CN114452332A - A method for preparing herba Houttuyniae micropowder - Google Patents
A method for preparing herba Houttuyniae micropowder Download PDFInfo
- Publication number
- CN114452332A CN114452332A CN202210280415.3A CN202210280415A CN114452332A CN 114452332 A CN114452332 A CN 114452332A CN 202210280415 A CN202210280415 A CN 202210280415A CN 114452332 A CN114452332 A CN 114452332A
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- houttuynia cordata
- pipeline
- coarse powder
- powder
- coarse
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- A—HUMAN NECESSITIES
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C19/00—Other disintegrating devices or methods
- B02C19/0012—Devices for disintegrating materials by collision of these materials against a breaking surface or breaking body and/or by friction between the material particles (also for grain)
- B02C19/005—Devices for disintegrating materials by collision of these materials against a breaking surface or breaking body and/or by friction between the material particles (also for grain) the materials to be pulverised being disintegrated by collision of, or friction between, the material particles
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B02—CRUSHING, PULVERISING, OR DISINTEGRATING; PREPARATORY TREATMENT OF GRAIN FOR MILLING
- B02C—CRUSHING, PULVERISING, OR DISINTEGRATING IN GENERAL; MILLING GRAIN
- B02C19/00—Other disintegrating devices or methods
- B02C19/06—Jet mills
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- Disintegrating Or Milling (AREA)
Abstract
The invention discloses a preparation method of houttuynia cordata ultra-micro powder, which comprises the following operation steps: the method comprises the following steps: placing the coarse houttuynia cordata powder in a supersonic air flow collider to form supersonic air flow with the coarse houttuynia cordata powder in a first pipeline and a second pipeline; step two: in the first pipeline, positive electricity discharge needles are used for ionizing to generate negative ions, and then the first ion accelerating device is used for accelerating the houttuynia cordata coarse powder particles with negative electricity; step three: in the second pipeline, positive ions are generated through ionization of negative discharge needles, and the houttuynia cordata coarse powder particles with positive charges are accelerated through a second ion accelerating device; step four: and carrying out ultramicro collision at the intersection of the first pipeline and the second pipeline, wherein the collided houttuynia cordata powder is circularly collided through the first pipeline and the second pipeline. The technical scheme is used for solving the problems of low production efficiency, high energy consumption and low wall breaking rate of the existing method for preparing the houttuynia cordata powder by low-temperature airflow supersonic speed clash.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicine treatment, and particularly relates to a preparation method of houttuynia cordata superfine powder.
Background
The aerial part of houttuynia cordata contains volatile oil and decanoyl acetaldehyde (decaurealyde), lauraldehyde (lauricaldehyde), alpha-pinene (alpha-pinene) and linalool (linaol) which are effective components for resisting bacteria, and the former two have specific odor. It also contains methyL n-nonyl ketone (methyL-n-nonylketone), camphene (camphene), myrcene (myrcene), limonene (limonene), bornyl acetate (bornylacetate) and caryophyllene (caryophylelene). The term houttuynine sodium bisulfite refers to the addition product of hydrogen sulfite of decanoic acid acetaldehyde. It also contains afzelin, hyperoside, rutin, chlorogenic acid, beta-sitosterol, stearic acid, oleic acid and linoleic acid. The leaves contain quercetin (quercitririn), and the flowers and ears contain isoquercitrin (iso-qUercitrin).
Yu xing Cao is pungent in flavor and cold in nature and enters lung meridian. It has effects of clearing away heat and toxic materials, relieving swelling, treating sore, inducing diuresis, removing dampness, clearing away heat, relieving dysentery, invigorating stomach, and resolving food stagnation, and can be used for treating lung abscess, pyocutaneous disease, hemorrhoid hematochezia, and heat accumulation of spleen and stomach due to excess heat, heat toxin, dampness, and disease heat. Modern pharmacological experiments show that the product has antibacterial, antiviral, immunity improving, and diuretic effects.
The houttuynia cordata is widely used due to its excellent efficacy, but at present, the houttuynia cordata is mainly eaten in a cooking or water soaking mode, and high temperature can damage the active ingredients in the houttuynia cordata which are not high in temperature resistance, so that the effect is reduced.
The medicinal utilization rate of the houttuynia cordata can be improved by breaking the wall of the houttuynia cordata and crushing the houttuynia cordata, and the houttuynia cordata can be used in lower water temperature, but the existing wall breaking crushing mode, such as low-temperature airflow supersonic collision, needs to be circulated for many times to obtain powder meeting the requirements, has the problems of low production efficiency, high energy consumption and serious consumption of compressed gas, and has lower wall breaking rate, and the medicinal effect is influenced.
Disclosure of Invention
Aiming at the technical problems, the invention provides a preparation method of houttuynia cordata superfine powder, which aims to solve the problems of low production efficiency, high energy consumption and low wall breaking rate of the conventional method for preparing the houttuynia cordata powder by low-temperature airflow supersonic collision.
The invention provides a preparation method of houttuynia cordata ultra-micro powder, which comprises the following operation steps:
the method comprises the following steps: placing the coarse houttuynia cordata powder in a supersonic air flow collider to form supersonic air flow with the coarse houttuynia cordata powder in a first pipeline and a second pipeline;
step two: in the first pipeline, positive electricity discharge needles are used for ionizing to generate negative ions, the negative ions are attached to the houttuynia cordata coarse powder to form houttuynia cordata coarse powder particles with negative electricity, and the houttuynia cordata coarse powder particles with negative electricity are accelerated by a first ion accelerating device;
step three: in a second pipeline, positive ions are generated through ionization of a negative discharge needle, the positive ions are attached to the houttuynia cordata coarse powder to form houttuynia cordata coarse powder particles with positive electricity, and the houttuynia cordata coarse powder particles with positive electricity are accelerated through a second ion accelerating device;
step four: at the intersection of the first and second pipelines, negatively charged herba Houttuyniae coarse powder particles are ejected from supersonic nozzle, positively charged herba Houttuyniae coarse powder particles are ejected from supersonic nozzle for ultramicro collision, and collided herba Houttuyniae powder is circularly collided via the first and second pipelines.
Further, before the step one, the following operations are further included:
pulverizing herba Houttuyniae, and sieving with 100 mesh sieve to obtain herba Houttuyniae coarse powder.
Further, before coarse crushing, the houttuynia cordata is dried at a temperature of 80 + -5 deg.C.
Further, a first compressed gas supply device is connected to the first pipeline; and a second compressed gas supply device is connected to the second pipeline.
Furthermore, the device also comprises a high-voltage power supply device, and the positive electric discharge needles and the negative electric discharge needles are respectively and electrically connected to the high-voltage power supply device.
Further, the ion source comprises an electromagnetic generator, the first ion accelerating device comprises a plurality of first electromagnetic accelerating coils, the second ion accelerating device comprises a plurality of second electromagnetic accelerating coils, the first electromagnetic accelerating coils surround the periphery of the first pipeline, and the second electromagnetic accelerating coils surround the periphery of the second pipeline.
Furthermore, after the materials are subjected to ultramicro collision, the cell wall breaking rate reaches 95%, and the average particle size is less than or equal to 30 microns.
In order to improve the crushing efficiency, refine the powder and realize the wall breaking effect, the preparation method of the houttuynia cordata superfine powder is additionally provided with a positive electric discharge needle, a first ion accelerating device, a negative electric discharge needle and a second ion accelerating device on the basis of the prior airflow supersonic speed clash, positive ions and negative ions are respectively generated by the positive discharge needles and the negative discharge needles to charge the houttuynia cordata particles, further realizing further acceleration to the houttuynia cordata particles through the first ion accelerating device and the second ion accelerating device, and then make the houttuynia cordata particles have bigger kinetic energy when carrying out the super little collision, the houttuynia cordata particles that simultaneously charges with positive electricity and negatively also have the effect of inter attraction, effectively improved the collision probability, and the superfine powder of houttuynia cordata that finally obtains has lower particle diameter and higher broken wall rate, reduces the cycle number, improves production efficiency, reduces the power consumption.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
FIG. 1 is a schematic view of the flow structure of the process for preparing houttuynia cordata ultra-fine powder.
Detailed Description
The invention discloses a preparation method of houttuynia cordata ultra-micro powder, which can effectively improve the production efficiency and the quality of the obtained houttuynia cordata ultra-micro powder.
The technical solutions of the present invention will be described clearly and completely with reference to the accompanying drawings, and obviously, the description is only a part of the embodiments of the present invention, not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1, the invention discloses a preparation method of houttuynia cordata ultra-micro powder, which comprises the following operation steps:
the method comprises the following steps: placing herba Houttuyniae coarse powder in supersonic air flow collider to form supersonic air flow with herba Houttuyniae coarse powder in first and second pipelines 6 and 7;
step two: in the first pipeline 6, the positive electricity discharge needles 2 are ionized to generate negative ions, the negative ions are attached to the houttuynia cordata coarse powder to form houttuynia cordata coarse powder particles with negative electricity, and the houttuynia cordata coarse powder particles with negative electricity are accelerated by the first ion acceleration device 8;
step three: in the second pipeline 7, positive ions are generated by ionization of the negative electricity discharge needle 4, the positive ions are attached to the houttuynia cordata coarse powder to form positively charged houttuynia cordata coarse powder particles, and the positively charged houttuynia cordata coarse powder particles are accelerated by the second ion accelerating device 1;
step four: at the intersection of the first pipeline 6 and the second pipeline 7, the negatively charged herba Houttuyniae coarse powder particles are ejected from the supersonic nozzle, the positively charged herba Houttuyniae coarse powder particles are ejected from the supersonic nozzle for ultramicro collision, and the collided herba Houttuyniae powder is circularly collided via the first pipeline 6 and the second pipeline 7.
In order to improve the crushing efficiency, refine the powder and realize the wall breaking effect, the preparation method of the houttuynia cordata ultra-micro powder is additionally provided with the positive electric discharge needle 2, the first ion accelerating device 8, the negative electric discharge needle 4 and the second ion accelerating device 1 on the basis of the prior airflow supersonic collision, positive ions and negative ions are respectively generated by the positive electric discharge needle 2 and the negative electric discharge needle 4 to charge houttuynia cordata particles, the houttuynia cordata particles are further accelerated by the first ion accelerating device 8 and the second ion accelerating device 1, the houttuynia cordata particles have larger kinetic energy when in the process of the ultra-micro collision, the positively charged and negatively charged houttuynia cordata particles also have the function of mutual attraction, the collision probability is effectively improved, the finally obtained houttuynia cordata ultra-micro powder has lower particle size and higher wall breaking rate, and the cycle number is reduced, the production efficiency is improved, and the energy consumption is reduced.
Before the first step, the following operations are further included:
pulverizing herba Houttuyniae, and sieving with 100 mesh sieve to obtain herba Houttuyniae coarse powder.
Before coarse crushing, the houttuynia cordata is dried at the temperature of 80 +/-5 ℃.
A first compressed gas supply device is connected to the first pipeline 6; a second compressed gas supply is connected to the second pipe 7.
The device also comprises a high-voltage power supply device 3, and the positive electric discharge needle 2 and the negative electric discharge needle 4 are respectively and electrically connected to the high-voltage power supply device 3.
The ion source further comprises an electromagnetic generator 5, the first ion accelerating device 8 comprises a plurality of first electromagnetic accelerating coils, the second ion accelerating device 1 comprises a plurality of second electromagnetic accelerating coils, the first electromagnetic accelerating coils surround the periphery of the first pipeline 6, and the second electromagnetic accelerating coils surround the periphery of the second pipeline 7.
After the materials are subjected to ultramicro collision, the cell wall breaking rate reaches 95%, and the average particle size is less than or equal to 30 mu m.
The invention is further illustrated by the following specific examples:
example 1
The method comprises the following steps: sieving herba Houttuyniae with 100 mesh sieve to obtain herba Houttuyniae coarse powder, placing herba Houttuyniae coarse powder in supersonic air flow collider, and forming supersonic air flow with herba Houttuyniae coarse powder in first and second pipelines;
step two: in the first pipeline, positive electricity discharge needles are used for ionizing to generate negative ions, the negative ions are attached to the houttuynia cordata coarse powder to form houttuynia cordata coarse powder particles with negative electricity, and the houttuynia cordata coarse powder particles with negative electricity are accelerated by a first ion accelerating device;
step three: in a second pipeline, positive ions are generated through ionization of a negative discharge needle, the positive ions are attached to the houttuynia cordata coarse powder to form houttuynia cordata coarse powder particles with positive electricity, and the houttuynia cordata coarse powder particles with positive electricity are accelerated through a second ion accelerating device;
step four: at the intersection of the first pipeline and the second pipeline, the negatively charged herba Houttuyniae coarse powder particles are ejected from the supersonic nozzle, the positively charged herba Houttuyniae coarse powder particles are ejected from the supersonic nozzle for ultramicro collision, and the collided herba Houttuyniae powder is circularly collided for 1h via the first pipeline and the second pipeline.
Example 2
The method comprises the following steps: sieving herba Houttuyniae with 100 mesh sieve to obtain herba Houttuyniae coarse powder, placing herba Houttuyniae coarse powder in supersonic air flow collider, and forming supersonic air flow with herba Houttuyniae coarse powder in first and second pipelines;
step two: in the first pipeline, positive electricity discharge needles are used for ionizing to generate negative ions, the negative ions are attached to the houttuynia cordata coarse powder to form houttuynia cordata coarse powder particles with negative electricity, and the houttuynia cordata coarse powder particles with negative electricity are accelerated by a first ion accelerating device;
step three: in a second pipeline, positive ions are generated through ionization of a negative discharge needle, the positive ions are attached to the houttuynia cordata coarse powder to form houttuynia cordata coarse powder particles with positive electricity, and the houttuynia cordata coarse powder particles with positive electricity are accelerated through a second ion accelerating device;
step four: at the intersection of the first and second pipelines, negatively charged herba Houttuyniae coarse powder particles are ejected from supersonic nozzle, positively charged herba Houttuyniae coarse powder particles are ejected from supersonic nozzle for ultramicro collision, and collided herba Houttuyniae powder is circularly collided for 1.5h via the first and second pipelines.
Comparative example 1
The method comprises the following steps: sieving herba Houttuyniae with 100 mesh sieve to obtain herba Houttuyniae coarse powder, placing herba Houttuyniae coarse powder in supersonic air flow collider, and forming supersonic air flow with herba Houttuyniae coarse powder in first and second pipelines;
step two: at the intersection of the first pipeline and the second pipeline, the houttuynia cordata coarse powder particles are sprayed out by a supersonic nozzle for ultramicro collision, and the collided houttuynia cordata powder is collided for 1 hour in a circulating way through the first pipeline and the second pipeline.
Comparative example 2
The method comprises the following steps: sieving herba Houttuyniae with 100 mesh sieve to obtain herba Houttuyniae coarse powder, placing herba Houttuyniae coarse powder in supersonic air flow collider, and forming supersonic air flow with herba Houttuyniae coarse powder in first and second pipelines;
step two: at the intersection of the first pipeline and the second pipeline, the houttuynia cordata coarse powder particles are sprayed out by a supersonic nozzle for ultramicro collision, and the collided houttuynia cordata powder circularly collides for 1.5 hours through the first pipeline and the second pipeline.
Results testing
The average particle size and wall-breaking rate of the powder of the houttuynia cordata superfine powder prepared in the above examples and comparative examples were measured, and the results are shown in the following table:
the above test data show that compared with low-temperature airflow supersonic collision, the preparation method of the houttuynia cordata ultrafine powder provided by the invention can effectively reduce the crushing degree of the powder and effectively improve the wall breaking rate.
The foregoing is a more detailed description of the invention in connection with specific preferred embodiments and it is not intended that the invention be limited to these specific details. For those skilled in the art to which the invention pertains, several simple deductions or substitutions can be made without departing from the spirit of the invention, and all shall be considered as belonging to the protection scope of the invention.
Claims (7)
1. The preparation method of the houttuynia cordata superfine powder is characterized by comprising the following operation steps:
the method comprises the following steps: placing the coarse houttuynia cordata powder in a supersonic air flow collider to form supersonic air flow with the coarse houttuynia cordata powder in a first pipeline and a second pipeline;
step two: in the first pipeline, positive electricity discharge needles are used for ionizing to generate negative ions, the negative ions are attached to the houttuynia cordata coarse powder to form houttuynia cordata coarse powder particles with negative electricity, and the houttuynia cordata coarse powder particles with negative electricity are accelerated by a first ion accelerating device;
step three: in a second pipeline, positive ions are generated through ionization of a negative discharge needle, the positive ions are attached to the houttuynia cordata coarse powder to form houttuynia cordata coarse powder particles with positive electricity, and the houttuynia cordata coarse powder particles with positive electricity are accelerated through a second ion accelerating device;
step four: at the intersection of the first and second pipelines, negatively charged herba Houttuyniae coarse powder particles are ejected from supersonic nozzle, positively charged herba Houttuyniae coarse powder particles are ejected from supersonic nozzle for ultramicro collision, and collided herba Houttuyniae powder is circularly collided via the first and second pipelines.
2. The method of claim 1, further comprising the steps of, before the first step:
pulverizing herba Houttuyniae, and sieving with 100 mesh sieve to obtain herba Houttuyniae coarse powder.
3. The method of claim 2, wherein the houttuynia cordata Thunb is dried at a temperature of 80 ± 5 ℃ before being coarsely pulverized.
4. The method of claim 1, wherein a first compressed gas supply is connected to the first pipe; and a second compressed gas supply device is connected to the second pipeline.
5. The method of claim 1, further comprising a high voltage power supply, wherein the positive discharge needles and the negative discharge needles are electrically connected to the high voltage power supply.
6. The method of claim 1, further comprising an electromagnetic generator, wherein the first ion accelerator comprises a plurality of first electromagnetic accelerating coils, the second ion accelerator comprises a plurality of second electromagnetic accelerating coils, the first electromagnetic accelerating coils surround the outer periphery of the first tube, and the second electromagnetic accelerating coils surround the outer periphery of the second tube.
7. The method for preparing houttuynia cordata ultra-fine powder according to claim 1, wherein the material has a cell wall breaking rate of 95% and an average particle size of 30 μm or less after ultra-fine collision.
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115998827A (en) * | 2022-12-02 | 2023-04-25 | 西藏昌都光宇利民药业有限责任公司 | Preparation process of ten-ingredient gymnadenia conopsea powder |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106269139A (en) * | 2016-09-29 | 2017-01-04 | 西南科技大学 | A kind of method improving airflow milling Particle Acceleration performance |
-
2022
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Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106269139A (en) * | 2016-09-29 | 2017-01-04 | 西南科技大学 | A kind of method improving airflow milling Particle Acceleration performance |
Non-Patent Citations (1)
| Title |
|---|
| 李健等: ""鱼腥草超微粉的显微特性"", 《福建农林大学学报（自然科学版）》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115998827A (en) * | 2022-12-02 | 2023-04-25 | 西藏昌都光宇利民药业有限责任公司 | Preparation process of ten-ingredient gymnadenia conopsea powder |
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