CN211445731U

CN211445731U - Equipment is deposited to pyrosequencing method detection KRAS gene mutation detect reagent

Info

Publication number: CN211445731U
Application number: CN201920863389.0U
Authority: CN
Inventors: 丁岩
Original assignee: Gene Biotechnology Dalian Co ltd
Current assignee: Gene Biotechnology Dalian Co ltd
Priority date: 2019-06-10
Filing date: 2019-06-10
Publication date: 2020-09-08
Anticipated expiration: 2029-06-10

Abstract

The utility model discloses a pyrosequencing method detects KRAS gene mutation detect reagent and deposits equipment, concretely relates to smart machine technical field, including box and case lid, the case lid is installed to box top adaptation, the case lid lower surface is provided with and pushes down the subassembly, install a set of backing plate on the box is inside along the horizontal direction, fixed mounting has the multiunit to separate the baffle on the backing plate, it all is provided with fastening components to separate the baffle both sides, fastening components internally mounted has the reagent pipe, the inside bottom of box is provided with lifting unit. The utility model discloses a set up lifting unit, rotatory dwang can drive the fly leaf and rise to with reagent pipe jack-up, made things convenient for the staff to take to the reagent pipe, provided higher simple operation nature, caused the unrestrained phenomenon of inside reagent when having avoided the staff to take the reagent pipe, provided higher operational safety nature.

Description

Equipment is deposited to pyrosequencing method detection KRAS gene mutation detect reagent

Technical Field

The utility model relates to an intelligent equipment technical field, more specifically say, the utility model relates to a sequencing method of pyrophosphoric acid detects KRAS gene mutation detect reagent and deposits equipment.

Background

Pyrophosphoric acid, colorless viscous liquid, generate crystal after long-term storage, is colorless glass, pyrophosphate has strong coordination, is commonly used as a catalyst in industry, is prepared with organic phosphate and the like, and in the detection process of KRAS gene mutation by a pyrosequencing method, relevant storage equipment is required to be used for storing a detection reagent so as to ensure the activity of the reagent.

The existing detection reagent storage equipment still has more defects that a reagent tube is placed in an equipment mounting groove in the using process, a certain elastic fastening effect exists between the general reagent tube and the equipment, reagent in the reagent tube is easy to spill when workers take the reagent tube with strong force, the operation safety is poor, the problem that the reagent tube is easy to spill when a part of the reagent tube in the reagent storage equipment is covered by a cover in the prior art is urgently needed to be solved, in addition, some detection reagent storage equipment is not firm at present, the reagent tube is easy to shake due to unstable fixation between the reagent tube and a box body in the transportation process, and the stability of a pyrophosphoric acid reagent is seriously influenced.

SUMMERY OF THE UTILITY MODEL

In order to overcome the above-mentioned defect of prior art, the embodiment of the utility model provides a pyrosequencing method detects KRAS gene mutation detect reagent and deposits equipment, through having set up lifting unit, rotatory dwang can drive the fly leaf and rise to with reagent pipe jack-up, made things convenient for the staff to take to reagent pipe, higher simple operation nature is provided, cause the unrestrained phenomenon of inside reagent when having avoided the staff to take the reagent pipe, higher operational safety is provided.

In order to achieve the above object, the utility model provides a following technical scheme: a storage device for KRAS gene mutation detection reagents by a pyrosequencing method comprises a box body and a box cover, wherein the box cover is arranged above the box body in a matched mode, a pressing assembly is arranged on the lower surface of the box cover, a group of base plates are arranged in the box body in the horizontal direction, a plurality of groups of partition plates are fixedly arranged on the base plates, fastening assemblies are arranged on two sides of each partition plate, reagent tubes are arranged in the fastening assemblies, and a lifting assembly is arranged at the bottom end in the box body;

lifting unit is including the dwang, the fixed rolling disc that has cup jointed in dwang one end, the fixed cover of dwang outside is equipped with the fixed block, the dwang outside is close to fixed block one side and is provided with first guide block, and the dwang outside is close to the fixed block opposite side and is provided with the second guide block, first guide block top articulates there is first movable rod, second guide block top articulates there is the second movable rod, the fly leaf is installed to second movable rod top, the fly leaf top has set firmly the multiunit cushion.

In a preferred embodiment, the pressing assembly includes an action spring, a pressing plate is fixedly connected to the lower surface of the action spring, and a silica gel pad is bonded to the lower surface of the pressing plate.

In a preferred embodiment, the fastening assembly includes a fixing plate, a first extrusion spring is fixedly connected to the side surface of the fixing plate along the horizontal direction, a second extrusion spring is arranged below the side surface of the fixing plate close to the first extrusion spring, a first extrusion plate is installed at one end of the first extrusion spring, and a second extrusion plate is installed at one end of the second extrusion spring.

In a preferred embodiment, the rotation levers are connected to the first guide block and the second guide block, respectively, by screwing.

In a preferred embodiment, the outer surface of the swivelling lever is provided with two sets of oppositely distributed threads.

In a preferred embodiment, the first movable rod and the second movable rod are both rotatably connected with the movable plate.

In a preferred embodiment, the first compression plate and the second compression plate are both designed in an arc structure, and protective cotton is bonded inside the first compression plate and the second compression plate.

In a preferred embodiment, the length of the first compression spring is smaller than the length of the second compression spring.

In a preferred embodiment, the box body and the box cover are hinged together, and a group of cushion feet are installed at four corner positions of the lower surface of the box body.

The utility model discloses a technological effect and advantage:

1. the utility model discloses in through having set up lifting unit, rotatory dwang can drive the fly leaf and rise to jack up the reagent pipe, made things convenient for the staff to take the reagent pipe, provided higher convenience of operation, avoided the staff to cause the phenomenon that inside reagent spills when taking the reagent pipe, provided higher operational safety;

2. the utility model discloses in through having set up push down subassembly and fastening components, fastened fast to the reagent pipe by the first stripper plate and the second stripper plate of equidimension not, made things convenient for the staff to place, and the effect of cooperation push down plate can be fastened the reagent pipe from the top, fastens the reagent pipe from all-round, has guaranteed the stability between reagent pipe and the box, has avoided taking place the phenomenon of rocking in the transportation.

Drawings

Fig. 1 is a schematic view of the overall structure of the present invention.

Fig. 2 is a schematic structural view of the middle lifting assembly of the present invention.

Fig. 3 is an enlarged schematic structural view of a portion a in fig. 1 according to the present invention.

Fig. 4 is an enlarged schematic structural view of a portion B in fig. 1 according to the present invention.

Fig. 5 is a schematic structural diagram of the first pressing plate of the present invention.

The reference signs are: the device comprises a box body 1, a box cover 2, a pressing component 3, an action spring 31, a pressing plate 32, a silica gel pad 33, a baffle 4, a fastening component 5, a fixed plate 51, a first extrusion spring 52, a first extrusion plate 53, a second extrusion spring 54, a second extrusion plate 55, a reagent tube 6, a backing plate 7, a lifting component 8, a rotating rod 81, a rotating disc 82, a fixed block 83, a first guide block 84, a second guide block 85, a first movable rod 86, a second movable rod 87, a movable plate 88 and a cushion block 89.

Detailed Description

The technical solutions in the embodiments of the present invention will be described clearly and completely with reference to the accompanying drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative work belong to the protection scope of the present invention.

The reagent storage equipment for detecting KRAS gene mutation by a pyrosequencing method as shown in attached figures 1 and 2 comprises a box body 1 and a box cover 2, wherein the box cover 2 is installed above the box body 1 in a matched manner, a lower pressing assembly 3 is arranged on the lower surface of the box cover 2, a group of base plates 7 are installed in the box body 1 along the horizontal direction, a plurality of groups of partition baffles 4 are fixedly installed on the base plates 7, fastening assemblies 5 are arranged on two sides of each partition baffle 4, reagent tubes 6 are installed in the fastening assemblies 5, and a lifting assembly 8 is arranged at the bottom end in the box body 1;

the lifting assembly 8 comprises a rotating rod 81, a rotating disc 82 is fixedly sleeved at one end of the rotating rod 81, a fixed block 83 is fixedly sleeved outside the rotating rod 81, a first guide block 84 is arranged on one side, close to the fixed block 83, of the outside of the rotating rod 81, a second guide block 85 is arranged on the other side, close to the fixed block 83, of the outside of the rotating rod 81, a first movable rod 86 is hinged above the first guide block 84, a second movable rod 87 is hinged above the second guide block 85, a movable plate 88 is arranged above the second movable rod 87, and a plurality of groups of cushion blocks 89 are fixedly arranged above the movable plate 88;

the rotating rod 81 is respectively connected with the first guide block 84 and the second guide block 85 in a threaded rotating manner;

two sets of reversely distributed threads are arranged on the outer surface of the rotating rod 81;

the first movable rod 86 and the second movable rod 87 are both rotatably connected with the movable plate 88;

the box body 1 is hinged with the box cover 2, and a group of cushion feet are arranged at four corners of the lower surface of the box body 1.

The implementation mode is specifically as follows: when the box cover 2 is opened by a worker, when the reagent tube 6 in the box body 1 needs to be taken out, the worker holds the rotating disc 82 to rotate the rotating rod 81, when the rotating rod 81 is in a rotating process, the first guide block 84 and the second guide block 85 on the rotating rod 81 can move towards the middle simultaneously, when the rotating rod moves in the same direction, the first movable rod 86 and the second movable rod 87 can also be drawn together along with the rotating rod, the movable plate 88 is upwards jacked, and therefore the reagent tube 6 on each cushion block 89 is upwards jacked, due to the design, the rotating rod 81 can drive the movable plate 88 to ascend, so that the reagent tube 6 is jacked up, the worker can conveniently take the reagent tube 6, high operation convenience is provided, the phenomenon that the reagent tube 6 is splashed when the worker takes the reagent tube 6 is avoided, and high operation safety is provided.

The KRAS gene mutation detection reagent storage equipment adopting the pyrosequencing method as shown in the attached figures 1, 3, 4 and 5 further comprises a pressing component 3, wherein the pressing component 3 is arranged below the box cover 2, the pressing component 3 comprises an action spring 31, a lower pressing plate 32 is fixedly connected to the lower surface of the action spring 31, and a silica gel pad 33 is bonded to the lower surface of the lower pressing plate 32;

the fastening assembly 5 comprises a fixed plate 51, a first extrusion spring 52 is fixedly connected to the side surface of the fixed plate 51 along the horizontal direction, a second extrusion spring 54 is arranged below the side surface of the fixed plate 51 close to the first extrusion spring 52, a first extrusion plate 53 is installed at one end of the first extrusion spring 52, and a second extrusion plate 55 is installed at one end of the second extrusion spring 54;

the first extrusion plate 53 and the second extrusion plate 55 are both designed to be arc-shaped structures, and protective cotton is bonded inside the first extrusion plate 53 and the second extrusion plate 55;

the length of the first pressing spring 52 is smaller than the length of the second pressing spring 54.

The implementation mode is specifically as follows: the worker holds the top end of the reagent tube 6, the bottom end of the reagent tube 6 slowly extends downwards into the fastening assembly 5, because the length of the first extrusion spring 52 is smaller than that of the second extrusion spring 54, the width between the two groups of first extrusion plates 53 is larger than that between the two groups of second extrusion plates 55, the bottom end of the reagent tube 6 is firstly contacted with the two groups of first extrusion plates 53 with the size of one, and then moves downwards, the outer wall of the reagent tube 6 is contacted with the second extrusion plates 55, the compressed first extrusion springs 52 and second extrusion springs 54 need to be reset respectively, so that the first extrusion plates 53 and second extrusion plates 55 are pushed from two sides to extrude the reagent tube 6, the reagent tube 6 can be rapidly fixed, then the box cover 2 is closed, the pressing assembly 3 on the box cover 2 works, the action spring 31 presses the pressing plate 32, and the silica gel pad 33 is contacted with the top end of the reagent tube 6, the reagent tube 6 is pushed downwards, so that the reagent tube 6 which is not completely placed in is completely pushed in, and the stability between the reagent tube 6 and the box body 1 is kept.

The utility model discloses the theory of operation:

referring to the attached

drawings

1 and 2 of the specification, by arranging the lifting assembly 8, the movable plate 88 can be driven to ascend by rotating the rotating rod 81, so that the reagent tube 6 is jacked up, a worker can conveniently take the reagent tube 6, high operation convenience is provided, the phenomenon that an internal reagent is scattered when the worker takes the reagent tube 6 is avoided, and high operation safety is provided;

refer to description figure 1, figure 3, figure 4 and figure 5, through having set up push down subassembly 3 and fastening components 5, fasten reagent pipe 6 fast by not equidimension first stripper plate 53 and second stripper plate 55, made things convenient for the staff to place, and the effect of cooperation holding down plate 32, can fasten reagent pipe 6 from the top, fasten reagent pipe 6 from the all-round, guaranteed the stability between reagent pipe 6 and the box 1, the phenomenon of rocking has been avoided taking place in the transportation.

The points to be finally explained are: first, in the description of the present application, it should be noted that, unless otherwise specified and limited, the terms "mounted," "connected," and "connected" should be understood broadly, and may be a mechanical connection or an electrical connection, or a communication between two elements, and may be a direct connection, and "upper," "lower," "left," and "right" are only used to indicate a relative positional relationship, and when the absolute position of the object to be described is changed, the relative positional relationship may be changed;

secondly, the method comprises the following steps: in the drawings of the disclosed embodiments of the present invention, only the structures related to the disclosed embodiments are referred to, and other structures can refer to the common design, and under the condition of no conflict, the same embodiment and different embodiments of the present invention can be combined with each other;

and finally: the above description is only for the preferred embodiment of the present invention and should not be taken as limiting the invention, and any modifications, equivalent replacements, improvements, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims

1. The utility model provides an equipment is deposited to pyrosequencing method detection KRAS gene mutation detect reagent, includes box (1) and case lid (2), its characterized in that: a box cover (2) is installed above the box body (1) in a matched mode, a pressing assembly (3) is arranged on the lower surface of the box cover (2), a group of backing plates (7) are installed in the box body (1) in the horizontal direction, a plurality of groups of partition plates (4) are fixedly installed on the backing plates (7), fastening assemblies (5) are arranged on two sides of each partition plate (4), reagent tubes (6) are installed in the fastening assemblies (5), and a lifting assembly (8) is arranged at the bottom end in the box body (1);

lifting unit (8) are including dwang (81), dwang (81) one end is fixed to be cup jointed has rolling disc (82), dwang (81) outside fixed cover is equipped with fixed block (83), dwang (81) outside is close to fixed block (83) one side and is provided with first guide block (84), and dwang (81) outside is close to fixed block (83) opposite side and is provided with second guide block (85), first guide block (84) top articulates there is first movable rod (86), second guide block (85) top articulates there is second movable rod (87), fly leaf (88) is installed to second movable rod (87) top, fly leaf (88) top has set firmly multiunit cushion (89).

2. The apparatus for storing reagent for detecting KRAS gene mutation according to claim 1, wherein: the pressing assembly (3) comprises an action spring (31), a pressing plate (32) is fixedly connected to the lower surface of the action spring (31), and a silica gel pad (33) is bonded to the lower surface of the pressing plate (32).

3. The apparatus for storing reagent for detecting KRAS gene mutation according to claim 1, wherein: fastening components (5) are including fixed plate (51), the rigid coupling has first extrusion spring (52) on the fixed plate (51) side surface along the horizontal direction, and fixed plate (51) side surface is close to first extrusion spring (52) below and is provided with second extrusion spring (54), first stripper plate (53) is installed to first extrusion spring (52) one end, second stripper plate (55) is installed to second extrusion spring (54) one end.

4. The apparatus for storing reagent for detecting KRAS gene mutation according to claim 1, wherein: the rotating rod (81) is connected with the first guide block (84) and the second guide block (85) in a threaded rotating mode.

5. The apparatus for storing reagent for detecting KRAS gene mutation according to claim 1, wherein: the surface of dwang (81) is provided with two sets of reverse distribution's screw thread.

6. The apparatus for storing reagent for detecting KRAS gene mutation according to claim 1, wherein: the first movable rod (86) and the second movable rod (87) are rotatably connected with the movable plate (88).

7. The apparatus for storing reagent for detecting KRAS gene mutation according to claim 2, wherein: the first extrusion plate (53) and the second extrusion plate (55) are both in arc-shaped structural design, and protective cotton is bonded in the first extrusion plate (53) and the second extrusion plate (55).

8. The apparatus for storing reagent for detecting KRAS gene mutation according to claim 2, wherein: the length of the first pressing spring (52) is smaller than the length of the second pressing spring (54).

9. The apparatus for storing reagent for detecting KRAS gene mutation according to claim 1, wherein: the box body (1) is hinged with the box cover (2), and a group of cushion feet are arranged at four corners of the lower surface of the box body (1).