CN114088950A - 基于c-c基序趋化因子配体14测量结果评价和治疗肾损伤和肾衰竭的方法和组合物 - Google Patents
基于c-c基序趋化因子配体14测量结果评价和治疗肾损伤和肾衰竭的方法和组合物 Download PDFInfo
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G—PHYSICS
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- G01N2333/435—Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
- G01N2333/52—Assays involving cytokines
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- G01N2800/34—Genitourinary disorders
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| US11891439B2 (en) | 2017-12-28 | 2024-02-06 | Astute Medical, Inc. | Antibodies and assays for CCL14 |
| CN114207436A (zh) * | 2019-05-24 | 2022-03-18 | 机敏医药股份有限公司 | 基于c-c基序趋化因子配体14测量而评估和治疗肾损伤的方法 |
| CN114341178B (zh) * | 2019-07-02 | 2024-05-07 | 机敏医药股份有限公司 | Ccl14的抗体和检测 |
| AU2021381364A1 (en) * | 2020-11-18 | 2023-06-22 | Astute Medical, Inc. | Methods and compositions for treatment of renal injury and renal failure |
| CN113555122B (zh) * | 2021-07-21 | 2024-04-26 | 中南大学湘雅二医院 | 一种重症脓毒症患者一过性和持续性aki的预测模型及其构建方法 |
| WO2023168299A1 (en) * | 2022-03-03 | 2023-09-07 | Astute Medical, Inc. | Methods and compositions for assessing and treating persistent acute kidney injury based on c-c motif chemokine ligand 14 measurement |
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| CN103080743A (zh) * | 2010-06-23 | 2013-05-01 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后的方法和组合物 |
| WO2016064877A2 (en) * | 2014-10-20 | 2016-04-28 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
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| US5223409A (en) | 1988-09-02 | 1993-06-29 | Protein Engineering Corp. | Directed evolution of novel binding proteins |
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| CA2072758A1 (en) | 1990-09-14 | 1992-03-15 | Kenneth Francis Buechler | Antibodies to complexes of ligand receptors and ligands and their utility in ligand-receptor assays |
| US5955377A (en) | 1991-02-11 | 1999-09-21 | Biostar, Inc. | Methods and kits for the amplification of thin film based assays |
| CA2107894C (en) | 1991-04-10 | 2003-10-14 | Kenneth F. Buechler | Crosstalk inhibitors and their uses |
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| US20120156701A1 (en) | 2009-12-20 | 2012-06-21 | Joseph Anderberg | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| PT2666872T (pt) | 2010-02-05 | 2016-07-08 | Astute Medical Inc | Processos e composições para o diagnóstico e o prognóstico de lesões renais e de insuficiência renal |
| IN2012MN02812A (https=) | 2010-06-23 | 2015-05-22 | Astute Medical Inc | |
| NZ605698A (en) | 2010-06-23 | 2015-03-27 | Astute Medical Inc | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
| EP2694974B1 (en) * | 2011-04-04 | 2015-10-21 | Universiteit Gent | Biomarkers for acute kidney injury |
| CN103874923B (zh) | 2011-08-26 | 2016-09-14 | 阿斯图特医药公司 | 用于肾损伤和肾衰竭的诊断及预后的方法和组合物 |
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| WO2013096740A1 (en) | 2011-12-21 | 2013-06-27 | Alere San Diego Inc. | Methods and compositions for assigning likelihood of chronic kidney disease progression |
| JP2020504157A (ja) * | 2017-01-12 | 2020-02-06 | アスチュート メディカル,インコーポレイテッド | C−cモチーフケモカインリガンド14の測定に基づく腎損傷および腎不全の評価および処置のための方法および組成物 |
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| WO2016064877A2 (en) * | 2014-10-20 | 2016-04-28 | Astute Medical, Inc. | Methods and compositions for diagnosis and prognosis of renal injury and renal failure |
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| EP3568695A1 (en) | 2019-11-20 |
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| US20190339289A1 (en) | 2019-11-07 |
| WO2018132702A1 (en) | 2018-07-19 |
| CN110651187A (zh) | 2020-01-03 |
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