CN114098747A - Physiological electric signal acquisition system - Google Patents

Physiological electric signal acquisition system Download PDF

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Publication number
CN114098747A
CN114098747A CN202111456301.1A CN202111456301A CN114098747A CN 114098747 A CN114098747 A CN 114098747A CN 202111456301 A CN202111456301 A CN 202111456301A CN 114098747 A CN114098747 A CN 114098747A
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physiological
physiological electric
acquisition
array
mode
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CN202111456301.1A
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Inventor
于文龙
张元康
黄天展
翁恭伟
吴定华
马庆云
梁旭
蓝宝莹
黄品高
王辉
高超
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Shenzhen Runyi Taiyi Technology Co ltd
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Shenzhen Runyi Taiyi Technology Co ltd
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Priority to CN202111456301.1A priority Critical patent/CN114098747A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/08Detecting, measuring or recording devices for evaluating the respiratory organs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/321Accessories or supplementary instruments therefor, e.g. cord hangers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/33Heart-related electrical modalities, e.g. electrocardiography [ECG] specially adapted for cooperation with other devices
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • A61B5/332Portable devices specially adapted therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • A61B5/386Accessories or supplementary instruments therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/389Electromyography [EMG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/398Electrooculography [EOG], e.g. detecting nystagmus; Electroretinography [ERG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/725Details of waveform analysis using specific filters therefor, e.g. Kalman or adaptive filters

Abstract

The embodiment of the application provides a physiological electric signal acquisition system, and the system includes signal input module, at least one collection host computer and client, wherein: the signal input module comprises N signal input electrodes, and the N signal input electrodes are used for acquiring first physiological electric signals of N modes; the acquisition host is respectively connected with the N signal input electrodes in the signal input module and used for receiving the N-modal first physiological electric signals acquired by the signal input module, processing the N-modal first physiological electric signals to obtain N-modal second physiological electric signals and outputting the N-modal second physiological electric signals to the client; and the client is connected with at least one acquisition host and used for displaying the second physiological electric signals in the N modes. The physiological electric signal acquisition system can support multi-mode physiological electric signal acquisition, is convenient to move and carry about, and can be separated from a client side for offline acquisition.

Description

Physiological electric signal acquisition system
Technical Field
The invention relates to the technical field of electronics, in particular to a physiological electric signal acquisition system.
Background
The physiological signals of human body, i.e. various biological indexes in human body, include physiological electrical signals such as electroencephalogram, electrocardio, myoelectricity and the like, and non-electrical signals such as blood oxygen saturation, body temperature, pulse, respiration and the like. From the medical perspective, the physiological electrical signal can directly reflect the fatigue degree and physiological status of the human body, and can become an important index for guiding the adjustment of treatment parameters and clinical medication. Therefore, the detection of physiological electrical signals of the human body plays an important role in contemporary medical and medical research.
Gather human physiology signal of telecommunication at present and accomplish through biological electric signal collection equipment, like the electrocardio monitor, portable brain electricity collection analytic system etc, these equipment are in the actual operation, drop because of leading that is produced by the motion of gathering person and arouse easily that key biological electric signal loses, cause the erroneous judgement of testing result, the physiology signal of telecommunication of collection equipment collection type is single, can't satisfy the demand that multiple type physiology signal of telecommunication of user was gathered, and collection equipment can't break away from the customer end and carry out the work of gathering, the size is huge, heavy, inconvenient removal.
Disclosure of Invention
The embodiment of the invention provides a physiological electric signal acquisition system which can support acquisition of physiological electric signals in various modes, is convenient to move and carry about and can be separated from a client side for off-line acquisition.
The embodiment of the invention provides a physiological electric signal acquisition system, which comprises a signal input module, at least one acquisition host and a client, wherein:
the signal input module comprises N signal input electrodes, wherein the N signal input electrodes are used for collecting first physiological electric signals of N modes, one signal input electrode corresponds to the first physiological electric signal of one mode, and N is an integer greater than or equal to 2;
the at least one acquisition host is respectively connected with N signal input electrodes in the signal input module, and is used for receiving the N-mode first physiological electric signals acquired by the signal input module, processing the N-mode first physiological electric signals to obtain N-mode second physiological electric signals, and outputting the N-mode second physiological electric signals to the client;
the client is connected with the at least one acquisition host and used for displaying the second physiological electric signals in the N modes.
Wherein, gather the host computer and include front end acquisition module, front end acquisition module includes array switch, array filter, array amplifier circuit and array Analog-to-digital converter (ADC), wherein:
the array switch comprises a plurality of switches, and one switch in the plurality of switches is used for controlling the receiving of the first physiological electric signal of the mode;
the array filter comprises a plurality of filters, the array filter is connected with the array switch, and one of the plurality of filters is used for filtering the first physiological electric signal of one mode to obtain a filtered first physiological electric signal of one mode;
the array amplifying circuit comprises a plurality of amplifying circuits, the array amplifying circuit is connected with the array filter, and one of the amplifying circuits is used for amplifying the filtered first physiological electric signal of the one mode to obtain an amplified first physiological electric signal of the one mode;
the array ADC comprises a plurality of ADCs, the array ADC is connected with the array amplifying circuit, and one ADC of the plurality of ADCs is used for converting the amplified first physiological electric signal in one mode into a second physiological electric signal in one mode.
Wherein, gather the host computer and include:
and the data synchronization interface is used for synchronously receiving the first physiological electric signals of the N modes by the at least one acquisition host and synchronously processing the first physiological electric signals of the N modes.
Wherein, gather the host computer and include:
the human-computer interaction interface is used for receiving acquisition parameters configured by the terminal equipment; or sending the running condition of the physiological electric signal acquisition system to the terminal equipment.
Wherein, gather the host computer and include:
and the storage module is used for storing the first physiological electric signals of the N modes acquired by the signal input module in an off-line state.
Wherein, gather the host computer and include:
the main controller comprises an operating system, and is used for controlling the work of the front-end acquisition module, the data synchronization interface, the man-machine interaction interface, the wireless module and the storage module in the acquisition host through the operating system.
Wherein the client is further configured to:
and determining a human body physiological state report by analyzing the signal relation between the second physiological electric signals of each mode in the N modes.
Wherein, gather the host computer and include:
and the wireless module is used for establishing wireless connection with the client and sending the second physiological electric signals of the N types of modes to the client through the established wireless connection.
By implementing the embodiment of the application, the N signal input electrodes of the signal input module are used for acquiring first physiological electrical signals of N modes; the at least one acquisition host is used for receiving the first physiological electrical signals of the N modalities acquired by the signal input module, processing the first physiological electrical signals of the N modalities to obtain second physiological electrical signals of the N modalities, and outputting the second physiological electrical signals of the N modalities to the client; the client is used for displaying the second physiological electric signals of the N modes. Through the physiological electric signal acquisition system, the first physiological electric signals of N types of modes can be synchronously acquired according to user requirements and actual conditions of equipment, the acquisition host is convenient to move and carry about, the acquisition host can be separated from a client to perform offline acquisition, and the acquisition efficiency of the physiological electric signals is improved.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings needed to be used in the description of the embodiments are briefly introduced below, and it is obvious that the drawings in the following description are some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings based on these drawings without creative efforts.
Fig. 1 is a schematic structural diagram of a first embodiment of a physiological electrical signal acquisition system according to the present invention;
fig. 2 is a schematic structural diagram of a front-end acquisition module 200 according to the present invention;
FIG. 3 is a schematic structural diagram of an array switch provided in the present invention;
fig. 4 is a schematic structural diagram of an array filter 400 according to the present invention;
fig. 5 is a schematic structural diagram of an array amplifier circuit 500 according to the present invention;
FIG. 6 is a schematic diagram of a lead dropout detection 600 according to the present invention;
FIG. 7 is a schematic diagram of an active shield driving network 700 according to the present invention;
fig. 8 is a schematic structural diagram of a second embodiment of a physiological electrical signal acquisition system according to the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are some, not all, embodiments of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1, fig. 1 is a schematic structural diagram of a physiological electrical signal acquisition system according to a first embodiment of the present invention.
As shown in the figure, the embodiment of the present invention includes:
the signal input module 101 includes N signal input electrodes, where the N signal input electrodes are used to collect first physiological electrical signals of N modalities, one signal input electrode corresponds to the first physiological electrical signal of one modality, and N is an integer greater than or equal to 2.
In a specific implementation, the signal input module 101 may include N signal input electrodes such as a matrix electrode, a single electrode wire, a standard brain/myoelectric lead expander, an electrocardiographic standard lead, and an electroencephalogram electrode cap. The signal input electrode comprises a plurality of electrodes, the electrodes are used for being in contact with the skin of a human body, and the first physiological electric signal of one mode is acquired. The first physiological electric signals of the N modes are N types of first physiological electric signals, wherein the types of the first physiological electric signals can include N types of electroencephalogram, electrocardio, myoelectricity, electrooculogram, respiration and the like. The signal input module 101 may select a corresponding signal input electrode according to a requirement acquired by a user, for example, if the user needs to acquire a physiological electrical signal of an electroencephalogram, a standard brain/myoelectric lead expander or an electroencephalogram electrode cap may be selected; if the user needs to collect the electrocardio physiological electric signals, the electrocardio standard leads can be selected; if the user needs to collect the myoelectric physiological electric signal, the array electrode can be selected. The plurality of electrodes of the N signal input electrodes in the signal input module 101 are in contact with the skin of the human body, so that the first physiological electrical signals of the N modalities are guided, and the acquisition of the first physiological electrical signals of the N modalities is realized by matching different electrode switching circuits for different signal input electrodes.
At least one collection host 102, including a front-end collection module, respectively connected to the N signal input electrodes in the signal input module, and configured to receive the N-mode first physiological electrical signals collected by the signal input module, process the N-mode first physiological electrical signals to obtain N-mode second physiological electrical signals, and output the N-mode second physiological electrical signals to the client 103.
In a specific implementation, the number of the acquisition hosts is selected by at least one acquisition host 102 according to whether the number of channels of the acquisition host can meet the acquisition requirement of a user, and there are at least the following two deployment situations, specifically as follows:
in case one, there is only one acquisition master. If the user needs to collect the first bioelectrical signal of one modality, one collection host is 64 channels, wherein 10 channels of the 64 channels of one collection host are used as collection channels of the first bioelectrical signal of one modality, only one collection host is needed. If the user needs to collect the first physiological electrical signals of two modalities, one collection host is 64 channels, wherein 10 channels of the 64 channels of one collection host are used as collection channels of the first physiological electrical signals of one modality, and 20 channels of the remaining 54 channels of one collection host are used as collection channels of the first physiological electrical signals of the other modality, only one collection host is needed.
And in case two, two or more acquisition hosts. If a user needs to collect first physiological electrical signals of two modalities, one collection host is 64 channels, wherein 40 channels of the 64 channels of one collection host are used as collection channels of the first physiological electrical signals of one modality, and 40 channels are also needed to be used as collection channels of the first physiological electrical signals of the other modality, but the rest 24 channels of the one collection host cannot meet the collection requirement, so that another collection host needs to be connected, and two collection hosts are needed to use the rest 24 channels of the one collection host and the rest 16 channels of the 64 channels of the other collection host as collection channels of the first physiological electrical signals of the other modality. And the analogy is repeated by more than two acquisition hosts.
The at least one acquisition host 102 is connected with the signal input module 101, so as to receive the first physiological electrical signals in the N modalities, then perform filtering, amplification and analog-to-digital conversion on the first physiological electrical signals to obtain second physiological electrical signals in the N modalities, and output the processed second physiological electrical signals in the N modalities to the client 103.
And the client 103 is connected with the at least one acquisition host 102 and is used for displaying the second physiological electric signals of the N modalities.
In a specific implementation, the client 103 is a device with processing capability and data transceiving capability. The client 103 may generate a sending instruction, a receiving instruction, or a monitoring acquisition process, so as to display the second physiological electrical signals of the N modalities obtained after acquisition and processing. For example, the client 103 may be a Computer, a laptop, a tablet, a palmtop, a desktop, a diagnostic device, a cell phone, an Ultra-mobile Personal Computer (UMPC), a netbook, a Personal Digital Assistant (PDA), or the like.
In the embodiment of the invention, firstly, N signal input electrodes of a signal input module collect first physiological electric signals of N modes; then the acquisition host receives the first physiological electric signals of the N modes acquired by the signal input module, processes the first physiological electric signals of the N modes to obtain second physiological electric signals of the N modes, and outputs the second physiological electric signals of the N modes to the client; and finally, the client displays the second physiological electric signals of the N modes. The physiological electric signal acquisition system can acquire physiological electric signals of multiple modes of a human body, so that the physiological condition of the human body can be known.
Referring to fig. 2, fig. 2 is a schematic structural diagram of a front-end acquisition module 200 according to the present invention. As shown, the circuit in an embodiment of the present invention includes: shielding 201, array switch 202, array filter 203, array amplification circuit 204, array ADC205, lead dropout detection 206, active shield drive network 207, and shielding 208. Wherein:
an output port of the shielding layer 201 is connected with one end of the array switch 202, the ground line of the shielding layer 201 is connected with the ground line of the shielding layer 208 and one end of the resistor R1, the other end of the array switch 202 is connected with an input port of the array filter 203, an output port of the array filter 203 is connected with a first port of the array amplifying circuit 204, a second port of the array amplifying circuit 204 is connected with a first port of the array ADC205, a third port of the array amplifying circuit 204 is connected with a first port of the active shielding driving network 207 and one end of the lead falling detection 206, a second port of the array ADC205 is connected with the other end of the lead falling detection 206, a second port of the active shielding driving network 207 is connected with one end of the resistor R4 and the other end of the resistor R1, and a third port of the active shielding driving network 207 is connected with a non-inverting input end of the operational amplifier, the inverting input end of the operational amplifier is connected with the other end of the resistor R4 and one end of the resistor R2, the output port of the operational amplifier is connected with the other end of the resistor R2 and one end of the resistor R3, and the other end of the resistor R3 is connected with the input port of the shielding layer 208.
In a specific implementation, the array switch 202 includes a plurality of switches, and one of the plurality of switches is used for controlling to receive a first physiological electrical signal of a mode; as shown IN fig. 3, fig. 3 is a schematic structural diagram of an array switch provided by the present invention, IN1P represents a positive switch, IN1N represents a negative switch, IN8P represents another positive switch, IN8N represents another negative switch, and so on for the rest switches. According to different requirements of users, single-ended input and differential input can be configured, and if all negative switches in the switches are closed to serve as common ends of all anodes, the configuration of the single-ended input is completed; if all of the positive and negative switches of the plurality of switches are turned off, the configuration of the differential input is completed. The single-ended input can reduce the number of conducting wires at the input end, and the differential input can better inhibit common-mode signals.
The array filter 203 comprises a plurality of filters, one of which is used for filtering the first bioelectrical signal of the one mode to obtain a filtered first bioelectrical signal of the one mode; as shown in fig. 4, fig. 4 is a schematic structural diagram of an array filter 400 according to the present invention. The array filter 400 includes an Electro-Static discharge (ESD) protection circuit 401 and a plurality of differential low pass filters 402, a port of an IO1 in the ESD protection circuit 401 is connected to one end of an R1 in one differential low pass filter, a port of an IO2 in the ESD protection circuit 401 is connected to one end of an R2 in one differential low pass filter, a port of an IO3 in the ESD protection circuit 401 is connected to one end of an R1 in another differential low pass filter, a port of an IO4 in the ESD protection circuit 401 is connected to one end of an R2 in another differential low pass filter, and so on for the remaining differential low pass filters. In a differential low-pass filter, the other end of R1 and a capacitor CDIFFOne terminal of (1), a capacitor CCM1Is connected to one end of the capacitor C, and the other end of R2 is connected to the capacitor CDIFFAnother terminal of (1), a capacitor CCM2Is connected to a capacitor CCM1The other end of the capacitor C is connected with the ground wireCM2The other end of the second end is connected with the ground wire.In the collecting process, because the electrodes need to be frequently plugged and unplugged, contact type static damage is easily generated, and therefore the electrodes are connected with an ESD protection circuit, and the ESD protection circuit is used for guiding transient overvoltage pulses generated by static electricity into the ground and protecting circuit devices from being damaged by the static electricity. The differential low-pass filter is a first-order low-pass filter consisting of a resistor and a capacitor and used for filtering out-of-band noise and preventing signals outside the Nyquist frequency from aliasing with a first bioelectricity signal of an in-band mode.
The array amplifying circuit 204 includes a plurality of amplifying circuits, and one of the amplifying circuits is configured to amplify the filtered first physiological electrical signal of the one mode to obtain an amplified first physiological electrical signal of the one mode; as shown in fig. 5, fig. 5 is a schematic structural diagram of an array amplifier circuit 500 according to the present invention. In one amplifier circuit of the array amplifier circuit 500, the INP port, the other end of R1 in the one differential filter, and the capacitor CDIFFOne terminal of (1), a capacitor CCM1Is connected with the non-inverting input terminal of the operational amplifier A1, the INN port is connected with the other end of the R2 and the capacitor CDIFFAnother terminal of (1), a capacitor CCM2The one end of operational amplifier a2 is connected with the non-inverting input end of operational amplifier a2, the inverting input end of operational amplifier a1 is connected with the first port of Gain, the output port of operational amplifier a1 is connected with the second port of Gain, the inverting input end of operational amplifier a2 is connected with the third port of Gain, the output port of operational amplifier a2 is connected with the fourth port of Gain, the fifth port of Gain is connected with the first input port of operational amplifier A3, and the sixth port of Gain is connected with the second input port of operational amplifier A3. The array amplifier circuit 204 employs an instrumentation amplifier and a programmable gain, so that the array amplifier circuit has ultra-high input impedance, good Common Mode Rejection Ratio (CMRR), low input offset and low output impedance, and can amplify a first physiological electrical signal of one Mode under a Common Mode voltage.
The array ADC205 comprises a plurality of ADCs, one of which is used to convert the amplified first physiological electrical signal of one modality into a second physiological electrical signal of one modality.
The lead drop detection 206 includes a plurality of lead drop detections, one for detecting in real time whether the electrode is in good contact with the skin of the human body, avoiding the acquisition of the first physiological electrical signal of one modality from being affected by the bad contact of the electrode with the skin. Fig. 6 is a schematic structural diagram of a lead fall-off detection 600 according to the present invention, as shown in fig. 6. In one lead-OUT detection 600, VINP represents the positive pole of the differential input, VINN represents the negative pole of the differential input, VINP is connected to the current source and the first port of the comparator, VINN is connected to the current sink and the second port of the comparator, the OUT1 port of the comparator is connected to the active shield drive network 207, and the OUT2 port of the comparator is connected to the array ADC 205. In the collecting process, the voltage value of the collected first physiological electric signal in the mode is compared with a preset value through the comparator, and whether the electrode falls off or not can be judged. If the electrodes are not in good contact with the skin or fall off, this can result in the path being flooded by the current source or the current, so that the voltage value of the first physiological electrical signal of the one modality approaches the voltage reference of the ADC.
The active shielding driving network 207 is used for removing the common-mode interference signal of the first physiological electrical signal of the one mode. As shown in fig. 7, fig. 7 is a schematic structural diagram of an active shielding driving network 700 according to the present invention. The differentially input positive and negative path signals are added by an operational amplifier, the differential mode signals are cancelled out, and a common mode signal VCOM is left. The obtained common mode signal VCOM is passed through an operational amplifier, and the output SHD is connected to one end of the shielding layer 208. When a certain potential is applied to the shielding layer 208, the interference introduced by the distributed capacitive coupling between the shielding layer 208 and the core will be greatly reduced. And then output after passing through the right leg driving circuit, and the other end of the shielding layer 208 is injected into the human body, so that common mode signals are mutually offset, and the purpose of removing common mode interference signals is achieved.
In the embodiment of the present invention, the array switch 202 may receive the first physiological electrical signal of multiple modalities by closing or opening multiple positive and negative switches; the array filter 203 may be configured to filter the first physiological electrical signals of the multiple modalities to obtain filtered first physiological electrical signals of the multiple modalities; the array amplifying circuit 204 may be configured to amplify the filtered first physiological electrical signal of the multiple modalities to obtain an amplified first physiological electrical signal of the multiple modalities; the array ADC205 may be configured to convert the amplified first physiological electrical signal of the plurality of modalities into a second physiological electrical signal of the plurality of modalities; the lead drop detection 206 can be used to detect whether the electrode is in good contact with the skin of the human body in real time, so as to avoid the influence of the bad contact between the electrode and the skin on the acquisition result of the first physiological electrical signals of the plurality of modes; the active shield drive network 207 may be configured to remove common mode interference signals of the first physiological electrical signal of the plurality of modes. Through the front-end acquisition module 200, physiological electric signals of multiple human modals can be acquired, and the acquisition efficiency of the physiological electric signals is improved.
Referring to fig. 8, fig. 8 is a schematic structural diagram of a physiological electrical signal acquisition system according to a second embodiment of the present invention.
As shown in the figure, the embodiment of the present invention includes:
the signal input module 810 includes N signal input electrodes, where the N signal input electrodes are used to collect first physiological electrical signals of N modalities, one signal input electrode corresponds to the first physiological electrical signal of one modality, and N is an integer greater than or equal to 2.
In a specific implementation, the signal input module 810 may include N signal input electrodes such as a matrix electrode 811, a single electrode wire 812, a standard brain/myoelectric lead expander 813, an electrocardiograph standard lead 814, an electroencephalogram electrode cap 815, and the like, and a transfer interface 816. The plurality of signal input electrodes in the signal input module are selected according to the requirements collected by the user, for example, if the user needs to collect electroencephalogram and electrocardio physiological electric signals, an electroencephalogram electrode cap 815 and an electrocardio standard lead 814 in the signal input module can be selected, wherein the electroencephalogram electrode cap 815 is used for collecting a first electroencephalogram physiological electric signal, and the electrocardio standard lead 814 is used for collecting a first electrocardio physiological electric signal. A plurality of electrodes of N signal input electrodes in the signal input module 810 are in contact with the skin of the human body, and the acquired first physiological electrical signals of N modalities are converted into signals which can be input into the front-end acquisition module 821 of the acquisition host 820 through the adapter 816, wherein one signal input electrode corresponds to one adapter.
The acquisition host 820 includes at least one acquisition host, which is respectively connected to the N signal input electrodes in the signal input module, and is configured to receive the N-mode first physiological electrical signals acquired by the signal input module 810, process the N-mode first physiological electrical signals to obtain N-mode second physiological electrical signals, and output the N-mode second physiological electrical signals to the client 830.
In a specific implementation, the collection host 820 includes: a front-end acquisition module 821, a main controller 822, a man-machine interaction interface 823, a data synchronization interface 824, a wireless module 825 and a storage module 826. Wherein:
the front-end acquisition module 821 is connected to the main controller 822, and the front-end acquisition module 821 obtains second physiological electrical signals of the N modalities by performing filtering, amplification, and analog-to-digital conversion on the acquired first physiological electrical signals of the N modalities by using an array scheme.
The main controller 822 includes an operating system, and the main controller 822 is configured to control the front-end acquisition module 821, the human-computer interaction interface 823, the data synchronization interface 824, the wireless module 825, and the storage module 826 in the acquisition host 820 through the operating system.
Optionally, the main controller 822 may be a single chip microcomputer which is formed by appropriately reducing the frequency and specification of a Central Processing Unit (CPU) and has functions of operation, control, timing, storage, and the like.
The human-computer interaction interface 823 is connected with the main controller 822 and is used for receiving acquisition parameters configured by the terminal equipment; or sending the running condition of the physiological electric signal acquisition system to the terminal equipment.
The terminal device may include a Computer, a notebook Computer, a tablet Computer, a palm top Computer, a desktop Computer, a diagnostic apparatus, a mobile phone, an Ultra-mobile Personal Computer (UMPC), a netbook, a Personal Digital Assistant (PDA), and the like. The main controller 822 receives acquisition parameters configured by the terminal device according to an instruction input by the user through the human-computer interaction interface 823, where the acquisition parameters may include start/stop acquisition, acquisition mode, acquisition channel, sampling rate, amplification factor, and the like. Or, the main controller 822 sends the operation condition of the physiological electrical signal acquisition system to the terminal device through the human-computer interaction interface 823, the terminal device displays the operation condition of the physiological electrical signal acquisition system, and the operation condition of the physiological electrical signal acquisition system may include the acquisition duration of the system, the remaining capacity of the system, the current acquisition state of the system, and the like.
The data synchronization interface 824 is connected to the main controller 822, and is configured to enable the at least one acquisition host to synchronously receive the first physiological electrical signals in the N modalities and synchronously process the first physiological electrical signals in the N modalities.
The data synchronization interface 824 is used for synchronization of a cascade device, which may be another physiological electrical signal acquisition system or another device. If the equipment is another physiological electric signal acquisition system, the equipment can synchronously receive the first physiological electric signals of multiple modes and synchronously process the first physiological electric signals of multiple modes; if the equipment is a stimulator, the stimulator can be synchronized to synchronously induce the starting point and the stimulation pulse of electroencephalogram processing, and a pulse is given to the stimulator while the electroencephalogram signal is intercepted and processed, so that the induced electroencephalogram is automatically obtained.
The wireless module 825 is connected to the main controller 822, and configured to establish a wireless connection with the client, and send the second physiological electrical signals of the N modalities to the client through the established wireless connection.
The storage module 826 is connected to the main controller 822 and is configured to store the first physiological electrical signals of the N modalities acquired by the signal input module offline in an offline state.
In an offline state, the wireless module 825 cannot establish wireless connection with the client, so that the main controller 822 stores the acquired first physiological electrical signals of the N modalities into the storage module 826, and can be separated from the client to perform offline acquisition, so as to ensure that the acquired data is not lost under the condition of an unstable offline state or wireless connection, and meanwhile, the mobile portable acquisition host is convenient to carry.
And the client 830 is connected with the acquisition host 820 and is used for displaying the second physiological electrical signals of the N modalities.
Optionally, the client 830 is further configured to determine a human physiological status report by analyzing a signal relationship between the second physiological electrical signals of each of the N modalities.
In a specific implementation, the client 830 receives the second physiological electrical signals in the N modalities sent by the wireless module 825 in the collection host 820, and displays the second physiological electrical signals in the N modalities. For example, the client receives the second physiological electrical signals of three modalities as follows: the physiological electrocardiosignals, the physiological electroencephalogram signals and the physiological electromyogram signals can determine the relation between the physiological electrocardiosignals and the physiological electroencephalogram signals by analyzing the waveforms and the parameters of the physiological electrocardiosignals and the physiological electroencephalogram signals at a certain same moment, thereby determining the physiological state report of the human body; in addition, if the electroencephalogram physiological electric signals are abnormal within a certain period of time, whether the electrocardio physiological electric signals and the myoelectricity physiological electric signals are also abnormal can be detected, and if the electrocardio physiological electric signals and the myoelectricity physiological electric signals are abnormal, the physiological state of the human body is not good; if the electrocardio-physiological electric signal and the myo-electric physiological electric signal are not abnormal, it is indicated that the reason why the electroencephalogram physiological electric signal is abnormal is other than physiological factors, and the other reasons may include: poor contact between the electrode and the human body, sudden tension of the human body and the like.
In an embodiment of the present invention, the signal input module 810 includes N signal input electrodes, where the N signal input electrodes are used to collect first physiological electrical signals of N modalities, one signal input electrode corresponds to the first physiological electrical signal of one modality, and N is an integer greater than or equal to 2; the acquisition host 820 includes at least one acquisition host, which is respectively connected to N signal input electrodes in the signal input module, and is configured to receive the first physiological electrical signals of the N modalities acquired by the signal input module 810, process the first physiological electrical signals of the N modalities to obtain second physiological electrical signals of the N modalities, and output the second physiological electrical signals of the N modalities to the client 830; the client 830 is configured to display the second physiological electrical signals of the N modalities. Through the physiological electric signal acquisition system, the second physiological electric signals of N types of modes can be synchronously acquired according to user requirements and actual conditions of equipment, the acquisition host 820 is convenient to move and carry about, and can be separated from a client side for offline acquisition, so that the acquisition efficiency of the physiological electric signals is improved.
It should be noted that, for simplicity of description, the above-mentioned embodiments of the method are described as a series of acts or combinations, but those skilled in the art will recognize that the present invention is not limited by the order of acts, as some steps may occur in other orders or concurrently in accordance with the invention. Further, those skilled in the art should also appreciate that the embodiments described in the specification are preferred embodiments and that the acts and modules referred to are not necessarily required by the invention.
In the above embodiments, the descriptions of the respective embodiments have respective emphasis, and for parts that are not described in detail in a certain embodiment, reference may be made to related descriptions of other embodiments.
Those skilled in the art will appreciate that all or part of the steps in the methods of the above embodiments may be implemented by associated hardware instructed by a program, which may be stored in a computer-readable storage medium, and the storage medium may include: flash Memory disks, Read-Only memories (ROMs), Random Access Memories (RAMs), magnetic or optical disks, and the like.
The content downloading method, the related device and the system provided by the embodiment of the present invention are described in detail above, and a specific example is applied in the text to explain the principle and the embodiment of the present invention, and the description of the above embodiment is only used to help understanding the method and the core idea of the present invention; meanwhile, for a person skilled in the art, according to the idea of the present invention, there may be variations in the specific embodiments and the application scope, and in summary, the content of the present specification should not be construed as a limitation to the present invention.

Claims (8)

1. A physiological electrical signal acquisition system, comprising a signal input module, at least one acquisition host and a client, wherein:
the signal input module comprises N signal input electrodes, wherein the N signal input electrodes are used for collecting first physiological electric signals of N modes, one signal input electrode corresponds to the first physiological electric signal of one mode, and N is an integer greater than or equal to 2;
the at least one acquisition host is respectively connected with N signal input electrodes in the signal input module, and is used for receiving the N-mode first physiological electric signals acquired by the signal input module, processing the N-mode first physiological electric signals to obtain N-mode second physiological electric signals, and outputting the N-mode second physiological electric signals to the client;
the client is connected with the at least one acquisition host and used for displaying the second physiological electric signals in the N modes.
2. The system of claim 1, wherein the acquisition host comprises a front-end acquisition module comprising an array switch, an array filter, an array amplification circuit, and an array analog-to-digital converter (ADC), wherein:
the array switch comprises a plurality of switches, and one switch in the plurality of switches is used for controlling the receiving of the first physiological electric signal of the mode;
the array filter comprises a plurality of filters, the array filter is connected with the array switch, and one of the plurality of filters is used for filtering the first physiological electric signal of one mode to obtain a filtered first physiological electric signal of one mode;
the array amplifying circuit comprises a plurality of amplifying circuits, the array amplifying circuit is connected with the array filter, and one of the amplifying circuits is used for amplifying the filtered first physiological electric signal of the one mode to obtain an amplified first physiological electric signal of the one mode;
the array ADC comprises a plurality of ADCs, the array ADC is connected with the array amplifying circuit, and one ADC of the plurality of ADCs is used for converting the amplified first physiological electric signal in one mode into a second physiological electric signal in one mode.
3. The system according to claim 1 or 2, wherein the collection host comprises:
and the data synchronization interface is used for synchronously receiving the first physiological electric signals of the N modes by the at least one acquisition host and synchronously processing the first physiological electric signals of the N modes.
4. The system according to claim 1 or 2, wherein the collection host comprises:
the human-computer interaction interface is used for receiving acquisition parameters configured by the terminal equipment; or sending the running condition of the physiological electric signal acquisition system to the terminal equipment.
5. The system according to claim 1 or 2, wherein the collection host comprises:
and the storage module is used for storing the first physiological electric signals of the N modes acquired by the signal input module in an off-line state.
6. The system according to claim 1 or 2, wherein the collection host comprises:
the main controller comprises an operating system, and is used for controlling the work of the front-end acquisition module, the data synchronization interface, the man-machine interaction interface, the wireless module and the storage module in the acquisition host through the operating system.
7. The system of claim 1 or 2, wherein the client is further configured to:
and determining a human body physiological state report by analyzing the signal relation between the second physiological electric signals of each mode in the N modes.
8. The system according to claim 1 or 2, wherein the collection host comprises:
and the wireless module is used for establishing wireless connection with the client and sending the second physiological electric signals of the N types of modes to the client through the established wireless connection.
CN202111456301.1A 2021-12-01 2021-12-01 Physiological electric signal acquisition system Pending CN114098747A (en)

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