CN114127092A - 人乳头瘤病毒多价免疫原性组合物 - Google Patents
人乳头瘤病毒多价免疫原性组合物 Download PDFInfo
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- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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- C12N2710/00011—Details
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- C12N2710/20034—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Abstract
本发明公开了预防人乳头瘤病毒(HPV)相关疾病或感染的多价HPV免疫原性组合物及其用途。所述多价HPV免疫原性组合物包含：由HPV 6型、11型、16型、18型、31型、33型、45型、52型和58型的L1蛋白组装而成的HPV病毒样颗粒；和一种或多种由其他致病的HPV型别的L1蛋白组装而成的HPV病毒样颗粒。在一个实施方式中，所述一种或多种其他致病的HPV型别选自HPV 35型、39型、51型、56型和59型。在一个实施方式中，至少一种所述HPV病毒样颗粒为嵌合的HPV病毒样颗粒，所述嵌合的HPV病毒样颗粒包含一种或多种嵌合HPV L1蛋白。
Description
PCT国内申请，说明书已公开。
Claims (17)
- PCT国内申请，权利要求书已公开。
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910657255 | 2019-07-19 | ||
| CN2019106572558 | 2019-07-19 | ||
| PCT/CN2020/102601 WO2021013071A1 (zh) | 2019-07-19 | 2020-07-17 | 人乳头瘤病毒多价免疫原性组合物 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN114127092A true CN114127092A (zh) | 2022-03-01 |
| CN114127092B CN114127092B (zh) | 2024-04-16 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202080051322.2A Active CN114127092B (zh) | 2019-07-19 | 2020-07-17 | 人乳头瘤病毒多价免疫原性组合物 |
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| Country | Link |
|---|---|
| US (1) | US20220370590A1 (zh) |
| EP (1) | EP4001298A4 (zh) |
| JP (1) | JP2022540950A (zh) |
| KR (1) | KR20220074855A (zh) |
| CN (1) | CN114127092B (zh) |
| AU (1) | AU2020317321B2 (zh) |
| BR (1) | BR112022001070A2 (zh) |
| CA (1) | CA3147849A1 (zh) |
| MX (1) | MX2022000777A (zh) |
| WO (1) | WO2021013071A1 (zh) |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP4292607A1 (en) * | 2021-01-14 | 2023-12-20 | Sinocelltech Ltd. | Stable preparation of human papillomavirus virus-like particle vaccine |
Citations (6)
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|---|---|---|---|---|
| US5821087A (en) * | 1995-03-30 | 1998-10-13 | Merck & Co., Inc. | Production of recombinant human papillomavirus type II protein utilizing papillomavirus 6/11 hybrid DNA |
| WO2001097840A1 (en) * | 2000-06-21 | 2001-12-27 | Medimmune, Inc. | Chimeric human papillomavirus (hpv) l1 molecules and uses therefor |
| CN102268076A (zh) * | 2010-07-02 | 2011-12-07 | 厦门大学 | 截短的人乳头瘤病毒52型l1蛋白 |
| CN102747047A (zh) * | 2012-02-28 | 2012-10-24 | 厦门大学 | 人乳头瘤病毒型别杂合病毒样颗粒及其制备方法 |
| CN104120088A (zh) * | 2013-04-26 | 2014-10-29 | 北京安百胜生物科技有限公司 | 用汉逊酵母表达系统产生hpv58 l1蛋白的方法 |
| CN106795518A (zh) * | 2014-06-19 | 2017-05-31 | 科罗拉多大学董事会，法人 | 人类乳头瘤病毒构建体 |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2264563T3 (es) | 1994-10-07 | 2007-01-01 | Loyola University Of Chicago | Particulas semejantes al virus del papiloma, proteinas de fusion y procedimiento para su preparacion. |
| CN101518647A (zh) * | 2008-02-29 | 2009-09-02 | 江阴艾托金生物技术有限公司 | 人乳头瘤病毒预防性疫苗、构建方法及应用 |
-
2020
- 2020-07-17 KR KR1020227005633A patent/KR20220074855A/ko unknown
- 2020-07-17 CA CA3147849A patent/CA3147849A1/en active Pending
- 2020-07-17 JP JP2022503540A patent/JP2022540950A/ja active Pending
- 2020-07-17 EP EP20843624.6A patent/EP4001298A4/en active Pending
- 2020-07-17 AU AU2020317321A patent/AU2020317321B2/en active Active
- 2020-07-17 BR BR112022001070A patent/BR112022001070A2/pt active Search and Examination
- 2020-07-17 CN CN202080051322.2A patent/CN114127092B/zh active Active
- 2020-07-17 WO PCT/CN2020/102601 patent/WO2021013071A1/zh unknown
- 2020-07-17 MX MX2022000777A patent/MX2022000777A/es unknown
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2022
- 2022-01-19 US US17/579,459 patent/US20220370590A1/en active Pending
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| US5821087A (en) * | 1995-03-30 | 1998-10-13 | Merck & Co., Inc. | Production of recombinant human papillomavirus type II protein utilizing papillomavirus 6/11 hybrid DNA |
| WO2001097840A1 (en) * | 2000-06-21 | 2001-12-27 | Medimmune, Inc. | Chimeric human papillomavirus (hpv) l1 molecules and uses therefor |
| CN102268076A (zh) * | 2010-07-02 | 2011-12-07 | 厦门大学 | 截短的人乳头瘤病毒52型l1蛋白 |
| CN102747047A (zh) * | 2012-02-28 | 2012-10-24 | 厦门大学 | 人乳头瘤病毒型别杂合病毒样颗粒及其制备方法 |
| CN104120088A (zh) * | 2013-04-26 | 2014-10-29 | 北京安百胜生物科技有限公司 | 用汉逊酵母表达系统产生hpv58 l1蛋白的方法 |
| CN106795518A (zh) * | 2014-06-19 | 2017-05-31 | 科罗拉多大学董事会，法人 | 人类乳头瘤病毒构建体 |
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Also Published As
| Publication number | Publication date |
|---|---|
| BR112022001070A2 (pt) | 2022-04-19 |
| KR20220074855A (ko) | 2022-06-03 |
| AU2020317321A1 (en) | 2022-03-10 |
| CN114127092B (zh) | 2024-04-16 |
| AU2020317321B2 (en) | 2023-07-27 |
| JP2022540950A (ja) | 2022-09-20 |
| CA3147849A1 (en) | 2021-01-28 |
| MX2022000777A (es) | 2022-02-14 |
| WO2021013071A1 (zh) | 2021-01-28 |
| EP4001298A1 (en) | 2022-05-25 |
| EP4001298A4 (en) | 2023-03-15 |
| US20220370590A1 (en) | 2022-11-24 |
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