CN114544923A - Helicobacter pylori detector - Google Patents
Helicobacter pylori detector Download PDFInfo
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- CN114544923A CN114544923A CN202210279794.4A CN202210279794A CN114544923A CN 114544923 A CN114544923 A CN 114544923A CN 202210279794 A CN202210279794 A CN 202210279794A CN 114544923 A CN114544923 A CN 114544923A
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- 241000590002 Helicobacter pylori Species 0.000 title claims abstract description 42
- 229940037467 helicobacter pylori Drugs 0.000 title claims abstract description 42
- 238000004659 sterilization and disinfection Methods 0.000 claims abstract description 29
- 239000000645 desinfectant Substances 0.000 claims abstract description 17
- 239000007788 liquid Substances 0.000 claims description 30
- 230000000903 blocking effect Effects 0.000 claims description 8
- 230000001954 sterilising effect Effects 0.000 claims 1
- 238000001514 detection method Methods 0.000 abstract description 25
- 238000005070 sampling Methods 0.000 abstract description 24
- 238000000034 method Methods 0.000 abstract description 8
- 206010011409 Cross infection Diseases 0.000 abstract description 6
- 206010029803 Nosocomial infection Diseases 0.000 abstract description 6
- 230000002421 anti-septic effect Effects 0.000 description 23
- 239000000243 solution Substances 0.000 description 23
- 238000012360 testing method Methods 0.000 description 9
- 239000004202 carbamide Substances 0.000 description 8
- 210000002784 stomach Anatomy 0.000 description 6
- 108010046334 Urease Proteins 0.000 description 5
- 230000000694 effects Effects 0.000 description 5
- 230000007547 defect Effects 0.000 description 4
- 230000005484 gravity Effects 0.000 description 4
- 208000015181 infectious disease Diseases 0.000 description 4
- 238000005259 measurement Methods 0.000 description 4
- XSQUKJJJFZCRTK-NJFSPNSNSA-N UREA C 14 Chemical compound N[14C](N)=O XSQUKJJJFZCRTK-NJFSPNSNSA-N 0.000 description 3
- 210000004072 lung Anatomy 0.000 description 3
- 230000005855 radiation Effects 0.000 description 3
- 229950000184 urea c 14 Drugs 0.000 description 3
- 238000001574 biopsy Methods 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 238000007664 blowing Methods 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 210000001156 gastric mucosa Anatomy 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 238000011282 treatment Methods 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 241000750379 Erithacus akahige Species 0.000 description 1
- 241001522296 Erithacus rubecula Species 0.000 description 1
- 208000007882 Gastritis Diseases 0.000 description 1
- 206010019375 Helicobacter infections Diseases 0.000 description 1
- 208000005718 Stomach Neoplasms Diseases 0.000 description 1
- 208000007107 Stomach Ulcer Diseases 0.000 description 1
- XSQUKJJJFZCRTK-UHFFFAOYSA-N Urea Chemical compound NC(N)=O XSQUKJJJFZCRTK-UHFFFAOYSA-N 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 208000037976 chronic inflammation Diseases 0.000 description 1
- 230000006020 chronic inflammation Effects 0.000 description 1
- 238000003759 clinical diagnosis Methods 0.000 description 1
- 238000002405 diagnostic procedure Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 208000000718 duodenal ulcer Diseases 0.000 description 1
- 210000001198 duodenum Anatomy 0.000 description 1
- 206010017758 gastric cancer Diseases 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 201000005917 gastric ulcer Diseases 0.000 description 1
- 238000002575 gastroscopy Methods 0.000 description 1
- 238000002347 injection Methods 0.000 description 1
- 239000007924 injection Substances 0.000 description 1
- 238000011369 optimal treatment Methods 0.000 description 1
- 238000003752 polymerase chain reaction Methods 0.000 description 1
- 210000001187 pylorus Anatomy 0.000 description 1
- 230000002285 radioactive effect Effects 0.000 description 1
- 230000000241 respiratory effect Effects 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 201000011549 stomach cancer Diseases 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N23/00—Investigating or analysing materials by the use of wave or particle radiation, e.g. X-rays or neutrons, not covered by groups G01N3/00 – G01N17/00, G01N21/00 or G01N22/00
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/497—Physical analysis of biological material of gaseous biological material, e.g. breath
- G01N33/4977—Metabolic gas from microbes, cell cultures or plant tissues
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B10/00—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
- A61B2010/0083—Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements for taking gas samples
- A61B2010/0087—Breath samples
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- Biomedical Technology (AREA)
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- Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
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- Urology & Nephrology (AREA)
- Medical Informatics (AREA)
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- Sampling And Sample Adjustment (AREA)
Abstract
The invention relates to a helicobacter pylori detector, which effectively solves the problems that the existing device can not carry out mass centralized sampling and can not perfectly deal with cross infection and disinfection; the technical scheme includes that the air collecting box comprises a main box body, an air conveying pipe is fixed on one side of the main box body, a platform is arranged at the front end of the main box body, the upper end of the platform is in running fit with a collecting turntable, a plurality of groups of air collecting bags are uniformly distributed on the circumference of the upper end of the collecting turntable, the air conveying pipe is arranged in the main box body and is provided with two end parts including a first end part and a second end part, and the air collecting bags are provided with air inlets communicated with the first end part; a disinfectant storage barrel is arranged in the main box body in a sliding fit mode along the vertical direction, an opening is formed in the lower end of the disinfectant storage barrel, the second end portion of the disinfectant storage barrel is communicated with the opening, and when the disinfectant storage barrel moves, the two end portions of the end portion are closed; the invention can well complete the effective collection of the detection gas, and the adopted collection bag can not cause the gas to overflow and scatter, thereby well avoiding the cross infection and carrying out the effective disinfection operation in the detection process.
Description
Technical Field
The invention relates to the technical field of medical detection instruments, in particular to a helicobacter pylori detector.
Background
Helicobacter pylori was first isolated from a biopsy specimen of the gastric mucosa of a patient with chronic active gastritis by australian scholaren, robin Warren (j.robin Warren) and Barry marshall (Barry j.marshall) in 1983. Helicobacter pylori is a gram-negative and microaerophilic bacterium, and lives in various areas of the stomach and the duodenum, and can cause slight chronic inflammation of the gastric mucosa, or even gastric and duodenal ulcer and gastric cancer, people are the only natural hosts of the helicobacter pylori, the infection rate of people is high, and the infection rate of people all over the world is as high as 30-50%. Helicobacter pylori can cause many diseases, and thus is very important for its clinical diagnosis and treatment.
There are currently several commonly used modes of helicobacter pylori detection: 1. blood drawing test: the blood drawing method is used for detecting the helicobacter pylori antibody level in serum. The test results are positive because corresponding antibodies are produced in humans after infection with H.pylori, but it usually takes several months and a half. Therefore, when the detection is carried out at the initial stage of helicobacter pylori infection, false negative results often appear in the detection result, and the patient loses the optimal treatment opportunity.
2. Gastroscope sampling detection: when the patient needs gastroscopy, the 'lift' sampling can be carried out, and the biopsy sampling is carried out at the same time, so as to detect whether the helicobacter pylori exists. If positive, H.pylori infection can be diagnosed as positive. Culture and drug susceptibility testing may also be added from time to time in order to develop an appropriate treatment for the patient. After the gastroscope downsampling, polymerase chain reaction can be adopted, the sensitivity is high, and the result is reliable; the method can also be used for quickly detecting the urease, is simple and quick, and has unreliable results due to short observation time or certain factors.
3. Breath sampling test: the test has high sensitivity, high detection rate, high coincidence rate and no pain to patients. It is the most popular method for detecting helicobacter pylori in recent years.
Urea [14C ] breath test is a helicobacter pylori diagnostic method which is currently widely used internationally and domestically. Based on the respiratory detection principle of radioactive isotope C14, the characteristic that helicobacter pylori is rich in urease is utilized, and the micro-dose C-urea is orally taken by a detected person, so that the urease of the helicobacter pylori in the stomach catalyzes C-urea, and finally the C-urea is exhaled in a CO2 mode through the lung.
The helicobacter pylori detector is a nuclear radiation detector and is specially used for a 14C-urea breath test, and a collected breath sample is measured, so that whether helicobacter pylori is infected is diagnosed, but the breath card of the conventional helicobacter pylori detector cannot prevent air leakage, and a detection gas collected after the expiration is finished flows out through an exhalation port to cause certain detection deviation, and the conventional device cannot perform large-batch centralized sampling detection, so that cross infection and effective disinfection operation cannot be well treated in the detection process.
Due to the technical defects in the prior art, the technical problems to be solved urgently by the technical personnel in the field are solved; therefore, a helicobacter pylori detector is particularly important.
Disclosure of Invention
In order to overcome the defects of the prior art, the invention provides the helicobacter pylori detector which effectively solves the problems that the existing device cannot prevent air leakage, the detection air collected after expiration flows out through an expiration port to cause certain detection deviation, the existing device cannot carry out large-batch centralized sampling detection, and cross infection and effective disinfection operation cannot be well treated in the detection process.
The air delivery pipe collecting box comprises a main box body and is characterized in that an air delivery pipe extending into the main box body is fixedly arranged on one side of the main box body, a platform is arranged at the front end of the main box body, a collecting rotary disc is arranged at the upper end of the platform in a rotating fit manner, a plurality of groups of air collecting bags are uniformly distributed on the circumference of the upper end of the collecting rotary disc, the air delivery pipe is arranged at the end part with two openings in the main box body, the end part I and the end part II are included, and the air collecting bags are provided with air inlets communicated with the end part I;
the disinfection device is characterized in that a disinfection liquid bin is fixedly arranged in the main box body, a disinfection liquid storage barrel is arranged in the disinfection liquid bin in a sliding fit mode along the vertical direction, an opening is formed in the lower end of the disinfection liquid storage barrel, the second end portion is communicated with the opening, and when the disinfection liquid storage barrel moves, the second end portion is sealed.
Preferably, the lower end of the collecting turntable is coaxially fixed with grooved wheels, the grooved wheels are provided with radial grooves corresponding to the gas collecting bags in number one to one, the grooved wheels are driven by a rotating shaft arranged in a rotating fit with the platform, and driving pins matched with the radial grooves are fixed at the end part of the rotating shaft, so that the rotating shaft rotates for one circle, and the grooved wheels rotate to drive the gas collecting bags to be switched to the next one.
Preferably, the gas-supply pipe is arranged in the outside tip of the trunk body and is fixed with and holds the bucket, the tip activity of holding the bucket is provided with the filter tip, it is provided with through first spring fixed connection's grab handle to hold the bucket, the grab handle is fixed with first stay cord, the tip of first stay cord and the tip of antiseptic solution storage bucket are fixed.
Preferably, the rotating shaft is coaxially fixed with a one-way wheel, the outer ring of the one-way wheel is provided with a gear ring which is arranged in a matched manner with the platform in a rotating manner, ratchets are uniformly fixed on the inner ring of the gear ring, a pawl is arranged in a matched manner with the one-way wheel in a rotating manner, the pawl is fixedly connected with the one-way wheel through a second spring, and the ratchets are matched with the pawl, so that the one-way wheel is driven to rotate when the gear ring rotates in the forward direction, and the one-way wheel is driven to not rotate when the gear ring rotates in the reverse direction.
Preferably, the gear ring is engaged with a rack which is arranged in a sliding fit with the platform, and the rack is fixedly connected with the platform through a third spring.
Preferably, the initial state of the third spring is a stretched state, a second pull rope is fixed to one end of the rack, the end of the second pull rope is fixedly connected with the first pull rope, the spring elasticity of the third spring is smaller than that of the first spring, so that when the first spring is compressed, the third spring is restored to the original state, and the stroke of the first spring and the stroke of the third spring are set so that when the first spring is compressed to the limit, the rack drives the gear ring to rotate for one circle.
Preferably, the upper end of the platform is uniformly provided with U-shaped clamping plates which correspond to the gas collecting bags one by one, the end parts of the gas collecting bags are provided with T-shaped clamping ends, the clamping ends are clamped at the clamping plates to limit the gas collecting bags to move in the horizontal direction, and one part of the end part is integrally connected with a rubber port, so that when the gas collecting bags rotate to the position where the gas inlet is communicated with the end part, the rubber port is arranged in the gas inlet.
Preferably, the air inlet is provided with a one-way valve port, the one-way valve port comprises a fixed plate fixedly connected with the air collecting bag inside the air collecting bag, the fixed plate is connected with a blocking ball through a fourth spring, the blocking ball blocks the air inlet, so that air can only enter the air collecting bag from the outside, and the rear end of the air collecting bag is provided with a movable opening.
Preferably, the disinfectant tank is communicated with a liquid level display tank fixed on the outer wall of the main tank body, a transparent liquid level display panel is arranged in the vertical direction of the liquid level display tank, a semi-annular chuck is fixed on the outer portion of the main tank body, a clamping groove is formed in the chuck, a clamping column is integrally connected to the lower end of the holding barrel, and the clamping column can be clamped inside the clamping groove.
The invention has smart structure and strong practicability, and can effectively solve the following problems:
1. this device can be fine the completion to the effective collection that detects gas, and the collection bag of adoption can not lead to gaseous excessive scattered.
2. This device can be fine the completion to the effective collection that detects gas, can realize carrying out the sampling detection of concentrating in batches, and collection efficiency is high, can be fine avoid cross infection and carry out effectual disinfection operation in the in-process that detects.
3. The device can conveniently realize conversion and collection of different air collecting bags, is simple to operate, has high efficiency of collection and detection, and greatly saves manpower and material resources.
Drawings
Fig. 1 is a perspective view of the present invention.
Fig. 2 is a schematic front view of the present invention in use.
Fig. 3 is a side view of the present invention, schematically illustrated in fig. 1.
Fig. 4 is a side view of the present invention, schematically illustrated in fig. 2.
FIG. 5 is a schematic top view of the present invention.
Fig. 6 is a schematic cross-sectional view of the present invention, fig. 1.
Fig. 7 is a schematic cross-sectional view of the present invention, fig. 2.
FIG. 8 is a schematic view of the fitting relationship of the unidirectional wheel of the present invention.
FIG. 9 is a schematic view showing a piping arrangement of a gas pipe according to the present invention.
FIG. 10 is an enlarged view of the point A in FIG. 6 according to the present invention.
Reference numerals: 1. a main box body; 2. a gas delivery pipe; 2-1, end one; 2-2, end two; 3. a platform; 4. a collecting turntable; 5. an air collecting bag; 6. an air inlet; 7. an opening; 8. a grooved wheel; 9. a radial slot; 10. a drive pin; 11. holding the barrel; 12. a filter tip; 13. a first spring; 14. a handle; 15. a first pull cord; 16. a one-way wheel; 17. a gear ring; 18. a ratchet; 19. a pawl; 20. a second spring; 21. a rack; 22. a third spring; 23. a second pull cord; 24. clamping a plate; 25. clamping the end; 26. a rubber port; 27. a check valve port; 28. a fixing plate; 29. a fourth spring; 30. plugging the ball; 31. a movable opening; 32. a liquid level display bin; 33. a liquid level display panel; 34. a chuck; 35. a card slot; 36. and (5) clamping the column.
Detailed Description
The foregoing and other aspects, features and advantages of the invention will be apparent from the following more particular description of embodiments of the invention, as illustrated in the accompanying drawings in which reference is made to figures 1 to 10. The structural contents mentioned in the following embodiments are all referred to the attached drawings of the specification.
Exemplary embodiments of the present invention will be described below with reference to the accompanying drawings.
The helicobacter pylori detector disclosed by the first embodiment of the invention, please refer to fig. 1, and comprises a main box body 1, and is characterized in that a gas pipe 2 extending into the main box body 1 is fixedly arranged on one side of the main box body 1, a platform 3 is arranged at the front end of the main box body 1, a collection turntable 4 is arranged at the upper end of the platform 3 in a rotating fit manner, a plurality of groups of gas collecting bags 5 are uniformly distributed on the circumference of the upper end of the collection turntable 4, the gas pipe 2 is arranged at the end part with two openings in the main box body 1, and comprises the first end part 2-1 and the second end part 2-2, and the gas collecting bags 5 are provided with gas inlets 6 communicated with the first end part 2-1;
the disinfection device is characterized in that a disinfection liquid bin 4 is fixedly arranged inside the main box body 1, a disinfection liquid storage barrel 5 is arranged on the disinfection liquid bin 4 in a sliding fit mode along the vertical direction, an opening 7 is formed in the lower end of the disinfection liquid storage barrel 5, the second end portion 2-2 is communicated with the opening 7, and when the disinfection liquid storage barrel 5 moves, the end portion of the second end portion 2-2 is closed.
This example is of particular use, where C-urea is first administered orally in a micro-dose by the subject, such that if helicobacter pylori is present in the stomach of the subject, the urease of helicobacter pylori in the stomach catalyzes C-urea, and is finally exhaled through the lungs in the form of CO 2.
The device is used for exhaling and collecting crowds one by one, then the helicobacter pylori detector is a nuclear radiation detector (the prior art) to detect collected gas, the detector is specially used for a 14C-urea exhaling test, and an collected exhaled sample is measured, so that whether the helicobacter pylori is infected or not is diagnosed.
When the air collecting bag is used, a detector changes and uses the disposable filter tip to be connected with the outer end part of the air conveying pipe 2, as shown in figure 1, the disinfectant storage barrel 5 is controlled to move at the moment, the end part of the end part II 2-2 is closed, the disinfectant storage barrel 5 enters the disinfectant storage barrel 4 to supplement disinfectant synchronously, then the detector exhales through the filter tip, detected air is input into the air collecting bag 5 through the air conveying pipe 2, the air collecting bag 5 is closed, the end part II 2-2 is communicated with the opening 7 by controlling the disinfectant storage barrel 5 to move, the disinfectant in the disinfectant storage barrel 5 is injected into the air conveying pipe 2 through the opening 7 and the end part II 2-2, and then the disinfection of the inner part of the air conveying pipe 2 is completed.
After finishing collecting, collect carousel 4 through rotating for collection air pocket 5 converts to a new set of, accomplishes preliminary sampling to detecting crowd then, will collect 5 upper ends of air pocket and pass through the sampling crowd that the label mark corresponds, carries out the analysis through the collection air pocket 5 of helicobacter pylori detector system to collecting at last.
In the second embodiment, on the basis of the first embodiment, in order to enable the air collecting bag 5 of the device to better complete switching, please refer to fig. 2, a grooved wheel 8 is coaxially fixed at the lower end of the collecting turntable 4, the grooved wheel 8 is provided with radial grooves 9 corresponding to the air collecting bag 5 in number one by one, the grooved wheel 8 is driven by a rotating shaft 9 arranged in rotation fit with the platform 3, a driving pin 10 matched with the radial groove 9 is fixed at the end of the rotating shaft 9, so that the rotating shaft 9 rotates for one circle, and the grooved wheel 8 rotates to drive the air collecting bag 5 to switch to the next one.
When the sampling device is used specifically, firstly, after the sampling of expiration is completed for one sampling unit, the driving pin 10 is matched with the radial groove 9 through controlling the rotating shaft 9 to rotate for one circle, so that the rotating shaft 9 rotates for one circle, the grooved wheel 8 rotates to drive the air collecting bag 5 to be switched to the next one, and then, the primary sampling is completed for the detected crowd.
In a third embodiment, on the basis of the second embodiment, in order to better complete the control of the disinfectant storage tank 5, please refer to fig. 3 and 7, a holding tank 11 is fixed at an end portion of the gas pipe 2 disposed outside the main tank body 1, a filter 12 is movably disposed at an end portion of the holding tank 11, the holding tank 11 is provided with a grip 14 fixedly connected through a first spring 13, the grip 14 is fixed with a first pull rope 15, the first pull rope 15 in the device is fixed outside the gas pipe 2 as shown in fig. 7 through rope clamps uniformly distributed, and an end portion of the first pull rope 15 is fixed with an end portion of the disinfectant storage tank 5.
This embodiment is when specifically using, at first when the measurement personnel uses, the measurement personnel changes the outside end connection who uses disposable filter tip and gas-supply pipe 2, as shown in fig. 1, press grab handle 14 this moment, then first spring 13 compresses, then antiseptic solution storage bucket 5 realizes moving towards the lower extreme under self action of gravity, it should notice here that, antiseptic solution storage bucket 5 can be overcome to first spring 13's spring force, the action of gravity after the deposit is full of the antiseptic solution, control antiseptic solution storage bucket 5 removes, the tip of tip two 2-2 is sealed, it is antiseptic solution storage bucket 5 and gets into antiseptic solution storehouse 4 and supply the antiseptic solution to go on with it in step, then measurement personnel adopts the filter tip to exhale, then the gas that will detect passes through the inside of gas-supply pipe 2 input air collecting bag 5, then it is airtight to collect gas-collecting bag 5 after accomplishing.
When the collection finishes, loosen grab handle 14, under the effect of first spring 13 spring force, store bucket 5 through control antiseptic solution and remove to initial position towards the upper end, tip two 2-2's tip and opening 7 intercommunication, store 5 inside antiseptic solution of bucket through opening 7 with antiseptic solution, tip two 2-2 pours into the inside of gas-supply pipe 2 into, then accomplish the disinfection to gas-supply pipe 2 inside, the user arranges the outside tip of gas-supply pipe 2 in the lower extreme this moment, discharge the antiseptic solution to the container of collecting the waste liquid in, accomplish the disinfection to gas-supply pipe 2, avoid appearing the drawback of next detection person false retrieval.
In an embodiment four, on the basis of the embodiment three, in order to enable the device to work better, please refer to fig. 8, a one-way wheel 16 is coaxially fixed on the rotating shaft 9, a gear ring 17 which is arranged in a rotationally matched manner with the platform 3 is arranged on an outer ring of the one-way wheel 16, ratchets 18 are uniformly fixed on an inner ring of the gear ring 17, a pawl 19 is arranged in a rotationally matched manner on the one-way wheel 16, the pawl 19 is fixedly connected with the one-way wheel 16 through a second spring 20, the ratchets 18 are matched with the pawl 19, so that the one-way wheel 16 is driven to rotate when the gear ring 17 rotates forward, and the one-way wheel 16 is driven to not rotate when the gear ring 17 rotates reversely.
This embodiment is when specifically using, at first when the unit to a sampling accomplishes the expiration sampling back, through control during gear ring 17 forward rotation round, drive one-way wheel 16 rotates the round, and pivot 9 rotates the round, and drive round 10 cooperation radial groove 9 this moment makes pivot 9 rotates the round, sheave 8 rotates the drive air collection bag 5 switches to next, accomplishes preliminary sampling to detecting crowd then.
And then the gear ring 17 is controlled to rotate reversely for one circle to return to the initial state, the one-way wheel 16 does not rotate, and then the switching of the air collecting bag 5 is completed by repeated work.
In the fifth embodiment, on the basis of the fourth embodiment, in order to make the rotation of the gear ring 17 more convenient and reasonable, please refer to fig. 8, the gear ring 17 is engaged with a rack 21 disposed in sliding fit with the platform 3, and the rack 21 is fixedly connected with the platform 3 through a third spring 22.
In a sixth embodiment, in addition to the fifth embodiment, the initial state of the third spring 22 is a stretched state, a second rope 23 is fixed to one end of the rack 21, an end of the second rope 23 is fixedly connected to the first rope 15, and a spring force of the third spring 22 is smaller than a spring force of the first spring 13, so that when the first spring 13 is compressed, the third spring 22 is restored to its original state, and when the first spring 13 is compressed to a limit, the stroke of the first spring 13 and the stroke of the third spring 22 are set, so that the rack 21 drives the gear ring 17 to rotate by one turn.
When the embodiment is used specifically, firstly when a sampling unit is subjected to breath sampling, as shown in fig. 1, the grab handle 14 is pressed at this time, then the first spring 13 is compressed, at this time the third spring 22 is restored to the original state, then the rack 21 is moved through the elastic action of the third spring 22, the rack 21 is driven to rotate with the gear ring 17 engaged with the rack 21 when moving, when the first spring 13 is compressed to the limit, the gear ring 17 is controlled to rotate forwards for one circle, the one-way wheel 16 is driven to rotate for one circle, the rotating shaft 9 rotates for one circle, the driving pin 10 at this time is matched with the radial groove 9, so that the rotating shaft 9 rotates for one circle, the grooved wheel 8 rotates to drive the air collecting bag 5 to be switched to the next one, and then preliminary sampling is completed for the detected crowd.
After the collection finishes, loosen the grab handle 14 this moment, then drive the second stay cord 23 under the effect of the spring restoring force of first spring 13 and remove pulling rack 21 and resume initial state, then drive gear circle 17 and reverse the rotation idle running, when gear circle 17 reverse rotation round resumes initial state, one-way wheel 16 does not rotate, and then the switching of air collecting bag 5 has been accomplished in the repeated work.
Seventh embodiment, on the basis of the first embodiment, in order to ensure the stable performance of the air collecting bag 5 in the device, please refer to fig. 4 and 10, U-shaped clamping plates 24 corresponding to the air collecting bag 5 one by one are uniformly arranged at the upper end of the platform 3, a T-shaped clamping end 25 is arranged at an end of the air collecting bag 5, the clamping end 25 is clamped at the clamping plate 24 to limit the air collecting bag 5 to move in the horizontal direction, and a rubber port 26 is integrally connected to a position 2-1 of the end, so that when the air collecting bag 5 rotates until the air inlet 6 is communicated with the end 2-1, the rubber port 26 is arranged inside the air inlet 6.
In an eighth embodiment, on the basis of the seventh embodiment, the exhalation card of the conventional helicobacter pylori detector cannot prevent air leakage, and when the pylorus helicobacter pylori detector exhales, air flows out through the exhalation port to cause a certain detection deviation, in order to solve the problem, referring to fig. 4 and 10, a one-way valve port 27 is arranged at the position where the air inlet 6 is arranged, the one-way valve port 27 includes a fixing plate 28 fixedly connected with the air collection bag 5 inside the air collection bag 5, the fixing plate 28 is connected with a blocking ball 30 through a fourth spring 29, the blocking ball 30 blocks the air inlet 6, so that air can only enter the air collection bag 5 from the outside, and a movable opening 31 is arranged at the rear end of the air collection bag 5.
When the gas collection bag 5 is switched to the next one in specific use, the rubber port 26 at this time is placed inside the gas inlet 6, then the detection personnel blows gas, the gas at this time can apply pressure to the one-way valve port 27, the blocking ball 30 extrudes the fourth spring 29, the one-way valve port 27 is opened, the gas can enter the gas collection bag 5, so that the gas collection bag 5 is filled with the gas to be detected, when the detection personnel stops blowing gas, the pressure of the one-way valve port 27 in the gas collection bag 5 at this time is lost, then the fourth spring 29 is restored to the initial state due to the action of spring elasticity, the gas inside the gas collection bag 5 cannot leak due to the closing of the one-way valve port 27, and the defect that the gas in the gas collection bag overflows in the prior art cannot exist.
In a ninth embodiment, on the basis of the third embodiment, please refer to fig. 7, in order to ensure the stability of the liquid level of the disinfectant tank 4 and the more convenient filling, please refer to fig. 4, the disinfectant tank 4 is communicated with a liquid level display tank 32 fixed to the outer wall of the main tank 1, a transparent liquid level display plate 33 is vertically arranged on the liquid level display tank 32, a semi-annular chuck 34 is fixed to the outside of the main tank 1, the chuck 34 is provided with a clamping groove 35, the lower end of the holding barrel 11 is integrally connected with a clamping column 36, and the clamping column 36 can be clamped inside the clamping groove 35.
In a particular use of the invention, C-urea is first administered orally in a micro-dose by the subject, if helicobacter pylori is present in the stomach of the subject, so that the urease of helicobacter pylori in the stomach catalyzes C-urea, and is finally exhaled through the lungs in the form of CO 2.
The device is used for exhaling and collecting crowds one by one, then the helicobacter pylori detector is a nuclear radiation detector (the prior art) to detect collected gas, the detector is specially used for a 14C-urea exhaling test, and an collected exhaled sample is measured, so that whether the helicobacter pylori is infected or not is diagnosed.
Firstly when exhaling the sample to the unit of a sampling, as shown in figure 1, the outside end connection of disposable filter tip and gas-supply pipe 2 is used to the measurement personnel change, press grab handle 14 this moment, then first spring 13 compresses, then antiseptic solution storage bucket 5 realizes moving towards the lower extreme under self action of gravity, it should be noted here that, the spring force of first spring 13 can overcome the action of gravity of antiseptic solution storage bucket 5 after the deposit is full of antiseptic solution, control antiseptic solution storage bucket 5 and remove, the tip of tip two 2-2 is sealed, go on with it in step, antiseptic solution storage bucket 5 gets into antiseptic solution storehouse 4 and replenishes antiseptic solution to its inside.
At the moment, in synchronization with the above, the third spring 22 is restored, then the rack 21 is moved by the elastic force of the third spring 22, the rack 21 drives the gear ring 17 engaged with the rack to rotate when moving, when the first spring 13 is compressed to the limit, the one-way wheel 16 is driven to rotate for one circle by controlling the gear ring 17 to rotate for one circle in the forward direction, the rotating shaft 9 rotates for one circle, the driving pin 10 at this time cooperates with the radial groove 9, so that the rotating shaft 9 rotates for one circle, the grooved wheel 8 rotates to drive the air collecting bag 5 to switch to the next, the rubber port 26 at this time is placed inside the air inlet 6, then the tester blows air, at this time, the air applies pressure to the one-way valve port 27, the blocking ball 30 extrudes the fourth spring 29, the one-way valve port 27 is opened, the air enters the air collecting bag 5, and the air collecting bag 5 is filled with the air to be tested, when the tester stops blowing, the pressure of the one-way valve port 27 in the gas collection bag 5 is lost, then the fourth spring 29 is restored to the initial state due to the action of the spring force, the gas in the gas collection bag 5 cannot leak out due to the closing of the one-way valve port 27, and the defect that the gas in the gas collection bag overflows in the prior art cannot exist.
And then completing preliminary sampling on the detected crowd.
After the collection finishes, loosen the grab handle 14 this moment, then drive the second stay cord 23 under the effect of the spring restoring force of first spring 13 and remove pulling rack 21 and resume initial state, then drive gear circle 17 and reverse the rotation idle running, when gear circle 17 reverse rotation round resumes initial state, one-way wheel 16 does not rotate, and then the switching of air collecting bag 5 has been accomplished in the repeated work.
Go on with it in step, under the effect of first spring 13 spring force, store bucket 5 through control antiseptic solution and remove to initial position towards the upper end, tip and opening 7 intercommunication of two 2-2 of tip, store 5 inside antiseptic solutions of bucket through opening 7 with antiseptic solution, the inside of tip two 2-2 injection gas-supply pipe 2, then accomplish the disinfection to the inside of gas-supply pipe 2, the user of this moment arranges the outside tip of gas-supply pipe 2 in the lower extreme, discharge the antiseptic solution to the container of collecting the waste liquid in, accomplish the disinfection to gas-supply pipe 2, avoid appearing the drawback of next detector false retrieval.
The upper end of the gas collecting bag 5 is marked with corresponding sampling people through a label, and finally the collected gas collecting bag 5 is analyzed through a helicobacter pylori detector system.
The invention has smart structure and strong practicability, and can effectively solve the following problems:
4. this device can be fine the completion to the effective collection that detects gas, and the collection bag of adoption can not lead to gaseous excessive scattered.
5. This device can be fine the completion to the effective collection that detects gas, can realize carrying out the sampling detection of concentrating in batches, and collection efficiency is high, can be fine avoid cross infection and carry out effectual disinfection operation in the in-process that detects.
The device can conveniently realize conversion and collection of different air collecting bags, is simple to operate, has high efficiency of collection and detection, and greatly saves manpower and material resources.
Claims (9)
1. A helicobacter pylori detector comprises a main box body (1), and is characterized in that a gas conveying pipe (2) extending into the main box body (1) is fixedly arranged on one side of the main box body (1), a platform (3) is arranged at the front end of the main box body (1), a collecting turntable (4) is arranged at the upper end of the platform (3) in a rotating fit manner, a plurality of groups of gas collecting bags (5) are uniformly distributed on the circumference of the upper end of the collecting turntable (4), the gas conveying pipe (2) is arranged in the main box body (1) and is provided with two open end parts, including a first end part (2-1) and a second end part (2-2), and the gas collecting bags (5) are provided with gas inlets (6) communicated with the first end part (2-1);
the disinfection device is characterized in that a disinfection liquid bin (4) is fixedly arranged inside the main box body (1), the disinfection liquid bin (4) is provided with a disinfection liquid storage barrel (5) in a sliding fit mode along the vertical direction, an opening (7) is formed in the lower end of the disinfection liquid storage barrel (5), two end portions (2-2) are communicated with the opening (7), and when the disinfection liquid storage barrel (5) moves, the end portions of the two end portions (2-2) are sealed.
2. The helicobacter pylori detector according to claim 1, wherein a grooved wheel (8) is coaxially fixed to the lower end of the collecting turntable (4), the grooved wheel (8) is provided with radial grooves (9) corresponding to the air collecting bags (5) in number one by one, the grooved wheel (8) is driven by a rotating shaft (9) in rotation fit with the platform (3), a driving pin (10) matched with the radial grooves (9) is fixed to the end of the rotating shaft (9), so that the rotating shaft (9) rotates for one circle, and the grooved wheel (8) rotates to drive the air collecting bags (5) to be switched to the next one.
3. The helicobacter pylori detector of claim 2, characterized in that the end portion of the gas pipe (2) arranged outside the main tank body (1) is fixed with a holding barrel (11), the end portion of the holding barrel (11) is movably provided with a filter tip (12), the holding barrel (11) is provided with a grab handle (14) fixedly connected with a first spring (13), the grab handle (14) is fixed with a first pull rope (15), and the end portion of the first pull rope (15) is fixed with the end portion of the disinfectant storage barrel (5).
4. The helicobacter pylori detector according to claim 3, wherein a one-way wheel (16) is coaxially fixed to the rotating shaft (9), a gear ring (17) which is rotatably fitted to the platform (3) is arranged on an outer ring of the one-way wheel (16), ratchets (18) are uniformly fixed to an inner ring of the gear ring (17), a pawl (19) is rotatably fitted to the one-way wheel (16), the pawl (19) and the one-way wheel (16) are fixedly connected through a second spring (20), and the ratchets (18) are fitted to the pawls (19), so that the one-way wheel (16) is driven to rotate when the gear ring (17) rotates forward, and the one-way wheel (16) is driven to not rotate when the gear ring (17) rotates reversely.
5. The helicobacter pylori detector according to claim 4, wherein the gear ring (17) is engaged with a rack (21) which is arranged in a sliding fit with the platform (3), and the rack (21) is fixedly connected with the platform (3) through a third spring (22).
6. The helicobacter pylori detector according to claim 5, wherein the third spring (22) is in a stretched state at an initial state, a second pull rope (23) is fixed to one end of the rack (21), the end of the second pull rope (23) is fixedly connected with the first pull rope (15), the spring force of the third spring (22) is smaller than that of the first spring (13), so that when the first spring (13) is compressed, the third spring (22) is restored to the original state, and the stroke of the first spring (13) and the stroke of the third spring (22) are set so that when the first spring (13) is compressed to the limit, the rack (21) drives the gear ring (17) to rotate for one circle.
7. The helicobacter pylori detector according to claim 1, wherein U-shaped snap-gauge plates (24) corresponding to the air collecting bag (5) one by one are uniformly arranged at the upper end of the platform (3), a T-shaped clamping end (25) is arranged at the end of the air collecting bag (5), the clamping end (25) is clamped at the snap-gauge plate (24) to limit the air collecting bag (5) to move in the horizontal direction, and a rubber port (26) is integrally connected to the first end (2-1) to ensure that the rubber port (26) is arranged in the air inlet (6) when the air collecting bag (5) rotates until the air inlet (6) is communicated with the first end (2-1).
8. Helicobacter pylori detector according to claim 7, characterized in that the air inlet (6) is provided with a one-way valve port (27), the one-way valve port (27) comprises a fixing plate (28) fixedly connected with the air collecting bag (5) inside the air collecting bag (5), the fixing plate (28) is connected with a blocking ball (30) via a fourth spring (29), the blocking ball (30) blocks the air inlet (6) so that air can only enter the air collecting bag (5) from the outside, and the rear end of the air collecting bag (5) is provided with a movable opening (31).
9. The helicobacter pylori detector according to claim 3, wherein the sterilizing liquid chamber (4) is communicated with a liquid level display chamber (32) fixed to the outer wall of the main tank body (1), a transparent liquid level display plate (33) is arranged in the vertical direction of the liquid level display chamber (32), a semi-annular chuck (34) is fixed to the outside of the main tank body (1), a clamping groove (35) is formed in the chuck (34), a clamping column (36) is integrally connected to the lower end of the holding barrel (11), and the clamping column (36) can be clamped in the clamping groove (35).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202210279794.4A CN114544923A (en) | 2022-03-22 | 2022-03-22 | Helicobacter pylori detector |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202210279794.4A CN114544923A (en) | 2022-03-22 | 2022-03-22 | Helicobacter pylori detector |
Publications (1)
Publication Number | Publication Date |
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CN114544923A true CN114544923A (en) | 2022-05-27 |
Family
ID=81666463
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
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CN202210279794.4A Withdrawn CN114544923A (en) | 2022-03-22 | 2022-03-22 | Helicobacter pylori detector |
Country Status (1)
Country | Link |
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CN (1) | CN114544923A (en) |
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2022
- 2022-03-22 CN CN202210279794.4A patent/CN114544923A/en not_active Withdrawn
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