Signal deteching circuit
Technical field
The present invention relates to field of medical technology, and in particular to a kind of signal deteching circuit.
Background technique
Sleep analysis monitor is an important new technology in current sleep medicine, is claimed again in world's sleep study circle
For " goldstandard " for diagnosing sleep disturbance disease, sleep disturbance related diseases various for diagnosis and treatment ensure that health of people is just playing
Increasingly important role.Wherein, electroencephalogram (electroencephalogram, EEG), electrocardiogram
(electrocardiogram, ECG), electroculogram (electro-oculogram, EOG), electromyogram
The acquisition of (electromyography, EMG) is the important evidence of the various sleep disturbance related diseases of diagnosis and treatment, the physiology of high quality
Electrical signal collection is just particularly important.
In order to preferably inhibit Hz noise in electro-physiological signals collection process, the signal-to-noise ratio of electro-physiological signals is improved, is adopted
With differential amplifier circuit, this requires amplifier ins consistent input impedance and signal amplitude, so leading sleep more
The measuring unit of contact impedance is necessary between electrode and skin in monitoring system.
Sleep analysis monitor product on the market all has the function of impedance detection at present, but the measurement of impedance is main
Thinking is to start impedance measurement module, confirmation electrode contact is good or meets electro-physiological signals acquisition after posting electrode
Impedance measurement is closed after resistance requirements and carries out signal acquisition, has detected whether electrode delamination simultaneously in signal acquisition.Impedance is surveyed
The processing circuit for measuring module is that constant pressure source exports stable voltage, after fixed resistance and electrode contact impedance are divided,
The voltage value at detecting electrode contact impedance both ends, by the corresponding relationship of the voltage value and impedance that detect, to obtain electrode
With the contact impedance value of skin.
It is big by monitoring mode application condition of the electric resistance partial pressure type to contact impedance, because electrode needs to connect human body, examine
Consider the safety of human body, constant voltage output cannot be too high, and when voltage value is not high enough, the changing value of contact impedance becomes in the voltage end of detection
Change is very little, so the contact impedance value error calculated can be very big.Existing equipment has electrode delamination monitoring, lacks in real time
Monitor contact impedance function.The reason is that the acquisition mode of existing equipment is electric resistance partial pressure mode, it is to access direct current on the electrode
Pressure, to real-time detection contact impedance, needs to continue to access DC voltage on the electrode, will affect adopting for Human Physiology electric signal
Collection, and there are security risks.
In addition, sleep analysis monitor is the acquisition equipment of data the whole night, so in monitoring system between electrode and skin
The acquisition of physiological electricity of human body EEG, ECG, EOG, EMG cannot be influenced when contact impedance, and can accurately test out impedance value to be
The important a part of entire acquisition system.A possibility that electrode loosens during sleeping at night is very big, and electrode loosens but without de-
The case where falling may cause contact impedance and become larger, and the signal quality of acquisition is deteriorated, to the last analysis of data the whole night and sleeping disorders
Judgement brings difficulty.And to equipment energy real-time monitoring contact impedance, then need the careful conscientiously observation of medical staff the whole night
Judge whether electrode contact is good, it is very high for the skill requirement of medical worker, experience the application of equipment bad.
Summary of the invention
In view of the above problems, it proposes on the present invention overcomes the above problem or at least be partially solved in order to provide one kind
State the signal deteching circuit of problem.
According to an aspect of the invention, there is provided a kind of signal deteching circuit, comprising: connect people by crosslinking electrode line
It the electro-physiological signals detection chip of body, contact impedance measuring circuit, buffer circuit, isolation circuit and is surveyed with the contact impedance
The signal processing circuit that amount circuit is connected with the electro-physiological signals detection chip;The contact impedance measuring circuit passes sequentially through
The buffer circuit and the isolation circuit are connect with the crosslinking electrode line;
The contact impedance measuring circuit is used to detect the contact impedance of the crosslinking electrode line and human skin;
The electro-physiological signals detection chip is given birth to for detecting body electrical signals, and carrying out differential amplification to be filtered
Manage electric signal;
The buffer circuit and the isolation circuit are used to be isolated the detection of the contact impedance to the electro-physiological signals
The influence of detection chip;
The signal processing circuit is used to assess the electro-physiological signals according to the contact impedance.
Signal deteching circuit according to the present invention, comprising: detected by the electro-physiological signals that crosslinking electrode line connects human body
Chip, contact impedance measuring circuit, buffer circuit, isolation circuit and with the contact impedance measuring circuit and the physiology electric
The signal processing circuit of signal detection chip connection;The contact impedance measuring circuit passes sequentially through the buffer circuit and described
Isolation circuit is connect with the crosslinking electrode line;The contact impedance measuring circuit is for detecting the crosslinking electrode line and human body
The contact impedance of skin;The electro-physiological signals detection chip carries out at differential amplification filtering for detecting body electrical signals
Reason obtains electro-physiological signals;The buffer circuit and the isolation circuit are used to be isolated the detection of the contact impedance to the life
Manage the influence of electrical signal detection chip;The signal processing circuit is used to assess the physiology telecommunications according to the contact impedance
Number.Contact using the scheme of the present embodiment, using contact impedance measuring circuit real-time detection crosslinking electrode line with human skin
Impedance, to guarantee the quality of electro-physiological signals under physiology pyroelectric monitor scene.
The above description is only an overview of the technical scheme of the present invention, in order to better understand the technical means of the present invention,
And it can be implemented in accordance with the contents of the specification, and in order to allow above and other objects of the present invention, feature and advantage can
It is clearer and more comprehensible, the followings are specific embodiments of the present invention.
Detailed description of the invention
By reading the following detailed description of the preferred embodiment, various other advantages and benefits are common for this field
Technical staff will become clear.The drawings are only for the purpose of illustrating a preferred embodiment, and is not considered as to the present invention
Limitation.And throughout the drawings, the same reference numbers will be used to refer to the same parts.In the accompanying drawings:
Fig. 1 shows the structure chart of signal deteching circuit according to an embodiment of the invention;
Fig. 2 shows the measurement model schematic diagrames of the contact impedance measuring circuit in Fig. 1;
Fig. 3 shows the constant-current source connection schematic diagram of a plurality of crosslinking electrode line;
Fig. 4 shows the structure chart of signal deteching circuit in accordance with another embodiment of the present invention;
Fig. 5 shows the structural schematic diagram of the multiway analog switch in Fig. 4;
Fig. 6 shows the structural schematic diagram of isolation circuit and buffer circuit.
Specific embodiment
Exemplary embodiments of the present disclosure are described in more detail below with reference to accompanying drawings.Although showing the disclosure in attached drawing
Exemplary embodiment, it being understood, however, that may be realized in various forms the disclosure without should be by embodiments set forth here
It is limited.On the contrary, these embodiments are provided to facilitate a more thoroughly understanding of the present invention, and can be by the scope of the present disclosure
It is fully disclosed to those skilled in the art.
Signal detecting mode in the prior art is to confirm that electrode contact is good or meets the resistance of electro-physiological signals acquisition
The case where i.e. closing impedance measurement carries out signal acquisition after anti-requirement, and electrode is loosened but do not fallen off in signal acquisition process may
Contact impedance is caused to become larger, the signal quality of acquisition is deteriorated.Based on this, in signal deteching circuit scheme of the invention, application
The contact impedance of contact impedance measuring circuit real-time detection crosslinking electrode line and human skin, to guarantee under physiology pyroelectric monitor scene
The quality of electro-physiological signals.
Fig. 1 shows the structure chart of signal deteching circuit according to an embodiment of the invention.As shown in Figure 1, the circuit
Include: contact impedance measuring circuit 10, by crosslinking electrode line connect human body electro-physiological signals detection chip 11 and with institute
State signal processing circuit 12, the isolation circuit of contact impedance measuring circuit 10 and the electro-physiological signals detection chip 11 connection
13, buffer circuit 14.The contact impedance measuring circuit 10 pass sequentially through the buffer circuit 14 and the isolation circuit 13 with
The crosslinking electrode line connection.
The contact impedance measuring circuit 10 is used to detect the contact impedance of the crosslinking electrode line and human skin;It is described
Electro-physiological signals detection chip 11 carries out differential amplification and is filtered to obtain electro-physiological signals for detecting body electrical signals.
The detection that the buffer circuit 14 and the isolation circuit 13 are used to be isolated the contact impedance detects the electro-physiological signals
The influence of chip 11;The signal processing circuit 12 is used to assess the electro-physiological signals according to the contact impedance.
In embodiments of the present invention, contact impedance measuring circuit 10 is to the contact impedance of crosslinking electrode line and human skin
Detection and electro-physiological signals detection chip 11 to the detection of body electrical signals be all in real time, it is and relatively independent, and signal
What processing circuit 12 then obtained electro-physiological signals detection chip 11 according to the contact impedance that contact impedance measuring circuit 10 detects
Electro-physiological signals are assessed.Specifically, signal processing circuit 12 determines whether contact impedance meets preset condition, if met
Preset condition illustrates that the contact of crosslinking electrode line is good, and the electro-physiological signals that electro-physiological signals detection chip 11 obtains are desirable, noise
It is relatively good.If being unsatisfactory for preset condition, illustrate electro-physiological signals detection chip 11 obtain electro-physiological signals signal quality compared with
Loosening occur in difference, crosslinking electrode line, and can issue alarm in time.Wherein, preset condition refer to the contact of crosslinking electrode line it is good or
Person meets the resistance requirements of electro-physiological signals acquisition, can be contact impedance in practical applications less than or equal to a preset resistance
Anti- value, specific value can according to need setting, and this is not restricted.After the contact impedance for realizing real-time detection electrode, only
There are electrode wires and loosen that alarm will be issued in time, sees the signal quality of equipment always there is no need to medical staff to judge electricity
Whether polar curve loosens, and is the easier intelligence of application of equipment.
Signal deteching circuit according to the present invention, the contact impedance measuring circuit 10 is for detecting the crosslinking electrode line
With the contact impedance of human skin;The electro-physiological signals detection chip 11 carries out difference and puts for detecting body electrical signals
Big filtering processing obtains electro-physiological signals;The buffer circuit 14 and the isolation circuit 13 are for being isolated the contact impedance
Detect the influence to the electro-physiological signals detection chip 11;The signal processing circuit 12 according to the contact impedance for commenting
Estimate the electro-physiological signals.Using the scheme of the present embodiment, using 10 real-time detection crosslinking electrode line of contact impedance measuring circuit
With the contact impedance of human skin, to guarantee the quality of electro-physiological signals under physiology pyroelectric monitor scene.
In embodiments of the present invention, contact impedance measuring circuit 10 includes voltage detection module 100 and the crosslinking electrode
The constant-current source 101 and the first analog-to-digital conversion output module 102 of line connection;The voltage detection module 100 is connected in parallel on described connect
The both ends of impedance are touched, the first analog-to-digital conversion output module 102 is connect with the signal processing circuit 12.The constant-current source
101 offer AC constant currents flow through the crosslinking electrode line and the contact impedance;The voltage detection module 100 detects institute
State the voltage at contact impedance both ends;The first analog-to-digital conversion output module 102 is according to the AC constant current and the electricity
Pressure obtains the impedance value of the contact impedance, and exports to the signal processing circuit 12.
Contact impedance test is in body electrical signals collection process while to carry out.The measurement mould of contact impedance measuring circuit
For type referring specifically to Fig. 2, crosslinking electrode line impedence is Re, and contact impedance measuring circuit 10 generates the AC constant current Is of very little,
It is connected on human body by crosslinking electrode line, flows through the equivalent contact impedance Rs between crosslinking electrode line and human skin, can produce
Pressure drop is given birth to, then detects the partial pressure Vs value at the both ends equivalent contact impedance Rs by contact impedance measuring circuit 10.According to Ohm's law, Is
In the case where constant, equivalent contact impedance Rs is bigger, and the partial pressure Vs at the both ends equivalent contact impedance Rs will be bigger, and there are direct proportions
Correlation.So the contact impedance calculated between crosslinking electrode line and human skin can be corresponded to according to partial pressure Vs value, connect
Touching impedance Rs meets following relationship: Rs=K*Vs/Is+M, wherein Vs is the described of contact impedance measuring circuit detection
The voltage at contact impedance both ends, Is are the AC constant current that the constant-current source provides, and K, M are relative coefficient.
In embodiments of the present invention, contact impedance measuring circuit 10 is based preferably on the realization of AFE4300 chip.It is based on
Contact impedance between the real-time accurate measurements crosslinking electrode line of AFE4300 chip platform and human skin can make the circuit of detection
It is simple easily to realize.
Electro-physiological signals detection chip 11 include the signal acquisition module 110 being connect with the crosslinking electrode line and with institute
State the second analog-to-digital conversion output module 111 of signal processing circuit connection.The signal acquisition module 110 detects the human body electricity
Signal;The second analog-to-digital conversion output module 111 body electrical signals are exported after differential amplification is filtered to
The signal processing circuit 12.
In an embodiment of the present invention, it is many to lead the crosslinking electrode number that sleeping device uses, electro-physiological signals detect core more
Piece 11 is connect by a plurality of crosslinking electrode line with human body, and the constant-current source flows through every lead using hub-and-spoke configuration
The AC constant current of the contact impedance in electrode wires is equal.As shown in figure 3, constant-current source 101 uses hub-and-spoke configuration,
The AC constant current of offer is flowed into from Iout1, is flowed out from Iout0.The end Iout1 of constant-current source 101 passes through capacitor C, resistance R1
Human body is connected with crosslinking electrode line, the end Iout0 of constant-current source 101 connects human body, crosslinking electrode line with public electrode by capacitor C
The one resistance R2 of parallel connection between public electrode wire.It is another that the end Iout1 of constant-current source 101 also passes through capacitor C, resistance R1, resistance R3
Capacitor C flows back to the end Iout0 of constant-current source 101, wherein there are also a resistance R2 is in parallel with resistance R3.In this way, the constant-current source 101
The AC constant current for flowing through the contact impedance on the every crosslinking electrode line using hub-and-spoke configuration is equal, i.e.,
The electric current for ensuring to flow through in each crosslinking electrode line is consistent.
When the acquisition of electro-physiological signals needs many crosslinking electrode lines to be used together, since the measurement of contact impedance is primary only
The contact impedance of a crosslinking electrode line can be detected, cannot a plurality of crosslinking electrode line detect simultaneously, so need increase control opens
It closes to switch over, contact impedance measuring circuit 10 is enabled successively to measure the contact impedance of each crosslinking electrode line.
Fig. 4 shows the structure chart of signal deteching circuit in accordance with another embodiment of the present invention.As shown in figure 4, signal
Detection circuit further includes a multiway analog switch 15, be connected to the contact impedance measuring circuit 10 and the buffer circuit 14 it
Between, for carrying out the switching between a plurality of crosslinking electrode line, it is ensured that successively measure a plurality of crosslinking electrode line and human body
The contact impedance.Due to contact impedance measurement cannot a plurality of crosslinking electrode line detect simultaneously, can only be one-time detection one
The contact impedance of crosslinking electrode line, so multiway analog switch 15 is needed to carry out the switching between crosslinking electrode line.
Multiway analog switch 15 include at least connect with the contact impedance measuring circuit 10 control terminal, output end, with
And multiple input terminals, each input terminal pass sequentially through the buffer circuit 14 and the isolation circuit 13 and lead electricity
Polar curve connection, the contact impedance measuring circuit 10 by the multiple input terminals of control terminal control successively with the output
End connection makes the contact impedance measuring circuit 10 successively measure the contact resistance of a plurality of crosslinking electrode line and human body
It is anti-.More specifically, the circuit block diagram of multiway analog switch 15 is as shown in Figure 5, it is preferable that use 4051 chips, including 16 are drawn
Foot, wherein the 1st, 2,4,5,12,13,14,15 pins be input terminal, the 3rd pin be output end, the 6th, 9,10,11 for control
End.3rd pin connects public electrode, and the 6th pin is to forbid holding, and when inputting as high level, which forbids, and disconnects, and inputs
When being zero, which is worked normally.6th pin connects supply voltage through resistance R11.7th, 8 pins are grounded, the 9th, 10,11 pins
It is connect with touching impedance measuring circuit 10.9th pin also connects supply voltage through resistance R12, and the 10th pin also connects power supply through resistance R13
Voltage, the 11st pin also connect supply voltage through resistance R14.16th pin connects supply voltage, also through first capacitor C1 in parallel and
Second capacitor C2 ground connection.1st, 2,4,5,12,13,14,15 pins isolation be followed by different crosslinking electrode lines.Touch impedance measurement electricity
Road 10 by the 6th, 9,10,11 pins control the 1st, 2,4,5,12,13,14,8 input terminals of 15 pins one of them with the
The conducting of 3 pins.
In the present embodiment, the input terminal of multiway analog switch 15 passes sequentially through the buffer circuit 14 and isolation electricity
Road 13 is connect with the crosslinking electrode line for being used as anode, and passes sequentially through the buffer circuit 14 and the isolation circuit 13
It is connect with the crosslinking electrode line for being used as cathode.With continued reference to Fig. 4, multiway analog switch 12 passes sequentially through 14 He of buffer circuit
Isolation circuit 13 is connect with positive crosslinking electrode line, is connected simultaneously also by buffer circuit 14 and isolation circuit 13 and negative crosslinking electrode line
It connects.
In embodiments of the present invention, isolation circuit 13 be connected to the multiway analog switch 15 and the crosslinking electrode line it
Between, the DC voltage for being isolated on the crosslinking electrode line can prevent DC voltage to be directly coupled to by crosslinking electrode line
Skin ambustion on human body plays the role of protecting personal safety.Buffer circuit 14 is connected to the multiway analog switch 15 and institute
It states between isolation circuit 13, for the physiology to be isolated when the multiway analog switch 15 switches or acquires the contact impedance
Acquisition of the electrical signal detection chip 11 to electro-physiological signals.Amplifier in buffer circuit 14 needs to select high input impedance, keeps away
Exempt to shunt by the Weak current on crosslinking electrode line.The setting of buffer circuit 14 can obstruct the switching of analog switch 15
Or to 11 normal acquisition physiology electric of electro-physiological signals detection chip when the acquisition contact impedance partial pressure value of contact impedance measuring circuit 10
The influence of signal is only accomplished not influencing normal acquisition electro-physiological signals, can just detect contact impedance in real time.
In the present embodiment, as shown in fig. 6, the isolation circuit 13 includes first capacitor C0, first resistor R0 and the
Two resistance R, the buffer circuit 14 include operational amplifier M;The output end m0 connection multichannel mould of the operational amplifier M
Quasi- switch 15, positive input terminal m1 connect with the first end of the first end of the first resistor R0 and the second resistance R, bear defeated
Enter to hold m2 to connect with the output end m0, the second termination power of the first resistor R0, the second termination of the second resistance R
Ground, the positive output end m1 of the operational amplifier M is also by the first capacitor C0 connection crosslinking electrode line, and passing through should
Crosslinking electrode line connects human body.
The contact impedance value accuracy of signal deteching circuit under this invention, the crosslinking electrode line and human body of test can be accomplished
5%, because the AC current values exported by AFE4300 are within 20uA, alternating current very it is faint be human body safe current value
Hereinafter, small electric current, after contact impedance, contact impedance variation is bigger, and the voltage value detected is more obvious.To collecting
Data carry out visual analyzing, it is found that there are very strong linear relationship between voltage value and impedance value, it is linear to calculate it
Correlation finds that its linear dependence numerical value is up to 0.9678.Least square method can be used and carry out multinomial linear fit, doing
Linear regression is carried out using 3 power multinomials when data algorithm processing.Most impedance measurements known to after verifying and true
Error between value is 5% hereinafter, improving the accuracy of contact impedance detected value.
Signal deteching circuit of the invention can more accurately measure the contact impedance of crosslinking electrode line and human body, for
Whether the differential amplification both ends input impedance of electro-physiological signals is matched with better judgement, to collect the better physiology of signal-to-noise ratio
Electric signal provides advantage.Moreover, it is achieved that after the contact impedance of real-time detection crosslinking electrode line, as long as there is crosslinking electrode
Line loosens will issue alarm in time, see the signal quality of equipment always there is no need to personnel to judge whether crosslinking electrode line is loose
It is de-, it is the easier intelligence of application of equipment.By the detection of real-time contact impedance to ensure that under physiology pyroelectric monitor scene
The quality of electro-physiological signals, electrode wires loosen auto-alarming, more embody the automatic intelligent feature of acquisition equipment.
Signal deteching circuit according to the present invention, comprising: detected by the electro-physiological signals that crosslinking electrode line connects human body
Chip, contact impedance measuring circuit, buffer circuit, isolation circuit and with the contact impedance measuring circuit and the physiology electric
The signal processing circuit of signal detection chip connection;The contact impedance measuring circuit passes sequentially through the buffer circuit and described
Isolation circuit is connect with the crosslinking electrode line;The contact impedance measuring circuit is for detecting the crosslinking electrode line and human body
The contact impedance of skin;The electro-physiological signals detection chip carries out at differential amplification filtering for detecting body electrical signals
Reason obtains electro-physiological signals;The buffer circuit and the isolation circuit are used to be isolated the detection of the contact impedance to the life
Manage the influence of electrical signal detection chip;The signal processing circuit is used to assess the physiology telecommunications according to the contact impedance
Number.Contact using the scheme of the present embodiment, using contact impedance measuring circuit real-time detection crosslinking electrode line with human skin
Impedance, to guarantee the quality of electro-physiological signals under physiology pyroelectric monitor scene.
In the instructions provided here, numerous specific details are set forth.It is to be appreciated, however, that implementation of the invention
Example can be practiced without these specific details.In some instances, well known method, structure is not been shown in detail
And technology, so as not to obscure the understanding of this specification.
Similarly, it should be understood that in order to simplify the disclosure and help to understand one or more of the various inventive aspects,
Above in the description of exemplary embodiment of the present invention, each feature of the invention is grouped together into single implementation sometimes
In example, figure or descriptions thereof.However, the disclosed method should not be interpreted as reflecting the following intention: i.e. required to protect
Shield the present invention claims features more more than feature expressly recited in each claim.More precisely, as following
Claims reflect as, inventive aspect is all features less than single embodiment disclosed above.Therefore,
Thus the claims for following specific embodiment are expressly incorporated in the specific embodiment, wherein each claim itself
All as a separate embodiment of the present invention.
Those skilled in the art will understand that can be carried out adaptively to the module in the equipment in embodiment
Change and they are arranged in one or more devices different from this embodiment.It can be the module or list in embodiment
Member or component are combined into a module or unit or component, and furthermore they can be divided into multiple submodule or subelement or
Sub-component.Other than such feature and/or at least some of process or unit exclude each other, it can use any
Combination is to all features disclosed in this specification (including adjoint claim, abstract and attached drawing) and so disclosed
All process or units of what method or apparatus are combined.Unless expressly stated otherwise, this specification is (including adjoint power
Benefit require, abstract and attached drawing) disclosed in each feature can carry out generation with an alternative feature that provides the same, equivalent, or similar purpose
It replaces.
In addition, it will be appreciated by those of skill in the art that although some embodiments described herein include other embodiments
In included certain features rather than other feature, but the combination of the feature of different embodiments mean it is of the invention
Within the scope of and form different embodiments.For example, in the following claims, embodiment claimed is appointed
Meaning one of can in any combination mode come using.
It should be noted that the above-mentioned embodiments illustrate rather than limit the invention, and ability
Field technique personnel can be designed alternative embodiment without departing from the scope of the appended claims.In the claims,
Any reference symbol between parentheses should not be configured to limitations on claims.Word "comprising" does not exclude the presence of not
Element or step listed in the claims.Word "a" or "an" located in front of the element does not exclude the presence of multiple such
Element.The present invention can be by means of including the hardware of several different elements and being come by means of properly programmed computer real
It is existing.If several in these circuits can be through the same hardware branch in the unit claim for listing dry circuit
To embody.The use of word first, second, and third does not indicate any sequence.These words can be explained and be run after fame
Claim.