CN114082020A - Automatic citric acid anticoagulation equipment for hemodialysis and control system thereof - Google Patents
Automatic citric acid anticoagulation equipment for hemodialysis and control system thereof Download PDFInfo
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- CN114082020A CN114082020A CN202111618969.1A CN202111618969A CN114082020A CN 114082020 A CN114082020 A CN 114082020A CN 202111618969 A CN202111618969 A CN 202111618969A CN 114082020 A CN114082020 A CN 114082020A
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- citric acid
- hemodialysis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
- A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
- A61M1/1621—Constructional aspects thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3621—Extra-corporeal blood circuits
- A61M1/367—Circuit parts not covered by the preceding subgroups of group A61M1/3621
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
- A61M1/36—Other treatment of blood in a by-pass of the natural circulatory system, e.g. temperature adaptation, irradiation ; Extra-corporeal blood circuits
- A61M1/3687—Chemical treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
- A61M2205/3334—Measuring or controlling the flow rate
Abstract
The invention relates to automatic citric acid anticoagulation equipment for hemodialysis, which comprises a first citric acid pump and a second citric acid pump, wherein the first citric acid pump is connected to an arterial segment of a hemodialysis pipeline through a pipeline, and the second citric acid pump is connected to a venous kettle of the hemodialysis pipeline through a pipeline. According to the automatic citric acid anticoagulation equipment and the control system thereof, the infusion amounts of two citric acid pumps under different blood flow speeds and in vivo ionized calcium levels are automatically calculated according to a binary primary equation obtained by research of an inventor in clinical work, automatic calculation and automatic infusion are realized, verification research under the conditions of different types of citric acid anticoagulants, more types of dialyzers, wider blood flow speeds and larger ionized calcium ranges is carried out, and a very good effect is obtained.
Description
Technical Field
The invention relates to the technical field of anticoagulation of citric acid in hemodialysis, in particular to automatic citric acid anticoagulation equipment for hemodialysis and a control system thereof.
Background
Anticoagulation is a necessary condition for ensuring smooth hemodialysis, heparin and low-molecular heparin are the first choice for anticoagulation at present, but the anticoagulation method affects the whole-body blood coagulation function, has bleeding risks, is combined with bleeding tendency or can not be used by patients with active bleeding, and the patients usually adopt heparin-free dialysis, and clinical researches find that the prognosis can not be improved by the heparin-free dialysis, and also have the defects of insufficient dialysis, uncertain ultrafiltration volume, blood loss, thromboembolic diseases and the like.
Morita reports for the first time in 1961 that citric acid anticoagulation technology is used in hemodialysis, and the method comprises the steps of infusing a proper amount of citric acid preparation into the arterial end of an extracorporeal circulation pipeline of hemodialysis, reducing the level of ionized calcium in the extracorporeal circulation, interrupting the coagulation reaction process, then infusing the calcium preparation into the venous end to restore the level of the ionized calcium in the extracorporeal circulation, so that the extracorporeal circulation pipeline is ensured not to generate coagulation under the condition of a precursor which does not influence the activity of systemic coagulation, the method has good anticoagulation effect, but has complex operation, can generate serious hypocalcemia, electrolyte and acid-base balance disorder and other adverse reactions, and the used calcium-free dialysate does not have commercial finished products at home, at present, the citric acid anticoagulation is increasingly applied to the hemodialysis, various improved schemes are developed for reducing the operation complexity and the risk of the adverse reactions as much as possible, and the schemes all adopt fixed blood flow rate, the method comprises the steps of giving a fixed initial citric acid preparation infusion speed according to the blood flow speed, adjusting the subsequent citric acid preparation speed and the calcium supplementing speed by frequently detecting the concentration of ionized calcium in a patient body and after a filter to ensure safety and effectiveness, wherein the method cannot realize individualized treatment, the ionized calcium monitoring frequency is frequent, the cost is high, the conventional development is difficult, and a dose comparison table for infusing the citric acid preparation at different blood flow speeds is found out through clinical experience by people.
Disclosure of Invention
Aiming at the defects of the prior art, the invention provides automatic citric acid anticoagulation equipment for hemodialysis and a control system thereof, which have the advantages of simple use, low cost, guaranteed anticoagulation effect and the like, and solve the problems that the blood flow speed of the method can not be freely switched and the influence of the ionized calcium level in a patient on the anticoagulation effect and the safety is neglected when a dosage comparison table for infusing the citric acid preparation at different blood flow speeds is found out through clinical experience.
In order to achieve the purpose, the invention provides the following technical scheme: the utility model provides an automatic citric acid anticoagulation equipment for hemodialysis, includes No. one citric acid pump and No. two citric acid pumps, No. one citric acid pump passes through the pipe connection at the arterial segment of hemodialysis pipeline, No. two citric acid pumps pass through the pipe connection on the venous kettle of hemodialysis pipeline.
The operation scheme is as follows:
1) measuring the concentration of ionized calcium in the treatment precursor of the patient by using a blood gas analyzer, and inputting the measured concentration into an automatic citric acid anticoagulation device;
2) installing an extracorporeal circulation pipeline, a dialyzer and dialysate on the hemodialysis machine according to the conventional method, and completing preparation before treatment;
3) connecting an automatic citric acid anticoagulation equipment pipeline, and connecting the automatic citric acid anticoagulation equipment pipeline with an arterial segment and a venous pot of an extracorporeal circulation pipeline;
4) setting the blood flow velocity of a hemodialysis machine, and automatically reading the set blood flow velocity by an automatic citric acid anticoagulation device;
5) connecting a citric acid anticoagulant in automatic citric acid anticoagulant equipment;
6) starting a hemodialysis machine to drain blood from the body of a patient, automatically calculating the citric acid infusion speed by an automatic citric acid anticoagulation device according to set parameters, and respectively inputting the citric acid infusion speed into an arterial end and a venous pot of an extracorporeal circulation pipeline through infusion pumps;
7) measuring the ionized calcium concentration in the treatment precursor of the patient by using a blood gas analyzer after 1 hour of treatment, and automatically correcting the citric acid infusion pump by the automatic citric acid anticoagulation equipment according to the ionized calcium concentration and the blood flow speed;
8) if the blood flow speed is adjusted in the treatment process, the automatic citric acid anticoagulation equipment can automatically read the parameters of the hemodialysis machine and automatically adjust the citric acid infusion speed;
9) after the treatment is finished, the blood is discharged according to the conventional hemodialysis flow, and the automatic citric acid anticoagulation equipment automatically stops infusing the citric acid anticoagulation agent, so that the treatment is finished.
Furthermore, the citric acid pump I flows to the arterial segment of the hemodialysis extracorporeal circulation pipeline in a one-way mode through a guide pipe, the citric acid pump II flows to the venous pot in a one-way mode through the guide pipe, and the blood of a human body is connected with the dialyzer in a one-way mode through the extracorporeal circulation pipeline.
Further, the treatment module consists of a blood ionized calcium concentration regulating module, a blood flow speed regulating module, a citric acid preparation type selecting module, a citric acid trisodium concentration regulating module and a citric acid preparation selecting module.
Furthermore, the treatment module consists of two infusion pumps, the infusion speed of each infusion pump is 0-1000ml/h, the blood ionized calcium concentration adjusting module controls the blood ionized calcium concentration through keys, the adjusting range is 0-5, and the minimum scale is 0.1.
Further, the blood flow speed adjusting module adjusts the blood flow speed through a key, the adjusting value is 0-1000, the minimum scale is 1, and the citric acid preparation type selecting module selects the blood preservation solution and the 4% sodium citrate injection through the key.
Further, the trisodium citrate concentration adjusting module is used for adjusting the concentration of trisodium citrate through key data, wherein the numerical value is 0-100, and the minimum scale is 0.1.
Compared with the prior art, the technical scheme of the application has the following beneficial effects:
1. the automatic citric acid anticoagulation equipment for hemodialysis and the control system thereof have the advantages that under the condition of using a dialysate with the calcium content of 1.5mmol/L, the citric acid concentration in external circulation under the premise of obtaining satisfactory citric acid anticoagulation in vitro and the ionized calcium concentration before treatment of a patient show obvious linear correlation, the effectiveness and the safety under the conditions of dialyzers with different models, dialyzers with different blood flow speeds, different vascular passages, arterial blood or venous blood measurement ionized calcium concentration and the like are all obtained with satisfactory effects, a calculator for automatically calculating the citric acid infusion amount under different blood flow speeds and internal ionized calcium levels is calculated, the material object manufacturing is completed, and the verification research under the conditions of different types of citric acid anticoagulation agents, more types of dialyzers, wider blood flow speeds and larger ionized calcium ranges is carried out in single-center clinical research, and the same excellent effect is obtained, the scheme is simple to use, low in cost, and capable of ensuring the anticoagulation effect, simultaneously, the safety is not input into the conventional method, the corresponding citric acid dosage can be automatically calculated and infused only by inputting corresponding parameters, and the smooth proceeding of treatment is ensured.
2. The automatic citric acid anticoagulation equipment for hemodialysis and the control system thereof adjust and select the blood ionized calcium concentration, the blood flow speed, the citric acid preparation type and the citric acid trisodium concentration by adopting a switching treatment mode, set data by dynamic adjustment, observe the data in a visual screen, thereby carrying out real-time control, detect the flow of blood by adopting flow detection and calculation, calculate through the blood flow speed and the flow speed of the citric acid anticoagulant, carry out real-time adjustment and control according to the data obtained by calculation, ensure the citric acid anticoagulant and the blood to be fully mixed, improve the dosage and the flow speed of the citric acid anticoagulant by scientific calculation, ensure the safety and the specialty in the dialysis process, realize full-automatic flow by intelligent control, save labor force, avoid errors in manual operation, and the automatic citric acid anticoagulation equipment and the control system thereof, according to a binary first-order equation obtained by research of the inventor in clinical work, the infusion amount of the two citric acid pumps under different blood flow speeds and in vivo ionized calcium levels is automatically calculated, and automatic calculation and automatic infusion are realized.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic view of the working process of the present invention;
FIG. 3 is a functional block diagram of the present invention.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Referring to fig. 1-3, the automated citric acid anticoagulation device for hemodialysis in the present embodiment includes a first citric acid pump and a second citric acid pump, wherein the first citric acid pump is connected to an arterial segment of a hemodialysis pipeline through a pipeline, and the second citric acid pump is connected to a venous kettle of the hemodialysis pipeline through a pipeline. According to the automatic citric acid anticoagulation equipment and the control system thereof, the infusion amounts of two citric acid pumps under different blood flow speeds and in vivo ionized calcium levels are automatically calculated according to a binary primary equation obtained by research of an inventor in clinical work, so that automatic calculation and automatic infusion are realized. By using the dialysate with the calcium content of 1.5mmol/L, the citric acid concentration in the extracorporeal circulation under the premise of obtaining satisfactory citric acid anticoagulation in vitro and the ionized calcium concentration of a patient before treatment are obviously linearly related, the effectiveness and the safety under the conditions of measuring the ionized calcium concentration by different models of dialyzers, different blood flow speeds, different blood vessel passages, taking arterial blood or venous blood and the like are all obtained with satisfactory effects, a calculator for automatically calculating the citric acid infusion amount under different blood flow speeds and the ionized calcium level in vivo is calculated, the material object manufacturing is completed, and the verification and research under the conditions of different types of citric acid anticoagulation agents, more dialyzers, wider blood flow speeds and wider ionized calcium range are carried out in the single-center clinical research, so that the very good effect is also obtained, the scheme has the advantages of simple use, low cost, ensured anticoagulation effect and no input of the safety into the conventional method, corresponding citric acid dosage can be automatically calculated and infused only by inputting corresponding parameters, so that smooth treatment is ensured;
the operation scheme is as follows:
1) measuring the concentration of ionized calcium in the treatment precursor of the patient by using a blood gas analyzer, and inputting the measured concentration into an automatic citric acid anticoagulation device;
2) installing an extracorporeal circulation pipeline, a dialyzer and dialysate on the hemodialysis machine according to the conventional method, and completing preparation before treatment;
3) connecting an automatic citric acid anticoagulation equipment pipeline, and connecting the automatic citric acid anticoagulation equipment pipeline with an arterial segment and a venous pot of an extracorporeal circulation pipeline;
4) setting the blood flow velocity of a hemodialysis machine, and automatically reading the set blood flow velocity by an automatic citric acid anticoagulation device;
5) connecting a citric acid anticoagulant in automatic citric acid anticoagulant equipment;
6) starting a hemodialysis machine to drain blood from the body of a patient, automatically calculating the citric acid infusion speed by an automatic citric acid anticoagulation device according to set parameters, and respectively inputting the citric acid infusion speed into an arterial end and a venous pot of an extracorporeal circulation pipeline through infusion pumps;
7) measuring the ionized calcium concentration in the treatment precursor of the patient by using a blood gas analyzer after 1 hour of treatment, and automatically correcting the citric acid infusion pump by the automatic citric acid anticoagulation equipment according to the ionized calcium concentration and the blood flow speed;
8) if the blood flow speed is adjusted in the treatment process, the automatic citric acid anticoagulation equipment can automatically read the parameters of the hemodialysis machine and automatically adjust the citric acid infusion speed;
9) after the treatment is finished, the blood is discharged according to the conventional hemodialysis flow, and the automatic citric acid anticoagulation equipment automatically stops infusing the citric acid anticoagulation agent, so that the treatment is finished.
An automatic citric acid anticoagulation control system comprises a treatment module, wherein the treatment module is composed of a blood ionized calcium concentration adjusting module and two infusion pumps, the infusion speed of each infusion pump is 0-1000ml/h, the blood ionized calcium concentration adjusting module controls the blood ionized calcium concentration through keys, the adjusting range is 0-5, the minimum scale is 0.1, a blood flow speed adjusting module and a citric acid preparation type selecting module, the blood flow speed adjusting module adjusts the blood flow speed through keys, the adjusting value is 0-1000, the minimum scale is 1, the citric acid preparation type selecting module selects blood preservation solution (ACD-A) and 4% citric acid sodium injection through keys, the citric acid trisodium concentration adjusting module adjusts the trisodium concentration through key data, the value is 0-100, the minimum scale is 0.1, the citric acid preparation selection module is composed of a treatment switching mode, blood ionic calcium concentration, blood flow speed, citric acid preparation type and citric acid trisodium concentration are adjusted and selected, data setting is carried out through dynamic adjustment, data are observed in a visual screen, real-time control is carried out, flow detection and calculation are adopted to detect the flow of blood, calculation is carried out through the blood flow speed and the flow speed of citric acid anticoagulant, real-time adjustment and control are carried out according to the calculated data, the citric acid anticoagulant and the blood are fully mixed, the dosage and the flow speed of the citric acid anticoagulant are improved through scientific calculation, safety and specialty in the dialysis process are guaranteed, intelligent control can realize full-automatic flow, labor force is saved, errors in manual operation are avoided, and the automatic citric acid anticoagulant equipment and the control system thereof, according to a binary first-order equation obtained by research of the inventor in clinical work, the infusion amount of the two citric acid pumps under different blood flow speeds and in vivo ionized calcium levels is automatically calculated, and automatic calculation and automatic infusion are realized.
When the citric acid preparation is selected as blood preservation solution (ACD-a), the blood flow rate is (i + o) (iCa 0.405+2.306) × 60/113;
when the citric acid preparation is selected to be 4% citric acid sodium disodium injection, the blood flow rate is multiplied by 60/136 (0.405 and 2.306 of iCa);
when the concentration of the trisodium citrate is selected to be Y percent, the concentration is (i) and (i) 0.405 and 2.306) multiplied by the blood flow velocity multiplied by 60 multiplied by 294.1/10000Y;
first, second, default speed of pump: (r + ②) × 4/5; (ii) × 1/5, which can also be manually adjusted at this default speed;
the first row and the second row display the ratio: x is 1;
wherein, the first and the second represent a first citric acid pump and a second citric acid pump respectively.
In conclusion, the automatic citric acid anticoagulation equipment for hemodialysis and the control system thereof have the advantages that under the condition of using the dialysate with the calcium content of 1.5mmol/L, the citric acid concentration in the external circulation under the premise of obtaining satisfactory citric acid in-vitro anticoagulation and the ionized calcium concentration of a patient before treatment are obviously linearly related, the effectiveness and the safety under the conditions of measuring the ionized calcium concentration by dialyzers with different models, dialyzers with different blood flow speeds, different blood vessel passages, arterial blood or venous blood and the like are all obtained with satisfactory effects, a calculator for automatically calculating the citric acid infusion amount under the conditions of different blood flow speeds and internal ionized calcium levels is calculated, the material object manufacturing is completed, the verification research under the conditions of different types of citric acid anticoagulants, more types of dialyzers, wider blood flow speeds and larger ionized calcium ranges is carried out in the single-center clinical research, and the excellent effects are also obtained, the scheme is simple to use, low in cost, and capable of ensuring the anticoagulation effect, simultaneously, the safety is not input into the conventional method, the corresponding citric acid dosage can be automatically calculated and infused only by inputting corresponding parameters, and the smooth proceeding of treatment is ensured.
Further, by adopting a switching treatment mode, the blood ionic calcium concentration, the blood flow speed, the citric acid preparation type and the citric acid trisodium concentration are adjusted and selected, data are set through dynamic adjustment, data are observed in a visual screen, real-time control is carried out, the flow of blood is detected through flow detection and calculation, the blood flow speed and the flow speed of the citric acid anticoagulant are calculated, real-time adjustment and control are carried out according to the calculated data, the citric acid anticoagulant and the blood are fully mixed, the dosage and the flow speed of the citric acid anticoagulant are improved through scientific calculation, the safety and the specialty in the dialysis process are ensured, full-automatic flow can be realized through intelligent control, labor force is saved, and errors in manual operation are avoided The infusion amount of the two citric acid pumps under the level of the internal ionized calcium realizes automatic calculation and automatic infusion.
It is noted that, herein, relational terms such as first and second, and the like may be used solely to distinguish one entity or action from another entity or action without necessarily requiring or implying any actual such relationship or order between such entities or actions. Also, the terms "comprises," "comprising," or any other variation thereof, are intended to cover a non-exclusive inclusion, such that a process, method, article, or apparatus that comprises a list of elements does not include only those elements but may include other elements not expressly listed or inherent to such process, method, article, or apparatus. Without further limitation, an element defined by the phrase "comprising an … …" does not exclude the presence of other identical elements in a process, method, article, or apparatus that comprises the element.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (6)
1. The utility model provides an automatic citric acid anticoagulation equipment for hemodialysis, includes No. one citric acid pump and No. two citric acid pumps, No. one citric acid pump passes through the pipe connection at the arterial segment of hemodialysis pipeline, No. two citric acid pumps pass through the pipe connection on the venous kettle of hemodialysis pipeline.
The operation scheme is as follows:
1) measuring the concentration of ionized calcium in the treatment precursor of the patient by using a blood gas analyzer, and inputting the measured concentration into an automatic citric acid anticoagulation device;
2) installing an extracorporeal circulation pipeline, a dialyzer and dialysate on the hemodialysis machine according to the conventional method, and completing preparation before treatment;
3) connecting an automatic citric acid anticoagulation equipment pipeline, and connecting the automatic citric acid anticoagulation equipment pipeline with an arterial segment and a venous pot of an extracorporeal circulation pipeline;
4) setting the blood flow velocity of a hemodialysis machine, and automatically reading the set blood flow velocity by an automatic citric acid anticoagulation device;
5) connecting a citric acid anticoagulant in automatic citric acid anticoagulant equipment;
6) starting a hemodialysis machine to drain blood from the body of a patient, automatically calculating the citric acid infusion speed by an automatic citric acid anticoagulation device according to set parameters, and respectively inputting the citric acid infusion speed into an arterial end and a venous pot of an extracorporeal circulation pipeline through infusion pumps;
7) measuring the ionized calcium concentration in the treatment precursor of the patient by using a blood gas analyzer after 1 hour of treatment, and automatically correcting the citric acid infusion pump by the automatic citric acid anticoagulation equipment according to the ionized calcium concentration and the blood flow speed;
8) if the blood flow speed is adjusted in the treatment process, the automatic citric acid anticoagulation equipment can automatically read the parameters of the hemodialysis machine and automatically adjust the citric acid infusion speed;
9) after the treatment is finished, the blood is discharged according to the conventional hemodialysis flow, and the automatic citric acid anticoagulation equipment automatically stops infusing the citric acid anticoagulation agent, so that the treatment is finished.
2. The automated citric acid anticoagulation device for hemodialysis and the control system thereof according to claim 1, characterized in that: the first citric acid pump flows to the arterial segment of the hemodialysis extracorporeal circulation pipeline in a one-way mode through a guide pipe, the second citric acid pump flows to the venous pot in a one-way mode through the guide pipe, and the blood of a human body is connected with the dialyzer in a one-way mode through the extracorporeal circulation pipeline.
3. The automated citric acid anticoagulation device for hemodialysis and the control system thereof according to claim 1, characterized in that: the treatment module consists of a blood ionic calcium concentration regulating module, a blood flow speed regulating module, a citric acid preparation type selecting module, a citric acid trisodium concentration regulating module and a citric acid preparation selecting module.
4. The automated citric acid anticoagulation device for hemodialysis and the control system thereof according to claim 3, wherein: the treatment module consists of two infusion pumps, the infusion speed of each infusion pump is 0-1000ml/h, the blood ionized calcium concentration adjusting module controls the blood ionized calcium concentration through keys, the adjusting range is 0-5, and the minimum scale is 0.1.
5. The automated citric acid anticoagulation device for hemodialysis and the control system thereof according to claim 3, wherein: the blood flow speed adjusting module adjusts the blood flow speed through a key, the adjusting value is 0-1000, the minimum scale is 1, and the citric acid preparation type selecting module selects the blood preservation solution and the 4% sodium citrate injection through the key.
6. The automated citric acid anticoagulation device for hemodialysis and the control system thereof according to claim 3, wherein: the trisodium citrate concentration adjusting module is used for adjusting the trisodium citrate concentration according to the specific concentration data of the key data, wherein the numerical value is 0-100, and the minimum scale is 0.1.
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| Application Number | Priority Date | Filing Date | Title |
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| CN202111618969.1A CN114082020A (en) | 2021-12-27 | 2021-12-27 | Automatic citric acid anticoagulation equipment for hemodialysis and control system thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN202111618969.1A CN114082020A (en) | 2021-12-27 | 2021-12-27 | Automatic citric acid anticoagulation equipment for hemodialysis and control system thereof |
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| CN114082020A true CN114082020A (en) | 2022-02-25 |
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Application publication date: 20220225 |