CN114121331A - 强流电子直线加速器核素制备系统 - Google Patents
强流电子直线加速器核素制备系统 Download PDFInfo
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- CN114121331A CN114121331A CN202111425763.7A CN202111425763A CN114121331A CN 114121331 A CN114121331 A CN 114121331A CN 202111425763 A CN202111425763 A CN 202111425763A CN 114121331 A CN114121331 A CN 114121331A
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- 238000002360 preparation method Methods 0.000 title claims abstract description 22
- 238000010894 electron beam technology Methods 0.000 claims abstract description 19
- 230000008685 targeting Effects 0.000 claims abstract description 18
- 238000009206 nuclear medicine Methods 0.000 claims abstract description 16
- 238000000746 purification Methods 0.000 claims abstract description 13
- 238000000926 separation method Methods 0.000 claims abstract description 13
- 238000004519 manufacturing process Methods 0.000 claims abstract description 10
- 230000005461 Bremsstrahlung Effects 0.000 claims abstract description 9
- 230000002285 radioactive effect Effects 0.000 claims abstract description 9
- 238000006243 chemical reaction Methods 0.000 claims description 46
- 230000005251 gamma ray Effects 0.000 claims description 22
- 239000002184 metal Substances 0.000 claims description 10
- 229910052751 metal Inorganic materials 0.000 claims description 10
- 238000000034 method Methods 0.000 abstract description 3
- 230000005855 radiation Effects 0.000 description 4
- 238000002474 experimental method Methods 0.000 description 3
- 239000002245 particle Substances 0.000 description 3
- 239000003814 drug Substances 0.000 description 2
- 238000012423 maintenance Methods 0.000 description 2
- 238000001816 cooling Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 230000017525 heat dissipation Effects 0.000 description 1
- 238000002844 melting Methods 0.000 description 1
- 230000008018 melting Effects 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
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- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/04—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
- G21G1/12—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by electromagnetic irradiation, e.g. with gamma or X-rays
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- G—PHYSICS
- G21—NUCLEAR PHYSICS; NUCLEAR ENGINEERING
- G21G—CONVERSION OF CHEMICAL ELEMENTS; RADIOACTIVE SOURCES
- G21G1/00—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes
- G21G1/04—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators
- G21G1/06—Arrangements for converting chemical elements by electromagnetic radiation, corpuscular radiation or particle bombardment, e.g. producing radioactive isotopes outside nuclear reactors or particle accelerators by neutron irradiation
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Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111425763.7A CN114121331B (zh) | 2021-11-26 | 2021-11-26 | 强流电子直线加速器核素制备系统 |
DE112021005300.0T DE112021005300T5 (de) | 2021-11-26 | 2021-12-30 | System zur Herstellung von Nukliden mit einem Hochstrom-Elektronen-Linearbeschleuniger |
PCT/CN2021/143018 WO2023092810A1 (zh) | 2021-11-26 | 2021-12-30 | 强流电子直线加速器核素制备系统 |
Applications Claiming Priority (1)
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CN202111425763.7A CN114121331B (zh) | 2021-11-26 | 2021-11-26 | 强流电子直线加速器核素制备系统 |
Publications (2)
Publication Number | Publication Date |
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CN114121331A true CN114121331A (zh) | 2022-03-01 |
CN114121331B CN114121331B (zh) | 2023-02-28 |
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CN202111425763.7A Active CN114121331B (zh) | 2021-11-26 | 2021-11-26 | 强流电子直线加速器核素制备系统 |
Country Status (3)
Country | Link |
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CN (1) | CN114121331B (zh) |
DE (1) | DE112021005300T5 (zh) |
WO (1) | WO2023092810A1 (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116741427A (zh) * | 2022-03-10 | 2023-09-12 | 离子束应用股份有限公司 | 包括弯曲转换器的用于通过轫致辐射生成放射性同位素的系统 |
Citations (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011022454A1 (en) * | 2009-08-18 | 2011-02-24 | Schenter Robert E | Very large enhancements of thermal neutron fluxes resulting in a very large enhancement of the production of molybdenum-99 |
US20110305308A1 (en) * | 2010-06-10 | 2011-12-15 | Fu-Min Su | Advanced once-through processing for extracting molybdenum-99 from deuterium and low enriched uranium solutions |
CN105453187A (zh) * | 2013-05-23 | 2016-03-30 | 加拿大光源公司 | 使用电子束生产钼-99 |
CN110473645A (zh) * | 2019-08-20 | 2019-11-19 | 西安迈斯拓扑科技有限公司 | 基于韧致辐射和光核反应双功能靶的99Mo生产方法及设备 |
CN110706840A (zh) * | 2019-10-18 | 2020-01-17 | 中国科学院合肥物质科学研究院 | 一种基于加速器驱动的99Mo次临界生产装置及方法 |
CN111028973A (zh) * | 2019-12-03 | 2020-04-17 | 成都米纳克企业管理咨询合伙企业(有限合伙) | 一种基于电子加速器的二级辐照生产99Mo的系统及方法 |
CN113470843A (zh) * | 2021-08-02 | 2021-10-01 | 中国原子能科学研究院 | 生产放射性同位素的方法 |
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2021
- 2021-11-26 CN CN202111425763.7A patent/CN114121331B/zh active Active
- 2021-12-30 WO PCT/CN2021/143018 patent/WO2023092810A1/zh active Application Filing
- 2021-12-30 DE DE112021005300.0T patent/DE112021005300T5/de active Pending
Patent Citations (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2011022454A1 (en) * | 2009-08-18 | 2011-02-24 | Schenter Robert E | Very large enhancements of thermal neutron fluxes resulting in a very large enhancement of the production of molybdenum-99 |
US20110129049A1 (en) * | 2009-08-18 | 2011-06-02 | Schenter Robert E | Very large enhancements of thermal neutron fluxes resulting in a very large enhancement of the production of molybdenum-99 |
US20110305308A1 (en) * | 2010-06-10 | 2011-12-15 | Fu-Min Su | Advanced once-through processing for extracting molybdenum-99 from deuterium and low enriched uranium solutions |
CN105453187A (zh) * | 2013-05-23 | 2016-03-30 | 加拿大光源公司 | 使用电子束生产钼-99 |
CN110473645A (zh) * | 2019-08-20 | 2019-11-19 | 西安迈斯拓扑科技有限公司 | 基于韧致辐射和光核反应双功能靶的99Mo生产方法及设备 |
CN110706840A (zh) * | 2019-10-18 | 2020-01-17 | 中国科学院合肥物质科学研究院 | 一种基于加速器驱动的99Mo次临界生产装置及方法 |
CN111028973A (zh) * | 2019-12-03 | 2020-04-17 | 成都米纳克企业管理咨询合伙企业(有限合伙) | 一种基于电子加速器的二级辐照生产99Mo的系统及方法 |
CN113470843A (zh) * | 2021-08-02 | 2021-10-01 | 中国原子能科学研究院 | 生产放射性同位素的方法 |
Non-Patent Citations (4)
Title |
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刘保杰等: "电子直线加速器生产放射性核素~(99)Mo产额的模拟计算", 《中国原子能科学研究院年报》 * |
方锦清: "强流离子束物理问题及其束晕-混沌的控制方法" * |
罗志福等: "用于医用核素钼-99的制备方法", 《同位素》 * |
龙继东,林郁正,罗飞,谷卓伟,石金水: "12MeV强流脉冲电子束对钽靶的破坏研究" * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116741427A (zh) * | 2022-03-10 | 2023-09-12 | 离子束应用股份有限公司 | 包括弯曲转换器的用于通过轫致辐射生成放射性同位素的系统 |
Also Published As
Publication number | Publication date |
---|---|
CN114121331B (zh) | 2023-02-28 |
DE112021005300T5 (de) | 2023-08-31 |
WO2023092810A1 (zh) | 2023-06-01 |
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Effective date of registration: 20250401 Address after: 510000 No. 135 West Xingang Road, Guangdong, Guangzhou Patentee after: SUN YAT-SEN University Country or region after: China Patentee after: Huang Yongsheng Patentee after: Chen Yuan Patentee after: He Yuanqiang Address before: 510275 No. 135 West Xingang Road, Guangdong, Guangzhou Patentee before: SUN YAT-SEN University Country or region before: China |