CN114088950A - 基于c-c基序趋化因子配体14测量结果评价和治疗肾损伤和肾衰竭的方法和组合物 - Google Patents

基于c-c基序趋化因子配体14测量结果评价和治疗肾损伤和肾衰竭的方法和组合物 Download PDF

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Publication number
CN114088950A
CN114088950A CN202111365747.3A CN202111365747A CN114088950A CN 114088950 A CN114088950 A CN 114088950A CN 202111365747 A CN202111365747 A CN 202111365747A CN 114088950 A CN114088950 A CN 114088950A
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aki
subject
threshold
persistent
motif chemokine
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CN202111365747.3A
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Chinese (zh)
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J·P·肯普夫
P·麦克菲森
D·查尔芬
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Smart Medicine Co ltd
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Smart Medicine Co ltd
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    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/52Assays involving cytokines
    • G01N2333/521Chemokines
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/34Genitourinary disorders
    • G01N2800/347Renal failures; Glomerular diseases; Tubulointerstitial diseases, e.g. nephritic syndrome, glomerulonephritis; Renovascular diseases, e.g. renal artery occlusion, nephropathy
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/52Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00Detection or diagnosis of diseases
    • G01N2800/56Staging of a disease; Further complications associated with the disease

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
CN202111365747.3A 2017-01-12 2018-01-12 基于c-c基序趋化因子配体14测量结果评价和治疗肾损伤和肾衰竭的方法和组合物 Pending CN114088950A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201762445692P 2017-01-12 2017-01-12
US62/445,692 2017-01-12
CN201880012782.7A CN110651187A (zh) 2017-01-12 2018-01-12 基于c-c基序趋化因子配体14测量结果评价和治疗肾损伤和肾衰竭的方法和组合物

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CN114088950A true CN114088950A (zh) 2022-02-25

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CN202111365747.3A Pending CN114088950A (zh) 2017-01-12 2018-01-12 基于c-c基序趋化因子配体14测量结果评价和治疗肾损伤和肾衰竭的方法和组合物
CN201880012782.7A Pending CN110651187A (zh) 2017-01-12 2018-01-12 基于c-c基序趋化因子配体14测量结果评价和治疗肾损伤和肾衰竭的方法和组合物

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Country Status (8)

Country Link
US (2) US11353465B2 (https=)
EP (2) EP3568695A4 (https=)
JP (2) JP2020504157A (https=)
CN (2) CN114088950A (https=)
AU (1) AU2018207151B2 (https=)
CA (1) CA3049444A1 (https=)
MX (1) MX2019008260A (https=)
WO (1) WO2018132702A1 (https=)

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JP2020504157A (ja) * 2017-01-12 2020-02-06 アスチュート メディカル,インコーポレイテッド C−cモチーフケモカインリガンド14の測定に基づく腎損傷および腎不全の評価および処置のための方法および組成物
US11891439B2 (en) 2017-12-28 2024-02-06 Astute Medical, Inc. Antibodies and assays for CCL14
CN114207436A (zh) * 2019-05-24 2022-03-18 机敏医药股份有限公司 基于c-c基序趋化因子配体14测量而评估和治疗肾损伤的方法
CN114341178B (zh) * 2019-07-02 2024-05-07 机敏医药股份有限公司 Ccl14的抗体和检测
AU2021381364A1 (en) * 2020-11-18 2023-06-22 Astute Medical, Inc. Methods and compositions for treatment of renal injury and renal failure
CN113555122B (zh) * 2021-07-21 2024-04-26 中南大学湘雅二医院 一种重症脓毒症患者一过性和持续性aki的预测模型及其构建方法
WO2023168299A1 (en) * 2022-03-03 2023-09-07 Astute Medical, Inc. Methods and compositions for assessing and treating persistent acute kidney injury based on c-c motif chemokine ligand 14 measurement

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Also Published As

Publication number Publication date
EP4063853A1 (en) 2022-09-28
AU2018207151A1 (en) 2019-07-18
US20230025225A1 (en) 2023-01-26
CA3049444A1 (en) 2018-07-19
EP3568695A4 (en) 2020-12-16
MX2019008260A (es) 2020-01-27
AU2018207151B2 (en) 2024-02-29
US11353465B2 (en) 2022-06-07
JP2020504157A (ja) 2020-02-06
JP2022091846A (ja) 2022-06-21
EP3568695A1 (en) 2019-11-20
US12203944B2 (en) 2025-01-21
US20190339289A1 (en) 2019-11-07
WO2018132702A1 (en) 2018-07-19
CN110651187A (zh) 2020-01-03

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