CN114181810A

CN114181810A - Based on little biological detection equipment for bio-pharmaceuticals

Info

Publication number: CN114181810A
Application number: CN202111366272.XA
Authority: CN
Inventors: 郭庆芳
Original assignee: Individual
Current assignee: Individual
Priority date: 2021-11-18
Filing date: 2021-11-18
Publication date: 2022-03-15

Abstract

The invention discloses a microbial detection device for bio-pharmaceuticals, which comprises a body and an extraction pipe arranged outside the body, wherein a disinfection sampling mechanism is arranged outside the body; carry out slowly transferring through the transmission wheel pair extraction tube, make shower nozzle spun alcohol can carry out abundant sterilization and disinfection to the surface of extraction tube, and simultaneously, can wipe the surface of extraction tube through the cotton piece of alcohol, make the extraction tube surface after being cleaned and disinfected more clean, design through the scraper blade, can strike off completely the remaining alcohol stain in extraction tube surface after cleaning, thereby can guarantee that the extraction tube surface that gets into in the microbial cultivation jar of bio-pharmaceuticals is in sterile condition, avoided the extraction tube directly to carry out the sample extraction through artifical manual injection in the cultivation jar and make its surface-adhering bacterial microorganism can be brought into and lead to in the cultivation jar that the microbial pharmaceuticals liquid receives the condition emergence of pollution for bio-pharmaceuticals in the cultivation jar.

Description

Based on little biological detection equipment for bio-pharmaceuticals

Technical Field

The invention relates to the technical field of biological pharmacy, in particular to a microbial detection device based on biological pharmacy.

Background

The microorganisms comprise microorganisms such as bacteria, viruses and fungi, and in the nature, the types of the microorganisms are various, some microorganisms are harmful to human health, and some microorganisms are beneficial to human health, so that in the field of biological pharmacy, part of beneficial microorganisms are cultured to prepare a medicament for treating human health diseases. In the process of bio-pharmaceuticals, microorganisms and liquid medicine need to be mixed and cultured through a biological culture technology, so as to obtain a microbial liquid medicine, and in the process of preparing the microbial liquid medicine, in order to ensure that the distribution and content of the microorganisms in the liquid medicine can meet the requirement of medicament preparation, the distribution and content of the microorganisms in the microbial liquid medicine generally need to be detected. In the testing process, the extraction microorganism liquid medicine that carries out the microorganism liquid medicine in the extraction tube direct grafting entering culture tank on the operator with check out test set, but the extraction tube is at the in-process that gets into culture tank, and some microorganism in the outside air may be attached to the surface of extraction tube, then enters into the inside to culture tank along with the extraction tube to can cause the pollution to the inside microorganism liquid medicine of culture tank, make bio-pharmaceuticals work receive and block, thereby be unfavorable for going on continuously of bio-pharmaceuticals work.

Disclosure of Invention

In order to solve the problem that the liquid medicine is easily polluted because external bacteria are easily brought into the microbial liquid medicine when the microbial detection equipment for the bio-pharmaceuticals performs detection sample sampling and realize the aim that the microbial liquid medicine is not easily polluted when the microbial detection equipment for the bio-pharmaceuticals performs detection sample sampling, the invention is realized by the following technical scheme: the utility model provides a microbial detection equipment based on bio-pharmaceuticals, includes the body and sets up at the outside extraction pipe of body, the outside of body is provided with disinfection sampling mechanism, disinfection sampling mechanism includes casing, drive wheel, walks tub groove, disinfection chamber, spraying disinfection subassembly, the cotton piece of alcohol, scraper blade, waste liquid collection subassembly, the outside of body is provided with the casing, the medial surface of casing is provided with the drive wheel, the medial surface of casing has been seted up and has been walked the tub groove, the disinfection chamber has been seted up to the medial surface of casing, the medial surface of disinfection chamber is provided with the cotton piece of alcohol, the bottom of disinfection chamber is provided with the scraper blade, the medial surface of casing is provided with spraying disinfection subassembly, the medial surface of casing is provided with waste liquid collection subassembly.

The spraying disinfection component comprises a screw rod, a moving block, a movable plate, a pressure-reducing spring, an extrusion plate, a liquid guide groove, a sprayer, a linkage rod, disinfection alcohol and a liquid storage cavity, wherein the inner side surface of the shell is provided with the liquid storage cavity, the inner side surface of the liquid storage cavity is provided with the screw rod, the outer surface of the screw rod is provided with the movable plate, the linkage rod is arranged outside the movable plate, the movable plate is arranged outside the linkage rod, the pressure-reducing spring is arranged at the top of the movable plate, the extrusion plate is arranged at the top of the pressure-reducing spring, the liquid guide groove is formed in the inner side surface of the shell, the sprayer is arranged on the inner side surface of the disinfection cavity, the disinfection alcohol is filled in the liquid storage cavity, and the surface of the extraction pipe can be sufficiently sterilized and disinfected by spraying the disinfection alcohol.

The waste liquid collecting assembly comprises a collecting cavity, an upper liquid guiding groove and a lower liquid guiding groove, wherein the collecting cavity is formed in the inner side face of the shell, the upper liquid guiding groove is formed in the inner side face of the shell, the lower liquid guiding groove is formed in the inner side face of the shell, the residual disinfection alcohol on the surface of the extraction pipe when moving downwards can be completely scraped and drained to the scraped disinfection alcohol, the disinfection alcohol behind the cleaning extraction pipe can slide along the outer surface of the scraper to the upper liquid guiding groove and enter the collecting cavity, the residual microbial liquid on the surface of the extraction pipe when moving upwards can be scraped through the lower surface of the scraper, and the scraped microbial liquid is collected along the lower surface of the scraper to the inside of the lower liquid guiding groove and enters the collecting cavity.

Furthermore, the number of drive wheels is two, two the drive wheels symmetric distribution is in walking both ends about the pipe groove for can carry out the microorganism liquid medicine sample of detecting to the extraction tube downstream, walk the pipe groove top-down and run through the casing.

Further, the shape of alcohol cotton piece is the ring form, circle size and extraction pipe are corresponding in the alcohol cotton piece, the shape of scraper blade is cavity frustum form, top notch size is corresponding with the extraction pipe on the scraper blade for can fully contact with the medial surface of alcohol cotton piece and scraper blade when the extraction pipe removes, thereby can carry out cleaning to the surface of extraction pipe better.

Furthermore, the screw rod is double-thread rod, the quantity of the moving block and the linkage rods is two groups and is symmetrically distributed at the left end and the right end of the screw rod, the upper end and the lower end of the linkage rods are respectively connected with the movable plate and the moving block in a rotating mode, the movable plate and the extrusion plate are both connected with the inner side face of the liquid storage cavity in a sliding mode, and the top of the extrusion plate in the liquid storage cavity is filled with the disinfection alcohol.

Furthermore, the liquid guide groove is communicated with the liquid storage cavity, the liquid guide groove is communicated with the spray heads, the number of the spray heads is at least five, and all the spray heads are distributed on the inner side surface of the disinfection cavity at equal angles, so that the outer surface of the extraction pipe can be sufficiently disinfected by the disinfection alcohol sprayed by the spray heads.

Furthermore, the left end and the right end of the upper liquid guiding groove and the left end and the right end of the lower liquid guiding groove are respectively communicated with the disinfection cavity and the collection cavity, the upper liquid guiding groove corresponds to the upper surface of the scraper, and the lower liquid guiding groove corresponds to the lower surface of the scraper.

Further, the inside of body is provided with complementary unit, complementary unit includes line wheel, stay cord, torsional spring, trough, adsorbs the cover, the medial surface of body is provided with the line wheel, the surface of line wheel is provided with the torsional spring, the surface rolling of line wheel has the stay cord, the trough has been seted up to the medial surface of body, the bottom of casing is provided with adsorbs the cover, through adsorbing the cover for the casing can be fixed the casing with stable absorption at the blake jar surface when taking a sample the during operation, thereby makes the casing can keep stable state in the course of the work, simultaneously, through mutually supporting between stay cord, line wheel, the torsional spring, can remove it under casing non-operating condition and tie, makes the casing also can keep stable state under non-operating condition.

Further, the medial surface fixed connection of torsional spring and body, the medial surface sliding connection of stay cord and trough, the surface fixed connection of stay cord and casing, the line wheel the stay cord the torsional spring the quantity of trough is two and equal symmetric distribution at the upper and lower both ends of casing.

The invention provides a microbial detection device for bio-pharmaceuticals. The method has the following beneficial effects:

1. the microbial detection equipment for the bio-pharmaceuticals is characterized in that the extraction pipe is slowly lowered through the transmission wheel, so that the alcohol sprayed by the spray head can fully sterilize the outer surface of the extraction pipe, meanwhile, the surface of the extraction tube can be wiped through the alcohol cotton block, so that the surface of the cleaned and disinfected extraction tube is cleaner, moreover, through the design of the scraper, residual alcohol stains on the surface of the cleaned extraction pipe can be completely scraped, thereby can guarantee to get into the extraction tube surface in the microbial cultivation jar of bio-pharmaceuticals and be in sterile condition, avoid the extraction tube directly to carry out the sample extraction through artifical manual injection in the culture jar and make its surface adnexed bacterial microorganism can be brought into to lead to in the culture jar that the microbial medicine liquid for bio-pharmaceuticals receives the condition emergence of polluting, thereby can guarantee going on smoothly of bio-pharmaceuticals work.

2. This microbial detection equipment based on bio-pharmaceuticals, through adsorbing the cover, the line wheel, mutually support between stay cord and the torsional spring, can all keep stable state at the casing under work and unoperated state, avoided the casing stability relatively poor under operating condition to lead to the condition emergence that produces the hindrance to inspection sample extraction work, thereby can guarantee going on smoothly of bio-pharmaceuticals microbial detection work, make can carry out better detection to the distribution situation of microorganism in the microbial medicine liquid, be favorable to going on continuously of bio-pharmaceuticals work.

Drawings

FIG. 1 is a schematic view of the present invention in partial cross section;

FIG. 2 is an enlarged view of the structure at A in FIG. 1 according to the present invention;

FIG. 3 is a schematic view of the internal structure of the housing according to the present invention;

FIG. 4 is an enlarged view of the structure at B in FIG. 3 according to the present invention;

FIG. 5 is an enlarged view of the structure of FIG. 3 at C according to the present invention;

FIG. 6 is an enlarged view of the structure shown in FIG. 3;

fig. 7 is a schematic perspective view of the scraper of the present invention.

In the figure: 1. a body; 2. an extraction pipe; 3. a sterilization sampling mechanism; 31. a housing; 32. a driving wheel; 33. a pipe running groove; 34. a disinfection chamber; 35. a spray disinfection assembly; 351. a screw; 352. a moving block; 353. a movable plate; 354. a pressure relief spring; 355. a pressing plate; 356. a spray head; 357. a linkage rod; 358. disinfecting alcohol; 359. a liquid storage cavity; 3510. a liquid guide groove; 36. alcohol cotton blocks; 37. a squeegee; 38. a waste liquid collection assembly; 381. a collection chamber; 382. an upper liquid guiding groove; 383. a lower liquid drainage tank; 4. an auxiliary mechanism; 41. a wire wheel; 42. pulling a rope; 43. a torsion spring; 44. a wiring groove; 45. and (4) adsorbing the cover.

Detailed description of the preferred embodiment 1

The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.

An example of the apparatus for detecting microorganisms for biopharmaceuticals is as follows:

referring to fig. 1-7, a microbial detection device for bio-pharmaceuticals comprises a body 1 and an extraction tube 2 disposed outside the body 1, a disinfection sampling mechanism 3 is disposed outside the body 1, the disinfection sampling mechanism 3 comprises a housing 31, a transmission wheel 32, a tube-passing groove 33, a disinfection chamber 34, a spray disinfection component 35, an alcohol cotton block 36, a scraper 37, and a waste liquid collection component 38, a housing 31 is disposed outside the body 1, the transmission wheel 32 is disposed on the inner side surface of the housing 31, the tube-passing groove 33 is disposed on the inner side surface of the housing 31, the number of the transmission wheels 32 is two, the two transmission wheels 32 are symmetrically disposed at the left and right ends of the tube-passing groove 33, so that the extraction tube 2 can be conveyed downwards to sample a microbial liquid detection sample, and the tube-passing groove 33 penetrates through the housing 31 from top to bottom.

Disinfection chamber 34 has been seted up to casing 31's medial surface, disinfection chamber 34's medial surface is provided with the cotton piece of alcohol 36, disinfection chamber 34's bottom is provided with scraper blade 37, the shape of cotton piece of alcohol 36 is the ring form, circle size and extraction tube 2 are corresponding in the cotton piece of alcohol 36, scraper blade 37's shape is the cavity frustum form, scraper blade 37 goes up top notch size and extraction tube 2 are corresponding, can fully contact with the medial surface of cotton piece of alcohol 36 and scraper blade 37 when making extraction tube 2 remove, thereby can carry out cleaning to the surface of extraction tube 2 better, casing 31's medial surface is provided with spraying disinfection subassembly 35, casing 31's medial surface is provided with waste liquid collection subassembly 38.

The spraying disinfection component 35 comprises a screw 351, a movable block 352, a movable plate 353, a pressure-relieving spring 354, a squeezing plate 355, a liquid guide groove 3510, a spray head 356, a linkage rod 357, disinfection alcohol 358 and a liquid storage cavity 359, wherein the inner side surface of the shell 31 is provided with the liquid storage cavity 359, the inner side surface of the liquid storage cavity 359 is provided with the screw 351, the outer surface of the screw 351 is provided with the movable block 352, the outer part of the movable block 352 is provided with the linkage rod 357, the outer part of the linkage rod 357 is provided with the movable plate 353, the top of the movable plate 353 is provided with the pressure-relieving spring 354, the top of the pressure-relieving spring 354 is provided with the squeezing plate 355, the inner side surface of the shell 31 is provided with the liquid guide groove 3510, the inner side surface of the disinfection cavity 34 is provided with the spray head 356, the interior of the liquid storage cavity 359 is filled with the disinfection alcohol 358, the surface of the extraction pipe 2 can be sufficiently sterilized and disinfected by spraying the disinfection alcohol 358, the liquid guide groove 3510 is communicated with the liquid storage cavity 359, the liquid guide groove 3510 is communicated with the spray head 356, the number of the spray heads 356 is at least five, and all the spray heads 356 are equiangularly distributed on the inner side of the sterilizing chamber 34, so that the sterilizing alcohol 358 sprayed from the spray heads 356 can sufficiently sterilize the outer surface of the extraction tube 2.

Screw rod 351 is double thread pole, the quantity of movable block 352 and gangbar 357 is two sets of and equal symmetric distribution both ends about screw rod 351, the upper and lower both ends of gangbar 357 rotate with fly leaf 353 and movable block 352 respectively and are connected, fly leaf 353 and stripper plate 355 all with the medial surface sliding connection of stock solution chamber 359, disinfection alcohol 358 fills in stock solution chamber 359 inside stripper plate 355 top position, liquid guide groove 3510 is linked together with stock solution chamber 359, liquid guide groove 3510 is linked together with shower nozzle 356, the quantity of shower nozzle 356 is five groups at least, all shower nozzles 356 equiangular distribution are at the medial surface of disinfection chamber 34, make shower nozzle 356 spun disinfection alcohol 358 can carry out abundant disinfection to the surface of extraction pipe 2.

The waste liquid collecting assembly 38 comprises a collecting cavity 381, an upper liquid guiding groove 382 and a lower liquid guiding groove 383, wherein the inner side surface of the shell 31 is provided with the collecting cavity 381, the inner side surface of the shell 31 is provided with the upper liquid guiding groove 382, the inner side surface of the shell 31 is provided with the lower liquid guiding groove 383, the upper surface of the scraper 37 can completely scrape the residual disinfecting alcohol 358 on the surface of the extraction tube 2 when moving downwards and guide the scraped disinfecting alcohol 358, so that the disinfecting alcohol 358 after cleaning the extraction tube 2 can slide to the upper liquid guiding groove 382 along the outer surface of the scraper 37 and enter the collecting cavity 381, meanwhile, the residual microbial liquid on the surface of the extraction tube 2 when moving upwards can be scraped through the lower surface of the scraper 37, the scraped microbial liquid slides to the inside of the lower liquid guiding groove 383 along the lower surface of the scraper 37 and enters the collecting cavity 381 for collecting treatment, the left end and the right end of the upper liquid guiding groove 382 and the lower liquid guiding groove 383 are respectively communicated with the disinfecting cavity 34 and the collecting cavity 381, the upper liquid-introducing groove 382 is positioned to correspond to the upper surface of the squeegee 37, and the lower liquid-introducing groove 383 is positioned to correspond to the lower surface of the squeegee 37.

The inside of body 1 is provided with complementary unit 4, complementary unit 4 includes line wheel 41, stay cord 42, torsional spring 43, trough 44, adsorb cover 45, the medial surface of body 1 is provided with line wheel 41, the surface of line wheel 41 is provided with torsional spring 43, the surface rolling of line wheel 41 has stay cord 42, trough 44 has been seted up to the medial surface of body 1, the bottom of casing 31 is provided with adsorb cover 45, through adsorbing cover 45, make casing 31 stably adsorb the fixing at the blake jar outer surface with casing 31 when carrying out sample work, thereby make casing 31 can remain stable state in the course of the work, and simultaneously, through stay cord 42, line wheel 41, mutually support between torsional spring 43, can remove it and tie under casing 31 non-operating condition, make casing 31 also can keep stable state under non-operating condition.

Torsion spring 43 is fixedly connected with the inner side surface of body 1, stay cord 42 is connected with the inner side surface of cabling channel 44 in a sliding manner, stay cord 42 is fixedly connected with the outer surface of casing 31, and the number of reel 41, stay cord 42, torsion spring 43 and cabling channel 44 is two and is distributed at the upper and lower ends of casing 31 symmetrically.

When the detection sample extraction and detection are required to be carried out by the microbial detection equipment for bio-pharmaceuticals, an operator inserts the extraction pipe 2 into the pipe running groove 33, so that the two driving wheels 32 rotate to drive the extraction pipe 2 to slowly move downwards, meanwhile, the screw 351 rotates to drive the moving block 352 to move, under the transmission action of the linkage rod 357, the moving plate 353 moves upwards and drives the pressure-reducing spring 354 to move upwards, the pressure-reducing spring 354 moves upwards to drive the extrusion plate 355 to move upwards, the extrusion plate 355 can extrude the disinfection alcohol 358 in the liquid storage cavity 359 in the upward moving process, so that the disinfection alcohol 358 is conveyed to the spray head 356 through the liquid guide groove 10 and is sprayed out to the inside of the disinfection cavity 34, when the extraction pipe 2 passes through the disinfection cavity 34, the outer surface of the extraction pipe can be fully covered by the disinfection alcohol 358 sprayed out by the spray head 356, thereby the surface of the extraction pipe can be well sterilized and disinfected, the disinfecting alcohol 358 sprayed inside the disinfecting chamber 34 falls on and is absorbed by the alcohol pad 36, so that the alcohol pad 36 also contains a large amount of alcohol, and therefore, when the extraction tube 2 passes through the alcohol pad 36, the outer surface of the extraction tube 2 can be disinfected again, and meanwhile, impurities attached to the outer surface of the extraction tube 2 can be wiped off;

with the continuous downward movement of the extraction tube 2, the extraction tube 2 passes through the scraper 37, when the extraction tube 2 passes through the scraper 37, under the scraping action of the scraper 37, residual alcohol on the surface of the extraction tube 2 can be scraped by the scraper 37 and slides downwards along the upper surface of the scraper 37, and enters the collection cavity 381 through the upper liquid guiding groove 382, so that the outer surface of the extraction tube 2 passing through the inside of the shell 31 can keep a clean and sterile state, and the condition that microbial medicine liquid in the culture tank is polluted due to the fact that external microbes are brought into the inside of the culture tank when a sample is extracted is avoided, so that the stability in the production process of the biopharmaceutical microbial medicine liquid is greatly improved, and the continuous operation of the biopharmaceutical work is facilitated;

as the amount of the alcohol cotton block 36 absorbing the disinfecting alcohol 358 increases, the content of the disinfecting alcohol 358 therein gradually reaches a saturated state, the disinfecting alcohol 358 within the interior drips from the bottom of the alcohol cotton block 36 and travels along the upper drainage channel 382 into the collection chamber 381 for collection, and, when the aspiration tube 2 is moved upwardly after completing the sample aspiration task, under the action of the scraper 37, the microbial medicine liquid adhered to the surface of the extraction tube 2 is scraped and slides down along the lower surface of the scraper 37 to the liquid guiding groove 383 and enters the collection cavity 381 through the liquid guiding groove 383, and is sterilized again through the upper alcohol cotton block 36, therefore, the extraction pipe 2 can be cleaned and sterilized when entering and exiting the culture tank, so that the microbial detection equipment for the bio-pharmaceuticals has better safety and functionality in the actual use process, and can meet the actual use requirement;

when needs examine microorganism liquid medicine sample, the operator places casing 31 on the blake pot, can adsorb cover 45 through pushing down, make adsorb cover 45 can stably adsorb and fix the surface at the blake pot, thereby make casing 31 stability in the actual work in-process better, simultaneously when need not use, through line wheel 41, stay cord 42, under the mutually supporting between the torsional spring 43, can tie casing 31's removal, make casing 31 also can keep the stable state under the non-operating condition, and still can not produce the hindrance to casing 31's normal work, make the practicality of microorganism testing equipment in the in-service use process better.

Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.

Claims

1. The utility model provides a microbial detection equipment for based on bio-pharmaceuticals, includes body (1) and sets up extraction tube (2) outside body (1), its characterized in that: the body (1) is externally provided with a disinfection sampling mechanism (3), the disinfection sampling mechanism (3) comprises a shell (31), a driving wheel (32), a pipe trough (33), a disinfection cavity (34), a spray disinfection component (35), an alcohol cotton block (36), a scraper (37) and a waste liquid collecting component (38), a shell (31) is arranged outside the body (1), a driving wheel (32) is arranged on the inner side surface of the shell (31), the inner side surface of the shell (31) is provided with a pipe running groove (33), the inner side surface of the shell (31) is provided with a disinfection cavity (34), the inner side surface of the disinfection cavity (34) is provided with an alcohol cotton block (36), the bottom of the disinfection cavity (34) is provided with a scraper (37), a spraying and disinfecting assembly (35) is arranged on the inner side surface of the shell (31), and a waste liquid collecting assembly (38) is arranged on the inner side surface of the shell (31);

the spraying and disinfecting assembly (35) comprises a screw rod (351), a movable block (352), a movable plate (353), a pressure-relieving spring (354), a squeezing plate (355), a liquid guide groove (3510), a spray head (356), a linkage rod (357), disinfecting alcohol (358) and a liquid storage cavity (359), wherein the liquid storage cavity (359) is arranged on the inner side surface of the shell (31), the screw rod (351) is arranged on the inner side surface of the liquid storage cavity (359), the movable block (352) is arranged on the outer surface of the screw rod (351), the linkage rod (357) is arranged outside the movable block (352), the movable plate (353) is arranged outside the linkage rod (357), the pressure-relieving spring (354) is arranged at the top of the movable plate (353), the squeezing plate (355) is arranged at the top of the pressure-relieving spring (354), the liquid guide groove (3510) is arranged on the inner side surface of the shell (31), and the spray head (356) is arranged on the inner side surface of the disinfecting cavity (34), the interior of the liquid storage cavity (359) is filled with sterilized alcohol (358);

the waste liquid collecting assembly (38) comprises a collecting cavity (381), an upper liquid guide groove (382) and a lower liquid guide groove (383), the collecting cavity (381) is formed in the inner side surface of the shell (31), the upper liquid guide groove (382) is formed in the inner side surface of the shell (31), and the lower liquid guide groove (383) is formed in the inner side surface of the shell (31).

2. The apparatus for the detection of microorganisms based on biopharmaceuticals according to claim 1, wherein: the number of the transmission wheels (32) is two, the two transmission wheels (32) are symmetrically distributed at the left end and the right end of the pipe running groove (33), and the pipe running groove (33) penetrates through the shell (31) from top to bottom.

3. The apparatus for the detection of microorganisms based on biopharmaceuticals according to claim 1, wherein: the shape of alcohol cotton piece (36) is the ring form, circle size and extraction pipe (2) are corresponding in the last circle of alcohol cotton piece (36), the shape of scraper blade (37) is hollow frustum form, the last top notch size of scraper blade (37) is corresponding with extraction pipe (2).

4. The apparatus for the detection of microorganisms based on biopharmaceuticals according to claim 1, wherein: the utility model discloses a disinfection device, including screw rod (351), movable block (352) and gangbar (357), the quantity of screw rod (351) is two sets of and equal symmetric distribution is at both ends about screw rod (351), the upper and lower both ends of gangbar (357) rotate with fly leaf (353) and movable block (352) respectively and are connected, fly leaf (353) and stripper plate (355) all with the medial surface sliding connection of stock solution chamber (359), disinfection alcohol (358) are filled in stock solution chamber (359) inside stripper plate (355) top position.

5. The apparatus for the detection of microorganisms based on biopharmaceuticals according to claim 1, wherein: the liquid guide groove (3510) is communicated with the liquid storage cavity (359), the liquid guide groove (3510) is communicated with the spray heads (356), the number of the spray heads (356) is at least five, and all the spray heads (356) are distributed on the inner side surface of the disinfection cavity (34) at equal angles.

6. The apparatus for the detection of microorganisms based on biopharmaceuticals according to claim 1, wherein: the left end and the right end of the upper liquid guide groove (382) and the lower liquid guide groove (383) are respectively communicated with the disinfection cavity (34) and the collection cavity (381), the position of the upper liquid guide groove (382) corresponds to the upper surface of the scraper (37), and the position of the lower liquid guide groove (383) corresponds to the lower surface of the scraper (37).

7. The apparatus for the detection of microorganisms based on biopharmaceuticals according to claim 1, wherein: the inside of body (1) is provided with complementary unit (4), complementary unit (4) are including line wheel (41), stay cord (42), torsional spring (43), trough (44), adsorb cover (45), the medial surface of body (1) is provided with line wheel (41), the surface of line wheel (41) is provided with torsional spring (43), the surface rolling of line wheel (41) has stay cord (42), trough (44) have been seted up to the medial surface of body (1), the bottom of casing (31) is provided with adsorbs cover (45).

8. The apparatus for the detection of microorganisms based on biopharmaceuticals according to claim 7, wherein: the utility model discloses a novel wire winding device, including torsional spring (43), the medial surface fixed connection of body (1), stay cord (42) and wiring groove (44), the medial surface sliding connection of stay cord (42) and casing (31), line wheel (41) stay cord (42) torsional spring (43) the quantity of wiring groove (44) is two and equal symmetric distribution at the upper and lower both ends of casing (31).