CN114466597B - Aerosol-generating tobacco-containing compositions comprising medium chain triglycerides - Google Patents

Aerosol-generating tobacco-containing compositions comprising medium chain triglycerides Download PDF

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CN114466597B
CN114466597B CN202080068104.XA CN202080068104A CN114466597B CN 114466597 B CN114466597 B CN 114466597B CN 202080068104 A CN202080068104 A CN 202080068104A CN 114466597 B CN114466597 B CN 114466597B
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aerosol
tobacco
composition according
lipid
generating
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CN114466597A (en
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D.利克费尔德
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JT International SA
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    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10Chemical features of tobacco products or tobacco substitutes
    • A24B15/12Chemical features of tobacco products or tobacco substitutes of reconstituted tobacco
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18Treatment of tobacco products or tobacco substitutes
    • A24B15/28Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B13/00Tobacco for pipes, for cigars, e.g. cigar inserts, or for cigarettes; Chewing tobacco; Snuff
    • A24B13/02Flakes or shreds of tobacco
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10Chemical features of tobacco products or tobacco substitutes
    • A24B15/12Chemical features of tobacco products or tobacco substitutes of reconstituted tobacco
    • A24B15/14Chemical features of tobacco products or tobacco substitutes of reconstituted tobacco made of tobacco and a binding agent not derived from tobacco
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10Chemical features of tobacco products or tobacco substitutes
    • A24B15/16Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/10Chemical features of tobacco products or tobacco substitutes
    • A24B15/16Chemical features of tobacco products or tobacco substitutes of tobacco substitutes
    • A24B15/167Chemical features of tobacco products or tobacco substitutes of tobacco substitutes in liquid or vaporisable form, e.g. liquid compositions for electronic cigarettes
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18Treatment of tobacco products or tobacco substitutes
    • A24B15/24Treatment of tobacco products or tobacco substitutes by extraction; Tobacco extracts
    • A24B15/241Extraction of specific substances
    • A24B15/243Nicotine
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18Treatment of tobacco products or tobacco substitutes
    • A24B15/28Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/287Treatment of tobacco products or tobacco substitutes by chemical substances by inorganic substances only
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18Treatment of tobacco products or tobacco substitutes
    • A24B15/28Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/302Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by natural substances obtained from animals or plants
    • A24B15/303Plant extracts other than tobacco
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18Treatment of tobacco products or tobacco substitutes
    • A24B15/28Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/30Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances
    • A24B15/32Treatment of tobacco products or tobacco substitutes by chemical substances by organic substances by acyclic compounds
    • AHUMAN NECESSITIES
    • A24TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24BMANUFACTURE OR PREPARATION OF TOBACCO FOR SMOKING OR CHEWING; TOBACCO; SNUFF
    • A24B15/00Chemical features or treatment of tobacco; Tobacco substitutes, e.g. in liquid form
    • A24B15/18Treatment of tobacco products or tobacco substitutes
    • A24B15/28Treatment of tobacco products or tobacco substitutes by chemical substances
    • A24B15/42Treatment of tobacco products or tobacco substitutes by chemical substances by organic and inorganic substances

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Toxicology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Agronomy & Crop Science (AREA)
  • Botany (AREA)
  • Inorganic Chemistry (AREA)
  • Manufacture Of Tobacco Products (AREA)

Abstract

The present invention relates to an aerosol-generating tobacco-containing composition, preferably provided in the form of a foam or mousse, and an aerosol-generating article comprising said composition, wherein the composition comprises a particulate tobacco material and a lipid, wherein the lipid is a medium chain triglyceride in a ratio to the tobacco-containing material of between 1.

Description

Aerosol-generating tobacco-containing compositions comprising medium chain triglycerides
Technical Field
The present invention relates to aerosol-generating tobacco-containing compositions comprising tobacco material, comprising an aerosol-generating material and medium chain triglycerides, and aerosol-generating articles, in particular heated non-combustible smoking articles, comprising such compositions.
Background
A number of prior art documents relating to aerosol generating articles and devices therefor have disclosed the use of such articles as new forms of smoking. Such devices include, for example, electrically heated aerosol-generating devices in which an aerosol is generated by transferring heat from a heating element of the aerosol-generating device to an aerosol-generating substrate or material.
Homogenized tobacco material is commonly used to produce tobacco products. Parts of tobacco plants that are less suitable for producing cut filler (such as tobacco stems or tobacco dust) are typically materials used for homogenized tobacco material. Examples of common forms of homogenized tobacco material are, for example, powder form, reconstituted tobacco sheet and cast leaf.
It has been reported that in heated non-combustible aerosol generating articles, the aerosol-forming substrate is heated at a relatively low temperature (e.g. below 350 ℃) to avoid combustion thereof. A charge of inhalable aerosol may then be released from the aerosol generating article.
The released aerosol originates from an aerosol former incorporated into the tobacco material, which may be particulate or particulate. In order to be released, these aerosol-formers have to migrate from within the body of the homogenized tobacco material to the surface of the homogenized tobacco material. During this process, other volatile compounds, such as nicotine, migrate outwardly from the body of homogenized tobacco material in a similar manner and are eventually released in the form of an aerosol charge.
Document WO 2017/077112 A1 relates to a homogenized tobacco material comprising tobacco and a lipid having a melting point between 50 ℃ and 150 ℃. It is disclosed therein that a homogenized tobacco material comprising a meltable lipid component advantageously allows the use of less tobacco while providing an equivalent nicotine or aerosol yield. Furthermore, the inclusion of the meltable lipid component also allows aerosol former and other volatile compounds within the homogenized tobacco material to migrate to the surface area of the tobacco material. However, these advantages are at the cost of not completely avoiding off-flavors and off-tastes generated by the meltable lipid component.
Accordingly, it would be desirable to provide an aerosol generating tobacco-containing material for use in aerosol generating articles that does not impart an unpleasant odor or taste to the consumer. Furthermore, it is particularly desirable to improve the delivery of volatile compounds, including nicotine, and particularly when operating at lower temperatures. Furthermore, it would be desirable to provide an aerosol-generating article of homogenized tobacco material having a novel form, which article is suitable for use in the delivery of volatile compounds.
Disclosure of Invention
The inventors of the present invention have found a solution to the above problem by means of an aerosol-generating tobacco-containing composition as defined in the claims.
Accordingly, a first aspect of the invention provides an aerosol-generating tobacco-containing composition provided in the form of a foam or mousse, wherein the composition comprises a particulate tobacco material and a lipid, wherein the lipid is a medium chain triglyceride, the ratio of medium chain triglyceride to tobacco-containing material being between 1.
Accordingly, a second aspect of the present invention provides an aerosol-generating article comprising an aerosol-generating tobacco-containing composition provided in the form of a foam or mousse according to the invention.
Accordingly, a third aspect of the present invention provides a method of preparing an aerosol-generating tobacco-containing foam or mousse, comprising the steps of: (a) Mixing the aerosol former, foam former and optionally solvent under heating; (b) Aerating the mixture with gas or air at room temperature for at least 5 minutes; (c) Adding a tobacco-containing component and/or an inhalant to the mixture; (d) optionally aerating the mixture with gas or air; (e) Adding medium chain triglycerides to the mixture, wherein the ratio of medium chain triglycerides to tobacco-containing material is between 1; (f) Aerating the mixture with gas or air at room temperature for at least 5 minutes; (g) adding a foam stabilizer.
The present inventors have found that aerosol-generating tobacco-containing compositions, when provided in the form of a foam or mousse, more significantly and unexpectedly solve the off-taste and off-taste problems of homogenized tobacco material when using lipids. The inventors found that Medium Chain Triglycerides (MCT) were a better choice to mix with homogenized tobacco material than lipids, as MCT is highly evaluated for its clean organoleptic qualities. They are odourless and tasteless; therefore, they do not provide any off-flavour to the product.
In addition, the inventors found that when the ratio of MCT to homogenized tobacco material on a dry weight basis was between 1. Interestingly, when the dry weight basis MCT to homogenized tobacco material ratio is outside of these ranges (i.e. greater than 1.
For example, when MCT is less than 20 wt% of the total weight on a dry weight basis, these effects (porosity and bulk of the composition and stronger tobacco flavor, e.g., when in the form of a mousse or foam) are not optimal regardless of the final amount of tobacco-containing material because less volatile compounds are released with the charge of aerosol. In the inventionThe stronger tobacco flavor and aroma obtained in (a) is due to MCT. MCT is widely used in the flavor industry because of its excellent organoleptic qualities and solvent ability. Further, MCT is also excellent in flavor extraction. The most likely reason is that the higher the percentage of MCT (i.e. the ratio of MCT to tobacco-containing material is at least 1. Furthermore, the inventors have found that the aerosol generating tobacco-containing compositions claimed in the present invention typically have a pore size of less than 2nm and that the composition has a general bulk in the range of 1-3g/cm 3 In the meantime. Because of these characteristics of the compositions, aerosol-generating articles comprising these compositions are immediately distinguishable from other articles, and are therefore a preferred choice.
In a particularly preferred embodiment, the ratio of medium chain triglycerides to tobacco containing material is 1. This embodiment is most preferred because the delivery rate of volatile compounds such as nicotine was found to be highest compared to all other samples with different ratios. The inventors of the present invention have found that when the ratio of MCT to tobacco-containing material on a dry weight basis is 1.
In a particularly preferred embodiment, the composition is provided in the form of a foam or mousse. When the aerosol generating material is provided in the form of a foam or mousse, the volume of the porous microstructure of the foam is enhanced by the use of MCT, in comparison to other forms in which the material is provided, for example, in the form of reconstituted tobacco sheets or powders, especially when the ratio of MCT to tobacco containing material on a dry weight basis is 1. In this regard, it is disclosed herein that foam formers and foam stabilizers participate in the formation of foam and the maintenance of the foam microstructure.
To this end, it is reiterated that the present invention in the form of a foam or mousse can be applied to all of the other embodiments discussed herein.
According to one embodiment, in each step, the mixture is aerated with heated gas or air at between 35 ℃ and 50 ℃ for at least 10 minutes. Such elevated temperatures increase the texture, consistency and nicotine delivery of the aerosol-generating tobacco-containing foam or mousse compared to, for example, products made from powder form. Furthermore, the volume of the porous microstructure of the foam can be increased by using MCT at such temperatures.
In another preferred embodiment, the aerosol-generating tobacco containing composition comprising medium chain triglycerides is aerated at room temperature for at least 5 minutes, preferably at least 10 minutes. The aeration step referred to herein increases the volume of the porous microstructure of the aerosol generating material of the present invention.
According to one embodiment, the particle size of the particulate tobacco material is less than 100 μm, preferably less than 90 μm, 80 μm, 70 μm, 60 μm or 50 μm, more preferably between 40 μm and 90 μm. The aerosol generating material of the present invention, which consists essentially of tobacco material, will have a uniform tobacco particle size when the particle size of the tobacco-containing material is provided to be less than 100 μm. Furthermore, due to the small particle size, the amount of surface area per unit volume of the homogenized tobacco material is also increased. Volatile compounds from the aerosol generating material can thus be released into the aerosol easily and more efficiently.
According to another embodiment, the lipid is derived from palm kernel oil or coconut oil.
In yet another embodiment, the lipid consists of caprylic acid (C8: 0), capric acid (C10: 0) and/or preferably lauric acid (C12: 0).
In another preferred embodiment, more than 50wt. -%, preferably more than 60wt. -% or 66wt. -% of the lipid is MCT octanoic acid (C8: 0), based on the total weight of the lipid.
According to another embodiment, the composition further comprises maltodextrin gum arabic, silica, and/or sunflower lecithin.
In a further embodiment, the composition comprises any of a propellant, an aerosol former, a foam stabilizer and/or a foam former.
According to a further embodiment, the composition comprises an aerosol former in a proportion of 10-80wt. -%, preferably 30-70wt. -%, based on the weight of the aerosol generating material.
In reference to a given value, "about" or "approximately" is intended to include the value within 10% of the stated value. All values given in this disclosure should be understood to be supplemented by the word "about" unless the context clearly dictates otherwise.
The indefinite article "a" or "an" does not exclude a plurality and should therefore be taken broadly.
Unless defined otherwise, technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs.
The tobacco-containing material can be any compound, mixture, particulate matter, and/or solution that contains and/or carries tobacco components, either artificially contained or naturally contained in tobacco, such as tobacco, tobacco particles, tobacco flavors, and/or nicotine. In contrast, an example of a non-tobacco specific flavoring agent that is added manually is menthol.
As used herein, the term "aerosol-generating article" refers to an aerosol-generating article for generating an aerosol comprising an aerosol-generating material intended to be heated, rather than combusted, to release volatile compounds that can form an aerosol.
As used herein, the term "aerosol generating material" refers to a material that is capable of releasing volatile compounds that can form an aerosol when heated. The aerosol generated from the aerosol generating material of the aerosol generating articles described herein may be visible or invisible, and may comprise a vapour (e.g. particles of a substance in a gaseous state, typically a liquid or solid at room temperature) as well as droplets of a gas and condensed vapour.
As used herein, the term "medium chain triglycerides" is used to define an oil comprising one or more triglycerides, each triglyceride having two or three fatty acid chains with a chain length between 6 and 12 carbon atoms. Thus, the fatty acid chains may comprise one or more of caproic acid (C6), caprylic acid (C8), capric acid (C10) and lauric acid (C12). These may be present in the medium chain triglyceride oil in any combination and in any relative amount, provided that the desired properties of the medium chain triglyceride oil are obtained. For each triglyceride in the medium chain triglyceride oil, the three fatty acid chains may be of the same or different length from each other, provided that at least two of the fatty acid chains have a chain length between 6 and 12 carbon atoms. The three fatty acid chains may be the same for each triglyceride, or two or more of the fatty acid chains may be different from each other. Triglycerides may be saturated or unsaturated, respectively.
As used herein, the term "homogenized tobacco material" includes any tobacco material formed by agglomeration of particles of tobacco material (together or in admixture with other plant materials). For example, the homogenized tobacco material may be provided in particulate (powder) form, or it may be provided as a sheet or web of homogenized tobacco material by agglomerating particulate tobacco material obtained by grinding or otherwise powdering one or both of tobacco leaf lamina and tobacco leaf stem. In addition, the homogenized tobacco material may contain small amounts of one or more of tobacco dust, tobacco fines, and other particulate tobacco by-products formed during handling, and transportation of the tobacco. The homogenized tobacco material may also be provided in small particles, for example less than 100 μm, as claimed in the present invention, and subsequently used to constitute an aerosol generating material, which may be in the form of a foam or mousse.
The aerosol former can be any compound, mixture, and/or solution capable of forming an aerosol, for example, when heated and/or mixed with a tobacco-containing agent. Well-known examples include humectants such as glycerol and propylene glycol, other alcohols such as ethanol, and the like.
Open-cell foam as used herein is understood to be formed by a plurality of interconnected pores (formed by the cooperation of a structural material derived from a foam forming agent with interacting components such as foam stabilisers, solid components such as tobacco particles and some solvents and the like) capable of containing a fluid, in particular a mixture of a humectant/liquid aerosol-forming substrate and air, wherein at least a majority (e.g. more than 50% by volume) of the pores in the foam are fluidly connected to one another, as opposed to closed-cell foam, wherein a majority of the pores form discrete pockets, each of which is fully encapsulated by the pore-forming material, so as to substantially prevent free passage of fluid between the pores. It is presently believed that the mousse formed as described herein is to a large extent an open cell mousse, in that upon cooling or heating the aerosol generating material comprising MCT, vapour is released from the mousse, substantially all of the humectant appears to be released based on measuring the weight of the mousse portion before and after heating, which is not readily explained if the humectant is unable to travel through adjacent pores to the surface of the mousse portion. However, other explanations cannot be completely excluded — for example, the closed pores may be opened by rupturing the closed pore walls due to the pressure of the vaporized gas, or the like.
As mentioned in the present invention, an electronic cigarette (e-cigarette) or similar device (like an e-pipe heated non-combustible device) is not particularly limited and may be used to provide aerosol to the user for inhalation. According to some embodiments, it may include a mouthpiece, a heater, a receiving portion (e.g., a pod), a wand, a bladder, and a housing.
As used herein, the term "melting point" refers to the clearing point or the complete melting point of the medium chain triglycerides. This corresponds to the temperature in degrees celsius at which the oil is completely liquid and completely transparent, with no solid particles remaining. Many methods known in the art can be used to measure the clear point melting point of an oil, such as capillary techniques or Stuart SMP50 melting point devices.
As used herein, wt. -% is to be understood as a weight percentage based on the total weight of dry matter, unless explicitly stated otherwise. In the present disclosure, all amounts are given in wt. -% unless explicitly stated otherwise or apparent from the context. Furthermore, in the present disclosure, all amounts given in wt. -% add up to 100wt. -%. Thus, the weight percent is calculated by dividing the mass of each component by, for example, the total mass of the foam, unless otherwise indicated or clear from the context.
Detailed Description
The present invention relates to aerosol-generating tobacco-containing compositions comprising lipids in the form of Medium Chain Triglyceride (MCT) oil. The composition may be provided in many forms, such as one or more sheets of homogenized tobacco material, or in the form of a foam or mousse or powder, wherein the dry basis ratio between MCT and tobacco-containing material is between 1. It is emphasized here that the invention is not limited to these two forms, but other forms, such as powder form, gel or coating of the aerosol generating material of the invention on a carrier are also possible.
Because the melting point of MCT is around 20℃, the MCT discussed in this invention is always present in a completely liquid form at room temperature (e.g., 22℃. To 24℃.). Thus, the homogenized tobacco material comprises MCT oil in liquid form dispersed in a matrix (solid or semi-solid, such as a foam or gel) of the tobacco-containing material.
MCTs for use in the present invention are commercially available. For example, it is available from the company Sensory Effects (product ID: richmix 5025IP (175755)), and comprises a powdered creamer of 52% fatty MCT oil made from palm-derived palm kernel and/or coconut-based fatty acids. The product also contains maltodextrin and gum arabic, silica and sunflower lecithin according to the product description. The MCT has a melting point significantly below 20 ℃, wherein the ratio of MCT C6: C8: C10: C12 is about 1. In other words, the MCTs used in this invention have negligible C6 and C12 content.
To this end, it is reiterated that any commercially available MCT is suitable for use in the present invention, provided that the commercially available product meets the standards and is sold as medium chain triglyceride oil.
The use of medium chain triglyceride oil having a melting point below 20 ℃ such that the oil is liquid at room temperature also provides advantages for the manufacture of homogenized tobacco material. For example, MCT oil does not need to be heated and melted compared to other lipids such as waxes because it naturally exists as a liquid at room temperature. Tobacco material, which is typically derived from homogenization of pulp, does not need to be heated to keep the oil in liquid form. The manufacturing process can be performed without external heating. This not only simplifies the manufacturing process, but also avoids the loss of volatile compounds from the tobacco-containing material during external heating. Furthermore, the use of MCT in the homogenized tobacco material also addresses the viscosity problems typically found in aerosol-generating articles when lipids are used in the manufacturing process. The viscous nature of lipids prevents efficient release of volatile compounds compared to MCT.
The inventors of the present invention have found from the test results that MCT works best in extracting volatile compounds from tobacco-containing materials when the MCT to tobacco material dry basis ratio is between 1. It has been found that in these samples, not only are off-flavors and off-tastes typically present in lipid-containing samples (e.g., waxes) no longer evident, it also provides the strongest tobacco aroma and flavor, as well as the highest nicotine delivery, to the consumer.
The diffusivity of volatile compounds (such as aerosol formers and nicotine) in the liquid phase is greater than the diffusivity in the solid phase. Thus, the liquid medium chain triglycerides will act to promote the transfer of volatile compounds within the particulate tobacco material to its surface. Thus, the transfer of these volatile compounds from the particulate tobacco material to the aerosol can be enhanced as compared to a homogenized tobacco material that does not contain liquid medium chain triglyceride oil within a particular desired ratio. Interestingly, the inventors found that samples can be immediately identified as less preferred choices when the dry basis ratio of MCT to tobacco material is outside the claimed range of 1. This is particularly evident when the samples contain MCT to tobacco material dry basis ratios of 1. It was therefore concluded that a certain minimum percentage threshold of MCT to tobacco material was required for optimal extraction and release of volatile compounds as an aerosol, as it allows the formation of a good mixture of open-cell and closed-cell foam.
The medium chain triglyceride oil is preferably uniformly distributed throughout the tobacco-containing material, meaning that there are no separately distinguishable regions of oil and plant material at room temperature. In contrast, oils and particles are completely homogenized or particulate.
The use of a homogenized tobacco material having medium chain triglyceride oil incorporated therein, as described herein, may allow for equal nicotine or aerosol production at lower heating temperatures as compared to the use of a homogenized tobacco material without the defined medium chain triglyceride oil. In fact, it has been surprisingly found that the use of a particulate tobacco-containing material having a ratio of medium chain triglycerides as defined herein at a lower heating temperature can provide a higher nicotine or aerosol yield than the nicotine or aerosol yield provided by the same material at a higher heating temperature. The possibility of using lower heating temperatures may provide a number of benefits when the compositions of the present invention are used in aerosol generating devices as they are intended, for example heated non-combustible devices. For example, a lower operating temperature may allow for longer periods of use of the aerosol generating device without recharging the battery. As a further example, lower operating temperatures may allow for the use of smaller batteries. As a further example, lower operating temperatures may reduce the release of undesirable aerosol components from the homogenized tobacco material.
Example 1
The aerosol-generating tobacco-containing composition according to the invention is prepared from tobacco material mixed with MCT oil. The resulting compositions formed aerosol generating materials, which in this example were provided in powder form, each having a different percentage/ratio of composition, and which had been tested using the methods described herein:
Figure BDA0003568135080000091
table 1: aerosol generating materials provided in powder form have different dry basis ratios of MCT to tobacco containing material.
MCT oils for powders B, C, D and E were obtained from Bayer AG (B)Subclause Sensory of alchem Company)
Figure BDA0003568135080000093
The Richmix 5025IP obtained (175755). For each tobacco sample, powdered/particulate tobacco was made into an aerosol-generating substrate using conventional techniques. In accordance with the present invention, there is provided an aerosol-generating article incorporating powders B, C, D and E, having medium chain triglyceride oil in a tobacco-containing material. Aerosol-generating articles incorporating powder a that did not include medium chain triglyceride oil were control samples for comparative purposes.
Examples of cellulose fibers may be, for example
Figure BDA0003568135080000094
2000 and the guar gum may be, for example, food grade gellan gum.
Each aerosol-generating article was subjected to the heating test defined above at 360 ℃ and 280 ℃. The nicotine levels in the aerosols delivered from each aerosol-generating article were measured and the results are shown in table 2 below.
Nicotine levels are measured using the ISO method for measuring tar, nicotine and carbon monoxide (TNCO) content in cigarettes and are determined using a smoking machine that smokes according to established methods. In the EU, this method is widely referred to as the ISO method and is specified by the european union committee. It is mentioned herein that other methods such as Canadian intense smoking method (Canadian intense method) can also be used for the measurement.
Figure BDA0003568135080000092
Table 2: nicotine delivery efficiency at two different heating temperatures.
As can be seen from table 2, an increased delivery of nicotine from the aerosol-generating tobacco-containing composition was observed in all aerosol-generating articles that had incorporated medium chain triglycerides in the tobacco-containing material relative to the control sample (powder a). However, only the samples in powders C and D showed the most significant improvement in nicotine delivery. This demonstrates that volatile compounds can be efficiently released when an optimal ratio of MCT to tobacco-containing material is selected. Of these ratios, the ratio of 1. Surprisingly, it was observed that a lower heating temperature (e.g. 280 ℃) promotes the release of higher amounts of nicotine in the aerosol compared to those samples where the aerosol generating substrate (tobacco containing composition) is heated at 360 ℃.
Example 2
The same experiment was repeated with the aerosol-generating tobacco-containing composition of the present invention, whereby the aerosol-generating tobacco-containing composition in this example was provided in the form of a foam or mousse. The foam properties and their manufacture are known in the art, for example as described in patent document WO 2018/122375 A1, except that MCT and its ratio to tobacco-containing material are used in the present invention.
All other parameters were similar to those described in example 1, except for the fact that the aerosol-generating tobacco-containing composition was provided in the form of a foam.
Figure BDA0003568135080000101
Table 3: the aerosol generating material provided in the form of a foam or mousse has different dry basis ratios of MCT to tobacco containing material.
Each aerosol-generating article was subjected to the heating test defined above at 360 ℃ and 280 ℃. The nicotine levels in the aerosols delivered from each aerosol-generating article were measured and the results are shown in table 3 below.
Figure BDA0003568135080000102
Figure BDA0003568135080000111
Table 4: nicotine delivery efficiency at two different heating temperatures.
As can be seen in Table 4, when the aerosol-generating tobacco-containing composition is provided in the form of a foam or mousse, a significant increase in the efficiency of nicotine delivery is observed compared to example 1. In other words, when higher release rates of volatile compounds, such as nicotine, are sought, aerosol-generating substrates in the form of a foam are a more preferred choice than aerosol-generating substrates in the form of a powder.
Similar to example 1, it has been found that a lower heating temperature, i.e. 280 ℃, is more effective in releasing volatile compounds than heating the aerosol generating material of the present invention at a higher temperature of 360 ℃. Furthermore, MCT of 1.
These results show that the use of an aerosol-generating tobacco-containing material having medium chain triglyceride oil incorporated therein provides increased nicotine or aerosol production as compared to a homogenized tobacco material having the same amount of tobacco but without the defined medium chain triglyceride oil. Moreover, this effect is notably observed when the dry basis ratio of MCT to tobacco-containing material is between 1.

Claims (21)

1. A tobacco-containing composition provided in the form of a foam or mousse that produces an aerosol, wherein the composition comprises a particulate tobacco material and a lipid, wherein the lipid is a medium chain triglyceride in a ratio of between 1.
2. The composition according to claim 1, wherein the particulate tobacco material has a particle size of less than 100 μm.
3. A composition according to claim 2, wherein the particulate tobacco material has a particle size of less than 90 μm.
4. A composition according to claim 2, wherein the particulate tobacco material has a particle size of less than 80 μm.
5. A composition according to claim 2, wherein the particulate tobacco material has a particle size of less than 70 μm.
6. A composition according to claim 2, wherein the particulate tobacco material has a particle size of less than 60 μm.
7. A composition according to claim 2, wherein the particulate tobacco material has a particle size of less than 50 μm.
8. The composition according to claim 2, wherein the particle size of the particulate tobacco material is between 40 μ ι η and 90 μ ι η.
9. The composition according to claim 1, wherein the ratio of medium chain triglycerides to tobacco-containing material is 1.
10. The composition according to claim 1, wherein the lipid is derived from palm kernel oil or coconut oil.
11. The composition of claim 1, wherein the lipid consists of caprylic acid (C8: 0), capric acid (C10: 0) and/or lauric acid (C12: 0).
12. Composition according to claim 1, wherein more than 50wt. -% of the lipid is MCT octanoic acid (C8: 0), based on the total weight of the lipid.
13. Composition according to claim 12, wherein more than 60wt. -% of the lipid is MCT octanoic acid (C8: 0), based on the total weight of the lipid.
14. Composition according to claim 12, wherein more than 66wt. -% of the lipid is MCT octanoic acid (C8: 0), based on the total weight of the lipid.
15. The composition according to claim 1, wherein the composition further comprises maltodextrin gum arabic, silica, and/or sunflower lecithin.
16. The composition according to claim 1, wherein the composition comprises any of a propellant, an aerosol former, a foam stabilizer and/or a foam former.
17. A composition according to claim 1, wherein the composition comprises an aerosol former in a proportion of 10-80wt. -% based on the weight of the aerosol generating material.
18. A composition according to claim 17, wherein the composition comprises an aerosol former in a proportion of 30-70wt. -% based on the weight of the aerosol generating material.
19. A method of making an aerosol-generating tobacco-containing foam or mousse comprising the steps of:
a. mixing the aerosol former, foam former and optionally solvent under heating;
b. aerating the mixture with gas or air at room temperature for at least 5 minutes;
c. adding a tobacco-containing component and/or an inhalant to the mixture;
d. optionally aerating the mixture with gas or air;
e. adding medium chain triglycerides to the mixture, wherein the ratio of medium chain triglycerides to the tobacco-containing material is between 1;
f. aerating the mixture with gas or air at room temperature for at least 5 minutes;
g. adding a foam stabilizer.
20. The method according to claim 19, wherein in each step the mixture is aerated with heated gas or air between 35 ℃ and 50 ℃ for at least 10 minutes.
21. An aerosol-generating article comprising the aerosol-generating tobacco-containing composition of any one of claims 1-18.
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