CN114572667A - Material conveying structure and method for radioactive drug production hot chamber - Google Patents

Material conveying structure and method for radioactive drug production hot chamber Download PDF

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Publication number
CN114572667A
CN114572667A CN202210290776.6A CN202210290776A CN114572667A CN 114572667 A CN114572667 A CN 114572667A CN 202210290776 A CN202210290776 A CN 202210290776A CN 114572667 A CN114572667 A CN 114572667A
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CN
China
Prior art keywords
door
shielding
box
box body
lifting mechanism
Prior art date
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Pending
Application number
CN202210290776.6A
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Chinese (zh)
Inventor
文世冬
程佩琪
谢锋
冷翔
吴子健
徐哲峰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Truking Technology Ltd
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Truking Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Truking Technology Ltd filed Critical Truking Technology Ltd
Priority to CN202210290776.6A priority Critical patent/CN114572667A/en
Publication of CN114572667A publication Critical patent/CN114572667A/en
Pending legal-status Critical Current

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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G47/00—Article or material-handling devices associated with conveyors; Methods employing such devices
    • B65G47/74—Feeding, transfer, or discharging devices of particular kinds or types
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G47/00—Article or material-handling devices associated with conveyors; Methods employing such devices
    • B65G47/74—Feeding, transfer, or discharging devices of particular kinds or types
    • B65G47/82—Rotary or reciprocating members for direct action on articles or materials, e.g. pushers, rakes, shovels
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B66—HOISTING; LIFTING; HAULING
    • B66F—HOISTING, LIFTING, HAULING OR PUSHING, NOT OTHERWISE PROVIDED FOR, e.g. DEVICES WHICH APPLY A LIFTING OR PUSHING FORCE DIRECTLY TO THE SURFACE OF A LOAD
    • B66F7/00—Lifting frames, e.g. for lifting vehicles; Platform lifts
    • B66F7/06—Lifting frames, e.g. for lifting vehicles; Platform lifts with platforms supported by levers for vertical movement
    • B66F7/08—Lifting frames, e.g. for lifting vehicles; Platform lifts with platforms supported by levers for vertical movement hydraulically or pneumatically operated
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B66—HOISTING; LIFTING; HAULING
    • B66F—HOISTING, LIFTING, HAULING OR PUSHING, NOT OTHERWISE PROVIDED FOR, e.g. DEVICES WHICH APPLY A LIFTING OR PUSHING FORCE DIRECTLY TO THE SURFACE OF A LOAD
    • B66F7/00—Lifting frames, e.g. for lifting vehicles; Platform lifts
    • B66F7/10—Lifting frames, e.g. for lifting vehicles; Platform lifts with platforms supported directly by jacks
    • B66F7/12—Lifting frames, e.g. for lifting vehicles; Platform lifts with platforms supported directly by jacks by mechanical jacks
    • B66F7/14—Lifting frames, e.g. for lifting vehicles; Platform lifts with platforms supported directly by jacks by mechanical jacks screw operated
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
    • G21F1/00—Shielding characterised by the composition of the materials
    • G21F1/02—Selection of uniform shielding materials
    • G21F1/08—Metals; Alloys; Cermets, i.e. sintered mixtures of ceramics and metals
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
    • G21F5/00—Transportable or portable shielded containers
    • G21F5/06—Details of, or accessories to, the containers
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
    • G21F5/00—Transportable or portable shielded containers
    • G21F5/06—Details of, or accessories to, the containers
    • G21F5/12—Closures for containers; Sealing arrangements
    • G—PHYSICS
    • G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
    • G21F—PROTECTION AGAINST X-RADIATION, GAMMA RADIATION, CORPUSCULAR RADIATION OR PARTICLE BOMBARDMENT; TREATING RADIOACTIVELY CONTAMINATED MATERIAL; DECONTAMINATION ARRANGEMENTS THEREFOR
    • G21F5/00—Transportable or portable shielded containers
    • G21F5/06—Details of, or accessories to, the containers
    • G21F5/14—Devices for handling containers or shipping-casks, e.g. transporting devices loading and unloading, filling of containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65G—TRANSPORT OR STORAGE DEVICES, e.g. CONVEYORS FOR LOADING OR TIPPING, SHOP CONVEYOR SYSTEMS OR PNEUMATIC TUBE CONVEYORS
    • B65G2201/00—Indexing codes relating to handling devices, e.g. conveyors, characterised by the type of product or load being conveyed or handled
    • B65G2201/02—Articles
    • B65G2201/0235—Containers
    • B65G2201/0258—Trays, totes or bins

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  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • High Energy & Nuclear Physics (AREA)
  • Mechanical Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Geology (AREA)
  • Structural Engineering (AREA)
  • Ceramic Engineering (AREA)
  • Metallurgy (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

The invention discloses a material transmission structure of a radioactive drug production hot chamber, which comprises a first shielding box body, wherein the top surface of the first shielding box body is provided with a first box door, one side surface of the first shielding box body is provided with a second box door, a sealing cover is arranged on a shielding container, the sealing cover is detachably connected with the first box door, a production area is provided with a first lifting mechanism for driving the first box door and the sealing cover to lift, and a second lifting mechanism for driving the shielding container to lift is arranged in the first shielding box body. The transmission method comprises the following steps: opening the second box door, putting the shielding container into the first shielding box body, and closing the second box door; the second lifting mechanism drives the shielding container to ascend, the first lifting mechanism drives the first box door and the sealing cover to ascend, and radioactive materials of the shielding container are taken out or radioactive waste materials are put into the shielding container; the first lifting mechanism drives the first box door and the sealing cover to descend, the sealing cover is disconnected with the first box door, and the second lifting mechanism drives the shielding container to descend; and opening the second door to take out the shielding container.

Description

Material conveying structure and method for radioactive drug production hot chamber
Technical Field
The invention relates to food and medicine packaging equipment and a packaging method, in particular to a material conveying structure and a material conveying method of a radioactive medicine production hot chamber.
Background
A radiopharmaceutical production hot chamber is a place for providing shielding, sealing, ventilation and isolation for synthesis, activity detection, subpackaging and the like of radiopharmaceuticals. Because the radioactive medicines have strong radioactivity and certain volatility, after a batch of medicines are produced, the medicines need to be placed for several days or even weeks, and the door can be opened after the radioactivity is reduced to a level acceptable for a human body, so that inconvenience is brought to production. In order to reduce the placing time and improve the production efficiency, the common practice is to transfer production materials to the interior of the hot chamber by adding a feeding and discharging mechanism. Because inside generally being Class 100 or Class 1000 high cleanliness environment of hot chamber and medicine have volatility, destroy the inside environment of hot chamber during in order to prevent the transmission material, prevent revealing of volatile medicine simultaneously, need guarantee the leakproofness of business turn over material drawer, need increase ventilation system simultaneously, to the inside purification of ventilating of drawer, avoid volatile substances to get into in the room, cause the injury to operating personnel.
Patent document CN211699739U discloses a special medicine inlet and outlet structure for radioactive protection hot room, which adopts a mode of arranging sealing doors at two ends of a feeding and discharging drawer to ensure the partition between the hot room and the room (factory building or laboratory, etc.), and simultaneously, the inside of the drawer is ventilated and replaced through inlet and outlet air, so as to reduce the risk of damage to the hot room environment. However, the feeding drawer can only pull back and forth, when materials are taken from the interior of the hot chamber, an operator needs to stretch into the interior of the hot chamber through the operating gloves on the shielding door of the hot chamber and then stretch into the drawer from the interior of the hot chamber to take the materials, and difficulty is brought to material taking; meanwhile, the air supply opening and the air exhaust opening are arranged on the same side, so that a ventilation dead angle exists, and the ventilation and purification effects are poor.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provides a material conveying structure of a radiopharmaceutical production hot chamber, which has a simple structure and is convenient to operate and beneficial to improving the safety.
The invention further provides a transmission method of the material transmission structure of the radiopharmaceutical production hot chamber.
In order to solve the technical problems, the invention adopts the following technical scheme:
the utility model provides a material transmission structure of radioactive drug production hot chamber, hot chamber include the production area and be used for transmitting the radioactive material transmission area of shielding container, and material transmission structure is including the first shielding box body of locating radioactive material transmission area, the first chamber door that is used for intercommunication production area is offered to first shielding box body top surface, and the second chamber door has been seted up to first shielding box body side, be equipped with sealed lid on the shielding container, sealed lid with the connection can be dismantled to first chamber door, the production area is equipped with and is used for driving first chamber door with the first elevating system that sealed lid goes up and down, be equipped with in the first shielding box body and be used for driving the second elevating system that shielding container goes up and down.
As a further improvement of the technical scheme: the sealing cover is provided with a magnetic part, the first box door is provided with an electromagnet, and the first lifting mechanism is connected with the first box door.
As a further improvement of the technical scheme: the first shielding box is internally provided with a supporting seat, the supporting seat is provided with a sliding seat used for transmitting the shielding container, and the sliding seat is connected with the second box door.
As a further improvement of the technical scheme: the shielding container comprises a lead barrel, a lead cover arranged on the lead barrel and a stainless steel barrel arranged in the lead barrel, and the sealing cover is arranged on the stainless steel barrel.
As a further improvement of the technical scheme: the first shielding box body is provided with a first door frame corresponding to the first box door, and the first door frame is matched with the lead barrel in a conical surface mode.
As a further improvement of the above technical solution: the first lifting mechanism comprises a sealing housing and a lifting cylinder arranged in the sealing housing, a piston rod of the lifting cylinder penetrates through the sealing housing, and a sealing ring for holes and a dustproof sealing ring are arranged between the sealing housing and the piston rod of the lifting cylinder.
As a further improvement of the technical scheme: the hot chamber further comprises a non-radioactive material transmission area, the non-radioactive material transmission area and the radioactive material transmission area are arranged oppositely, the non-radioactive material transmission area is provided with a second shielding box body and a transmission box, the top surface of the second shielding box body is provided with a third box door used for communicating the production area, a fourth box door is arranged on one side surface of the second shielding box body, a sliding mechanism used for driving the transmission box to go in and out the fourth box door is arranged in the second shielding box body, and a jacking mechanism used for driving the transmission box to go in and out the third box door is arranged below the sliding mechanism.
As a further improvement of the technical scheme: the sliding mechanism comprises guide rods arranged on two sides of the transmission box, two supporting plates arranged between the two guide rods and a push-pull handle connected with the two guide rods, guide rollers are arranged on the upper side and the lower side of the guide rods on the inner wall of the second shielding box body, one end of the transmission box is arranged on one of the supporting plates, and the other end of the transmission box is arranged on the other supporting plate.
As a further improvement of the technical scheme: the bottom surface of the second shielding box body is provided with a mounting seat, and the jacking mechanism comprises a jacking cylinder arranged on the mounting seat and a tray arranged on a piston rod of the jacking cylinder.
As a further improvement of the technical scheme: the bottom surface of the second shielding box body is connected with an air inlet pipeline, one side surface of the second shielding box body is connected with an air outlet pipeline, and an air inlet fan is arranged on the air inlet pipeline and/or an air outlet fan is arranged on the air outlet pipeline.
A method of transporting a material transport structure of a radiopharmaceutical production hot cell, comprising:
transferring the external radioactive materials to a liquid medicine synthesis area in the hot chamber: radioactive materials are placed into a shielding container, then a second box door is opened, the shielding container is placed into a first shielding box body, then the second box door is closed, a second lifting mechanism drives the shielding container to ascend to the first box door, the first lifting mechanism drives the first box door and a sealing cover to ascend, the radioactive materials in the shielding container are taken out to a liquid medicine synthesis area for synthesis of the radioactive medicines, the first lifting mechanism drives the first box door and the sealing cover to descend, the first shielding box body and the shielding container are both in a closed state, then the connection between the sealing cover and the first box door is disconnected, the second lifting mechanism drives the shielding container to descend, finally the second box door is opened, the shielding container is taken out of the first shielding box body, and then the second box door is closed;
And/or transferring the radioactive waste in the liquid medicine synthesis area in the hot chamber to the outside: opening a second box door, putting the shielding container into a first shielding box body, closing the second box door, driving the shielding container to ascend to the first box door by a second lifting mechanism, driving the first box door and a sealing cover to ascend by the first lifting mechanism, putting radioactive waste in a liquid medicine synthesis area into the shielding container, driving the first box door and the sealing cover to descend by the first lifting mechanism, enabling the first shielding box body and the shielding container to be in a closed state, disconnecting the sealing cover and the first box door, driving the shielding container to descend by the second lifting mechanism, finally opening the second box door, taking the shielding container out of the first shielding box body, and closing the second box door.
Compared with the prior art, the invention has the advantages that: the invention discloses a material transmission structure of a radioactive drug production hot chamber, radioactive materials in a room are firstly put into a shielding container, then a second box door is opened, the shielding container is put into a first shielding box, then the second box door is closed, a second lifting mechanism drives the shielding container to ascend to the position of the first box door, a first lifting mechanism drives a first box door and a sealing cover to ascend, at the moment, the first box door and the shielding container are both in an opened state, the radioactive materials in the shielding container can be taken out to a production area for the synthesis and other operations of the radioactive drugs, or radioactive waste materials in the production area can be put into the shielding container, then the first lifting mechanism drives the first box door and the sealing cover to descend, so that the first box door and the shielding container are both in a closed state, then the connection between the sealing cover and the first box door is disconnected, and the second lifting mechanism can drive the shielding container to descend independently, and finally, the second box door is opened, the shielding container is taken out from the first shielding box body, and then the second box door is closed, so that the structure is simple, the operation is convenient, at least one of the first box door and the second box door is in a closed state in the whole transmission process, the radiation of a production area can be effectively prevented from entering a room through the first shielding box body, the radiation is transmitted linearly, even if a small amount of radiation enters the first shielding box body through the first box door, the radiation is difficult to continue to be transmitted out from the second box door, and the safety of operators is ensured.
According to the transmission method of the material transmission structure of the radioactive drug production hot chamber, disclosed by the invention, at least one of the first box door and the second box door is in the closed state in the whole transmission process, so that radiation or volatile gas in a production area can be effectively prevented from entering a room through the first shielding box body, the radiation is transmitted linearly, even if a small amount of radiation enters the first shielding box body through the first box door, the radiation is difficult to continuously transmit from the second box door, and the safety of operators is ensured.
Drawings
Fig. 1 is a schematic view showing a first usage state of the material transporting structure of the radiopharmaceutical production hot chamber of the present invention.
Fig. 2 is a schematic perspective view of a first shielding box in the present invention.
Fig. 3 is a schematic sectional view of the first shield case of the present invention.
Fig. 4 is a partially enlarged view of fig. 3.
Fig. 5 is a schematic view of the structure of the shield container of the present invention.
Fig. 6 is a schematic perspective view of a second door of the present invention.
Fig. 7 is a schematic structural view of a second use state of the present invention.
Fig. 8 is a perspective view of a second shield case according to the present invention.
Fig. 9 is a schematic cross-sectional view of the transport box of the present invention at the third door.
Fig. 10 is a schematic cross-sectional view of the transport box of the present invention at the fourth door.
Fig. 11 is a perspective view schematically illustrating the sliding mechanism of the present invention.
Fig. 12 is a schematic sectional view of the jacking mechanism in the present invention.
The reference numerals in the figures denote: 1. a first shield case; 11. a first door; 12. a second door; 13. an electromagnet; 14. a supporting seat; 15. a sliding seat; 16. a first door frame; 2. a shielding container; 21. a sealing cover; 22. a magnetic member; 23. a lead barrel; 24. a lead cover; 25. a stainless steel barrel; 3. a first lifting mechanism; 31. sealing the housing; 32. a lifting cylinder; 33. a sealing ring for the hole; 34. a dustproof sealing ring; 4. a hot chamber; 41. a production area; 42. a radioactive material transfer area; 43. a non-radioactive material transfer zone; 5. a second shielding box body; 51. a third box door; 52. a fourth door; 53. a guide roller; 54. a mounting seat; 55. an air inlet pipeline; 56. an air outlet pipeline; 57. an air intake fan; 6. a transmission box; 7. a sliding mechanism; 71. a guide bar; 72. a support plate; 73. a push-pull handle; 8. a jacking mechanism; 81. jacking a cylinder; 82. a tray; 9. and a second lifting mechanism.
Detailed Description
The invention is described in further detail below with reference to the figures and specific examples of the specification.
Referring to fig. 1 to 6, in the material conveying structure of the radioactive drug production hot chamber of the present embodiment, the hot chamber 4 includes a production area 41 and a radioactive material conveying area 42 for conveying the shielding container 2 (for radioactive materials, the radioactive materials need to be placed in the shielding container 2 for conveying to ensure the safety of the operator, and may be barrel-shaped containers, box-shaped containers, and the like), the material conveying structure includes a first shielding box 1 disposed in the radioactive material conveying area 42, a first box door 11 for communicating the production area 41 (that is, the production area 41 is located above the radioactive material conveying area 42) is disposed on a top surface of the first shielding box 1, a second box door 12 is disposed on a side surface of the first shielding box 1, a sealing cover 21 is disposed on the shielding container 2, the sealing cover 21 is detachably connected with the first box door 11, the production area 41 is provided with a first lifting mechanism 3 for driving the first box door 11 and the sealing cover 21 to lift up and down, a second lifting mechanism 9 for driving the shielding container 2 to lift is arranged in the first shielding box body 1.
According to the material transmission structure of the radioactive drug production hot chamber, radioactive materials in a room (such as a production factory or a laboratory) are firstly put into the shielding container 2, then the second door 12 is opened, the shielding container 2 is put into the first shielding box body 1, then the second door 12 is closed, the second lifting mechanism 9 drives the shielding container 2 to ascend to the first door 11, the first lifting mechanism 3 drives the first door 11 and the sealing cover 21 to ascend, at the moment, the first door 11 and the shielding container 2 are both in an open state, the radioactive materials in the shielding container 2 can be taken out to the production area 41 for the synthesis of the radioactive drugs and other operations, or radioactive waste materials in the production area 41 can be put into the shielding container 2, and then the first lifting mechanism 3 drives the first door 11 and the sealing cover 21 to descend, so that the first door 11 and the shielding container 2 are both in a closed state, then the connection between the sealing cover 21 and the first box door 11 is disconnected, the second lifting mechanism 9 can drive the shielding container 2 to independently descend, finally the second box door 12 is opened, the shielding container 2 is taken out from the first shielding box body 1, and then the second box door 12 is closed, the structure is simple, the operation is convenient, at least one of the first box door 11 and the second box door 12 is in a closed state in the whole transmission process, the radiation of the production area 41 can be effectively prevented from entering a room through the first shielding box body 1, the radiation is transmitted linearly, even if a small amount of radiation enters the first shielding box body 1 through the first box door 11, the radiation is difficult to continuously transmit from the second box door 12, and the safety of operators is ensured.
Further, in the present embodiment, the sealing cover 21 is provided with a magnetic member 22 (e.g., a magnetic block, a magnetic plate, etc.), the first door 11 is provided with an electromagnet 13, and the first lifting mechanism 3 is connected to the first door 11. When the second lifting mechanism 9 drives the shielding container 2 to ascend to the first door 11, the electromagnet 13 is electrified to generate attraction to attract the magnetic member 22, so that the connection between the sealing cover 21 and the first door 11 is realized, at the moment, the first lifting mechanism 3 can drive the first door 11 to ascend to separate from the first shielding box body 1, and meanwhile, the sealing cover 21 is separated from the shielding container 2; when the first lifting mechanism 3 drives the first box door 11 and the sealing cover 21 to descend until the first box door 11 seals the first shielding box body 1, the electromagnet 13 is powered off, no acting force exists between the magnetic piece 22 and the electromagnet 13, namely, the connection between the sealing cover 21 and the first box door 11 is disconnected, the sealing cover 21 descends under the action of self gravity to seal the shielding container 2, and then the second lifting mechanism 9 can drive the shielding container 2 to descend independently, so that the structure is simple and the use is convenient.
Further, in the embodiment, a supporting seat 14 is disposed in the first shielding box 1, a sliding seat 15 for transporting the shielding container 2 is disposed on the supporting seat 14, and the sliding seat 15 is connected to the second door 12. When the second door 12 is opened, the sliding seat 15 can be synchronously pulled out from the first shielding box body 1, correspondingly, when the second door 12 is closed, the sliding seat 15 can be synchronously pushed into the first shielding box body 1, the supporting seat 14 can support the sliding seat 15, and the sliding seat are in sliding fit (for example, a sliding rail is matched with a sliding block, a pulley is matched with the sliding rail, and the like), the friction resistance is small, the shielding container 2 can be placed on the sliding seat 15, and the shielding container 2 can conveniently and laborsavingly enter and exit the first shielding box body 1.
Further, in the present embodiment, the shielding container 2 includes a lead barrel 23, a lead cover 24 disposed on the lead barrel 23, and a stainless steel barrel 25 disposed in the lead barrel 23, and the sealing cover 21 is disposed on the stainless steel barrel 25. Lead barrel 23 and lead cover 24 cooperate and form the confined cavity, can realize the shielding of radioactive material, and stainless steel bucket 25 cooperates with sealed lid 21 and forms the confined cavity, can prevent the leakage of volatile substances, simple structure, reliable. Wherein the lead cover 24 needs to be removed before placing the shield container 2 on the slide base 15.
Further, in this embodiment, a first door frame 16 is disposed at a position corresponding to the first shielding box 1 and the first door 11, and the first door frame 16 and the lead barrel 23 are in conical surface fit. When the second lifting mechanism 9 drives the lead barrel 23 to ascend and butt with the first door frame 16, a better sealing structure can be formed between the lead barrel 23 and the first door frame 16 through conical surface matching, after the sealing cover 21 and the first door 11 ascend, the leakage of radioactivity and volatile substances in the production area 41 and the lead barrel 23 can be prevented, the gas replacement operation in the first shielding box body 1 is not needed, and the structure is simple and reliable.
Further, in the present embodiment, the first lifting mechanism 3 includes a sealing cover 31 and a lifting cylinder 32 disposed in the sealing cover 31, a piston rod of the lifting cylinder 32 penetrates through the sealing cover 31, and a sealing ring 33 for a hole and a dust-proof sealing ring 34 are disposed between the sealing cover 31 and the piston rod of the lifting cylinder 32. The lifting cylinder 32 is arranged in the sealed housing 31, and the hole sealing ring 33 and the dustproof sealing ring 34 are arranged between the sealed housing 31 and the piston rod of the lifting cylinder 32, so that the pollution caused by the lifting cylinder 32 is prevented, and the high cleanliness of the production area 41 is maintained. Wherein, the second lifting mechanism 9 can also adopt a cylinder or an electric cylinder, a screw-nut pair and the like to drive the lead barrel 23 to lift.
Referring to fig. 7 to 12, in this embodiment, the hot chamber 4 further includes a non-radioactive material transmission area 43, the non-radioactive material transmission area 43 and the radioactive material transmission area 42 are arranged oppositely (in fig. 1, the non-radioactive material transmission area 43 and the radioactive material transmission area are respectively arranged on the left and right sides to ensure that the radioactive material transmission process and the non-radioactive material transmission process can be performed independently and avoid mutual influence), the non-radioactive material transmission area 43 is provided with a second shielding box 5 and a transmission box 6 (for the non-radioactive materials, radiation shielding is not required to be considered), the top surface of the second shielding box 5 is provided with a third box door 51 for communicating the production area 41, one side surface of the second shielding box 5 is provided with a fourth box door 52, a sliding mechanism 7 for driving the transmission box 6 to enter and exit the fourth box door 52 is arranged in the second shielding box 5, and a jacking mechanism 8 for driving the transmission box 6 to enter and exit the third box door 51 is arranged below the sliding mechanism 7.
The non-radioactive materials in the room are firstly put into the transmission box 6, then the fourth door 52 is opened, the transmission box 6 is put on the sliding mechanism 7, then the sliding mechanism 7 is pushed into the second shielding box body 5, finally the third door 51 is closed, after the transmission box 6 is put in place, the jacking mechanism 8 drives the transport box 6 to ascend to the third door 51, and at this time, the third door 51 is opened, so that the non-radioactive materials in the transport box 6 can be taken out to the production area 41, or the non-radioactive waste in the production area 41 can be put into the transmission box 6, then the third door 51 is closed, the transmission box 6 is driven to descend by the jacking mechanism 8, finally the fourth door 52 is opened, the sliding mechanism 7 is drawn out from the second shielding box body 5, the transport box 6 can be taken out, and then the fourth door 52 is closed, so that the structure is simple, the operation is convenient, and the tightness of the non-radioactive material transport area 43 can be ensured.
Further, in this embodiment, the sliding mechanism 7 includes guide rods 71 disposed at two sides of the transmission box 6, two support plates 72 disposed between the two guide rods 71 (that is, the two guide rods 71 and the two support plates 72 form a rectangular structure), and a push-pull handle 73 connected to the two guide rods 71, guide rollers 53 are disposed on the upper and lower sides of the guide rods 71 on the inner wall of the second shielding box 5, one end of the transmission box 6 is disposed on one of the support plates 72, and the other end of the transmission box 6 is disposed on the other support plate 72. The guide rollers 53 on the upper side and the lower side of the guide rod 71 can provide support and limiting guide effects for the guide rod 71, friction resistance between the guide rod 71 and the transmission box is small, the sliding mechanism 7 and the transmission box 6 can be conveniently pulled out of or pushed into the second shielding box 5 manually, and the structure is simple and reliable.
Further, in this embodiment, the mounting seat 54 is disposed on the bottom surface of the second shielding box 5, and the jacking mechanism 8 includes a jacking cylinder 81 disposed on the mounting seat 54 and a tray 82 disposed on a piston rod of the jacking cylinder 81. When the transmission box 6 moves to the position above the tray 82, the piston rod stretches and retracts to drive the tray 82 and the transmission box 6 to ascend and descend, and the structure is simple and reliable. Of course, in other embodiments, the jacking mechanism 8 may also adopt an electric cylinder, a screw-nut pair, or the like to jack the transmission box 6.
Further, in this embodiment, the bottom surface of the second shielding box 5 is connected with an air inlet duct 55, one side surface of the second shielding box 5 is connected with an air outlet duct 56, the air inlet duct 55 is provided with an air inlet fan 57, clean air is input into the second shielding box 5 through the air inlet duct 55, and meanwhile volatile air is discharged from the air outlet duct 56, so that the air replacement of the second shielding box 5 can be realized, the high cleanliness inside the hot chamber 4 is ensured, meanwhile, the volatile air is prevented from leaking into the room, and the air inlet duct 55 and the air outlet duct 56 are respectively located on the bottom surface and the side surface, which helps to eliminate ventilation dead corners and ensures that the replacement effect is simple and reliable in structure. Of course, in other embodiments, an air outlet fan (not shown) may be disposed on the air outlet pipe 56, or both the air inlet fan 57 and the air outlet fan may be disposed.
As a preferred embodiment, the first shielding box body 1 is provided with inflatable sealing rings at positions corresponding to the first box door 11 and the second box door 12, and when the first box door 11 and the second box door 12 are in a closed state, the inflatable sealing rings are inflated to ensure the sealing performance; when the first box door 11 and the second box door 12 need to be opened, the inflatable sealing rings exhaust; similarly, the second shielding box 5 is also provided with inflatable sealing rings at the positions corresponding to the third box door 51 and the fourth box door 52; an O-shaped sealing ring can be arranged on the bottom surfaces of the mounting seat 54 and the second shielding box body 5, a hole sealing ring 33 and a dustproof sealing ring 34 can be arranged between a piston rod of the jacking cylinder 81 and the mounting seat 54, and the jacking cylinder 81 is prevented from damaging the cleanliness of the second shielding box body 5.
The transmission method of the material transmission structure of the radiopharmaceutical production hot chamber comprises the following steps: the method comprises the following steps:
the external radioactive material is transferred to the liquid medicine synthesizing area in the hot chamber 4: radioactive materials are put into the shielding container 2, then the second door 12 is opened, the shielding container 2 is put into the first shielding box body 1, then the second door 12 is closed, the second lifting mechanism 9 drives the shielding container 2 to rise to the first door 11, the first lifting mechanism 3 drives the first door 11 and the sealing cover 21 to rise, the radioactive materials in the shielding container 2 are taken out to a liquid medicine synthesis area for synthesis of the radioactive materials, the first lifting mechanism 3 drives the first door 11 and the sealing cover 21 to fall, so that the first shielding box body 1 and the shielding container 2 are both in a closed state, then the connection between the sealing cover 21 and the first door 11 is disconnected, the second lifting mechanism 9 drives the shielding container 2 to fall, finally the second door 12 is opened, the shielding container 2 is taken out of the first shielding box body 1, and then the second door 12 is closed;
and/or the radioactive waste of the liquid medicine synthesis zone inside the hot chamber 4 is transferred to the outside: the second door 12 is opened, the shielding container 2 is placed into the first shielding box body 1, the second door 12 is closed again, the second lifting mechanism 9 drives the shielding container 2 to ascend to the first door 11, the first lifting mechanism 3 drives the first door 11 and the sealing cover 21 to ascend, radioactive waste in the liquid medicine synthesis area is placed into the shielding container 2, the first lifting mechanism 3 drives the first door 11 and the sealing cover 21 to descend, the first shielding box body 1 and the shielding container 2 are both in a closed state, then connection between the sealing cover 21 and the first door 11 is disconnected, the second lifting mechanism 9 drives the shielding container 2 to descend, finally, the second door 12 is opened, the shielding container 2 is taken out of the first shielding box body 1, and the second door 12 is closed again.
According to the transmission method, at least one of the first box door 11 and the second box door 12 is in a closed state in the whole transmission process, radiation or volatile gas in the production area 41 can be effectively prevented from entering a room through the first shielding box body 1, the radiation is transmitted linearly, even if a small amount of radiation enters the first shielding box body 1 through the first box door 11, the radiation is difficult to continuously transmit from the second box door 12, and the safety of operators is guaranteed.
Although the present invention has been described with reference to the preferred embodiments, it is not intended to be limited thereto. Those skilled in the art can make many possible variations and modifications to the disclosed solution, or modify equivalent embodiments using the teachings disclosed above, without departing from the scope of the solution. Therefore, any simple modification, equivalent change and modification made to the above embodiments according to the technical essence of the present invention shall fall within the protection scope of the technical solution of the present invention, unless the technical essence of the present invention departs from the content of the technical solution of the present invention.

Claims (10)

1. A material transfer structure of a radiopharmaceutical production hot cell, the hot cell (4) comprising a production zone (41) and a radioactive material transfer zone (42) for transferring shielded containers (2), characterized in that: the material transmission structure comprises a first shielding box body (1) arranged in a radioactive material transmission area (42), a first box door (11) used for communicating a production area (41) is arranged on the top surface of the first shielding box body (1), a second box door (12) is arranged on one side surface of the first shielding box body (1), a sealing cover (21) is arranged on a shielding container (2), the sealing cover (21) is detachably connected with the first box door (11), the production area (41) is provided with a first lifting mechanism (3) used for driving the first box door (11) and the sealing cover (21) to lift, and a second lifting mechanism (9) used for driving the shielding container (2) to lift is arranged in the first shielding box body (1).
2. The material transport structure of a radiopharmaceutical production hot cell of claim 1, wherein: the refrigerator door is characterized in that a magnetic part (22) is arranged on the sealing cover (21), an electromagnet (13) is arranged on the first refrigerator door (11), and the first lifting mechanism (3) is connected with the first refrigerator door (11).
3. The material transport structure of a radiopharmaceutical production hot cell of claim 1, wherein: a supporting seat (14) is arranged in the first shielding box body (1), a sliding seat (15) used for transmitting the shielding container (2) is arranged on the supporting seat (14), and the sliding seat (15) is connected with the second box door (12).
4. The material transport structure of a radiopharmaceutical production hot cell of claim 1, wherein: the shielding container (2) comprises a lead barrel (23), a lead cover (24) arranged on the lead barrel (23) and a stainless steel barrel (25) arranged in the lead barrel (23), and the sealing cover (21) is arranged on the stainless steel barrel (25).
5. The material transport structure for a radiopharmaceutical production hot chamber of claim 3, wherein: a first door frame (16) is arranged at the position, corresponding to the first box door (11), of the first shielding box body (1), and the first door frame (16) is matched with the lead barrel (23) in a conical surface mode.
6. The material transport structure of a radiopharmaceutical production hot cell of claim 1, wherein: first elevating system (3) are including sealed housing (31) and locate lift cylinder (32) in sealed housing (31), the piston rod of lift cylinder (32) runs through sealed housing (31), sealed housing (31) with be equipped with between the piston rod of lift cylinder (32) hole with sealing washer (33) and dustproof sealing washer (34).
7. The material transport structure of a radiopharmaceutical production hot chamber of any one of claims 1 to 6, wherein: the hot chamber (4) further comprises a non-radioactive material transmission area (43), the non-radioactive material transmission area (43) and the radioactive material transmission area (42) are arranged oppositely, the non-radioactive material transmission area (43) is provided with a second shielding box body (5) and a transmission box (6), the top surface of the second shielding box body (5) is provided with a third box door (51) used for communicating the production area (41), a side surface of the second shielding box body (5) is provided with a fourth box door (52), the second shielding box body (5) is internally provided with a sliding mechanism (7) used for driving the transmission box (6) to enter and exit the fourth box door (52), and the lower part of the sliding mechanism (7) is provided with a jacking mechanism (8) used for driving the transmission box (6) to enter and exit the third box door (51).
8. The material transport structure of a radiopharmaceutical production hot cell of claim 7, which is characterized in that: the sliding mechanism (7) comprises guide rods (71) arranged on two sides of the transmission box (6), two supporting plates (72) arranged between the two guide rods (71) and a push-pull handle (73) connected with the two guide rods (71), guide rollers (53) are arranged on the upper side and the lower side of the guide rods (71) on the inner wall of the second shielding box body (5), one end of the transmission box (6) is arranged on one of the supporting plates (72), and the other end of the transmission box (6) is arranged on the other supporting plate (72).
9. The material transport structure of a radiopharmaceutical production hot cell of claim 7, which is characterized in that: the air inlet pipeline (55) is connected to the bottom surface of the second shielding box body (5), an air outlet pipeline (56) is connected to one side surface of the second shielding box body (5), an air inlet fan (57) is arranged on the air inlet pipeline (55) and/or an air outlet fan is arranged on the air outlet pipeline (56).
10. A method of transporting a material transporting structure of a radiopharmaceutical production hot chamber defined in any one of claims 1 to 9, which comprises: the method comprises the following steps:
the external radioactive materials are transmitted to a liquid medicine synthesis area in the hot chamber (4): radioactive materials are put into the shielding container (2), then the second door (12) is opened, the shielding container (2) is put into the first shielding box body (1), then the second door (12) is closed, the second lifting mechanism (9) drives the shielding container (2) to rise to the position of the first door (11), the first lifting mechanism (3) drives the first door (11) and the sealing cover (21) to rise, the radioactive materials in the shielding container (2) are taken out to a liquid medicine synthesis area for synthesis of the radioactive materials, the first lifting mechanism (3) drives the first door (11) and the sealing cover (21) to fall, the first shielding box body (1) and the shielding container (2) are both in a closed state, then the connection between the sealing cover (21) and the first door (11) is disconnected, the second lifting mechanism (9) drives the shielding container (2) to fall, and finally the second door (12) is opened, taking the shielding container (2) out of the first shielding box body (1), and closing the second box door (12);
And/or the radioactive waste of the liquid medicine synthesis zone inside the hot chamber (4) is transferred to the outside: opening a second door (12), putting the shielding container (2) into the first shielding box body (1), closing the second door (12), driving the shielding container (2) to ascend to the first door (11) by a second lifting mechanism (9), driving the first door (11) and a sealing cover (21) to ascend by a first lifting mechanism (3), putting radioactive waste in a liquid medicine synthesis area into the shielding container (2), driving the first door (11) and the sealing cover (21) to descend by the first lifting mechanism (3), and enabling the first shielding box body (1) and the shielding container (2) to be in a closed state, then the connection between the sealing cover (21) and the first box door (11) is disconnected, the second lifting mechanism (9) drives the shielding container (2) to descend, finally the second box door (12) is opened, the shielding container (2) is taken out from the first shielding box body (1), and then the second box door (12) is closed.
CN202210290776.6A 2022-03-23 2022-03-23 Material conveying structure and method for radioactive drug production hot chamber Pending CN114572667A (en)

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Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN203217960U (en) * 2013-05-06 2013-09-25 余巧生 Radionuclide split-charging protective cabinet
KR20150137791A (en) * 2014-05-30 2015-12-09 성균관대학교산학협력단 Apparatus for synthesis of radioactive compound
KR101610548B1 (en) * 2014-12-04 2016-04-08 (주)유니테코 Isolation type clean bench with radiopharmaceuticals generator lifting platform
CN209030865U (en) * 2018-11-07 2019-06-28 临沂市畜牧站 Bee farm with cooling device
CN210297025U (en) * 2019-09-27 2020-04-10 国网河南省电力公司博爱县供电公司 Prepackage type box-type substation
CN211699739U (en) * 2020-01-10 2020-10-16 华克医疗科技（北京）股份公司 Special medicine structure of business turn over of radioactivity protection hotroom
CN217024313U (en) * 2022-03-23 2022-07-22 楚天科技股份有限公司 Material conveying structure of radioactive drug production hot chamber

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN203217960U (en) * 2013-05-06 2013-09-25 余巧生 Radionuclide split-charging protective cabinet
KR20150137791A (en) * 2014-05-30 2015-12-09 성균관대학교산학협력단 Apparatus for synthesis of radioactive compound
KR101610548B1 (en) * 2014-12-04 2016-04-08 (주)유니테코 Isolation type clean bench with radiopharmaceuticals generator lifting platform
CN209030865U (en) * 2018-11-07 2019-06-28 临沂市畜牧站 Bee farm with cooling device
CN210297025U (en) * 2019-09-27 2020-04-10 国网河南省电力公司博爱县供电公司 Prepackage type box-type substation
CN211699739U (en) * 2020-01-10 2020-10-16 华克医疗科技（北京）股份公司 Special medicine structure of business turn over of radioactivity protection hotroom
CN217024313U (en) * 2022-03-23 2022-07-22 楚天科技股份有限公司 Material conveying structure of radioactive drug production hot chamber

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