CN114544991A - Sample analysis device and control method thereof - Google Patents

Sample analysis device and control method thereof Download PDF

Info

Publication number
CN114544991A
CN114544991A CN202011338297.4A CN202011338297A CN114544991A CN 114544991 A CN114544991 A CN 114544991A CN 202011338297 A CN202011338297 A CN 202011338297A CN 114544991 A CN114544991 A CN 114544991A
Authority
CN
China
Prior art keywords
reagent
sample
disk
screen
reagent disk
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202011338297.4A
Other languages
Chinese (zh)
Inventor
臧誉淇
邱凯宁
何赟
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shenzhen Mindray Bio Medical Electronics Co Ltd
Original Assignee
Shenzhen Mindray Bio Medical Electronics Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shenzhen Mindray Bio Medical Electronics Co Ltd filed Critical Shenzhen Mindray Bio Medical Electronics Co Ltd
Priority to CN202011338297.4A priority Critical patent/CN114544991A/en
Publication of CN114544991A publication Critical patent/CN114544991A/en
Pending legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N35/00732Identification of carriers, materials or components in automatic analysers
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/0092Scheduling
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/025Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations having a carousel or turntable for reaction cells or cuvettes
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1009Characterised by arrangements for controlling the aspiration or dispense of liquids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/00584Control arrangements for automatic analysers
    • G01N35/00722Communications; Identification
    • G01N2035/00891Displaying information to the operator
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/02Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
    • G01N35/04Details of the conveyor system
    • G01N2035/0401Sample carriers, cuvettes or reaction vessels
    • G01N2035/0403Sample carriers with closing or sealing means

Landscapes

  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)

Abstract

A touch reagent screen is introduced, a diagram of a reagent disk is displayed on the reagent screen and divided into a plurality of partitions, and the number of the partitions can be set, so that a specific area on the reagent disk can be more finely rotated to an operation area, particularly a more optimal sub-area in the operation area, and the experience of an operator with low height is improved.

Description

Sample analysis device and control method thereof
Technical Field
The present invention relates to a sample analyzer and a control method thereof.
Background
A sample analyzer, such as a biochemical analyzer, an immunological analyzer, a cell analyzer, and the like, is a device for analyzing and measuring a sample, and generally measures a chemical component, a concentration, and the like in a sample by adding a reagent to the sample and then reacting the sample with the reagent in a predetermined manner.
The sample analyzer will consume reagents continuously during the testing process, so operators will usually replenish reagent consumables before the test starts every day; and as the test progresses, the online loading of consumables such as reagents and the like may need to be continuously carried out.
In order to carry as much reagent as possible, reagent carrying parts of sample analyzers, such as reagent trays, are currently made larger, which makes it difficult for operators with low height to reach reagent sites in certain corners of the operating area due to the larger reagent tray structure when the operator stands in front of the sample analyzer to rotate the reagent tray and replace the reagent.
Disclosure of Invention
In view of the above problems, a sample analyzer and a control method thereof are provided, which will be described in detail below.
According to a first aspect, an embodiment provides a sample analysis device comprising:
the sample introduction part is used for dispatching a sample;
the sample dispensing component is used for sucking the sample on the sample feeding component and discharging the sample into the reaction cup;
a reagent tray having a plurality of reagent sites, wherein the reagent sites are for carrying reagents; the reagent tray can rotate and drive the reagent carried by the reagent tray to rotate;
a reagent dispensing member for sucking a reagent and discharging the reagent into a reaction cup;
a reaction part for incubating a mixed solution formed by a sample and a reagent in the reaction cup;
a measurement unit for measuring the incubated mixture;
a processor and a touch-sensitive reagent screen, wherein:
the reagent screen is used for displaying a reagent disk state interface, the reagent disk state interface at least displays a shape representation diagram of the reagent disk, and the shape representation diagram of the reagent disk is divided into a plurality of subareas; in response to a partition setting instruction, the processor controls setting the schematic of the reagent disk to a corresponding number of partitions;
in response to the clicking operation on any one of the partitions, the processor controls the clicked partition to rotate to a preset operation area in the reagent disk corresponding to the actual area.
According to a second aspect, an embodiment provides a method of controlling a sample analysis apparatus including a reagent disk and a touch-sensitive reagent screen, the method comprising:
controlling the reagent screen to display a reagent disk state interface, wherein at least a shape display diagram of the reagent disk is displayed on the reagent disk state interface, and the shape display diagram of the reagent disk is divided into a plurality of subareas;
in response to the clicking operation on any one of the partitions, the processor controls the clicked partition to rotate to a preset operation area in the reagent disk corresponding to the actual area.
According to a third aspect, an embodiment provides a computer-readable storage medium comprising a program executable by a processor to implement a method as described in any of the embodiments herein
According to the sample analysis device, the control method thereof and the computer readable storage medium of the embodiment, by introducing the touch type reagent screen, the shape graph of the reagent disk displayed on the reagent screen is divided into a plurality of partitions, and the number of the partitions can be set, so that a specific area on the reagent disk can be more finely rotated to an operation area, especially a more optimal sub-area in the operation area, and the experience of an operator with low height is improved.
Drawings
FIG. 1 is a schematic diagram of a sample analysis system according to an embodiment;
FIG. 2 is a schematic diagram of a sample analysis system according to another embodiment;
FIG. 3 is a schematic diagram of a preprocessing module according to an embodiment;
FIG. 4 is a schematic diagram of an exemplary aftertreatment module;
FIG. 5 is a schematic diagram of a sample analysis system according to yet another embodiment;
FIG. 6(a) is a schematic view of a sample analyzer according to an embodiment;
FIG. 6(b) is a schematic structural view of a sample analyzer according to another embodiment;
FIGS. 7(a) and 7(b) are schematic views of the reagent disk with the reagent disk lid opened and the reagent disk lid closed;
FIG. 8(a) is a schematic structural view of a reagent disk according to an embodiment;
FIG. 8(b) is a schematic structural view of a reagent disk according to another embodiment;
FIG. 9 is a schematic structural view of a reagent disk according to still another embodiment;
FIG. 10 is a schematic diagram of an overview interface of an embodiment;
FIG. 11 is a schematic diagram of an overview interface of an embodiment;
FIG. 12 is a schematic view of a reagent disk status interface according to one embodiment;
FIG. 13 is a schematic view of a reagent disk status interface of another embodiment;
FIG. 14 is a schematic view of a reagent disk status interface of yet another embodiment;
FIG. 15 is a schematic view showing 4 partitions of a reagent disk in one embodiment;
FIG. 16 is a schematic diagram showing 8 partitions of a reagent disk in one embodiment;
FIG. 17(a) is an interface displayed on a computer display screen according to an embodiment; FIG. 17(b) is a schematic view of a reagent disk status interface according to an embodiment; FIG. 17(c) is a schematic diagram of the reagent disk state interface after the "Erlenmeyer flask" button is clicked in one embodiment; FIG. 17(d) is a schematic diagram of an embodiment of a reagent disk status interface with a checklist being exhaled; FIG. 17(e) is an example of a schematic diagram in which the reagent disk status interface of one embodiment includes two reagent disks; FIG. 17(f) is an example of a reagent disk status interface of an embodiment being locked; FIG. 17(g) is a schematic diagram of a reagent disk state interface showing a reagent disk being in a scanning state after the reagent disk is covered with a reagent disk cover according to an embodiment; FIG. 17(h) is a schematic diagram of a clicked-to-counter consumable and rack consumable interface in a reagent disk state interface according to an embodiment; FIG. 17(i) is an example of an embodiment in which the reagent screen jumps back to the overview interface after the reagent disk has been scanned;
FIG. 18(a) is an example of a reagent screen that lights up and displays an overview interface if there is insufficient reagent or consumable during a test; FIG. 18(b) is a diagram illustrating an overview interface, in accordance with an embodiment; FIG. 18(c) is a diagram illustrating an embodiment of a priority view window key being clicked on the overview interface; FIG. 18(d) is a diagram showing an example of a countdown displayed by clicking a reagent pause button on a reagent screen; fig. 18(e) and 18(f) show examples in which the computer display and the reagent screen are linked to prompt the operator to open the reagent disk cover, respectively; FIG. 18(g) is an example of the reagent screen displaying a scan countdown after closing the reagent disk cover;
FIG. 19 is a schematic illustration of a reagent disk failure at the reagent disk state interface;
FIG. 20 is a schematic view of a reagent disk in a scanning state at the interface of the disk state;
FIG. 21 is a partial top view of a sample analysis device according to one embodiment;
FIG. 22 is a flow chart of a sample analysis method according to another embodiment;
FIG. 23 is a flow chart of a sample analysis method according to yet another embodiment;
FIG. 24 is a flowchart of a sample analysis method according to still another embodiment;
FIG. 25 is a flow chart of a sample analysis method of yet another embodiment;
FIG. 26 is a flowchart of a sample analysis method according to yet another embodiment;
fig. 27 is a flowchart of a control method of a sample analysis apparatus according to still another embodiment;
fig. 28 is a flowchart of a control method of a sample analysis apparatus of yet another embodiment;
fig. 29 is a flowchart of a sample analysis method according to still another embodiment.
Detailed Description
The present invention will be described in further detail with reference to the following detailed description and accompanying drawings. Wherein like elements in different embodiments are numbered with like associated elements. In the following description, numerous details are set forth in order to provide a better understanding of the present application. However, those skilled in the art will readily recognize that some of the features may be omitted or replaced with other elements, materials, methods in different instances. In some instances, certain operations related to the present application have not been shown or described in detail in order to avoid obscuring the core of the present application from excessive description, and it is not necessary for those skilled in the art to describe these operations in detail, so that they may be fully understood from the description in the specification and the general knowledge in the art.
Furthermore, the features, operations, or characteristics described in the specification may be combined in any suitable manner to form various embodiments. Also, the various steps or actions in the method descriptions may be transposed or transposed in order, as will be apparent to one of ordinary skill in the art. Thus, the various sequences in the specification and drawings are for the purpose of describing certain embodiments only and are not intended to imply a required sequence unless otherwise indicated where such sequence must be followed.
The numbering of the components as such, e.g., "first", "second", etc., is used herein only to distinguish the objects as described, and does not have any sequential or technical meaning. The term "connected" and "coupled" when used in this application, unless otherwise indicated, includes both direct and indirect connections (couplings).
The numbering of the components as such, e.g., "first", "second", etc., is used herein only to distinguish the objects as described, and does not have any sequential or technical meaning. The term "connected" and "coupled" when used in this application, unless otherwise indicated, includes both direct and indirect connections (couplings).
The sample analysis device may be connected to a computer display screen, which is typically located on a desk, through which an operating teacher may view some of the states of the sample analysis device. For example, for a reagent change scenario, a typical reagent change procedure is such that: an operation teacher checks and counts the residual test quantity of the on-machine reagent on a software interface of a computer screen, records the reagent items and the reagent positions and the like needing to be unloaded, and records the types of the reagents needing to be supplemented and the quantity of the reagents needing to be supplemented by mental calculation; after consumables such as reagent and the like are taken out, the consumables are moved to a reagent bearing part such as a reagent disk to rotate to find a reagent position to be unloaded; in order to find out the position of a target reagent, a reagent disk needs to be rotated manually in a coordinated manner by hands and eyes, and the reagent disk is difficult to rotate in place at one time and cannot be conveniently found out to be replaced; in the batch replacement process, if the reagent position is found to be insufficient, the computer is required to return to the front of the computer, check the reagent with small residual quantity, record the reagent position again, return to the side of the reagent plate and repeatedly load and unload the reagent again. Can traditional reagent load especially reagent load in batches the flow very loaded down with trivial details, the operation mr changes reagent inefficiency in batches, has seriously influenced the time that the test of inspection administrative or technical offices begins.
The above is a single-machine test scenario, and a system formed by cascading a plurality of sample analyzers is similar, except that the cascaded sample analyzers are all connected to a common computer display screen, and the operating teacher can check the states of various sample analyzers through the common computer display screen.
As can be seen from the above description, before changing the reagent, if the operator needs to check the reagent information, the operator needs to operate the computer software to search many interfaces in front of the computer display screen, and then hand-copy and record the required information. When an operator changes the reagent before the reagent tray, the operator needs to return to the front of a computer display screen to operate and record when finding that the lost information is lost; therefore, during reagent replacement, the operator often frequently walks back and forth between the sample analyzer and the computer display.
A more specific example of a traditional reagent batch load is the following: the operator needs to replenish the sample analyzer with reagents and consumables before each day of testing, taking the replenishment of reagents as an example:
the operator first operates the software on a computer display screen to view and manually record which reagents need to be replenished, a process which typically takes 15 to 20 minutes;
then the operator goes to a reagent warehouse to take back the corresponding reagent, records the bottle opening date on the reagent container, and opens the reagent tray cover;
then the serial number of the reagent position of the reagent to be replaced on the reagent tray is checked on a computer display screen or paper recorded by an operator, then the corresponding reagent position is rotated to a target position by rotating the reagent tray through a physical button beside the reagent tray, an empty bottle or a reagent bottle with insufficient allowance is taken out, then a new reagent bottle is put on the corresponding reagent position on the reagent tray, the reagent bottle with insufficient allowance can be covered for standby, and finally the reagent tray is covered, and the process takes about 40 to 60 minutes.
The whole process has many pain points, for example, the test items are more, so an operator needs to turn over and read a plurality of pages on a computer display screen to check the reagent allowance of each item, and mentally calculate the number of bottles to be supplemented; when the reagent is loaded specifically, checking a reagent supplement list recorded by the user, checking the reagent position of the reagent disk to be loaded with the reagent, and loading the reagent; when the rotating disc is rotated, the reagent disc is rotated through the hardware button, the position of the reagent disc cover which is exposed needs to be looked at continuously, and the reagent position corresponding to the reagent disc cannot be rotated to the target position at one time easily; in addition, in the case of a plurality of reagent disks, the reagent disk on the side away from the user operation of the sample analyzer is not easy to operate and observe.
A more specific example of a conventional on-line loading of reagents is the following: the sample analysis device can display alarm information through a computer display screen when the reagent is insufficient; then, an operator can check which items have insufficient reagents and which reagents need to be supplemented through a computer display screen, and then go to a reagent warehouse to retrieve the corresponding reagents; and after the reagent tray is taken back, a reagent pause command is sent through a computer display screen, a long period of time is waited, after the reagent tray finishes the stop of the current scheduled project, the cover of the reagent tray is opened, then the empty bottle is taken out, a new reagent bottle is placed, the cover of the reagent tray is closed, and the test is recovered by clicking through the computer display screen.
Pain points exist in the whole process, for example, an instrument only has an interface for alarming, and the instrument is not easy to be invented by an operator in time; the operator needs to wait long enough (e.g. 5-50 minutes) before the instrument to open the lid for loading; after loading is completed, the user can return to the test state by clicking the recovery test instrument.
The present application attempts to address one or more of the above pain spots to facilitate the exchange and replenishment of sample analysis device reagents by a departmental teacher or the like, improving work efficiency.
Referring to fig. 1 and fig. 2, an embodiment of the present invention provides a sample analysis system, which may include a sample introduction part 10, a pre-processing module 20, a plurality of sample analysis main bodies 30 and a post-processing module 40, and the sample analysis system may further include a computer display screen 50, or the sample analysis system is externally connected to a computer display screen 50; . The modules of the sample analysis system are described in detail below.
The sample introduction component 10 is used for receiving and dispatching a sample. The sample introduction part 10 in the sample analysis system is generally an area where a user puts a sample, and when the system is in operation, the sample introduction part 10 can perform automatic code scanning, sample sorting and the like on the sample put therein. For example, the sample introduction part 10 is used to supply a sample rack carrying samples to be tested, so as to dispatch the samples to be introduced to a preset position, such as a sample suction position. In some embodiments, the Sample introduction part 10 may be implemented by a Sample Delivery Module (SDM) and a track. In the sample analysis system, the sample introduction part 10 serves to receive and distribute a sample to each sample analysis body 30 for testing.
The pre-treatment module 20 can receive the sample from the sample introduction part 10 and complete the pre-treatment of the sample. In one embodiment, referring to fig. 3, the pre-processing module 20 may include one or more of a centrifuge module 21, a serum detection module 22, a decapping module 23, and a dispensing module 24. The centrifuge modules 21 are used for centrifuging the sample to be centrifuged, and the number of the centrifuge modules 21 may be one or more. The serum test module 22 is used to determine whether the serum amount of the sample is sufficient and/or whether the serum quality of the sample is acceptable, so as to determine whether the centrifuged sample can be used for subsequent determination. The decapping module 23 is used for decapping the centrifuged sample — as will be understood, capping, coating, decapping, and decapping the sample herein, it refers to capping, coating, decapping, and decapping the sample tube containing the sample; generally, the sample needs to be uncapped after centrifugation for subsequent dispensing or pipetting by the dispensing module 24 or the sample analyzer 30. The dispensing module 24 is used for dispensing a sample, for example, dividing one sample into a plurality of samples to be sent to the corresponding sample analyzer 30 for measurement. The preprocessing module 20 generally has a preprocessing flow: the centrifugal module 21 receives the sample dispatched by the sample introduction part 10 and centrifuges the sample; the serum detection module 22 detects serum of the centrifuged sample, and judges whether the serum can be used for subsequent measurement, and if the serum is insufficient in amount or unqualified in quality, the serum cannot be used for subsequent measurement; if the detection is passed, the sample is dispatched to the decapping module 23, the decapping module 23 removes the cap of the sample, if the dispensing module 24 is available, the dispensing module 24 sorts the decapped sample, then the sorted sample is dispatched to the corresponding sample analysis device 30 for measurement, and if the dispensing module 24 is not available, the sample is dispatched from the decapping module 23 to the corresponding sample analysis device 30 for measurement.
As described above, the preprocessing module 20 is not necessary, and for a sample analysis system without the preprocessing module 20, the sample put in the sample feeding part 10 by the user is a sample that has been preprocessed, and can be directly dispatched to the corresponding sample analysis device 30 through the track 50 to be measured.
The sample analysis subject 30 is used to perform a test on the sample. For example, the test is performed on a sample that has been centrifuged and decapped by the pre-treatment module 20. To improve efficiency and test throughput, a sample analysis system will typically have a plurality of sample analysis subjects 30, and these sample analysis subjects 30 may be the same kind of analysis module, i.e., the analysis module for determining the same item, or different kinds of analysis modules, i.e., the analysis module for determining different items, which may be configured according to the needs of the user and the department. In some embodiments, the sample analysis body 30 may include a housing 1, components for measurement such as a sample dispensing component 32, a reagent carrying component 33, a reagent dispensing component 34, a reaction component 35, a measurement component 36, and the like, and the sample analysis body 30 may further include a processor 37 — fig. 6(a) and 6(b) are two examples below. The various analyzing main bodies 30 are provided with a status information screen 38 fixed to the housing 1 thereof to facilitate the user to view some status of the sample analyzing main body 30, for example, status information on reagents and/or consumables. The sample analysis subject 30 and its status information screen 38 are described in more detail below.
The post-processing module 40 is used to complete post-processing of the sample. In one embodiment, referring to fig. 4, the post-treatment module 40 includes one or more of a capping/filming module 41, a refrigerated storage module 42, and a decapping/decapping module 43. A membrane/capping module 41 for coating or capping the sample; the refrigerated storage module 42 is used to store samples; the stripping/decapping module 43 is used to strip or decap the sample. One typical post-processing flow for post-processing module 40 is: after the sample analysis subject 30 is aspirated, the sample is dispatched to the membrane/capping module 41, and the membrane/capping module 41 performs membrane or capping on the sample after the measurement is completed, and then dispatches the sample to the cold storage module 42 for storage. If the sample requires retesting, the sample is dispatched from the refrigerated storage module 42, stripped or decapped in a stripping/decapping module 43, and then dispatched to the sample analysis body 30 for testing.
The post-processing module 40 is not necessary, and for a sample analysis system without the post-processing module 40, the determined sample can be dispatched to a centralized recycling area, and then the user can recycle the sample in the recycling area for some subsequent processing such as saving or discarding.
The computer display screen 50 is connected with the various analysis main bodies 30 in a communication mode, and an operation teacher can check some states of various analysis devices through the computer display screen 50.
Referring to fig. 5, as an example of the pipeline system, each module further includes a module buffer, and the track of the sample injection component 10 also has a track buffer, and the whole track may be a circular track. It should be noted that there are only one module of many types shown in the drawings, but those skilled in the art will understand that the number is not limited herein, for example, there may be more than one centrifuge module 21, more than one sample analysis main body 30, and the like.
In the sample analysis system, some information of the corresponding sample analysis subject 30 can be conveniently viewed and/or the corresponding sample analysis subject 30 can be controlled by the status information screen 38 provided for each kind of the sample analysis subject 30; the information of all the sample analysis subjects 30 can be viewed in a unified manner and/or all the sample analysis subjects 30 can be controlled via the computer screen 50.
In some embodiments, the processors 37 of the various analysis subjects 30 are capable of executing corresponding instructions in response to manipulation of the computer display screen 50; the various analysis subjects 30 are also capable of executing corresponding instructions in response to the operation of their status information screens 38. In other words, the operator can give commands to various analyzing subjects 30 by operating the computer screen 50, and the operator can give commands to the corresponding sample analyzing subjects 30 through the status information screen 38.
In some embodiments, the processors 37 of the various analysis subjects 30 may acquire status information of the respective sample analysis subjects 30 and generate first type display data and second type display data, and transmit the first type display data to the computer display screen 50 for display and the second type display data to the respective status information screens 38 for display. Therefore, the user can view the status information of various sample analysis subjects 30 through the computer display screen 50, and can also view the status information of the sample analysis subject 30 before walking to the sample analysis subject 30 through the status information screen 38 on the housing of the sample analysis subject 30. In some implementations, the first type of display data includes more information than the second type of data. Specifically, the first type of display data may include at least sample information, reagent status information, consumable status information, calibration information, quality control information, test result information, and maintenance information; the second type of display data may include status information of the reagent, and further, the second type of display data may further include consumable information.
In a specific communication connection mode, the processor 37 of the sample analysis main body 30 can be connected with the state information screen 38 on the shell 1 of the sample analysis main body 30 in a wired mode for data transmission; the processor 37 of the sample analysis subject 30 may be connected by wire to the computer display screen 50 for data transfer.
In a particular mechanical configuration and positional arrangement, a status information screen 38 on the housing 1 of the sample analysis body 30 may be provided in the vicinity of the reagent carrying part 33 of the sample analysis body 30. The computer display 50 may be disposed on the sample injection component 10, for example, the sample injection component 10 may have a housing, and generally, the housing can form a "load bearing platform" -for example, the upward side of the sample injection component 10; therefore, the computer display 50 can be disposed or placed on the housing of the sample introduction part 10 facing upward, and then wired to the processors 37 of the various analysis main bodies 30 by cables, or the computer display 50 can be disposed on the housing of the sample introduction part 10 by means of a robot arm or a bracket.
As will be appreciated by those skilled in the art, for sample analysis systems, typically each sample analysis subject has a processor therein, such as the processor 37 mentioned herein; in other examples, the sample analysis system may also have an additional processor for processing some of the sample analysis system's operations, controlling the computer display 50, etc.; alternatively, in some examples, the computer display screen 50 may be configured and have a processor; in some examples, the status information screen 38 may be configured and have a processor. The various analysis agents 30 in the sample analysis system may also be used offline or detached for separate use, which is a stand-alone scenario.
The sample analyzer will be explained below.
Referring to fig. 6(a) and 6(b), some embodiments disclose a sample analysis apparatus, which may include a sample introduction part 10 and a sample analysis body 30, wherein the sample analysis body 30 includes a housing 1 and measurement parts, such as the sample introduction part 10, a sample introduction part 32, a reagent carrying part 33, a reagent introduction part 34, a reaction part 35, a measurement part 36, and the like; the sample analysis subject 30 also includes a processor 37. In some embodiments, the sample analysis device may further include a computer display screen 50; or the sample analysis device is externally connected with a computer display screen 50. The sample analysis device may also include a status information screen 38. This will be explained in detail below.
The sample introduction component 10 is used to schedule samples as described above. For example, the sample introduction part 10 is used to supply a sample rack carrying samples to be tested, so as to dispatch the samples to be introduced to a preset position, such as a sample suction position.
The sample dispensing component 32 is used for sucking the sample on the sample injection component 10 and discharging or injecting the sample into the reaction cup. In some embodiments, the sample dispensing component 32 may include a sample needle that is driven by a two-dimensional or three-dimensional drive mechanism to move in two-dimensional or three-dimensional directions. In some embodiments, the sample needle may be one or more. In one embodiment, the whole operation flow of the sample dispensing component 32 to complete one sample adding or dispensing is as follows: moving to a sample sucking position to suck a sample, then moving to a corresponding cleaning position to clean the outer wall, then moving to a sample adding position to discharge the sucked sample to a reaction cup positioned at the sample adding position, and finally moving to the corresponding cleaning position to clean the inner wall and the outer wall, for example, cleaning a sample dispensing component 32.
The reagent holding member 33 has a plurality of reagent sites for holding reagents. In some embodiments, the reagent carrying part 33 is capable of providing a cooling or the like function to the carried reagent, for example maintaining a temperature between 2 and 16 degrees celsius, thereby ensuring the activity of the reagent. In particular, the reagent carrying part 33 serves to maintain its internal temperature within the range required by the instructions for use of the reagent. To ensure the cooling effect, the reagent carrying part 33 may be a closed structure, for example, the reagent carrying part 33 may be provided with a lid that can be opened and closed to keep warm. The reagent holding member 33 may have a reagent presence/absence detector for detecting whether or not a reagent container is held at the reagent site.
In some embodiments, the reagent carrying part 33 may be a disk-like structure or a linear structure. The reagent holding member 33 having a disk structure is not taken as an example, and the reagent holding member 33 in this case is not called a reagent disk 33 for convenience of explanation. Reagent dish 33 is discoid structure setting, can rotate and drive its reagent that bears and rotate. By the rotation of the reagent disk 33, the reagent can be transferred to the reagent aspirating position for the reagent dispensing unit 34 to aspirate. The reagent disk 33 may have a reagent disk cover 33c that can be opened and closed, and when the reagent disk cover 33c is opened, a user can put or take out a reagent into or from the reagent disk 33. Referring to fig. 7(a) and 7(b), the reagent disk 33 is shown with the reagent disk cover opened and the reagent disk cover closed.
In some specific examples, the reagent disk 33 may include at least one rotatable reagent track 33a, the reagent track 33a includes a plurality of reagent sites 33b for carrying reagents, and the reagent track 33a rotates to move reagent containers on the reagent sites 33b thereof — for example, fig. 8(a) and 8(b) are two examples. In some embodiments, the reagent disk 33 includes multiple reagent tracks 33a, each reagent track 33a being capable of independent rotation. Fig. 8(a) shows an example in which the reagent disk 33 has one turn of the reagent track 33a, and fig. 8(b) shows an example in which the reagent disk 33 has two turns of the reagent track 33a that can rotate independently. The reagent track 33a can rotate and drive the reagent container carried by the reagent track to transfer, so that the reagent container is rotated to a reagent sucking position for the reagent dispensing component 34 to suck the reagent. The reagent tray 33 will be further described with reference to the drawings.
Referring to fig. 8(a), in some embodiments, the reagent tray 33 includes a circle of reagent tracks 33a, reagent sites 33b of which can be used for placing reagent cups 91, each reagent cup 91 includes one or more cavities for containing reagents required for the project test, and one reagent is placed in one cavity; the reagent disk 33 includes a corresponding drive assembly for driving the rotation of the disk 33a, and the drive assembly drives the rotation of the disk 33a to rotate the cavity of the reagent cup 91 containing the reagent required by the project to the corresponding reagent sucking position. In one example, the reagent cups 91 each include at least a first cavity 91a for carrying a first reagent and a second cavity 91b for carrying a second reagent, e.g., the reagent cup 91 includes at least a first cavity 91a for carrying a mixed reagent (not referred to as R1) and a second cavity 91b for carrying a trigger reagent (not referred to as R2); the reagent disk 33 comprises a first reagent absorption position and a second reagent absorption position different from the first reagent absorption position, and the reagent disk 33a is driven to rotate so as to drive the reagent cup 91 to rotate, so that the first cavity 91a of the reagent cup 91 is rotated to the first reagent absorption position; 33a are driven to rotate so as to drive the reagent cup 91 to rotate, so as to rotate the second cavity 91b to the second reagent sucking position. It is understood that the first and second blotting sites are within the scope of the blotting sites herein.
Referring to FIG. 8(b), in some embodiments, the reagent disk 33 includes two independently rotatable rings 33 a-such as the inner ring 33a and the outer ring 33a of the figure. A reagent station 33b of the outer ring 33a for carrying a first reagent container; the reagent site 33b of the outer ring 33a can be used to carry a second reagent container. The reagent disk 33 comprises a corresponding driving component for driving the outer ring 33a to rotate, and the driving component drives the outer ring 33a to rotate and drive the first reagent container to rotate so as to rotate the first reagent container to the first reagent sucking position; the reagent disk 33 further comprises a corresponding drive assembly for driving the inner ring 33a to rotate, and the drive assembly drives the inner ring 33a to rotate and drive the second reagent container to rotate so as to rotate the second reagent container to the second reagent sucking position. It is understood that the first reagent container and the second reagent container herein are within the scope of the reagent container herein.
While two configurations of the reagent disk 33 have been described above, for example, fig. 7(a) shows an example of placing the reagent cup 91, fig. 7(b) shows an example of implementing the reagent disk 33 by a plurality of tracks capable of rotating independently, it will be understood by those skilled in the art that the reagent disk 33 may be implemented by a plurality of tracks capable of rotating independently, and at least one track or each track may have reagent sites 33b for placing the reagent cup 91, for example, fig. 9 shows an example of placing the reagent cup 91 on the inner circle 33a and the reagent site 33b on the outer circle 33 a. By putting all kinds of reagents required for one test item into the same reagent union cup 91, the management of the reagents can be facilitated. Of course, in other embodiments, the consumables in the tray such as the syringe and the diluent may be placed on the inner ring 33a, and the main reagent for testing, such as the mixed reagent and the trigger reagent mentioned above, may be placed on the outer ring 33 a.
The reagent disk 33 is a single disk, and is detachably provided outside the reaction part 35. In other embodiments, there may be more than one reagent disk 33, for example, there may be two reagent disks 33. In some examples where there are two reagent trays 33, one reagent tray 33 may be used to exclusively carry mixed reagent R1 and the other reagent tray 33 may be used to exclusively carry trigger reagent R2.
The above are some of the descriptions of the reagent disk 33. The reagent disk 33 may rotate and dispense the corresponding reagent required for the test item to the corresponding reagent sucking position of the reagent dispensing unit 34 by rotating during the working cycle, for example, a first reagent is dispensed to a first reagent sucking position, and a second reagent is dispensed to a second reagent sucking position.
The reagent dispensing unit 34 is used to aspirate and dispense a reagent into a reaction cuvette located at a reagent addition site. In one embodiment, the reagent dispensing component 34 includes one or more reagent needles. In one embodiment, the whole operation flow of the reagent dispensing unit 34 for completing one reagent adding or dispensing is as follows: moving to a reagent sucking position to suck the reagent, then moving to a corresponding cleaning position to clean the outer wall, then moving to a reagent adding position to discharge the sucked reagent to a reaction cup positioned at the reagent adding position, and finally moving to the corresponding cleaning position to clean the inner wall and the outer wall. In one embodiment, when the reagent needle is set to continuously suck a plurality of reagents and then discharge the reagents together, the reagent needle is controlled to continuously perform a plurality of reagent sucking operations to suck a required plurality of reagents; wherein in the process of sucking the required multiple reagents, after finishing one reagent sucking operation and before starting the next reagent sucking operation, the outer wall of the reagent needle is cleaned.
It will be appreciated by those skilled in the art that in order to prevent cross-contamination during testing, the sample analysis apparatus will typically have corresponding cleaning components for cleaning the sample needle, reagent needle, etc., which may be implemented using conventional structures and will not be described further herein.
The reaction unit 35 is used to incubate a mixed solution of a sample and a reagent in the reaction cup. In some embodiments, the reaction part 35 is disposed in a disc-shaped structure, the reaction part 35 has a plurality of placing positions for placing reaction cups, and the reaction part 35 can rotate and drive the reaction cups in the placing positions to rotate for dispatching the reaction cups in the reaction tray. The sample addition site, the reagent addition site, the measurement site, and the like referred to herein may be placement sites at some positions in the reaction part 35, that is, the sample addition site, the reagent addition site, the mixing site, the measurement site, and the like are provided in the reaction part 35.
In some embodiments, the reaction member 35 may include an inner race portion and an outer race portion that may rotate independently or together; the inner ring part comprises one or more circles of tracks, and each circle of tracks is provided with a plurality of placing positions for incubating the reaction cup and dispatching the reaction cup among the placing positions of the inner ring part; the outer ring part comprises one or more circles of tracks, and each circle of tracks is provided with a plurality of placing positions for scheduling the reaction cups among the placing positions of the outer ring part. In fig. 6(b) is shown an outer ring portion having one turn of track, and an inner ring portion having three turns of track.
The measurement unit 36 measures the incubated mixture. For example, the measuring part 36 is used for incubating the reaction solution in the reaction cup at the measuring position to measure, and the test result is obtained. In some embodiments, the measuring unit 36 may be a photometric measuring unit, which can detect the light emission intensity of the mixed solution to be measured, calculate the concentration of the component to be measured in the sample through a calibration curve, and the like. In some embodiments, the assay part 36 may be separately disposed outside the reaction part 35.
Because the computer display screen 50 is generally located on the desk, the computer display screen 50 is located at a certain distance from the sample analysis main body 30 from the perspective of an operator, and it is not convenient to check and operate some information on the sample analysis device through the computer display screen 50 and the computer display screen 50. In consideration of the situation, the present application further introduces a status information screen 38 in the sample analyzer, so as to facilitate the operator to view and/or operate information and the like on the sample analyzer.
In the sample analysis device, at least two screens are introduced to view status information of the sample analysis device and/or to control the sample analysis device. The functions and roles of the computer display screen 50 and the status information screen 38 may be specifically configured as such.
In some embodiments, processor 37 is capable of executing instructions in response to operating computer display screen 50 and status information screen 38. The computer display 50 and the status information screen 38 may share a common processor 37. The operator can give commands to the sample analysis main body 30 by operating the computer display screen 50, and the operator can give commands to the sample analysis main body 30 through the status information screen 38.
In some implementations, the processor 37 obtains status information of the sample analysis device and generates first type display data and second type display data for transmission to the computer display screen 50 and the status information screen 38, respectively, for display. In some implementations, the first type of display data includes more information than the second type of data. Specifically, the first type of display data may include at least sample information, reagent status information, consumable status information, calibration information, quality control information, test result information, and maintenance information; the second type of display data may include status information of the reagent, and further, the second type of display data may further include consumable information.
In a specific communication connection mode, the processor 37 of the sample analysis main body 30 can be connected with the status information screen 38 in a wired mode for data transmission; the processor 37 of the sample analysis subject 30 may be connected by wire to the computer display screen 50 for data transfer.
In a particular mechanical configuration and positional arrangement, the status information screen 38 may be disposed in proximity to the reagent carrying part 33 of the sample analysis body 30. The computer display 50 may be disposed on the sample injection component 10, for example, the sample injection component 10 may have a housing, and generally, the housing can form a "load bearing platform" -for example, the upward side of the sample injection component 10; therefore, the computer display 50 can be disposed or placed on the housing of the sample injection component 10 facing upwards, and then connected to the processor 37 of the sample analysis main body 30 by a cable, or the computer display 50 can be disposed on the housing of the sample injection component 10 by a mechanical arm or a bracket.
The above is some description of the computer display 50 and the status information screen 38, and a further description of each is provided below.
In one embodiment, the status information screen 38 may also be wirelessly connected to the processor 37 of the sample analysis subject 30, both of which may be in wireless data communication; the status information screen may be held by the operator at this time, and one usage scenario may be that the user holds the status information screen 38 and stands in front of the sample analysis subject 30 for information viewing and/or manipulation, etc.
As described above, in one embodiment, the status information screen 38 may be fixedly disposed on the housing 1 of the sample analysis main body 30. For the convenience of user viewing and operation, the status information screen 38 may be provided in the housing on the side where the user operates the sample analysis main body 30, and further, the status information screen 38 may be provided in the vicinity of the reagent bearing member 33.
The above is a description about the position of the setting of the status information screen 38 and the connection manner. The information displayed on the status information screen is explained below.
Generally, the information displayed by the computer display screen 50 is more than the information displayed by the status information screen 38, the computer display screen 50 can acquire and display more information of the sample analysis device, and the status information screen 38 introduced in the present application is considered to be more pertinent in the aspect of information display. Thus, in some embodiments, the processor 37 obtains status information of the sample analysis device and generates a first type of display data and a second type of display data; the first type of display data includes state information of most or all of the sample analysis devices, and the second type of display data includes state information of a portion of the sample analysis devices; the computer display screen 50 receives the first type display data to display correspondingly; the status information screen 38 is adapted to receive the second type of display data for display accordingly. For example, the status information screen 38 displays information in the reaction part 35, such as which placing positions in the reaction part 35 are empty, which placing positions carry reaction cups, which reaction cups are under incubation, which reaction cups are under assay, and the like. In some embodiments, the second type of display data includes status information of the sample analysis device regarding the reagents and/or consumables; the status information screen is used to display status information of the sample analysis device with respect to the reagent and/or the consumable. It should be noted that the consumables of the embodiments herein refer to consumables other than reagents, for example, include consumables in a tray, consumables in a table top, consumables in a cabinet, and the like, and the consumables (i.e., consumables other than reagents) herein may typically be cleaning solutions, cleaning agents, and the like. The in-tray consumable material is a consumable material placed on a reagent position of the reagent tray 33, some of the consumable materials can be cleaning liquid, cleaning agent, diluent and the like, and the cleaning consumables such as the cleaning liquid, the cleaning agent and the like in the tray are generally used for cleaning a reagent needle; the countertop consumables may typically be cleaning fluids, cleaning agents, etc., and are typically used to clean sample needles, etc.
In some embodiments, the status information screen 38 may be a touch-sensitive display screen that a user may manipulate to operate the sample analysis device.
For example, in some embodiments, the processor 37 can control the movement of at least one of the sample dispensing member 32, the reagent carrier member 33, and the reagent dispensing member 34 in response to a touch operation on the status information screen 38. For example, the operator controls the movement of the sample dispensing unit 32 by the touch operation of the status information panel 38, controls the movement of the reagent dispensing unit 34 by the touch operation of the status information panel 38, controls the movement of the reagent holding unit 33 by the touch operation of the status information panel 38, and controls the rotation of the reagent disk 33 by the touch operation of the status information panel 38 when the reagent holding unit 33 is the reagent disk 33, so as to rotate an empty reagent site to an operation site for placing a reagent.
In some embodiments, the processor 37 is further capable of resetting the remaining amount of the consumable of at least a portion of the types of the sample analyzer in response to the touch operation of the status information screen 38. For example, a liquid storage barrel may be built in the sample analysis device, the liquid storage barrel stores cleaning liquid, when the cleaning liquid in the barrel is exhausted, the sample analysis device will alarm to inform an operator of replacement, and after the operator replaces a new liquid storage barrel, the residual amount of the cleaning liquid in the liquid storage barrel can be reset to a full load amount through touch operation of the status information screen 38.
The above are some illustrations of the status information screen 38. In the sample analyzer, one of the components that is relatively related to the operator is the reagent holding member 33, and therefore the operator needs to observe the information thereof to determine whether or not to perform reagent replenishment, the amount and position of reagent replenishment, and the like. The status information screen 38 is not described below as a screen for displaying the reagent and/or the consumable items exclusively, or a screen for controlling the reagent disk 33, and the status information screen is not described as the reagent screen 38.
In some embodiments, the reagent screen 38 is used to display status information of the sample analysis device regarding the reagent. For example, the processor 37 obtains status information of the sample analysis device regarding the reagent from the reagent tray 33 and generates display data, which the reagent screen 38 receives to display the status information of the sample analysis device regarding the reagent. In some embodiments, the status information of the sample analysis device about the reagent includes at least a name of the reagent, a position where the reagent is in the reagent tray, information that the remaining amount of the reagent is insufficient, information that the remaining amount of the reagent is zero, and information that the reagent level of the reagent container is not carried.
In some embodiments, the reagent screen 38 is also used to display status information of the sample analysis device regarding consumables, such as cleaning agents and cleaning fluids. For example, the processor 37 acquires the state information of the sample analysis apparatus about the consumable, and generates display data; the reagent screen 38 receives the display data to display status information of the sample analysis apparatus about consumables; the status information of the consumable part includes the name of the consumable part and the remaining amount information.
Thus, the reagent screen 38 is capable of displaying status information of the sample analysis device regarding the reagents and/or consumables.
In some specific embodiments, the reagent screen 38 is capable of displaying status information of the sample analysis device regarding reagents and/or consumables via one or more of an overview interface, and a reagent disk status interface. Each interface will be specifically described below.
In some embodiments, the reagent screen 38 displays information about the total amount of reagents required for the items in the reagent tray via an overview interface. The information on the total amount of reagent remaining for the items in the reagent tray may be information on whether or not the reagent is sufficient, and if not, how many items are indicated that the reagent remaining amount is insufficient. For example, the reagent screen 38 shows how much reagent is sufficient or how many items there are with insufficient reagent remaining. In specific implementation, the processor 37 acquires the residual amount information of the reagents required by each project from the reagent disk 33, and calculates the total residual amount information of the reagents required by the projects in the reagent disk 33 to generate corresponding display data; when the remaining amount of the reagent of the item is insufficient, the reagent screen 38 displays how many items have the insufficient remaining amount of the reagent through the overview interface or the overview interface to prompt the user, and otherwise, the reagent screen 38 may display a prompt that the remaining amount of the item is sufficient. Similarly, the reagent screen 38 displays the remaining amount information of the consumable substance as a whole through the overview interface, such as displaying a prompt that the consumable substance is sufficient or the remaining amount of the consumable substance is insufficient. FIG. 10 is an example of an overview interface showing that there are 3 items with low balance and sufficient consumable balance.
The reagent shield 38 may remain off during the start of the test after loading of reagent. In the testing process, when the processor 37 judges that the surplus of the reagent of the project is insufficient or when the processor 37 judges that the surplus of the consumable material is insufficient, the processor 37 can control the reagent screen 38 to exit the screen-off state, that is, the reagent screen 38 is lighted up at the moment, and an overview interface is displayed; to prevent inadvertent contact with the reagent screen 38, in some examples, the overview interface displayed at this time may be a locked overview interface. When the reagent screen 38 displays a locked overview interface, the processor controls the reagent screen to unlock and display an unlocked overview interface in response to an unlock operation of the reagent screen 38. The processor 37 is capable of controlling the reagent screen 38 to switch from the overview interface to the overview interface in response to a touch operation on the reagent screen 38. For example, in the example of FIG. 10, the user may enter the overview interface by clicking on the "enter System" button.
The reagent screen 38 displays the remaining amount information of the reagents required by each item in the reagent tray through the overview interface, for example, the remaining amount information of each item is displayed in the form of a card by taking the item as a unit, that is, each card corresponds to one item, and the card of the item can display information such as the name of the item, the reagent remaining amount of the item, and the like. In the case of the specific display, the reagent screen can display the remaining amount information of the reagent required for each item in the reagent disk in the overview interface in such a manner that the item whose remaining amount of the reagent is insufficient is displayed with priority. The priority display of the items with insufficient remaining amount may be performed automatically when the reagent screen 38 is switched from the overview interface to the overview interface, or may be performed by providing a button for priority viewing of the items with insufficient remaining amount on the overview interface, and in response to a click operation of the button, the processor 37 controls the reagent screen 38 to display the items with insufficient remaining amount preferentially. Similarly, the reagent screen 38 can also display information about the remaining quantities of each specific consumable item individually through the overview interface. Fig. 11 is an example, and it can be seen from the overview interface in the figure that the remaining amounts of the item Ca, the item Fe and the item CO2 are empty, the remaining amount of the item CRP is insufficient, the calibration of the item TP is expired, and these items are displayed at the forefront of the table and are highlighted, for example, with red.
When the reagent disk cover 33c is acquired in an open state, the processor 37 controls the reagent screen 38 to display a reagent disk status interface. In some embodiments, the reagent disk status interface displays a graphical representation of the reagent disk and/or reagent disk status information.
First, a schematic diagram of the reagent disk will be described.
In one embodiment, the reagent disk is provided with a graphic diagram at least showing the reagent positions of the reagent containers with insufficient residual quantity, the reagent positions of the reagent containers with zero residual quantity and the reagent positions without the reagent containers; the reagent sites on the graphical representation of the reagent tray correspond to the reagent sites on the reagent tray. In some embodiments, the reagent disk is further shown with reagent sites on the schematic representation of the disk where consumables are located. In one embodiment, the reagent screen 38 displays corresponding position number information, a reagent name, information that the remaining amount of the reagent is insufficient, information that the remaining amount of the reagent is zero, information whether a reagent container is loaded, and/or attribute information of a third party on a reagent site on a schematic diagram of a reagent disk through a reagent disk state interface. The reagent site may be displayed differently, for example, in different colors and/or marked with corresponding symbols, so that the operation can see information such as the insufficient remaining amount of the reagent, the zero remaining amount of the reagent, whether a reagent container is carried, and whether the reagent container is a third party attribute from the pictorial view. When the reagent disk cover 33c is in the open state, the reagent screen 38 also displays an operation area corresponding to the area covered by the reagent disk cover 33c on the reagent disk 33 on the reagent disk illustration, and the operation area is displayed in a manner different from other areas in the reagent disk illustration, for example, the operation area is displayed in white and the other areas are displayed in gray. In order to make the situation of the reagent level in the operation area more clear for the user, in an embodiment, the reagent screen 38 further displays a zoom area on the reagent disk status interface, and the zoom area is used for displaying the operation area in a zoom manner; through the amplification display effect of the amplification area, an operator can clearly see information such as the position, name and allowance of the loaded reagent in the current operation area, and the operator is assisted in quickly loading and unloading the loaded reagent; other positions of the non-operation area can also highlight the empty reagent bottles and the empty positions, so that a user can conveniently and quickly position the reagent bottles to other areas where reagents can be loaded and unloaded.
The operator can know which reagent positions on the reagent disk 33 have a small amount of reagent remaining, which reagent positions are positions not carrying reagent containers, and which reagent positions have zero amount of reagent remaining through the schematic diagram of the reagent disk, so that the operator can know which positions of the reagent disk 33 need to be moved to the operation area to replace the reagent.
In order to make the user more clearly understand the corresponding information of reagent loading, in some embodiments, the reagent screen 38 further displays a list to be loaded on the reagent tray status interface, where the list to be loaded displays the name of the item to be loaded with reagent, the number of reagent bottles, and the list to be loaded also displays the name of the reagent track where the reagent is placed with the item to be loaded with reagent. Of course, it is understood that when the reagent tray 33 is also loaded with tray consumables such as cleaning solution and/or cleaning solution for cleaning reagent needles, the list to be loaded may also have the name of the consumables to be loaded on the tray, the number of bottles, and the location of the reagent station.
The disk state information of the reagent will be described.
The reagent disk state information may be a state indication indicating that the reagent disk cover 33c is in an open state and the cover is opened, a state indication during scanning in which the reagent is being scanned after the reagent disk 33 is loaded with the reagent, a state indication that the reagent disk 33 is malfunctioning, a state indication that the reagent disk 33 is rotating, a state indication that the reagent disk 33 is in residual amount detection, or the like. In one implementation, the processor 37 obtains status information for the reagent tray and then controls the reagent screen 38 to display a corresponding text prompt next to the graphic representation of the reagent tray.
Fig. 12, 13 and 14 are several examples of reagent disk status interfaces. The white sector in the schematic view of the reagent disk in fig. 12 is the operating area, and the reagent sites 6 and 37 are gray and do not show the reagent names, indicating that the two reagent sites are empty, i.e. not carrying reagent containers; reagent stations 1, 5, 7, 18 and 24 are white and correspondingly indicated by reagent names, thus indicating that the remaining reagent amount at these reagent stations is zero, i.e. carrying empty reagent containers; in some examples, the remaining amount on the reagent site may be displayed in a cell, where the reagent site is white, i.e., the cell has seen the bottom, indicating that the remaining amount is zero; reagent station 31 in the figure carries an in-tray consumable, named DA, and reagent station 33 in the figure carries a third party reagent. Fig. 13 also shows the list to be loaded, which may be of a collapsible design, and a button is provided on the list frame, and the user can call out or hide the list to be loaded by clicking the button. Fig. 14 shows the reagent tray cover 33a having been closed by the operator, at which time the processor 37 controls, for example, a scanner provided in the reagent tray 33 to scan the reagent in the reagent tray. The letter R in fig. 12, 13 and 14 means a reagent disk. In addition, it is understood that the drawing shows various symbols and forms of the empty positions, the empty reagent bottles, the consumables, the third-party reagents, and the like, and only one of them is illustrated in the drawing.
The above is an explanation in which the operator views the status information of the sample analyzer about the reagent through the reagent screen 38. In some implementations, the operator may control the reagent disk 33 to rotate accordingly via the reagent screen 38, as described in more detail below.
The processor 37 is capable of controlling the reagent disk 33 to rotate accordingly in response to a touch operation on the reagent screen 38. In some specific embodiments, the processor 37 can control the reagent disk 33 to rotate correspondingly in response to a touch operation of dragging the schematic diagram of the reagent disk on the reagent screen 38 to rotate; the user controls the reagent disk 33 to rotate accordingly, for example by dragging a graphical representation of the reagent disk to rotate on the reagent screen 38. In some embodiments, the reagent disk is divided into a plurality of zones, e.g., 4 zones, and in response to a click operation on any one zone, the processor 37 controls the clicked zone to pivot to an operating zone in the reagent disk that corresponds to the actual zone. In this way, the operator performs touch operation on the schematic diagram of the reagent disk on the reagent screen 38, so as to control the rotation of the reagent disk 33, for example, to transfer the reagent positions with insufficient remaining amount, zero remaining amount, and empty remaining amount to the operation area, so as to facilitate the replacement of the reagent. In order to prevent an operator from misunderstanding the reagent screen 38 and causing the reagent disk 33 to rotate during the reagent loading process, a lock key may be introduced at the interface of the reagent disk state, when the operator clicks the lock key, the processor 37 may lock the rotation authority of the reagent disk 33 in response to a touch operation performed on the lock key, after the rotation authority of the reagent disk 33 is locked, the operator may no longer control the reagent disk 33 to rotate in a manual manner unless the reagent disk 33 is unlocked, so that the authority of the reagent disk 33 is released, and the operator may control the rotation of the reagent disk 33 by performing a touch operation on the reagent screen 38 on the schematic diagram of the reagent disk.
For example, in the case that the test is not started after the reagent tray is turned on every day or the current test is finished before the reagent tray is turned off every day, when the reagent tray needs to be replenished with reagent, the reagent tray cover 33c may be directly opened, and then the reagent screen 38 may be used to complete the reagent replacement. If the reagent disk is in the test process, the user can firstly send a reagent adding pause command to the sample analysis device, and after the reagent disk enters the reagent pause state from the test state and stops rotating due to the test, the operator can open the reagent disk cover 33c to complete reagent replacement. In particular, the processor 37 is capable of controlling the reagent disk 33 from the testing state to the reagent pause state in response to a reagent pause instruction while the reagent disk 33 is in the testing state. In some embodiments, the reagent screen displays a reagent pause key, such as the reagent pause key in fig. 10 and 11, and in response to a touch operation of the reagent pause key, the reagent screen issues a reagent adding pause instruction; in response to the reagent pause instruction, the processor 37 controls the reagent screen 38 to display a time prompt to indicate how long the reagent tray cover can be opened for reagent loading; when the time is reached, the processor 37 controls the reagent screen 38 to display a prompt allowing the reagent disk lid to be opened.
The operator can change the reagent at the reagent site of the reagent disk in the operation area by rotating the corresponding area of the reagent disk 33 to the operation area through the reagent screen 38. In order to carry as much reagent as possible, some sample analyzers also have reagent trays that are relatively large, and therefore, when an operator stands in front of the sample analyzer to rotate the reagent trays and replace the reagent, the reagent trays may have a relatively large structure, which may cause difficulty in operation for an operator with a low height, such as difficulty in reaching reagent positions at some corners in the operation area. To address this issue, in some embodiments, the reagent disk is divided into multiple partitions, and the number of partitions can be set so that a specific area on the reagent disk can be more finely rotated into an operating area, especially a more optimal sub-area of the operating area, to enhance the experience of an operator who is not tall, as described in detail below.
In some embodiments, the reagent disk status interface displays a graphical representation of the reagent disk divided into a plurality of zones; in response to the partition setting instruction, the processor 37 controls the setting of the schematic of the reagent disk to the corresponding number of partitions. For example, the operator may set the schematic of the reagent disk to 4 partitions, 8 partitions, etc. by pulling down the menu. As described above, in response to a click operation on any one of the partitions, the processor controls the clicked partition to rotate into the operation region in the region actually corresponding to the reagent disk; in one embodiment, the operating zone includes a sub-zone to which the processor 37 controls the clicked section to pivot within the reagent disk 33 to the actual corresponding zone in response to a click operation on any one of the sections within the schematic of the reagent disk.
In order to enable an operator to switch the partition number more conveniently, a partition switching key can be introduced into the reagent disk state interface, and a number for representing the current partition number can be displayed on the partition switching key; in response to a click operation on the switch button, the processor 37 controls the switching of the schematic of the reagent disk to a corresponding number of divisions. For example, fig. 15 and 16 are two examples; an example of two reagent disks 33 is shown.
The above is some descriptions about the reagent screen 38, and the following describes how the operator uses the reagent screen 38 to complete reagent loading, respectively, by taking two scenarios of batch loading after daily power-on and reagent loading during testing as examples.
Scene one: daily after start-up batch loading
After starting the machine, the operator can open the reagent disk cover 33c, the reagent screen 38 displays the reagent disk state interface, the operator views the list to be loaded from the reagent disk state interface, then controls the reagent disk 33 to rotate by touching the shape-indicating diagram of the reagent disk in the reagent disk state interface, then puts the reagent into the reagent disk, and finishes reagent batch loading on the reagent disk 33 by continuously controlling the reagent disk 33 to rotate and putting the reagent into the reagent disk 33.
Scene two: additional reagents in the test procedure
When the operator sees from the overview interface of the reagent screen 38 that the remaining amount of the items is insufficient, the operator clicks a reagent pause button on the reagent screen 38, so that the reagent disk 33 enters a reagent pause state from the test state, then the operator opens the reagent disk cover 33c, the reagent screen 38 displays a reagent disk state interface, the operator views a list to be loaded from the reagent disk state interface, then controls the reagent disk 33 to rotate by touching the representation of the reagent disk in the reagent disk state interface, then puts the reagent into the reagent disk, and possibly takes out the reagent container with the empty remaining amount from the reagent disk, so as to complete the reagent loading on the reagent disk.
The sample analysis device of the present application may be provided with two screens, such as a computer screen 50 and a reagent screen 38, which may also be cooperatively displayed.
For example, the processor 37 estimates the required amount of the reagent and/or consumable material on the day and controls the computer display screen 50 to display a list of the required amount of the reagent and/or consumable material; the processor 37 calculates a list to be loaded of the reagents and/or consumables according to the estimated required amount of the reagents and/or consumables on the current status information of the reagents and/or consumables of the sample analyzer, and controls the reagent screen to display the list to be loaded of the reagents and/or consumables. In the list to be loaded calculated by the processor 37, the processor 37 may intelligently recommend the location of loading of the new vial of reagent based on factors affecting cross-contamination, test efficiency, etc.
For another example, the computer screen 50 displays a reagent pause button, and the reagent screen 38 displays a reagent pause button, which both function in the same way, and the processor 37 controls the reagent disk 33 to enter the reagent pause state from the test state no matter which reagent pause button is clicked by the operator. Further, in response to clicking the reagent pause button, the processor 37 controls a time indicator to be displayed on both the computer display 50 and the reagent screen 38 to indicate how long the reagent disk cover 33c can be opened for reagent loading. Further, when time has expired, the processor 37 controls both the computer display 50 and the reagent screen 38 to display a prompt to allow the reagent disk lid to be opened.
Whether the reagent disk cover 33c is opened after the reagent pause button is clicked during the test process or the reagent disk cover 33c is opened under such a non-test condition as before the test after the test is started, how the subsequent reagent screen 38 displays the reagent disk, and how the operator can control the reagent disk to rotate through the reagent screen 38, has been described in detail above, and is not described herein again.
When the operator closes the reagent disk cover 33c, the processor 37 can acquire that the reagent disk cover 33c is changed from the open state to the closed state, thereby controlling the reagent in the reagent disk 33 to be scanned and controlling the computer display 50 and the reagent screen 38 to display a prompt for the test to be resumed.
The above are some examples of the combined display of the computer screen 50 and the reagent screen 38.
Some examples are given below to illustrate how the user can load the reagent by the present invention. The following two scenarios of batch loading after daily power-on and reagent loading during testing are used as examples to illustrate how the operator uses the reagent screen 38 to complete reagent loading.
Scene one: daily after start-up batch loading
The processor 37 can estimate the required amount of the reagent and/or consumable on the current day, and calculate the list to be loaded of the reagent and/or consumable according to the current status information of the reagent and/or consumable of the sample analyzer without the need for the operator to count and calculate the list. As shown in fig. 17(a), the operator selects the daily requirement option and clicks the confirmation in the lower right corner, and the processor 37 calculates the list to be loaded. The processor 37 controls the display of the list to be loaded on the computer display screen 50, and an operator can select to print the list to be loaded without manually copying by the user; then, an operator can go to a reagent warehouse to take out the reagent according to the printed list to be loaded; the list to be loaded on the computer screen 50 may be synchronized to the reagent screen 38, and the user may look directly at the reagent screen 38 after retrieving the reagent up to the reagent and location to be replenished. After the operator has retrieved the reagent, and before the sample analyzer, the reagent disk cover 33c is opened, which triggers the reagent screen 38 to display the reagent disk status interface.
As an example of the reagent disk state interface shown in fig. 17(b), it can be seen that the region of the reagent disk a in the figure is the operation region, and is displayed in an enlarged manner, and the reagent level of the empty bottle and the reagent level of the empty position are both displayed in the figure for the convenience of the operator to find; the operator may also click on the "bottle with less remaining" button, so that the reagent with insufficient remaining in the reagent tray 33 is highlighted, as shown in fig. 17(c), which is an example. The figure is an example of dividing the schematic diagram of the reagent disk into 4 partitions, namely A, B, C and D, and an operator clicks A, B, C or D partition to rotate the corresponding partition to the operation region in the actually corresponding region of the reagent disk 33; the operator clicks on the viewing loading list on the right side of the figure, and can call out the loading list to be viewed, as shown in fig. 17(d) is an example. When the sample analyzer has a plurality of reagent disks 33, for example, a first reagent disk 33 loaded with the mixed reagent R1 and a second reagent disk 33 loaded with the trigger reagent R2, when the first reagent disk 33 is loaded, the operator can switch to the second reagent disk 33 by simply clicking the graphic diagram of the second reagent disk 33, and the interface has a pop-up window to indicate that the switching to the R2 disk view is successful, as shown in fig. 17 (e).
To prevent the operator from accidentally touching the screen during loading and causing the reagent tray to suddenly rotate while reagent is being loaded, a screen lock function may be provided, such as a slide lock button in the upper right corner of the figure, and when locked, the reagent tray status interface may be shaded with a grey color, as shown in fig. 17(f), which is an example.
After the operator has replenished the reagent, the reagent tray cover 33c is closed, the reagent screen 38 displays that the reagent tray is processing the scan and displays the scan count-down, and fig. 17(g) is an example of the display of the reagent screen; in some instances, the computer screen 50 may also display that the reagent disk is processing a scan and that the scan count down is being displayed.
After the user finishes replenishing the reagent, the user can click on other consumables on the right side on the reagent disk status interface to continue replenishing the table-top consumables, the cabinet consumables and the like, for example, fig. 17(h) is an example; after the completion of replenishment, the balance reset can be clicked, and the balance of the consumables is refreshed to 100%.
After the user has replaced the reagents and consumables, the reagent screen 38 jumps back to the overview interface after the reagent tray has been scanned. In some embodiments, after the user has replaced the reagent and consumables and the reagent tray has been scanned, the reagent screen 38 jumps back to the locked overview interface-for example, FIG. 17(i) is an example; further, if the user does not perform any touch operation while the reagent screen 38 is displaying the locked overview interface for a while, the reagent screen 38 enters the screen-off state.
Scene two: additional reagents in the test procedure
During the test, if the reagent or consumable is insufficient, the reagent screen 38 will light up and display an overview interface, which can remind the operator with a good notice, and during the test, the operator can know that the reagent or consumable is insufficient as long as the operator sees that the reagent screen 38 is light, and fig. 18(a) is just an example. After unlocking the screen and clicking the enter system button, the operator can enter the overview interface from the overview interface to specifically check which items or consumables have insufficient allowance, and fig. 18(b) is an example; then, the button for preferentially checking the insufficient margin can be clicked, so that the items with insufficient margin can be automatically sorted to the front, namely, preferentially displayed, and fig. 18(c) is an example. After the operator finishes taking the reagent or the consumable, the operator clicks a reagent pause button of the reagent screen 38, the reagent screen 38 displays the countdown, for example, fig. 18(d) is an example, and the computer display screen 50 can also display the countdown synchronously; after the time is reached, the reagent screen 38 displays a prompt prompting the operator to open the reagent disk cover, the computer display 50 also displays a prompt prompting the operator to open the reagent disk cover, for example, fig. 18(e) shows an example in which the computer display 50 displays a prompt prompting the operator to open the reagent disk cover, and fig. 18(f) shows an example in which the reagent screen 38 displays a prompt the operator to open the reagent disk cover.
Opening the reagent disk cover 33c triggers the reagent screen 38 to display the reagent disk status interface. The subsequent steps may refer to the flow after opening the reagent tray cover 33c in the batch loading process after daily startup in the scenario one, which is not described herein again.
Fig. 18(g) shows an example of the scan countdown displayed on the reagent screen 38 after the reagent disk cover is closed, and the sample analyzer automatically resumes the test after the scan time is over.
Fig. 19 and 20 show a view of a reagent disk in failure and scanning in the interface of the reagent disk state.
In the testing process, when an operator needs to load a reagent, in order to quickly enter a reagent replacing stage, reduce the waiting time of the operator for the reagent tray to stop, and not affect the normal performance of other tests, the processor 37 can respond to a reagent pause instruction, for example, a reagent pause instruction triggered by the operator clicking a reagent pause button on the reagent screen 38 or the computer display screen 50, the processor controls the reagent tray 33 to enter a reagent pause state from a testing state and stop rotating, controls the sample injection component 10 to dispatch the sample, controls the sample injection component 32 to suck the sample from the sample injection component 10 and inject the sample into the reaction cup, controls the reaction component 35 to incubate a mixed solution formed by the sample and the reagent in the reaction cup, and controls the determination component 36 to determine the incubated mixed solution. In order to prevent the movable unit of the sample analyzer, typically, the sample dispensing member 32, from causing personal injury to the operator, referring to fig. 21, the sample analyzer may further include a protection cover 39; the shield 39 is provided in such a manner that the reagent disk cover can be opened and closed, and covers other test components, for example, the shield 39 covers a part of the reagent disk 33, and covers the sample introduction part 10, the sample dispensing part 32, the reagent dispensing part 34, the reaction part 35, and the like. The hood 39 is openable and closable. Fig. 21 is a partial plan view of the sample analyzer, and shows an example in which the sample analyzer has two reagent disks 33.
In the above example, the processor 37 responds to the reagent adding pause instruction, and controls the reagent disk 33 to enter a pause state after the current action is executed, the waiting time is less than 10 seconds, and the test actions of other components are not interrupted, at this time, the operator can directly open the reagent disk cover to replace the reagent, and after the reagent is replaced, the operator closes the reagent disk cover, and the sample analyzer automatically resumes the normal test flow. The whole replacement operation process is simple and quick, the reagent consumable replenishment efficiency in the test process can be greatly improved, and the meaningless waiting time of a user is reduced.
The above is some description of the sample analysis system and sample analysis device of the present application. Also disclosed in some embodiments is a sample analysis method that can be applied to the sample analysis device of any of the embodiments herein, as described in detail below.
Referring to fig. 22, the sample analysis method in some embodiments includes the following steps:
step 100: controlling to suck a sample to be injected and injecting the sample into the reaction cup.
Step 110: controlling to suck the reagent from the reagent tray and inject the reagent into the reaction cup.
Step 120: and controlling the incubation of the mixed solution formed by the sample and the reagent in the reaction cup.
Step 130: the control measures the incubated mixture.
In the above measurement process, the sample analysis method further comprises the steps of:
step 200: status information of the sample analysis device about the reagent is acquired from the reagent tray.
In some embodiments, the status information of the sample analysis device about the reagent includes at least a name of the reagent, a position where the reagent is in the reagent tray, information that the remaining amount of the reagent is insufficient, information that the remaining amount of the reagent is zero, and information that the reagent level of the reagent container is not carried.
Step 210: the control reagent screen displays status information of the sample analysis device regarding the reagent.
In some embodiments, the step 210 of controlling the reagent screen to display the status information of the sample analysis device about the reagent may include: controlling a reagent screen to display status information of the sample analysis device about the reagent via one or more of an overview interface, and a reagent disk status interface; the overview interface displays the overall surplus information of the reagents required by the items in the reagent tray; the overview interface respectively displays the residual amount information of the reagents required by each project in the reagent tray; the reagent disk state interface displays the schematic diagram of the reagent disk and the reagent disk state information. Further description of the overview interface, overview interface and reagent disk state interface can be found above and will not be described herein.
In some examples, the state information of the sample analyzer about consumables is also obtained in step 200, and accordingly, the reagent screen is controlled by step 210 to display the state information of the sample analyzer about consumables, the state information of the consumables including the names of the consumables and the balance information; controlling the reagent screen to display status information of the sample analysis apparatus about consumables includes: controlling the reagent screen to display status information of the sample analysis device about the consumable through one or more of the overview interface, the overview interface; the overview interface displays the total allowance information of the consumables; the overview interface displays the individual allowance information of each specific consumable.
Referring to fig. 23, the sample analysis method in some embodiments includes the following steps:
step 100: controlling to suck a sample to be injected and injecting the sample into the reaction cup.
Step 110: controlling to suck the reagent from the reagent tray and inject the reagent into the reaction cup.
Step 120: and controlling the incubation of the mixed solution formed by the sample and the reagent in the reaction cup.
Step 130: the control measures the incubated mixture.
In the above measurement process, the sample analysis method further comprises the steps of:
step 300: status information of the sample analysis device about the reagent is acquired from the reagent tray.
In some embodiments, the status information of the sample analysis device about the reagent includes at least a name of the reagent, a position where the reagent is in the reagent tray, information that the remaining amount of the reagent is insufficient, information that the remaining amount of the reagent is zero, and information that the reagent level of the reagent container is not carried.
Step 310: and when the obtained reagent disk cover is in an open state, controlling the reagent screen to display a reagent disk state interface. In some embodiments, the reagent disk state interface displays a schematic diagram of a reagent disk, the schematic diagram of the reagent disk at least displays a reagent site where a reagent container with insufficient residual quantity is located, a reagent site where a reagent container with zero residual quantity is located and a reagent site where no reagent container is carried, and the reagent site on the schematic diagram of the reagent disk corresponds to the reagent site on the reagent disk. In some embodiments, a loading list is further displayed on the reagent disk state interface, and the loading list displays the item name, the number of reagent bottles and the like of the reagent to be loaded. For further description of the disk interface of the reagent, see above, no further description is given here.
Step 320: when the reagent tray cover is changed from an open state to a closed state, the reagent in the reagent tray is controlled to be scanned, and after the scanning is finished, the reagent screen is controlled to display an overview interface. In some embodiments, the overview interface displays information about the amount of reagent in the reagent tray required for the items in the reagent tray. For further description of the overview interface, reference may be made to the above description and will not be repeated here.
Step 330: and after the scanning is finished, controlling the reagent screen to display the overview interface, further controlling to lock the overview interface, and controlling the reagent screen to enter a screen-off state after preset time.
Step 340: in the test process, when the surplus of the reagent with the project is judged to be insufficient, controlling the reagent screen to exit a screen-off state, and displaying an overview interface; further, it may be an overview interface where the display is locked.
Step 350: when the reagent screen displays the locked overview interface, controlling the reagent screen to be unlocked in response to the unlocking operation of the reagent screen; and responding to the touch operation of the reagent screen, and controlling the reagent screen to be switched from the overview interface to the overview interface. The overview interface displays the residual amount information of the reagents required by each item in the reagent tray. The method comprises the following steps that after a user sees a locked overview interface, unlocking operation is carried out on a reagent screen, the reagent screen is changed from a locked state to an unlocked state, the user can carry out touch operation on the overview interface on the reagent screen, and then the reagent screen can be switched to the overview interface from the overview interface.
Referring to fig. 24 and 25, the sample analysis method in some embodiments includes the following steps:
step 100: controlling to suck a sample to be injected and injecting the sample into the reaction cup.
Step 110: controlling to suck the reagent from the reagent tray and inject the reagent into the reaction cup.
Step 120: and controlling the incubation of the mixed solution formed by the sample and the reagent in the reaction cup.
Step 130: the control measures the incubated mixture.
In the above measurement process, the sample analysis method further comprises the steps of:
step 410: and controlling the reagent disk to correspondingly rotate in response to the touch operation of the reagent screen.
Specifically, status information of the sample analysis apparatus about the reagent is acquired from the reagent tray; the control reagent screen is used for receiving display data to display the state information of the sample analysis device about the reagent; the control reagent screen is used for receiving display data to display the status information of the sample analysis device about the reagent, and comprises: the reagent screen displays a reagent disk state interface, and the reagent disk state interface at least displays a graphic display of the reagent disk; at least the reagent position of the reagent container with insufficient residual quantity, the reagent position of the reagent container with zero residual quantity and the reagent position without the reagent container are displayed on the schematic diagram of the reagent disk; the reagent sites on the graphical representation of the reagent tray correspond to the reagent sites on the reagent tray. Further description of the disk state interface of the reagent can be found above and will not be repeated here.
Step 410 may be a touch operation of rotating a graphic drawing dragging the reagent disk on the reagent screen, and controlling the reagent disk to rotate correspondingly. The reagent disk is divided into a plurality of partitions, and step 400 may also be to control the clicked partition to rotate to an operation area in the reagent disk corresponding to the actual area in response to a click operation on any one partition.
In the reagent loading process, in order to prevent an operator from misunderstanding a reagent screen to cause the reagent disk to rotate, a locking key can be introduced into a reagent disk state interface, the rotation authority of the reagent disk can be controlled and locked in response to touch operation on the locking key, after the rotation authority of the reagent disk is locked, the operator can not control the reagent disk to rotate in a manual mode any more unless the reagent disk is unlocked, so that the authority of the reagent disk is released, and the operator can control the rotation of the reagent disk by performing touch operation on a schematic diagram of the reagent disk on the reagent screen.
The reagent screen can also display a reagent pause button. Step 400: and responding to the touch operation of the reagent pause key, and controlling the reagent disk to enter a reagent pause state from a test state. Further, in response to the touch operation of the reagent pause key, the step 400 further controls the reagent screen to display a time prompt, so as to prompt how much time later the reagent tray cover can be opened for reagent loading; when the time is up, the reagent screen is controlled to display a prompt that allows the reagent disk cover to be opened.
Referring to fig. 26, the sample analysis method in some embodiments includes the following steps:
step 100: controlling to suck a sample to be injected and injecting the sample into the reaction cup.
Step 110: controlling to suck the reagent from the reagent tray and inject the reagent into the reaction cup.
Step 120: and controlling the incubation of the mixed solution formed by the sample and the reagent in the reaction cup.
Step 130: and controlling to determine the incubated mixed liquor.
In the above measurement process, the sample analysis method further comprises the steps of:
step 500: in the test process, in response to a reagent adding pause instruction, the reagent disk is controlled to enter a reagent pause state from a test state and stop rotating, the sample injection component is controlled to dispatch a sample, the sample injection component is controlled to suck the sample from the sample injection component and inject the sample into the reaction cup, the reaction component is controlled to incubate a mixed solution formed by the sample and the reagent in the reaction cup, and the determination component is controlled to determine the incubated mixed solution.
Referring to fig. 27 and 28, a method for controlling a sample analyzer in some embodiments includes the following steps:
step 600: the control reagent screen displays a reagent disk state interface, the reagent disk state interface at least displays a shape display diagram of the reagent disk, and the shape display diagram of the reagent disk is divided into a plurality of subareas.
In some embodiments, the reagent disk state interface further comprises a partitioned switch key; step 610: and in response to the clicking operation of the switching key, controlling the icon of the reagent disk to be switched into the corresponding number of subareas.
Step 620: in response to the clicking operation on any one of the partitions, the processor controls the clicked partition to rotate to a preset operation area in the reagent disk corresponding to the actual area. In some examples, the operation region includes a sub-region, and step 620 controls the clicked partition to rotate to the sub-region in the reagent disk corresponding to the actual region in response to the click operation on any one partition.
Referring to fig. 29, the sample analysis method in some embodiments includes the following steps:
step 700: and estimating the required quantity of the reagent and/or the consumable on the day, and controlling a computer display screen to display a list of the required quantity of the reagent and/or the consumable.
Step 710: and calculating a list to be loaded of the reagents and/or consumables according to the estimated demand of the reagents and/or consumables on the current date and the current state information of the reagents and/or consumables of the sample analysis device, and controlling the reagent screen to display the list to be loaded of the reagents and/or consumables.
Reference is made herein to various exemplary embodiments. However, those skilled in the art will recognize that changes and modifications may be made to the exemplary embodiments without departing from the scope hereof. For example, the various operational steps, as well as the components used to perform the operational steps, may be implemented in differing ways depending upon the particular application or consideration of any number of cost functions associated with operation of the system (e.g., one or more steps may be deleted, modified or incorporated into other steps).
In the above embodiments, the implementation may be wholly or partially realized by software, hardware, firmware, or any combination thereof. Additionally, as will be appreciated by one skilled in the art, the principles herein may be reflected in a computer program product on a computer readable storage medium, which is pre-loaded with computer readable program code. Any tangible, non-transitory computer-readable storage medium may be used, including magnetic storage devices (hard disks, floppy disks, etc.), optical storage devices (CD-to-ROM, DVD, Blu-Ray discs, etc.), flash memory, and/or the like. These computer program instructions may be loaded onto a general purpose computer, special purpose computer, or other programmable data processing apparatus to produce a machine, such that the instructions which execute on the computer or other programmable data processing apparatus create means for implementing the functions specified. These computer program instructions may also be stored in a computer-readable memory that can direct a computer or other programmable data processing apparatus to function in a particular manner, such that the instructions stored in the computer-readable memory produce an article of manufacture including means for implementing the function specified. The computer program instructions may also be loaded onto a computer or other programmable data processing apparatus to cause a series of operational steps to be performed on the computer or other programmable apparatus to produce a computer implemented process such that the instructions which execute on the computer or other programmable apparatus provide steps for implementing the functions specified.
While the principles herein have been illustrated in various embodiments, many modifications of structure, arrangement, proportions, elements, materials, and components particularly adapted to specific environments and operative requirements may be employed without departing from the principles and scope of the present disclosure.

Claims (11)

1. A sample analysis apparatus, comprising:
the sample introduction part is used for dispatching a sample;
the sample dispensing component is used for sucking the sample on the sample feeding component and discharging the sample into the reaction cup;
a reagent tray having a plurality of reagent sites, wherein the reagent sites are for carrying reagents; the reagent tray can rotate and drive the reagent carried by the reagent tray to rotate;
a reagent dispensing member for sucking a reagent and discharging the reagent into a reaction cup;
a reaction part for incubating a mixed solution formed by a sample and a reagent in the reaction cup;
a measurement unit for measuring the incubated mixture;
a processor and a touch-sensitive reagent screen, wherein:
the reagent screen is used for displaying a reagent disk state interface, the reagent disk state interface at least displays a shape representation diagram of the reagent disk, and the shape representation diagram of the reagent disk is divided into a plurality of subareas; in response to a partition setting instruction, the processor controls setting the schematic of the reagent disk to a corresponding number of partitions;
in response to the clicking operation on any one of the partitions, the processor controls the clicked partition to rotate to a preset operation area in the reagent disk corresponding to the actual area.
2. The sample analysis apparatus of claim 1, wherein the manipulation zone comprises a sub-zone, and in response to a click manipulation of any one of the partitions, the processor controls the clicked partition to pivot to the sub-zone in an area of the reagent disk that actually corresponds to the clicked partition.
3. The sample analysis device of claim 1, wherein the reagent disk format interface further comprises a zoned toggle button;
in response to a click operation of the switch key, the processor controls to switch the schematic of the reagent disk to a corresponding number of divisions.
4. The sample analyzer of claim 3 wherein the switch button further displays a number indicating the number of current partitions.
5. The sample analysis device according to claim 1, wherein the default number of partitions of the schematic of the reagent disk is 4.
6. The sample analysis device of any one of claims 1 to 5, wherein the reagent tray further has a reagent tray cover that is openable and closable; when the reagent disk cover is in the open state, the reagent screen further displays an operation area corresponding to the area covered by the reagent disk cover on the reagent disk on the schematic diagram of the reagent disk, and the operation area is displayed in a mode different from other areas in the schematic diagram of the reagent disk.
7. A method for controlling a sample analyzer, the sample analyzer including a reagent disk and a touch-sensitive reagent screen, the method comprising:
controlling the reagent screen to display a reagent disk state interface, wherein at least a shape display diagram of the reagent disk is displayed on the reagent disk state interface, and the shape display diagram of the reagent disk is divided into a plurality of subareas;
in response to the clicking operation on any one of the partitions, the processor controls the clicked partition to rotate to a preset operation area in the reagent disk corresponding to the actual area.
8. The method for analyzing a sample according to claim 7, wherein the reagent disk state interface further comprises a partitioned switch button;
and responding to the clicking operation of the switching key, and controlling the icon of the reagent disk to be switched into a corresponding number of subareas.
9. The sample analysis method according to claim 7 or 8, wherein when the acquired reagent disk cover is in an open state, the reagent screen further displays an operation area corresponding to an area covered by the reagent disk cover on the reagent disk on the schematic diagram of the reagent disk, the operation area being displayed in a manner different from other areas in the schematic diagram of the reagent disk; wherein the reagent disk has a reagent disk cover that can be opened and closed.
10. The method for controlling a sample analyzer according to claim 7, wherein the operation area includes a sub area, and in response to a click operation on any one of the partitions, the area of the reagent disk to which the clicked partition is actually located is controlled to rotate.
11. A computer-readable storage medium, characterized by comprising a program executable by a processor to implement the method of any one of claims 7 to 10.
CN202011338297.4A 2020-11-25 2020-11-25 Sample analysis device and control method thereof Pending CN114544991A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202011338297.4A CN114544991A (en) 2020-11-25 2020-11-25 Sample analysis device and control method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202011338297.4A CN114544991A (en) 2020-11-25 2020-11-25 Sample analysis device and control method thereof

Publications (1)

Publication Number Publication Date
CN114544991A true CN114544991A (en) 2022-05-27

Family

ID=81660025

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202011338297.4A Pending CN114544991A (en) 2020-11-25 2020-11-25 Sample analysis device and control method thereof

Country Status (1)

Country Link
CN (1) CN114544991A (en)

Similar Documents

Publication Publication Date Title
JP3990944B2 (en) Automatic analyzer
US7776264B2 (en) Automatic analyzer
CN101726615B (en) Sample analyzer, reagent information displaying method and control system
US20140119994A1 (en) Sample analyzer
US11662356B2 (en) Biochemical analysis apparatus and method of operating the same
JP6429753B2 (en) Automatic analyzer and automatic analysis method
JP2012233923A (en) Auto-analyzer
JP6026753B2 (en) Automatic analyzer
JP6439044B2 (en) Automatic analyzer
CN114544991A (en) Sample analysis device and control method thereof
CN114544986A (en) Sample analysis device and method
CN114544989A (en) Sample analysis device and method
CN114544985A (en) Sample analysis device and system
CN114545001A (en) Sample analysis device and method
CN114545002A (en) Sample analysis device and method
JP2023018144A (en) automatic analyzer
US20230056397A1 (en) Automatic analysis device, display system of automatic analysis device, and display method in automatic analysis device
US20230228777A1 (en) Automatic analyzer
CN115343487A (en) Sample analysis system and reagent specifying method
JP2005091277A (en) Automatic analyzer
WO2024042801A1 (en) Automatic analysis device and control method for same
CN117849370A (en) Sample analysis device and sample analysis system
WO2023008069A1 (en) Automatic analysis device, and guidance method used in automatic analysis device
CN117849368A (en) Sample analysis device
CN117871876A (en) Sample analysis device

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination