CN114222754A - A型肉毒杆菌毒素复合物、其配制剂和使用方法 - Google Patents

A型肉毒杆菌毒素复合物、其配制剂和使用方法 Download PDF

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CN114222754A
CN114222754A CN202080028618.2A CN202080028618A CN114222754A CN 114222754 A CN114222754 A CN 114222754A CN 202080028618 A CN202080028618 A CN 202080028618A CN 114222754 A CN114222754 A CN 114222754A
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botulinum toxin
toxin type
complex
component
seq
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曹子文
王永凯
沈冠成
吴岳缙
游丞德
曾毓俊
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OBI Pharma Inc
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Abstract

本发明涉及A型肉毒杆菌毒素复合物、其配制剂和使用方法。本发明提供了一种A型肉毒杆菌毒素复合物,其包含HA70组分、HA17组分、HA33组分、NTNH组分和BoNT/A1组分,其中所述肉毒杆菌毒素复合物具有740‑790kDa的分子量。与现有的肉毒杆菌毒素复合物相比,本发明的肉毒杆菌毒素复合物的分子量更小,安全性更高,且具有相当的治疗效果。

Description

PCT国内申请,说明书已公开。

Claims (21)

  1. PCT国内申请,权利要求书已公开。
CN202080028618.2A 2020-03-31 2020-03-31 A型肉毒杆菌毒素复合物、其配制剂和使用方法 Pending CN114222754A (zh)

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US (1) US20220257730A1 (zh)
EP (1) EP3932938A4 (zh)
JP (1) JP7328714B2 (zh)
KR (2) KR20220003061A (zh)
CN (2) CN114222754A (zh)
AU (1) AU2020440362B2 (zh)
BR (1) BR112021024058A2 (zh)
MX (1) MX2021014486A (zh)
NZ (1) NZ780855A (zh)
SA (1) SA521430958B1 (zh)
SG (1) SG11202111282SA (zh)
WO (1) WO2021195968A1 (zh)

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WO2005035730A2 (en) * 2003-10-07 2005-04-21 Allergan, Inc. Dna sequences of the botulinum neurotoxin complex of type a-hall (allergan) strain
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NZ780855A (en) 2023-06-30
BR112021024058A2 (pt) 2022-10-11
US20220257730A1 (en) 2022-08-18
MX2021014486A (es) 2022-01-04
SA521430958B1 (ar) 2024-02-22
AU2020440362B2 (en) 2023-02-16
SG11202111282SA (en) 2021-11-29
CN116041452A (zh) 2023-05-02
EP3932938A1 (en) 2022-01-05
WO2021195968A1 (zh) 2021-10-07
KR20220003061A (ko) 2022-01-07
KR20230146125A (ko) 2023-10-18
JP7328714B2 (ja) 2023-08-17
AU2020440362A1 (en) 2021-11-04
EP3932938A4 (en) 2022-11-30

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