CN114160013A - Paraffin refining and stirring equipment for Paracetamol, caffeine and chlorphenamine maleate sustained-release pellets and preparation process of wax refining and stirring equipment - Google Patents
Paraffin refining and stirring equipment for Paracetamol, caffeine and chlorphenamine maleate sustained-release pellets and preparation process of wax refining and stirring equipment Download PDFInfo
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- CN114160013A CN114160013A CN202111417455.XA CN202111417455A CN114160013A CN 114160013 A CN114160013 A CN 114160013A CN 202111417455 A CN202111417455 A CN 202111417455A CN 114160013 A CN114160013 A CN 114160013A
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- 238000003756 stirring Methods 0.000 title claims abstract description 106
- 238000007670 refining Methods 0.000 title claims abstract description 36
- 238000002360 preparation method Methods 0.000 title claims abstract description 28
- RZVAJINKPMORJF-UHFFFAOYSA-N Acetaminophen Chemical compound CC(=O)NC1=CC=C(O)C=C1 RZVAJINKPMORJF-UHFFFAOYSA-N 0.000 title claims abstract description 26
- 229960005489 paracetamol Drugs 0.000 title claims abstract description 25
- 239000008188 pellet Substances 0.000 title claims abstract description 22
- DBAKFASWICGISY-BTJKTKAUSA-N Chlorpheniramine maleate Chemical compound OC(=O)\C=C/C(O)=O.C=1C=CC=NC=1C(CCN(C)C)C1=CC=C(Cl)C=C1 DBAKFASWICGISY-BTJKTKAUSA-N 0.000 title claims abstract description 21
- 238000013268 sustained release Methods 0.000 title claims abstract description 21
- 239000012730 sustained-release form Substances 0.000 title claims abstract description 21
- RYYVLZVUVIJVGH-UHFFFAOYSA-N caffeine Chemical compound CN1C(=O)N(C)C(=O)C2=C1N=CN2C RYYVLZVUVIJVGH-UHFFFAOYSA-N 0.000 title description 12
- 239000001993 wax Substances 0.000 title description 9
- LPHGQDQBBGAPDZ-UHFFFAOYSA-N Isocaffeine Natural products CN1C(=O)N(C)C(=O)C2=C1N(C)C=N2 LPHGQDQBBGAPDZ-UHFFFAOYSA-N 0.000 title description 6
- 229960001948 caffeine Drugs 0.000 title description 6
- VJEONQKOZGKCAK-UHFFFAOYSA-N caffeine Natural products CN1C(=O)N(C)C(=O)C2=C1C=CN2C VJEONQKOZGKCAK-UHFFFAOYSA-N 0.000 title description 6
- 239000012188 paraffin wax Substances 0.000 title description 2
- 239000000463 material Substances 0.000 claims abstract description 69
- 239000003814 drug Substances 0.000 claims abstract description 18
- 238000000034 method Methods 0.000 claims abstract description 4
- 238000007599 discharging Methods 0.000 claims description 38
- 238000007789 sealing Methods 0.000 claims description 28
- 230000000694 effects Effects 0.000 claims description 10
- 238000003466 welding Methods 0.000 claims description 8
- 230000007306 turnover Effects 0.000 claims description 7
- 229940079593 drug Drugs 0.000 claims description 6
- 238000011144 upstream manufacturing Methods 0.000 claims description 3
- YGDVXSDNEFDTGV-UHFFFAOYSA-N 2-[6-[bis(carboxymethyl)amino]hexyl-(carboxymethyl)amino]acetic acid Chemical compound OC(=O)CN(CC(O)=O)CCCCCCN(CC(O)=O)CC(O)=O YGDVXSDNEFDTGV-UHFFFAOYSA-N 0.000 claims 4
- 241000209205 Coix Species 0.000 claims 4
- 230000003111 delayed effect Effects 0.000 claims 1
- 230000002787 reinforcement Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 abstract description 7
- 229940046978 chlorpheniramine maleate Drugs 0.000 abstract description 3
- 239000002699 waste material Substances 0.000 abstract description 2
- 230000003014 reinforcing effect Effects 0.000 description 4
- 235000010894 Artemisia argyi Nutrition 0.000 description 3
- NTYJJOPFIAHURM-UHFFFAOYSA-N Histamine Chemical compound NCCC1=CN=CN1 NTYJJOPFIAHURM-UHFFFAOYSA-N 0.000 description 3
- 244000030166 artemisia Species 0.000 description 3
- 230000015572 biosynthetic process Effects 0.000 description 3
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- 150000003180 prostaglandins Chemical class 0.000 description 3
- 238000003786 synthesis reaction Methods 0.000 description 3
- 230000001754 anti-pyretic effect Effects 0.000 description 2
- 210000003169 central nervous system Anatomy 0.000 description 2
- 230000002267 hypothalamic effect Effects 0.000 description 2
- 210000001503 joint Anatomy 0.000 description 2
- 239000012257 stirred material Substances 0.000 description 2
- 230000024883 vasodilation Effects 0.000 description 2
- 206010004542 Bezoar Diseases 0.000 description 1
- 206010059109 Cerebral vasoconstriction Diseases 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- GUGOEEXESWIERI-UHFFFAOYSA-N Terfenadine Chemical compound C1=CC(C(C)(C)C)=CC=C1C(O)CCCN1CCC(C(O)(C=2C=CC=CC=2)C=2C=CC=CC=2)CC1 GUGOEEXESWIERI-UHFFFAOYSA-N 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 230000001387 anti-histamine Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000002337 anti-port Effects 0.000 description 1
- 239000000739 antihistaminic agent Substances 0.000 description 1
- 239000002221 antipyretic Substances 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000033228 biological regulation Effects 0.000 description 1
- 230000005540 biological transmission Effects 0.000 description 1
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- 229960001231 choline Drugs 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 230000017525 heat dissipation Effects 0.000 description 1
- 229960001340 histamine Drugs 0.000 description 1
- 230000003340 mental effect Effects 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 210000002850 nasal mucosa Anatomy 0.000 description 1
- 210000001640 nerve ending Anatomy 0.000 description 1
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- 210000000929 nociceptor Anatomy 0.000 description 1
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- 150000003834 purine nucleoside derivatives Chemical class 0.000 description 1
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- Mixers Of The Rotary Stirring Type (AREA)
- Fertilizers (AREA)
- Apparatuses For Bulk Treatment Of Fruits And Vegetables And Apparatuses For Preparing Feeds (AREA)
Abstract
The invention relates to the technical field of medicine production devices, in particular to a wax refining and stirring device for an Paracetamol, chlorpheniramine maleate and chlorpheniramine maleate sustained-release pellet and a preparation process thereof, wherein the wax refining and stirring device comprises a main body, a supporting mechanism is arranged on the outer side of the main body, the bottom end of the main body is connected with an in-out mechanism, an adjusting mechanism is arranged on the in-out mechanism, a conveying mechanism is arranged on the in-out mechanism, and a stirring mechanism is arranged in the main body; the general inlet and outlet mechanism is arranged so as to be convenient for adding or taking materials into the main body, and all the adding and taking processes are carried out in a sealed state, so that air is isolated, and the phenomenon that the moxa is irritated to fill a production workshop is avoided; the adjusting mechanism can assist the conveying mechanism to better convey materials, control the conveying direction and avoid material leakage and waste; the stirring mechanism is arranged, so that the materials can be stirred fully and meticulously, the stirring task can be completed in the shortest time, and the medicine preparation efficiency is improved.
Description
Technical Field
The invention relates to the technical field of medicine production devices, in particular to a wax refining and stirring device for an Paracetamol, caffeine and chlorphenamine maleate sustained-release pellet and a preparation process thereof.
Background
Paracetamol and chlorphenamine maleate is a synthetic purine nucleoside analogue. The analgesic effect of acetaminophen may be through inhibition of prostaglandin synthesis in the central nervous system and blocking the impulses of pain nerve endings, which may be associated with inhibition of prostaglandin synthesis or other substances that sensitize pain receptors; antipyretic effects may be due to peripheral vasodilation, sweating and heat dissipation through hypothalamic thermoregulatory centers, and may be associated with hypothalamic inhibition of prostaglandin synthesis. The caffeine acts on the central nervous system of cerebral cortex in small dose to excite mental and relieve fatigue. It also can promote cerebral vasoconstriction and relieve headache caused by cerebral vasodilation. Chlorpheniramine maleate is an antihistamine, competitively blocks the action of histamine (H1) receptors, relieves allergic symptoms, resists the action of M choline receptors, and dries the nasal mucosa. The artificial bezoar has antipyretic and anti-inflammatory effects.
However, most of the wax refining and stirring devices of the existing Paracetamol and chlorphenamine maleate sustained-release pellets stir in an unsealed space, so that the pungent smell generated during the mixing of the medicines can influence the working environment of workers, and the long-time contact with the air during the stirring can influence the medicine property of the medicines, and even the medicines lose the treatment effect.
Disclosure of Invention
Aiming at the problems in the prior art, the invention provides a wax refining stirring device of an Paracetamol, caffeine and chlorphenamine maleate sustained-release pellet and a preparation process thereof.
The technical scheme adopted by the invention for solving the technical problems is as follows: the waxiness refining and stirring equipment for the Paracetamol, kaempferiae and chlorphenamine maleate sustained-release pellets comprises a main body, wherein a supporting mechanism is arranged on the outer side of the main body, an inlet and outlet mechanism is connected to the bottom end of the main body, an adjusting mechanism is installed on the inlet and outlet mechanism, a conveying mechanism is arranged on the inlet and outlet mechanism, and a stirring mechanism is installed inside the main body.
Specifically, the supporting mechanism includes the support, is cylindricly the main part be equipped with four supports for the outside, fixedly connected with strengthens the frame between the support, the mount has been cup jointed to the bottom of main part, the welding has the connecting block between mount and the strengthen the frame.
Specifically, business turn over mechanism includes the connecting pipe, the bottom welding of main part has the connecting pipe, the bottom of connecting pipe is connected with inlet pipe and discharging pipe, communicate with each other between connecting pipe, inlet pipe and the discharging pipe, the one end of inlet pipe is connected with the feeder hopper, feeder hopper and connecting pipe all are and leak hopper-shaped.
Specifically, adjustment mechanism includes first motor, install first motor between inlet pipe and the discharging pipe, the first gear of bottom fixedly connected with of first motor, one side meshing of first gear has second gear and opposite side meshing to have the third gear.
Specifically, a first sealing plate is fixedly connected to the second gear, a second sealing plate is fixedly connected to the third gear, the first sealing plate is sealed to the feeding pipe, and the second sealing plate is sealed to the discharging pipe.
Specifically, conveying mechanism includes the second motor, one side fixedly connected with second motor of connecting pipe, the first belt pulley of bottom fixedly connected with of second motor, the inside of connecting pipe is rotated and is connected with first pivot, the welding has the flight in the first pivot.
Specifically, the bottom fixedly connected with second belt pulley of first pivot, the winding has the connecting band between second belt pulley and the first belt pulley, first belt pulley is less than the diameter of second belt pulley.
Specifically, rabbling mechanism includes the third motor, the third motor is installed on the top of main part, the bottom fixedly connected with second pivot of third motor, the bottom of second pivot extends to the inside of main part, the outside cover of second pivot has the sleeve axle.
Specifically, the top fixed connection main part of cover axle, sliding connection has the slide-bar on the cover axle, be connected with the telescopic link between slide-bar and the cover axle, telescopic link drive slide-bar slides along the cover axle, fixedly connected with fourth gear and fifth gear on the slide-bar.
Specifically, fixedly connected with connecting rod in the second pivot, the both ends of connecting rod rotate respectively and are connected with the third pivot, the bottom fixedly connected with stirring frame of third pivot, the top fixedly connected with sixth gear and the seventh gear of third pivot, fifth gear and seventh gear engagement.
S1: when the main body is used for stirring operation, the main body is firstly moved to a required use position through the supporting mechanism, and the adding and discharging ports of the in-out mechanism are aligned to upstream and downstream equipment to complete preparation work;
s2: then starting the adjustment to close and open the corresponding channel, starting the conveying mechanism, adding the material to the vicinity of the conveying mechanism through the in-out mechanism, and conveying the material to the inside of the main body by the conveying mechanism in a relay manner, so that the material is stirred in the closed main body, the sharp smell is prevented from overflowing, and the quality of the medicine is improved;
s3: and finally, the stirring mechanism is started, the stirring assembly in the stirring mechanism rotates when the tool is used, the stirring effect is greatly improved, the stirring speed can be adjusted conveniently according to different materials by adjusting the stirring speed, the use flexibility of the equipment is improved, after the stirring is finished, the adjusting mechanism is operated to open and close corresponding channels, the conveying mechanism is started again to run reversely, and the discharging process is completed.
The invention has the beneficial effects that:
(1) according to the waxiness refining and stirring equipment for the amazamin sustained-release pellets and the preparation process of the waxiness refining and stirring equipment, the bottom end of the main body is connected with the feeding and discharging mechanism, the general feeding and discharging mechanism is arranged, so that feeding or discharging of materials inside the main body is facilitated, the feeding and discharging are all carried out in a sealed state, air is isolated, and the situation that the ai qi is stimulated to fill a production workshop is avoided, namely: the main part passes through the support and puts the workshop with the enhancement frame, when the inside of main part adds the material as required, at first adjust adjustment mechanism, it is unblocked to make the inlet pipe, and the discharging pipe is sealed, inject the material into on the feeder hopper, the inlet pipe is the slope setting, then near the material enters into near first pivot under the action of gravity, it piles up to pass through the inside that the main part was carried to the connecting pipe with the material through conveying mechanism, the main part is inclosed space, then rabbling mechanism all accomplishes the stirring operation in airtight space, the air has been completely cut off, avoid amazing chinese mugwort gas I fill the workshop.
(2) According to the wax refining and stirring equipment for the Paracetamol, chlorphenamine maleate and chlorphenamine maleate sustained-release pellets and the preparation process thereof, the inlet and outlet mechanism is provided with the adjusting mechanism, the inlet and outlet mechanism is provided with the conveying mechanism, the adjusting mechanism can assist the conveying mechanism to convey materials better, the conveying direction is controlled, and material leakage and waste are avoided, namely: when a conveying task is carried out, a first motor is started firstly, the first motor drives a first gear, the first gear is meshed with a second gear and a third gear simultaneously, a feeding pipe is not sealed by a first sealing plate, a discharging pipe is synchronously sealed by a second sealing plate, further, when materials are added, the materials are prevented from being thrown out of the discharging pipe, the materials can be smoothly conveyed into the main body, the second motor is started when the materials are conveyed, the second motor drives a first belt pulley at the bottom end to rotate, power is transmitted between the first belt pulley and a second belt pulley through a connecting belt, a first rotating shaft causes a spiral sheet to run, the spiral sheet sequentially delivers the materials to the inside of the main body, the purpose of adding the materials into the inside of the main body is achieved, after the materials are stirred, the first motor is started, the first sealing plate is driven to seal the feeding pipe, and meanwhile, the discharging pipe is not sealed by the second sealing plate, operation second motor antiport, then the material that stirs is discharged through the discharging pipe, has improved degree of automation and the efficiency of business turn over material toward the main part inside greatly.
(3) According to the waxiness refining and stirring equipment for the Paracetamol and chlorphenamine maleate sustained-release pellets and the preparation process thereof, the stirring mechanism is arranged in the main body, the stirring mechanism is arranged, so that the materials can be stirred fully and finely, the stirring task can be completed in the shortest time, and the drug preparation efficiency is improved, namely: after the medicine materials are added into the main body, a third motor is started, the third motor drives a second rotating shaft to rotate, the second rotating shaft drives two third rotating shafts to revolve around the second rotating shaft through connecting rods, a sleeve shaft is fixed in the main body and is in sliding connection with the sleeve shaft, a seventh gear and a fifth gear are mutually meshed, the third rotating shaft automatically transmits along with the seventh gear, so that the stirring rack is driven to revolve and simultaneously rotate, the stirring effect of the stirring rack is greatly improved, when the stirring speed of the stirring rack needs to be improved, a telescopic rod is started, the sliding shaft is driven to move along the sleeve shaft through the telescopic rod, the fourth gear is in butt joint engagement with the sixth gear, the diameter of the fourth gear is larger than that of the sixth gear, the rotating speed of the third rotating shaft is improved, further, the full and delicate stirring operation of the materials is facilitated, the stirring task is completed in the shortest time, and the medicine manufacturing efficiency is improved, the use effect of the device is improved by flexibly adjusting the speed.
Drawings
The invention is further illustrated with reference to the following figures and examples.
FIG. 1 is a schematic structural diagram of the overall structure of a preferred embodiment of a wax refining and stirring device for an Paracetamol and chlorphenamine maleate sustained-release pellet and a preparation process thereof provided by the invention;
FIG. 2 is a schematic view of the connection structure of the in-out mechanism, the conveying mechanism and the stirring mechanism shown in FIG. 1;
FIG. 3 is a schematic view showing a connection structure of the in-out mechanism, the conveying mechanism and the stirring mechanism shown in FIG. 1;
FIG. 4 is an enlarged view of the part A shown in FIG. 1;
FIG. 5 is an enlarged view of the portion B shown in FIG. 2;
fig. 6 is a wax refining stirring device of the Paracetamol, caffeine and chlorphenamine maleate sustained-release pellets and a preparation process flow chart thereof.
In the figure: 1. the device comprises a main body, 2, a supporting mechanism, 21, a support, 22, a reinforcing frame, 23, a fixing frame, 24, a connecting block, 3, an in-out mechanism, 31, a feeding pipe, 32, a discharging pipe, 33, a feeding hopper, 34, a connecting pipe, 4, an adjusting mechanism, 41, a first motor, 42, a first gear, 43, a second gear, 44, a third gear, 45, a first sealing plate, 46, a second sealing plate, 5, a conveying mechanism, 51, a second motor, 52, a first belt pulley, 53, a second belt pulley, 54, a connecting belt, 55, a first rotating shaft, 56, a spiral sheet, 6, a stirring mechanism, 61, a third motor, 62, a second rotating shaft, 63, a sleeve shaft, 64, a sliding shaft, 65, a fourth gear, 66, a fifth gear, 67, a connecting rod, 68, a third rotating shaft, 69, a sixth gear, 69a, a seventh gear, 69b, a stirring frame, 69c and a telescopic rod.
Detailed Description
In order to make the technical means, the creation characteristics, the achievement purposes and the effects of the invention easy to understand, the invention is further described with the specific embodiments.
As shown in fig. 1-6, the wax refining and stirring device for the Paracetamol and chlorphenamine maleate sustained-release pellets and the preparation process thereof provided by the invention comprise a main body 1, wherein a supporting mechanism 2 is arranged on the outer side of the main body 1, an in-out mechanism 3 is connected to the bottom end of the main body 1, an adjusting mechanism 4 is installed on the in-out mechanism 3, a conveying mechanism 5 is arranged on the in-out mechanism 3, and a stirring mechanism 6 is installed inside the main body 1.
Specifically, supporting mechanism 2 includes support 21, is cylindricly main part 1 be equipped with four supports 21 for the outside, fixedly connected with reinforcing frame 22 between the support 21, mount 23 has been cup jointed to the bottom of main part 1, the welding has connecting block 24 between mount 23 and the reinforcing frame 22.
Specifically, the in-out mechanism 3 comprises a connecting pipe 34, the connecting pipe 34 is welded at the bottom end of the main body 1, the bottom end of the connecting pipe 34 is connected with a feeding pipe 31 and a discharging pipe 32, the connecting pipe 34, the feeding pipe 31 and the discharging pipe 32 are communicated, one end of the feeding pipe 31 is connected with a feeding hopper 33, and the feeding hopper 33 and the connecting pipe 34 are funnel-shaped; the bottom of main part 1 is connected with business turn over mechanism 3, and is general business turn over mechanism 3 set up and then be convenient for toward main part 1's inside adds the material or gets the material, and adds and gets the material and all adopt to go on under encapsulated situation, has completely cut off the air, avoids amazing chinese mugwort gas I to fill the workshop, promptly: the main part 1 is through support 21 with strengthen frame 22 and settles the workshop, when needs to go to the inside of main part 1 adds the material, at first adjust adjustment mechanism 4 makes inlet pipe 32 unblocked, and discharging pipe 32 seals, injects the material into on feeder hopper 33, inlet pipe 31 is the slope setting, then the material enters into near first pivot 55 under the action of gravity, through conveying mechanism 5 with the material pass through connecting pipe 34 carry the inside of main part 1 is piled up, main part 1 is airtight space, then rabbling mechanism 6 all accomplishes the stirring operation in airtight space, has isolated the air, avoids amazing chinese mugwort gas I fill the workshop.
Specifically, adjustment mechanism 4 includes first motor 41, install first motor 41 between inlet pipe 31 and the discharging pipe 32, the bottom fixedly connected with first gear 42 of first motor 41, one side meshing of first gear 42 has second gear 43 and the opposite side meshing has third gear 44.
Specifically, a first sealing plate 45 is fixedly connected to the second gear 43, a second sealing plate 46 is fixedly connected to the third gear 44, the first sealing plate 45 seals the feeding pipe 31, and the second sealing plate 46 seals the discharging pipe 32.
Specifically, conveying mechanism 5 includes second motor 51, one side fixedly connected with second motor 51 of connecting pipe 34, the first belt pulley 52 of bottom fixedly connected with of second motor 51, the inside of connecting pipe 34 is rotated and is connected with first pivot 55, the welding has flight 56 on the first pivot 55.
Specifically, a second belt pulley 53 is fixedly connected to the bottom end of the first rotating shaft 55, a connecting belt 54 is wound between the second belt pulley 53 and the first belt pulley 52, and the diameter of the first belt pulley 52 is smaller than that of the second belt pulley 53; install adjustment mechanism 4 on the business turn over mechanism 3, be equipped with conveying mechanism 5 on the business turn over mechanism 3, through adjustment mechanism 4 can assist conveying mechanism 5 better transport material controls direction of delivery, avoids the material to reveal extravagantly, promptly: when a conveying task is performed, the first motor 41 is firstly started, the first motor 41 drives the first gear 42, the first gear 42 simultaneously engages with the second gear 43 and the third gear 44, the first sealing plate 45 does not seal the feeding pipe 31, the second sealing plate 46 synchronously seals the discharging pipe 32, and further, when materials are added, the materials are prevented from being thrown out of the discharging pipe 32, the materials can be smoothly conveyed into the interior of the main body 1, the second motor 51 is started when the materials are conveyed, the second motor 51 drives the first belt pulley 52 at the bottom end to rotate, the first belt pulley 52 and the second belt pulley 53 are in power transmission through the connecting belt 54, the first rotating shaft 55 causes the spiral piece 56 to operate, and the spiral piece 56 sequentially conveys the materials to the interior of the main body 1, therefore, the purpose of adding materials into the main body 1 is achieved, after the materials are stirred, the first motor 41 is started to drive the first sealing plate 45 to seal the feeding pipe 31, meanwhile, the second sealing plate 46 does not seal the discharging pipe 32, the second motor 51 is operated to rotate in the reverse direction, and the stirred materials are discharged through the discharging pipe 32, so that the automation degree and the efficiency of feeding and discharging materials into and out of the main body 1 are greatly improved.
Specifically, rabbling mechanism 6 includes third motor 61, third motor 61 is installed on the top of main part 1, the bottom fixedly connected with second pivot 62 of third motor 61, the bottom of second pivot 62 extends to the inside of main part 1, the outside cover of second pivot 62 has sleeve 63.
Specifically, the top end of the sleeve 63 is fixedly connected with the main body 1, a sliding shaft 64 is connected to the sleeve 63 in a sliding manner, an expansion rod 69c is connected between the sliding shaft 64 and the sleeve 63, the expansion rod 69c drives the sliding shaft 64 to slide along the sleeve 63, and a fourth gear 65 and a fifth gear 66 are fixedly connected to the sliding shaft 64.
Specifically, a connecting rod 67 is fixedly connected to the second rotating shaft 62, two ends of the connecting rod 67 are respectively and rotatably connected to a third rotating shaft 68, a stirring frame 69b is fixedly connected to the bottom end of the third rotating shaft 68, a sixth gear 69 and a seventh gear 69a are fixedly connected to the top end of the third rotating shaft 68, and the fifth gear 66 is meshed with the seventh gear 69 a; internally mounted has rabbling mechanism 6 on the main part 1, through the setting of rabbling mechanism 6 and then be convenient for carry out abundant careful stirring operation to the material, accomplish the stirring task in the shortest time, improve the efficiency of preparation medicine, promptly: after the medicine materials are added into the main body 1, the third motor 61 is started, the third motor 61 drives the second rotating shaft 62 to rotate, the second rotating shaft 62 drives the two third rotating shafts 68 to revolve around the second rotating shaft 62 through the connecting rod 67, the sleeve shaft 63 is fixed inside the main body 1, the sliding shaft 64 is connected with the sleeve shaft 63 in a sliding manner, the seventh gear 69a and the fifth gear 66 are meshed with each other, the third rotating shaft 68 is transmitted with the seventh gear 69a, so that the stirring rack 69b is driven to revolve and rotate simultaneously, the stirring effect of the stirring rack 69b is greatly improved, when the stirring speed of the stirring rack 69b needs to be improved, the telescopic rod 69c is started, the sliding shaft 64 is driven to move along the sleeve shaft 63 through the telescopic rod 69c, and the fourth gear 65 is butted and meshed with the sixth gear 69, at this time, the diameter of the fourth gear 65 is larger than that of the sixth gear 69, so that the rotation speed of the third rotating shaft 68 is increased, thereby facilitating the fully and carefully stirring operation of the material, completing the stirring task in the shortest time, improving the efficiency of preparing the medicine, flexibly adjusting the speed, and improving the use effect of the device.
S1: when the main body 1 is used for stirring operation, firstly, the main body 1 is moved to a required use position through the supporting mechanism 2, and the adding and discharging ports of the in-out mechanism 3 are aligned to upstream and downstream equipment to complete preparation work;
s2: then starting the adjustment mechanism 4 to close and open a corresponding channel, starting the conveying mechanism 5, adding the materials to the vicinity of the conveying mechanism 5 through the in-out mechanism 3, and conveying the materials to the inside of the main body 1 by the conveying mechanism 5 in a relay manner, so that the materials are stirred in the closed main body 1, thereby avoiding the sharp odor from overflowing and improving the quality of the medicines;
s3: and finally, the stirring mechanism 6 is started, the stirring assembly inside the stirring mechanism 6 rotates when the tool is used, the stirring effect is greatly improved, the stirring speed can be adjusted conveniently according to different materials by adjusting the stirring speed, the use flexibility of the equipment is improved, after the stirring is finished, the adjusting mechanism 4 is operated to open and close corresponding channels, the conveying mechanism 6 runs in the reverse direction again, and the discharging process is completed.
When the device is used, a main body 1 is arranged in a production workshop through a support 21 and a reinforcing frame 22, when materials need to be added into the main body 1, firstly, an adjusting mechanism 4 is adjusted to ensure that a feeding pipe 32 is smooth, a discharging pipe 32 is closed, the materials are injected onto a feeding hopper 33, the feeding pipe 31 is obliquely arranged, the materials enter the vicinity of a first rotating shaft 55 under the action of gravity, the materials are conveyed into the main body 1 through a connecting pipe 34 through a conveying mechanism 5 and are accumulated, the main body 1 is a closed space, and stirring operation of a stirring mechanism 6 is completed in the closed space, so that air is isolated, and the phenomenon that moxa gas is irritated to fill the production workshop is avoided; when a conveying task is performed, firstly, the first motor 41 is started, the first motor 41 drives the first gear 42, the first gear 42 simultaneously engages with the second gear 43 and the third gear 44, the first sealing plate 45 is not in sealing with the feeding pipe 31, the second sealing plate 46 synchronously seals with the discharging pipe 32, further, when materials are added, the materials are prevented from being thrown out of the discharging pipe 32, the materials can be smoothly conveyed into the main body 1, the second motor 51 is started when the materials are conveyed, the second motor 51 drives the first belt pulley 52 at the bottom end to rotate, power is transmitted between the first belt pulley 52 and the second belt pulley 53 through the connecting belt 54, the first rotating shaft 55 causes the spiral piece 56 to operate, the spiral piece 56 sequentially delivers the materials into the main body 1, so that the purpose of adding the materials into the main body 1 is completed, after the materials are stirred, the first motor 41 is started to drive the first sealing plate 45 to seal with the feeding pipe 31, meanwhile, the second sealing plate 46 is not used for sealing the discharge pipe 32, the second motor 51 is operated to rotate reversely, and the stirred materials are discharged through the discharge pipe 32, so that the automation degree and efficiency of feeding and discharging materials into and out of the main body 1 are greatly improved; after the medicine materials are added into the main body 1, the third motor 61 is started, the third motor 61 drives the second rotating shaft 62 to rotate, the second rotating shaft 62 drives the two third rotating shafts 68 to revolve around the second rotating shaft 62 through the connecting rod 67, the sleeve shaft 63 is fixed in the main body 1, the sliding shaft 64 is connected with the sleeve shaft 63 in a sliding manner, the seventh gear 69a is meshed with the fifth gear 66, the third rotating shaft 68 is issued and transmitted along with the seventh gear 69a, so that the stirring frame 69b is driven to revolve and rotate simultaneously, the stirring effect of the stirring frame 69b is greatly improved, when the stirring speed of the stirring frame 69b needs to be improved, the telescopic rod 69c is started, the sliding shaft 64 is driven to move along the sleeve shaft 63 through the telescopic rod 69c, the fourth gear 65 is in butt joint meshing with the sixth gear 69, at the moment, the diameter of the fourth gear 65 is larger than that of the sixth gear 69, the rotating speed of the third rotating shaft 68 is improved, and then be convenient for carry out abundant careful stirring operation to the material, accomplish the stirring task in the shortest time, improve the efficiency of preparation medicine, the mode of nimble regulation rate has improved the result of use of device.
It will be evident to those skilled in the art that the invention is not limited to the details of the foregoing illustrative embodiments, and that the present invention may be embodied in other specific forms without departing from the spirit or essential attributes thereof. The present embodiments are therefore to be considered in all respects as illustrative and not restrictive, the scope of the invention being indicated by the appended claims rather than by the foregoing description, and all changes which come within the meaning and range of equivalency of the claims are therefore intended to be embraced therein. Any reference sign in a claim should not be construed as limiting the claim concerned.
Furthermore, it should be understood that although the present description refers to embodiments, not every embodiment may contain only a single embodiment, and such description is for clarity only, and those skilled in the art should integrate the description, and the embodiments may be combined as appropriate to form other embodiments understood by those skilled in the art.
Claims (10)
1. The waxiness refining and stirring equipment for the Paracetamol, kaempferiae and chlorphenamine maleate sustained-release pellets and the preparation process of the waxiness refining and stirring equipment are characterized by comprising a main body (1), a supporting mechanism (2) is arranged on the outer side of the main body (1), an inlet and outlet mechanism (3) is connected to the bottom end of the main body (1), an adjusting mechanism (4) is installed on the inlet and outlet mechanism (3), a conveying mechanism (5) is arranged on the inlet and outlet mechanism (3), and a stirring mechanism (6) is installed inside the main body (1).
2. The wax refining and stirring device for the Paracetamol, kahuangmin and chlorphenamine maleate sustained-release pellets and the preparation process thereof according to claim 1, wherein the wax refining and stirring device comprises: supporting mechanism (2) are cylindricly including support (21) be equipped with four support (21) for the outside of main part (1), fixedly connected with strengthens frame (22) between support (21), mount (23) have been cup jointed to the bottom of main part (1), the welding has connecting block (24) between mount (23) and the reinforcement frame (22).
3. The wax refining and stirring device for the Paracetamol, kahuangmin and chlorphenamine maleate sustained-release pellets and the preparation process thereof according to claim 1, wherein the wax refining and stirring device comprises: business turn over mechanism (3) is including connecting pipe (34), the bottom welding of main part (1) has connecting pipe (34), the bottom of connecting pipe (34) is connected with inlet pipe (31) and discharging pipe (32), communicate with each other between connecting pipe (34), inlet pipe (31) and discharging pipe (32), the one end of inlet pipe (31) is connected with feeder hopper (33), feeder hopper (33) and connecting pipe (34) all are hourglass hopper-shaped.
4. The wax refining and stirring device for the Paracetamol, Coix amcamide and Hexamethylene diamine tetraacetic acid (Ikame) sustained-release pellets and the preparation process thereof according to claim 3, wherein the wax refining and stirring device comprises: adjustment mechanism (4) include first motor (41), install first motor (41) between inlet pipe (31) and discharging pipe (32), the first gear (42) of bottom fixedly connected with of first motor (41), one side meshing of first gear (42) has second gear (43) and the opposite side meshing has third gear (44).
5. The wax refining and stirring device for the Paracetamol, Coix amcamide and Hexamethylene diamine tetraacetic acid (Ikame) sustained-release pellets and the preparation process thereof according to claim 4, wherein the wax refining and stirring device comprises: the feeding pipe is characterized in that a first sealing plate (45) is fixedly connected to the second gear (43), a second sealing plate (46) is fixedly connected to the third gear (44), the first sealing plate (45) seals the feeding pipe (31), and the second sealing plate (46) seals the discharging pipe (32).
6. The wax refining and stirring device for the Paracetamol, Coix amcamide and Hexamethylene diamine tetraacetic acid (Ikame) sustained-release pellets and the preparation process thereof according to claim 3, wherein the wax refining and stirring device comprises: conveying mechanism (5) include second motor (51), one side fixedly connected with second motor (51) of connecting pipe (34), the first belt pulley (52) of bottom fixedly connected with of second motor (51), the internal rotation of connecting pipe (34) is connected with first pivot (55), the welding has flight (56) on first pivot (55).
7. The wax refining and stirring device for the Paracetamol, Coix amcamide and Hexamethylene diamine tetraacetic acid (Ikame) delayed release pellets and the preparation process thereof according to claim 6, wherein the wax refining and stirring device comprises: the bottom fixedly connected with second belt pulley (53) of first pivot (55), it has connecting band (54) to twine between second belt pulley (53) and first belt pulley (52), first belt pulley (52) are less than the diameter of second belt pulley (53).
8. The wax refining and stirring device for the Paracetamol, kahuangmin and chlorphenamine maleate sustained-release pellets and the preparation process thereof according to claim 1, wherein the wax refining and stirring device comprises: rabbling mechanism (6) include third motor (61), third motor (61) are installed on the top of main part (1), the bottom fixedly connected with second pivot (62) of third motor (61), the bottom of second pivot (62) extends to the inside of main part (1), the outside cover of second pivot (62) has sleeve axle (63).
9. The wax refining and stirring device for the Paracetamol, kahuangmin and chlorphenamine maleate sustained-release pellets and the preparation process thereof according to claim 8, wherein the wax refining and stirring device comprises: the top fixed connection main part (1) of cover axle (63), sliding connection has slide shaft (64) on cover axle (63), be connected with telescopic link (69c) between slide shaft (64) and cover axle (63), telescopic link (69c) drive slide shaft (64) slide along cover axle (63), fixedly connected with fourth gear (65) and fifth gear (66) on slide shaft (64).
10. The wax refining and stirring device for the Paracetamol, Pericarppium Oxycoccum and Paracetamol, and the preparation process thereof according to claim 9, is characterized in that: fixedly connected with connecting rod (67) on second pivot (62), the both ends of connecting rod (67) are rotated respectively and are connected with third pivot (68), the bottom fixedly connected with stirring frame (69b) of third pivot (68), the top fixedly connected with sixth gear (69) and seventh gear (69a) of third pivot (68), fifth gear (66) and seventh gear (69a) meshing.
S1: when the main body 1 is used for stirring operation, firstly, the main body 1 is moved to a required use position through the supporting mechanism 2, and the adding and discharging ports of the in-out mechanism 3 are aligned to upstream and downstream equipment to complete preparation work;
s2: then starting the adjustment mechanism 4 to close and open a corresponding channel, starting the conveying mechanism 5, adding the materials to the vicinity of the conveying mechanism 5 through the in-out mechanism 3, and conveying the materials to the inside of the main body 1 by the conveying mechanism 5 in a relay manner, so that the materials are stirred in the closed main body 1, thereby avoiding the sharp odor from overflowing and improving the quality of the medicines;
s3: and finally, the stirring mechanism 6 is started, the stirring assembly inside the stirring mechanism 6 rotates when the tool is used, the stirring effect is greatly improved, the stirring speed can be adjusted conveniently according to different materials by adjusting the stirring speed, the use flexibility of the equipment is improved, after the stirring is finished, the adjusting mechanism 4 is operated to open and close corresponding channels, the conveying mechanism 6 runs in the reverse direction again, and the discharging process is completed.
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CN202111417455.XA CN114160013B (en) | 2021-11-26 | 2021-11-26 | Waxy refining stirring equipment for sustained-release amikacin pellets and preparation process thereof |
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CN202111417455.XA CN114160013B (en) | 2021-11-26 | 2021-11-26 | Waxy refining stirring equipment for sustained-release amikacin pellets and preparation process thereof |
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Citations (2)
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CN106120204A (en) * | 2015-07-27 | 2016-11-16 | 海宁杰特玻纤布业有限公司 | The glass fiber yarn coating apparatus of drive mechanism |
CN111778668A (en) * | 2020-07-10 | 2020-10-16 | 陈旭亮 | Printing and dyeing equipment storage hopper convenient to add material |
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Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106120204A (en) * | 2015-07-27 | 2016-11-16 | 海宁杰特玻纤布业有限公司 | The glass fiber yarn coating apparatus of drive mechanism |
CN111778668A (en) * | 2020-07-10 | 2020-10-16 | 陈旭亮 | Printing and dyeing equipment storage hopper convenient to add material |
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