CN114432735B - Coriolus versicolor glycopeptide preparation device - Google Patents
Coriolus versicolor glycopeptide preparation device Download PDFInfo
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- CN114432735B CN114432735B CN202210079044.2A CN202210079044A CN114432735B CN 114432735 B CN114432735 B CN 114432735B CN 202210079044 A CN202210079044 A CN 202210079044A CN 114432735 B CN114432735 B CN 114432735B
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- 241000222355 Trametes versicolor Species 0.000 title claims abstract description 47
- DQJCDTNMLBYVAY-ZXXIYAEKSA-N (2S,5R,10R,13R)-16-{[(2R,3S,4R,5R)-3-{[(2S,3R,4R,5S,6R)-3-acetamido-4,5-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-5-(ethylamino)-6-hydroxy-2-(hydroxymethyl)oxan-4-yl]oxy}-5-(4-aminobutyl)-10-carbamoyl-2,13-dimethyl-4,7,12,15-tetraoxo-3,6,11,14-tetraazaheptadecan-1-oic acid Chemical compound NCCCC[C@H](C(=O)N[C@@H](C)C(O)=O)NC(=O)CC[C@H](C(N)=O)NC(=O)[C@@H](C)NC(=O)C(C)O[C@@H]1[C@@H](NCC)C(O)O[C@H](CO)[C@H]1O[C@H]1[C@H](NC(C)=O)[C@@H](O)[C@H](O)[C@@H](CO)O1 DQJCDTNMLBYVAY-ZXXIYAEKSA-N 0.000 title claims abstract description 26
- 102000002068 Glycopeptides Human genes 0.000 title claims abstract description 26
- 108010015899 Glycopeptides Proteins 0.000 title claims abstract description 26
- 238000002360 preparation method Methods 0.000 title claims abstract description 20
- 238000000605 extraction Methods 0.000 claims abstract description 106
- 238000003825 pressing Methods 0.000 claims abstract description 80
- 238000007789 sealing Methods 0.000 claims description 14
- 238000001914 filtration Methods 0.000 claims description 9
- 230000002093 peripheral effect Effects 0.000 claims description 7
- 230000001105 regulatory effect Effects 0.000 claims description 5
- 239000011148 porous material Substances 0.000 claims 3
- 238000000926 separation method Methods 0.000 claims 2
- 230000007423 decrease Effects 0.000 claims 1
- 239000007788 liquid Substances 0.000 description 38
- 238000009792 diffusion process Methods 0.000 description 20
- 238000004140 cleaning Methods 0.000 description 19
- 230000000694 effects Effects 0.000 description 8
- 229920000642 polymer Polymers 0.000 description 6
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 5
- 238000010586 diagram Methods 0.000 description 5
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- 230000004151 fermentation Effects 0.000 description 5
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- 239000006228 supernatant Substances 0.000 description 4
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- 238000009835 boiling Methods 0.000 description 3
- 230000002708 enhancing effect Effects 0.000 description 3
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- 230000000091 immunopotentiator Effects 0.000 description 3
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- 241000233866 Fungi Species 0.000 description 2
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- 238000005516 engineering process Methods 0.000 description 2
- 238000001125 extrusion Methods 0.000 description 2
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- 101100298222 Caenorhabditis elegans pot-1 gene Proteins 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 241000222356 Coriolus Species 0.000 description 1
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- 238000006424 Flood reaction Methods 0.000 description 1
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- 241000222341 Polyporaceae Species 0.000 description 1
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/02—Solvent extraction of solids
- B01D11/028—Flow sheets
- B01D11/0284—Multistage extraction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Extraction Or Liquid Replacement (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Abstract
The invention discloses a Coriolus versicolor glycopeptide preparation device, which relates to the technical field of Coriolus versicolor glycopeptide preparation and comprises an extraction tank and an end cover arranged at the top opening of the extraction tank; a mycelium extraction basket is arranged in the extraction tank, and a filter pressing assembly is movably arranged in the mycelium extraction basket; the end cover is connected with a filter pressing driving piece, the filter pressing driving piece penetrates through the filter pressing assembly and extends to the bottom of the mycelium extraction basket, and the filter pressing driving piece is used for driving the filter pressing assembly to lift and adjust along the mycelium extraction basket.
Description
Technical Field
The invention relates to the technical field of coriolus versicolor glycopeptide preparation, in particular to a coriolus versicolor glycopeptide preparation device.
Background
The corious versicolor glycopeptide is a polymer glycopeptide polymer extracted from mycelium of corious versicolor which is a plant of Polyporaceae, has the effects of replenishing vital essence, strengthening spleen and nourishing heart, has a certain protection effect on cell immunity and hemogram, and is used for treating deficiency of both qi and yin and heart and spleen caused by radiotherapy and chemotherapy of patients with esophageal cancer, gastric cancer and primary lung cancer. The immunopotentiator can improve animal immunity, relieve animal immunosuppression, and enhance animal resistance to bacterial and viral infectious diseases. Therefore, the research and application of the immunopotentiator in animal production are increasingly attracting great attention from scholars at home and abroad. Coriolus versicolor glycopeptide is also called an immune adjuvant, and is a substance for enhancing nonspecific and specific immunity of animal bodies through different action modes, such as enhancing macrophage activity, enhancing immunogenicity and stability of antigen substances, promoting synthesis and secretion of antibodies and the like. With advances in science and technology and improvements in veterinary technology, the selection of an ideal immunopotentiator with defined characteristics, high efficiency, stability, and low toxic and side effects will be the main approach and means for the future resistance to diseases.
The preparation method of the coriolus versicolor glycopeptide comprises the steps of introducing steam to enable the temperature in a fermentation tank to be 100-102 ℃ after fermentation of coriolus versicolor fermentation liquid is finished, boiling and extracting for 1-2 h, wherein the application publication number is CN113150063A, the application publication date is 2021.07.23, and the name is a Chinese patent application of the novel preparation method of coriolus versicolor glycopeptide; cooling the fermentation liquor to room temperature, discharging the fermentation liquor, centrifuging, and collecting supernatant and precipitate; adding water into the precipitate, boiling for extraction, centrifuging, collecting supernatant and mycelium residues, boiling for extraction, centrifuging, collecting supernatant, discarding mycelium residues, mixing the obtained supernatant and concentrating to a relative density of 1.05-1.15; adding 95% ethanol into the concentrated solution, and precipitating with ethanol at 4deg.C overnight; centrifuging the liquid after alcohol precipitation, collecting precipitate, and oven drying.
As in the above application, when the polymer glycopeptide polymer is extracted from the mycelium of coriolus versicolor, the mycelium of coriolus versicolor needs to be extracted for a plurality of times by using the extracting solution, and when the mycelium is extracted for a plurality of times, the mycelium of coriolus versicolor after the extracting treatment needs to be pressed after each time, so that the extracting solution is completely discharged, the secondary extracting effect is ensured, then the pressed mycelium residues are spread out, and the residues are re-placed into the extracting tank to be extracted by adding the extracting solution, so that the mycelium is repeatedly extracted for a plurality of times in the prior art, the operation procedure is complicated, and the working efficiency is affected.
Disclosure of Invention
The invention aims to provide a coriolus versicolor glycopeptide preparation device which aims to solve the defects in the prior art.
In order to achieve the above object, the present invention provides the following technical solutions: a Coriolus versicolor glycopeptide preparation device comprises an extraction tank and an end cover arranged at the top opening of the extraction tank; a mycelium extraction basket is arranged in the extraction tank, and a filter pressing assembly is movably arranged in the mycelium extraction basket; the end cover is connected with a filter pressing driving piece, and the filter pressing driving piece penetrates through the filter pressing assembly and extends to the bottom of the mycelium extraction basket, and the filter pressing driving piece is used for driving the filter pressing assembly to lift and adjust along the mycelium extraction basket.
As a further description of the above technical solution: a plurality of groups of filter holes are formed in the periphery of the mycelium extraction basket, and the filter holes in each group are arranged in annular equal angles along the peripheral surface of the mycelium extraction basket.
As a further description of the above technical solution: and sealing assemblies are rotatably arranged at positions, corresponding to the filtering holes, on the inner sides of the mycelium extraction baskets.
As a further description of the above technical solution: when the filter pressing assembly descends and passes through the sealing assembly, the filter pressing assembly drives the sealing assembly to seal the filtering holes, and when the filter pressing assembly ascends and passes through the sealing assembly, the filter pressing assembly drives the sealing assembly to open the filtering holes.
As a further description of the above technical solution: the filter pressing driving piece comprises a central shaft, the central shaft is rotationally connected to the end cover, and the bottom end of the central shaft extends to the bottom center position of the mycelium extraction basket.
As a further description of the above technical solution: the upper part of the peripheral surface of the central shaft is provided with an adjusting screw thread, and the lower part of the peripheral surface of the central shaft is connected with a folding diffusion frame.
As a further description of the above technical solution: the filter-pressing subassembly includes the filter-pressing dish, the filter-pressing dish lift type inlays to be established the inboard of hypha extraction basket, the central point of filter-pressing dish puts and is provided with the connecting cylinder, the connection screw has been seted up at the top of connecting cylinder, the folding through-hole has been seted up to the below that is located the connection screw on the connecting cylinder.
As a further description of the above technical solution: the sealing assembly comprises annular adjusting grooves formed in the inner side of the mycelium extraction basket and at positions corresponding to the filtering holes, and annular baffle plates are rotatably arranged in the annular adjusting grooves.
As a further description of the above technical solution: the annular baffle is provided with a plurality of through holes which are arranged corresponding to the filtering holes, and the inner side of the annular baffle is positioned between the through holes and is obliquely provided with a guide adjusting groove.
As a further description of the above technical solution: the periphery of the filter pressing assembly is provided with a plurality of adjusting convex parts matched with the guiding adjusting grooves.
According to the coriolus versicolor glycopeptide preparation device, the filter pressing driving piece drives the filter pressing assembly positioned in the mycelium extraction basket to perform descending adjustment, coriolus versicolor mycelium positioned in the mycelium extraction basket is pressed, so that the absorption extracting solution in coriolus versicolor mycelium is completely discharged, and then the filter pressing driving piece drives the filter pressing assembly positioned in the mycelium extraction basket to perform ascending adjustment, so that the pressed coriolus versicolor mycelium re-absorbs the extracting solution for secondary extraction, automatic pressing and discharging of the extracting solution for coriolus versicolor mycelium is realized, then the re-absorbing extracting solution is extracted, repeated multi-time extraction is realized, working steps are reduced, and working efficiency is remarkably improved.
Drawings
In order to more clearly illustrate the embodiments of the present application or the technical solutions in the prior art, the drawings that are needed in the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments described in the present invention, and other drawings may be obtained according to these drawings for a person having ordinary skill in the art.
FIG. 1 is a schematic diagram of the overall structure of a Coriolus versicolor glycopeptide preparation device according to an embodiment of the present invention;
FIG. 2 is a schematic diagram of an assembly structure of a liquid supply mechanism and an extraction tank according to an embodiment of the present invention;
FIG. 3 is a schematic view showing an internal structure of a mycelium pellet according to an embodiment of the present invention;
FIG. 4 is a schematic view of the internal structure of a liquid supply box according to an embodiment of the present invention;
FIG. 5 is a schematic diagram of a mycelium pellet according to an embodiment of the present invention;
FIG. 6 is a schematic structural view of an annular baffle according to an embodiment of the present invention;
FIG. 7 is a schematic diagram of a filter assembly according to an embodiment of the present invention;
FIG. 8 is a schematic view of a foldable diffusion frame according to an embodiment of the present invention;
fig. 9 is a schematic diagram of an assembly structure of a cleaning socket according to an embodiment of the present invention.
Reference numerals illustrate:
1. an extraction tank; 11. an end cap; 12. a driving motor; 13. a central shaft; 131. folding the diffusion frame; 1311. a hinge base; 1312. a diffusion swing rod; 132. adjusting the screw thread; 14. an extract discharge port; 2. a mycelium extracting basket; 21. a connection hole; 22. a filter hole; 23. an axial limit frame; 24. an annular adjusting groove; 25. an annular baffle; 251. a through hole; 252. a guide adjusting groove; 3. a liquid supply mechanism; 31. a liquid supply box; 311. a one-way bearing seat; 312. a liquid outlet hole; 313. a rotating seat; 314. a liquid supply blade; 32. an arc-shaped liquid supply pipe; 321. a liquid inlet connecting pipe; 322. a liquid supply joint; 4. a filter pressing assembly; 41. a filter pressing disc; 42. an adjusting protrusion; 43. a connecting cylinder; 431. folding the through hole; 432. a connecting screw hole; 5. cleaning the sleeve seat; 51. cleaning the notch; 52. a strip-shaped flange; 53. a bar-shaped groove.
Detailed Description
In order to make the technical scheme of the present invention better understood by those skilled in the art, the present invention will be further described in detail with reference to the accompanying drawings.
Referring to fig. 1-9, the embodiment of the present invention provides a technical solution: a Coriolus versicolor glycopeptide preparation device comprises an extraction tank 1 and an end cover 11 arranged at the top of the extraction tank 1 and provided with an opening; a mycelium extraction basket 2 is arranged in the extraction tank 1, and a filter pressing component 4 is movably arranged in the mycelium extraction basket 2; the end cover 11 is connected with a filter pressing driving piece, the filter pressing driving piece penetrates through the filter pressing assembly 4 and extends to the bottom of the mycelium extraction basket 2, the filter pressing driving piece is used for driving the filter pressing assembly 4 to lift and adjust along the mycelium extraction basket 2, a plurality of groups of filter holes 22 are formed in the periphery of the mycelium extraction basket 2, and all groups of filter holes 22 are arranged in annular equal angles along the periphery of the mycelium extraction basket 2. The embodiment provides a coriolus versicolor glycopeptide preparation device, which is a device for extracting high molecular glycopeptide polymer from coriolus versicolor mycelium, specifically, the device comprises an extraction tank 1, the extraction tank 1 is of a tank body structure with an open top, an extracting solution discharge port 14 is arranged at the bottom center position of the extraction tank 1, an end cover 11 is arranged on the top opening of the extraction tank 1, a mycelium extraction basket 2 is arranged at the inner center position of the extraction tank 1, when the high molecular glycopeptide polymer is extracted from coriolus versicolor mycelium, the treated coriolus versicolor mycelium is loaded on the mycelium extraction basket 2, extracting solution is injected into the extraction tank 1, then the end cover 11 is fixed on the top opening of the extraction tank 1, when the coriolus versicolor mycelium is extracted, a filter pressing assembly 4 positioned in the mycelium extraction basket 2 is driven by a filter pressing driving piece to be regulated downwards, the coriolus versicolor mycelium positioned in the mycelium extraction basket 2 is enabled to be completely discharged, then the coriolus versicolor mycelium is driven by the filter pressing driving piece 4 positioned in the mycelium extraction basket 2 to be electrically regulated, and the filter pressing assembly 4 is driven to be electrically regulated to be a new weight, and the coriolus versicolor mycelium can be extracted again, and the weight can be extracted again and repeatedly. The embodiment provides a coriolus versicolor glycopeptide preparation device, which realizes automatic pressing and discharging of extracting solution for coriolus versicolor mycelium, and then reabsorption of the extracting solution for extraction, realizes repeated extraction, reduces working steps, and obviously improves working efficiency.
In another embodiment of the present invention, the filter press driving member comprises a central shaft 13, wherein the central shaft 13 is rotatably connected to the end cover 11, and the bottom end of the central shaft 13 extends to the bottom center position of the mycelium extraction basket 2. An adjusting screw 132 is provided on the upper part of the peripheral surface of the central shaft 13, and a folding diffusion frame 131 is connected to the lower part of the peripheral surface of the central shaft 13. The filter pressing assembly 4 comprises a filter pressing disc 41, the filter pressing disc 41 is embedded on the inner side of the mycelium extraction basket 2 in a lifting mode, a connecting cylinder 43 is arranged at the center position of the filter pressing disc 41, a connecting screw hole 432 is formed in the top of the connecting cylinder 43, and a folding through hole 431 is formed in the connecting cylinder 43 and located below the connecting screw hole 432. Further, the filter pressing driving piece comprises a central shaft 13, the central shaft 13 is rotatably connected to the inner side center position of the end cover 11, a driving motor 12 is arranged outside the end cover 11, the driving motor 12 is in transmission connection with the central shaft 13 through a coupler, the driving motor 12 is a bidirectional rotation motor, an adjusting screw thread 132 is arranged on the periphery of the central shaft 13, a folding diffusion frame 131 is connected to the lower portion of the periphery of the central shaft 13, the folding diffusion frame 131 comprises a hinge seat 1311, the hinge seat 1311 is fixed to the outer side of the central shaft 13, a diffusion swing rod 1312 is rotatably connected to the hinge seat 1311 through a rotating shaft, a torsion spring is further sleeved on the rotating shaft, the elasticity of the torsion spring is identical to that of the driving diffusion swing rod 1312, the connecting cylinder 43 is in spiral sleeve connection with the upper end of the central shaft 13 through a connecting screw hole 432 at the top of the connecting cylinder 43, further, the mycelium extraction basket 2 is of a cylindrical structure with an open top, the inner wall of the mycelium extraction basket 2 is vertically and equiangularly provided with a plurality of axial limiting frames 23, a filter pressing disc 41 is embedded in the inner side of the mycelium extraction basket 2 in a lifting manner, the circumferential side of the filter pressing disc 41 is provided with limiting grooves matched with the axial limiting frames 23, the filter pressing disc 41 can only lift and move in the mycelium extraction basket 2 and can not axially rotate through the matching of the axial limiting frames 23 and the limiting grooves, when the filter pressing driving piece drives the filter pressing assembly 4 to lift and adjust along the mycelium extraction basket 2, the central shaft 13 is driven to positively rotate through the driving motor 12, the central shaft 13 is matched with the adjusting screw threads 132 on the central shaft to drive the filter pressing disc 41 to downwards move in the mycelium extraction basket 2 through the connecting cylinder 43, and similarly, the central shaft 13 is driven to reversely rotate through the driving motor 12, the central shaft 13 is matched with the adjusting screw threads 132 on the central shaft to drive the filter pressing disc 41 to lift in the mycelium extraction basket 2 through the connecting cylinder 43, the automatic extrusion of coriolus versicolor mycelium is realized, then the extraction is carried out in the automatic extrusion discharge extract, and the reabsorption extract is carried out, realize reciprocating multiple times extraction, and when spindle 13 rotates, the folding diffusion frame 131 of its bottom section is driven to rotate by spindle 13 in step, thereby realize carrying out auxiliary diffusion to coriolus versicolor mycelium after pressing, and carry out repeated extraction with coriolus versicolor mycelium secondary absorption extract after pressing, further improve the extraction effect, and when spindle 13 cooperates the adjusting screw 132 on it to drive filter disc 41 to move down in mycelium extraction basket 2 through connecting cylinder 43, folding through hole 431 bottom opening butt folding diffusion frame 131 on connecting cylinder 43, make the diffusion pendulum rod 1312 on the folding diffusion frame 131 rotate folding along the length direction of spindle 13, thereby make folding diffusion frame 131 built-in folding through hole 431 after folding, thereby can not cause the interference to filter disc 41 moves down.
In still another embodiment of the present invention, a sealing assembly is rotatably provided at a position corresponding to each group of the filter holes 22 on the inner side of the mycelium pellet 2. When the filter pressing assembly 4 descends to pass through the sealing assembly, the filter pressing assembly 4 drives the sealing assembly to seal the filter holes 22, and when the filter pressing assembly 4 ascends to pass through the sealing assembly, the filter pressing assembly 4 drives the sealing assembly to open the filter holes 22. The seal assembly comprises annular adjusting grooves 24 formed in the inner side of the mycelium extraction basket 2 and corresponding to the groups of filter holes 22, annular baffle plates 25 are rotatably arranged in the annular adjusting grooves 24, wherein the inner walls of the annular baffle plates 25 protrude to the inner side of the mycelium extraction basket 2, the annular baffle plates are of a non-annular flange structure, the filter pressing plates 41 are of disc-shaped structures, the diameters of the filter pressing plates are matched with the inner diameters of the annular baffle plates 25, a plurality of through holes 251 which are correspondingly arranged with the filter holes 22 are formed in the annular baffle plates 25, namely, when the through holes 251 in the annular baffle plates 25 are aligned with the filter holes 22 one by one, the filter holes 22 are kept in a conducting state, when the through holes 251 in the annular baffle plates 25 rotate and are mutually staggered with the filter holes 22, the filter holes 22 are kept in a blocking state, and the inner sides of the annular baffle plates 25 are positioned between the through holes 251 and are obliquely provided with guide adjusting grooves 252. The horizontal distance between the top end and the tail end of the guide adjusting groove 252 is larger than the length of the filtering holes 22, and a plurality of adjusting convex parts 42 matched with the guide adjusting groove 252 are arranged on the periphery of the filter pressing assembly 4. Specifically, when the central shaft 13 is matched with the adjusting screw threads 132 on the central shaft 13 to drive the press filter disc 41 to move downwards in the mycelium extraction basket 2 through the connecting cylinder 43, the adjusting convex parts 42 on the periphery of the press filter disc 41 are embedded into the guiding adjusting grooves 252 in a sliding way, when the press filter disc 41 continues to move downwards, the annular baffle 25 is driven to rotate and adjust in the annular adjusting grooves 24 under the action of the inclined guiding adjusting grooves 252, so that when the through holes 251 on the annular baffle 25 are rotated and staggered with the filter holes 22, the filter holes 22 on the mycelium extraction basket 2 keep a blocking state, namely when the press filter disc 41 presses coriolus versicolor mycelium, the synchronous driving sealing assembly is used for blocking a plurality of groups of filter holes 22 on the mycelium extraction basket 2 one by one, when the central shaft 13 matched with the adjusting screw threads 132 on the central shaft is driven to rise in the mycelium extraction basket 2 through the connecting cylinder 43, the adjusting convex part 42 on the periphery of the filter pressing disc 41 is matched with the inclined guide adjusting groove 252 to drive the annular baffle 25 to rotate and reset in the annular adjusting groove 24, so that a group of filter holes 22 at the bottom of the mycelium extraction basket 2 are opened, the filter holes 22 are sequentially opened from the bottom to the top of the mycelium extraction basket 2 by moving upwards, so that the extracting solution in the extraction tank 1 quickly floods from the filter holes 22 at the bottom of the mycelium extraction basket 2, the effect of assisting in impact diffusion of the coriolus versicolor mycelium pressed at the bottom of the mycelium extraction basket 2 is realized, the coriolus versicolor mycelium can be uniformly diffused into the inner space of the mycelium extraction basket 2, the effect of extracting the coriolus versicolor mycelium by secondary absorption is further improved, and the compressed coriolus versicolor mycelium is not required to be matched with external equipment or manually diffused and loosened by workers.
In still another embodiment of the present invention, preferably, the bottom of the mycelium extraction basket 2 is disposed at the inner side of the extraction tank 1, the liquid supply mechanism 3 includes a liquid supply box 31 and an arc liquid supply pipe 32, the center position of the top of the liquid supply box 31 is rotatably provided with a unidirectional bearing seat 311, the top of the unidirectional bearing seat 311 is provided with an opposite port, the bottom end of the central shaft 13 is inserted on the opposite port, the top of the liquid supply box 31 is disposed at the outer side of the unidirectional bearing seat 311 and is uniformly provided with a liquid outlet 312, the inner side of the liquid supply box 31 is rotatably provided with a rotary seat 313, the rotary seat 313 is rotatably connected with the unidirectional bearing seat 311 in a unidirectional manner, i.e. when the unidirectional bearing seat 311 rotates in a forward direction, the unidirectional bearing seat 311 synchronously drives the rotary seat 313 to rotate, the outer side of the rotary seat 313 is connected with a liquid supply blade 314, the bottom of the mycelium extraction basket 2 is provided with a connecting hole 21, the connecting hole 21 is communicated with the liquid outlet 312, the bottom of the liquid supply box 31 is also connected with the arc liquid supply pipe 32, the arc liquid supply pipe 32 extends from the bottom of the extraction tank 1 to the top of the extraction tank 1 to the outer side of the extraction tank 1, and the arc liquid supply pipe is connected with the arc liquid supply pipe 322, and the outer side of the arc liquid supply pipe is connected with the arc liquid supply pipe 322 is further connected with the inner cavity 32.
When the extracting solution in the extracting pot 1 is used for repeated extraction for a plurality of times, the central shaft 13 is driven to rotate forwards through the driving motor 12, the adjusting screw threads 132 on the central shaft 13 are matched with the central shaft 13 to drive the dynamic pressure filter disc 41 to move downwards in the mycelium extracting basket 2 through the connecting cylinder 43, the central shaft 13 is driven to rotate reversely through the driving motor 12, the adjusting screw threads 132 on the central shaft 13 are matched with the central shaft to drive the dynamic pressure filter disc 41 to rise in the mycelium extracting basket 2 through the connecting cylinder 43, automatic pressing and extracting solution discharging of coriolus versicolor mycelia is realized, then the extracting solution is re-absorbed for extraction for a plurality of times, and the reciprocating extraction is realized, wherein when the driving motor 12 drives the central shaft 13 to rotate forwards, the unidirectional bearing seat 311 is synchronously driven to rotate, the unidirectional bearing seat 311 does not drive the rotating seat 313, when the driving motor 12 drives the central shaft 13 to rotate reversely, the adjusting screw threads 132 on the central shaft 13 are matched with the central shaft 13 to drive the dynamic pressure filter disc 41 to rise in the mycelium extracting basket 2 through the connecting cylinder 43, the unidirectional bearing seat 311 synchronously drives the rotating seat 313 to rotate reversely, the coriolus versicolor mycelia to be matched with the liquid blades 314 on the outer side of the rotating seat 313 to automatically press the coriolus versicolor mycelia, the coriolus versicolor mycelia is supplied with the extracting solution to be extracted from the top of the mycelium extracting basket 2 through the connecting pot 21, and the concentration of the extracting solution can be further improved from the top of the extracting solution is more evenly than the extracting basket 2, and the extracting solution can be extracted from the top of the mycelium extracting solution can be filled into the extracting pot 2 through the hole of the extracting pot 2, and the extracting solution can be more evenly filled into the extracting solution is filled into the extracting solution from the bottom hole of the bottom of the extracting pot 2.
When extracting liquid is added for repeated extraction for multiple times, a control valve arranged on the liquid inlet connecting pipe 321 is closed, extracting liquid is injected into the arc-shaped liquid supply pipe 32 through the liquid supply connector 322, when the driving motor 12 drives the central shaft 13 to reversely rotate, the central shaft 13 is matched with the adjusting screw threads 132 on the central shaft to drive the dynamic pressure filter disc 41 to ascend in the mycelium extraction basket 2 through the connecting cylinder 43, at the moment, the central shaft 13 synchronously drives the unidirectional bearing seat 311 to reversely rotate, the unidirectional bearing seat 311 synchronously drives the rotating seat 313 to rotate, and the liquid supply blades 314 outside the rotating seat 313 rotate, so that the injected extracting liquid is filled into the mycelium extraction basket 2 from the bottom of the mycelium extraction basket 2 through the liquid outlet 312 matched with the connecting hole 21 at the top of the liquid supply box 31, so that the pressed coriolus mycelium can uniformly spread into the inner space of the mycelium extraction basket 2, the pressed coriolus versicolor mycelium is directly extracted for the second time through the added extracting liquid, and the extracting effect is remarkably improved.
In still another embodiment provided by the invention, preferably, the central shaft 13 is also sleeved with the cleaning sleeve seat 5 in a lifting sliding manner, the cleaning sleeve seat 5 is in transmission connection with the filter pressing assembly 4, and when the filter pressing assembly 4 moves downwards along the mycelium pellet extraction basket 2, the cleaning sleeve seat 5 automatically cleans the coriolus versicolor mycelium wound and attached on the folding and diffusing frame 131. Specifically, the cleaning sleeve seat 5 is slidingly sleeved on the central shaft 13, the central shaft 13 is provided with a strip-shaped groove 53, the inner side of the cleaning sleeve seat 5 is integrally formed with a strip-shaped flange 52, the strip-shaped flange 52 is embedded in the strip-shaped groove 53, the inner side of the bottom opening of the cleaning sleeve seat 5 is provided with a cleaning notch 51 corresponding to the folding diffusion frame 131, the cleaning sleeve seat 5 is rotationally connected with the inner wall of the folding through hole 431 in the connecting cylinder 43 through a rotating bearing, namely, when the central shaft 13 rotates to drive the connecting cylinder 43 to move up and down, the cleaning sleeve seat 5 and the central shaft 13 keep synchronously rotating, so that the cleaning notch 51 on the cleaning sleeve seat 5 always keeps corresponding to the folding diffusion frame 131, and when the connecting cylinder 43 is driven to move up and down to synchronously drive the cleaning sleeve seat 5 to move up and down, so that the cleaning notch 51 on the cleaning sleeve seat 5 is in butt joint with the diffusion swing rod 1312 on the folding diffusion frame 131, and the automatic cleaning of the attachment of the corious fungus mycelia in a winding manner is realized through the downward movement of the cleaning sleeve seat 5, and the corious fungus glycopeptide preparation device is more convenient to use.
While certain exemplary embodiments of the present invention have been described above by way of illustration only, it will be apparent to those of ordinary skill in the art that modifications may be made to the described embodiments in various different ways without departing from the spirit and scope of the invention. Accordingly, the drawings and description are to be regarded as illustrative in nature and not as restrictive of the scope of the invention, which is defined by the appended claims.
Claims (4)
1. The corious versicolor glycopeptide preparation device is characterized by comprising an extraction tank (1) and an end cover (11) arranged at the top opening of the extraction tank (1); a mycelium extraction basket (2) is arranged in the extraction tank (1), and a filter pressing assembly (4) is movably arranged in the mycelium extraction basket (2); the end cover (11) is connected with a filter pressing driving piece, the filter pressing driving piece penetrates through the filter pressing assembly (4) and extends to the bottom of the mycelium extraction basket (2), and the filter pressing driving piece is used for driving the filter pressing assembly (4) to lift and adjust along the mycelium extraction basket (2);
a plurality of groups of filter holes (22) are formed in the periphery of the mycelium extraction basket (2), each group of filter holes (22) are formed in a ring shape at equal angles along the periphery of the mycelium extraction basket (2), a sealing assembly is rotatably arranged at the position, corresponding to each group of filter holes (22), of the inner side of the mycelium extraction basket (2), the sealing assembly comprises a ring-shaped regulating groove (24) formed at the position, corresponding to each group of filter holes (22), of the inner side of the mycelium extraction basket (2), and a ring-shaped baffle (25) is rotatably arranged in the ring-shaped regulating groove (24);
when filter-pressing subassembly (4) decline to pass seal the subassembly, filter-pressing subassembly (4) drive seal the subassembly with seal the filtration pore (22) and carry out the shutoff, works as filter-pressing subassembly (4) rise to pass seal the subassembly, filter-pressing subassembly (4) drive seal the subassembly with the filtration pore (22) is opened, set up a plurality of with through-hole (251) that filter pore (22) correspond the setting on annular separation blade (25), and the inboard of annular separation blade (25) is located slope between through-hole (251) has been seted up guide adjustment groove (252), the week side of filter-pressing subassembly (4) is provided with adjustment convex part (42) that a plurality of cooperation guide adjustment grooves (252) used.
2. The corious versicolor glycopeptide preparation device according to claim 1, wherein the press filtration driving member comprises a central shaft (13), the central shaft (13) is rotatably connected to the end cover (11), and the bottom end of the central shaft (13) extends to the bottom center position of the mycelium extraction basket (2).
3. The corious versicolor glycopeptide preparation device according to claim 2, wherein an adjusting screw thread (132) is provided on the upper part of the peripheral surface of the central shaft (13), and a folding and spreading frame (131) is connected to the lower part of the peripheral surface of the central shaft (13).
4. The coriolus versicolor glycopeptide preparation device according to claim 1, wherein the filter pressing assembly (4) comprises a filter pressing disc (41), the filter pressing disc (41) is embedded in the inner side of the mycelium extraction basket (2) in a lifting mode, a connecting cylinder (43) is arranged at the central position of the filter pressing disc (41), a connecting screw hole (432) is formed in the top of the connecting cylinder (43), and a folding through hole (431) is formed in the connecting cylinder (43) and located below the connecting screw hole (432).
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| CN115177978B (en) * | 2022-09-09 | 2022-11-22 | 长沙市惠瑞生物科技有限公司 | Plant extraction element that can circulate and draw in succession |
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| CN209837229U (en) * | 2019-04-09 | 2019-12-24 | 南华大学 | Environment-friendly unpowered rain and sewage separation structure |
| CN212972718U (en) * | 2020-08-11 | 2021-04-16 | 浙江绍兴苏泊尔生活电器有限公司 | Tea making container |
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| JP4388715B2 (en) * | 2001-05-14 | 2009-12-24 | 光彦 棚橋 | Extraction method and extractor for plant-derived extract |
| CN209794637U (en) * | 2018-09-05 | 2019-12-17 | 山东泓瑞医药科技股份公司 | Pharmacy filter-press jar |
| CN210874215U (en) * | 2019-10-28 | 2020-06-30 | 郑州大学第二附属医院 | Traditional chinese medicine liquid medicine extraction element |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN209837229U (en) * | 2019-04-09 | 2019-12-24 | 南华大学 | Environment-friendly unpowered rain and sewage separation structure |
| CN212972718U (en) * | 2020-08-11 | 2021-04-16 | 浙江绍兴苏泊尔生活电器有限公司 | Tea making container |
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Effective date of registration: 20240724 Address after: Room 3001, 3rd Floor, Incubation Building, Hainan Ecological Software Park, Laocheng High tech Industry Demonstration Zone, Chengmai County, Sansha City, Hainan Province, 571900 Patentee after: Hainan Longfengpu Biotechnology Co.,Ltd. Country or region after: China Address before: 510663 no.492 Daguan Middle Road, Dongpu, Tianhe District, Guangzhou, Guangdong Province Patentee before: LINGNAN INSTITUTE OF TECHNOLOGY Country or region before: China |