CN114554955B - 用于检测醇的分析物传感器和感测方法 - Google Patents

用于检测醇的分析物传感器和感测方法 Download PDF

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Publication number
CN114554955B
CN114554955B CN202080070792.3A CN202080070792A CN114554955B CN 114554955 B CN114554955 B CN 114554955B CN 202080070792 A CN202080070792 A CN 202080070792A CN 114554955 B CN114554955 B CN 114554955B
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Prior art keywords
alcohol
sensor
active region
analyte sensor
working electrode
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Chinese (zh)
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CN114554955A (zh
Inventor
B·J·费尔德曼
T·欧阳
A·H·瓦利
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Abbott Diabetes Care Inc
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Abbott Diabetes Care Inc
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/98—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving alcohol, e.g. ethanol in breath
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/14546—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue for measuring analytes not otherwise provided for, e.g. ions, cytochromes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1473—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter
    • A61B5/14735—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means invasive, e.g. introduced into the body by a catheter comprising an immobilised reagent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/145—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue
    • A61B5/1468—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means
    • A61B5/1486—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase
    • A61B5/14865—Measuring characteristics of blood in vivo, e.g. gas concentration or pH-value ; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid or cerebral tissue using chemical or electrochemical methods, e.g. by polarographic means using enzyme electrodes, e.g. with immobilised oxidase invasive, e.g. introduced into the body by a catheter or needle or using implanted sensors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/26—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating electrochemical variables; by using electrolysis or electrophoresis
    • G01N27/28—Electrolytic cell components
    • G01N27/30—Electrodes, e.g. test electrodes; Half-cells
    • G01N27/327—Biochemical electrodes, e.g. electrical or mechanical details for in vitro measurements

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biophysics (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Medical Informatics (AREA)
  • Optics & Photonics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Organic Chemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Electrochemistry (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
CN202080070792.3A 2019-08-30 2020-08-28 用于检测醇的分析物传感器和感测方法 Active CN114554955B (zh)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202411588968.0A CN119454020A (zh) 2019-08-30 2020-08-28 用于检测醇的分析物传感器和感测方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962894306P 2019-08-30 2019-08-30
US62/894,306 2019-08-30
PCT/US2020/048497 WO2021041875A1 (en) 2019-08-30 2020-08-28 Analyte sensors and sensing methods for the detection of alcohol

Related Child Applications (1)

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CN202411588968.0A Division CN119454020A (zh) 2019-08-30 2020-08-28 用于检测醇的分析物传感器和感测方法

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CN114554955A CN114554955A (zh) 2022-05-27
CN114554955B true CN114554955B (zh) 2024-12-03

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CN202411588968.0A Pending CN119454020A (zh) 2019-08-30 2020-08-28 用于检测醇的分析物传感器和感测方法

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US (2) US11918355B2 (cg-RX-API-DMAC7.html)
EP (1) EP4021301A1 (cg-RX-API-DMAC7.html)
JP (3) JP7473632B2 (cg-RX-API-DMAC7.html)
CN (2) CN114554955B (cg-RX-API-DMAC7.html)
AU (2) AU2020337996C1 (cg-RX-API-DMAC7.html)
CA (1) CA3148534A1 (cg-RX-API-DMAC7.html)
WO (1) WO2021041875A1 (cg-RX-API-DMAC7.html)

Families Citing this family (7)

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CN114554955B (zh) * 2019-08-30 2024-12-03 美国雅培糖尿病护理公司 用于检测醇的分析物传感器和感测方法
US20220304599A1 (en) * 2019-08-31 2022-09-29 PercuSense, Inc. Analyte sensor
KR102819228B1 (ko) * 2022-04-08 2025-06-11 주식회사 아이코어바이오 금속 촉매 기반의 알코올 센서 및 그를 포함하는 웨어러블 장치
WO2024038358A1 (en) * 2022-08-15 2024-02-22 Know Labs, Inc. Systems and methods for analyte-based access controls
US12318203B2 (en) 2022-08-15 2025-06-03 Know Labs, Inc. Vehicle interface systems and methods for analyte-based access control
US12033451B2 (en) 2022-08-15 2024-07-09 Know Labs, Inc. Systems and methods for analyte-based access controls
WO2025128711A1 (en) * 2023-12-12 2025-06-19 Abbott Diabetes Care Inc. Alcohol sensor membrane

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US4713327A (en) * 1985-05-01 1987-12-15 Eastman Kodak Company Determination of total creatine kinase or an isoenzyme with a multilayer analytical element
US5320725A (en) * 1989-08-02 1994-06-14 E. Heller & Company Electrode and method for the detection of hydrogen peroxide
JPH03125955A (ja) * 1989-10-12 1991-05-29 Nippondenso Co Ltd バイオガスセンサ
US6736957B1 (en) 1997-10-16 2004-05-18 Abbott Laboratories Biosensor electrode mediators for regeneration of cofactors and process for using
US6134461A (en) 1998-03-04 2000-10-17 E. Heller & Company Electrochemical analyte
US6605201B1 (en) 1999-11-15 2003-08-12 Therasense, Inc. Transition metal complexes with bidentate ligand having an imidazole ring and sensor constructed therewith
US7501053B2 (en) 2002-10-23 2009-03-10 Abbott Laboratories Biosensor having improved hematocrit and oxygen biases
US20190357827A1 (en) * 2003-08-01 2019-11-28 Dexcom, Inc. Analyte sensor
US8983568B2 (en) 2008-09-30 2015-03-17 Abbott Diabetes Care Inc. Analyte sensors comprising leveling agents
EP2292751A1 (de) * 2009-08-20 2011-03-09 Roche Diagnostics GmbH Stabilisierung von Enzymen mit stabilen Coenzymen
JP5795584B2 (ja) 2009-08-31 2015-10-14 アボット ダイアベティス ケア インコーポレイテッドAbbott Diabetes Care Inc. 医療用装置
US20160313358A1 (en) * 2015-04-23 2016-10-27 Ted Titmus Diagnostic test strips for detection of pre-specified blood alcohol levels
EP4325222A3 (en) * 2016-03-04 2024-05-01 Abbott Diabetes Care Inc. Nad(p)-dependent responsive enzymes, electrodes and sensors, and methods for making and using the same
CN110268067A (zh) * 2016-08-16 2019-09-20 伊美格生物科学公司 用于产生立体异构纯的氨基环丙烷的组合物和方法
WO2018039572A1 (en) * 2016-08-26 2018-03-01 Hitachi Chemical Co. America, Ltd. Enzymatic biosensors, hydrogel compositions therefor, and methods for their production
JP2019529935A (ja) * 2016-10-05 2019-10-17 エフ ホフマン−ラ ロッシュ アクチェン ゲゼルシャフト 多検体診断用試験エレメントのための検出試薬および電極配置、ならびにそれらを使用する方法
ES2969074T3 (es) * 2017-02-17 2024-05-16 Hoffmann La Roche Electrodo de monitorización continua de analito con enzima reticulada
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Publication number Publication date
US20210059587A1 (en) 2021-03-04
AU2020337996C1 (en) 2024-05-02
JP2022545714A (ja) 2022-10-28
US20240225498A1 (en) 2024-07-11
WO2021041875A1 (en) 2021-03-04
JP7823103B2 (ja) 2026-03-03
AU2020337996A1 (en) 2022-03-10
JP7473632B2 (ja) 2024-04-23
CN114554955A (zh) 2022-05-27
AU2020337996B2 (en) 2023-11-09
AU2024200759A1 (en) 2024-02-29
CA3148534A1 (en) 2021-03-04
US11918355B2 (en) 2024-03-05
EP4021301A1 (en) 2022-07-06
CN119454020A (zh) 2025-02-18
AU2024200759B2 (en) 2026-06-04
JP2026069637A (ja) 2026-04-23
JP2024083550A (ja) 2024-06-21

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Inventor after: B.J. Feldman

Inventor after: T. Ouyang

Inventor after: A.H. Wali

Inventor before: B.J. Feldman

Inventor before: T. Ouyang

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