CN114159105A - Continuous low-temperature biopsy safety gas supply system and low-temperature biopsy device - Google Patents

Continuous low-temperature biopsy safety gas supply system and low-temperature biopsy device Download PDF

Info

Publication number
CN114159105A
CN114159105A CN202210042223.9A CN202210042223A CN114159105A CN 114159105 A CN114159105 A CN 114159105A CN 202210042223 A CN202210042223 A CN 202210042223A CN 114159105 A CN114159105 A CN 114159105A
Authority
CN
China
Prior art keywords
temperature
low
valve
gas
flow equalizing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202210042223.9A
Other languages
Chinese (zh)
Inventor
李晨光
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Saien Medical Technology Lianyungang Co ltd
Original Assignee
Shanghai Lisheng Medical Technology Co ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Lisheng Medical Technology Co ltd filed Critical Shanghai Lisheng Medical Technology Co ltd
Priority to CN202210042223.9A priority Critical patent/CN114159105A/en
Publication of CN114159105A publication Critical patent/CN114159105A/en
Pending legal-status Critical Current

Links

Images

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0266Pointed or sharp biopsy instruments means for severing sample
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B10/00Other methods or instruments for diagnosis, e.g. instruments for taking a cell sample, for biopsy, for vaccination diagnosis; Sex determination; Ovulation-period determination; Throat striking implements
    • A61B10/02Instruments for taking cell samples or for biopsy
    • A61B10/0233Pointed or sharp biopsy instruments
    • A61B10/0283Pointed or sharp biopsy instruments with vacuum aspiration, e.g. caused by retractable plunger or by connected syringe
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00333Breast
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577Ablation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636Sensing and controlling the application of energy
    • A61B2018/00696Controlled or regulated parameters
    • A61B2018/00744Fluid flow
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00964Features of probes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0231Characteristics of handpieces or probes
    • A61B2018/0262Characteristics of handpieces or probes using a circulating cryogenic fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/02Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques
    • A61B2018/0293Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by cooling, e.g. cryogenic techniques using an instrument interstitially inserted into the body, e.g. needle

Abstract

The application relates to a continuous low-temperature biopsy safety gas supply system and a low-temperature biopsy device, which comprise a low-temperature resistant gas pipe connected between a compressed gas tank and an adhesion probe, and are used for directly connecting compressed cooling gas of the compressed gas tank into the adhesion probe; the flow equalizing valve device is arranged on the low-temperature-resistant air pipe and used for equalizing the flow of the compressed cooling gas; and the electronic valve is arranged on the low-temperature-resistant air pipe and is used for opening and closing the low-temperature-resistant air pipe under the control of a computer control system. The low-temperature-resistant air pipe is used for directly connecting compressed cooling gas into the adhesion probe, so that the cost of a valve body is saved, the complexity of a pipeline system can be reduced, and the situation that the cooling gas cannot continuously enter the adhesion probe due to the fact that a main valve is closed in the process that a nut pushes a cam to drive a valve rod is avoided. The low-temperature using condition in the biopsy process is continuously kept through the control of a low-temperature resistant trachea, a flow equalizing valve device, an electronic valve and a computer.

Description

Continuous low-temperature biopsy safety gas supply system and low-temperature biopsy device
Technical Field
The application relates to the technical field of pneumatic control, in particular to a continuous low-temperature biopsy safety gas supply system and a low-temperature biopsy device.
Background
The vacuum assisted biopsy system advocated by biopsy involves suctioning a breast lesion into a cannula and shearing off the edge of the suctioned lesion to obtain a biopsy sample. The device utilizes vacuum atherectomy to cut and collect tissue to the side of an open tubular device, in which the rotary coring device slides. In order to ensure the integrity of the cut tissue, a freezing rotary cutting method is often used, but the freezing temperature of the human body cells needs to be controlled because the human body cells are frozen to cause certain damage.
In the patent with publication No. CN100571649C, a rotary core biopsy device with liquid refrigerant adhesion probe is provided, such as the pneumatic system shown in fig. 1, which uses a screw rod driven by a motor and a matched nut 31 as driving elements, and uses a driving cylinder to release gas to cool the adhesion cooling probe in the biopsy instrument and drive a cutting sleeve to rotate back and forth by driving a set retraction valve 46 (corresponding to a cylinder 50), a main valve 41 (corresponding to a cylinder 45) and an advance valve 51 (corresponding to a cylinder 55); the right end 30 of the nut 31 directly acts on the main valve 41, and after the nut is opened, the cooling gas of the compressed gas tank enters the main valve 41 through the input pipe 44 and is further conveyed into the needle pipe with the probe attached through the output pipe 43, so that the probe is cooled; two cams 32 and 33 driven by the left end 30 of the nut 31 respectively drive the valve rod 52 and the valve rod 57 as the opening and closing members of the advancing valve 51 and the retracting valve 46, so as to realize the advancing rotary cutting of the cutting cannula and the retracting action after sampling. The method has the following technical problems:
the opening and closing of the main valve 41 is driven by the rightward movement of the right end of the nut 31, and the cylinder 45 is opened to allow the cooling gas to enter, and then the cooling gas is delivered to the adhesion cooling probe through the delivery pipe 43 to cool the adhesion cooling probe. When the cooling time is reached, the nut 31 moves to the left, the main valve 41 cylinder is closed first, the puncture is ready for biopsy sampling, and at the stage that the nut 31 moves to the left to push the cam 32 to open the advancing valve 51 to drive the cutting cannula to rotate in a rotating way, the probe can not be cooled by the cooling gas at the initial temperature any more, and the heat conduction of the device causes the temperature of the puncture section of the probe to gradually rise, so that the temperature requirement required by the biopsy is lost. Therefore, the main valve 41 does not function much at this time, and is redundant.
Disclosure of Invention
In view of the above, the present application proposes a continuous cryobiopsy safety gas supply system and a cryobiopsy device, which solve the problems of the prior art.
The first aspect of this application provides a security air supply system of continuation low temperature biopsy, including the screw rod, with the supporting nut of screw rod, a pair of drive cam, a pair of drive valve rod, the valve that contracts, advance the valve, compress gas jar and adhere to the probe, still include:
the low-temperature-resistant gas pipe is connected between the compressed gas tank and the adhesion probe and is used for directly connecting compressed cooling gas of the compressed gas tank into the adhesion probe;
the flow equalizing valve device is arranged on the low-temperature-resistant air pipe and used for performing flow equalizing treatment on the input compressed cooling gas and outputting the compressed cooling gas with uniform speed;
the electronic valve is arranged on the low-temperature-resistant air pipe on one side of the output end and/or the input end of the flow equalizing valve device and is used for opening and closing the low-temperature-resistant air pipe under the control of a computer control system;
the printed circuit board is provided with a computer control system and is used for carrying out time sequence control on the opening and closing of the electronic valve;
the electronic valve is electrically connected to the printed circuit board.
As an optional embodiment of the present application, optionally, the flow equalizing valve device comprises:
the detachable shell is provided with an inlet end used for connecting the input end of the low temperature resistant air pipe and an outlet end used for connecting the output end of the low temperature resistant air pipe;
the flow equalizing inner core is fixedly arranged in the detachable shell, and an airflow channel communicated with the outlet end is reserved between the flow equalizing inner core and the detachable shell;
and the buffer cavity is arranged in the flow equalizing inner core in a centrosymmetric manner and is communicated with the input end and the airflow channel.
As an optional embodiment of the present application, optionally, the flow equalizing inner core is a solid of revolution structure, and a cross section of the flow equalizing inner core is trapezoidal; the cavity surface of the buffer cavity is a circular arc surface.
As an optional embodiment of the present application, optionally, the flow equalizing valve device further comprises:
the centers of the two mounting holes are symmetrically arranged on the left end surface and the right end surface of the flow equalizing inner core;
the sealing gasket is hermetically arranged between the right end surface of the flow equalizing inner core and the inner side surface of the detachable shell, and is provided with a central hole for the input end to pass through;
and the at least one pair of bolt assemblies are used for fixing the sealing gasket between the right end surface of the flow equalizing inner core and the inner side surface of the detachable shell.
As an optional embodiment of the present application, optionally, the flow equalizing valve device further comprises:
the low temperature resistant plate is fixed on the left end surface of the flow equalizing inner core through the bolt assembly;
the temperature detection chip is arranged inside the low temperature resistant plate and is electrically connected with the printed circuit board; the temperature detection chip is used for detecting the temperature of the air flow after the air flow is equalized by the equalizing inner core in real time and sending the temperature to the computer control system.
As an optional embodiment of the present application, optionally, the flow equalizing valve device further comprises:
and the input end and the output end of the low-temperature resistant air pipe are respectively matched in the elastic sealing rings.
As an optional embodiment of the present application, optionally, the method further includes:
the flow meter is arranged on the low-temperature-resistant gas pipe on one side of the flow valve device and/or the electronic valve and is electrically connected with the printed circuit board; the flow meter is used for detecting the flow rate of the cooling gas passing through the low-temperature-resistant gas pipe in real time and sending the flow rate to the computer control system.
A second aspect of the present application provides a cryobiopsy device comprising a housing, further comprising:
the continuous low-temperature biopsy safety gas supply system is arranged on the shell;
a biopsy instrument sealingly fitted within the mounting cavity of the housing;
the valve is arranged on the shell and used for shunting cooling gas of the continuous low-temperature biopsy safety gas supply system and respectively providing pneumatic power for the retraction valve and the advance valve;
the cutting sleeve is in sealing fit with the inside of the cutting sleeve, and rotary-cut sampling is realized through the control of the retraction valve and the advancing valve;
and an adhesion probe coaxially fitted in the cutting cannula and cooled by compressed cooling gas delivered through the low temperature resistant gas pipe 101.
As an optional embodiment of the present application, optionally, the method further includes:
the tank is fixedly arranged on the shell, and the compressed gas tank is matched in the tank;
a pierce pin connector provided at a passage between the canister and the valve block, a gas outlet of the compressed gas tank being fitted on the pierce pin connector; piercing a gas outlet of the compressed gas tank through the pierce pin connector when the compressed gas tank is fitted within the canister, delivering compressed cooling gas through the low temperature resistant gas tube to a valve.
As an optional embodiment of the present application, optionally, the method further includes:
the air inlet is arranged on the biopsy instrument, and the low-temperature-resistant air pipe is connected between the compressed air tank and the air inlet;
and the pipeline is connected between the air inlet hole and the adhesion probe.
The technical effects of this application:
the application includes: the low-temperature-resistant gas pipe is connected between the compressed gas tank and the adhesion probe and is used for directly connecting compressed cooling gas of the compressed gas tank into the adhesion probe; the flow equalizing valve device is arranged on the low-temperature-resistant air pipe and used for performing flow equalizing treatment on the input compressed cooling gas and outputting the compressed cooling gas with uniform speed; the electronic valve is arranged on the low-temperature-resistant air pipe on one side of the output end and/or the input end of the flow equalizing valve device and is used for opening and closing the low-temperature-resistant air pipe under the control of a computer control system; the printed circuit board is provided with a computer control system and is used for carrying out time sequence control on the opening and closing of the electronic valve; the electronic valve is electrically connected to the printed circuit board. The compressed cooling gas of the compressed gas tank is directly connected into the adhesion probe through the low-temperature-resistant gas pipe, so that the cost of a valve body is saved, the complexity of a pipeline system can be reduced, and the situation that the cooling gas cannot continuously enter the adhesion probe due to the fact that the main valve is closed in the process that the nut pushes the cam to drive the valve rod is avoided. Through the low temperature resistant trachea, flow equalizing valve device, electronic valve and computer control, can continuously carry out cryogenic cooling to the probe, keep the low temperature service condition in the biopsy process.
Drawings
The accompanying drawings, which are incorporated in and constitute a part of this specification, illustrate exemplary embodiments, features, and aspects of the application and, together with the description, serve to explain the principles of the application.
FIG. 1 is a schematic diagram of a prior art pneumatic system configuration;
FIG. 2 shows a schematic diagram of the pneumatic system components of the present application;
FIG. 3 is a schematic cross-sectional structural view of the flow equalizing valve apparatus of the present application;
FIG. 4 shows a schematic cross-sectional structural view of a cryobiopsy device of the present application.
Detailed Description
Various exemplary embodiments, features and aspects of the present application will be described in detail below with reference to the accompanying drawings. In the drawings, like reference numbers can indicate functionally identical or similar elements. While the various aspects of the embodiments are presented in drawings, the drawings are not necessarily drawn to scale unless specifically indicated.
It will be understood, however, that the terms "central," "longitudinal," "lateral," "length," "width," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in an orientation or positional relationship indicated in the drawings for convenience in describing or simplifying the description, and do not indicate or imply that the device or element so referred to must have a particular orientation, be constructed and operated in a particular orientation, and thus should not be considered as limiting the invention.
Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include one or more of that feature. In the description of the present invention, "a plurality" means two or more unless specifically defined otherwise.
The word "exemplary" is used exclusively herein to mean "serving as an example, embodiment, or illustration. Any embodiment described herein as "exemplary" is not necessarily to be construed as preferred or advantageous over other embodiments.
Furthermore, in the following detailed description, numerous specific details are set forth in order to provide a better understanding of the present application. It will be understood by those skilled in the art that the present application may be practiced without some of these specific details. In some instances, methods, means, elements and circuits that are well known to those skilled in the art have not been described in detail so as not to obscure the present application.
Example 1
This application is through low temperature resistant trachea with the compressed cooling gas direct access of compressed gas jar adhere to the probe, not only save the cost of a main valve body, can also reduce pipe-line system's complexity for at the nut promote the cam and drive the in-process of valve rod, the main valve can not appear and close and lead to the unable condition that continuously gets into the adhesion probe of cooling gas to take place. Through the low temperature resistant trachea, flow equalizing valve device, electronic valve and computer control, can continuously carry out cryogenic cooling to the probe, keep the low temperature service condition in the biopsy process.
As shown in fig. 2, a first aspect of an embodiment of the present application provides a continuous cryobiopsy safety gas supply system, which includes a screw, a nut 31 mated with the screw, a pair of driving cams, a pair of driving valve rods, a retraction valve 46, an advance valve 51, a compressed gas tank, and an adhesion probe. In fig. 1, the screw drives the nut 31 to move left and right; in the present embodiment, as shown in fig. 2, the main valve 41 is removed, and the cam 32 and the cam 33 are pushed in sequence only by the nut 31 to open and close the advancing valve 51 and the retracting valve 46, respectively, see the embodiment described in the patent document with the publication number CN100571649C, and the details are not repeated here.
The contact surface between the cam and the nut 31 is an arc-shaped surface, even if the nut 31 moves leftwards at a constant speed, because the stroke of the arc-shaped surface is larger than that of the contact surface of the valve rod, and because the distance between the two ends of the cam and the central point is not limited, the pushing speed of the other end of the cam to the valve rod is not close to the constant speed due to the contact movement between the cam and the arc-shaped surface. This causes the speed of opening the valve of the valve body to be different at the right end of the valve rod, and also causes the uneven air flow inside the valve body.
In the patent scheme of the background art, the relative motion between two cams and corresponding valve rods is pushed by directly contacting the tail ends of the valve rods through the circular arc surfaces of the wheel, and the circular arc motion tracks are point-to-surface. In the process of the rotary cutting, the two do not keep the motion with stable speed, so that the motion speed of the valve rod is inconsistent, the excitation force of the compressed cooling gas in the corresponding cylinder to a driving part such as a cutting sleeve is different when the compressed cooling gas is output, and the rotary cutting and sampling can damage focus tissue cells and even influence the tissue structure of other parts of the focus, thereby causing pain.
In order to maintain the relative uniform movement between the nut 31 and the cam, in the present embodiment, as shown in fig. 2, the contact surface of the cam 32 is designed as the contact surface 32a parallel to the pushing surface of the nut 31, and the contact surface of the cam 33 is designed as the contact surface 33a parallel to the pushing surface of the nut 31, so that the contact surfaces 32a and 33a maintain the tangential contact movement with the pushing surface of the nut 31, and the relative movement of surface-to-surface contact makes the nut pushing cam more stable.
The system further comprises:
a low temperature resistant gas pipe 101 connected between the compressed gas tank and the adhesion probe for directly connecting the compressed cooling gas of the compressed gas tank to the adhesion probe; in the above-mentioned patent publication, the cooling gas in the compressed gas tank enters the main valve 41 through the inlet 44, and in the process that the nut 31 pushes the cam to drive the valve stem, the main valve 41 is closed, and the cooling gas cannot continuously enter the adhesion probe, and the probe cannot continuously be cooled. Therefore, in the embodiment, the main valve is omitted, and the compressed cooling gas in the compressed gas tank is directly connected to the attachment probe through the low-temperature-resistant gas pipe 101, so that the cost of a valve body is saved, the complexity of a pipeline system can be reduced, and the situation that the cooling gas cannot continuously enter the attachment probe due to the fact that the main valve is closed in the process that the nut pushes the cam to drive the valve rod is avoided. Of course, as shown in fig. 4, there is still a valve to divert the cooling gas output from the output end of the low temperature resistant gas pipe, and a part of the cooling gas is directly delivered to the adhesion probe through a pipeline. The material of the low temperature resistant gas pipe 101 is a material resistant to a low temperature of minus 30 to 70 ℃, and is not limited in this place.
The flow equalizing valve device 102 is arranged on the low-temperature-resistant air pipe and is used for performing flow equalizing treatment on input compressed cooling gas and outputting uniform-speed compressed cooling gas; the flow valve device 102 homogenizes the high-speed airflow from the compressed air tank and outputs a low-speed and uniform cooling airflow.
The electronic valve 103 is arranged on the low-temperature-resistant air pipe on one side of the output end and/or the input end of the flow equalizing valve device and is used for opening and closing the low-temperature-resistant air pipe under the control of a computer control system; the electronic valve 103 is used for controlling the opening and closing of the circulation of the low-temperature-resistant air pipe, and the sequential logic control or manual control is performed through a computer control system. And in the process that the valve rod is driven by the cam to open the advancing valve, the low-temperature-resistant air pipe is continuously controlled to be opened, so that the attached probe is continuously cooled at low temperature in the process of cutting the sleeve to perform low-temperature sampling.
The printed circuit board 14 is provided with a computer control system and is used for carrying out time sequence control on the opening and closing of the electronic valve; the electronic valve is electrically connected to the printed circuit board.
As an alternative embodiment of the present application, as shown in fig. 3, optionally, the flow equalizing valve device comprises:
a detachable shell 202, on which an inlet end for connecting the input end 207 of the low temperature resistant gas pipe 101 and an outlet end for connecting the output end 200 of the low temperature resistant gas pipe 101 are arranged; the detachable shell 202 is a conical shell, is hollow inside, and is a detachable shell structure, and the specific detachable mode is not limited, but needs to be sealed, and the inner side surface can be sealed by sealing paint and the like, and the specific sealing is not limited. The left end and the right end of the detachable shell 202 are respectively provided with an inlet end for connecting the input end 207 of the low temperature resistant air pipe 101 and an outlet end for connecting the output end 200 of the low temperature resistant air pipe 101.
The flow equalizing inner core 203 is fixedly arranged in the shell of the detachable shell 202, and an airflow channel communicated with the outlet end is reserved between the flow equalizing inner core and the detachable shell 202; the flow equalizing inner core 203 is used for buffering and homogenizing low-temperature cooling gas which is excited to be input, so that the exploded gas flow is mixed and filled to obtain a mild and low-speed gas flow, the right end face of the flow equalizing inner core 203 is fixed on the right side face inside the detachable shell 202 in a sealing mode, and the bolt assembly extends into the flow equalizing inner core 203 from outside to fix the flow equalizing inner core 203.
And the buffer cavity 204 is arranged in the flow equalizing inner core 203 in a centrosymmetric manner and communicates the input end 207 with the airflow channel. The buffer cavity 204 is a cavity with an arc cross section, high-speed airflow enters the buffer cavity 204 to be buffered for the first time, and then enters the space of the airflow channel to be buffered for the second time, and the space of the buffered airflow is larger than the space of the air inlet end.
As an optional embodiment of the present application, optionally, the flow equalizing inner core 203 is a solid of revolution structure, and its cross section is trapezoidal; the cavity surface of the buffer cavity 204 is a circular arc surface. As shown in fig. 3, the cross section of the buffer cavity 204 is an arc surface, the overall structure is an arc segment structure, 3 buffer cavities are symmetrically arranged in the inner portion of the flow equalizing inner core 203, and the right end of each buffer cavity is communicated with the right end face of the flow equalizing inner core 203.
As an optional embodiment of the present application, optionally, the flow equalizing valve device further comprises:
the centers of the two mounting holes are symmetrically arranged on the left end surface and the right end surface of the flow equalizing inner core 203;
the sealing gasket 205 is arranged between the right end surface of the flow equalizing inner core 203 and the inner side surface of the detachable shell 202 in a sealing way, and is provided with a central hole for the input end 207 to pass through;
at least one pair of bolt assemblies is used for fixing the sealing gasket 205 between the right end face of the flow equalizing inner core 203 and the inner side face of the detachable outer shell 202.
The mounting holes are formed in the left end face and the right end face of the flow equalizing inner core 203, and the centers of the flow equalizing inner cores are symmetrically three. And the sealing gasket 205 is clamped between the right end surface of the flow equalizing inner core 203 and the inner side surface of the detachable shell 202 and is sealed and fixed through a bolt assembly.
As an optional embodiment of the present application, optionally, the flow equalizing valve device further comprises:
the low temperature resistant plate 201 is fixed on the left end face of the flow equalizing inner core 203 through the bolt assembly;
the temperature detection chip is arranged inside the low temperature resistant plate 201 and is electrically connected with the printed circuit board; the temperature detection chip is used for detecting the temperature of the air flow after the air flow is equalized by the equalizing inner core 203 in real time and sending the temperature to the computer control system.
As shown in fig. 3, when the low-temperature gas after the uniform velocity reaches the airflow channel on the left side of the flow equalizing inner core 203, the temperature is detected, so that a low-temperature resistant plate 201 is fixed on the left end surface of the flow equalizing inner core 203, and in order to improve the stability of the left portion of the flow equalizing inner core 203, the low-temperature resistant plate 201 is fixed on the left end surface of the flow equalizing inner core 203 after entering from the outer side of the detachable outer shell 202 and passing through the airflow channel through a bolt assembly. The temperature detection chip is arranged inside the low temperature resistant board 201 and electrically connected with the printed circuit board, and can detect the temperature of the air flow in the space.
As an optional embodiment of the present application, optionally, the flow equalizing valve device further comprises:
a pair of elastic sealing rings 206 respectively fitted at the inlet end and the outlet end of the detachable housing 202, wherein the input end 207 and the output end 200 of the low temperature resistant gas pipe 101 are respectively fitted in the elastic sealing rings 206.
And the elastic sealing ring 206 is screwed at the input end 207 and the output end 200 of the low temperature resistant gas pipe 101, is a port connecting piece consisting of a screw sleeve and the elastic sealing ring, and is used for connecting the input end 207 and the output end 200 of the low temperature resistant gas pipe 101. The elastic sealing rings 206 are respectively fitted at the inlet end and the outlet end of the removable housing 202.
As an optional embodiment of the present application, optionally, the method further includes:
a flow meter 104, which is disposed on the low temperature resistant gas pipe 101 on one side of the flow valve device 102 and/or the electronic valve 103, and is electrically connected to the printed circuit board; the flow meter 104 is used for detecting the flow rate of the cooling gas passing through the low temperature resistant gas pipe 101 in real time and sending the flow rate to a computer control system.
The flow rate meter 104, which is provided in this embodiment on the low temperature resistant gas pipe 101 on one side of the electronic valve 103, is configured to detect the flow rate of the cooling gas passing through the low temperature resistant gas pipe 101 in real time, and send the flow rate to the computer control system.
Example 2
This embodiment is used for cryobiopsy needle with above-mentioned continuation cryobiopsy safety gas supply system on, upgrades, reforms its technical scheme, reduces the use of main valve, saves economic cost, provides sustainable cryogenic cooling gas for the probe continuously keeps good low temperature result of use.
As shown in fig. 4, a second aspect of the present application provides a cryogenic biopsy device comprising a housing 1, further comprising:
the continuous low-temperature biopsy safety gas supply system is arranged on the shell;
a biopsy instrument 16 sealingly fitted within the mounting cavity of the housing;
the valve 6 is arranged on the shell and used for shunting cooling gas of the continuous low-temperature biopsy safety gas supply system and respectively providing pneumatic power for the retraction valve 46 and the advance valve 51;
a cutting sleeve 17 which is hermetically fitted in the cutting sleeve and is rotationally cut and sampled by the control of the retraction valve 46 and the advance valve 51;
and an adhesion probe coaxially fitted in the cutting cannula and cooled by compressed cooling gas delivered through the low temperature resistant gas pipe 101.
As an optional embodiment of the present application, optionally, the method further includes:
the tank 5 is fixedly arranged on the shell, and the compressed gas tank is matched in the tank;
a pierce pin connector 4 provided at a passage between the canister and the valve block, a gas outlet of the compressed gas tank being fitted on the pierce pin connector; when the compressed gas tank is fitted into the canister, a gas outlet of the compressed gas tank is pierced by the piercing pin connector, and compressed cooling gas is delivered to a valve through the low temperature resistant gas pipe 101.
As shown in fig. 4, after one main valve is omitted, the compressed cooling gas is delivered to the valve 6 through the low temperature resistant gas pipe 101, and then distributed, a part of the compressed cooling gas directly flows to the adhesion probe through one pipeline, and the other compressed cooling gas is distributed to the advancing valve and the retracting valve, and the corresponding configuration of the pipeline is changed, which is not described in detail herein, and the pipeline is distributed by the user according to the saving distribution principle.
As an optional embodiment of the present application, optionally, the method further includes:
the air inlet is arranged on the biopsy instrument, and the low-temperature-resistant air pipe 101 is connected between the compressed air tank and the air inlet;
and the pipeline is connected between the air inlet hole and the adhesion probe.
Having described embodiments of the present application, the foregoing description is intended to be exemplary, not exhaustive, and not limited to the disclosed embodiments. Many modifications and variations will be apparent to those of ordinary skill in the art without departing from the scope and spirit of the described embodiments. The terminology used herein is chosen in order to best explain the principles of the embodiments, the practical application, or improvements made to the technology in the marketplace, or to enable others of ordinary skill in the art to understand the embodiments disclosed herein.

Claims (10)

1. The utility model provides a security air feed system of lasting low temperature biopsy, includes the screw rod, with the supporting nut of screw rod, a pair of drive cam, a pair of drive valve rod, retraction valve, advancing valve, compressed gas jar and adhesion probe, its characterized in that still includes:
the low-temperature-resistant gas pipe is connected between the compressed gas tank and the adhesion probe and is used for directly connecting compressed cooling gas of the compressed gas tank into the adhesion probe;
the flow equalizing valve device is arranged on the low-temperature-resistant air pipe and used for performing flow equalizing treatment on the input compressed cooling gas and outputting the compressed cooling gas with uniform speed;
the electronic valve is arranged on the low-temperature-resistant air pipe on one side of the output end and/or the input end of the flow equalizing valve device and is used for opening and closing the low-temperature-resistant air pipe under the control of a computer control system;
the printed circuit board is provided with a computer control system and is used for carrying out time sequence control on the opening and closing of the electronic valve;
the electronic valve is electrically connected to the printed circuit board.
2. The continuous cryobiopsy safe gas supply system of claim 1, wherein the flow equalizing valve arrangement comprises:
the detachable shell is provided with an inlet end used for connecting the input end of the low temperature resistant air pipe and an outlet end used for connecting the output end of the low temperature resistant air pipe;
the flow equalizing inner core is fixedly arranged in the detachable shell, and an airflow channel communicated with the outlet end is reserved between the flow equalizing inner core and the detachable shell;
and the buffer cavity is arranged in the flow equalizing inner core in a centrosymmetric manner and is communicated with the input end and the airflow channel.
3. The safe gas supply system for continuous cryobiopsy as claimed in claim 2, wherein the flow equalizing core is a solid of revolution structure with a trapezoidal cross section; the cavity surface of the buffer cavity is a circular arc surface.
4. The continuous cryobiopsy safe gas supply system of claim 2, wherein the flow equalizing valve arrangement further comprises:
the centers of the two mounting holes are symmetrically arranged on the left end surface and the right end surface of the flow equalizing inner core;
the sealing gasket is hermetically arranged between the right end surface of the flow equalizing inner core and the inner side surface of the detachable shell, and is provided with a central hole for the input end to pass through;
and the at least one pair of bolt assemblies are used for fixing the sealing gasket between the right end surface of the flow equalizing inner core and the inner side surface of the detachable shell.
5. The continuous cryobiopsy safe gas supply system of claim 4, wherein the flow equalizing valve arrangement further comprises:
the low temperature resistant plate is fixed on the left end surface of the flow equalizing inner core through the bolt assembly;
the temperature detection chip is arranged inside the low temperature resistant plate and is electrically connected with the printed circuit board; the temperature detection chip is used for detecting the temperature of the air flow after the air flow is equalized by the equalizing inner core in real time and sending the temperature to the computer control system.
6. The continuous cryobiopsy safe gas supply system of claim 2, wherein the flow equalizing valve arrangement further comprises:
and the input end and the output end of the low-temperature resistant air pipe are respectively matched in the elastic sealing rings.
7. The continuous cryobiopsy safe gas supply system of claim 1, further comprising:
the flow meter is arranged on the low-temperature-resistant gas pipe on one side of the flow valve device and/or the electronic valve and is electrically connected with the printed circuit board; the flow meter is used for detecting the flow rate of the cooling gas passing through the low-temperature-resistant gas pipe in real time and sending the flow rate to the computer control system.
8. A cryogenic biopsy device comprising a housing 1, characterized by further comprising:
the continuous cryobiopsy safe gas supply system of any one of claims 1-7, mounted on the housing;
a biopsy instrument sealingly fitted within the mounting cavity of the housing;
the valve is arranged on the shell and used for shunting cooling gas of the continuous low-temperature biopsy safety gas supply system and respectively providing pneumatic power for the retraction valve and the advance valve;
the cutting sleeve is in sealing fit with the inside of the cutting sleeve, and rotary-cut sampling is realized through the control of the retraction valve and the advancing valve;
and the adhesion probe is coaxially matched in the cutting sleeve and is cooled by compressed cooling gas conveyed by the low-temperature-resistant air pipe.
9. The cryogenic biopsy device of claim 8, further comprising:
the tank is fixedly arranged on the shell, and the compressed gas tank is matched in the tank;
a pierce pin connector provided at a passage between the canister and the valve block, a gas outlet of the compressed gas tank being fitted on the pierce pin connector; piercing a gas outlet of the compressed gas tank through the pierce pin connector when the compressed gas tank is fitted within the canister, delivering compressed cooling gas through the low temperature resistant gas tube to a valve.
10. The cryogenic biopsy device of claim 8, further comprising:
the air inlet is arranged on the biopsy instrument, and the low-temperature-resistant air pipe is connected between the compressed air tank and the air inlet;
and the pipeline is connected between the air inlet hole and the adhesion probe.
CN202210042223.9A 2022-01-14 2022-01-14 Continuous low-temperature biopsy safety gas supply system and low-temperature biopsy device Pending CN114159105A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202210042223.9A CN114159105A (en) 2022-01-14 2022-01-14 Continuous low-temperature biopsy safety gas supply system and low-temperature biopsy device

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202210042223.9A CN114159105A (en) 2022-01-14 2022-01-14 Continuous low-temperature biopsy safety gas supply system and low-temperature biopsy device

Publications (1)

Publication Number Publication Date
CN114159105A true CN114159105A (en) 2022-03-11

Family

ID=80489289

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202210042223.9A Pending CN114159105A (en) 2022-01-14 2022-01-14 Continuous low-temperature biopsy safety gas supply system and low-temperature biopsy device

Country Status (1)

Country Link
CN (1) CN114159105A (en)

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020045842A1 (en) * 2000-10-16 2002-04-18 Van Bladel Kevin H. Device for biopsy of tumors
CN101027008A (en) * 2004-02-12 2007-08-29 萨纳鲁斯医疗有限公司 Rotational core biopsy device with liquid cryogen adhesion probe
CN201040139Y (en) * 2007-04-28 2008-03-26 珠海市依科医疗器械有限公司 Pressure reducing stabilizing valve
CN111084658A (en) * 2020-03-23 2020-05-01 上海导向医疗系统有限公司 Freezing adhesion device
US20210000521A1 (en) * 2018-03-02 2021-01-07 The General Hospital Corporation Devices, systems, and methods for cryogenic biopsy sampling
CN215384220U (en) * 2021-05-11 2022-01-04 重庆西山科技股份有限公司 Electrotome biopsy operation device, electrotomy biopsy needle set and vacuum-assisted breast biopsy system

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020045842A1 (en) * 2000-10-16 2002-04-18 Van Bladel Kevin H. Device for biopsy of tumors
CN101027008A (en) * 2004-02-12 2007-08-29 萨纳鲁斯医疗有限公司 Rotational core biopsy device with liquid cryogen adhesion probe
CN201040139Y (en) * 2007-04-28 2008-03-26 珠海市依科医疗器械有限公司 Pressure reducing stabilizing valve
US20210000521A1 (en) * 2018-03-02 2021-01-07 The General Hospital Corporation Devices, systems, and methods for cryogenic biopsy sampling
CN111084658A (en) * 2020-03-23 2020-05-01 上海导向医疗系统有限公司 Freezing adhesion device
CN215384220U (en) * 2021-05-11 2022-01-04 重庆西山科技股份有限公司 Electrotome biopsy operation device, electrotomy biopsy needle set and vacuum-assisted breast biopsy system

Similar Documents

Publication Publication Date Title
US8329476B2 (en) Sample port, multi-layer filter, sampling method, and use of a sample port in sampling
US6551255B2 (en) Device for biopsy of tumors
EP1333759B1 (en) Device for biopsy of tumors
US7402140B2 (en) Rotational core biopsy device with liquid cryogen adhesion probe
WO2007025106A2 (en) Rotational core biopsy device with liquid cryogen adhesion probe
CN109009247B (en) Sampling capsule and sampling capsule system
CN104498350B (en) A kind of homogenizer for separating subcellular components
CN114159105A (en) Continuous low-temperature biopsy safety gas supply system and low-temperature biopsy device
CN209186768U (en) Tissue samples acquisition device and medical instrument
CN204281757U (en) A kind of homogenizer for separating of subcellular components
CN216962516U (en) Needle tip temperature control device and low-temperature biopsy needle
CN211409171U (en) Marrow puncture sampling device
CN209186770U (en) Tissue samples acquisition device and medical instrument
CN117398171A (en) High-efficient cryoablation needle and intelligent control low temperature biopsy device
CN218552379U (en) Cutting force controllable device and frozen biopsy needle
CN217907843U (en) Intelligent control low-temperature biopsy device
CN215129173U (en) Integral type oral mucosa cell sampling kit
CN109124694A (en) A kind of hematology's marrow puncture needle
CN114224399A (en) Intelligent control low-temperature biopsy device
CN210843084U (en) Multipurpose venous blood taking needle
CN217611354U (en) Ablation device and sampling biopsy ablation device
CN103857448B (en) Oxygen concentrator and liquefier system and operational approach thereof
CN218816535U (en) Device for simulating different forms of fractures in coal seam
CN215227913U (en) Power mechanism of sampling device
JPH06167431A (en) Freeze preserving device

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
TA01 Transfer of patent application right

Effective date of registration: 20231122

Address after: 222069 China (Jiangsu) Pilot Free Trade Zone Lianyungang Area Economic and Technological Development Zone, Lianyungang City, Jiangsu Province, China (Jiangsu)

Applicant after: Saien Medical Technology (Lianyungang) Co.,Ltd.

Address before: 201499 room 716, building 10, No. 2168, Chenhang highway, Minhang District, Shanghai

Applicant before: Shanghai Lisheng Medical Technology Co.,Ltd.

TA01 Transfer of patent application right