CN114366289A - Microwave ablation antenna and manufacturing method - Google Patents
Microwave ablation antenna and manufacturing method Download PDFInfo
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- CN114366289A CN114366289A CN202210040421.1A CN202210040421A CN114366289A CN 114366289 A CN114366289 A CN 114366289A CN 202210040421 A CN202210040421 A CN 202210040421A CN 114366289 A CN114366289 A CN 114366289A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B2018/00005—Cooling or heating of the probe or tissue immediately surrounding the probe
- A61B2018/00011—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids
- A61B2018/00023—Cooling or heating of the probe or tissue immediately surrounding the probe with fluids closed, i.e. without wound contact by the fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
- A61B18/18—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves
- A61B18/1815—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves
- A61B2018/183—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by applying electromagnetic radiation, e.g. microwaves using microwaves characterised by the type of antenna
Abstract
The invention relates to a microwave ablation antenna and a manufacturing method thereof, wherein the antenna comprises a needle head, a coaxial cable, a non-metal sleeve fixed behind the needle head and a hollow separation cylinder arranged in the non-metal sleeve, inner radiating bodies electrically connected with an inner conductor of the coaxial cable are arranged on the inner walls of the needle head and the non-metal sleeve, an outer radiating body electrically connected with an outer conductor of the coaxial cable is arranged on the outer wall of the non-metal sleeve, an inner insulating layer is coated on the inner wall of the inner radiating body, a gap between the inner insulating layer and the separation cylinder is used as a water return channel of cooling water and is connected with a water outlet arranged on the antenna, and the inner part of the hollow separation cylinder is used as a water inlet channel of the cooling water and is connected with a water inlet arranged on the antenna. The invention has simple structure, uses the hollow pointed structure to replace part of coaxial cables, has good ablation shape, lower needle temperature, small damage to normal tissue cells and obvious treatment effect, and has very important use value in the field of microwave treatment.
Description
Technical Field
The invention relates to a medical instrument for microwave ablation treatment, belonging to the field of medical microwave technology application.
Background
The microwave ablation technology is a technology that a microwave ablation needle is punctured to a target tumor under the guidance of an imaging technology, and tumor cells in a patient body are eradicated or basically killed in a microwave heating mode. Microwave energy is radiated into biological tissues through an ablation needle, ions and polar molecules in the tissues rotate at a high speed and collide with each other under the action of high-frequency alternating energy, and the temperature rises to 65-100 ℃ in a short time. The temperature and the maintenance time are the key for judging the inactivation of the tumor. Research shows that when the temperature is 42-45 ℃, the sensitivity of tumor tissues to chemotherapy and radiotherapy is increased. When the temperature reaches 50-55 ℃ and lasts for 4-6 min, the tumor tissue will have coagulation necrosis. When the temperature exceeds 60 ℃, the tumor tissue can be immediately coagulated and necrotized. If the temperature exceeds 100 ℃, vaporization or carbonization may occur.
In recent years, the application of microwave ablation technology in clinical practice is becoming more and more widespread, especially in the field of cancer treatment such as liver tumor and kidney tumor. Microwave ablation presents fewer complications and trauma to the patient than traditional surgical resection. Therefore, the microwave ablation technology is considered to be another effective malignant tumor treatment mode after surgery, chemotherapy, radiotherapy and immunotherapy, and the clinical application popularization rate is higher and higher.
At present, the microwave ablation antenna for clinical application has some problems and disadvantages: 1. the front end of the microwave ablation antenna has overhigh working temperature and is easy to damage normal tissues; 2. the microwave ablation antenna has an out-of-round ablation shape, and the precise treatment of the tumor is difficult to ensure in the operation process.
Disclosure of Invention
The invention provides a microwave ablation antenna and a manufacturing method thereof, the microwave ablation antenna is simple in structure, a hollow pointed structure is used for replacing part of coaxial cables, the ablation shape is good, the temperature of a needle head is low, the damage to normal tissue cells is small, the treatment effect is obvious, and the microwave ablation antenna has very important use value in the field of microwave treatment.
The technical scheme adopted by the invention for solving the technical problems is as follows: the utility model provides a microwave ablation antenna, includes syringe needle and coaxial cable, its characterized in that still includes: the non-metal sleeve that is fixed in the syringe needle rear separates a section of thick bamboo with the cavity of locating in the non-metal sleeve, and syringe needle and non-metal sleeve inner wall are equipped with the interior irradiator of being connected with the coaxial cable inner conductor electricity, and non-metal sleeve's outer wall is equipped with the outer irradiator of being connected with the coaxial cable outer conductor electricity, the inner wall coating of interior irradiator has the internal insulation layer, and the internal insulation layer with separate the clearance between a section of thick bamboo and regard as the return water course of cooling water to with set up to be connected in the delivery port of antenna, the cavity separates the inside of a section of thick bamboo and regards as the inlet channel of cooling water, and with set up to be connected in the water inlet of antenna.
Further, an outer insulating layer is arranged on the outer wall of the outer radiating body.
Furthermore, the non-metal sleeve is composed of a tubular part and a base, and the water outlet and the water inlet are fixed on the base.
Furthermore, the inner surface and the outer surface of the needle head are both conical structures.
Furthermore, the outer surface of the needle head is of a conical structure, the inner surface of the needle head is of a concave spherical surface, and the front part of the non-metal sleeve is provided with a convex part embedded into the concave spherical surface.
Furthermore, the inner wall of the front part of the non-metal sleeve (2) is sequentially provided with an inner radiator (21) and an inner insulating layer (23).
In addition, the invention also provides a manufacturing method of the microwave ablation antenna, which comprises the following steps:
step 1, assembling a needle head and a tubular part of a non-metal sleeve together;
and 6, coating an outer insulating layer on the outer wall of the outer radiator.
Further, after the step 1 is completed, the outer surface of the needle head is shielded, then the step 2 is executed, and after the step 2 is completed, the shielding of the outer surface of the needle head is removed.
Furthermore, the base is provided with a water inlet and a water outlet, the water inlet is communicated with the inside of the hollow separating cylinder, and the water outlet is communicated with the outer wall of the hollow separating cylinder.
Unlike conventional microwave ablation antennas, the present invention no longer uses a coaxial cable solely to radiate microwave energy, but rather radiates microwave energy outwardly through a hollow prong structure. Compared with the traditional microwave ablation antenna, the microwave ablation antenna has higher radiation efficiency and the ablation form is more approximate to a circle.
Compared with the traditional microwave ablation antenna, under the condition that the size of the non-metal sleeve is the same, the hollow tip structure is adopted, so that the internal cooling water flow is improved, the heat convection area between cooling water and the radiating body is increased, the heat exchange efficiency is enhanced, the surface temperature of the microwave ablation antenna is reduced, and the damage of normal cells caused by overhigh temperature of the microwave ablation antenna is avoided.
Through the technical scheme, compared with the prior art, the invention has the following beneficial effects:
1. the microwave ablation antenna provided by the invention has higher radiation efficiency, and the ablation form is more approximate to a circle;
2. the microwave ablation antenna provided by the invention obtains good cooling efficiency by increasing the convection heat transfer area and improving the flow of the cooling medium, greatly reduces the working temperature at the front end of the microwave ablation antenna and avoids normal tissue cells from being damaged;
drawings
The invention is further illustrated with reference to the following figures and examples.
FIG. 1 is an overall block diagram of a first preferred embodiment of the present invention;
FIG. 2 is an overall block diagram of a second preferred embodiment of the present invention;
fig. 3 is an overall structural view of a conventional microwave ablation antenna;
FIG. 4 is a SAR map of a conventional microwave ablation antenna;
FIG. 5 is a SAR map of the first preferred embodiment provided by the present invention;
FIG. 6 is a SAR map of the second preferred embodiment provided by the present invention;
FIG. 7 is a temperature profile of a conventional microwave ablation antenna;
FIG. 8 is a temperature profile of a first preferred embodiment of the present invention;
FIG. 9 is a temperature profile of a second preferred embodiment of the present invention;
the numbers in the figures are as follows:
in the figure: 1-needle head, 2-nonmetal sleeve, 21-inner radiator, 22-outer radiator, 23-inner insulating layer, 3-outer insulating layer, 4-hollow separating cylinder, 5-water outlet, 6-water inlet, 7-coaxial cable, 71-inner conductor, 72-dielectric layer and 73-outer conductor.
Detailed Description
The present invention will now be described in further detail with reference to the accompanying drawings. In the description of the present application, it is to be understood that the terms "left side", "right side", "upper part", "lower part", and the like, indicate orientations or positional relationships based on the orientations or positional relationships shown in the drawings, and are only for convenience in describing the present invention and simplifying the description, but do not indicate or imply that the referred device or element must have a specific orientation, be constructed in a specific orientation, and be operated, and thus, should not be construed as limiting the present invention. The specific dimensions used in the present example are only for illustrating the technical solution and do not limit the scope of protection of the present invention.
Example one
As shown in fig. 1, the microwave ablation antenna of this embodiment includes a needle 1, a non-metallic sleeve 2, an outer insulating layer 3, a hollow partition 4, a water inlet 6, a water outlet 5, and a coaxial cable 7. The needle head 1 is in a hollow conical shape, is arranged in front of the nonmetal sleeve 2 and is matched with the nonmetal sleeve 2. The non-metal sleeve 2 is composed of a hollow cylindrical tubular part and a base, and the outer surface of the front end of the non-metal sleeve 2 is matched with the inner surface of the rear end of the needle head 1. The inner radiator 21 covers the inner surface of the non-metal sleeve 2 and the needle 1, the outer radiator 22 covers the outer surface of the non-metal sleeve 2, and the inner insulating layer 23 covers the inner surface of the inner radiator 21, so that the cooling water is prevented from directly contacting the inner radiator 21. An outer insulating layer 3 covers the outer radiator 22 and the outer surface of the coaxial cable 7, the front end of which is connected to the rear of the needle 1. The hollow partition cylinder 4 is installed inside the non-metal sleeve 2 for dividing the inflow and outflow of the cooling water. The water inlet 6 is arranged at the lower part of the cavity formed by the hollow separating cylinder 4, and the water outlet 5 is arranged at the lower part of the cavity formed by the non-metal sleeve 2 and the hollow separating cylinder 4. As shown in fig. 1, a gap between the inner insulating layer 23 and the hollow partition 4 serves as a return passage for cooling water and is connected to a water outlet 5 provided in the antenna, and the inside of the hollow partition 4 serves as a water inlet passage for cooling water and is connected to a water inlet 6 provided in the antenna. In this embodiment, the water outlet 5 and the water inlet 6 are fixed on the base at the tail of the non-metal sleeve 2. Cooling water flows in from the water inlet 6 and flows out from the water outlet 5, heat is taken away, and the internal temperature of the antenna is reduced. The coaxial cable 7 is connected to the base of the non-metallic sleeve 2 and comprises an inner conductor 71, a dielectric layer 72 and an outer conductor 73. The inner conductor 71 is electrically connected to the inner radiator 21, the dielectric 72 is used to separate the inner conductor 71 from the outer conductor 73, and the outer conductor 73 is electrically connected to the outer radiator 22. The coaxial cable 7 is electrically connected with the microwave generator and provides energy for the microwave ablation antenna.
In this example, the needle 1 is made of zirconia material. Compared with common stainless steel materials, the zirconia material has high hardness, good electrical insulation, high melting point and good dimensional stability (when the temperature changes, the size hardly changes), and ensures the stability of the radiation performance of the microwave ablation antenna. Both the inner radiator 21 and the outer radiator 22 are made of a conductive metal, copper being the best choice. The cooling water is selected from purified water or deionized water.
The manufacturing method of the microwave ablation antenna comprises the following steps:
step 1, assembling the needle head 1 and the tubular part of the nonmetal sleeve 2 together, and covering and shielding the outer surface of the needle head 1, wherein a high-temperature-resistant film can be selected for covering and shielding.
And 2, coating metal conducting layers on the inner wall of the needle head 1 and the inner and outer walls of the tubular part of the nonmetal sleeve 2, specifically, putting the needle head 1 and the nonmetal sleeve 2 into metal solution to coat the conducting layers, and removing the needle head covering material after coating. The needle 1 and the metal conductive layer on the inner wall of the non-metal sleeve 2 form an inner radiator 21, and the metal conductive layer on the outer wall of the metal sleeve 2 forms an outer radiator 22.
and 4, fixing the base provided with the hollow partition cylinder 4 at the tail end of the tubular part of the non-metal sleeve 2, wherein the inner wall of the base is sequentially provided with an inner radiator 21 and an inner insulating layer 23, and the outer wall of the base is provided with an outer radiator 22. The water inlet 6 and the water outlet 5 are arranged on the base in advance, the water inlet 6 is communicated with the inside of the hollow separating cylinder 4, and the water outlet 5 is communicated with the outer wall of the hollow separating cylinder 4.
And 6, coating an outer insulating layer 3 on the outer wall of the outer radiator 22.
Thus, the manufacturing of the microwave ablation antenna of the embodiment is completed.
Example two
Fig. 2 shows a microwave ablation antenna according to the second embodiment, which has the same main structure as the first embodiment, except for the needle portion. Specifically, the outer surface of the needle 1 is a conical structure, the inner surface is a concave spherical surface, and the front part of the non-metallic sleeve 2 is provided with a convex part embedded into the concave spherical surface. The inner radiator 21 and the inner insulating layer 23 are sequentially arranged on the inner wall of the convex part of the front part of the non-metal sleeve 2.
The corresponding manufacturing method is also changed, and specifically comprises the following steps:
step 1, assembling the needle head 1 and the nonmetal sleeve 2 together, and covering and shielding the outer surface of the needle head 1, wherein a high-temperature-resistant film can be selected for covering and shielding.
And 2, coating the inner wall and the outer wall of the non-metal sleeve 2 with a metal conducting layer, specifically, putting the needle 1 and the non-metal sleeve 2 into a metal solution to coat the conducting layer, and removing the needle covering material after coating. The metal conductive layer on the inner wall of the non-metallic sleeve 2 forms an inner radiator 21 and the metal conductive layer on the outer wall of the metallic sleeve 2 forms an outer radiator 22.
and 4, fixing the base provided with the hollow partition cylinder 4 at the tail end of the non-metal sleeve 2, wherein an inner radiator 21 and an inner insulating layer 23 are sequentially arranged on the inner wall of the base, and an outer radiator 22 is arranged on the outer wall of the base. The water inlet 6 and the water outlet 5 are arranged on the base in advance, the water inlet 6 is communicated with the inside of the hollow separating cylinder 4, and the water outlet 5 is communicated with the outer wall of the hollow separating cylinder 4.
And 6, coating an outer insulating layer 3 on the outer wall of the outer radiator 22.
Thus, the manufacturing of the microwave ablation antenna of the embodiment is completed.
Unlike conventional microwave ablation antennas (as shown in fig. 3, where the reference numbers refer to the above) the present invention does not use coaxial cable solely to radiate microwave energy, but rather radiates microwave energy outwardly through a hollow tip structure. Under the condition that the sizes of the non-metal sleeves are the same, the invention not only improves the internal cooling water flow, but also increases the heat convection area between the cooling water and the radiating body, enhances the heat exchange efficiency, reduces the surface temperature of the microwave ablation antenna and avoids the damage of normal cells caused by overhigh temperature of the microwave ablation antenna.
As shown in fig. 4-6, SAR maps (SAR is the specific absorption rate, reflecting the absorption rate of the surrounding biological tissue for microwave energy) are provided for conventional microwave ablation antennas and preferred embodiments one and two of the present invention provide for operation within biological tissue. In FIGS. 4-6, the microwave source power is 1W, and the SAR value of the biological tissue is 60W/kg as the standard for biological tissue ablation, and the biological tissue is divided into two parts, wherein the SAR value of the light-color area is more than 60W/kg, and the SAR value of the dark-color area is less than 60W/kg. As can be seen from fig. 4-6, the ablation profile of the conventional microwave ablation antenna is elliptical, whereas the preferred embodiment of the first and second ablation profiles provided by the present invention more closely approximates a circle.
Table 1 shows detailed data of a conventional microwave ablation antenna and SAR map of the first and second preferred embodiments of the present invention (the ablation profile is based on 60W/kg).
TABLE 1
As can be seen from table 1, the SAR maximum value of the conventional microwave ablation antenna is higher than that of the first and second preferred embodiments provided by the present invention, and the axial ratio of the microwave ablation antenna of the first and second preferred embodiments provided by the present invention is closer to 1. This is because the conventional microwave ablation antenna has a high SAR maximum value and an unrounded ablation shape because the radiation energy is concentrated in a partial region, which results in an increased absorption amount of the microwave energy by a part of the biological tissue. The microwave ablation antenna designed by the invention has more uniform radiation, and the surrounding biological tissues absorb microwave energy more uniformly, so that the axial ratio (namely the ratio of the transverse length to the longitudinal length of the ablation form) is closer to 1, and the ablation form is closer to a circle.
As shown in fig. 7-9, temperature profiles for a conventional microwave ablation antenna and preferred embodiments one and two of the present invention are provided. In fig. 7-9, the microwave source power is 60W, the working time is 20s, and the temperature value of 60 ℃ is used as the standard for biological tissue ablation, so that the biological tissue is divided into two parts, wherein the temperature value of the light color area is greater than 60 ℃ and the temperature value of the dark color area is less than 60 ℃. As can be seen from fig. 7-9, the ablation profile of the conventional microwave ablation antenna is elliptical, whereas the ablation profiles of the first and second microwave ablation antennas of the preferred embodiment of the present invention more closely approximate a circle.
Table 2 shows detailed data of temperature distribution profiles of the conventional microwave ablation antenna and the microwave ablation antenna designed according to the present invention (the ablation profile is based on 60 ℃).
TABLE 2
Maximum temperature (. degree. C.) | Horizontal length (mm) | Lengthwise (mm) | Axial ratio (horizontal length/longitudinal length) | |
Tradition of | 80.67 | 17.98 | 26.63 | 0.68 |
Example one | 73.79 | 19.86 | 24.30 | 0.82 |
Example two | 74.34 | 20.17 | 22.96 | 0.87 |
As can be seen from Table 2, the maximum temperature value of the conventional microwave ablation antenna is higher than that of the designed microwave ablation antenna, and the axial ratio of the first microwave ablation antenna and the second microwave ablation antenna provided by the preferred embodiment of the invention is higher. The phenomenon is basically consistent with the phenomenon in SAR images (figures 4-7), the microwave ablation antenna designed by the invention has more uniform energy radiation, avoids the problem of overhigh working temperature at the front end of the antenna, effectively protects normal tissues, is more beneficial to accurate control of the operation due to a round ablation form, and has wide market prospect.
It will be understood by those skilled in the art that, unless otherwise defined, all terms (including technical and scientific terms) used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this application belongs. It will be further understood that terms, such as those defined in commonly used dictionaries, should be interpreted as having a meaning that is consistent with their meaning in the context of the prior art and will not be interpreted in an idealized or overly formal sense unless expressly so defined herein.
The meaning of "and/or" as used herein is intended to include both the individual components or both.
The term "connected" as used herein may mean either a direct connection between components or an indirect connection between components via other components.
In light of the foregoing description of the preferred embodiment of the present invention, many modifications and variations will be apparent to those skilled in the art without departing from the spirit and scope of the invention. The technical scope of the present invention is not limited to the content of the specification, and must be determined according to the scope of the claims.
Claims (10)
1. A microwave ablation antenna comprises a needle head (1) and a coaxial cable (7), and is characterized by further comprising: be fixed in non-metallic sleeve (2) at syringe needle (1) rear and locate cavity in non-metallic sleeve (2) and separate a section of thick bamboo (4), syringe needle (1) and non-metallic sleeve (2) inner wall are equipped with inner radiator (21) of being connected with coaxial cable (7) inner conductor (71) electricity, and the outer wall of non-metallic sleeve (2) is equipped with outer radiator (22) of being connected with coaxial cable (7) outer conductor (73) electricity, the inner wall coating of inner radiator (21) has inner insulating layer (23), and inner insulating layer (23) and cavity separate the return water course of a clearance between a section of thick bamboo (4) as the cooling water to with set up in delivery port (5) of antenna and be connected, the cavity separates the inside of a section of thick bamboo (4) as the inlet channel of cooling water, and with set up in water inlet (6) of antenna and be connected.
2. A microwave ablation antenna according to claim 1, wherein: and an outer insulating layer (3) is arranged on the outer wall of the outer radiating body (22).
3. A microwave ablation antenna according to claim 1, wherein: the non-metal sleeve (2) is composed of a tubular part and a base, and the water outlet (5) and the water inlet (6) are fixed on the base.
4. A microwave ablation antenna according to claim 1, wherein: the inner surface and the outer surface of the needle head (1) are both conical structures.
5. A microwave ablation antenna according to claim 1, wherein: the outer surface of the needle head (1) is of a conical structure, the inner surface of the needle head is of an inwards concave spherical surface, and the front part of the non-metal sleeve (2) is provided with a convex part embedded into the inwards concave spherical surface.
6. A microwave ablation antenna according to claim 5, wherein: the inner wall of the convex part at the front part of the non-metal sleeve (2) is sequentially provided with an inner radiator (21) and an inner insulating layer (23).
7. A microwave ablation antenna according to claim 1, wherein: a dielectric layer (72) is arranged between the inner conductor (71) and the outer conductor (73) of the coaxial cable (7).
8. The method of manufacturing the microwave ablation antenna of claim 1, comprising the steps of:
step 1, assembling a needle head (1) and a tubular part of a non-metal sleeve (2) together;
step 2, coating metal conducting layers on the inner wall of the needle head (1) and the inner and outer walls of the tubular part of the non-metal sleeve (2), forming an inner radiating body (21) by the metal conducting layers on the inner walls of the needle head (1) and the non-metal sleeve (2), and forming an outer radiating body (22) by the metal conducting layers on the outer wall of the metal sleeve (2);
step 3, coating an inner insulating layer (23) on the inner surface of the inner radiator (21);
step 4, fixing the base provided with the hollow separation cylinder (4) at the tail end of the tubular part of the non-metal sleeve (2), wherein an inner radiator (21) and an inner insulating layer (23) are sequentially arranged on the inner wall of the base, and an outer radiator (22) is arranged on the outer wall of the base;
step 5, fixing the coaxial cable (7), electrically connecting an inner conductor (71) of the coaxial cable (7) with the inner radiator (21), and electrically connecting an outer conductor (73) of the coaxial cable (7) with the outer radiator (22);
and 6, coating an outer insulating layer (3) on the outer wall of the outer radiator (22).
9. A method of manufacturing a microwave ablation antenna according to claim 8, wherein: after the step 1 is finished, the outer surface of the needle head (1) is shielded, then the step 2 is executed, and after the step 2 is finished, the shielding of the outer surface of the needle head (1) is removed.
10. A method of manufacturing a microwave ablation antenna according to claim 8, wherein: the base is provided with a water inlet (6) and a water outlet (5), the water inlet (6) is communicated with the inside of the hollow separating cylinder (4), and the water outlet (5) is communicated with the outer wall of the hollow separating cylinder (4).
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Citations (8)
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CN213963618U (en) * | 2020-09-16 | 2021-08-17 | 深圳友合然科技有限公司 | Multifunctional microwave ablation needle |
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CN205433888U (en) * | 2016-03-11 | 2016-08-10 | 南阳市第二人民医院 | Novel melt needle |
US20210220048A1 (en) * | 2017-04-20 | 2021-07-22 | Mima-Pro (Nan Tong) Scientific Inc | Circular Microwave Ablation Antenna and System |
CN107865691A (en) * | 2017-11-22 | 2018-04-03 | 安徽硕金医疗设备有限公司 | A kind of water-cooled microwave ablation needle of magnetic resonance compatible |
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CN109953824A (en) * | 2019-04-25 | 2019-07-02 | 南京康友医疗科技有限公司 | A kind of microwave ablation needle body, microwave melt needle and microwave ablation method |
CN110507414A (en) * | 2019-09-16 | 2019-11-29 | 浙江大学 | A kind of more gap microwave melt needles |
CN213963618U (en) * | 2020-09-16 | 2021-08-17 | 深圳友合然科技有限公司 | Multifunctional microwave ablation needle |
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