CN114247893A - Method for manufacturing metal powder and application thereof - Google Patents

Method for manufacturing metal powder and application thereof Download PDF

Info

Publication number
CN114247893A
CN114247893A CN202210169867.4A CN202210169867A CN114247893A CN 114247893 A CN114247893 A CN 114247893A CN 202210169867 A CN202210169867 A CN 202210169867A CN 114247893 A CN114247893 A CN 114247893A
Authority
CN
China
Prior art keywords
powder
spraying
metal
metal powder
magnesium alloy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
CN202210169867.4A
Other languages
Chinese (zh)
Other versions
CN114247893B (en
Inventor
王荣浩
程波
宰红艳
余文静
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Affiliated Hospital of Southwest Medical University
Original Assignee
Affiliated Hospital of Southwest Medical University
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Affiliated Hospital of Southwest Medical University filed Critical Affiliated Hospital of Southwest Medical University
Priority to CN202210169867.4A priority Critical patent/CN114247893B/en
Publication of CN114247893A publication Critical patent/CN114247893A/en
Application granted granted Critical
Publication of CN114247893B publication Critical patent/CN114247893B/en
Expired - Fee Related legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B22—CASTING; POWDER METALLURGY
    • B22F—WORKING METALLIC POWDER; MANUFACTURE OF ARTICLES FROM METALLIC POWDER; MAKING METALLIC POWDER; APPARATUS OR DEVICES SPECIALLY ADAPTED FOR METALLIC POWDER
    • B22F9/00—Making metallic powder or suspensions thereof
    • B22F9/02—Making metallic powder or suspensions thereof using physical processes
    • B22F9/06—Making metallic powder or suspensions thereof using physical processes starting from liquid material
    • B22F9/08—Making metallic powder or suspensions thereof using physical processes starting from liquid material by casting, e.g. through sieves or in water, by atomising or spraying
    • B22F9/082—Making metallic powder or suspensions thereof using physical processes starting from liquid material by casting, e.g. through sieves or in water, by atomising or spraying atomising using a fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A61L27/04—Metals or alloys
    • A61L27/047—Other specific metals or alloys not covered by A61L27/042 - A61L27/045 or A61L27/06
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/28—Materials for coating prostheses
    • A61L27/30—Inorganic materials
    • A61L27/306—Other specific inorganic materials not covered by A61L27/303 - A61L27/32
    • C—CHEMISTRY; METALLURGY
    • C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
    • C22C—ALLOYS
    • C22C16/00—Alloys based on zirconium
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C4/00—Coating by spraying the coating material in the molten state, e.g. by flame, plasma or electric discharge
    • C23C4/04—Coating by spraying the coating material in the molten state, e.g. by flame, plasma or electric discharge characterised by the coating material
    • C23C4/06—Metallic material
    • C23C4/08—Metallic material containing only metal elements
    • C—CHEMISTRY; METALLURGY
    • C23—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; CHEMICAL SURFACE TREATMENT; DIFFUSION TREATMENT OF METALLIC MATERIAL; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL; INHIBITING CORROSION OF METALLIC MATERIAL OR INCRUSTATION IN GENERAL
    • C23C—COATING METALLIC MATERIAL; COATING MATERIAL WITH METALLIC MATERIAL; SURFACE TREATMENT OF METALLIC MATERIAL BY DIFFUSION INTO THE SURFACE, BY CHEMICAL CONVERSION OR SUBSTITUTION; COATING BY VACUUM EVAPORATION, BY SPUTTERING, BY ION IMPLANTATION OR BY CHEMICAL VAPOUR DEPOSITION, IN GENERAL
    • C23C4/00—Coating by spraying the coating material in the molten state, e.g. by flame, plasma or electric discharge
    • C23C4/12—Coating by spraying the coating material in the molten state, e.g. by flame, plasma or electric discharge characterised by the method of spraying
    • C23C4/134—Plasma spraying

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Materials Engineering (AREA)
  • Plasma & Fusion (AREA)
  • Physics & Mathematics (AREA)
  • Mechanical Engineering (AREA)
  • Metallurgy (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Manufacture Of Metal Powder And Suspensions Thereof (AREA)

Abstract

The invention relates to a method for producing metal powder and the use thereof. In order to improve the corrosion resistance of the medical magnesium alloy material, the ZrTiFeAlY composite coating is formed on the surface of the medical magnesium alloy material by a thermal spraying process. Researches show that the ZrTiFeAlY composite coating can obviously improve the corrosion resistance of the medical magnesium alloy, wherein the rare earth element Y is beneficial to improving the biocompatibility of the composite material, but the corrosion resistance of the composite material is reduced due to excessive rare earth elements. In addition, compared with the traditional method of directly mixing metal element powder for thermal spraying, the thermal spraying powder raw material prepared by the atomization powder preparation method is more favorable for improving the comprehensive performance of the composite coating.

Description

Method for manufacturing metal powder and application thereof
Technical Field
The invention relates to the field of metal powder manufacturing, in particular to a manufacturing method and application of metal powder.
Background
Currently, metal implant materials widely used in clinical applications include stainless steel, cobalt-chromium alloys, titanium alloys, and magnesium alloys. The magnesium alloy has good mechanical compatibility, high specific strength and specific stiffness, the density is close to that of natural bones, the elastic modulus is 41-45GPa and is more close to that of human bones, the stress shielding effect can be effectively relieved, the growth and healing of the bones are promoted, and the occurrence of secondary fracture is prevented.
However, the standard electrode potential of magnesium is very low, is susceptible to corrosion, and has a P-B value of 0.8, and does not allow the formation of an effective protective oxide film, particularly Cl in body fluids-Can accelerate the corrosion of the magnesium alloy, leads the implanted material to have serious corrosion before the body is not cured due to the higher degradation rate, reduces the mechanical property and the stability of the material and leads the material to lose efficacy. In view of the above, how to improve the corrosion resistance of the medical magnesium alloy is a problem to be solved urgently.
Disclosure of Invention
Aiming at the problems in the prior art, the invention aims to provide a manufacturing method of metal powder, and the metal powder is sprayed on the surface of the medical magnesium alloy through a thermal spraying process so as to improve the corrosion resistance of the medical magnesium alloy.
A method of manufacturing a metal powder, comprising the steps of:
accurately weighing zirconium powder, titanium powder, iron powder, aluminum powder and yttrium powder according to the weight ratio, putting the weighed materials into a smelting furnace, and smelting at 1900-2000 ℃;
introducing the obtained metal melt into a preheated tundish;
enabling the metal melt to flow out of a nozzle of a tundish, and obtaining a metal powder material by an atomization powder making method under the protection of high-pressure inert gas;
the powder material with a particle size of 50 to 150 μm is obtained by sieving.
Preferably, the weight ratio of the zirconium powder, the titanium powder, the iron powder, the aluminum powder and the yttrium powder is 60: 10: 5-20.
Furthermore, the invention also provides application of the metal powder, wherein the metal powder is prepared by the preparation method, and the ZrTiFeAlY composite coating is formed by spraying the metal powder on the surface of the medical material by adopting a thermal spraying process.
Preferably, the medical material is medical magnesium alloy.
Preferably, the thermal spray process is plasma spray.
Preferably, the plasma spraying process conditions are as follows: the spraying voltage is 60-80V, the spraying current is 350-400A, the spraying distance is 50-60mm, and the powder feeding speed is 30-35 r/min.
Preferably, the plasma spraying process conditions are as follows: the spraying voltage is 80V, the spraying current is 400A, the spraying distance is 50mm, and the powder feeding speed is 30 r/min.
In order to improve the corrosion resistance of the medical magnesium alloy material, the ZrTiFeAlY composite coating is formed on the surface of the medical magnesium alloy material by a thermal spraying process. Researches show that the ZrTiFeAlY composite coating can obviously improve the corrosion resistance of the medical magnesium alloy, wherein the rare earth element Y is beneficial to improving the biocompatibility of the composite material, but the corrosion resistance of the composite material is reduced due to excessive rare earth elements. In addition, compared with the traditional method of directly mixing metal element powder for thermal spraying, the thermal spraying powder raw material prepared by the atomization powder preparation method is more favorable for improving the comprehensive performance of the composite coating.
Detailed Description
The technical effects of the present invention are demonstrated below by specific examples, but the embodiments of the present invention are not limited thereto.
Example 1
Accurately weighing zirconium powder, titanium powder, iron powder, aluminum powder and yttrium powder according to the weight ratio of 60: 10: 5, putting the weighed materials into a smelting furnace, and smelting at 1900 ℃; introducing the obtained metal melt into a preheated tundish; enabling the metal melt to flow out of a nozzle of a tundish, and obtaining a metal powder material by an atomization powder making method under the protection of high-pressure inert gas; finally, the powder material with the particle size of 50-150 μm is obtained by sieving.
Example 2
Accurately weighing zirconium powder, titanium powder, iron powder, aluminum powder and yttrium powder according to the weight ratio of 60: 10: 8, putting the weighed materials into a smelting furnace, and smelting at 1900 ℃; introducing the obtained metal melt into a preheated tundish; enabling the metal melt to flow out of a nozzle of a tundish, and obtaining a metal powder material by an atomization powder making method under the protection of high-pressure inert gas; finally, the powder material with the particle size of 50-150 μm is obtained by sieving.
Example 3
Accurately weighing zirconium powder, titanium powder, iron powder, aluminum powder and yttrium powder according to the weight ratio of 60: 10, putting into a smelting furnace, and smelting at 1900 ℃; introducing the obtained metal melt into a preheated tundish; enabling the metal melt to flow out of a nozzle of a tundish, and obtaining a metal powder material by an atomization powder making method under the protection of high-pressure inert gas; finally, the powder material with the particle size of 50-150 μm is obtained by sieving.
Example 4
Accurately weighing zirconium powder, titanium powder, iron powder, aluminum powder and yttrium powder according to the weight ratio of 60: 10: 13, putting the weighed materials into a smelting furnace, and smelting at 1900 ℃; introducing the obtained metal melt into a preheated tundish; enabling the metal melt to flow out of a nozzle of a tundish, and obtaining a metal powder material by an atomization powder making method under the protection of high-pressure inert gas; finally, the powder material with the particle size of 50-150 μm is obtained by sieving.
Example 5
Accurately weighing zirconium powder, titanium powder, iron powder, aluminum powder and yttrium powder according to the weight ratio of 60: 10: 16, putting the weighed materials into a smelting furnace, and smelting at 1900 ℃; introducing the obtained metal melt into a preheated tundish; enabling the metal melt to flow out of a nozzle of a tundish, and obtaining a metal powder material by an atomization powder making method under the protection of high-pressure inert gas; finally, the powder material with the particle size of 50-150 μm is obtained by sieving.
Example 6
Accurately weighing zirconium powder, titanium powder, iron powder, aluminum powder and yttrium powder according to the weight ratio of 60: 10: 20, putting into a smelting furnace, and smelting at 1900 ℃; introducing the obtained metal melt into a preheated tundish; enabling the metal melt to flow out of a nozzle of a tundish, and obtaining a metal powder material by an atomization powder making method under the protection of high-pressure inert gas; finally, the powder material with the particle size of 50-150 μm is obtained by sieving.
Comparative example 1
Accurately weighing zirconium powder, titanium powder, iron powder, aluminum powder and yttrium powder according to the weight ratio of 60: 10: 13, putting the weighed materials into a smelting furnace, and smelting at 1900 ℃; introducing the obtained metal melt into a preheated tundish; and (3) enabling the molten metal to flow out from a nozzle of the tundish, and obtaining the metal powder material by an atomization powder making method under the protection of high-pressure inert gas.
Comparative example 2
Accurately weighing zirconium powder, titanium powder, iron powder and aluminum powder according to the weight ratio of 60: 10, putting into a smelting furnace, and smelting at 1900 ℃; introducing the obtained metal melt into a preheated tundish; enabling the metal melt to flow out of a nozzle of a tundish, and obtaining a metal powder material by an atomization powder making method under the protection of high-pressure inert gas; finally, the powder material with the particle size of 50-150 μm is obtained by sieving.
Comparative example 3
Accurately weighing zirconium powder, titanium powder, iron powder, aluminum powder and yttrium powder according to the weight ratio of 60: 10: 30, putting the weighed materials into a smelting furnace, and smelting at 1900 ℃; introducing the obtained metal melt into a preheated tundish; enabling the metal melt to flow out of a nozzle of a tundish, and obtaining a metal powder material by an atomization powder making method under the protection of high-pressure inert gas; finally, the powder material with the particle size of 50-150 μm is obtained by sieving.
Next, the metal powder materials in examples 1 to 6 and comparative examples 1 to 3 were sprayed on the surface of the medical magnesium alloy by a plasma spraying process to form a composite coating, and the specific method was: the medical magnesium alloy substrate is placed into plasma spraying equipment, the equipment is preheated after a power supply is turned on, spraying can be started after preheating is completed, wherein the spraying voltage is 80V, the spraying current is 400A, the spraying distance is 50mm, the powder feeding rate is 30r/min, and a ZrTiFeAlY composite coating can be formed on the surface of the medical magnesium alloy after plasma spraying is completed.
The corrosion resistance and biocompatibility of each of the above samples were evaluated as follows.
The hemocompatibility of each sample was evaluated by a hemolysis test, which is based on the following principle: the sample is directly contacted with blood, and the amount of hemoglobin released after rupture of erythrocyte membrane is measured to detect the degree of hemolysis in vitro of each sample. The absorption wavelength of hemoglobin is 545nm, and its concentration can be detected by a spectrophotometer. The specific operation steps are as follows:
(1) blood is collected from the heart of a healthy rabbit by 100mL, and 2% potassium oxalate by 5mL is added to prepare fresh anticoagulation blood. And taking 40mL of anticoagulation blood, and adding 50mL of 0.9% sodium chloride injection for dilution.
(2) Taking 3 silicified test tubes, loading a test sample and 10mL of sodium chloride injection into one test tube, taking a blank of one test tube as a negative control group, adding 10mL of sodium chloride normal saline, and taking a blank of the other test tube as a positive control group, and respectively adding 10mL of distilled water.
(3) All the test tubes are kept constant in a water bath at 37 ℃ for 30min, 5mL of anticoagulated rabbit blood is added respectively, and the temperature is kept at 37 ℃ for 60 min.
(4) The supernatant of the test tube was taken and the absorbance was measured at 545 nm. Three replicates of each sample were run and averaged.
The hemolysis rate is calculated as follows:
hemolysis ratio (%) = (sample average absorbance-absorbance in negative group)/(absorbance in positive group-absorbance in negative group) × 100
The corrosion resistance of each sample was evaluated by measuring the self-corrosion current density in Simulated Body Fluid (SBF), and five parallel tests were performed for each set of experiments, and the average value was taken.
The experimental results of the samples are shown in table 1, and the medical magnesium alloy without any treatment is used as a blank control group.
TABLE 1 self-etching Current Density and hemolysis ratio of each sample
Numbering Percent of hemolysis% Self-corrosion current density mA/cm2
Example 1 4.5 0.0127
Example 2 3.3 0.0204
Example 3 3.9 0.0215
Example 4 2.5 0.0217
Example 5 1.0 0.0315
Example 6 1.4 0.0526
Comparative example 1 3.1 0.0656
Comparative example 2 7.7 0.0263
Comparative example 3 1.9 0.1760
Blank control group 4.7 0.3290
As can be seen from Table 1, the incorporation of a suitable amount of yttrium, a rare earth element, into the composite coating is beneficial to improve the biocompatibility, but excessive amounts of yttrium (as in comparative example 3) can lead to a reduction in the corrosion resistance of the composite coating. And the screening process of the metal alloy powder is beneficial to improving the comprehensive performance of the composite coating.
The above description is only a preferred embodiment of the present invention, and it should be noted that, for those skilled in the art, several modifications and variations can be made without departing from the technical principle of the present invention, and these modifications and variations should also be regarded as the protection scope of the present invention.

Claims (7)

1. A method of manufacturing a metal powder, comprising the steps of:
accurately weighing zirconium powder, titanium powder, iron powder, aluminum powder and yttrium powder according to the weight ratio, putting the weighed materials into a smelting furnace, and smelting at 1900-2000 ℃;
introducing the obtained metal melt into a preheated tundish;
enabling the metal melt to flow out of a nozzle of a tundish, and obtaining a metal powder material by an atomization powder making method under the protection of high-pressure inert gas;
the powder material with a particle size of 50 to 150 μm is obtained by sieving.
2. The method according to claim 1, wherein the weight ratio of the zirconium powder, the titanium powder, the iron powder, the aluminum powder and the yttrium powder is 60: 10: 5-20.
3. The application of the metal powder prepared by the manufacturing method of claim 1 or 2 is characterized in that the ZrTiFeAlY composite coating is formed by spraying the metal powder on the surface of a medical material by a thermal spraying process.
4. Use of a metal powder according to claim 3, wherein the medical material is a medical magnesium alloy.
5. Use of a metal powder according to claim 3, wherein the thermal spraying process is plasma spraying.
6. Use of a metal powder according to claim 5, wherein the plasma spraying process conditions are: the spraying voltage is 60-80V, the spraying current is 350-400A, the spraying distance is 50-60mm, and the powder feeding speed is 30-35 r/min.
7. Use of a metal powder according to claim 6, wherein the plasma spraying process conditions are: the spraying voltage is 80V, the spraying current is 400A, the spraying distance is 50mm, and the powder feeding speed is 30 r/min.
CN202210169867.4A 2022-02-24 2022-02-24 Application of metal powder in field of medical materials Expired - Fee Related CN114247893B (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210169867.4A CN114247893B (en) 2022-02-24 2022-02-24 Application of metal powder in field of medical materials

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210169867.4A CN114247893B (en) 2022-02-24 2022-02-24 Application of metal powder in field of medical materials

Publications (2)

Publication Number Publication Date
CN114247893A true CN114247893A (en) 2022-03-29
CN114247893B CN114247893B (en) 2022-05-17

Family

ID=80797044

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210169867.4A Expired - Fee Related CN114247893B (en) 2022-02-24 2022-02-24 Application of metal powder in field of medical materials

Country Status (1)

Country Link
CN (1) CN114247893B (en)

Citations (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006081896A (en) * 2004-08-20 2006-03-30 National Institute Of Advanced Industrial & Technology Transparent titanium-coated biocompatible material
CN101961507A (en) * 2010-10-26 2011-02-02 四川材料与工艺研究所 Medicinal implant and preparation method thereof
CN102560197A (en) * 2011-12-15 2012-07-11 北京矿冶研究总院 Alloy powder for high-temperature marine corrosion resistant thermal spraying and preparation method thereof
CN104561878A (en) * 2013-10-29 2015-04-29 比亚迪股份有限公司 High-entropy alloy powder for spray coating and preparation method thereof, as well as composite material and preparation method thereof
CN105063420A (en) * 2015-08-06 2015-11-18 陆春玲 Preparation method for medical titanium alloy bar with strong antibacterial ability
CN105200413A (en) * 2015-09-14 2015-12-30 山东科技大学 Preparation method of Ca-P-Sn composite coating layer on surface of magnesium alloy
CN105458271A (en) * 2016-01-12 2016-04-06 中南大学 Titanium alloy composite material coated with composite coating and preparation method and application of titanium alloy composite material
CN105458274A (en) * 2015-12-30 2016-04-06 中国航空工业集团公司北京航空材料研究院 Ball milling preparation method for nickel-based high-temperature graphene alloy powder
CN105624496A (en) * 2015-12-28 2016-06-01 青岛博泰美联化工技术有限公司 Bone nail and preparation method
CN106811724A (en) * 2017-01-18 2017-06-09 太原工业学院 A kind of corrosion-resistant high-entropy alloy coating of Mg alloy surface and preparation method thereof
US20170281827A1 (en) * 2016-03-18 2017-10-05 Dean Baker Material compositions, apparatus and method of manufacturing composites for medical implants or manufacturing of implant product, and products of the same
CN107557633A (en) * 2017-08-10 2018-01-09 北京航空航天大学 A kind of microalloying medical degradable magnesium alloy and preparation method thereof
CN108149238A (en) * 2017-12-27 2018-06-12 宁波远欣石化有限公司 A kind of heat-insulated protective coating of metal material and preparation method thereof
CN108465127A (en) * 2018-03-28 2018-08-31 济南大学 The method of magnesium alloy bone plate surface prepares coating
US10858296B1 (en) * 2012-06-27 2020-12-08 James J. Myrick Energetics, compositions, manufacture and applications
CN112301304A (en) * 2020-09-24 2021-02-02 山东鲁银新材料科技有限公司 Preparation method and application of near-spherical metal powder for anticorrosive repair spraying
EP3782657A1 (en) * 2019-08-21 2021-02-24 Bioretec Oy Composite material, implant comprising thereof, use of the composite material and method for preparing a medical device
CN113445041A (en) * 2021-07-15 2021-09-28 山东理工大学 Preparation method of low-cost light high-entropy alloy/aluminum oxide composite coating on surface of magnesium alloy
CN113846282A (en) * 2021-09-24 2021-12-28 广东省科学院新材料研究所 Medical stainless steel with Zn-Cu alloy coating, preparation method and application
WO2022002737A1 (en) * 2020-07-03 2022-01-06 W&M Gmbh Composite material, process for producing a composite material and medical device based on composite material

Patent Citations (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006081896A (en) * 2004-08-20 2006-03-30 National Institute Of Advanced Industrial & Technology Transparent titanium-coated biocompatible material
CN101961507A (en) * 2010-10-26 2011-02-02 四川材料与工艺研究所 Medicinal implant and preparation method thereof
CN102560197A (en) * 2011-12-15 2012-07-11 北京矿冶研究总院 Alloy powder for high-temperature marine corrosion resistant thermal spraying and preparation method thereof
US10858296B1 (en) * 2012-06-27 2020-12-08 James J. Myrick Energetics, compositions, manufacture and applications
CN104561878A (en) * 2013-10-29 2015-04-29 比亚迪股份有限公司 High-entropy alloy powder for spray coating and preparation method thereof, as well as composite material and preparation method thereof
CN105063420A (en) * 2015-08-06 2015-11-18 陆春玲 Preparation method for medical titanium alloy bar with strong antibacterial ability
CN105200413A (en) * 2015-09-14 2015-12-30 山东科技大学 Preparation method of Ca-P-Sn composite coating layer on surface of magnesium alloy
CN105624496A (en) * 2015-12-28 2016-06-01 青岛博泰美联化工技术有限公司 Bone nail and preparation method
CN105458274A (en) * 2015-12-30 2016-04-06 中国航空工业集团公司北京航空材料研究院 Ball milling preparation method for nickel-based high-temperature graphene alloy powder
CN105458271A (en) * 2016-01-12 2016-04-06 中南大学 Titanium alloy composite material coated with composite coating and preparation method and application of titanium alloy composite material
US20170281827A1 (en) * 2016-03-18 2017-10-05 Dean Baker Material compositions, apparatus and method of manufacturing composites for medical implants or manufacturing of implant product, and products of the same
CN106811724A (en) * 2017-01-18 2017-06-09 太原工业学院 A kind of corrosion-resistant high-entropy alloy coating of Mg alloy surface and preparation method thereof
CN107557633A (en) * 2017-08-10 2018-01-09 北京航空航天大学 A kind of microalloying medical degradable magnesium alloy and preparation method thereof
CN108149238A (en) * 2017-12-27 2018-06-12 宁波远欣石化有限公司 A kind of heat-insulated protective coating of metal material and preparation method thereof
CN108465127A (en) * 2018-03-28 2018-08-31 济南大学 The method of magnesium alloy bone plate surface prepares coating
EP3782657A1 (en) * 2019-08-21 2021-02-24 Bioretec Oy Composite material, implant comprising thereof, use of the composite material and method for preparing a medical device
WO2022002737A1 (en) * 2020-07-03 2022-01-06 W&M Gmbh Composite material, process for producing a composite material and medical device based on composite material
CN112301304A (en) * 2020-09-24 2021-02-02 山东鲁银新材料科技有限公司 Preparation method and application of near-spherical metal powder for anticorrosive repair spraying
CN113445041A (en) * 2021-07-15 2021-09-28 山东理工大学 Preparation method of low-cost light high-entropy alloy/aluminum oxide composite coating on surface of magnesium alloy
CN113846282A (en) * 2021-09-24 2021-12-28 广东省科学院新材料研究所 Medical stainless steel with Zn-Cu alloy coating, preparation method and application

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
KAI-MING HAN: "Zr-Ti-Al-Fe-Cu bulk metallic glasses for biomedical device application", 《RARE METALS》 *
刘雪: "医用镁合金表面激光熔覆Zr60Ti6Cu19Fe5Al10非晶涂层", 《中国优秀硕士学位论文全文数据库 工程科技I辑》 *
潘复生: "《中国战略性新兴产业 新材料 新型合金材料 镁合金》", 31 October 2017, 北京：中国铁道出版社 *
罗洪杰: "《有色金属先进材料及其制备技术学术研讨会论文集》", 31 December 2016, 沈阳：东北大学出版社 *
马尧: "钇含量对CoNiCrAlY合金微观组织的影响", 《热喷涂技术》 *

Also Published As

Publication number Publication date
CN114247893B (en) 2022-05-17

Similar Documents

Publication Publication Date Title
US20210394269A1 (en) 4d printing method for in-situ regulation of functional properties of nickel-titanium alloy and use thereof
Ito et al. In vitro biocompatibility, mechanical properties, and corrosion resistance of Ti Zr Nb Ta Pd and Ti Sn Nb Ta Pd alloys
KR100971649B1 (en) Beta-based titanium alloy with low elastic modulus
Modig et al. Pulmonary microembolism during intramedullary orthopaedic trauma
US20230338615A1 (en) Oxide layer-containing zirconium-niobium alloy tibial plateau prosthesis having bone trabecula and preparation method
CN102505089A (en) Biodegradable magnesium-lithium alloy material and preparation method thereof
CN106086562A (en) Biological degradable in vivo anastomosis staple and production technology thereof
CN114247893B (en) Application of metal powder in field of medical materials
CN110433329B (en) High-strength, low-elastic-modulus and non-toxic titanium-niobium-zirconium alloy dental implant
Mat-Baharin et al. Influence of alloying elements on cellular response and in-vitro corrosion behavior of titanium-molybdenum-chromium alloys for implant materials
CN106606801A (en) Zn-ZnO zinc alloy and its preparation method and application
CN104962779A (en) Ti6Al4V alloy and orthopaedic implant prepared from alloy
CN110090318B (en) Fe-Mn porous alloy material and preparation method and application thereof
CN109528633B (en) Inosine injection and preparation method thereof
CN107115564A (en) A kind of method for preparing the pure titanium implant material for carrying cerium oxide nano particle functional film layer
Xu et al. Effects of calcium glycerophosphate concentration on micro-arc oxidation coating of Mg alloy
Kawanabe et al. Acute nephrotoxicity as an adverse effect after intraperitoneal injection of massive amounts of bioactive ceramic powders in mice and rats
CN112620626B (en) Forming method of bone induction type titanium alloy bone implant with high antibacterial property
CN108677099A (en) Medical degradable Fe-Mn-Ag alloy materials and preparation and application
CN104042350A (en) Implant with plasma coated nano-zirconium oxide coating and preparation method thereof
KR20080105304A (en) Tin coating method of alloy for dental implants
CN109550077B (en) Preparation method of medical Ti6Al4V artificial implant
CN114686871B (en) Preparation method of biological porous coating based on powder oxygenation design
CN115300676A (en) Medicine-carrying medical instrument and preparation method thereof
CN116815270A (en) Vascular stent and preparation method thereof

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
GR01 Patent grant
GR01 Patent grant
CF01 Termination of patent right due to non-payment of annual fee

Granted publication date: 20220517

CF01 Termination of patent right due to non-payment of annual fee