723 B CN 114602723B
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- box
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- medicine carrying
- drug
- box body
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C3/00—Apparatus in which the work is brought into contact with a bulk quantity of liquid or other fluent material
- B05C3/02—Apparatus in which the work is brought into contact with a bulk quantity of liquid or other fluent material the work being immersed in the liquid or other fluent material
- B05C3/09—Apparatus in which the work is brought into contact with a bulk quantity of liquid or other fluent material the work being immersed in the liquid or other fluent material for treating separate articles
- B05C3/109—Passing liquids or other fluent materials into or through chambers containing stationary articles
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/56—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor
- A61B17/58—Surgical instruments or methods for treatment of bones or joints; Devices specially adapted therefor for osteosynthesis, e.g. bone plates, screws, setting implements or the like
- A61B17/68—Internal fixation devices, including fasteners and spinal fixators, even if a part thereof projects from the skin
- A61B17/80—Cortical plates, i.e. bone plates; Instruments for holding or positioning cortical plates, or for compressing bones attached to cortical plates
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/0095—Packages or dispensers for prostheses or other implants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/38—Joints for elbows or knees
- A61F2/3859—Femoral components
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/30—Joints
- A61F2/44—Joints for the spine, e.g. vertebrae, spinal discs
- A61F2/4455—Joints for the spine, e.g. vertebrae, spinal discs for the fusion of spinal bodies, e.g. intervertebral fusion of adjacent spinal bodies, e.g. fusion cages
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C11/00—Component parts, details or accessories not specifically provided for in groups B05C1/00 - B05C9/00
- B05C11/10—Storage, supply or control of liquid or other fluent material; Recovery of excess liquid or other fluent material
- B05C11/1002—Means for controlling supply, i.e. flow or pressure, of liquid or other fluent material to the applying apparatus, e.g. valves
- B05C11/1007—Means for controlling supply, i.e. flow or pressure, of liquid or other fluent material to the applying apparatus, e.g. valves responsive to condition of liquid or other fluent material
- B05C11/1013—Means for controlling supply, i.e. flow or pressure, of liquid or other fluent material to the applying apparatus, e.g. valves responsive to condition of liquid or other fluent material responsive to flow or pressure of liquid or other fluent material
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C—APPARATUS FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05C15/00—Enclosures for apparatus; Booths
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
- A61F2250/0068—Means for introducing or releasing pharmaceutical products into the body the pharmaceutical product being in a reservoir
Abstract
The invention provides a negative pressure medicine carrying device, which comprises: a box body; the medicine carrying box is arranged in the box body, a prosthesis with a medicine carrying container is placed in the medicine carrying box in a removable mode, and an opening is formed in the top of the medicine carrying box; the vacuum pump is communicated with the inner cavity of the box body; the medicine pushing device is arranged in the box body and communicated with the inner cavity of the medicine carrying box; the box cover can be covered at the box opening of the box body in an opening and closing way so as to form a closed cavity with the box body. The technical scheme of this application has solved the adoption in the correlation technique effectively and has directly coated or the medicine soaks, soaks mode such as adheres to the medicine on orthopedics implantation apparatus surface for the problem of operation complicacy, and can realize that the prosthesis of aseptic environment carries out the medicine carrying in the art, and realize advantages such as disinfection in the art, the medicine carrying mode of changing the prosthesis in the art.
Description
Technical Field
The invention relates to the field of medical instruments, in particular to a negative pressure medicine carrying device.
Background
In the medical apparatus, the medicine carrying of the apparatus is usually realized by using technical means such as medicine soaking or medicine coating, and in the field of orthopedic apparatus, for example, in the medicine carrying aspect of implanted medical apparatuses such as wound steel plates, spinal fusion cages and artificial joints, no related special medicine coating or medicine carrying device is provided.
Generally, when a clinician needs to use special conditions such as medicine carrying, the medicine is attached to the surface of the orthopedic implant instrument by adopting modes such as direct coating or medicine soaking and infiltration, so that the operation is complex.
Disclosure of Invention
The invention mainly aims to provide a negative pressure medicine carrying device to solve the problem that in the related technology, medicines are attached to the surface of an orthopedic implant instrument in a direct coating mode or a medicine soaking mode, a medicine soaking mode and the like, so that the operation is complex.
In order to achieve the above object, the present application provides a negative pressure drug loading device, comprising: a box body; the medicine carrying box is arranged in the box body, a prosthesis with a medicine carrying container is placed in the medicine carrying box in a removable mode, and an opening is formed in the top of the medicine carrying box; the vacuum pump is communicated with the inner cavity of the box body; the medicine pushing device is arranged in the box body and communicated with the inner cavity of the medicine carrying box; the box cover can be opened and closed and is arranged at the box opening of the box body so as to form a closed cavity with the box body.
Further, negative pressure medicine carrying device still includes the baffle, and the inner chamber of box is separated in order to form first compartment and second compartment to the baffle, and first compartment and second compartment communicate each other, and medicine pusher and medicine carrying box all set up in first compartment, first compartment and medicine carrying box intercommunication, vacuum pump and second compartment intercommunication.
Furthermore, the partition board is horizontally arranged, the first compartment is positioned above the second compartment, the partition board is provided with a plurality of communicating holes which are respectively positioned at two sides of the medicine carrying box, and the medicine pushing device is positioned among the communicating holes.
Further, a sealing structure is arranged between the box cover and the box opening of the box body.
Further, the negative pressure medicine carrying device further comprises a disinfection device arranged in the second compartment.
Furthermore, the sterilizing device comprises a heating pipe, a pressure detection piece and a temperature detection piece are arranged on the outer side wall of the box body, the detection end of the pressure detection piece extends into the box body, and the detection end of the temperature detection piece extends into the box body.
Further, the box and the medicine carrying box are made of transparent materials, and/or the side wall of the box is detachably connected with the vacuum pump through a first plug structure, and the side wall of the medicine carrying box is detachably connected with the medicine pushing device through a second plug structure.
Further, medicine pusher includes the cylinder body and movably sets up in the piston rod of cylinder body, and the cylinder body includes first cavity and second cavity, and the body of rod of piston rod stretches out outside the cylinder body by first cavity, and the second cavity communicates with medicine carrying box and forms the space of filling in the powder.
Further, the piston of the piston rod faces the second chamber, and the surface of the piston rod, which faces the second chamber, is a conical surface.
Further, the second chamber is communicated with the medicine carrying box through a communicating pipeline, and a valve is arranged on the communicating pipeline.
By applying the technical scheme of the invention, the negative pressure medicine carrying device comprises: the box, carry medicine box, vacuum pump, medicine pusher and case lid. The medicine carrying box is arranged in the box body. The prosthesis with the drug carrying container is removably placed in the drug carrying case, and the top of the drug carrying case has an opening. The vacuum pump is communicated with the inner cavity of the box body. The medicine pushing device is arranged in the box body and communicated with the inner cavity of the medicine carrying box. The box cover can be arranged at the box opening of the box body in a covering mode in an opening and closing mode so as to form a closed cavity with the box body. Like this, make the internal negative pressure environment that forms of sealed cavity under the effect of vacuum pump evacuation, medicine pusher can be according to patient's actual clinical user demand in the art, filling medicine type as required, inject the medicine slowly and get into medicine carrying box, and take out to the negative pressure state after in with medicine carrying box through the vacuum pump, the hole of medicine carrying container and false body is filled to the medicine in the medicine carrying box, thereby the false body that has medicine carrying container can carry out medicine carrying fast under sterile environment, need not like adopting direct coating or medicine to soak among the correlation technique, modes such as infiltration adhere to the medicine, and convenient operation. Therefore, the technical scheme of the application can solve the problem that the operation is complex due to the fact that medicines are attached to the surface of the orthopedic implant instrument in the modes of direct coating or medicine soaking, infiltration and the like in the related technology.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this application, are included to provide a further understanding of the invention, and are incorporated in and constitute a part of this specification, illustrate embodiment(s) of the invention and together with the description serve to explain the invention and not to limit the invention. In the drawings:
fig. 1 shows a schematic perspective view of an embodiment of a negative pressure drug-carrying device according to the invention;
fig. 2 shows a schematic top view of the negative pressure drug-carrying device of fig. 1;
fig. 3 shows a schematic cross-sectional view of a drug delivery device of the negative pressure drug-carrying device of fig. 1;
fig. 4 shows a schematic perspective view of a bone plate cooperating with the negative pressure drug-carrying device of fig. 1;
fig. 5 shows a schematic perspective view of a femoral stem matched with the negative pressure drug-carrying device of fig. 1.
Wherein the figures include the following reference numerals:
1. a bone plate; 2. a drug-loaded container; 3. a femoral stem; 10. a box body; 20. carrying a medicine box; 21. a communicating pipeline; 30. a vacuum pump; 40. a drug delivery device; 41. a cylinder body; 42. a piston rod; 50. a box cover; 60. a partition plate; 61. a communicating hole; 70. a sealing structure; 80. a sterilizing device; 81. a pressure detecting member; 82. a temperature detection member; 91. a first switch; 92. a second switch; 93. and a third switch.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. The following description of at least one exemplary embodiment is merely illustrative in nature and is in no way intended to limit the invention, its application, or uses. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
It is noted that the terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of example embodiments according to the present application. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, and it should be understood that when the terms "comprises" and/or "comprising" are used in this specification, they specify the presence of stated features, steps, operations, devices, components, and/or combinations thereof, unless the context clearly indicates otherwise.
The relative arrangement of the components and steps, the numerical expressions and numerical values set forth in these embodiments do not limit the scope of the present invention unless specifically stated otherwise. Meanwhile, it should be understood that the sizes of the respective portions shown in the drawings are not drawn in an actual proportional relationship for the convenience of description. Techniques, methods, and apparatus known to those of ordinary skill in the relevant art may not be discussed in detail but are intended to be part of the specification where appropriate. In all examples shown and discussed herein, any particular value should be construed as merely illustrative, and not limiting. Thus, other examples of the exemplary embodiments may have different values. It should be noted that: like reference numbers and letters refer to like items in the following figures, and thus, once an item is defined in one figure, further discussion thereof is not required in subsequent figures.
As shown in fig. 1 to 5, the negative pressure drug-loading device of the present embodiment includes: the medicine carrying box comprises a box body 10, a medicine carrying box 20, a vacuum pump 30, a medicine pushing device 40 and a box cover 50. The medicine carrying box 20 is disposed in the case 10. The cartridge 20 has a prosthesis with a drug container 2 removably placed therein, and the cartridge 20 has an opening at the top. The vacuum pump 30 communicates with the inner cavity of the housing 10. The medicine pushing device 40 is disposed in the case 10 and communicated with the inner cavity of the medicine carrying box 20. The cover 50 is openably and closably disposed at the opening of the case 10 to form a sealed chamber with the case 10.
By using the technical scheme of the embodiment, a prosthesis with a drug carrying container 2 is placed in the drug carrying case 20 in a removable manner, and the top of the drug carrying case 20 is provided with an opening. The vacuum pump 30 communicates with the inner cavity of the cabinet 10. The medicine pushing device 40 is disposed in the box body 10 and communicated with the inner cavity of the medicine carrying box 20. The cover 50 is openably and closably disposed at the opening of the case 10 to form a sealed chamber with the case 10. Like this, make the internal negative pressure environment that forms of sealed cavity under the effect of vacuum pump 30 evacuation, medicine pusher 40 can be according to patient's in the art actual clinical use demand, filling medicine type as required, slowly inject the medicine and get into medicine carrying box 20, and take out to the negative pressure state back in with medicine carrying box 20 through the vacuum pump, the hole of medicine carrying container 2 and false body is filled to the medicine in the medicine carrying box 20, thereby the false body that has medicine carrying container 2 can carry out the medicine carrying more fast under sterile environment, need not like adopting direct coating or medicine to soak among the correlation technique, infiltration etc. mode adheres to the medicine, and convenient operation. Therefore, the technical scheme of the embodiment can solve the problem of complex operation caused by the fact that medicines are attached to the surface of the orthopedic implant instrument in a direct coating mode or a medicine soaking mode, a medicine infiltrating mode and the like in the related technology. The prosthesis can be a bone plate 1 or a femoral stem 3 or an artificial joint such as a spinal fusion cage. The bone fracture plate 1 and the femoral stem 3 are both made of medical metal and medical polymer material, wherein the medical metal includes but is not limited to titanium and titanium alloy, cobalt alloy, stainless steel, tantalum metal and magnesium alloy, the metal materials are specified in international standards of ISO-5830 series, and the biocompatibility of the metal materials is proved by years of practice of orthopedic implantation application at home and abroad. The medical polymer material includes, but is not limited to, Polycarbonate (PC), silica gel, and polymethyl methacrylate (PMMA). The bone fracture plate 1 can be implanted to the tibia far end of a human body, and the femoral stem can be implanted to the femoral neck bone of the human body and can also be implanted to other fracture positions of four limb joints of the human body.
It should be noted that the drug in this embodiment may be in a liquid state or a solid state. The top of the medicine carrying box 20 may be the top surface of the medicine carrying box 20, or may be the upper half of the medicine carrying box 20. The drug carrying container 2 has a plurality of overflowing holes, so that the drug can be conveniently filled into the cavity of the drug carrying container 2 through the negative pressure drug carrying device. The diameter of the overflowing hole is in the range of 100 micrometers to 800 micrometers; when the medicine carrying container 2 is a medicine carrying ball, the outer diameter of the medicine carrying ball is in the range of 0.5mm to 3mm, and the inner diameter of the medicine carrying ball is in the range of 0.3mm to 2.5 mm; when the medicine carrying container 2 is a medicine carrying tube, the inner diameter of the medicine carrying tube is in the range of 0.05mm to 0.5mm, and the height of the medicine carrying tube is in the range of 1mm to 3 mm. As shown in fig. 1 and 2, the negative pressure drug-carrying device further includes a separator 60. The partition 60 divides the interior of the housing 10 to form a first compartment and a second compartment. The first compartment and the second compartment are communicated with each other, the medicine pushing device 40 and the medicine carrying box 20 are arranged in the first compartment, the first compartment is communicated with the medicine carrying box 20, and the vacuum pump 30 is communicated with the second compartment. The first compartment is convenient for placing the medicine carrying box 20, and the second compartment can form a negative pressure area, so that the air pressure balance in the first compartment and the second compartment can be ensured due to the mutual communication of the first compartment and the second compartment, and the sterile isolation of the medicine carrying box 20 and the medicine pushing device 40 is also facilitated.
In this embodiment, the drug carrying case 20 comprises a bottom wall and a side wall surrounding the edge of the bottom wall, the top of the side wall encloses the opening, the bottom of the side wall is blocked by the bottom wall, and thus a prosthesis with the drug carrying container 2 is conveniently placed in the drug carrying case 20.
As shown in fig. 1 and 2, in order to secure a large space in the horizontal direction in the inner cavity of the cabinet 10, the partition 60 is horizontally disposed, and the first compartment is located above the second compartment. Thus, the medicine carrying boxes 20 with different sizes can be conveniently placed, and prostheses with different specifications can be matched. In order to ensure the balance of the air pressures in the first and second compartments, a plurality of communication holes 61 are formed in the partition 60. The communication holes 61 are respectively arranged at two sides of the medicine carrying box 20, and the medicine pushing device 40 is arranged between the communication holes 61. Like this, when vacuum pump 30 evacuation, medicine carrying box 20 and medicine pusher 40 do not all shelter from a plurality of intercommunicating pores 61, can guarantee the smooth circulation of the gas in first compartment and the second compartment.
As shown in fig. 1 and 2, in order to effectively ensure a sealed cavity between the cover 50 and the housing 10, a sealing structure 70 is provided between the cover 50 and the opening of the housing 10. The sealing structure 70 is preferably a silicone ring.
As shown in fig. 1 and fig. 2, in order to sterilize the sealed cavity at high temperature and high pressure, the negative pressure drug loading device further comprises a sterilizing device 80 disposed in the second compartment, so that when the vacuum pump 30 is not operated, the temperature in the sealed cavity can reach 118 ℃ to 124 ℃, and the pressure reaches 103KPa to 115KPa, so that the prosthesis with the drug loading container 2 can be used for efficient drug loading in a sterile environment.
As shown in fig. 1 and 2, the sterilizing device 80 includes a heating pipe, so that the sterilizing device 80 has a simple structure and low cost. The outer side wall of the case 10 is provided with a pressure detecting member 81 and a temperature detecting member 82. In order to detect the pressure and temperature in the closed cavity in time, the detection end of the pressure detection piece 81 extends into the box body 10, and the detection end of the temperature detection piece 82 extends into the box body 10. The pressure detecting member 81 is preferably a pressure gauge, and the temperature detecting member 82 is preferably a temperature gauge, so that the pressure and temperature values in the sealed cavity can be conveniently read.
As shown in fig. 1 and 2, the negative pressure drug carrying device further includes a first switch 91, a second switch 92, and a third switch 93 disposed on the outer side wall of the case 10. The first switch 91 is connected to the heating tube for controlling the heating tube to be turned on or off. The second switch 92 is connected to the vacuum pump 30 for controlling the on/off of the vacuum pump 30. The third switch 93 is connected to the drug pushing device 40 for controlling the drug pushing device 40 to open and close.
As shown in fig. 1 and 2, the case body 10 and the medicine carrying case 20 are made of transparent materials. The box body 10 and the medicine carrying box 20 made of transparent materials are convenient for observing the medicine infiltration condition of the prosthesis with the medicine carrying container 2. The above-described drug-containing cartridge 20 is a sterile disposable product. In order that the vacuum pump 30 is rapidly communicated with the cabinet 10, the sidewall of the cabinet 10 is detachably connected with the vacuum pump 30 by the first inserting and pulling structure. In order to facilitate quick replacement of the drug carrying box 20 in the box body 10, the side wall of the drug carrying box 20 is detachably connected with the drug pushing device 40 through a second plug structure. The box body 10 and the medicine carrying box 20 are both preferably made of medical PC polycarbonate materials, and the first plugging structure and the second plugging structure are both preferably luer connectors. In the present embodiment, the vacuum pump 30 is connected to the first plug structure through a vacuum line.
Of course, in the embodiment not shown in the figure, the box and the medicine carrying box are both made of transparent materials, or the medicine carrying box is detachably connected in the box through a screw connection structure.
As shown in fig. 1 to 3, the medicine pushing device 40 includes a cylinder 41 and a piston rod 42 movably disposed on the cylinder 41. The cylinder body 41 comprises a first cavity and a second cavity, the rod body of the piston rod 42 extends out of the cylinder body 41 from the first cavity, and the second cavity is communicated with the medicine carrying box 20 and forms a medicine filling space. Thus, the piston of the piston rod 42 sucks the medicine into the medicine filling space by sliding the rod body of the piston rod 42, and the piston of the piston rod 42 slowly pushes the rod body of the piston rod 42 from the first chamber to the second chamber, so that the medicine is slowly pushed into the medicine carrying box 20 by the piston of the piston rod 42. The medicine filling space can be operated in real time according to the actual clinical use requirements of patients in operation, and the medicine types such as anti-infective medicines, bone-promoting medicines, osteoporosis-treating medicines or anti-tumor medicines can be filled according to the needs. The anti-infective drugs include but are not limited to gentamicin, vancomycin, meropenem and voriconazole. Such bone-promoting agents include, but are not limited to, bisphosphonates, paramedians, fluorides, growth hormones. The anti-osteoporosis drugs include, but are not limited to, teriparatide, salmon calcitonin, raloxifene, zoledronic acid. The anti-tumor drugs include but are not limited to alkylating agents and nitrogen mustards, platinum compounds, mitomycin, dihydrofolate reductase inhibitors, actinomycin D, paclitaxel and docetaxel.
As shown in fig. 1 to 3, in order to make the piston of the piston rod 42 slide more smoothly in the cylinder 41, the piston of the piston rod 42 faces the second chamber, and the surface of the piston rod 42 facing the second chamber is a tapered surface.
As shown in fig. 1 to 3, the second chamber is communicated with the medicine carrying box 20 through a communication pipeline 21, and a valve is arranged on the communication pipeline 21. Communicating pipe 21 passes through second plug structure detachably and is connected with the lateral wall of medicine carrying box 20, and second cavity and medicine carrying box 20 intercommunication when opening the valve can hold the medicine in the space of filling in through communicating pipe 21. Placing the prosthesis with the medicine carrying container 2 to be carried in the medicine carrying box 20, and vacuumizing the sealed cavity to 1 × 10 by a vacuum pump 30 -1 KPa, and then be convenient for inject the medicine into medicine carrying box 20 in, the medicine can enter into medicine carrying container 2 and false in vivo, realizes medicine carrying container 2 and falseComplete filling of all voids and cavities in the body. Like this, the inside medicine of medicine container 2 and prosthesis once fills the completion with required medicine through the negative pressure suction technique, can fill different medicines according to actual clinical demand. When the valve is closed, the second chamber is not communicated with the medicine carrying box 20, and the medicine cannot be injected into the medicine carrying box 20, so that the medicine carrying box 20 is convenient to replace. The valve is an electric control valve. The medicine carrying box 20 and the medicine pusher 40 of this embodiment are disposable aseptic products, place the prosthesis that has medicine carrying container 2 through the class of implanting that will be aseptic in medicine carrying box 20, carry out the evacuation back with medicine carrying box 20 through vacuum pump 30, can realize carrying medicine box 20 and having the prosthesis of medicine carrying container 2 and be in under the state of vacuum, this moment through the valve on the automatically controlled release communicating pipe way 21, medicine pusher 40 realizes pushing of liquid medicine, thereby realize that the implanted prosthesis that has medicine carrying container 2 can carry out high-efficient medicine carrying under sterile environment, the placing of realizing anti-infective medicine in the art or the placing that promotes the osseous healing medicine provides the medicine carrying basis. After the prosthesis with the medicine carrying container 2 carries out negative pressure medicine carrying, the outer surface of the prosthesis with the medicine carrying container 2 is coated with biogel to prevent the medicine from overflowing.
In the description of the present invention, it is to be understood that the orientation or positional relationship indicated by the orientation words such as "front, rear, upper, lower, left, right", "lateral, vertical, horizontal" and "top, bottom", etc. are usually based on the orientation or positional relationship shown in the drawings, and are only for convenience of description and simplicity of description, and in the case of not making a reverse description, these orientation words do not indicate and imply that the device or element being referred to must have a specific orientation or be constructed and operated in a specific orientation, and therefore, should not be considered as limiting the scope of the present invention; the terms "inner and outer" refer to the inner and outer relative to the profile of the respective component itself.
Spatially relative terms, such as "above … …," "above … …," "above … …," "above," and the like, may be used herein for ease of description to describe one device or feature's spatial relationship to another device or feature as illustrated in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations of the device in use or operation in addition to the orientation depicted in the figures. For example, if a device in the figures is turned over, devices described as "above" or "on" other devices or configurations would then be oriented "below" or "under" the other devices or configurations. Thus, the exemplary term "above … …" can include both an orientation of "above … …" and "below … …". The device may be otherwise variously oriented (rotated 90 degrees or at other orientations) and the spatially relative descriptors used herein interpreted accordingly.
It should be noted that the terms "first", "second", and the like are used to define the components, and are only used for convenience of distinguishing the corresponding components, and the terms have no special meanings unless otherwise stated, and therefore, the scope of the present invention should not be construed as being limited.
The above description is only a preferred embodiment of the present invention and is not intended to limit the present invention, and various modifications and changes may be made by those skilled in the art. Any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (7)
1. A negative pressure drug-loaded device, comprising:
a case (10);
the medicine carrying box (20) is arranged in the box body (10), a prosthesis with a medicine carrying container (2) is placed in the medicine carrying box (20) in a removable mode, the top of the medicine carrying box (20) is provided with an opening, the medicine carrying container (2) is provided with a plurality of overflowing holes, and medicines are filled into a cavity of the medicine carrying container (2) through a negative-pressure medicine carrying device;
a vacuum pump (30) communicated with the inner cavity of the box body (10);
the medicine pushing device (40) is arranged in the box body (10) and communicated with the inner cavity of the medicine carrying box (20);
the box cover (50) is arranged at the box opening of the box body (10) in a covering mode and can be opened and closed, so that a closed cavity is formed between the box cover and the box body (10);
the negative pressure medicine carrying device further comprises a partition plate (60), the partition plate (60) divides the inner cavity of the box body (10) to form a first compartment and a second compartment, the first compartment and the second compartment are communicated with each other, the medicine pushing device (40) and the medicine carrying box (20) are both arranged in the first compartment, the first compartment is communicated with the medicine carrying box (20), and the vacuum pump (30) is communicated with the second compartment;
the medicine carrying box (20) comprises a bottom wall and a side wall arranged around the edge of the bottom wall in a surrounding mode, the top of the side wall surrounds the opening, and the bottom of the side wall is blocked by the bottom wall; the partition plate (60) is horizontally arranged, the first compartment is positioned above the second compartment, a plurality of communication holes (61) are formed in the partition plate (60), the communication holes (61) are respectively positioned on two sides of the medicine carrying box (20), and the medicine pushing device (40) is positioned between the communication holes (61);
the negative pressure medicine carrying device further comprises a disinfection device (80) arranged in the second compartment, and the disinfection device (80) comprises a heating pipe.
2. The negative pressure drug carrier device according to claim 1, wherein a sealing structure (70) is provided between the case cover (50) and the case mouth of the case body (10).
3. The negative-pressure drug carrying device according to claim 1, wherein a pressure detection piece (81) and a temperature detection piece (82) are arranged on the outer side wall of the box body (10), the detection end of the pressure detection piece (81) extends into the box body (10), and the detection end of the temperature detection piece (82) extends into the box body (10).
4. The negative-pressure drug carrying device according to any one of claims 1 to 3, wherein the box body (10) and the drug carrying box (20) are both made of transparent materials, and/or a side wall of the box body (10) is detachably connected with the vacuum pump (30) through a first plugging structure, and a side wall of the drug carrying box (20) is detachably connected with the drug pushing device (40) through a second plugging structure.
5. The negative pressure drug carrying device according to any one of claims 1 to 3, wherein the drug pushing device (40) comprises a cylinder (41) and a piston rod (42) movably disposed on the cylinder (41), the cylinder (41) comprises a first chamber and a second chamber, a rod body of the piston rod (42) extends out of the cylinder (41) from the first chamber, and the second chamber is communicated with the drug carrying box (20) and forms a drug filling space.
6. The negative pressure drug carrier according to claim 5, characterized in that the piston of the piston rod (42) faces the second chamber, and the surface of the piston rod (42) facing the second chamber is conical.
7. The negative pressure drug loading device according to claim 5, wherein the second chamber is communicated with the drug loading box (20) through a communication pipeline (21), and a valve is arranged on the communication pipeline (21).
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210500529.4A CN114602723B (en) | 2022-05-10 | 2022-05-10 | Negative pressure medicine carrying device |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210500529.4A CN114602723B (en) | 2022-05-10 | 2022-05-10 | Negative pressure medicine carrying device |
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| CN114602723A CN114602723A (en) | 2022-06-10 |
| CN114602723B true CN114602723B (en) | 2022-08-30 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CA2575699C (en) * | 2004-07-30 | 2014-07-08 | Disc-O-Tech Medical Technologies Ltd. | Methods, materials and apparatus for treating bone and other tissue |
| CN101406713B (en) * | 2007-10-12 | 2012-09-19 | 微创医疗器械(上海)有限公司 | Artificial blood vessel bracket and preparation method thereof |
| US8828474B2 (en) * | 2009-09-20 | 2014-09-09 | Medtronic Vascular, Inc. | Apparatus and methods for loading a drug eluting medical device |
| CN102327185A (en) * | 2011-07-14 | 2012-01-25 | 复旦大学 | Method and device for loading substance with porous bracket |
| DE102014113816B3 (en) * | 2014-09-24 | 2015-07-23 | Heraeus Medical Gmbh | Paste application system for storing two starting components, for mixing the starting components into a paste and for applying the paste, and methods for mixing and expelling a paste |
| CN204583546U (en) * | 2015-01-14 | 2015-08-26 | 黄继东 | Vacuum coating equipment |
| CN109248375A (en) * | 2018-11-22 | 2019-01-22 | 柴雪青 | A kind of negative pressure cutaneous penetration instrument and its application method |
| JP7314271B2 (en) * | 2018-11-29 | 2023-07-25 | エシコン・インコーポレイテッド | Silicone Lubricious Coating with Antimicrobial Agent |
| CN111450364A (en) * | 2020-03-31 | 2020-07-28 | 上海新黄河制药有限公司 | Mist control suction device |
| CN213031657U (en) * | 2020-08-11 | 2021-04-23 | 冒进成 | Roller type applicator for dermatology |
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Effective date of registration: 20221107 Address after: 100037, Fu Cheng Road, Beijing, Haidian District, No. 51 Patentee after: Fourth Medical Center, General Hospital of the Chinese PLA Patentee after: BEIJING LIBEIER BIO-ENGINEERING INSTITUTE CO.,LTD. Address before: 102299 No. 12, Chuangxin Road, Changping Science Park, Changping District, Beijing Patentee before: BEIJING LIBEIER BIO-ENGINEERING INSTITUTE CO.,LTD. |