CN114376763A

CN114376763A - Blood vessel support

Info

Publication number: CN114376763A
Application number: CN202111561248.1A
Authority: CN
Inventors: 吴雅莎; 尹玉杨; 李安伟
Original assignee: Hangzhou Wei Qiang Medical Technology Co ltd
Current assignee: Hangzhou Wei Qiang Medical Technology Co ltd
Priority date: 2021-12-16
Filing date: 2021-12-16
Publication date: 2022-04-22
Anticipated expiration: 2041-12-16
Also published as: CN114376763B

Abstract

The invention discloses a blood vessel stent, which comprises a main stent for reconstructing a main blood vessel and a branch stent for reconstructing a branch blood vessel. The main support comprises a main film and a main support framework fixed on the main film. The side wall of the main covering film is provided with a window with a preset shape. One end of the branch support is fixed on the inner wall of the main support, and the other end of the branch support penetrates through the window to be exposed out of the main support. The branch support is provided with a through opening. The opening is located the trunk support. The opening of the port is directed toward the proximal end of the main stent to allow blood in the main vessel to flow anteriorly into the branch vessel. By adopting the blood vessel support provided by the embodiment of the invention, the branch support is provided with the through hole positioned in the main support, and the opening of the through hole faces the near end of the main support, so that the blood flow in the main blood vessel can flow into the branch blood vessel in the forward direction, the blood supply efficiency of the forward blood flow of the branch blood vessel is increased, and the occurrence of diseases is avoided or reduced.

Description

Blood vessel support

Technical Field

The invention relates to the technical field of medical instruments, in particular to a vascular stent.

Background

Aortic Dissection (AD) refers to a state in which blood in the Aortic lumen enters the Aortic media from the Aortic intimal tear to separate the media, and expands along the major axis of the aorta to form true and false Aortic wall separation. Aortic dissection is a cardiovascular disease seriously threatening human life and health, the overall incidence rate is about 5/10 ten thousand, and the fatality rate is about 1.5/10 ten thousand. The morbidity and mortality of aortic dissection in China are far higher than those of European and American countries, and the aortic dissection is in a trend of youthfulness.

The Stanford typing method is a commonly used one of aortic dissection and is classified into two types, type a and type B. Wherein, Standford A type refers to the interlayer which is involved in ascending aorta and/or aortic arch; standford type B refers to a dissection restricted to the descending thoracic aorta. Standford type A dissections are currently primarily treated with traditional surgery because of the particular anatomy of the lesion site. The preferred treatment for the standard type B sandwich is intraluminal interventional Therapy (TEVAR).

The intracavity interventional therapy is mainly characterized in that a vascular stent is conveyed to a pathological change position by using a corresponding interventional instrument and then released, so that a dissection cut or an expanded cavity of a human blood vessel is separated, a true cavity of the blood vessel is remodeled, the blood flow is recovered to the correct flow direction, and the therapeutic effect is further achieved. The specific operation is that firstly, a surgical channel is established in a blood vessel by utilizing a guide wire replacement technology, then a conveying device carries a blood vessel stent into the blood vessel along the guide wire, the conveying device carries the blood vessel stent to a specified position under the traction of the guide wire, then a sheath tube in the conveying device releases the blood vessel stent to a lesion position to remold a blood vessel true cavity, the conveying device is withdrawn outwards after the blood vessel true cavity is remolded, and the operation is completed.

In patients receiving TEVAR, when the dissection involves the ascending aorta and/or aortic arch, the conventional stent graft may cover the branch vessels, affecting the blood supply of the important branch vessels of the aortic arch. Common methods for reconstructing branch blood vessels in cavities comprise chimney, windowing, branching technology and the like, while the incidence rates of internal leakage and stroke of the chimney technology in the operation period are respectively 21.6% and 7.8%, and the long-term implantation effect is poor; the windowing technology has high operation requirement, long learning period, long customizing period and high cost; the branch technology has good integrity and stable long-term implantation effect, and better conforms to the anatomical structure of the aortic arch. However, the existing modular branch technology has the problems that the blood supply of a branch blood vessel is influenced by the reverse blood flow of the embedded stent and the like.

Disclosure of Invention

In view of this, the present invention provides a blood vessel stent to solve the problem that the blood supply of a branch blood vessel is affected by the reverse blood flow of an embedded stent in the existing modular branch technology.

The embodiment of the invention provides a blood vessel support, which comprises a main support for reconstructing a main blood vessel and a branch support for reconstructing a branch blood vessel, wherein the main support comprises a main covering film and a main supporting framework fixed on the main covering film, a window with a preset shape is arranged on the side wall of the main covering film, one end of the branch support is fixed on the inner wall of the main support, the other end of the branch support penetrates through the window to be exposed out of the main support, a through hole is arranged on the branch support, the through hole is positioned in the main support, and the opening of the through hole faces to the near end of the main support, so that blood in the main blood vessel can flow into the branch blood vessel in the forward direction.

In some embodiments, the branch support comprises an embedded support and a reconstruction support, the embedded support is fixed on the inner wall of the main support, the reconstruction support is inserted into the embedded support, one end of the reconstruction support, far away from the embedded support, penetrates through the window and is exposed out of the main support, and the through hole is located on the reconstruction support and is exposed relative to the embedded support.

In some embodiments, the reconstruction stent includes a distal segment located at a distal end of the reconstruction stent, a proximal segment located at a proximal end of the reconstruction stent, and a bending segment connecting the proximal segment and the distal segment, the through hole is opened on the bending segment, and the through hole is disposed on a side of the bending segment near a central axis of the main stent.

In some embodiments, the through opening is located at a central position of the bending section; or the through hole is positioned at a position eccentric to the central position of the bending section.

In some embodiments, the inner stent is a tubular structure, the proximal end of the inner stent is opened with an opening communicating with the inner cavity of the inner stent, and the outer diameter of the reconstruction stent is larger than the inner diameter of the inner stent, so that the reconstruction stent seals the opening at the proximal end of the inner stent.

In some embodiments, the outer diameter of the reconstruction scaffold is greater than the maximum outer diameter of the window such that the reconstruction scaffold seals the window.

In some embodiments, the reconstruction scaffold is configured as a constant diameter structure.

In some embodiments, the reconstruction scaffold is configured as a non-isodiametric structure.

In some embodiments, the outer diameter of the reconstruction stent gradually increases from the proximal end of the reconstruction stent towards the distal end; or the outer diameters of the reconstruction bracket gradually increase from the middle part of the reconstruction bracket to the directions of the two end parts respectively; or the outer diameter of the part of the reconstruction bracket, which is positioned in the main bracket, is kept unchanged, and the outer diameter of the part of the reconstruction bracket, which is positioned outside the main bracket, is gradually increased from one end close to the window to one end far away from the window.

In some embodiments, the predetermined shape is a circle or an ellipse. The oval window design is more in line with the vascular structure of the human body, the fault-tolerant rate is high, the tightness of the vascular stent with the window structure is improved, and internal leakage is effectively prevented.

In some embodiments, the proximal end of the inline mount is located below the window; alternatively, the proximal end of the inline mount is flush with the distal edge of the window.

In some embodiments, the distal end of the embedded stent is provided with an oblique opening facing the central axis of the main stent, and a distance between the distal end of the oblique opening and the central axis of the main stent is greater than a distance between the proximal end of the oblique opening and the central axis of the main stent. The inclined opening design of the embedded bracket is beneficial to avoiding the stress concentration on a plane when the far end of the embedded bracket is contracted in the conveying device, and is beneficial to reducing the release resistance of the intravascular bracket.

In some embodiments, the embedded stent includes an embedded graft and an embedded support scaffold secured to the embedded graft, the embedded support scaffold including at least one support rod configured in an open loop configuration. The waveform supporting rod on the embedded bracket is set to be an open-loop structure, so that the release resistance of the blood vessel bracket is further reduced.

In some embodiments, the at least one support rod is disposed on a side wall of the embedded film close to the central axis of the main stent, and a side wall of the embedded film far from the at least one support rod is attached to a wall of the inner cavity of the main stent.

In some embodiments, a fixing member is disposed on the embedded bracket, and a mating member for mating with the fixing member is disposed on the reconstruction bracket.

In some embodiments, the fastener is an anchoring ring, and the mating member is an anchoring hook that is cooperatively fastened with the anchoring ring; or, the fixing piece is an anchoring hook, and the matching piece is an anchoring ring matched and fixed with the anchoring hook. The embedded support and the rebuilt support are fixed through the cooperation of the anchoring ring and the anchoring hook, so that the migration of the branch support is effectively avoided, and the internal leakage is further effectively prevented.

In some embodiments, the fastener is disposed on an inner sidewall of the inline holder; the mating member is disposed at a distal end of the reconstruction bracket.

In some embodiments, the engaging member is disposed corresponding to the fixing member; the quantity of mounting is including a plurality of, and is a plurality of the mounting certainly embedded support's axis is the symmetric distribution setting.

In some embodiments, the developing device further comprises a developing positioning member disposed on at least one of the distal end of the embedded bracket, the fixing member, and the mating member.

The vascular stent provided by the embodiment of the invention comprises a main stent and branch stents, wherein a window with a preset shape is formed on the side wall of a main covering film of the main stent, so that one end of the branch stent is fixed on the inner wall of the main stent, the other end of the branch stent penetrates through the window to expose the main stent, a through hole positioned in the main stent is formed in the branch stent, and the opening of the through hole faces to the near end of the main stent, so that blood flow in the main stent can flow into the branch vessels in the forward direction, the blood supply amount and the blood supply efficiency of the forward blood flow of the branch vessels are improved, and the occurrence of diseases is favorably avoided or reduced.

Drawings

In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to these drawings without creative efforts.

Fig. 1 is a structural schematic diagram of a blood vessel stent provided by an embodiment of the invention in a deployment state.

Fig. 2 is a first view structural diagram of the main stent and the embedded stent of the blood vessel stent in fig. 1.

Fig. 3 is a structural diagram of a main stent and an embedded stent of the blood vessel stent in fig. 2 from a second view angle.

Fig. 4 is an enlarged view of a reconstructed stent of the vascular stent of fig. 1.

Fig. 5 is an enlarged view of an inline stent of the vascular stent of fig. 3.

Reference numerals: 100. a vascular stent; 10. a trunk support; 12. covering a film on the trunk; 14. a trunk support skeleton; 141. a wave-shaped support rod; 101. a window; 20. a branch support; 30. embedding a bracket; 301. an oblique opening; 302. an opening; 31. a developing positioning member; 32. embedding a film; 34. a supporting framework is embedded; 341. a wave-shaped support rod; 36. a fixing member; 50. reconstructing a stent; 501. a port; 51. a proximal segment; 52. branch film covering; 53. a distal segment; 54. a branch supporting framework; 541. a wave-shaped support rod; 55. bending the section; 56. a fitting member.

Detailed Description

The technical solutions in the embodiments of the present application will be clearly and completely described below with reference to the drawings in the embodiments of the present application, and it is obvious that the described embodiments are only a part of the embodiments of the present application, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present application.

For the blood vessel stent, the proximal end refers to the end of the blood vessel stent close to the heart of the human body after the blood vessel stent is used for interventional therapy, and the distal end refers to the end of the blood vessel stent far away from the heart of the human body after the blood vessel stent is used for interventional therapy. It is understood that the terminology used in the description and claims of the present application and the accompanying drawings is for the purpose of describing particular embodiments only and is not intended to be limiting of the present application. The terms "first," "second," and the like in the description and claims of the present application and in the above-described drawings are used for distinguishing between different objects and not for describing a particular order. The singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. The term "comprises" and any variations thereof is intended to cover non-exclusive inclusions. Further, the present application may be embodied in many different forms and is not limited to the embodiments described in the present embodiment. The following detailed description is provided for the purpose of providing a more thorough understanding of the present disclosure, and the words used to indicate orientation above, below, left and right are used solely to describe the illustrated structure in the context of the corresponding figures.

While the specification concludes with claims describing preferred embodiments of the present application, it is to be understood that the above description is made only for the purpose of illustrating the general principles of the present application and is not intended to limit the scope of the present application. The protection scope of the present application shall be subject to the definitions of the appended claims.

Referring to fig. 1, fig. 1 is a schematic structural diagram of a stent 100 according to an embodiment of the present disclosure. The vascular stent 100 includes a main stent 10 for reconstructing a main blood vessel and a branch stent 20 for reconstructing a branch blood vessel. The main stent 10 includes a main covering film 12 and a main supporting skeleton 14 fixed on the main covering film 12. A window 101 with a preset shape is opened on the side wall of the main covering film 12. One end of the branch stent 20 is fixed to the inner wall of the main stent 10. The other end of the branch stent 20 passes through the window 101 to be exposed out of the main stent 10. The branch support 20 is provided with a through opening 501, and the through opening 501 is located in the main support 10. The opening 501 opens towards the proximal end of the main stent 10 to allow blood in the main vessel to flow anteriorly into the branch vessels. The branch stent 20 can be communicated with the main stent 10 through the through opening 501, so that the blood flow in the main blood vessel can flow to the branch blood vessel in the forward direction, the blood supply efficiency of the branch blood vessel is increased, and the occurrence of diseases is avoided or reduced.

It should be understood by those skilled in the art that the illustrated fig. 1 is merely an example of the vascular stent 100 and does not constitute a limitation of the vascular stent 100, and the vascular stent 100 may include more or less components than those illustrated in fig. 1, or some components may be combined, or different components, for example, the vascular stent 100 may further include a drug coating or the like for treating diseased tissue of the vasculature.

The main stent 10 and the branch stents 20 are both self-expandable stents that can be radially expanded and contracted. When the main stent 10 or the branch stent 20 is delivered through the sheath, the diameter of the main stent 10 or the branch stent 20 may be contracted to a smaller state for delivery in the sheath. When the main stent 10 or the branch stent 20 is released in a blood vessel, the main stent 10 or the branch stent 20 can automatically expand to a required shape and size, so that the main stent 10 can be supported on the inner wall of a lesion position of the main blood vessel, thereby reconstructing the main blood vessel, and the branch stent 20 generates a radial supporting effect on the inner wall of the branch blood vessel, thereby reconstructing the branch blood vessel, so that blood flow in the main blood vessel flows into the branch stent 20 for reconstructing the branch blood vessel.

Referring to fig. 2 and fig. 3 together, fig. 2 is a schematic structural diagram of a main stent 10 and an embedded stent 30 of the blood vessel stent 100 in fig. 1 from a first view angle; fig. 3 is a structural diagram of the main stent 10 and the embedded stent 30 of the blood vessel stent 100 in fig. 2 from a second viewing angle. The main stent 10 may be constructed in a constant diameter tubular structure, i.e., the main stent 10 is a cylindrical tubular structure with a constant radial dimension. The main stent 10 may also be configured as a non-constant diameter tubular structure, i.e., the main stent 10 is a conical tubular structure or a frustum-shaped tubular structure with a diameter that varies from the distal end to the proximal end. The shape of the cross section of the main stent 10 is circular or elliptical to achieve the matching of the shape of the main stent 10 with the shape of the blood vessel. The trunk support frame 14 includes a plurality of corrugated support rods 141 arranged at intervals in the axial direction of the trunk coating film 12. Each of the plurality of wave-shaped supporting rods 142 is formed by surrounding a plurality of zigzag structures or a plurality of sine wave-shaped structures. Each of the wave-shaped support rods 142 may be a high-wave annular support rod or a low-wave annular support rod. The equal-height wave annular support rods mean that the heights of all wave crests on the wave-shaped support rods 142 are the same, and the heights of all wave troughs are also the same, that is, all wave crests and all wave troughs are respectively on the same plane. The high-low wave annular support rods mean that the heights of all wave crests on the waveform support rod 142 are different, that is, the heights of all wave troughs can also be different. The wave support rods 142 may be configured in a closed loop configuration or an open loop configuration. Optionally, the corrugated supporting rods 142 are configured to be an open-loop structure, each corrugated supporting rod 142 is provided with a connecting sleeve, the connecting sleeves connect two opposite ends of the corrugated supporting rod 142, that is, the two opposite ends of the corrugated supporting rod 142 are all accommodated in the connecting sleeves, and then the two ends of the nickel-titanium wire are fixed inside the connecting sleeves through mechanical compression or welding.

The material of the main covering film 12 includes, but is not limited to, at least one of Polyethylene terephthalate (PET), Polytetrafluoroethylene (PTFE), Thermoplastic polyurethane elastomer rubber (TPU), silicone rubber, Polyvinyl alcohol (PVA), hydrogel, expanded polytetrafluoroethylene, Polyethylene, high-density Polyethylene, Polyethylene terephthalate, and other polymer materials. The backbone support armature 14 may be laser cut from a material having a shape memory effect; alternatively, it may be woven from a filamentary material having a shape memory effect. Materials having a shape memory effect include, but are not limited to, at least one of stainless steel, tungsten alloys, cobalt-chromium alloys, and nickel-titanium alloys. In the present embodiment, each of the corrugated support rods 142 is braided from one or more strands of nickel titanium wire. When the main stent 10 is transported through the sheath, the diameter of the main supporting skeleton 14 can be contracted to a smaller state for transportation in the sheath; when the main support scaffold 14 is released within the blood vessel, the main support scaffold 14 can automatically expand to a desired shape and size so that the main support scaffold 14 can be supported on the inner wall of the corresponding blood vessel. In some embodiments, the backbone support armature 14 may be sewn to the backbone covering film 12 by sutures, i.e., sutures may follow the undulating course of each undulating support bar 142 along the entire backbone support armature 14. The suture can also be formed by sewing each of the plurality of wave-shaped support rods 142 to the main covering film 12 through a plurality of sewing knots which are distributed at unequal intervals. In other embodiments, the main supporting framework 14 may be fixed on the main covering film 12 by other fixing methods such as bonding, hot pressing, and the like.

Referring to fig. 1 and 4 together, fig. 4 is an enlarged view of a reconstruction stent 50 of the vascular stent 100 of fig. 1. The bifurcation stent 20 includes an inline stent 30 and a reconstruction stent 50. In this embodiment, the reconstruction stent 50 is detachably fixed to the inline stent 30, thereby facilitating the delivery or release of the main stent 10 and the branch stents 20 to the blood vessel of the vasculature to be reconstructed. In some embodiments, the rebuild support 50 may also be integrally formed with the inset support 30, thereby ensuring the reliability and stability of the connection between the rebuild support 50 and the inset support 30. In this embodiment, the inline holder 30 is fixed to the inner wall of the trunk holder 10. The reconstruction bracket 50 is inserted into the inline bracket 30 so that the inline bracket 30 can wrap the outer circumferential surface of the proximal end of the reconstruction bracket 50, thereby effectively preventing the inner leakage. The end of the reconstruction bracket 50 remote from the inline bracket 30 is exposed out of the main bracket 10 through the window 101. Specifically, the reconstruction stent 50 includes opposite proximal and distal ends, the proximal end of the reconstruction stent 50 is fixedly connected to the inline stent 30, and the distal end of the reconstruction stent 50 extends out of the window 101 to expose the main stent 10. The through opening 501 is located on the reconstruction stent 50 and exposed with respect to the inner insert stent 30, thereby facilitating blood flow in the main stent 10 to flow in the forward direction toward the branch stent 20 for reconstructing the branch vessel.

The reconstruction stent 50 is constructed as a hollow tubular structure to achieve communication between the reconstruction stent 50 and the inline stent 30. The reconstruction stent 50 includes a distal section 51 at the distal end of the reconstruction stent 50, a proximal section 53 at the proximal end of the reconstruction stent 50, and a bend section 55 connecting the proximal section 51 and the distal section 53. Opening 501 is opened on bending section 55, and opening 501 sets up in bending section 55 and is close to the one side of the axis of main support 10. Optionally, the through opening 501 is located at the center of the bending section 55, so that the blood flow in the main stent 10 can flow more forward to the branch stent 20 for reconstructing the branch vessel. In other embodiments, the through opening 501 is located off-center from the center of the bend segment 55. It should be noted that the central position of the bending segment 55 refers to the position where the reconstruction bracket 50 is bent along the bending line.

Optionally, the corrugated struts 541 of the reconstruction stent 50 are less dense in the inflection segments 55 than in the distal and

proximal segments

51, 53. Specifically, the distance between two adjacent corrugated supporting rods 541 on the bending section 55 is greater than the distance between two adjacent corrugated supporting rods 541 on the distal section 51 and the proximal section 53, so as to increase the occupied space of the through opening 501, and further, the blood flow in the main stent 10 can flow forward more toward the branch stent 20 for reconstructing the branch vessel. The wave crests and the wave troughs of the two adjacent wave-shaped supporting rods 541 on the bending section 55 are arranged in a staggered manner, that is, the wave crest of one wave-shaped supporting rod 541 is opposite to the wave trough of the other wave-shaped supporting rod 541, so that the occupied space of the through opening 501 is further increased. The shape of the through opening 501 may be, but is not limited to, a regular or irregular shape such as a rectangle, a circle, an ellipse, a trapezoid, etc. In this embodiment, the through openings 501 are rectangular in shape, and the extending direction of the through openings 501 is parallel to the extending direction of the reconstruction stent 50 to further increase the blood flow to the reconstruction stent 50.

The cross section of the branch stent 20 is circular or elliptical, that is, the embedded stent 30 and the reconstruction stent 50 are both constructed as tubular structures, so as to match the shape of the branch stent 20 with the shape of the branch vessel. The preset shape is an ellipse, so that the design of the window 101 is more in line with the structure of the blood vessel of the human body, the fault tolerance rate is high, the problem of tightness between the branch stent 20 and the window 101 is solved, and the angles of the reconstruction stent 50 and the main stent 10 are conveniently changed to adapt to various blood vessel shapes. In some embodiments, the predetermined shape may also be a circle, a diamond hole, an irregular curved surface, or the like, and the present application is not limited specifically.

Both the inline stent 30 and the reconstructive stent 50 are self-expanding stents that are radially expandable and contractible. Optionally, the outer diameter of the reconstruction bracket 50 is larger than the maximum outer diameter of the window 101, so that the reconstruction bracket 50 seals the window 101, thereby effectively preventing the main bracket 10 from leaking inwards at the window 101. The embedded bracket 30 is of a tubular structure, the proximal end of the embedded bracket 30 is provided with an opening 302 communicated with the inner cavity of the embedded bracket 30, and the outer diameter of the reconstruction bracket 50 is larger than the inner diameter of the embedded bracket 30, so that the reconstruction bracket 50 seals the opening 302 at the proximal end of the embedded bracket 30, the firmness of connection between the reconstruction bracket 50 and the embedded bracket 30 is enhanced, and internal leakage can be effectively prevented.

The reconstruction stent 50 may be configured in either a constant diameter configuration or a non-constant diameter configuration. In the present embodiment, the rebuilding support 50 is configured as a non-equal diameter structure to better realize the sealing connection of the rebuilding support 50 with the main support 10 and the embedded support 30, thereby achieving a better leakage-proof effect. Wherein, the outer diameter of the reconstruction bracket 50 gradually increases from the near end of the reconstruction bracket 50 to the far end, that is, the reconstruction bracket 50 is trumpet-shaped; or, the outer diameter of the rebuilding support 50 gradually increases from the middle of the rebuilding support 50 towards the direction of the two end portions, that is, the rebuilding support 50 is dumbbell-shaped; alternatively, the outer diameter of the portion of the reconstruction stent 50 located inside the main stent 10 is kept constant, and the outer diameter of the portion of the reconstruction stent 50 located outside the main stent 10 is gradually increased from the end close to the window 101 to the end far from the window 101.

The reconstruction stent 50 includes a branch graft 52 and a branch support scaffold 54 fixed to the branch graft 52. The branch supporting framework 54 comprises at least one wave-shaped supporting rod 541, so that the supporting strength of the reconstruction stent 50 can be increased, and the consequence that the accessed reconstruction stent 50 is pressed by the main stent 10 to cause unsmooth blood flow and even blockage can be prevented. The structure, shape and material of the branch cover film 52 and the branch support skeleton 54 are similar to those of the main cover film 12 and the main support skeleton 14, and thus are not described in detail herein.

Referring to fig. 1, 3 and 5 together, fig. 5 is an enlarged view of the inline stent 30 of the vascular stent 100 of fig. 3. Optionally, the embedded stent 30 is disposed in a staggered manner with respect to the window 101, that is, the embedded stent 30 does not cover the window 101, so that the reconstruction stent 50 forms a bending section 55 near the window 101, and thus the branch stent 20 can open a through hole 501 at the bending section 55, so that blood flowing in the main stent 10 flows in a forward direction to the branch stent 20 for reconstructing a branch blood vessel, thereby increasing blood supply efficiency of the forward blood flowing in the branch blood vessel and avoiding or reducing occurrence of a disease. In this embodiment, the proximal end of the inline holder 30 is located below the window 101. Specifically, the distal edge of the window 101 is spaced from the proximal end of the inline holder 30, i.e., the inline holder 30 extends from a lower edge relatively close to the window 101 toward the distal end of the main holder 10. Wherein, in the orthographic projection direction perpendicular to the central axis of the main support 10, the projection of the window 101 and the projection of the embedded support 30 are staggered.

In other embodiments, the proximal end of the inline mount 30 is flush with the distal edge of the window 101. Wherein the distal edge of the window 101 is arranged adjacent to the proximal end of the inline holder 30, i.e. the inline holder 30 extends from the window 101 towards the proximal end of the main holder 10. Wherein, in the orthographic projection direction perpendicular to the central axis of the main support 10, the projection of the window 101 is adjacently arranged to the projection of the embedded support 30.

In some embodiments, the distal end of the inline holder 30 is provided with a developing positioning member 31. When the rebuilding bracket 50 needs to be connected to the embedded bracket 30, the position of the developing positioning member 31 can be clearly observed through the imaging device, thereby facilitating the assembly of the rebuilding bracket 50 and the embedded bracket 30. In other embodiments, the proximal end of the inline holder 30 may also be provided with a developer positioning member 31. The developing positioning member 31 is made of a radiopaque material. The radiopaque material is preferably a noble metal material such as gold, platinum or tantalum. The developing positioning member 31 may take various forms such as a ring, a thread, a band, or a dot, and is fixed to the distal end of the embedded bracket 30 by sewing, punching, embedding, heat fusing, bonding, welding, or caulking, which are techniques commonly used in the art. In some embodiments, the developing positioning member 31 may be annular, and the developing positioning member 31 is sleeved outside the distal end of the embedded bracket 30; alternatively, the developing spacer 31 is embedded in the distal end face of the embedding bracket 30.

The inline holder 30 is constructed in a hollow tubular structure. Optionally, the distal end of the embedded stent 30 is opened with an oblique opening 301, the oblique opening 301 faces the central axis of the main stent 10, and a distance between the distal end of the oblique opening 301 and the central axis of the main stent 10 is greater than a distance between the proximal end of the oblique opening 301 and the central axis of the main stent 10. The inclined opening 301 is beneficial to avoiding the stress concentration on a plane when the distal end of the embedded stent 30 is contracted in the sheath, thereby effectively reducing the release resistance of the intravascular stent 10 and improving the smoothness of the intravascular stent 10 when the intravascular stent 10 is released in a blood vessel.

The central axis of the embedded bracket 30 is parallel to or intersects with the central axis of the main bracket 10. In the present embodiment, the central axis of the recessed stent 30 is substantially parallel to the central axis of the main stent 10, that is, an included angle between the central axis of the recessed stent 30 and the central axis of the main stent 10 is substantially 0 degree.

The embedded stent 30 includes an embedded graft 32 and an embedded support scaffold 34 secured to the embedded graft 32. The embedded supporting framework 34 comprises at least one wave-shaped supporting rod 341, so that the supporting strength of the embedded stent 30 can be increased, and the consequence that the accessed reconstruction stent 50 is blocked even due to unsmooth blood flow caused by the compression of the main stent 10 is prevented. The structure, shape and material of the embedded cover film 32 and the embedded support skeleton 34 are similar to those of the main cover film 12 and the main support skeleton 14, and thus are not described in detail herein. Except that some or all of the wave shaped support rods 341 are constructed in an open loop structure. The distance between the opposite ends of each of the waveform supporting rods 341 is greater than the preset distance, thereby solving the problem of large release resistance of the stent 10 and further improving the smoothness of the stent 10 when released in a blood vessel. Wherein, the two opposite ends of each supporting rod 341 are abutted against or spaced from the inner cavity wall of the main frame 10.

Specifically, the at least one corrugated supporting rod 341 is disposed on a sidewall of the embedded film 32 close to the center line of the main support 10, and a sidewall of the embedded film 32 far from the at least one supporting rod 341 is attached to the inner cavity wall of the main support 10. Because the part of the embedded coating 32 not covered by the at least one wave-shaped supporting rod 341 is attached to the inner cavity wall of the main support 10, the connecting area between the main support 10 and the embedded support 30 is increased, and the reliability and the stability of the connection between the embedded support 30 and the main support 10 are ensured while the support performance of the embedded supporting framework 34 is ensured.

Specifically, when the number of the wave shaped support rods 341 is one, the wave shaped support rods 341 are configured in an open loop structure. In the present embodiment, the embedded supporting skeleton 34 includes a plurality of waveform supporting rods 341. A plurality of corrugated support rods 341 are provided at intervals in the axial direction of the inline holder 30. The number of the plurality of wave shaped support rods 341 is 2, and each wave shaped support rod 341 is configured in an open loop structure. It should be noted that the number of the waveform supporting rods 341 may be designed according to the specification of the embedded stent 30, and the number of the waveform supporting rods 341 may also be 1 or more than 2, which is not specifically limited in the present application.

Optionally, in some embodiments, the fixing member 36 is disposed on the recessed bracket 30, and the mating member 57 for mating with the fixing member 26 is disposed on the reconstruction bracket 50, so as to prevent the reconstruction bracket 50 from shifting in the recessed bracket 30, thereby improving the reliability and stability of the connection between the reconstruction bracket 50 and the recessed bracket 30, and ensuring that the opening direction of the through hole 501 always faces the blood flow direction in the main vessel. In this embodiment, the fastener 36 is an anchoring loop and the mating element 56 is an anchoring hook that is secured in engagement with the anchoring loop. In some embodiments, the fastener 36 is an anchoring hook and the mating element 56 is an anchoring loop that is cooperatively secured with the anchoring hook.

Optionally, the fixing element 36 is disposed on an inner sidewall of the recessed bracket 30, and the engaging element 56 is disposed at a distal end of the rebuilding bracket 50, so that when the rebuilding bracket 50 is inserted into the recessed bracket 30, the fixing element 36 can be conveniently anchored to the engaging element 56, so as to achieve the fixed connection of the rebuilding bracket 50 to the recessed bracket 30. The engaging member 56 is disposed in correspondence with the fixing member 36. The number of the fixing members 36 includes a plurality of fixing members 36, and the plurality of fixing members 36 are symmetrically distributed from the center line of the embedded bracket 30, so that the reliability and the stability of the connection between the rebuilding bracket 50 and the embedded bracket 30 are further improved.

At least one of the fixing member 36 and the fitting member 56 is also provided with the developing positioning member 31, so that the inserting positioning between the rebuilding bracket 50 and the embedded bracket 30 is conveniently and quickly realized. In some embodiments, the developing positioning member 31 is fixedly connected to the fixing member 36 and the fitting member 56 independently of the fixing member 36 and the fitting member 56. In some embodiments, the fixing member 36 and the fitting member 56 are integrally formed with the developing positioning member 31. For example, the fastener 36 and the engagement member 56 are both made of radiopaque material; alternatively, the outer surfaces of the fixing member 36 and the fitting member 56 may be formed with a development positioning layer by spraying, dipping, or the like, wherein the development positioning layer comprises a radiopaque material.

The intravascular stent provided by the embodiment of the invention has at least one of the following beneficial effects:

1. the vascular stent comprises a main stent and branch stents, wherein a window with a preset shape is formed in the side wall of a main coating film of the main stent, so that one end of the branch stent is fixed on the inner wall of the main stent, the other end of the branch stent penetrates through the window to expose the main stent, a through hole positioned in the main stent is formed in the branch stent, and the opening of the through hole faces to the near end of the main stent, so that blood flow in the main stent can flow into the branch vessels in a forward direction, the blood supply amount and the blood supply efficiency of the forward blood flow of the branch vessels are improved, and the occurrence of diseases is favorably avoided or reduced;

2. the preset oval window design is more in line with the vascular structure of the human body, the fault tolerance rate is high, the sealing performance of the vascular stent with the window structure is improved, and internal leakage is effectively prevented;

3. the inclined opening design of the embedded bracket is beneficial to avoiding the stress concentration on a plane when the far end of the embedded bracket is contracted in the conveying device, and is beneficial to reducing the release resistance of the intravascular bracket;

4. the waveform supporting rod on the embedded stent is arranged into an open-loop structure, so that the release resistance of the intravascular stent is further reduced;

5. the embedded support and the rebuilt support are fixed through the cooperation of the anchoring ring and the anchoring hook, so that the migration of the branch support is effectively avoided, and the internal leakage is further effectively prevented.

The above embodiments of the present invention are described in detail, and the principle and the implementation of the present invention are explained by applying specific embodiments, and the above description of the embodiments is only used to help understanding the method of the present invention and the core idea thereof; meanwhile, for a person skilled in the art, according to the idea of the present invention, there may be variations in the specific embodiments and the application scope, and in view of the above, the content of the present specification should not be construed as a limitation to the present invention.

Claims

1. The utility model provides a vascular support, its characterized in that, is including being used for rebuilding trunk vascular trunk support and the branch's support that is used for rebuilding branch's vascular, trunk support includes the trunk tectorial membrane and is fixed in trunk supporting framework on the trunk tectorial membrane, set up the window of predetermineeing the shape on the lateral wall of trunk tectorial membrane, the one end of branch's support is fixed in on the inner wall of trunk support, the other end of branch's support passes the window and exposes outward trunk support, the opening has been seted up on the branch's support, the opening is located in the trunk support, the opening orientation of opening the near-end of trunk support, so that blood in the trunk blood vessel can the cisoid flow in branch's vascular.

2. The vessel support according to claim 1, wherein the branch support comprises an embedded support and a reconstruction support, the embedded support is fixed on the inner wall of the main support, the reconstruction support is inserted into the embedded support, one end of the reconstruction support far away from the embedded support penetrates through the window to expose out of the main support, and the through hole is positioned on the reconstruction support and exposed relative to the embedded support.

3. The vessel stent of claim 2, wherein the reconstruction stent comprises a distal section located at the distal end of the reconstruction stent, a proximal section located at the proximal end of the reconstruction stent, and a bending section connecting the proximal section and the distal section, the through openings are formed in the bending section, and the through openings are formed on one side of the bending section close to the central axis of the main stent.

4. The stent according to claim 3, wherein the through opening is located at a central position of the bent section; or the through hole is positioned at a position eccentric to the central position of the bending section.

5. The vessel stent of claim 2, wherein the stent-graft is a tubular structure, the proximal end of the stent-graft is provided with an opening communicating with the lumen of the stent-graft, and the outer diameter of the stent-graft is larger than the inner diameter of the stent-graft so that the stent-graft seals the opening at the proximal end of the stent-graft.

6. The vascular stent of claim 2, wherein the outer diameter of the reconstruction stent is greater than the maximum outer diameter of the window such that the reconstruction stent seals the window.

7. The vascular stent of claim 2, wherein the reconstruction stent is configured in a constant diameter configuration.

8. The vascular stent of claim 2, wherein the reconstruction stent is configured as a non-isodiametric structure.

9. The vascular stent of claim 8, wherein the outer diameter of the reconstruction stent gradually increases from the proximal end of the reconstruction stent towards the distal end; or the outer diameters of the reconstruction bracket gradually increase from the middle part of the reconstruction bracket to the directions of the two end parts respectively; or the outer diameter of the part of the reconstruction bracket, which is positioned in the main bracket, is kept unchanged, and the outer diameter of the part of the reconstruction bracket, which is positioned outside the main bracket, is gradually increased from one end close to the window to one end far away from the window.

10. The vascular stent of claim 1, wherein the predetermined shape is a circle or an ellipse.

11. The vascular stent of claim 2, wherein the proximal end of the inline stent is located below the window; alternatively, the proximal end of the inline mount is flush with the distal edge of the window.

12. The vessel support according to claim 2, wherein the distal end of the embedded stent is provided with an oblique opening facing the central axis of the main stent, and the distance between the distal end of the oblique opening and the central axis of the main stent is greater than the distance between the proximal end of the oblique opening and the central axis of the main stent.

13. The vascular stent of claim 2, wherein the embedded stent comprises an embedded graft and an embedded support scaffold secured to the embedded graft, the embedded support scaffold comprising at least one support strut configured in an open loop configuration.

14. The vessel stent of claim 13, wherein the at least one supporting rod is disposed on a sidewall of the embedded film close to the central axis of the main stent, and a sidewall of the embedded film away from the at least one supporting rod is attached to a lumen wall of the main stent.

15. The blood vessel support of claim 2, wherein the embedded support is provided with a fixing member, and the reconstruction support is provided with a matching member matched and fixed with the fixing member.

16. The vascular stent of claim 15, wherein the securing element is an anchoring loop and the mating element is an anchoring hook that mates with the anchoring loop; or, the fixing piece is an anchoring hook, and the matching piece is an anchoring ring matched and fixed with the anchoring hook.

17. The vascular stent of claim 15, wherein the anchor is disposed on an interior sidewall of the inline stent; the mating member is disposed at a distal end of the reconstruction bracket.

18. The vascular stent of claim 15, wherein the engagement elements are disposed in correspondence with the securing elements; the quantity of mounting is including a plurality of, and is a plurality of the mounting certainly embedded support's axis is the symmetric distribution setting.

19. The vascular stent of claim 15, further comprising a visualization positioning member disposed on at least one of the distal end of the inline stent, the securing member, and the mating member.