CN114217060B - Virus detection device for improving detection safety - Google Patents

Virus detection device for improving detection safety Download PDF

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Publication number
CN114217060B
CN114217060B CN202111459462.6A CN202111459462A CN114217060B CN 114217060 B CN114217060 B CN 114217060B CN 202111459462 A CN202111459462 A CN 202111459462A CN 114217060 B CN114217060 B CN 114217060B
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detection
groove
driving
virus
reagent tube
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CN114217060A (en
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马力敏
曾文涛
路明
范珈豪
覃炎兰
汪洋
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Shenzhen Zijian Biotech Co ltd
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Shenzhen Zijian Biotech Co ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56983Viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/18Liquid substances or solutions comprising solids or dissolved gases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/26Accessories or devices or components used for biocidal treatment
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/5302Apparatus specially adapted for immunological test procedures
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178Special arrangements of analysers
    • G01N2035/00277Special precautions to avoid contamination (e.g. enclosures, glove- boxes, sealed sample carriers, disposal of contaminated material)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N2035/00178Special arrangements of analysers
    • G01N2035/00306Housings, cabinets, control panels (details)
    • G01N2035/00316Detecting door closure
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Health & Medical Sciences (AREA)
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Abstract

The utility model relates to a virus detection device for improving detection safety, it includes the detection case and is used for depositing the reagent pipe of virus reagent, be provided with sealed lid on the reagent pipe, the slip is provided with the detection platform in the detection case, be provided with the clamping mechanism who is used for fixed reagent pipe on the detection platform, be provided with the first driving piece that is used for driving the detection platform to slide in the detection case, set up the inlet that is used for supplying the detection platform to roll off on the detection case, be provided with the closing plate that is used for sealing the inlet on the detection case; the detection box is internally provided with a cover opening assembly for opening or closing a sealing cover on the reagent tube and a detection assembly for detecting virus reagents. The method has the effect of high safety during virus detection.

Description

Virus detection device for improving detection safety
Technical Field
The present application relates to the field of detection devices, and in particular, to a virus detection device for improving detection security.
Background
The virus is a non-cellular life form, and is composed of a nucleic acid long chain and a protein shell, and the virus has no own metabolic mechanism and no enzyme system; thus, the virus leaves the host cell and becomes a chemical that does not have any vital activity and is unable to self-propagate independently; its ability to replicate, transcribe, and translate is performed in a host cell, and when it enters the host cell, it can use the substances and energy in the cell to complete life activities, producing a new generation virus as it is according to the genetic information contained in its own nucleic acid.
Currently, in detecting viruses, an early diagnosis of virus infection is usually performed by using an immunolabeling technique, i.e., labeling antibodies such as fluorescein, radionuclide, peroxidase, etc., and observing the antibodies with a microscope to detect antigens in a specimen.
The related art in the above has the following drawbacks: viruses generally have strong fluidity and adhesiveness, and when a virus reagent is detected, part of the viruses easily flow through air and adhere to clothes of a detector or directly enter the detector through the respiratory tract, so that great potential safety hazards are caused to the detector.
Disclosure of Invention
For safety in virus detection, the present application provides a virus detection device for improving detection safety.
The application provides a virus detection device for improving detection security adopts following technical scheme:
the utility model provides a virus detection device for improving detection security, includes detection case and is used for depositing the reagent pipe of virus reagent, be provided with sealed lid on the reagent pipe, the detection incasement slides and is provided with the detection platform, be provided with the clamping mechanism who is used for fixed reagent pipe on the detection platform, be provided with the first driving piece that is used for driving the detection platform to slide in the detection case, set up the business turn over mouth that is used for supplying the detection platform to roll out on the detection case, be provided with the closing plate that is used for sealing the business turn over mouth on the detection case; the detection box is internally provided with a cover opening assembly for opening or closing a sealing cover on the reagent tube and a detection assembly for detecting virus reagents.
By adopting the technical scheme, the extracted virus reagent is stored in the reagent tube and is sealed by the sealing cover; when viruses are detected, a reagent tube filled with the viruses is placed on a detection table, the reagent tube is fixed through a clamping mechanism, then the detection table is driven to slide through a first driving piece and enters a detection box, and a box inlet of the detection box is sealed through a sealing plate; the cover opening assembly is used for opening a sealing cover on the reagent tube, and the detection assembly is used for detecting viruses; in the detection process, viruses are not easy to flow along with air, and are attached to clothes of detection personnel or directly enter the detection personnel through respiratory tract, so that the safety of virus detection is high.
Optionally, the standing groove that is used for placing the reagent pipe has been seted up on the detection platform, clamping mechanism includes clamp splice and drive assembly, the clamp splice is provided with two, two holding grooves with the standing groove intercommunication have been seted up to the lateral wall of standing groove, two the clamp splice slides respectively and sets up in two holding grooves, drive assembly is used for driving two clamp splice and is close to or keep away from each other.
Through adopting above-mentioned technical scheme, place the reagent pipe in the standing groove of detecting the platform, drive two clamp splice mutual approaching or keeping away from through drive assembly to the realization is fixed to reagent pipe's clamp.
Optionally, two ends of the clamping blocks, which are close to each other, are provided with anti-slip pads, and the anti-slip pads are made of elastic materials.
Through adopting above-mentioned technical scheme, two clamp splice are carrying out clamp fastening to the reagent pipe and are being fixed time, contact through slipmat and reagent pipe, increase the stability when pressing from both sides tight to actual pipe to, owing to slipmat adopts elastic material, can also prevent to a certain extent that two clamp splice from being too big because of the clamp force, make the reagent pipe break.
Optionally, the drive assembly includes adjusting screw and driving medium, two all rotate in the storage tank and be provided with adjusting screw, threaded hole has been seted up along the slip direction of clamp splice to the one end that is close to the storage tank bottom wall on the clamp splice, adjusting screw wears to locate the screw hole and with clamp splice threaded connection, the driving medium is used for driving two adjusting screw and rotates simultaneously.
By adopting the technical scheme, the two adjusting screws are driven to rotate simultaneously through the transmission piece, and the two adjusting screws are connected with the clamping blocks through threads and respectively drive the two clamping blocks to slide in the accommodating groove when rotating, so that the two clamping blocks are driven to be close to or far away from each other; and when the adjusting screw stops rotating, the clamping blocks can be limited, and the chain clamping blocks are placed to be loose to a certain extent.
Optionally, the driving medium includes the rack, two the first spread groove has been seted up along the slip direction of perpendicular clamp splice to the lateral wall of holding tank, all slide in the first spread groove and be provided with the rack, two all coaxial fixed being provided with the gear on the adjusting screw, just rack and gear engagement, the second spread groove with the standing groove intercommunication has been seted up along the slip direction of rack to the lateral wall of first spread groove, slide along the slip direction of rack in the standing groove and be provided with the briquetting, two rack and briquetting fixed connection, be provided with in the standing groove and be used for driving the gliding first top of briquetting.
By adopting the technical scheme, when the reagent tube is placed in the placing groove, the bottom end of the reagent tube is abutted against the surface of the pressing block, the reagent tube is continuously pressed down, the pressing block is pushed by the reagent tube to slide towards the direction close to the wall of the placing groove, and the two racks are driven to slide in the first connecting groove respectively; when the reagent tube needs to be taken down, the first pushing piece drives the pressing block to be far away from the bottom wall of the placing groove, and drives the two adjusting screws to reversely rotate, so that the two clamping blocks are far away from each other, and the reagent tube can be taken down.
Optionally, the first pushing component comprises a spring, the spring is arranged in the placing groove, one end of the spring is abutted with the bottom wall of the placing groove, the other end of the spring is abutted with the pressing block, and a limiting component for limiting the sliding of the pressing block is arranged in the placing groove.
By adopting the technical scheme, when the reagent tube is placed in the placing groove and the pressing block is pushed to slide towards the direction close to the bottom wall of the placing groove, the spring is pressed, and after the two clamping blocks clamp and fix the reagent tube, the pressing block is limited to slide by the limiting piece; when the reagent tube needs to be taken down, the pressing block slides towards the direction away from the bottom wall of the placing groove under the action of the elasticity of the spring only by loosening the limiting piece, so that the two clamping blocks are mutually away from each other, and the reagent tube can be taken down.
Optionally, the locating part includes the stopper, the spacing groove has been seted up along the slip direction of perpendicular briquetting to the lateral wall of briquetting, the stopper slides and sets up in the spacing inslot, be provided with in the spacing groove and be used for driving the stopper to keeping away from the gliding elastic component of spacing tank bottom wall direction, the draw-in groove that is used for supplying stopper male is seted up to the lateral wall of standing groove, be provided with on the detection platform and be used for ejecting the second of draw-in groove with the stopper and push away the piece.
By adopting the technical scheme, the limiting block is always positioned in the limiting groove in the process that the pressing block slides towards the direction close to the bottom wall of the placing groove, when the two clamping blocks clamp the reagent tube, the limiting block is opposite to the clamping groove, and the limiting block is inserted into the clamping groove under the elastic action of the elastic piece, so that the limiting block is limited; when the reagent tube needs to be taken down, the limiting block is ejected out of the clamping groove through the second pushing piece, and the pressing block can slide in the placing groove.
Optionally, uncapping the subassembly and including adapter sleeve, second driving piece and third driving piece, the direction slip along parallel detection case diapire in the detection case is provided with the mounting panel, the second driving piece is used for driving the mounting panel to slide, the adapter sleeve slides along the direction of perpendicular mounting panel and sets up on the mounting panel, the third driving piece sets up on the mounting panel, just the third driving piece is used for driving the adapter sleeve to slide, fixedly on the adapter sleeve be provided with the spliced block, sealed lid lock joint is on the reagent pipe, set up on the sealed lid and be used for supplying spliced block male spliced groove.
Through adopting above-mentioned technical scheme, the reagent pipe is after getting into the detection case, and it slides to drive the mounting panel case to be close to reagent pipe direction through the second driving piece to make the grafting piece on the adapter sleeve insert the spliced groove on the sealed lid, afterwards, drive the adapter sleeve through the third driving piece and upwards slide, can make sealed lid and reagent pipe break away from, the mounting panel is kept away from to the rethread second driving piece, can detect the viral reagent in the reagent pipe.
Optionally, the detection component comprises a syringe and a microscope, wherein the syringe is fixedly arranged on the detection box, the syringe is internally used for storing the reaction reagent, the syringe is communicated with an injection needle, the injection needle is fixedly arranged in the detection box, and the microscope is fixedly arranged on the top wall of the detection box.
By adopting the technical scheme, the reagent tube is firstly slipped to the right position of the injection needle, the reaction reagent is injected into the reagent tube through the liquid guide tube and the injection needle by the injector, and then the reagent tube is slipped to the observation position of the microscope, so that the virus can be detected.
Optionally, the fixed liquid storage pot that is provided with on the detection case, the antiseptic solution has been deposited to the liquid storage pot, the intercommunication has the shower nozzle on the liquid storage pot, the shower nozzle extends to the detection incasement, be provided with the water pump that is used for carrying the antiseptic solution to the shower nozzle on the liquid storage pot.
Through adopting above-mentioned technical scheme, after the virus detects, carry the antiseptic solution in the liquid storage pot to the shower nozzle through the water pump to spray the antiseptic solution at the detection incasement, disinfect the surface of detecting incasement portion and reagent pipe and detection platform, further improve the security.
In summary, the present application includes at least one of the following beneficial technical effects:
1. when viruses are detected, a reagent tube filled with the viruses is placed on a detection table, the reagent tube is fixed through a clamping mechanism, then the detection table is driven to slide through a first driving piece and enters a detection box, and a box inlet of the detection box is sealed through a sealing plate; the cover opening assembly is used for opening a sealing cover on the reagent tube, and the detection assembly is used for detecting viruses; in the detection process, viruses are not easy to flow along with air, and are attached to clothes of detection personnel or directly enter the detection personnel through respiratory tract, so that the safety of virus detection is high;
2. when the reagent tube is placed in the placing groove, the bottom end of the reagent tube is abutted against the surface of the pressing block, the reagent tube is continuously pressed down, the pressing block is pushed by the reagent tube to slide towards the direction close to the wall of the placing groove, and the two racks are driven to slide in the first connecting groove respectively;
3. after virus detection is completed, the disinfectant in the liquid storage tank is conveyed to the spray head through the water pump, and is sprayed in the detection box, so that the inside of the detection box and the surfaces of the reagent tube and the detection table are disinfected, and the safety is further improved.
Drawings
FIG. 1 is a schematic overall structure of an embodiment of the present application;
FIG. 2 is a cross-sectional view of an embodiment of the present application, primarily for expressing the mounting relationship of the seal plate to the test case, and the specific construction of the door assembly and test assembly;
FIG. 3 is an enlarged view of portion A of FIG. 2;
FIG. 4 is an enlarged view of portion B of FIG. 2;
FIG. 5 is a cross-sectional view of an embodiment of the present application, primarily for expressing the mounting relationship of the reservoir tank to the test tank, and the internal structure of the test stand;
FIG. 6 is an enlarged view of portion C of FIG. 5;
fig. 7 is a partial structural sectional view of an embodiment of the present application, mainly for expressing the internal structure of the inspection station.
Reference numerals illustrate: 1. a detection box; 11. a first driving member; 111. a support plate; 12. a box inlet; 121. a sealing plate; 13. sealing grooves; 131. a sealing gasket; 14. a fixing plate; 15. a guide groove; 151. a pull rod; 152. a pull rope; 153. a first tension spring; 16. a mounting plate; 17. a liquid storage tank; 171. a water pump; 172. a water conduit; 173. a spray head; 2. a reagent tube; 21. sealing cover; 211. a plug section; 212. a connection section; 2121. a plug-in groove; 3. a detection table; 31. a placement groove; 311. a clamping groove; 32. a receiving groove; 33. a first connection groove; 34. a second connecting groove; 341. a connecting rod; 35. briquetting; 351. a rubber pad; 352. a limit groove; 353. an elastic member; 36. a spring; 37. a limiting block; 38. a push rod; 381. an anti-falling block; 382. a second tension spring; 39. a through hole; 4. a cover opening assembly; 41. connecting sleeves; 411. a plug block; 42. a second driving member; 43. a third driving member; 5. a detection assembly; 51. a syringe; 511. a catheter; 512. an injection needle; 52. a microscope; 6. a clamping mechanism; 61. clamping blocks; 611. an anti-slip pad; 62. a drive assembly; 621. adjusting a screw; 6211. a gear; 622. a rack.
Detailed Description
The present application is described in further detail below in conjunction with figures 1-7.
The embodiment of the application discloses a virus detection device for improving detection safety. Referring to fig. 1, the kit comprises a detection box 1 and a reagent tube 2 for storing virus reagents, wherein a sealing cover 21 is fastened on the reagent tube 2, the top wall and the side wall of the detection box 1 are both provided with observation windows, the observation windows are sealed by glass plates, a detection table 3 is arranged in the detection box 1 in a sliding manner, a first driving piece 11 for driving the detection table 3 to slide is arranged in the detection box 1, and a placing groove 31 for placing the reagent tube 2 is formed in the top end of the detection table 3 along the direction of a vertical supporting plate 111; the side wall of the detection box 1 is provided with a box inlet 12 for the detection table 3 to slide out, and the detection box 1 is provided with a sealing cover 21 for sealing the box inlet 12; the detection box 1 is internally provided with a cover opening assembly 4 for opening a sealing cover 21 on the reagent tube 2 and a detection assembly 5 for detecting virus reagents.
Referring to fig. 1, the first driving member 11 includes first rodless cylinders, two first rodless cylinders are provided, the extent directions of the two first rodless cylinders are parallel, the length directions of the two first rodless cylinders are perpendicular to the side wall of the detection box 1, which is provided with the box inlet 12, the piston rods of the two first rodless cylinders are welded together with the support plate 111, and the detection table 3 is fixedly arranged on the support plate 111.
Referring to fig. 2 and 3, the sealing plate 121 is hinged at the box inlet 12 of the detection box 1, the side wall of the detection box 1 is provided with a sealing groove 13 communicated with the box inlet 12, the sealing groove 13 is used for inserting the sealing plate 121, the bottom wall of the sealing groove 13 is adhered with a sealing gasket 131, the sealing gasket 131 is made of rubber, after the detection table 3 enters the detection box 1, the sealing plate 121 is rotated to enable the sealing plate 121 to be abutted against the sealing gasket 131, so that the detection box 1 is sealed, a closed space is formed in the detection box 1, and the safety during virus detection is greatly improved.
Referring to fig. 3, a fixing plate 14 is fixedly arranged in the detection box 1, two guide grooves 15 communicated with the sealing groove 13 are formed in the bottom wall of the sealing groove 13 along the sliding direction of the detection table 3, the two guide grooves 15 are respectively arranged on two sides of the sealing plate 121, the guide grooves 15 extend into the fixing plate 14, a pull rod 151 is slidably arranged in the guide grooves 15, a pull rope 152 is fixedly arranged on the pull rod 151, the pull rope 152 is fixedly connected with the sealing plate 121, a first tension spring 153 is arranged in the guide grooves 15, one end of the first tension spring 153 is fixedly connected with the bottom wall of the guide groove 15, and the other end of the first tension spring 153 is fixedly connected with the pull rod 151.
When the detection table 3 slides out of the detection box 1, the support plate 111 is abutted against one end of the sealing plate 121, which is close to the inside of the detection box 1, and the support plate 111 is continuously driven to slide, and the support plate 111 pushes the sealing plate 121 to rotate, so that the sealing plate 121 can be opened; when the detection table 3 slides into the detection box 1, the supporting plate 111 loses the abutting force to the sealing plate 121, at the moment, the first tension spring 153 pulls the pull rod 151 to slide towards the direction close to the bottom wall of the guide groove 15, and the pull rope 152 drives the sealing plate 121 to rotate, so that the box inlet 12 is sealed with the sealing plate 121, the whole process is free from manual operation, and convenience in use is greatly improved.
Referring to fig. 2 and 4, the cover opening assembly 4 includes a connecting sleeve 41, a second driving member 42 and a third driving member 43, a mounting plate 16 is slidably disposed in the detection box 1 along a sliding direction of the support plate 111, the second driving member 42 includes two second rodless cylinders, the two second rodless cylinders are fixedly disposed on two sidewalls of the detection box 1, a length direction of the second rodless cylinders is parallel to the sliding direction of the mounting plate 16, and the mounting plate 16 is welded with a piston of the second rodless cylinder.
Referring to fig. 2 and 4, the connecting sleeve 41 is slidably disposed at the bottom of the mounting plate 16 along the direction perpendicular to the mounting plate 16, the third driving member 43 includes a driving cylinder fixedly disposed at the top wall of the mounting plate 16, a piston rod of the driving cylinder penetrates through the mounting plate 16 and is fixedly connected with the connecting sleeve 41, and an insertion block 411 is fixedly disposed on the inner wall of the connecting sleeve 41; the sealing cover 21 is integrally formed with the connecting section 211 and 212, the connecting section 211 and the connecting section 212 are made of rubber, the connecting end is used for being inserted into the reagent tube 2, the side wall of the connecting section 212 is provided with a connecting groove 2121 for the inserting of the connecting block 411, and the connecting groove 2121 is circumferentially arranged on the side wall of the connecting section 212.
After the reagent tube 2 enters the detection box 1, the second rodless cylinder drives the mounting plate 16 box to slide in the direction close to the reagent tube 2, the plug 411 on the connecting sleeve 41 is inserted into the plug groove 2121 on the sealing cover 21, then the driving cylinder drives the connecting sleeve 41 to slide upwards, the sealing cover 21 can be separated from the reagent tube 2, the second driving piece 42 drives the mounting plate 16 to be far away from the reagent tube 2, and the virus reagent in the reagent tube 2 can be detected.
Referring to fig. 2 and 4, the detection assembly 5 comprises a syringe 51 and a microscope 52, the syringe 51 is fixedly arranged on the side wall of the detection box 1, the outlet end of the syringe 51 is communicated with a liquid guide tube 511, the liquid guide tube 511 extends into the detection box 1, the liquid guide tube 511 is communicated with an injection needle 512, the reagent tube 2 slides to the right position of the injection needle 512, and the syringe 51 is used for storing reaction reagents such as fluorescein, radionuclide, peroxidase and the like; the microscope 52 is fixedly arranged on the top wall of the detection box 1; the reagent tube 2 is slid to the position opposite to the injection needle 512, the reaction reagent is injected into the reagent tube 2 through the catheter 511 and the injection needle 512 by the syringe 51, and then the reagent tube 2 is slid to the observation position of the microscope 52, thereby detecting the virus.
Referring to fig. 5, a liquid storage tank 17 is fixedly arranged on the side wall of the detection box 1, a water inlet is formed in the top wall of the liquid storage tank 17, an end cover is fastened at the water inlet, disinfectant is stored in the liquid storage tank 17, and the disinfectant is usually alcohol, so that different disinfectant can be arranged according to the characteristics of actually detected viruses in actual use; the diapire of liquid storage jar 17 has seted up the delivery port, and the delivery port is provided with water pump 171, and the delivery port of liquid storage jar 17 and the water inlet end intercommunication of water pump 171, and the outlet pipe intercommunication of water pump 171 has aqueduct 172, and aqueduct 172 extends to in the detection case 1, and the one end intercommunication that aqueduct 172 is located detection case 1 has shower nozzle 173, and shower nozzle 173 is close to the top of detection case 1.
After virus detection is completed, the sealing cover 21 is buckled back to the reagent tube 2 through the cooperation of the second rodless cylinder and the driving cylinder, and then the disinfectant in the liquid storage tank 17 is conveyed to the spray head 173 through the water pump 171 and sprayed into the detection box 1, so that the inside of the detection box 1 and the surfaces of the reagent tube 2 and the detection table 3 are disinfected, and the safety is further improved.
Referring to fig. 6, a clamping mechanism 6 for fixing the reagent tube 2 is provided on the detection table 3, the clamping mechanism 6 includes a clamping block 61 and a driving component 62, two accommodating grooves 32 are provided on the side wall of the accommodating groove 31 along the direction parallel to the supporting plate 111, two clamping blocks 61 are provided, the two clamping blocks 61 are respectively slidably provided in the two accommodating grooves 32, the two clamping blocks 61 are symmetrically provided along the central axis of the accommodating groove 31, and the driving component 62 is used for driving the two clamping blocks 61 to approach or separate from each other; the reagent tube 2 is placed in the placing groove 31 of the detection table 3, and the two clamping blocks 61 are driven to be close to or far away from each other by the driving component 62, so that the reagent tube 2 is clamped and fixed.
Referring to fig. 6, the two clamping blocks 61 are adhered with anti-slip pads 611 at the ends close to each other, the anti-slip pads 611 are made of elastic materials, and in this application, the anti-slip pads 611 are made of rubber materials; in other embodiments, the skid pad 611 may be replaced with a sponge; when the reagent tube 2 is clamped and fastened by the two clamping blocks 61, the anti-slip pad 611 is in contact with the reagent tube 2, so that the stability of the actual tube during clamping is improved, and the anti-slip pad 611 is made of an elastic material, so that the reagent tube 2 can be prevented from being broken due to overlarge clamping force of the two clamping blocks 61 to a certain extent.
Referring to fig. 6, the driving assembly 62 includes two adjusting screws 621 and a driving member, the two adjusting screws 621 are disposed in the two accommodating grooves 32, the two adjusting screws 621 are rotatably connected with the bottom wall of the accommodating groove 32, one ends of the two clamping blocks 61 near the bottom wall of the accommodating groove 32 are provided with threaded holes along the sliding direction of the clamping blocks 61, and the two adjusting screws 621 are respectively disposed in the threaded holes of the two clamping blocks 61 in a penetrating manner and are in threaded connection with the clamping blocks 61.
Referring to fig. 6, the transmission member includes racks 622, first connecting grooves 33 with the two accommodating grooves 32 are formed on sidewalls of the two accommodating grooves 32 along a direction perpendicular to the supporting plate 111, the racks 622 are provided with two, one of the racks 622 is slidably disposed in one of the first connecting grooves 33, the other rack 622 is slidably disposed in the other first connecting groove 33, gears 6211 are coaxially and fixedly disposed on the two adjusting screws 621, and the racks 622 are engaged with the gears 6211.
Referring to fig. 6, the side walls of the two first connecting grooves 33 are provided with second connecting grooves 34 communicated with the placing groove 31 along the sliding direction of the rack 622, connecting rods 341 are provided in the two second connecting grooves 34 in a sliding manner, a pressing block 35 is provided in the placing groove 31 along the sliding direction of the rack 622 in a sliding manner, two ends of the connecting rods 341 are fixedly connected with the pressing block 35 and the rack 622 respectively, and a rubber pad 351 is adhered to one end, far away from the bottom wall of the placing groove 31, of the pressing block 35.
When the reagent tube 2 is put into the placing groove 31, the bottom end of the reagent tube 2 is abutted against the surface of the pressing block 35, the reagent tube 2 is continuously pressed down to push the pressing block 35 to slide towards the direction close to the bottom wall of the placing groove 31, the two racks 622 are driven to slide in the first connecting groove 33 respectively, the racks 622 are meshed with the gear 6211, the gears 6211 are driven to rotate by sliding the racks 622, the two adjusting screw 621 are driven to rotate by the two racks 622 respectively, the adjusting screw 621 is connected with the clamping blocks 61 in a threaded manner, and the two adjusting screw 621 rotate and simultaneously drive the two clamping blocks 61 to slide in the accommodating groove 32 respectively, so that the two clamping blocks 61 are close to each other, and the reagent tube 2 is clamped and fixed.
Referring to fig. 6, a first pushing member for driving the pressing block 35 to slide away from the bottom wall of the placing groove 31 is arranged in the placing groove 31, the first pushing member comprises a spring 36, the spring 36 is arranged in the placing groove 31, one end of the spring 36 is abutted with the bottom wall of the placing groove 31, and the other end of the spring 36 is abutted with the pressing block 35; when the reagent vessel 2 needs to be removed, the pressing block 35 slides in a direction away from the bottom wall of the placement groove 31 under the action of the elastic force of the spring 36, so that the two clamping blocks 61 are away from each other, and the reagent vessel 2 can be removed.
Referring to fig. 6 and 7, a limiting member for limiting sliding of the pressing block 35 is arranged in the placing groove 31, the limiting member comprises a limiting block 37, a limiting groove 352 is formed in the side wall of the pressing block 35 along the sliding direction of the pressing block 35, the limiting block 37 is arranged in the limiting groove 352 in a sliding manner, an elastic member 353 for driving the limiting block 37 to slide away from the bottom wall of the limiting groove 352 is arranged in the limiting groove 352, the elastic member 353 comprises a pressure spring, one end of the pressure spring is abutted with the bottom wall of the limiting groove 352, the other end of the pressure spring is abutted with the limiting block 37, and a clamping groove 311 for inserting the limiting block 37 is formed in the side wall of the placing groove 31; the briquetting 35 is in the in-process of sliding to being close to standing groove 31 diapire direction, and stopper 37 is in spacing groove 352 all the time, and when two clamp pieces 61 pressed from both sides tight to reagent pipe 2, stopper 37 is just right with draw-in groove 311 to through the elasticity effect of pressure spring, make stopper 37 insert draw-in groove 311, realize the spacing to briquetting 35.
Referring to fig. 7, a second pushing member for pushing the limiting block 37 out of the clamping groove 311 is arranged on the detection platform 3, the second pushing member comprises a push rod 38, a through hole 39 communicated with the clamping groove 311 is formed in the side wall of the detection platform 3 along the direction that the limiting block 37 is inserted into the clamping groove 311, the push rod 38 is slidably arranged in the through hole 39, anti-falling blocks 381 are welded at two ends of the push rod 38, a second tension spring 382 is sleeved on the push rod 38, the second tension spring 382 is positioned in the clamping groove 311, one end of the second tension spring 382 is fixedly connected with the bottom wall of the clamping groove 311, and the other end of the second tension spring 382 is fixedly connected with the anti-falling block 381 positioned in the clamping groove 311.
The implementation principle of the virus detection device for improving detection safety in the embodiment of the application is as follows: the extracted virus reagent is stored in the reagent tube 2 and sealed by the sealing cap 21; when detecting viruses, the reagent tube 2 filled with viruses is placed in the placing groove 31 on the detecting table 3, the reagent tube 2 is pressed down, the reagent tube 2 pushes the pressing block 35 to slide towards the direction close to the bottom wall of the placing groove 31, and the two racks 622 are driven to slide in the first connecting groove 33 respectively, so that the two adjusting screws 621 are driven to rotate through the gear 6211, and the two adjusting screws 621 are driven to slide in the accommodating groove 32 simultaneously when rotating, so that the two clamping blocks 61 are driven to be close to each other, and the reagent tube 2 is clamped.
Then, starting the first rodless cylinder to drive the detection platform 3 to slide, enabling the detection platform 3 to enter the detection box 1 from the box inlet 12 of the detection box 1, and sealing the box inlet 12 through the sealing plate 121; after the reagent tube 2 enters the detection box 1, the second rodless cylinder drives the mounting plate 16 box to slide in the direction close to the reagent tube 2, the plug 411 on the connecting sleeve 41 is inserted into the plug groove 2121 on the sealing cover 21, and then the driving cylinder drives the connecting sleeve 41 to slide upwards, so that the sealing cover 21 and the reagent tube 2 can be separated.
The reagent tube 2 is slid to the position opposite to the injection needle 512, the reaction reagent is injected into the reagent tube 2 through the liquid guide tube 511 and the injection needle 512 by the injector 51, and then the reagent tube 2 is slid to the observation position of the microscope 52, and virus is detected; in the detection process of the virus, the virus is not easy to flow along with air, and is attached to the clothes of a detection person or directly enters the detection person through the respiratory tract, so that the safety of the virus detection is high.
The foregoing are all preferred embodiments of the present application, and are not intended to limit the scope of the present application in any way, therefore: all equivalent changes in structure, shape and principle of this application should be covered in the protection scope of this application.

Claims (5)

1. A virus detection device for improving detection safety, characterized in that: the device comprises a detection box (1) and a reagent tube (2) for storing virus reagents, wherein a sealing cover (21) is arranged on the reagent tube (2), a detection table (3) is arranged in the detection box (1) in a sliding manner, a clamping mechanism (6) for fixing the reagent tube (2) is arranged on the detection table (3), a first driving piece (11) for driving the detection table (3) to slide is arranged in the detection box (1), a box inlet (12) for allowing the detection table (3) to slide out is formed in the detection box (1), and a sealing plate (121) for sealing the box inlet (12) is arranged on the detection box (1); a cover opening assembly (4) for opening or closing a sealing cover (21) on the reagent tube (2) and a detection assembly (5) for detecting virus reagents are arranged in the detection box (1);
the detection table (3) is provided with a placing groove (31) for placing the reagent tube (2), the clamping mechanism (6) comprises clamping blocks (61) and a driving assembly (62), the two clamping blocks (61) are arranged, the side wall of the placing groove (31) is provided with two containing grooves (32) communicated with the placing groove (31), the two clamping blocks (61) are respectively arranged in the two containing grooves (32) in a sliding mode, and the driving assembly (62) is used for driving the two clamping blocks (61) to be close to or far away from each other;
the driving assembly (62) comprises an adjusting screw (621) and a transmission piece, the adjusting screw (621) is rotatably arranged in each of the two accommodating grooves (32), a threaded hole is formed in one end, close to the bottom wall of the accommodating groove (32), of the clamping block (61) along the sliding direction of the clamping block (61), the adjusting screw (621) penetrates through the threaded hole and is in threaded connection with the clamping block (61), and the transmission piece is used for driving the two adjusting screws (621) to rotate simultaneously;
the transmission piece comprises racks (622), a first connecting groove (33) is formed in the side wall of the accommodating groove (32) along the sliding direction of the vertical clamping block (61), the racks (622) are all arranged in the first connecting groove (33) in a sliding mode, gears (6211) are all coaxially and fixedly arranged on the two adjusting screws (621), the racks (622) are meshed with the gears (6211), a second connecting groove (34) communicated with the placing groove (31) is formed in the side wall of the first connecting groove (33) along the sliding direction of the racks (622), a pressing block (35) is arranged in the placing groove (31) in a sliding mode along the sliding direction of the racks (622), the two racks (622) are fixedly connected with the pressing block (35), and a first pushing piece for driving the pressing block (35) to slide is arranged in the placing groove (31);
the first pushing piece comprises a spring (36), the spring (36) is arranged in the placing groove (31), one end of the spring (36) is abutted against the bottom wall of the placing groove (31), the other end of the spring (36) is abutted against the pressing block (35), and a limiting piece for limiting the sliding of the pressing block (35) is arranged in the placing groove (31);
limiting parts include stopper (37), spacing groove (352) have been seted up along the slip direction of perpendicular briquetting (35) to the lateral wall of briquetting (35), stopper (37) slip sets up in spacing groove (352), be provided with in spacing groove (352) and be used for driving stopper (37) to keeping away from gliding elastic component (353) of spacing groove (352) diapire direction, draw-in groove (311) that are used for supplying stopper (37) male are seted up to the lateral wall of standing groove (31), be provided with on detecting platform (3) and be used for ejecting the second pushing away from of draw-in groove (311) with stopper (37).
2. A virus detection device for improving detection safety according to claim 1, wherein: and anti-slip pads (611) are arranged at the ends, close to each other, of the two clamping blocks (61), and the anti-slip pads (611) are made of elastic materials.
3. A virus detection device for improving detection safety according to claim 1, wherein: the cover opening assembly (4) comprises a connecting sleeve (41), a second driving piece (42) and a third driving piece (43), wherein a mounting plate (16) is arranged in the detection box (1) in a sliding manner along the direction of the bottom wall of the parallel detection box (1), the second driving piece (42) is used for driving the mounting plate (16) to slide, the connecting sleeve (41) is arranged on the mounting plate (16) in a sliding manner along the direction of the vertical mounting plate (16), the third driving piece (43) is arranged on the mounting plate (16), the third driving piece (43) is used for driving the connecting sleeve (41) to slide, an inserting block (411) is fixedly arranged on the connecting sleeve (41), the sealing cover (21) is buckled on the reagent tube (2), and an inserting groove (2121) for the inserting block (411) to be inserted is formed in the sealing cover (21).
4. A virus detection device for improving detection safety according to claim 1, wherein: the detection assembly (5) comprises an injector (51) and a microscope (52), wherein the injector (51) is fixedly arranged on the detection box (1), the injector (51) is internally used for storing reaction reagents, an injection needle (512) is communicated with the injector (51), the injection needle (512) is fixedly arranged in the detection box (1), and the microscope (52) is fixedly arranged on the top wall of the detection box (1).
5. A virus detection device for improving detection safety according to claim 1, wherein: the detection box (1) is fixedly provided with a liquid storage tank (17), disinfectant is stored in the liquid storage tank (17), a spray head (173) is communicated with the liquid storage tank (17), the spray head (173) extends into the detection box (1), and a water pump (171) for conveying the disinfectant to the spray head (173) is arranged on the liquid storage tank (17).
CN202111459462.6A 2021-12-02 2021-12-02 Virus detection device for improving detection safety Active CN114217060B (en)

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CN114397168B (en) * 2022-03-28 2022-06-17 江西汉氏医学发展有限公司 Internet-based body fluid balance intelligent health detection equipment and detection method
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CN210742274U (en) * 2019-08-29 2020-06-12 中国农业科学院北京畜牧兽医研究所 Canine coronavirus separation and detection kit
CN213407145U (en) * 2020-09-23 2021-06-11 深圳市金阅科技有限责任公司 Foot-and-mouth disease O type virus detects anti-infection device
CN112300922A (en) * 2020-11-09 2021-02-02 宿州市鑫尧健康科技有限公司 Gene detection device in field of biotechnology
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