CN114231274A - 一种铝离子传感分子材料及其应用 - Google Patents
一种铝离子传感分子材料及其应用 Download PDFInfo
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Abstract
本发明涉及化学材料技术领域,特别是一种铝离子传感分子材料及其应用,与现有技术相比,该铝离子传感分子材料由基本单位和四个取代基团组成。基本单位由邻苯酚基苯磺酸或邻苯酚基苯磺酸根组成,在苯酚羟基邻位有一个磺酸基或磺酸根。取代基团包括‑H,‑X,‑OH,=O,‑C=OR,‑OR,‑COOR,‑CONHR,发色团,荧光团,空间分子,聚合物,低聚物,表面,或其结合。铝传感分子对铝离子具有强亲和力和强选择性。分析物铝离子物种包括自由的Al3+,或Al(OH)2+,Al(OH)2+,Al(OH)3,Al(OH)4‑,Al(III)配位化合物以及它们的混合物。分析媒介包含水溶液,溶剂,生物液及其混合物。此铝离子传感分子材料可以应用在颜色光谱、石英微天平、电极、电化学、表面等离子共振、局域表面等离子共振。
Description
技术领域
本发明涉及化学材料技术领域,特别是一种铝离子传感分子材料及其应用。
背景技术
铝是地壳中丰度最高的元素之一,其丰度接近硅元素。自然界中,铝矿主要存在形式为铝土矿,它包括三水铝矿Al(OH)3,软水铝石γ-AlO(OH),硬水铝石α-AlO(OH)。也有铝粘土高岭土Al2Si2O5(OH)。铝同位素主要以27Al存在,接近100%,其26Al同位素非常微量,但是26Al/10Be常用于无线电测年。铝金属与合金广泛用于交通、包装、建筑建造、电力、家用电器、机械与仪器。许多铝化合物被用在众多的用途中,包括以下这些:
1)氧化铝:磨砂、灯具、催化剂载体、干燥剂、吸收剂
2)硫酸铝:水处理、造纸、染料、种子浸洗、矿物油脱色、皮革鞣制
3)氯化铝:催化剂
4)氯化羟铝:水纯化、造纸、止汗剂
5)铝酸盐:水处理、水泥固化加速剂
6)醋酸铝:止血药
7)磷酸铝:玻璃、陶瓷、纸浆、化妆品、油漆、清漆、牙科水泥8)氢氧化铝:抗酸剂、染料、水纯化、玻璃、陶瓷、织物
9)四氢铝锂:有机合成还原剂
10)有机铝:路易斯酸、助催化剂
11)铝离子水溶液:处理鱼类寄生虫
12)有些铝盐:疫苗-免疫佐剂
至目前为止,没有发现铝具有生物学功能。小鼠的铝口服LD50为6207mg/kg。铝是非致癌物,但是过量的暴露或服用可能会导致疾病–软骨病、贫血、老年痴呆症、帕金森症、乳癌。人体主要吸收5种铝物种:
1)自由的溶剂化三价阳离子(Al3+(aq))
2)低分子量,电中性的,可溶化合物(LMW-Al0(aq))
3)高分子量,电中性的,可溶化合物(HMW-Al0(aq))
4)低分子量,带电荷的,可溶化合物(LMW-Al(L)n+/-(aq))
5)纳米与微米粒子(Al(L)n(s)).
环境铝源存在于采矿点、燃煤发电厂、以及焚烧炉。酸雨会转移天然铝源。工业生产流程是铝存在于盐和淡水的主要因素。铝对于鳃呼吸的动物(比如鱼类)有毒–引起血浆和血淋巴离子流失导致渗透压失调。有机铝干扰哺乳动物和鸟类新陈代谢。铝干扰植物根生长与功能从而减缓植物在酸性土壤中的生长。
为了防止铝污染环境以及水体,非常有必要定性于定量检测Al(III)含量。有许多现行的铝检测方法,包括原子吸收光谱(AAS)、诱导偶联等离子体原子发射光谱(ICP-AES)、和诱导偶联等离子体质谱(ICP-MS)。血清铝的检测采用离子对反向高效液相色谱-荧光检测器[1]。最近,科学家研究出水溶性的高选择性铝荧光传感器,采用萘酚醛-三羟甲基氨基甲烷衍生物检测铝离子[2]。另外一种水溶性的铝荧光传感器也被研究报道,原理基于聚集诱导发射增强[3]。Al(III)与水中4-丙氧磺酸水杨醛吖嗪(PSSA)配位引发了一个聚集诱导发射增强过程导致形成界限分明的树枝状结构,已经被几种分析技术表征(DLS、SEM、FLIM)。X.Leng等研发了一种基于罗丹明B的显色-荧光新探针,用于铝检测,在活细胞成像方面有应用[4]。柠檬酸根与聚乙烯吡咯烷酮稳定的银纳米粒子作为铝离子选择性比色传感器可应用于实际水样品[5]。两个吡啶衍生物席夫碱被合成并作为打开型荧光传感器用于铝离子检测[6]。
参考文献:
[1]Wu,J.;Zhou,C.Y.;Chi,H.;Wong,M.K.;Lee,H.K.;Ong,H.Y.;Ong,C.N.,DETERMINATION OF SERUM ALUMINUM USING AN ION-PAIR REVERSED-PHASE HIGH-PERFORMANCE LIQUID CHROMATOGRAPHIC-FLUOROMETRIC SYSTEM WITHLUMOGALLION.Journal of Chromatography B-Analytical Technologies in theBiomedical and Life Sciences 1995,663,(2),247-253.
[2]Liu,Z.C.;Li,Y.X.;Ding,Y.J.;Yang,Z.Y.;Wang,B.D.;Li,Y.;Li,T.R.;Luo,W.;Zhu,W.P.;Xie,J.P.;Wang,C.J.,Water-soluble and highly selective fluorescentsensor from naphthol aldehyde-tris derivate for aluminium iondetection.Sensors and Actuators B-Chemical 2014,197,200-205.
[3]Nguyen,H.L.;Kumar,N.;Audibert,J.F.;Ghasemi,R.;Lefevre,J.P.;Ha-Thi,M.H.;Mongin,C.;Leray,I.,Water-soluble aluminium fluorescent sensor based onaggregation-induced emission enhancement.New J.Chem.2019,43,(38),15302-15310.
[4]Leng,X.;Xu,W.F.;Qiao,C.F.;Jia,X.;Long,Y.;Yang,B.Q.,New rhodamineB-based chromo-fluorogenic probes for highly selective detection of aluminium(iii)ions and their application in living cell imaging.RSC Adv.2019,9,(11),6027-6034.
[5]del Portal-Vazquez,P.R.;Lopez-Perez,G.;Prado-Gotor,R.;Roman-Hidalgo,C.;Martin-Valero,M.J.,Citrate and Polyvinylpyrrolidone StabilizedSilver Nanoparticles as Selective Colorimetric Sensor for Aluminum(III)Ionsin Real Water Samples.Materials 2020,13,(6).
[6]Peng,H.N.;Han,Y.J.;Lin,N.;Liu,H.H.,Two pyridine-derived Schiff-bases as turn-on fluorescent sensor for detection of aluminiumion.Opt.Mater.2019,95.
发明内容
为解决现有技术中铝离子检测所存在的缺陷和问题,提供一种铝离子传感分子材料及其应用。
本发明为解决其技术问题所采用的技术方案是:本发明的一种铝离子传感分子材料简称为铝传感分子,其特征在于:所述的铝传感分子由基本单位和其上的四个取代基团组成;所述的基本单位由邻苯酚基苯磺酸或邻苯酚基苯磺酸根组成,在苯酚羟基邻位有一个磺酸基或磺酸根;
所述的铝传感分子上含四个取代基团,取代基团包括-H,-X,-OH,=O,-C=OR,-OR,-COOH,-COOR,-CHO,-NH2,-NHR,-NR2,-CONH2,-CONHR,-CONR2,-SO3H,-SO3M,-CH3,-CH2R,-CHR2,-CR3,-CR=CR2,-C≡CR,-SH,-SR,-N=NR,-C≡N,-CSNR2,-M,-NO2,发色团,荧光团,空间分子,聚合物,低聚物,表面,纳米粒子,或其结合;
所述的R代表-H或其他有机基团,所述的M和X分别代表金属与卤素;
所述的铝传感分子对铝离子物种具有强亲和力;
所述的铝传感分子对铝离子物种具有强选择性;
样品中如果有氟离子它会和铝离子结合形成铝氟配位化合物(AlFn)3-n(配位数n=1-6)形态存在,需加入Be2+离子破坏铝氟高配位化合物(n大于等于2)以释放自由铝离子Al3+和单配位的铝氟配位化合物AlF2+以便于被铝传感分子捕获检测;
所述的铝氟高配位化合物(AlFn)3-n(配位数n=2-6)形态在铝传感分子上信号微弱或无信号。
所述的四个取代基团,可以相同或不同。
所述的荧光团取代基团赋予铝传感分子荧光特性便于应用在荧光法、比色法、表面等离子共振法检测铝离子;所述的荧光团包括含有荧光基团的蛋白质,多肽,有机分子,低聚物,聚合物,及其结合。
所述的发色团取代基团赋予铝传感分子颜色特性取代基团赋予铝传感分子颜色特性便于应用在比色法、局域表面等离子共振法检测铝离子。
所述的空间分子用来根据需要给基本单位提高或降低移动灵活性;所述的空间分子包括烷烃、芳烃;烷烃类的空间分子一般可以提供基本单位移动灵活性;如果空间分子的物理点位在传感器的表面,其长度无需限制;如果空间分子的物理点位在孔内,必需把空间分子的长度限制在孔直径以内,最好是孔半径以内;在某些情况下(譬如选择性要求下)需要进行限制;可以给基本单位邻位附加一个或多个独立的或融合的芳环类或支链烷烃空间位阻分子形成萘环、蒽环或类似物作为大空间位阻取代基来限制其基本单位灵活性;基本单位上的四个取代基中两个相邻取代基联合成一个苯环的话,即与基本单位形成一个萘环。
所述的聚合物和表面使得铝传感分子以共价键形态强结合力结合于软、硬表面或以非共价键形态弱结合力附着于软、硬表面,便于应用在石英微天平、电极、电化学法进行铝离子检测。
所述的纳米粒子使得铝传感分子以共价键形态或非共价键形态附着于纳米粒子,便于应用在局域表面等离子共振方法进行铝离子检测。
所述的铝离子物种包括自由的Al3+,或Al(OH)2+,Al(OH)2+,Al(OH)3,Al(OH)4-,二聚体,多聚体,Al(III)配位化合物以及它们的混合物。
所述的氟离子广泛存在于样品中,饮用水中往往有添加氟离子使得人类牙齿坚固,许多环境样品中也含有相当高的氟离子含量;氟离子会和铝离子结合形成铝氟配位化合物(AlFn)3-n(配位数n=1-6)形态存在;需加入Be2+离子破坏铝氟高配位化合物(n等于2-6)以释放自由铝离子Al3+和单配位的铝氟配位化合物AlF2+以便于被铝传感分子捕获检测。
一种铝离子传感分子材料的应用,包括颜色光谱(荧光光谱,紫外可见光光谱),石英微天平,电极,电化学,表面等离子共振,以及局域表面等离子共振。
附图说明
下面结合附图和具体实施方式对本发明的一种铝离子传感分子材料及其应用作进一步说明。
图1是铝传感分子的分子结构示意图,其由基本单位-邻苯酚基苯磺酸或邻苯酚基苯磺酸根,与其上的四个取代基团R1、R2、R3、R4组成。
图2是铝传感分子的一些低分子量分子结构例子。
图3是铝传感分子的一些较高分子量分子结构例子。
图4是图3中铝传感分子14薄膜的照片,膜厚度约100nm,铝传感分子膜生长在石英晶体的金镀膜上,金膜直径6mm(左边)或12mm(右边)。
图5是铝离子Al(III)水溶液接触铝传感分子14薄膜的典型的频率随时间变化曲线,信号由石英微天平评价。
图6是200ppb Al(III)铝离子水溶液在铝传感分子14薄膜上的可重复性测试。相对标准偏差RSD±6.4%。信号由石英微天平评价。
图7是200ppb的各种离子水溶液在铝传感分子14薄膜上的选择性测试。信号由石英微天平评价。
图8是pH值4.46的不同浓度的Al(III)铝离子水溶液在铝传感分子14薄膜上的校正曲线。横坐标是log[Al]。信号由石英微天平评价。
图9是铝传感分子14薄膜的在线再生。
图10是含有0.45ppm氟离子以及许多基质和干扰物的自来水样品在铝传感分子14薄膜上的校正曲线。
图11是铝离子物种随pH值变化分布图。
具体实施方式:
如图1至图11所示,我们以石英微天平法为检测法来阐述应用铝离子传感分子的具体实施方式。
石英微天平传感晶片的一种制备法:
1.石英微天平传感晶片是圆形的石英晶体超薄片,直径14mm,其两面中心有圆形超薄镀金电极,圆形金电极直径6mm。石英晶片共振频率是10MHz。
2.清洁晶片:把晶片浸泡在新鲜Piranha溶液中(3体积浓硫酸+3体积30%双氧水)5分钟,取出用去离子水冲洗干净,用氮气吹干。
3.加强圆形金电极粘结性:为了使得铝传感分子薄膜与金电极结合更紧密,可以在金电极表面附着一个单分子层的3-巯基丙酸。用移液器取一定量的0.1%3-巯基丙酸溶液,置于圆形金电极表面均匀铺开,干燥。
4.制备晶片铝传感分子薄膜:用移液器取一定量的(1-10μL)0.1-1%wt.铝离子传感分子溶剂(比如二甲基亚砜)溶液,置于圆形金电极表面均匀铺开,干燥。
5.制备好的石英微天平传感晶片放入石英微天平流动池,根据石英微天平制造商的使用说明即可评价或使用。石英微天平(QCM-D)以及晶片是新加坡万事创新公司(MIPSInnovations Pte Ltd)制造。MIPS QCM-D的质量灵敏度是4.425ng·cm-2·Hz-1。MIPSQCM-D的共振频率变化灵敏度为1Hz,最小探测质量(绝对质量灵敏度)为0.40ng。评价参数可包括重复性、选择性、校正曲线、灵敏度、准确度、稳定性、抗干扰性,等等。
例1
图2展示了铝传感分子的一些低分子量分子结构例子。其中最小的结构是1,其上的取代基团都是H。分子2和3都含一个酚羟基-OH取代基。分子4和5含一个氯-Cl取代基或氨基-NH2取代基。分子6含一个羧基-COOH取代基。分子7含一个酚羟基-OH取代基和一个磺酸基-SO3H取代基。
例2
图3展示了铝传感分子的一些较高分子量分子结构例子。分子8是一个邻苯酚基苯磺酸含另外两个取代基–氯取代基和2-间苯二酚-偶氮取代基,此基团是一个荧光团,在500nm激发时,发射荧光范围在520–700nm之间。分子9是具有荧光团取代基的铝离子传感分子通用结构。分子10包含了一个空间分子,延长了邻苯酚基苯磺酸核心传感部分,使得传感分子更有弹性和移动性,适用于不同应用和不同的传感平台。空间分子可以包括任何分子,烷烃或芳烃,比如乙基,苯甲基,等。在某些特殊情况下,如果需要限制邻苯酚基苯磺酸核心传感部分的移动性,可以把邻苯酚基苯磺酸核心的苯环扩展成熔合的双环或多环,比如萘(在分子11中)、蒽或其他类似结构。邻苯酚基苯磺酸核心也可以连接聚合物(分子12),或者连接聚合物与空间分子(分子13、14)。当邻苯酚基苯磺酸核心被嫁接或吸附到一个表面时,核心与表面之间可以有空间分子(分子15、16),核心与表面之间可以有聚合物与空间分子(分子17)。
例3
在石英微天平(制造商:新加坡万事创新公司制造(MIPS Innovations Pte Ltd))的镀金石英晶片的圆形金电极上,镀上一层铝传感分子14(图3)薄膜,约100nm厚。图4展示了图3中铝传感分子14的薄膜照片,膜厚度约100nm,铝传感分子膜生长在石英晶体的金镀膜上,金膜直径6mm(左边)或12mm(右边)。图5展示了铝离子Al(III)水溶液接触铝传感分子14薄膜的典型的频率随时间变化曲线。随着铝离子在传感分子14薄膜上吸附得越来越多,石英晶片的共振频率变小。一次测试后,铝传感分子可以用酸和/或碱快速再生。再生后,用去离子水走基线稳定后可以开始第二次测试。14图6展示了200ppb Al(III)铝离子水溶液在铝传感分子14薄膜上的可重复性测试。相对标准偏差RSD±6.4%。说明了铝传感分子14薄膜测试铝离子重复性很好。图7展示了200ppb的各种离子水溶液在铝传感分子14薄膜上的选择性测试。铝传感分子14薄膜对铝离子表现出了很高的选择性,Cu(II),Cd(II),Cr(III),Na(I),Fe(III)和Co(II)离子在其上有少许信号,其他离子Zn(II),Ni(II),Mg(II),Ca(II),K(I),Pb(II),Cr(VI),As(III),As(V),Hg(II),Fe(II),Ag(I),以及Mn(II)离子在其上基本无信号(图7)。
表1铝传感分子14薄膜对不同pH值条件下的10ppb的铝离子的频率变化信号ΔF(Hz)
表2铝传感分子14薄膜对不同pH值条件下的100ppb的铝离子的频率变化信号ΔF(Hz)
铝传感分子14薄膜对不同pH值敏感。正如表1所示,在pH值为4.46时,浓度10ppb的铝离子Al(III)溶液在铝传感分子14薄膜上引起的频率变化信号ΔF达到最大值。图11展示了铝离子物种随pH值变化分布图。铝离子物种包括自由的Al3+,或Al(OH)2+,Al(OH)2+,Al(OH)3,Al(OH)4-,二聚体,多聚体,Al(III)配位化合物以及它们的混合物。pH值工作范围是4.0–4.8,在此pH范围铝离子Al(III)主要以自由铝离子Al3+存在,还有少量的氢氧化铝Al(OH)2+and Al(OH)2+离子。在pH值为4.60时,浓度100ppb的铝离子Al(III)溶液在铝传感分子14薄膜上引起的频率变化信号ΔF达到最大值(表2).
表3用pH值4.46的不同浓度的铝离子溶液校正铝传感分子14薄膜引起的频率变化信号
[Al](ppb) | CorrectedΔF in 5'(Hz) |
0 | 0 |
10 | 53.9 |
20 | 89.4 |
50 | 119.7 |
100 | 133.8 |
200 | 145.2 |
表3列举了用pH值4.46的不同浓度的铝离子溶液校正铝传感分子14薄膜引起的频率变化信号。表3的数据作图,在图8中展示了pH值4.46的不同浓度的Al(III)铝离子水溶液在铝传感分子14薄膜上的校正曲线,横坐标是log[Al]。其校正曲线具有良好线性,R20.9548接近1。计算出的最低检测限(LOD)是1.0ppb,非常低,意味着铝传感分子14薄膜具有很高灵敏度。
图9展示了铝传感分子14薄膜的在线再生。如图9所示,铝传感分子14薄膜一次测试后,可以用酸和/或碱快速再生。再生后,用去离子水走基线稳定后可以开始第二次测试。测试后,铝离子或其他金属离子可以用10mM NaOH在线清除,然后再用10mM硝酸在线清洗以让铝传感分子14薄膜重新质子化,之后再用去离子水清洗掉酸残余并让铝传感分子14薄膜基线平直。
氟离子广泛存在于样品中,饮用水中往往有添加氟离子使得人类牙齿坚固。样品中如果有氟离子它会和铝离子结合形成铝氟配位化合物(AlFn)3-n(配位数n=1-6)形态存在。许多环境(水体、土壤、空气)样品中也含有相当高的氟离子含量。因此铝氟配位化合物AlFn3-n(n=1-6)也广泛存在于环境样品中。当n大于等于2,铝氟配位化合物AlFn3-n(n=1-6)在铝传感分子14薄膜上无信号。因此,本申请的其中一个创新点是,加入Be2+离子破坏铝氟高配位化合物(n≧2)以释放自由铝离子Al3+和单配位的铝氟配位化合物AlF2+以便于被铝传感分子捕获检测。自由铝离子Al3+和单配位的铝氟配位化合物AlF2+在铝传感分子14薄膜上皆有良好信号。图10展示了含有0.45ppm以及富含基质和干扰物的自来水样品在铝传感分子14薄膜上的校正曲线。证明了铝传感分子14薄膜能够检测含氟样品中的铝离子。同时也证明了铝传感分子14薄膜能够用于检测含有许多基质和干扰物的实际样品,而不仅仅是实验室用去离子水配出来的无基质无干扰的样品。
根据本发明的实施例已对本发明进行了说明性而非限制性的描述,但应理解,本发明的保护范围并不局限于此,在不脱离由权利要求所限定的相关保护范围的情况下,本领域的技术人员可以做出变更和/或修改,在此基础之上的任何修改、等同替换等,都应涵盖在本发明的保护范围之内。
Claims (10)
1.一种铝离子传感分子材料,简称为铝传感分子,其特征在于:所述的铝传感分子由基本单位和其上的四个取代基团组成;所述的基本单位由邻苯酚基苯磺酸或邻苯酚基苯磺酸根组成,在苯酚羟基邻位有一个磺酸基或磺酸根;
所述的铝传感分子上含四个取代基团,取代基团包括-H,-X,-OH,=O,-C=OR,-OR,-COOH,-COOR,-CHO,-NH2,-NHR,-NR2,-CONH2,-CONHR,-CONR2,-SO3H,-SO3M,-CH3,-CH2R,-CHR2,-CR3,-CR=CR2,-C≡CR,-SH,-SR,-N=NR,-C≡N,-CSNR2,-M,-NO2,发色团,荧光团,空间分子,聚合物,低聚物,表面,纳米粒子,或其结合;
所述的R代表-H或其他有机基团,所述的M和X分别代表金属与卤素;
所述的铝传感分子对铝离子物种具有强亲和力;
所述的铝传感分子对铝离子物种具有强选择性;
样品中如果有氟离子它会和铝离子结合形成铝氟配位化合物(AlFn)3-n(配位数n=1-6)形态存在,需加入Be2+离子破坏铝氟高配位化合物(n大于等于2)以释放自由铝离子Al3+和单配位的铝氟配位化合物AlF2+以便于被铝传感分子捕获检测;
所述的铝氟高配位化合物(AlFn)3-n(配位数n=2-6)形态在铝传感分子上信号微弱或无信号。
2.根据权利要求1所述的一种铝离子传感分子材料,其特征在于:所述的四个取代基团,可以相同或不同。
3.根据权利要求1所述的一种铝离子传感分子材料,其特征在于:所述的荧光团取代基团赋予铝传感分子荧光特性便于应用在荧光法、比色法、表面等离子共振法检测铝离子;所述的荧光团包括含有荧光基团的蛋白质,多肽,有机分子,低聚物,聚合物,及其结合。
4.根据权利要求1所述的一种铝离子传感分子材料,其特征在于:所述的发色团取代基团赋予铝传感分子颜色特性取代基团赋予铝传感分子颜色特性便于应用在比色法、局域表面等离子共振法检测铝离子。
5.根据权利要求1所述的一种铝离子传感分子材料,其特征在于:所述的空间分子用来根据需要给基本单位提高或降低移动灵活性;所述的空间分子包括烷烃、芳烃;烷烃类的空间分子一般可以提供基本单位移动灵活性;如果空间分子的物理点位在传感器的表面,其长度无需限制;如果空间分子的物理点位在孔内,必需把空间分子的长度限制在孔直径以内,最好是孔半径以内;在某些情况下(譬如选择性要求下)需要进行限制;可以给基本单位邻位附加一个或多个独立的或融合的芳环类或支链烷烃空间位阻分子形成萘环、蒽环或类似物作为大空间位阻取代基来限制其基本单位灵活性;基本单位上的四个取代基中两个相邻取代基联合成一个苯环的话,即与基本单位形成一个萘环。
6.根据权利要求1所述的一种铝离子传感分子材料,其特征在于:所述的聚合物和表面使得铝传感分子以共价键形态强结合力结合于软、硬表面或以非共价键形态弱结合力附着于软、硬表面,便于应用在石英微天平、电极、电化学法进行铝离子检测。
7.根据权利要求1所述的一种铝离子传感分子材料,其特征在于:所述的纳米粒子使得铝传感分子以共价键形态或非共价键形态附着于纳米粒子,便于应用在局域表面等离子共振方法进行铝离子检测。
8.根据权利要求1所述的一种铝离子传感分子材料,其特征在于:所述的铝离子物种包括自由的Al3+,或Al(OH)2+,Al(OH)2+,Al(OH)3,Al(OH)4-,二聚体,多聚体,Al(III)配位化合物以及它们的混合物。
9.根据权利要求1所述的一种铝离子传感分子材料,其特征在于:所述的氟离子广泛存在于样品中,饮用水中往往有添加氟离子使得人类牙齿坚固,许多环境样品中也含有相当高的氟离子含量;氟离子会和铝离子结合形成铝氟配位化合物(AlFn)3-n(配位数n=1-6)形态存在;需加入Be2+离子破坏铝氟高配位化合物(n等于2-6)以释放自由铝离子Al3+和单配位的铝氟配位化合物AlF2+以便于被铝传感分子捕获检测。
10.根据权利要求1所述的一种铝离子传感分子材料的应用,包括颜色光谱(荧光光谱,紫外可见光光谱),石英微天平,电极,电化学,表面等离子共振,以及局域表面等离子共振。
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