CN114366212B - Gelatin sponge strip conveying system for temporary arterial embolism - Google Patents
Gelatin sponge strip conveying system for temporary arterial embolism Download PDFInfo
- Publication number
- CN114366212B CN114366212B CN202210065195.2A CN202210065195A CN114366212B CN 114366212 B CN114366212 B CN 114366212B CN 202210065195 A CN202210065195 A CN 202210065195A CN 114366212 B CN114366212 B CN 114366212B
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- China
- Prior art keywords
- gelatin sponge
- main body
- conveyer
- sponge strip
- head end
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- 108010010803 Gelatin Proteins 0.000 title claims abstract description 59
- 229920000159 gelatin Polymers 0.000 title claims abstract description 59
- 239000008273 gelatin Substances 0.000 title claims abstract description 59
- 235000019322 gelatine Nutrition 0.000 title claims abstract description 59
- 235000011852 gelatine desserts Nutrition 0.000 title claims abstract description 59
- 206010014513 Embolism arterial Diseases 0.000 title claims abstract description 9
- 230000006835 compression Effects 0.000 claims description 7
- 238000007906 compression Methods 0.000 claims description 7
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 7
- 239000007787 solid Substances 0.000 claims description 5
- 230000004872 arterial blood pressure Effects 0.000 claims description 4
- 210000004369 blood Anatomy 0.000 claims description 4
- 239000008280 blood Substances 0.000 claims description 4
- 239000003086 colorant Substances 0.000 claims description 4
- 230000010108 arterial embolization Effects 0.000 claims description 2
- 238000000576 coating method Methods 0.000 claims description 2
- 230000000740 bleeding effect Effects 0.000 claims 1
- 208000005189 Embolism Diseases 0.000 abstract description 10
- 210000004204 blood vessel Anatomy 0.000 abstract description 6
- 230000017531 blood circulation Effects 0.000 abstract description 4
- 230000002093 peripheral effect Effects 0.000 abstract description 3
- 238000011282 treatment Methods 0.000 abstract description 3
- 230000003073 embolic effect Effects 0.000 description 5
- 239000000463 material Substances 0.000 description 5
- 239000011247 coating layer Substances 0.000 description 4
- 230000000694 effects Effects 0.000 description 3
- 238000002347 injection Methods 0.000 description 3
- 239000007924 injection Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 230000010102 embolization Effects 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 230000002792 vascular Effects 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 206010017076 Fracture Diseases 0.000 description 1
- 206010021338 Iliac artery embolism Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 206010034246 Pelvic fractures Diseases 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 208000018525 Postpartum Hemorrhage Diseases 0.000 description 1
- 206010063544 Renal embolism Diseases 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000002872 contrast media Substances 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000007865 diluting Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000013161 embolization procedure Methods 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 208000031169 hemorrhagic disease Diseases 0.000 description 1
- 210000002767 hepatic artery Anatomy 0.000 description 1
- 230000036512 infertility Effects 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 231100000956 nontoxicity Toxicity 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 238000002601 radiography Methods 0.000 description 1
- 210000002254 renal artery Anatomy 0.000 description 1
- 210000000952 spleen Anatomy 0.000 description 1
- 230000009278 visceral effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12099—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder
- A61B17/12109—Occluding by internal devices, e.g. balloons or releasable wires characterised by the location of the occluder in a blood vessel
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B17/12131—Occluding by internal devices, e.g. balloons or releasable wires characterised by the type of occluding device
- A61B17/12159—Solid plugs; being solid before insertion
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B17/12—Surgical instruments, devices or methods, e.g. tourniquets for ligaturing or otherwise compressing tubular parts of the body, e.g. blood vessels, umbilical cord
- A61B17/12022—Occluding by internal devices, e.g. balloons or releasable wires
- A61B2017/1205—Introduction devices
Landscapes
- Health & Medical Sciences (AREA)
- Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Reproductive Health (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention relates to a gelatin sponge strip conveying system for temporary arterial embolism, which comprises a conveyer and gelatin sponge strips preset in the conveyer, wherein the conveyer comprises a tubular conveyer main body, the gelatin sponge strips are preset in the conveyer main body, one end of the conveyer main body is provided with a head end fixing ring, the other end of the conveyer main body is provided with a tail end base, the head end of the conveyer main body is connected with a corresponding intervention catheter through the head end fixing ring, the tail end of the conveyer main body is connected with a corresponding injector through the tail end base, and the injector is convenient for pushing and conveying the gelatin sponge strips in the conveyer main body to a target vessel to be occluded through the intervention catheter. The invention can prefabricate the gelatin sponge strip in the conveying system, can directly connect the intervention catheter and the injector when in use, rapidly complete embolism, has short time consumption and good stability, meets the sterile requirement, can be widely applied to central type embolism of peripheral thicker blood vessels, blood flow diversion and other intervention treatments, and has very broad prospect.
Description
Technical Field
The invention relates to the technical field of medical appliances, in particular to a gelatin sponge strip conveying system for temporary arterial embolism.
Background
Vascular embolization is an important technique for interventional medicine, and its clinical application is very wide. For example, internal iliac artery embolism for treating pelvic fracture, postpartum hemorrhage, internal maxillo artery embolism for treating craniofacial fracture, hepatic artery, spleen artery, renal artery embolism for treating visceral rupture, etc.
The selection of suitable embolic materials is the basis for ensuring the success of the embolization procedure. At present, embolic materials are various, and solid spring rings, gelatin sponge, polyethylene particles, liquid absolute ethyl alcohol, medical glue and the like are included. Among them, gelatin sponge is the most commonly used solid temporary embolic material, which is widely used for treating tumor and hemorrhagic disease due to its low cost, non-toxicity and good biocompatibility, and the gelatin sponge in the body is degraded for about 14 days, and the blood vessel is recanalized, which is the property that permanent embolic materials such as spring coil do not have.
However, currently available gelatin sponge embolic products are only gelatin sponge particles, which vary in diameter from 150 μm to 2000 μm, and do not fully meet clinical needs. For coarser vessels, temporary diversion of blood flow, simple central embolization, etc., a larger volume of gelatin sponge embolizing material is needed, which is easy to deliver.
Clinically, doctors adopt self-made gelatin sponge strips to cope with the above conditions. However, the intraoperative self-made procedure is long, unstable (in volume), and prone to violations of sterility requirements. More importantly, no effective delivery system exists, and the gelatin sponge swells when meeting water, so that the tube is easily blocked or the embolism is easily failed by directly pushing with a syringe.
Aiming at the problems, the invention provides a gelatin sponge strip conveying system for temporary arterial embolism, which can meet the requirements, and can be widely applied to central embolism of peripheral coarser blood vessels, blood flow diversion and other interventional treatments, and has very broad prospects.
Disclosure of Invention
The present invention aims to overcome the problems of the prior art and to provide a gelatin sponge strip delivery system for temporary arterial embolization.
In order to achieve the technical purpose and the technical effect, the invention is realized by the following technical scheme:
a gelatin sponge strip conveying system for temporary arterial embolism comprises a conveyer and gelatin sponge strips preset in the conveyer, wherein the conveyer comprises a tubular conveyer main body, the gelatin sponge strips are preset in the conveyer main body, one end of the conveyer main body is provided with a head end fixing ring, the other end of the conveyer main body is provided with a tail end base, the head end of the conveyer main body is connected with a corresponding intervention catheter through the head end fixing ring, the tail end of the conveyer main body is connected with a corresponding injector through the tail end base, and the gelatin sponge strips in the conveyer main body are conveniently injected and conveyed to a target vessel to be embolized through the intervention catheter.
Further, be equipped with the head end safety plug in the head end of conveyer main part for the one end of fixed gelatin sponge strip, and form the headspace when extracting and hold the blood/water that overflows from intervention pipe, be equipped with the tail end safety plug in the tail end of conveyer main part, be used for the other end of fixed gelatin sponge strip, and seal the tail end of conveyer main part, make the conveyer main part keep certain interior pressure when connecting intervention pipe, prevent to intervene the pipe and overflow and bleed/water along with arterial pressure.
Further, the outer side end of the head end safety plug is provided with a spherical cap, so that the head end safety plug can be pulled out conveniently.
Further, the spherical cap of the head end safety plug is provided with different colors, lines, letters or numbers to represent different compression multiples.
Further, the outer side end of the tail end safety plug is provided with a circular ring, so that the tail end safety plug can be pulled out conveniently.
Furthermore, the tail end base is provided with coatings or numbers with different numbers to represent the length of the gelatin sponge strip matched with the corresponding gelatin sponge strip.
Further, the inner surface of the head end fixing ring is provided with an internal thread, one end of the intervention catheter is provided with a catheter joint, the catheter joint is provided with an external thread matched with the internal thread of the head end fixing ring, and the intervention catheter is connected with the head end fixing ring through the catheter joint thread.
The beneficial effects of the invention are as follows:
the invention can prefabricate the gelatin sponge strip in the conveying system, can directly connect the intervention catheter and the injector when in use, rapidly complete embolism, has short time consumption and good stability, meets the sterile requirement, can be widely applied to central type embolism of peripheral thicker blood vessels, blood flow diversion and other intervention treatments, and has very broad prospect.
Drawings
FIG. 1 is a schematic diagram of a conveying system according to the present invention;
FIG. 2 is a schematic illustration of the connection of the delivery system of the present invention to a syringe and an interventional catheter, respectively;
fig. 3 is a schematic view of the interventional catheter of the present invention.
The reference numerals in the figures illustrate: 1. the conveyer comprises a conveyer main body, 2, a head end fixing spiral ring, 3, a tail end base, 4, a gelatin sponge strip, 5, a head end safety plug, 51, a spherical cap, 6, a tail end safety plug, 61, a circular ring, 7, a syringe, 8, an intervention catheter, 81 and a catheter connector.
Detailed Description
The invention will be described in detail below with reference to the drawings in combination with embodiments.
As shown in fig. 1, a gelatin sponge strip conveying system for temporary arterial embolism, the system includes a conveyor and gelatin sponge strips 4 preset in the conveyor, in this embodiment, the gelatin sponge strips 4 can be processed by gelatin sponge on the market, the diameter of the gelatin sponge strips 4 is unified to be 0.9mm, so that the gelatin sponge strips 4 can pass through common 4F or 5F catheters, the length of the gelatin sponge strips is 10mm and 15mm for clinical selection (the too short effect is not obvious, the conveying is difficult if the too short effect is too long), the compression multiple is 1 times, 1.5 times and 2 times, the compression multiple is 1 times, 1 time refers to cutting gelatin sponge into raw strips with the diameter of 1.8mm, and compressing the raw strips to finished strips with the diameter of 0.9mm, and the rest is analogized, the conveyor comprises a tubular conveyor main body 1, in this embodiment, the conveyor main body 1 adopts a metal tube with the inner diameter of 0.9mm, the length of 30mm, the gelatin sponge strips 4 are preset in the conveyor main body 1, the space between the gelatin sponge strips 4 and the end 5mm of the conveyor main body 1 is provided with a fixing ring 3, and the end of the conveyor main body 1 is provided with a corresponding injection ring 2, and the end of the end main body 2 is provided with a fixing ring 2 is provided with a corresponding injection seat 2, and the end of the end main body 1 is connected with the end 1 main body 1 is provided with a corresponding injection needle 1 through the injector 1.
The head end safety plug 5 is arranged in the head end of the conveyor main body 1, the length of the head end safety plug 5 is 5mm and is used for fixing one end of the gelatin sponge strip 4, falling is prevented, a reserved space is formed to contain blood/water overflowed from the intervention catheter 8 when the gelatin sponge strip is pulled out, the tail end safety plug 6 is arranged in the tail end of the conveyor main body 1, the length of the tail end safety plug 6 is 20mm and 15mm, the two types of gelatin sponge strips 4 with the lengths of 10mm and 15mm are respectively corresponding to the other end of the gelatin sponge strip 4 and are used for fixing the other end of the gelatin sponge strip 4, falling is prevented, the tail end of the conveyor main body 1 is sealed, certain internal pressure is kept when the conveyor main body 1 is connected with the intervention catheter 8, and the intervention catheter 8 is prevented from overflowing with arterial pressure.
The outer side end of the head end safety plug 5 is provided with a spherical cap 51, so that the head end safety plug 5 can be pulled out conveniently.
The spherical cap 51 of the head-end safety plug 5 is provided with three colors of yellow, blue and red, wherein yellow represents 1-time compression multiple, blue represents 1.5-time compression multiple and red represents 2-time compression multiple, respectively, and different colors, lines, letters or numbers are arranged on the spherical cap 51 of the head-end safety plug 5.
The outer side end of the tail end safety plug 6 is provided with a circular ring 61, so that the tail end safety plug 6 can be conveniently pulled out.
The tail end base 3 is provided with the coating layers or the numbers with different numbers to represent the lengths of the corresponding gelatin sponge strips 4, in the embodiment, the coating layers are adopted to represent that the length of the 1 coating layer representing the gelatin sponge strip 4 is 10mm, the length of the 2 coating layers representing the gelatin sponge strip 4 is 15mm, the specification of the gelatin sponge strip 4 is more intuitively identified, and the misuse during operation is prevented.
The inner surface of the head end fixing ring 2 is provided with internal threads, as shown in fig. 3, one end of the intervention catheter 8 is provided with a catheter connector 81, the catheter connector 81 is provided with external threads matched with the internal threads of the head end fixing ring 2, and the intervention catheter 8 is in threaded connection with the head end fixing ring 2 through the catheter connector 81.
The application method and principle of the invention
In the interventional embolism operation, after the interventional catheter 8 reaches a target blood vessel, the tail section of the interventional catheter 8 is lifted and plugged, so that water or blood is prevented from overflowing along with arterial pressure; the assistant unpacks the package of the conveying system, pulls out the head end safety plug 5 of the conveyer, delivers the safety plug to an operator, and the operator connects the head end fixing ring 2 of the conveyer to the catheter joint 81 at the tail section of the interventional catheter 8, and rotates and fastens the safety plug, thereby tightly fixing the interventional catheter 8 and the conveyer to be connected into a whole; the operator pulls out the tail end safety plug 6 of the conveyor, connects the injector 7 filled with the diluting contrast agent on the tail end base 3 of the conveyor, rapidly and softly pushes and injects, and conveys the gelatin sponge strip 4 to the target blood vessel to be embolized; the catheter adapter 81 and the head end fixing ring 2 are unscrewed, the conveyor is taken down, the interventional catheter 8 is used for radiography, the condition of the target vascular embolism is known, and whether the embolism is continued or not is determined until satisfaction.
The above description is only of the preferred embodiments of the present invention and is not intended to limit the present invention, but various modifications and variations can be made to the present invention by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (3)
1. A gelatin sponge strip conveying system for temporary arterial embolism, characterized in that the system comprises a conveyer and a gelatin sponge strip (4) preset in the conveyer, the conveyer comprises a tubular conveyer main body (1), the gelatin sponge strip (4) is preset in the conveyer main body (1), one end of the conveyer main body (1) is provided with a head end fixing ring (2), the other end is provided with a tail end base (3), the head end of the conveyer main body (1) is connected with a corresponding intervention catheter (8) through the head end fixing ring (2), the tail end of the conveyer main body (1) is connected with a corresponding injector (7) through the tail end base (3), the injector (7) is convenient for pushing the gelatin sponge strip (4) in the conveyer main body (1) to a target vessel to be occluded through the intervention catheter (8), a head end safety plug (5) is arranged in the head end of the conveyer main body (1) and used for fixing one end of the gelatin sponge strip (4), a reserved space is formed for accommodating blood/water overflowed from the intervention catheter (8) during pulling out, the tail end of the conveyer main body (1) is provided with the tail end base (3) to be connected with the corresponding injector (7) so that the injector (7) can push the gelatin sponge strip (4) in the conveyer main body (1) to be plugged, the target vessel is sealed, the inner pressure of the gelatin sponge strip is sealed and the inner pressure of the target vessel is kept, and the inner pressure of the gelatin sponge strip is sealed, prevent to intervene pipe (8) follow-up arterial pressure excessive bleeding/water, the outside end of head end safety plug (5) is equipped with spherical cap (51), is convenient for extract head end safety plug (5), the outside end of tail end safety plug (6) is equipped with ring (61), is convenient for extract tail end safety plug (6), the internal surface of head end solid fixed ring (2) is equipped with the internal thread, the one end of intervene pipe (8) is equipped with pipe joint (81), be equipped with on pipe joint (81) with head end solid fixed ring (2) internal thread matched with external screw thread, intervene pipe (8) pass through pipe joint (81) threaded connection head end solid fixed ring (2).
2. Gelatin sponge strip delivery system for temporary arterial embolism as claimed in claim 1 wherein the spherical cap (51) of the head end safety plug (5) is provided with different colours, textures, letters or numbers to indicate different compression factors.
3. Gelatin sponge strip delivery system for temporary arterial embolization according to claim 1, wherein the tail base (3) is provided with different numbers of coatings or numbers to indicate matching of the corresponding gelatin sponge strip (4) length.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210065195.2A CN114366212B (en) | 2022-01-20 | 2022-01-20 | Gelatin sponge strip conveying system for temporary arterial embolism |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202210065195.2A CN114366212B (en) | 2022-01-20 | 2022-01-20 | Gelatin sponge strip conveying system for temporary arterial embolism |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114366212A CN114366212A (en) | 2022-04-19 |
| CN114366212B true CN114366212B (en) | 2024-03-12 |
Family
ID=81145016
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN202210065195.2A Active CN114366212B (en) | 2022-01-20 | 2022-01-20 | Gelatin sponge strip conveying system for temporary arterial embolism |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN114366212B (en) |
Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6511468B1 (en) * | 1997-10-17 | 2003-01-28 | Micro Therapeutics, Inc. | Device and method for controlling injection of liquid embolic composition |
| CN202086886U (en) * | 2011-03-06 | 2011-12-28 | 杭州艾力康医药科技有限公司 | Injectable solid embolic agent |
| CN104288843A (en) * | 2014-10-31 | 2015-01-21 | 上海世正医疗科技股份有限公司 | Spleen and kidney embolic material as well as preparation method and using method thereof |
| CN107320246A (en) * | 2017-08-08 | 2017-11-07 | 滕皋军 | A kind of hemostasis gelfoam and its implanting device |
| CN110876812A (en) * | 2019-12-06 | 2020-03-13 | 赛克赛斯生物科技股份有限公司 | Gelatin sponge suppository, preparation method and application thereof, and medicine for treating vascular diseases or tumors |
| CN111134756A (en) * | 2019-12-30 | 2020-05-12 | 西安交通大学 | Fibrous chronic embolism device for preventing ectopic embolism |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6610026B2 (en) * | 1998-05-01 | 2003-08-26 | Sub-Q, Inc. | Method of hydrating a sponge material for delivery to a body |
| US20070038244A1 (en) * | 2001-06-08 | 2007-02-15 | Morris Edward J | Method and apparatus for sealing access |
-
2022
- 2022-01-20 CN CN202210065195.2A patent/CN114366212B/en active Active
Patent Citations (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6511468B1 (en) * | 1997-10-17 | 2003-01-28 | Micro Therapeutics, Inc. | Device and method for controlling injection of liquid embolic composition |
| CN202086886U (en) * | 2011-03-06 | 2011-12-28 | 杭州艾力康医药科技有限公司 | Injectable solid embolic agent |
| CN104288843A (en) * | 2014-10-31 | 2015-01-21 | 上海世正医疗科技股份有限公司 | Spleen and kidney embolic material as well as preparation method and using method thereof |
| CN107320246A (en) * | 2017-08-08 | 2017-11-07 | 滕皋军 | A kind of hemostasis gelfoam and its implanting device |
| CN110876812A (en) * | 2019-12-06 | 2020-03-13 | 赛克赛斯生物科技股份有限公司 | Gelatin sponge suppository, preparation method and application thereof, and medicine for treating vascular diseases or tumors |
| CN111134756A (en) * | 2019-12-30 | 2020-05-12 | 西安交通大学 | Fibrous chronic embolism device for preventing ectopic embolism |
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| Publication number | Publication date |
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| CN114366212A (en) | 2022-04-19 |
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