CN114432202A - Toothpaste containing psicose and preparation method thereof - Google Patents
Toothpaste containing psicose and preparation method thereof Download PDFInfo
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- CN114432202A CN114432202A CN202210156173.7A CN202210156173A CN114432202A CN 114432202 A CN114432202 A CN 114432202A CN 202210156173 A CN202210156173 A CN 202210156173A CN 114432202 A CN114432202 A CN 114432202A
- Authority
- CN
- China
- Prior art keywords
- toothpaste
- allulose
- psicose
- humectant
- abrasive
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Links
- 229940034610 toothpaste Drugs 0.000 title claims abstract description 49
- 239000000606 toothpaste Substances 0.000 title claims abstract description 49
- LKDRXBCSQODPBY-JDJSBBGDSA-N D-allulose Chemical compound OCC1(O)OC[C@@H](O)[C@@H](O)[C@H]1O LKDRXBCSQODPBY-JDJSBBGDSA-N 0.000 title claims abstract description 40
- 238000002360 preparation method Methods 0.000 title claims abstract description 14
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims abstract description 16
- 239000003906 humectant Substances 0.000 claims abstract description 13
- 239000004088 foaming agent Substances 0.000 claims abstract description 12
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 claims abstract description 8
- 235000001855 Portulaca oleracea Nutrition 0.000 claims abstract description 8
- 241000219304 Portulacaceae Species 0.000 claims abstract description 8
- 229930003268 Vitamin C Natural products 0.000 claims abstract description 8
- 239000008367 deionised water Substances 0.000 claims abstract description 8
- 229910021641 deionized water Inorganic materials 0.000 claims abstract description 8
- 235000019154 vitamin C Nutrition 0.000 claims abstract description 8
- 239000011718 vitamin C Substances 0.000 claims abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 238000000034 method Methods 0.000 claims abstract description 7
- 230000008569 process Effects 0.000 claims abstract description 6
- 239000000853 adhesive Substances 0.000 claims abstract description 5
- 230000001070 adhesive effect Effects 0.000 claims abstract description 5
- DNIAPMSPPWPWGF-UHFFFAOYSA-N Propylene glycol Chemical compound CC(O)CO DNIAPMSPPWPWGF-UHFFFAOYSA-N 0.000 claims description 9
- 239000002994 raw material Substances 0.000 claims description 9
- 230000001954 sterilising effect Effects 0.000 claims description 9
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 8
- 239000011230 binding agent Substances 0.000 claims description 8
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 6
- 238000004659 sterilization and disinfection Methods 0.000 claims description 6
- FBPFZTCFMRRESA-FSIIMWSLSA-N D-Glucitol Natural products OC[C@H](O)[C@H](O)[C@@H](O)[C@H](O)CO FBPFZTCFMRRESA-FSIIMWSLSA-N 0.000 claims description 3
- FBPFZTCFMRRESA-JGWLITMVSA-N D-glucitol Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO FBPFZTCFMRRESA-JGWLITMVSA-N 0.000 claims description 3
- 229920002907 Guar gum Polymers 0.000 claims description 3
- 239000004354 Hydroxyethyl cellulose Substances 0.000 claims description 3
- 229920000663 Hydroxyethyl cellulose Polymers 0.000 claims description 3
- DBMJMQXJHONAFJ-UHFFFAOYSA-M Sodium laurylsulphate Chemical group [Na+].CCCCCCCCCCCCOS([O-])(=O)=O DBMJMQXJHONAFJ-UHFFFAOYSA-M 0.000 claims description 3
- DPXJVFZANSGRMM-UHFFFAOYSA-N acetic acid;2,3,4,5,6-pentahydroxyhexanal;sodium Chemical compound [Na].CC(O)=O.OCC(O)C(O)C(O)C(O)C=O DPXJVFZANSGRMM-UHFFFAOYSA-N 0.000 claims description 3
- WNROFYMDJYEPJX-UHFFFAOYSA-K aluminium hydroxide Chemical compound [OH-].[OH-].[OH-].[Al+3] WNROFYMDJYEPJX-UHFFFAOYSA-K 0.000 claims description 3
- 229910000019 calcium carbonate Inorganic materials 0.000 claims description 3
- JUNWLZAGQLJVLR-UHFFFAOYSA-J calcium diphosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])(=O)OP([O-])([O-])=O JUNWLZAGQLJVLR-UHFFFAOYSA-J 0.000 claims description 3
- 229940043256 calcium pyrophosphate Drugs 0.000 claims description 3
- 239000001768 carboxy methyl cellulose Substances 0.000 claims description 3
- 239000000679 carrageenan Substances 0.000 claims description 3
- 235000010418 carrageenan Nutrition 0.000 claims description 3
- 229920001525 carrageenan Polymers 0.000 claims description 3
- 229940113118 carrageenan Drugs 0.000 claims description 3
- 235000019821 dicalcium diphosphate Nutrition 0.000 claims description 3
- 235000011187 glycerol Nutrition 0.000 claims description 3
- 239000000665 guar gum Substances 0.000 claims description 3
- 235000010417 guar gum Nutrition 0.000 claims description 3
- 229960002154 guar gum Drugs 0.000 claims description 3
- 235000019447 hydroxyethyl cellulose Nutrition 0.000 claims description 3
- 229940071826 hydroxyethyl cellulose Drugs 0.000 claims description 3
- 239000000843 powder Substances 0.000 claims description 3
- RMAQACBXLXPBSY-UHFFFAOYSA-N silicic acid Chemical compound O[Si](O)(O)O RMAQACBXLXPBSY-UHFFFAOYSA-N 0.000 claims description 3
- 235000012239 silicon dioxide Nutrition 0.000 claims description 3
- 235000019812 sodium carboxymethyl cellulose Nutrition 0.000 claims description 3
- 229920001027 sodium carboxymethylcellulose Polymers 0.000 claims description 3
- 235000019333 sodium laurylsulphate Nutrition 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 3
- 239000000600 sorbitol Substances 0.000 claims description 3
- 238000009849 vacuum degassing Methods 0.000 claims description 3
- 239000000230 xanthan gum Substances 0.000 claims description 3
- 235000010493 xanthan gum Nutrition 0.000 claims description 3
- 229920001285 xanthan gum Polymers 0.000 claims description 3
- 229940082509 xanthan gum Drugs 0.000 claims description 3
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 claims description 3
- 235000010216 calcium carbonate Nutrition 0.000 claims 1
- FUFJGUQYACFECW-UHFFFAOYSA-L calcium hydrogenphosphate Chemical compound [Ca+2].OP([O-])([O-])=O FUFJGUQYACFECW-UHFFFAOYSA-L 0.000 claims 1
- 235000019700 dicalcium phosphate Nutrition 0.000 claims 1
- 238000000265 homogenisation Methods 0.000 claims 1
- BJHIKXHVCXFQLS-PUFIMZNGSA-N D-psicose Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)C(=O)CO BJHIKXHVCXFQLS-PUFIMZNGSA-N 0.000 description 8
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 3
- 239000008103 glucose Substances 0.000 description 3
- 235000000346 sugar Nutrition 0.000 description 3
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 239000011575 calcium Substances 0.000 description 2
- 229910052791 calcium Inorganic materials 0.000 description 2
- 238000004140 cleaning Methods 0.000 description 2
- 230000036541 health Effects 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 235000013615 non-nutritive sweetener Nutrition 0.000 description 2
- 201000001320 Atherosclerosis Diseases 0.000 description 1
- 206010006326 Breath odour Diseases 0.000 description 1
- 102100021943 C-C motif chemokine 2 Human genes 0.000 description 1
- 101710155857 C-C motif chemokine 2 Proteins 0.000 description 1
- RFSUNEUAIZKAJO-VRPWFDPXSA-N D-Fructose Natural products OC[C@H]1OC(O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-VRPWFDPXSA-N 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 208000004930 Fatty Liver Diseases 0.000 description 1
- RFSUNEUAIZKAJO-ARQDHWQXSA-N Fructose Chemical compound OC[C@H]1O[C@](O)(CO)[C@@H](O)[C@@H]1O RFSUNEUAIZKAJO-ARQDHWQXSA-N 0.000 description 1
- 206010019708 Hepatic steatosis Diseases 0.000 description 1
- 206010022489 Insulin Resistance Diseases 0.000 description 1
- 102000014962 Monocyte Chemoattractant Proteins Human genes 0.000 description 1
- 108010064136 Monocyte Chemoattractant Proteins Proteins 0.000 description 1
- 229930006000 Sucrose Natural products 0.000 description 1
- CZMRCDWAGMRECN-UGDNZRGBSA-N Sucrose Chemical compound O[C@H]1[C@H](O)[C@@H](CO)O[C@@]1(CO)O[C@@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 CZMRCDWAGMRECN-UGDNZRGBSA-N 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000006907 apoptotic process Effects 0.000 description 1
- 235000015173 baked goods and baking mixes Nutrition 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- XZYRJVLKSRQAGD-UHFFFAOYSA-N bis(2-Ethylhexyl)phthalic acid Chemical compound CCCCC(CC)CC1=CC=C(C(O)=O)C(C(O)=O)=C1CC(CC)CCCC XZYRJVLKSRQAGD-UHFFFAOYSA-N 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 230000007850 degeneration Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 208000010706 fatty liver disease Diseases 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 235000003599 food sweetener Nutrition 0.000 description 1
- 230000002641 glycemic effect Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000006698 induction Effects 0.000 description 1
- 230000000968 intestinal effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000000324 neuroprotective effect Effects 0.000 description 1
- DIVDFFZHCJEHGG-UHFFFAOYSA-N oxidopamine Chemical compound NCCC1=CC(O)=C(O)C=C1O DIVDFFZHCJEHGG-UHFFFAOYSA-N 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- -1 oxygen radicals Chemical class 0.000 description 1
- 230000000291 postprandial effect Effects 0.000 description 1
- 239000003642 reactive oxygen metabolite Substances 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 235000019204 saccharin Nutrition 0.000 description 1
- CVHZOJJKTDOEJC-UHFFFAOYSA-N saccharin Chemical compound C1=CC=C2C(=O)NS(=O)(=O)C2=C1 CVHZOJJKTDOEJC-UHFFFAOYSA-N 0.000 description 1
- 229940081974 saccharin Drugs 0.000 description 1
- 239000000901 saccharin and its Na,K and Ca salt Substances 0.000 description 1
- 230000002000 scavenging effect Effects 0.000 description 1
- 231100000240 steatosis hepatitis Toxicity 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 239000005720 sucrose Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000003765 sweetening agent Substances 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
- 210000001550 testis Anatomy 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/24—Phosphorous; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/26—Aluminium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
- A61K8/463—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur containing sulfuric acid derivatives, e.g. sodium lauryl sulfate
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/60—Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/676—Ascorbic acid, i.e. vitamin C
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/731—Cellulose; Quaternized cellulose derivatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/737—Galactomannans, e.g. guar; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/20—Chemical, physico-chemical or functional or structural properties of the composition as a whole
- A61K2800/28—Rubbing or scrubbing compositions; Peeling or abrasive compositions; Containing exfoliants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Inorganic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Emergency Medicine (AREA)
- Cosmetics (AREA)
Abstract
The invention relates to the technical field of toothpaste preparation, in particular to a toothpaste containing psicose and a preparation method thereof, which reduce the residue of the toothpaste after use, increase the mouthfeel in the use process and improve the protection period of teeth; comprises an abrasive, psicose, a humectant, a foaming agent, an adhesive, vitamin C, purslane and deionized water; the toothpaste comprises the following components in parts by weight: 35-50% of an abrasive, 2-3% of allulose, 14-32% of a humectant, 2-2.4% of a foaming agent, 1-1.3% of an adhesive, 0.8-1.4% of vitamin C, 2-3% of purslane and 16-24% of deionized water.
Description
Technical Field
The invention relates to the technical field of toothpaste preparation, in particular to a toothpaste containing psicose and a preparation method thereof.
Background
As is well known, toothpaste is one of the tooth cleaning products, generally in the form of gel, and is usually applied to a toothbrush, and the mechanical friction of the toothbrush is used to clean the surfaces of teeth, clean the teeth and their surroundings, and clean the mouth, so that the teeth are beautiful, the gum health is protected, and bad breath is prevented, and tooth cleaning is the most important. Toothpaste has become a necessity in human daily life.
Psicose (D-psicose) is a six-carbon sugar with a very low content in nature, and is an epimer of the C-3 site of D-fructose. D-psicose is very difficult to digest and absorb and provides little energy for life activities, and thus is a very useful low-calorie sweetener. In the field of medical health, D-psicose can inhibit fatty liver enzymes and intestinal α -glycosidase, thereby reducing accumulation of fat in vivo and inhibiting increase in blood glucose concentration. Iida and Hayashi found that the addition of D-psicose to the diet reduced the postprandial glycemic response and increased insulin sensitivity and glucose tolerance. In addition, D-psicose is more effective in scavenging reactive oxygen radicals than other rare sugars. In mouse experiments, it was found that D-psicose can prevent bis- (2-ethylhexyl) -phthalic acid-induced damage to the testes by inhibiting the production of reactive oxygen species. In addition, the D-psicose has a neuroprotective effect on apoptosis induced by 6-hydroxydopamine, and can inhibit the expression of monocyte chemotactic protein MCP-1 under the induction of high-concentration glucose. Therefore, the D-psicose is indicated to have the potential function of treating related diseases such as nervous tissue degeneration, atherosclerosis and the like.
The biggest advantage of psicose over other low-calorie sweeteners is its extremely close character and function to sucrose, being safe enough to be "sugar" enough to achieve excellent sugar-substitution in applications where other sweeteners are difficult to be adequate, such as baked goods. Its main advantages are the following: low calorie, good taste, high safety, improved product quality and high stability. Therefore, allulose is now being used in other fields such as food, medical, and the like.
Saccharin is usually added in the preparation of the existing toothpaste to improve the mouth feel, and is easy to remain in the gaps between teeth and has poor mouth feel in the using process.
Disclosure of Invention
In order to solve the technical problems, the invention provides the allulose-containing toothpaste which reduces residues of the toothpaste after use, increases the mouthfeel in the use process and improves the protection period of teeth and the preparation method thereof.
The toothpaste containing psicose comprises an abrasive, psicose, a humectant, a foaming agent, a binder, vitamin C, purslane and deionized water;
the toothpaste comprises the following components in parts by weight: 35-50% of an abrasive, 2-3% of allulose, 14-32% of a humectant, 2-2.4% of a foaming agent, 1-1.3% of an adhesive, 0.8-1.4% of vitamin C, 2-3% of purslane and 16-24% of deionized water.
The toothpaste containing the psicose provided by the invention further comprises 0.8% -1% of essence.
The toothpaste containing the psicose comprises the abrasive which is one or more of calcium carbonate, calcium hydrophosphate, calcium pyrophosphate, hydrated silicic acid and aluminum hydroxide, and the weight percentage is 35-50%.
The toothpaste containing the psicose comprises the humectant which is one or more of glycerol, sorbitol and propylene glycol, and the weight percentage of the humectant is 14-32%.
According to the toothpaste containing psicose and the preparation method thereof, the foaming agent is sodium dodecyl sulfate, and the weight percentage is 2% -2.4%.
The toothpaste containing the psicose comprises the binder which is one or more of sodium carboxymethylcellulose, xanthan gum, hydroxyethyl cellulose, guar gum and carrageenan, and the weight percentage of the binder is 1-1.3%.
The preparation method of the toothpaste containing the psicose comprises the following specific steps:
quantitatively taking raw materials according to the components of the toothpaste in the defined proportion in the claims 1-7;
secondly, grinding the solid raw materials in the components to prepare powder;
thirdly, all the raw materials obtained in the first step and the second step are added into a container to be mixed and stirred evenly;
fourthly, sterilizing the mixture after being evenly stirred, wherein the sterilization temperature is 100-120 ℃, and the sterilization time is 25-30 s;
fifthly, grinding and vacuum degassing the obtained mixture.
According to the preparation method of the toothpaste containing the psicose, the prepared toothpaste is homogenized.
Compared with the prior art, the invention has the beneficial effects that: the toothpaste reduces the residues after use, increases the mouthfeel in the use process and improves the protection period of teeth.
Detailed Description
The following examples are given to further illustrate the embodiments of the present invention. The following examples are intended to illustrate the invention but are not intended to limit the scope of the invention.
The toothpaste containing psicose comprises an abrasive, psicose, a humectant, a foaming agent, a binder, vitamin C, purslane and deionized water;
the toothpaste comprises the following components in parts by weight: 35-50% of an abrasive, 2-3% of allulose, 14-32% of a humectant, 2-2.4% of a foaming agent, 1-1.3% of an adhesive, 0.8-1.4% of vitamin C, 2-3% of purslane and 16-24% of deionized water; the toothpaste reduces the residues after use, increases the mouthfeel in the use process and improves the protection period of teeth.
The toothpaste containing the psicose provided by the invention further comprises 0.8% -1% of essence.
The toothpaste containing the psicose comprises the abrasive which is one or more of calcium carbonate, calcium hydrophosphate, calcium pyrophosphate, hydrated silicic acid and aluminum hydroxide, and the weight percentage is 35-50%.
The toothpaste containing the psicose comprises the humectant which is one or more of glycerol, sorbitol and propylene glycol, and the weight percentage of the humectant is 14-32%.
The foaming agent of the toothpaste containing the allulose is sodium dodecyl sulfate, and the weight percentage of the foaming agent is 2% -2.4%.
The toothpaste containing the psicose comprises the binder which is one or more of sodium carboxymethylcellulose, xanthan gum, hydroxyethyl cellulose, guar gum and carrageenan, and the weight percentage of the binder is 1-1.3%.
The preparation method of the toothpaste containing the psicose comprises the following specific steps:
quantitatively taking raw materials according to the components of the toothpaste in the defined proportion in the claims 1-7;
secondly, grinding the solid raw materials in the components to prepare powder;
thirdly, all the raw materials obtained in the first step and the second step are added into a container to be mixed and stirred evenly;
fourthly, sterilizing the mixture after being evenly stirred, wherein the sterilization temperature is 100-120 ℃, and the sterilization time is 25-30 s;
fifthly, grinding and vacuum degassing the obtained mixture.
According to the preparation method of the toothpaste containing the psicose, the prepared toothpaste is homogenized.
The above description is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, several modifications and variations can be made without departing from the technical principle of the present invention, and these modifications and variations should also be regarded as the protection scope of the present invention.
Claims (8)
1. The toothpaste containing the psicose is characterized by comprising an abrasive, the psicose, a humectant, a foaming agent, a binding agent, vitamin C, purslane and deionized water;
the toothpaste comprises the following components in parts by weight: 35-50% of an abrasive, 2-3% of allulose, 14-32% of a humectant, 2-2.4% of a foaming agent, 1-1.3% of an adhesive, 0.8-1.4% of vitamin C, 2-3% of purslane and 16-24% of deionized water.
2. An allulose-containing toothpaste as claimed in claim 1, wherein said toothpaste component further comprises from 0.8% to 1% of a flavoring.
3. An allulose-containing toothpaste as claimed in claim 1, wherein the abrasive is comprised of one or more of calcium carbonate, calcium hydrogen phosphate, calcium pyrophosphate, hydrated silicic acid and aluminum hydroxide in an amount of 35% to 50% by weight.
4. An allulose-containing toothpaste as claimed in claim 1, wherein said humectant is comprised of one or more of glycerin, sorbitol and propylene glycol at a weight percentage of 14% to 32%.
5. An allulose-containing toothpaste according to claim 1, wherein the foaming agent is sodium lauryl sulfate and is present in a 2% to 2.4% by weight percentage.
6. The allulose-containing toothpaste according to claim 1, wherein the binder is one or more of sodium carboxymethylcellulose, xanthan gum, hydroxyethyl cellulose, guar gum, and carrageenan, and is present in an amount of 1% to 1.3% by weight.
7. The method of preparing a allulose-containing toothpaste according to claim 1, comprising the specific steps of:
quantitatively taking raw materials according to the components of the toothpaste in the defined proportion in the claims 1-7;
secondly, grinding the solid raw materials in the components to prepare powder;
thirdly, all the raw materials obtained in the first step and the second step are added into a container to be mixed and stirred evenly;
fourthly, sterilizing the mixture after being evenly stirred, wherein the sterilization temperature is 100-120 ℃, and the sterilization time is 25-30 s;
fifthly, grinding and vacuum degassing the obtained mixture.
8. A process for the preparation of a toothpaste comprising psicose according to claim 7 wherein the toothpaste is prepared by homogenization.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210156173.7A CN114432202A (en) | 2022-02-21 | 2022-02-21 | Toothpaste containing psicose and preparation method thereof |
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| CN202210156173.7A CN114432202A (en) | 2022-02-21 | 2022-02-21 | Toothpaste containing psicose and preparation method thereof |
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100166678A1 (en) * | 2006-11-10 | 2010-07-01 | Matsutani Chemical Industry Co., Ltd. | Noncarious material and anticarious agent containing rare sugar |
| CN103997913A (en) * | 2012-01-06 | 2014-08-20 | 松谷化学工业株式会社 | Sugar composition mainly composed of sucrose and D-psicose, and method for producing same |
| US20170028005A1 (en) * | 2014-01-30 | 2017-02-02 | NatGood IP, LLC | Natural sweetener |
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2022
- 2022-02-21 CN CN202210156173.7A patent/CN114432202A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20100166678A1 (en) * | 2006-11-10 | 2010-07-01 | Matsutani Chemical Industry Co., Ltd. | Noncarious material and anticarious agent containing rare sugar |
| CN103997913A (en) * | 2012-01-06 | 2014-08-20 | 松谷化学工业株式会社 | Sugar composition mainly composed of sucrose and D-psicose, and method for producing same |
| US20170028005A1 (en) * | 2014-01-30 | 2017-02-02 | NatGood IP, LLC | Natural sweetener |
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