CN114344595B - Hemodialysis system continuous dialysis external circulation pipeline capable of switching concentrated solution - Google Patents
Hemodialysis system continuous dialysis external circulation pipeline capable of switching concentrated solution Download PDFInfo
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Abstract
Hemodialysis of changeable concentrateA system continuous dialysis extracorporeal circulation circuit comprising: a blood circulation system, a dialysate system, a waste liquid system and a fluid replacement system; the dialysate system includes a concentrate container, a concentrate line, and a hemodialysis machine. Concentrate container A liquid concentrate bag A 1 And a standby A liquid concentrate bag A 2 And B liquid concentrate bag B 1 And a standby B liquid concentrate bag B 2 The method comprises the steps of carrying out a first treatment on the surface of the A liquid concentrate bag A 1 And a standby A liquid concentrate bag A 2 And B liquid concentrate bag B 1 And a standby B liquid concentrate bag B 2 Different pipelines are used for communicating with the hemodialysis machine under the combination of the circuit breakers. The two hemodialysis devices are connected into the hemodialysis system by adopting different pipeline and circuit breaker combinations. Solves the problems of continuous dialysis in a non-stop state, A, B concentrate waste and emergency rescue of emergency patients with whole body organ failure.
Description
Technical Field
The invention relates to a hemodialysis pipeline, in particular to a continuous dialysis extracorporeal circulation pipeline of a hemodialysis system with a switchable concentrated solution.
Background
In recent years, the incidence of end-stage renal disease (end-stage kidney disease, ESRD) has risen year by year, with a higher rate of population growth. Renal replacement therapy is a treatment modality for end stage renal disease and includes three modalities of renal transplantation, peritoneal dialysis and hemodialysis, with more than 80% of patients being selected to receive hemodialysis treatment. For the general population, the weekly intake of water is about 10-12L. For hemodialysis patients, dialysis is performed 3 times per week for 4 hours, with a dialysis fluid flow rate of 500ml/min, and the weekly exposure to water is about 360L, 30 times that of the normal population. The quality of the dialysate is an important link of hemodialysis quality, and the dialysate contaminated by microorganisms can cause inflammatory reactions of the body. The incidence of micro-inflammatory conditions in dialysis patients is as high as 60-70%, which can induce erythropoiesis resistance in patients, exacerbating the incidence of malnutrition and cardiovascular events.
The dialysate is prepared by mixing A, B concentrate and dialysis water according to a certain proportion by a hemodialysis machine, and is shown in figure 1. The quality control of the dialysate is realized, and three links of water treatment, concentrate preparation and hemodialysis machine maintenance are required to be grasped. The water treatment is used as a first link, the quality of all the following links is directly affected, dialysis water is automatically generated by a reverse osmosis device, and the quality is monitored by engineers; the hemodialysis machine maintenance is used as the most important link of the dialysate entering the dialyzer and exchanging substances with blood, depends on the fact that medical staff strictly select a correct disinfection mode and the periodic maintenance of engineers according to SOP requirements every class, and quality deviation rarely occurs. The current domestic and foreign methods for preparing the concentrated solution are different, and researches show that the pH of the solution A is 3.0, is acidic, is unfavorable for bacterial growth, the pH of the solution B is 8.0, is slightly alkaline, and is suitable for bacterial growth. The quality control of concentrate preparation and supply is important.
Currently, the concentrate preparation and supply modes include a center supply mode and a stand-alone supply mode. The central liquid supply mode is divided into two methods, one is a central concentrate supply system (central dialysis concentrate supply system, CCDS) applied in most countries, as shown in fig. 2; another is the central dialysate supply system (central dialysis fluid delivery system, CDDS) for japanese applications, as shown in fig. 3. CDDS respectively needs three pipelines of A concentrated solution, B concentrated solution and reverse osmosis water to be respectively input into a dialysis machine, and then the dialysis machine prepares into dialysate. The CDDS is one more dialysis fluid supply device than the CCDS, wherein A, B concentrated solution and reverse osmosis water are mixed into dialysis fluid in the device, and then the dialysis fluid is conveyed to a dialysis machine through a single infusion pipeline for direct use. The CDDS centralized liquid supply equipment has high automation degree, reduces the length of a tail end disinfection pipeline, is safe and efficient, and uses a CDDS system in 90% of dialysis centers in Japan. The disadvantage of this system is that the directly supplied dialysis fluid requires the use of dialysis machines of the same brand, is not compatible with other brands, and limits its popularization. In korea, CCDS systems are used for centralized liquid supply. In Europe, the A concentrate adopts a central liquid supply mode, and the B concentrate adopts an online dissolution supply mode of a bicarbonate dry powder barrel. Part of the country considers the need for personalized dialysis treatment of patients and can even provide 2 formulas of A concentrate from A 1 ，A 2 The double concentrate pipe carries the liquid. In China, central liquid supply is just started, and is not fully popularized, and more dialysis centers select a single machine supply mode. In a single-machine supply mode, which can be divided againThe following five types are adopted: (1) purchasing A, B dry powder, and preparing A, B concentrated solution according to manufacturer's instructions; (2) purchasing the finished product of the concentrated solution A and the dry powder B to prepare the concentrated solution B according to the manufacturer's instructions; (3) purchasing A, B concentrate of the finished product, and directly using; (4) purchasing the finished product of the concentrated solution A, and preparing the concentrated solution B on line by a dialysis machine through a dry powder cylinder B; (5) the powder cartridge of A, B is purchased and A, B concentrate is prepared on line by a dialysis machine. Because A, B dry powder cylinders are expensive, most dialysis centers select the first three modes of fluid supply in view of the national conditions of China.
By adopting the first dialysis fluid supply mode, the repeated use, cleaning and disinfection of the liquid A and liquid B separation barrels increases the potential pollution risks of disinfectant residues, incomplete disinfection and the like. The second dialysis liquid supply mode is adopted, and the repeated use, cleaning and disinfection of the B liquid separation barrel increases the potential pollution risks of disinfectant residue, incomplete disinfection and the like. With the third dialysate supply mode, using the finished A, B concentrate, while reducing the effort and risk of infection in the formulation link, the following drawbacks still exist:
(1) The storage space is large, and daily delivery, receiving and checking are required. On average, 140 patients were dialyzed daily at the applicant unit blood purification center, and a 10L double serving A, B concentrate was purchased, requiring 140 barrels per day, and requiring a dedicated warehouse to store these liquids.
(2) The dialysate barrel cover and the dialysis machine A, B liquid suction device cannot be sealed, and in the use process, dust and microorganisms can fall into the barrel through the exposed part of the barrel opening to pollute the concentrated liquid.
(3) Waste liquid and increase cost. The dialysis time of each person is 4 hours, and the pre-filling waiting before each treatment and the blood returning and downloading after the treatment are added, so that the actual use time of the dialysis fluid is about 4.5 hours. Calculated as dialysate flow rate 500mL/min, a total of 135L of dialysate was required per person dialysis. The ratio of the dialysis solutions prepared by dialysis machines of different brands is different, and the ratio of the machine A solution to the machine B solution is Fei Senyou S, namely, the ratio of water=1:1.225:32.775, the consumption of each part of concentrated solution A is 3.86L, the consumption of two parts is 7.72L, and the consumption of the other parts is 2.28L; the amount of B concentrate used was 4.73/L per person, 9.46L for two persons and 0.54L for the rest. According to the dialysis fluid use standard, the unused concentrated solution is not allowed to be poured and used together, and the concentrated solution needs to be discarded, so that the daily A, B concentrated solution is wasted surprisingly. If the patient suffers from the change of the illness state, the treatment needs to be finished in advance, and more waste is caused.
(4) The weight of each barrel of the barreled solution A or B of the dialysis solution is 10L, the physical strength bearing range of a nurse is exceeded, and the current working mode is that a health staff places the barreled solution A and B of the concentration solution on a machine base, and the dialysis machine is connected after checking by the nurse. If the hygienist is misplaced, nurses cannot find the hygienist in time, the electric conductivity is unstable and the treatment program cannot be entered; if the change is forgotten between two shifts of the hygienist, the nurse does not find in time, the dialysate is sucked and alarmed, and then the venous pressure and the transmembrane pressure are changed to repeatedly alarm, so that the patient generates tension emotion.
(5) Hemodialysis technique relies on smooth circulation line, and when anticoagulant injection volume is not enough, patient's blood coagulation function is unusual, low blood pressure low flow causes the dialyzer blood to flow slowly, or the vein does not keep effective position or fix inappropriately and cause the vein needle to deviate from after the hemodialysis passageway is established, and the rethread is unsmooth, and blood is isolated, and the pump stop time is too long, and blood coagulation, or arterial needle deviate from the blood vessel and do not have the flow, all can lead to the dialyzer to block, once the dialyzer blocks up, hemodialysis treatment will not continue, causes this hemodialysis treatment to break off, leads to dialysate A liquid and B liquid to scrap.
(6) Hemodialysis cannot be continuously performed, and emergency rescue of patients suffering from whole body organ failure cannot be dealt with. Every time a hemodialysis patient is replaced, the hemodialysis machine, the barreled concentrated solution A and the barreled concentrated solution B are required to be stopped, and the preparation time is long.
Disclosure of Invention
In order to solve the above technical problems, the present invention provides a hemodialysis system continuous dialysis extracorporeal circulation line capable of switching concentrated solution, comprising:
the blood circulation system consists of a blood inlet pipeline, a blood pump, a hemodialysis device and a blood return pipeline;
the dialysate system consists of a concentrate container, a concentrate pipeline, a reverse osmosis water system, a reverse osmosis water pipeline, a hemodialysis machine, a dialysate liquid inlet pump and a dialysate liquid inlet pipeline;
the waste liquid system consists of a liquid discharge pipeline, a liquid discharge pump and a waste liquid container;
and a fluid infusion system comprising a fluid infusion line, a fluid infusion pump, and a fluid infusion container; the hemodialysis device comprises a blood inlet, a blood outlet, a dialysate inlet and a drain outlet;
one end of the blood inlet pipeline is led into an artery of a patient, and the other end of the blood inlet pipeline is connected into a blood inlet of a hemodialysis device after passing through a blood pump;
one end of the blood return pipeline is connected with a blood outlet of the hemodialysis device, and the other end of the blood return pipeline is connected with a vein of a patient; arterial blood of the patient flows into the hemodialysis device through the blood inlet path, is purified by the hemodialysis device, and flows back to the vein of the patient through the blood return path;
one end of the concentrated solution pipeline is connected with the concentrated solution container, and the other end of the concentrated solution pipeline is connected with the hemodialysis machine; one end of the reverse osmosis water pipeline is connected with a reverse osmosis water system, and the other end of the reverse osmosis water pipeline is connected with a hemodialysis machine; the dialysate inlet pipeline is connected with a dialysate inlet; the concentrated solution is filled in the concentrated solution container, the reverse osmosis water system generates reverse osmosis water, the concentrated solution and the reverse osmosis water are prepared into dialysate by the hemodialysis machine according to a proportion, the dialysate flows into the hemodialysis machine through a dialysate inlet pump and a dialysate inlet pipeline, and is subjected to substance exchange with blood flowing through the hemodialysis machine through dispersion, ultrafiltration, adsorption and convection, so that metabolic wastes in the blood are removed, and the balance of blood electrolyte and acid-base is maintained; one end of the liquid discharge pipeline is connected to a liquid discharge outlet of the hemodialysis device, and the other end of the liquid discharge pipeline is connected to a waste liquid container after passing through a liquid discharge pump; one end of the fluid infusion pipeline is connected with the fluid infusion container, and the other end of the fluid infusion pipeline is connected with the blood return pipeline after passing through the fluid infusion pump.
The concentrated solution container comprises a concentrated solution container A and a concentrated solution container B; the A liquid concentrated solution container is a solution bag, and comprises an A liquid concentrated solution bag A 1 And a standby A liquid concentrate bag A 2 The B liquid concentrate container is a solution bag and comprises a B liquid concentrate bag B 1 And a standby B liquid concentrate bag B 2 ；
The concentrated solution pipeline comprises a concentrated solution pipeline A and a concentrated solution pipeline B;
the A concentrated solution pipeline comprises an A concentrated solution pipeline main pipe, an A concentrated solution pipeline first branch and an A concentrated solution pipeline second branch;
the circuit breaker also comprises a first circuit breaker and a second circuit breaker;
one end of the first branch of the A liquid concentrate pipeline is connected with an A liquid concentrate bag A 1 The other end of the main pipe is connected with the main pipe of the A liquid concentrate pipeline after passing through the first circuit breaker;
one end of a second branch of the liquid A concentrated solution pipeline is connected with a standby liquid A concentrated solution bag A2, and the other end of the second branch is connected with a main pipe of the liquid A concentrated solution pipeline after passing through a second circuit breaker;
the main pipe of the liquid A concentrated liquid pipeline is connected to a hemodialysis machine;
the B concentrated solution pipeline comprises a B concentrated solution pipeline main pipe, a B concentrated solution pipeline first branch and a B concentrated solution pipeline second branch;
the circuit further comprises a third circuit breaker and a fourth circuit breaker;
one end of the first branch of the B liquid concentrate pipeline is connected with a B liquid concentrate bag B 1 The other end is connected into a main pipe of the liquid B concentrate pipeline after passing through a third circuit breaker;
one end of the second branch of the B liquid concentrate pipeline is connected with a standby B liquid concentrate bag B 2 The other end is connected into a main pipe of the liquid B concentrate pipeline after passing through a fourth circuit breaker;
b, connecting a main pipe of the liquid concentrate pipeline into a hemodialysis machine;
the number of the hemodialysis devices is two, namely a first hemodialysis device and a second hemodialysis device;
the dialysate inlet pipeline comprises a dialysate inlet pipeline main pipe, a dialysate inlet pipeline first branch pipe and a dialysate inlet pipeline second branch pipe, the dialysate inlet pipeline main pipe is respectively connected and communicated with the dialysate inlet pipeline first branch pipe and the dialysate inlet pipeline second branch pipe, one end of the dialysate inlet pipeline main pipe is connected with the hemodialysis machine, the dialysate inlet pipeline first branch pipe is connected with a dialysate inlet of the first hemodialysis machine after passing through a fifth circuit breaker, and the dialysate inlet pipeline second branch pipe is connected with a dialysate inlet of the second hemodialysis machine after passing through a sixth circuit breaker;
the blood inlet pipeline comprises a blood inlet pipeline main pipe, a blood inlet pipeline first branch pipe and a blood inlet pipeline second branch pipe, the blood inlet pipeline main pipe is respectively connected and communicated with the blood inlet pipeline first branch pipe and the blood inlet pipeline second branch pipe, the blood inlet pipeline main pipe is connected to an artery of a patient after passing through a blood pump, the blood inlet pipeline first branch pipe is connected to a blood inlet of a first hemodialysis device after passing through a seventh circuit breaker, and the blood inlet pipeline second branch pipe is connected to a blood inlet of a second hemodialysis device after passing through an eighth circuit breaker;
the blood return pipeline comprises a blood return pipeline main pipe, a first branch pipe of the blood return pipeline and a second branch pipe of the blood return pipeline, wherein the blood return pipeline main pipe is respectively connected and communicated with the first branch pipe of the blood return pipeline and the second branch pipe of the blood return pipeline, and the blood return pipeline main pipe is connected into a vein of a patient; one end of the first branch pipe of the blood circuit is connected to the blood outlet of the first hemodialysis device, and the other end of the first branch pipe of the blood circuit is connected to the main pipe of the blood circuit after passing through the ninth circuit breaker; one end of the second branch pipe of the blood circuit is connected with the blood outlet of the second hemodialysis device, and the other end of the second branch pipe of the blood circuit is connected with the main pipe of the blood circuit after the tenth circuit breaker;
the liquid discharge pipeline comprises a liquid discharge pipeline main pipe, a liquid discharge pipeline first branch pipe and a liquid discharge pipeline second branch pipe, and the liquid discharge pipeline main pipe is respectively connected and communicated with the liquid discharge pipeline first branch pipe and the liquid discharge pipeline second branch pipe; one end of the first branch pipe of the liquid discharge pipeline is connected to a liquid discharge outlet of the first hemodialysis device, and the other end of the first branch pipe of the liquid discharge pipeline is connected to a main pipe of the liquid discharge pipeline after passing through an eleventh circuit breaker; one end of the second branch pipe of the liquid discharge pipeline is connected to the liquid discharge outlet of the second hemodialysis device, the other end of the second branch pipe of the liquid discharge pipeline is connected to the main pipe of the liquid discharge pipeline after passing through the twelfth circuit breaker, and the main pipe of the liquid discharge pipeline is connected to the waste liquid container after passing through the liquid discharge pump.
Further, a first venous drip cup is arranged on the main pipe of the liquid A concentrated solution pipeline, and a second venous drip cup is arranged on the main pipe of the liquid B concentrated solution pipeline.
Further, an air alarm is arranged on the first branch of the A liquid concentrate pipeline, the second branch of the A liquid concentrate pipeline, the first branch of the B liquid concentrate pipeline and the second branch of the B liquid concentrate pipeline respectively, and the air alarm is electrically connected with the hemodialysis machine.
Further, the A liquid concentrate bag A 1 And a standby A liquid concentrate bag A 2 The volumes of the liquid B and the concentrated liquid bag B are all 2-15L 1 And a standby B liquid concentrate bag B 2 The volumes of (2) and (15) L.
Further, the A liquid concentrate bag A 1 And a standby A liquid concentrate bag A 2 The volumes of the liquid B and the concentrated liquid bag B are all 5L 1 And a standby B liquid concentrate bag B 2 Is 5L.
Further, the device also comprises a second blood inlet pipeline and a second blood return pipeline; the second blood circuit is connected to the blood inlet of the second hemodialysis device after passing through the blood pump and the thirteenth circuit breaker respectively; the second blood circuit is connected to the blood outlet of the second hemodialysis device after passing through the fourteenth circuit breaker;
the fluid infusion pipeline comprises a fluid infusion pipeline main pipe, a fluid infusion pipeline first branch pipe and a fluid infusion pipeline second branch pipe, one end of the fluid infusion pipeline main pipe is connected to the fluid infusion container after passing through the fluid infusion pump, the fluid infusion pipeline first branch pipe is connected to the return vessel circuit, and the fluid infusion pipeline second branch pipe is connected to the second return vessel circuit after passing through the fifteenth circuit breaker.
Further, A liquid concentrate bag A 1 A liquid concentrate bag A for standby 2 And B liquid concentrate bag B 1 Standby B liquid concentrate bag B 2 Is placed on a device higher than the hemodialysis machine by adopting a hanging inversion mode.
Further, the first venous drip cup and the second venous drip cup are respectively provided with a medicine adding port and an air discharging port.
Furthermore, the lower side of the solution bag is provided with a sealing plug connector, and the pipeline can be communicated with the solution bag through the sealing plug connector.
The beneficial effects are that:
(1) According to the invention, 10L of barreled A, B concentrated solution is replaced by sealed bagged concentrated solution, the bagged concentrated solution is 3-8L, preferably 4-6L, and most preferably 5L, and the bagged concentrated solution can be put together with other bagged liquids without special warehouse storage.
(2) Because the concentrated solution is in the sealed bag, the bag body is provided with the plug-in port, and when the sealed bag is used, the pipeline is only required to be connected into the sealed bag through the plug-in port, so that the concentrated solution in the sealed bag can not be polluted. Thereby avoiding the difficult problems that the barreled dialysate barrel cover and the dialysis machine A, B liquid suction device cannot be sealed, and dust and microorganisms can fall into the barrel through the exposed part of the barrel opening to pollute the concentrated liquid in the use process.
(3) Adopts A liquid concentrate bag A 1 A liquid concentrate bag A for standby 2 Liquid B concentrated solution bag B 1 Standby B liquid concentrate bag B 2 And a pipeline for realizing switchable concentrated solution, so that the concentrated solution bag A of the solution A 1 With standby A liquid concentrate bag A 2 Switchable B liquid concentrate bag B 1 And standby B liquid concentrate bag B 2 The device can be switched, so that continuous hemodialysis treatment without stopping is realized, the problem that the treatment is finished in advance due to the change of the disease condition of a patient, and the residual concentrated solution is not allowed to be poured and combined and needs to be discarded, so that the concentrated solution is wasted, and the cost expenditure is reduced.
(4) The dialysis machine is connected after the bagged A liquid or B liquid concentrated liquid is hung in a small volume, the nurse checks the bagged A liquid or B liquid concentrated liquid, the problem that the infusion process cannot be entered due to unstable conductivity caused by the fact that the nurse cannot find the infusion process in time due to the fact that the barreled concentrated liquid is adopted, or the dialysis liquid is used for sucking and alarming, the venous pressure and the transmembrane pressure are changed and the alarm is repeated, and the tension emotion of a patient is generated is avoided.
(5) By adopting two sets of hemodialysis devices and pipelines capable of realizing the switching of the hemodialysis devices, when one of the hemodialysis devices is blocked, the pipeline is switched to the other hemodialysis device to continue stealing, and the problems that the hemodialysis treatment cannot be continued, the hemodialysis treatment is interrupted, the dialysate A and B are scrapped and the like due to the blocking of the hemodialysis devices are solved.
(6) Adopts A liquid concentrate bag A 1 A liquid concentrate bag A for standby 2 Liquid B concentrated solution bag B 1 Standby B liquid concentrate bag B 2 And a pipeline for realizing the switching of the concentrated solution, two hemodialysis devices and a pipeline for realizing the automatic switching of the two hemodialysis devices,can realize continuous hemodialysis without stopping the hemodialysis, and can cope with emergency rescue conditions of patients with whole body organ failure. The hemodialysis patient does not need to be shut down for replacement, nor does the hemodialysis machine, the barreled solution A concentrate and the barreled solution B concentrate need to be prepared again.
Drawings
FIG. 1 is a flow chart of dialysate generation and dialysis
FIG. 2 is a central concentrate supply system
FIG. 3 is a central dialysate supply system
FIG. 4 is a schematic view of the structure of the present invention
FIG. 5 is a schematic view of a hemodialysis machine
Fig. 6 is a schematic diagram of a hemodialysis tube connection structure that enables replacement of hemodialysis patients without stopping.
Detailed Description
Example 1: as shown in fig. 4 and 5, a hemodialysis system for continuously dialyzing an extracorporeal circulation circuit of a switchable concentrate, comprising: a blood circulation system comprising an inlet channel 100, a blood pump 101, a hemodialysis machine 500, and a return channel 103; a dialysate system comprising a concentrate container 200, a concentrate line 201, a reverse osmosis water system 202, a reverse osmosis water line 203, a hemodialysis machine 204, a dialysate intake pump 205, and a dialysate intake line 206; a waste liquid system consisting of a liquid discharge pipeline 301, a liquid discharge pump 302 and a waste liquid container 303; and a fluid infusion system comprising a fluid infusion line 401, a fluid infusion pump 402, and a fluid infusion container 403.
The basic working principle of the reverse osmosis water system is as follows: the raw water is added to the pressure of 6-20 kg by a special high-pressure water pump, so that the raw water permeates the reverse osmosis membrane with the aperture of only 0.0001 microns under the action of the pressure. Chemical ions and bacteria, fungi and virosomes cannot pass through, and are discharged with the wastewater, allowing only water molecules and solvents with a volume of less than 0.0001 microns to pass through. The reverse osmosis water system is a special device for a blood purification center, belongs to the prior art, only uses the reverse osmosis water system, is not innovated and improved, and is not described any more for the specific implementation scheme of preparing the reverse osmosis water by the reverse osmosis water system.
The hemodialysis machine comprises a blood monitoring alarm system and a dialysate supply system. The blood monitoring alarm system comprises a blood pump, a heparin pump, arterial pressure monitoring, air monitoring and the like; the dialysate supply system comprises a temperature control system, a liquid preparation system, a degassing system, a conductivity monitoring system, an ultrafiltration monitoring and blood leakage monitoring system and the like. The working principle is as follows: the concentrated solution for dialysis and the water for dialysis, namely reverse osmosis water, are prepared into qualified dialysate through a dialysate supply system, and solute dispersion, osmosis and ultrafiltration are carried out on the qualified dialysate and the blood of a patient led out by a blood monitoring alarm system through a hemodialyzer; the blood of the patient after the function returns to the patient through the blood monitoring alarm system, and the liquid after the dialysis is discharged from the dialysate supply system as waste liquid; and continuously and circularly reciprocating to complete the whole dialysis process. The invention only uses the hemodialysis machine, the technical improvement of the hemodialysis machine is not carried out, and the principle and the technical scheme of the liquid distribution system of the hemodialysis machine are not described again.
The hemodialysis device is a pipeline and a container for exchanging solutes between blood and dialysate, and is a key part of hemodialysis. The dialyzer mainly comprises a supporting structure and a dialysis membrane, the latter is an important component part of the dialyzer, the dialyzer is a semi-permeable membrane which only allows molecules smaller than the pore diameter of the membrane to pass through, and the membrane material is two modified cellulose membranes and synthetic membranes, and the two membranes can be manufactured into the dialyzer with high flux. The hemodialysis device is a medical consumable, only the hemodialysis device is used, technical improvement is not carried out on the hemodialysis device, and the principle and the technical scheme for carrying out solute exchange on the hemodialysis device are not described again here.
As shown in fig. 5, the hemodialysis machine 500 includes a blood inlet 501, a blood outlet 502, a dialysate inlet 503, and a drain outlet 504.
One end of the blood inlet pipeline 100 is introduced into an artery of a patient, and the other end of the blood inlet pipeline is connected into a blood inlet 501 of the hemodialysis machine 500 after passing through the blood pump 102;
one end of the blood return path 104 is connected to a blood outlet 502 of the hemodialysis machine 500, and the other end is connected to a vein of a patient; arterial blood of a patient flows into the hemodialysis device 500 through the blood inlet pipeline 100, is purified by the hemodialysis device 500, and flows back to a vein of the patient through the blood return pipeline 104;
one end of the concentrated solution pipeline 201 is connected with the concentrated solution container 200, and the other end is connected with the hemodialysis machine 204; one end of the reverse osmosis water pipeline 203 is connected to the reverse osmosis water system 202, and the other end is connected to the hemodialysis machine 204; the dialysate inlet pipe 206 is connected with the dialysate inlet 503;
the concentrated solution is filled in the concentrated solution container 200, the reverse osmosis water system 202 generates reverse osmosis water, the concentrated solution and the reverse osmosis water are proportionally prepared into dialysate through the hemodialysis machine 204, the prepared dialysate flows into the hemodialysis machine 500 through the dialysate inlet pump 205 and the dialysate inlet pipeline 206, and exchanges substances with blood flowing through the hemodialysis machine 500 through dispersion, ultrafiltration, adsorption and convection, so that metabolic wastes in the blood are removed, and the balance of blood electrolyte and acid and alkali is maintained;
one end of the liquid draining pipeline 301 is connected to a liquid draining outlet 504 of the hemodialysis device 500, and the other end is connected to a waste liquid container 303 after passing through a liquid draining pump 302; one end of the fluid infusion pipeline 401 is connected to the fluid infusion container 403, and the other end is connected to the blood return pipeline 104 after passing through the fluid infusion pump 402.
The concentrate container 200 includes a liquid concentrate container a and a liquid concentrate container B; the A liquid concentrated solution container is a solution bag, and comprises an A liquid concentrated solution bag A 1 2001 and Standby A concentrate bag A 2 2002, wherein the B liquid concentrate container is a solution bag and comprises a B liquid concentrate bag B 1 2003 and Standby B concentrate bag B 2 2004；
The concentrated solution pipeline comprises a concentrated solution pipeline A and a concentrated solution pipeline B;
the A concentrate pipeline comprises an A concentrate pipeline main pipe 2011, an A concentrate pipeline first branch 2011-1 and an A concentrate pipeline second branch 2011-2;
also comprises a first breaker 601 and a second breaker 602;
one end of the first branch 2011-1 of the A liquid concentrate pipeline is connected with an A liquid concentrate bag A 1 2001, the other end is connected into a main pipe 2011 of the A liquid concentrate pipeline after passing through a first circuit breaker 601;
one end of the second branch 2011-2 of the A liquid concentrate pipeline is connected with a standby A liquid concentrate bag A 2 2002, the other end is connected into a main pipe 2011 of the A liquid concentrate pipeline after passing through the second circuit breaker 602;
the main pipe 2011 of the liquid A concentrate pipeline is connected into the hemodialysis machine 204;
the B concentrate pipeline comprises a B concentrate pipeline main pipe 2014, a B concentrate pipeline first branch 2014-1 and a B concentrate pipeline second branch 2014-2;
also comprises a third breaker 603 and a fourth breaker 604;
one end of the first branch 2014-1 of the B liquid concentrate pipeline is connected with a B liquid concentrate bag B 1 2003, the other end is connected into a main pipe 2014 of the B liquid concentrate pipeline after passing through a third circuit breaker 603;
one end of the second branch 2014-2 of the B liquid concentrate pipeline is connected with a standby B liquid concentrate bag B 2 2004, the other end is connected into a main pipe 2014 of the B liquid concentrate pipeline after passing through a fourth circuit breaker 604;
the main pipe 2014 of the liquid B concentrate pipeline is connected to the hemodialysis machine 204;
two hemodialysis machines, namely a first hemodialysis machine 501 and a second hemodialysis machine 502;
the dialysate inlet pipeline comprises a dialysate inlet pipeline main pipe 206-1, a dialysate inlet pipeline first branch pipe 206-2 and a dialysate inlet pipeline second branch pipe 206-3, wherein the dialysate inlet pipeline main pipe 206-1 is respectively connected and communicated with the dialysate inlet pipeline first branch pipe 206-2 and the dialysate inlet pipeline second branch pipe 206-3, one end of the dialysate inlet pipeline main pipe 206-1 is connected to the hemodialysis machine 204, the dialysate inlet pipeline first branch pipe 206-2 is connected to the dialysate inlet 503 of the first hemodialysis machine 501 after passing through a fifth circuit breaker 605, and the dialysate inlet pipeline second branch pipe 206-3 is connected to the dialysate inlet 503 of the second hemodialysis machine 502 after passing through a sixth circuit breaker 606;
the blood inlet path comprises a blood inlet path main pipe 100-1, a blood inlet path first branch pipe 100-2 and a blood inlet path second branch pipe 100-3, wherein the blood inlet path main pipe 100-1 is respectively connected and communicated with the blood inlet path first branch pipe 100-2 and the blood inlet path second branch pipe 100-3, the blood inlet path main pipe 100-1 is connected into an artery of a patient after passing through a blood pump 102, the blood inlet path first branch pipe 100-2 is connected into a blood inlet of a first hemodialysis device 501 after passing through a seventh breaker 607, and the blood inlet path second branch pipe 100-3 is connected into a blood inlet of a second hemodialysis device 502 after passing through an eighth breaker 608;
the blood return circuit 104 comprises a blood return circuit main pipe 104-1, a blood return circuit first branch pipe 104-2 and a blood return circuit second branch pipe 104-3, wherein the blood return circuit main pipe 104-1 is respectively connected and communicated with the blood return circuit first branch pipe 104-2 and the blood return circuit second branch pipe 104-3, and the blood return circuit main pipe 104-1 is accessed into a vein of a patient; one end of the first branch pipe 104-2 of the blood circuit is connected to the blood outlet of the first hemodialysis unit 501, and the other end is connected to the main pipe 104-1 of the blood circuit through a ninth breaker 609; one end of the second branch pipe 104-3 of the blood circuit is connected to the blood outlet of the second hemodialysis unit 502, and the other end is connected to the main pipe 104-1 of the blood circuit through a tenth circuit breaker 610;
the liquid discharge pipeline 301 comprises a liquid discharge pipeline main pipe 301-1, a liquid discharge pipeline first branch pipe 301-2 and a liquid discharge pipeline second branch pipe 301-3, wherein the liquid discharge pipeline main pipe 301-1 is respectively connected and communicated with the liquid discharge pipeline first branch pipe 301-2 and the liquid discharge pipeline second branch pipe 301-3; one end of the first branch pipe 301-2 of the liquid discharge pipeline is connected to the liquid discharge outlet 504 of the first hemodialysis device 501, and the other end of the first branch pipe is connected to the main pipe 301-1 of the liquid discharge pipeline after passing through the eleventh circuit breaker 611; one end of the drain pipe second branch 301-3 is connected to the drain outlet 504 of the second hemodialysis unit 502, and the other end is connected to the drain pipe main 301-1 through the twelfth circuit breaker 612, and the drain pipe main 301-1 is connected to the waste liquid container 303 through the drain pump 302.
Further, a first venous drip cup 700-1 is arranged on the main pipe of the A liquid concentrate pipeline, and a second venous drip cup 700-2 is arranged on the main pipe of the B liquid concentrate pipeline.
Further, air alarms 800-1, 800-2, 800-3, 800-4 are respectively arranged on the first branch 2011-2 of the liquid A concentrate pipeline, the second branch 2011-2 of the liquid A concentrate pipeline, the first branch 2014-1 of the liquid B concentrate pipeline and the second branch 2014-2 of the liquid B concentrate pipeline, and the air alarms 800-1, 800-2, 800-3, 800-4 are electrically connected with the hemodialysis machine 204.
Further, the A liquid concentrate bag A 1 2001 and Standby A concentrate bag A 2 2002 are all 2-15L in volume, and the B liquid concentrate bag B 1 2003 and Standby B concentrate bag B 2 2004 are all 2-15L.
Preferably, the A liquid concentrate bag A 1 And a standby A liquid concentrate bag A 2 The volumes of the liquid B and the concentrated liquid bag B are all 5L 1 And a standby B liquid concentrate bag B 2 Is 5L.
Further, A liquid concentrate bag A 1 2001. Standby A liquid concentrate bag A 2 2002, and B liquid concentrate bag B 1 2003. Standby B liquid concentrate bag B 2 2004, placed on the device at a height above the hemodialysis machine 204 in a hanging inverted fashion.
Further, the first intravenous drip cup 700-1 and the second intravenous drip cup 700-2 are respectively provided with a medicine feeding port and an air discharge port.
Furthermore, the lower side of the solution bag is provided with a sealing plug connector, and the pipeline can be communicated with the solution bag through the sealing plug connector.
When blood purification is clinically needed, the method comprises the following steps:
the first step: according to fig. 4, the first hemodialysis unit 501, the second hemodialysis unit 502, the hemodialysis unit 204, the reverse osmosis system 202, the waste liquid container 303, the fluid replacement container 403, and the like are connected, all the circuit breakers are closed, and the replacement fluid is injected into the fluid replacement container.
And a second step of: and opening all the circuit breakers and pre-flushing the pipeline by using normal saline. After the flushing is completed, the second circuit breaker 602, the fourth circuit breaker 604, the sixth circuit breaker 606, the eighth circuit breaker, the tenth circuit breaker 610, and the twelfth circuit breaker 612 are closed.
And a third step of: the A liquid concentrate is packed in a bag A 1 2001. Standby A liquid concentrate bag A 2 2002. Liquid B concentrated solution bag B 1 2003 and Standby B concentrate bag B 2 2004 to the hemodialysis system by plugging in.
Fourth step: access to the patient's artery is provided by access to the vascular access 100, and access to the patient's vein is provided by the vascular return 104.
Fifth step: starting the hemodialysis machine, and opening the A liquid concentrate bag A 1 2001. Liquid B concentrated solution bag B 1 2003. The reverse osmosis water flows into the hemodialysis machine, the hemodialysis machine is proportionally configured into a dialysate, the dialysate flows into the first hemodialysis machine through a pipeline under the action of a pump, and a replacement reaction is carried out on the dialysate and blood flowing through the first hemodialysis machine, so that blood purification is completed, and waste liquid generated in the first hemodialysis machine flows into the waste liquid container 303 through the pipeline under the action of the waste liquid pump. When A liquid concentrate bag A 1 2001 is exhausted, the second circuit breaker 602 is opened and the standby A liquid concentrate bag A 2 The concentrate in 2002 flows into a hemodialysis machine. Closing the first circuit breaker 601 and removing the empty A concentrate bag A 1 New A concentrated solution bag A 1 And (3) replacing. When the standby A liquid concentrate bag A 2 When the concentrate in 2002 is used up, the second breaker 602 is closed, the first breaker 601 is opened, and the concentrate bag B of the concentrate B is filled with the concentrate 1 2003, replacement.
For B liquid concentrate bag B 1 2003. Standby B liquid concentrate bag B 1 2003 is also replaced in the manner described above.
Adopts A liquid concentrate bag A 1 A liquid concentrate bag A for standby 2 Liquid B concentrated solution bag B 1 Standby B liquid concentrate bag B 2 And a pipeline for realizing switchable concentrated solution, so that the concentrated solution bag A of the solution A 1 With standby A liquid concentrate bag A 2 Switchable B liquid concentrate bag B 1 And standby B liquid concentrate bag B 2 The device can be switched, so that continuous hemodialysis treatment without stopping is realized, the problem that the treatment is finished in advance due to the change of the disease condition of a patient, and the residual concentrated solution is not allowed to be poured and combined and needs to be discarded, so that the concentrated solution is wasted, and the cost expenditure is reduced.
A sixth step, when the first hemodialysis machine is blocked, firstly, opening an eighth circuit breaker 608 and a tenth circuit breaker to ensure that the pipeline of the second hemodialysis machine is unobstructed; then, the seventh breaker 607, the ninth breaker 609 are closed, ensuring that the first hemodialyzer line is blocked; finally, the pre-rinsed new first circuit breaker is connected to the blood purification system according to fig. 4. When the second hemodialysis machine is clogged, the first circuit breaker is opened and the second circuit breaker is closed by adopting the operation, and the circulation is performed. By adopting two sets of hemodialysis devices and pipelines capable of realizing the switching of the hemodialysis devices, when one of the hemodialysis devices is blocked, the pipeline is switched to the other hemodialysis device to continue stealing, and the problems that the hemodialysis treatment cannot be continued, the hemodialysis treatment is interrupted, the dialysate A and B are scrapped and the like due to the blocking of the hemodialysis devices are solved.
Example 2: as shown in fig. 6, this embodiment is different from embodiment 1 in that: also included are a second blood inlet line 105 and a second blood circuit 106; the second blood circuit 106 is connected to the blood inlet of the second hemodialysis machine 502 through the blood pump 102 and the thirteenth circuit breaker 613, respectively; the second blood circuit 106 is connected to the blood outlet of the second hemodialysis machine 502 after passing through a fourteenth circuit breaker 614;
the fluid infusion pipeline 401 comprises a fluid infusion pipeline main pipe 401-1, a fluid infusion pipeline first branch pipe 401-2 and a fluid infusion pipeline second branch pipe 401-3; one end of the fluid infusion line main pipe 401-1 is connected to the fluid infusion container 403 after passing through the fluid infusion pump 402, the fluid infusion line first branch pipe 401-2 is connected to the return vessel 104, and the fluid infusion line second branch pipe 401-3 is connected to the second return vessel 106 after passing through the fifteenth breaker 615.
When emergency patients who meet emergency rescue conditions of patients with whole body organ failure are subjected to hemodialysis, the non-emergency patients who are in dialysis are stopped from hemodialysis, and corresponding pipelines are closed. Taking as an example that a non-emergency patient is using a first hemodialyzer for blood purification. The seventh circuit breaker 607, the ninth circuit breaker, the tenth circuit breaker and the sixteenth circuit breaker are closed. The second blood inlet line 105, the second blood return line 106, and the arteries and veins, respectively, of the emergency patient are accessed. By opening the thirteenth circuit breaker 613, the fourteenth circuit breaker and the fifteenth circuit breaker, the switching between the hemodialysis non-emergency patient and the emergency patient can be realized under the condition of no shutdown, and precious time is won for emergency patients in emergency rescue of whole body organ failure patients.
Then, the hemodialysis machine is restarted, and the operation such as pre-flushing of the line is performed, so that the non-emergency patient is moved to a new hemodialysis system to continue hemodialysis.
Claims (8)
1. A switchable concentrate hemodialysis system continuous dialysis extracorporeal circulation circuit comprising:
the blood circulation system consists of a blood inlet pipeline, a blood pump, a hemodialysis device and a blood return pipeline;
the dialysate system consists of a concentrate container, a concentrate pipeline, a reverse osmosis water system, a reverse osmosis water pipeline, a hemodialysis machine, a dialysate liquid inlet pump and a dialysate liquid inlet pipeline;
the waste liquid system consists of a liquid discharge pipeline, a liquid discharge pump and a waste liquid container; the method comprises the steps of,
the fluid infusion system consists of a fluid infusion pipeline, a fluid infusion pump and a fluid infusion container;
the hemodialysis device comprises a blood inlet, a blood outlet, a dialysate inlet and a drain outlet;
one end of the blood inlet pipeline is led into an artery of a patient, and the other end of the blood inlet pipeline is connected into a blood inlet of a hemodialysis device after passing through a blood pump;
one end of the blood return pipeline is connected with a blood outlet of the hemodialysis device, and the other end of the blood return pipeline is connected with a vein of a patient; arterial blood of the patient flows into the hemodialysis device through the blood inlet path, is purified by the hemodialysis device, and flows back to the vein of the patient through the blood return path;
one end of the concentrated solution pipeline is connected with the concentrated solution container, and the other end of the concentrated solution pipeline is connected with the hemodialysis machine; one end of the reverse osmosis water pipeline is connected with a reverse osmosis water system, and the other end of the reverse osmosis water pipeline is connected with a hemodialysis machine; the dialysate inlet pipeline is connected with a dialysate inlet;
one end of the liquid discharge pipeline is connected to a liquid discharge outlet of the hemodialysis device, and the other end of the liquid discharge pipeline is connected to a waste liquid container after passing through a liquid discharge pump;
one end of the fluid infusion pipeline is connected with the fluid infusion container, and the other end of the fluid infusion pipeline is connected with the blood return pipeline after passing through the fluid infusion pump;
the method is characterized in that: the concentrated solution container comprises a concentrated solution container A and a concentrated solution container B; the A liquid concentrated solution container is a solution bag, and comprises an A liquid concentrated solution bag A 1 And standby A liquid concentrationLiquid shrinking bag A 2 The B liquid concentrate container is a solution bag and comprises a B liquid concentrate bag B 1 And a standby B liquid concentrate bag B 2 ；
The concentrated solution pipeline comprises a concentrated solution pipeline A and a concentrated solution pipeline B;
the A liquid concentrate pipeline comprises an A liquid concentrate pipeline main pipe, an A liquid concentrate pipeline first branch and an A liquid concentrate pipeline second branch;
the circuit breaker also comprises a first circuit breaker and a second circuit breaker;
one end of the first branch of the A liquid concentrate pipeline is connected with an A liquid concentrate bag A 1 The other end of the main pipe is connected with the main pipe of the A liquid concentrate pipeline after passing through the first circuit breaker;
one end of the second branch of the A liquid concentrate pipeline is connected with a standby A liquid concentrate bag A 2 The other end of the main pipe is connected with the main pipe of the A liquid concentrate pipeline after passing through a second circuit breaker;
the main pipe of the liquid A concentrated liquid pipeline is connected to a hemodialysis machine;
the B liquid concentrate pipeline comprises a B liquid concentrate pipeline main pipe, a B liquid concentrate pipeline first branch and a B liquid concentrate pipeline second branch;
the circuit further comprises a third circuit breaker and a fourth circuit breaker;
one end of the first branch of the B liquid concentrate pipeline is connected with a B liquid concentrate bag B 1 The other end is connected into a main pipe of the liquid B concentrate pipeline after passing through a third circuit breaker;
one end of the second branch of the B liquid concentrate pipeline is connected with a standby B liquid concentrate bag B 2 The other end is connected into a main pipe of the liquid B concentrate pipeline after passing through a fourth circuit breaker;
b, connecting a main pipe of the liquid concentrate pipeline into a hemodialysis machine;
the number of the hemodialysis devices is two, namely a first hemodialysis device and a second hemodialysis device;
the dialysate inlet pipeline comprises a dialysate inlet pipeline main pipe, a dialysate inlet pipeline first branch pipe and a dialysate inlet pipeline second branch pipe, the dialysate inlet pipeline main pipe is respectively connected and communicated with the dialysate inlet pipeline first branch pipe and the dialysate inlet pipeline second branch pipe, one end of the dialysate inlet pipeline main pipe is connected with the hemodialysis machine, the dialysate inlet pipeline first branch pipe is connected with a dialysate inlet of the first hemodialysis machine after passing through a fifth circuit breaker, and the dialysate inlet pipeline second branch pipe is connected with a dialysate inlet of the second hemodialysis machine after passing through a sixth circuit breaker;
the blood inlet pipeline comprises a blood inlet pipeline main pipe, a blood inlet pipeline first branch pipe and a blood inlet pipeline second branch pipe, the blood inlet pipeline main pipe is respectively connected and communicated with the blood inlet pipeline first branch pipe and the blood inlet pipeline second branch pipe, the blood inlet pipeline main pipe is connected to an artery of a patient after passing through a blood pump, the blood inlet pipeline first branch pipe is connected to a blood inlet of a first hemodialysis device after passing through a seventh circuit breaker, and the blood inlet pipeline second branch pipe is connected to a blood inlet of a second hemodialysis device after passing through an eighth circuit breaker;
the blood return pipeline comprises a blood return pipeline main pipe, a first branch pipe of the blood return pipeline and a second branch pipe of the blood return pipeline, wherein the blood return pipeline main pipe is respectively connected and communicated with the first branch pipe of the blood return pipeline and the second branch pipe of the blood return pipeline, and the blood return pipeline main pipe is connected into a vein of a patient; one end of the first branch pipe of the blood circuit is connected to the blood outlet of the first hemodialysis device, and the other end of the first branch pipe of the blood circuit is connected to the main pipe of the blood circuit after passing through the ninth circuit breaker; one end of the second branch pipe of the blood circuit is connected with the blood outlet of the second hemodialysis device, and the other end of the second branch pipe of the blood circuit is connected with the main pipe of the blood circuit after the tenth circuit breaker;
the liquid discharge pipeline comprises a liquid discharge pipeline main pipe, a liquid discharge pipeline first branch pipe and a liquid discharge pipeline second branch pipe, and the liquid discharge pipeline main pipe is respectively connected and communicated with the liquid discharge pipeline first branch pipe and the liquid discharge pipeline second branch pipe; one end of the first branch pipe of the liquid discharge pipeline is connected to a liquid discharge outlet of the first hemodialysis device, and the other end of the first branch pipe of the liquid discharge pipeline is connected to a main pipe of the liquid discharge pipeline after passing through an eleventh circuit breaker; one end of the second branch pipe of the liquid discharge pipeline is connected to a liquid discharge outlet of the second hemodialysis device, the other end of the second branch pipe of the liquid discharge pipeline is connected to a main pipe of the liquid discharge pipeline after passing through a twelfth circuit breaker, and the main pipe of the liquid discharge pipeline is connected to a waste liquid container after passing through a liquid discharge pump;
the device also comprises a second blood inlet pipeline and a second blood return pipeline; the second blood circuit is connected to the blood inlet of the second hemodialysis device after passing through the blood pump and the thirteenth circuit breaker respectively; the second blood circuit is connected to the blood outlet of the second hemodialysis device after passing through the fourteenth circuit breaker;
the fluid infusion pipeline comprises a fluid infusion pipeline main pipe, a fluid infusion pipeline first branch pipe and a fluid infusion pipeline second branch pipe, one end of the fluid infusion pipeline main pipe is connected to the fluid infusion container after passing through the fluid infusion pump, the fluid infusion pipeline first branch pipe is connected to the return vessel circuit, and the fluid infusion pipeline second branch pipe is connected to the second return vessel circuit after passing through the fifteenth circuit breaker.
2. The switchable concentrate hemodialysis system continuous dialysis extracorporeal circulation circuit of claim 1, wherein: a first venous drip cup is arranged on the main pipe of the liquid A concentrated solution pipeline, and a second venous drip cup is arranged on the main pipe of the liquid B concentrated solution pipeline.
3. The switchable concentrate hemodialysis system continuous dialysis extracorporeal circulation circuit of claim 1, wherein: an air alarm is arranged on the first branch of the A liquid concentrate pipeline, the second branch of the A liquid concentrate pipeline, the first branch of the B liquid concentrate pipeline and the second branch of the B liquid concentrate pipeline respectively, and the air alarm is electrically connected with the hemodialysis machine.
4. The switchable concentrate hemodialysis system continuous dialysis extracorporeal circulation circuit of claim 1, wherein: the A liquid concentrate bag A 1 And a standby A liquid concentrate bag A 2 The volumes of the liquid B and the concentrated liquid bag B are all 2-15L 1 And a standby B liquid concentrate bag B 2 The volumes of (2) and (15) L.
5. The switchable concentrate hemodialysis system continuous dialysis extracorporeal circulation circuit of claim 1, wherein: the A liquid concentrate bag A 1 And a standby A liquid concentrate bag A 2 The volumes of the liquid B and the concentrated liquid bag B are all 5L 1 And a standby B liquid concentrate bag B 2 Is 5L.
6. The switchable concentrate hemodialysis system of claim 1, continuousDialysis extracorporeal circulation pipeline, its characterized in that: a liquid concentrate bag A 1 A liquid concentrate bag A for standby 2 And B liquid concentrate bag B 1 Standby B liquid concentrate bag B 2 Is placed on a device higher than the hemodialysis machine by adopting a hanging inversion mode.
7. The switchable concentrate hemodialysis system continuous dialysis extracorporeal circulation circuit of claim 2, wherein: the first intravenous drip cup and the second intravenous drip cup are respectively provided with a medicine adding port and an air discharging port.
8. The switchable concentrate hemodialysis system continuous dialysis extracorporeal circulation circuit of claim 1, wherein: the lower side of the solution bag is provided with a sealing plug connector, and the pipeline can be communicated with the solution bag through the sealing plug connector.
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| CN102958547A (en) * | 2010-06-25 | 2013-03-06 | 尼普洛株式会社 | Hemodialysis device |
| CN206566276U (en) * | 2016-11-18 | 2017-10-20 | 张仲华 | Emergent blood back pipeline and dialysis pipeline for hemodialysis |
| CN214969897U (en) * | 2021-01-21 | 2021-12-03 | 金华市中心医院 | Multifunctional monitoring device for hemodialysis machine pipeline |
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| FR2779964B1 (en) * | 1998-06-17 | 2000-09-15 | Internova International Innova | DIALYSIS MACHINE, PARTICULARLY FOR HOME USE |
| CN206577183U (en) * | 2016-06-11 | 2017-10-24 | 赵晓玲 | The plasmapheresis device extracorporeal circulation pipeline of changeable blood separator |
| CN208641386U (en) * | 2017-10-26 | 2019-03-26 | 胡倩倩 | A kind of blood dialysis circuit pipe |
| CN112933316A (en) * | 2021-02-04 | 2021-06-11 | 青岛大学附属医院 | Hemodialysis device |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102958547A (en) * | 2010-06-25 | 2013-03-06 | 尼普洛株式会社 | Hemodialysis device |
| EP2586474A1 (en) * | 2010-06-25 | 2013-05-01 | Nipro Corporation | Hemodialysis device |
| CN206566276U (en) * | 2016-11-18 | 2017-10-20 | 张仲华 | Emergent blood back pipeline and dialysis pipeline for hemodialysis |
| CN214969897U (en) * | 2021-01-21 | 2021-12-03 | 金华市中心医院 | Multifunctional monitoring device for hemodialysis machine pipeline |
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