CN114076708B - Automatic mixing device and sample analyzer - Google Patents
Automatic mixing device and sample analyzer Download PDFInfo
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- CN114076708B CN114076708B CN202010761305.XA CN202010761305A CN114076708B CN 114076708 B CN114076708 B CN 114076708B CN 202010761305 A CN202010761305 A CN 202010761305A CN 114076708 B CN114076708 B CN 114076708B
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- 238000002156 mixing Methods 0.000 title claims abstract description 111
- 230000001360 synchronised effect Effects 0.000 claims abstract description 68
- 230000007246 mechanism Effects 0.000 claims description 55
- 238000005452 bending Methods 0.000 claims description 30
- 230000033001 locomotion Effects 0.000 claims description 18
- 238000005070 sampling Methods 0.000 claims description 9
- 239000002184 metal Substances 0.000 claims description 2
- 240000009087 Crescentia cujete Species 0.000 claims 4
- 235000005983 Crescentia cujete Nutrition 0.000 claims 4
- 235000009797 Lagenaria vulgaris Nutrition 0.000 claims 4
- 238000012360 testing method Methods 0.000 description 37
- 241000219122 Cucurbita Species 0.000 description 10
- 235000009852 Cucurbita pepo Nutrition 0.000 description 10
- 238000001514 detection method Methods 0.000 description 10
- 230000009471 action Effects 0.000 description 8
- 230000005540 biological transmission Effects 0.000 description 8
- 239000008280 blood Substances 0.000 description 5
- 210000004369 blood Anatomy 0.000 description 5
- 230000000670 limiting effect Effects 0.000 description 4
- 238000012423 maintenance Methods 0.000 description 4
- 238000000034 method Methods 0.000 description 4
- 230000008569 process Effects 0.000 description 4
- 230000003014 reinforcing effect Effects 0.000 description 4
- 239000000758 substrate Substances 0.000 description 4
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000004891 communication Methods 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 230000002349 favourable effect Effects 0.000 description 2
- 238000009434 installation Methods 0.000 description 2
- 230000010355 oscillation Effects 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000005484 gravity Effects 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
Classifications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/38—Diluting, dispersing or mixing samples
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Pathology (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Abstract
The application relates to the field of medical equipment and instruments, and particularly discloses an automatic mixing device and a sample analyzer, wherein the automatic mixing device comprises: a bracket and a synchronous pulley shaft; the bracket at least comprises: the device comprises a first vertical plate and a synchronous pulley mounting frame arranged on the first vertical plate, wherein the synchronous pulley mounting frame comprises a first side wall, a second side wall and a bottom wall, the first side wall and the second side wall are oppositely arranged, the bottom wall is connected with the first side wall and the second side wall, and the first side wall, the bottom wall and the second side wall form a U-shaped structure; opposite ends of the synchronous pulley shaft are respectively arranged on the first side wall and the second side wall, and the first side wall is fixedly arranged on the first vertical plate. Through the mode, when the automatic mixing device works, the synchronous belt is not easy to fall off from the synchronous belt wheel, the synchronous belt wheel is not easy to loose or fall off, meanwhile, the stability and the reliability of the device are effectively improved, and meanwhile, the automatic mixing device is simple in structure and convenient to maintain.
Description
Technical Field
The application relates to the field of medical equipment and instruments, in particular to an automatic mixing device and a sample analyzer.
Background
In clinical test instruments, such as blood analyzers, it is necessary to thoroughly and reasonably mix the sample contained in the test tube sample holder prior to sampling. The synchronous belt is an important component in the blood analyzer, and a plurality of moving mechanisms are arranged in the blood analyzer, so that the synchronous belt is required to drive the moving mechanisms to move back and forth.
In the long-term research and development process, the inventor of the application finds that the synchronous pulley of the existing blood analyzer is fixed by a single side, and the synchronous pulley is easy to loosen and fall off, so that the blood analyzer is seriously failed.
Disclosure of Invention
The application aims to solve the problems in the prior art to a certain extent, and provides an automatic mixing device and a sample analyzer, wherein a synchronous belt is not easy to fall off from a synchronous belt wheel when the automatic mixing device works, the synchronous belt wheel is not easy to loosen or fall off, meanwhile, the stability and the reliability of the device are effectively improved, and meanwhile, the automatic mixing device is simple in structure and convenient to maintain.
In order to solve the technical problems, the application adopts a technical scheme that: an automatic mixing device is provided, the automatic mixing device includes: a bracket and a synchronous pulley shaft; the bracket at least comprises: the device comprises a first vertical plate and a synchronous pulley mounting frame arranged on the first vertical plate, wherein the synchronous pulley mounting frame comprises a first side wall, a second side wall and a bottom wall, the first side wall and the second side wall are oppositely arranged, the bottom wall is connected with the first side wall and the second side wall, and the first side wall, the bottom wall and the second side wall form a U-shaped structure; opposite ends of the synchronous pulley shaft are respectively arranged on the first side wall and the second side wall, and the first side wall is fixedly arranged on the first vertical plate.
Compared with the prior art, the automatic mixing device has the following beneficial effects:
Different from the condition of the prior art, the automatic mixing device comprises a first vertical plate and a synchronous pulley mounting frame, wherein two opposite ends of a synchronous pulley shaft are respectively arranged on a first side wall and a second side wall, and the first side wall is fixedly arranged on the first vertical plate. When synchronous pulley installs at this synchronous pulley mounting bracket, synchronous pulley's both sides are by synchronous pulley mounting bracket's first lateral wall and second lateral wall centre gripping, at automatic blending device during operation, the hold-in range is difficult for droing from synchronous pulley, and synchronous pulley also is difficult not hard up or drops, effectively improves the stability and the reliability of device simultaneously, simple structure simultaneously, the maintenance of being convenient for.
In order to solve the technical problems, the application adopts a technical scheme that: there is provided a sample analyzer comprising: the automatic mixing device and the sampling device are used for sampling the samples uniformly mixed by the automatic mixing device.
Compared with the prior art, the sample analyzer provided by the application has the following beneficial effects:
Different from the situation of the prior art, the sample analyzer comprises an automatic mixing device, wherein the automatic mixing device comprises a first vertical plate and a synchronous pulley mounting frame, opposite ends of a synchronous pulley shaft are respectively arranged on a first side wall and a second side wall, and the first side wall is fixedly arranged on the first vertical plate. When synchronous pulley installs at this synchronous pulley mounting bracket, synchronous pulley's both sides are by synchronous pulley mounting bracket's first lateral wall and second lateral wall centre gripping, at automatic blending device during operation, the hold-in range is difficult for droing from synchronous pulley, and synchronous pulley also is difficult not hard up or drops, effectively improves the stability and the reliability of device simultaneously, simple structure simultaneously, the maintenance of being convenient for.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present application, the drawings that are needed in the embodiments will be briefly described below, it being understood that the following drawings only illustrate some embodiments of the present application and should not be considered as limiting the scope, and other related drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
Fig. 1 is a first schematic structural view of a first embodiment of an automatic blending apparatus according to an embodiment of the present application;
fig. 2 is a schematic partial structure of a second embodiment of an automatic blending device according to an embodiment of the present application;
Fig. 3 is a schematic partial structure of a third embodiment of an automatic blending device according to an embodiment of the present application;
fig. 4 is a schematic partial structure of a fourth embodiment of an automatic blending apparatus according to an embodiment of the present application;
fig. 5 is a schematic partial structure of a fifth embodiment of an automatic blending apparatus according to an embodiment of the present application;
Fig. 6 is a schematic partial structure of a sixth embodiment of an automatic blending apparatus according to the present application;
fig. 7 is a schematic partial structure of a seventh embodiment of an automatic blending apparatus according to the present application;
Fig. 8 is a schematic partial structure of an eighth embodiment of an automatic blending apparatus according to an embodiment of the present application.
Detailed Description
The following description of the embodiments of the present application will be made clearly and fully with reference to the accompanying drawings, in which it is evident that the embodiments described are only some, but not all embodiments of the application. The components of the embodiments of the present application generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations. Thus, the following detailed description of the embodiments of the application, as presented in the figures, is not intended to limit the scope of the application, as claimed, but is merely representative of selected embodiments of the application. All other embodiments, which can be made by a person skilled in the art without making any inventive effort, are intended to fall within the scope of the present application.
In the description of the present application, it should be noted that the directions or positional relationships indicated by the terms "center", "upper", "lower", "left", "right", "vertical", "inner", "outer", etc. are based on the directions or positional relationships shown in the drawings, are merely for convenience of describing the present application and simplifying the description, and do not indicate or imply that the apparatus or elements referred to must have a specific orientation, be structured and operated in a specific orientation, and thus should not be construed as limiting the present application. Furthermore, the terms "first," "second," and "third" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance.
In the description of the present application, it should be noted that, unless explicitly specified and limited otherwise, the terms "mounted," "connected," and "connected" are to be construed broadly, and may be either fixedly connected, detachably connected, or integrally connected, for example; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present application will be understood in specific cases by those of ordinary skill in the art.
Embodiments of the present application provide an automated mixing device 10 that may be used for mixing micro-samples, such as tip samples.
As shown in fig. 1, the automatic blending device 10 includes a support 11, a Z-direction lifting mechanism 12, an X-direction horizontal feeding mechanism 13, and a blending mechanism 14, where the Z-direction lifting mechanism 12 and the X-direction horizontal feeding mechanism 13 are disposed on the support 11, and the Z-direction lifting mechanism 12 is used to drive the blending mechanism 14 to perform a vertical lifting motion in the Z-direction. The X-direction horizontal feeding mechanism 13 is used for driving the mixing mechanism 14 to perform linear horizontal movement in the X direction. The mixing mechanism 14 is used for driving the test tube 200to perform swinging motion so as to mix the sample in the test tube 200.
As can be seen from the above description and the description of fig. 1, the Z-direction lifting mechanism 12 and the X-direction horizontal feeding mechanism 13 are linked with the mixing mechanism 14, and the mixing mechanism 14 can be driven by the Z-direction lifting mechanism 12 or the X-direction horizontal feeding mechanism 13 to perform a vertical lifting motion in the Z-direction or a linear horizontal motion in the X-direction, so as to drive the clamping assembly 147 of the mixing mechanism 14 to move to a target position, and the clamping assembly 147 is aligned with the center of the test tube 200, so as to accurately clamp the test tube 200. The mixing mechanism 14 is used for driving the test tube 200 to perform swinging motion so as to realize automatic mixing of samples in the test tube 200.
According to the automatic mixing device 10 disclosed by the embodiment of the application, the mixing mechanism 14 can perform vertical lifting motion in the Z direction under the drive of the Z-direction lifting mechanism 12; the mixing mechanism 14 can perform linear horizontal movement in the X direction under the drive of the X-direction horizontal feeding mechanism 13; this structure is favorable to snatching by the centre gripping thing (for example test tube 200) when, control mixing mechanism 14 removes target position, guarantees that test tube 200 gets into the centre gripping subassembly 147 of mixing mechanism 14 smoothly, simultaneously, mixing mechanism 14 drive test tube 200 is the swing motion to be convenient for carry out abundant mixing to the sample is automatic, need not manual handling, uses manpower sparingly and time cost, and test tube 200 grabs and puts and mixing precision is higher, improves detection efficiency.
As shown in fig. 1-2, in one embodiment, the bracket 11 includes a first upright 111, a second upright 112, a first transverse 113, and a second transverse 114 that are connected end-to-end in sequence. The first vertical plate 111 and the second vertical plate 112 have an "L" structure, the first vertical plate 111, the second vertical plate 112, and the first transverse plate 113 have a "U" structure, and the first vertical plate 111, the second vertical plate 112, the first transverse plate 113, and the second transverse plate 114 have a "port" structure.
The bracket 11 further includes a bottom plate 1122 and a top plate 1123 disposed on opposite sides of the second riser 112, and the bottom plate 1122, the second riser 112, and the top plate 1123 are in a "U" shaped structure. The bottom plate 1122 and the top plate 1123 are respectively formed by horizontally bending opposite ends of the second vertical plate 112, and the bottom plate 1122 and the top plate 1123 are respectively connected to opposite ends of the first vertical plate 111. It should be noted that the number of the substrates,
Preferably, the bottom plate 1122 and the top plate 1123 are welded to opposite ends of the first vertical plate 111, respectively, to obtain the bracket 11 formed by bending the second vertical plate 112 and welded to the first vertical plate 111 into an integral structure, so as to ensure that the bracket 11 is structurally stable to provide reliable support
The bottom and top plates 1122, 1123 are substantially perpendicular to 1121, and the bottom and top plates 1122, 1123 are each substantially perpendicular to the first and second vertical plates 111, 113, 114.
The stand 11 further includes: a first extension plate 117 and a second extension plate 118 extending vertically from the second vertical plate 112, wherein the second extension plate 118 is substantially perpendicular to the first extension plate 117, and the second extension plate 118 is substantially parallel to the first vertical plate 111, and the first vertical plate 111 and the second extension plate 118 are respectively connected to opposite sides of the top plate 1123.
Preferably, the first vertical plate 111 and the second extending plate 118 are welded to opposite sides of the top plate 1123, respectively, so as to obtain the bracket 11 formed by vertically extending the second vertical plate 112 and welded to the first vertical plate 111 and the top plate 1123 into an integral structure, which can ensure that the bracket 11 is structurally stable to provide reliable support.
The second extension plate 118 is used to lock and fix to the rack of the apparatus, for example, the second extension plate 118 is locked and fixed to the rack of the Z-direction motor 121, and the first extension plate 117 also has a limiting and reinforcing effect on the second extension plate 118.
As shown in fig. 3, in an embodiment, the bracket 11 is provided with a synchronous pulley mounting frame 115, where the synchronous pulley mounting frame 115 includes a first side wall 1151, a bottom wall 1152 and a second side wall 1153 that are sequentially connected end to end, and the first side wall 1151, the bottom wall 1152 and the second side wall 1153 are in a "U" structure, and the first side wall 1151 is mounted on the first riser 111. The bottom wall 1152 is fixedly mounted to the bottom plate 1122 of the second riser 112. Specifically, the first sidewall 1151 may be fixedly mounted on the first vertical plate 111 by screws or an adhesive.
In one embodiment, the bottom wall 1152 is provided with a gourd hole (not shown), the bottom plate 1122 of the second vertical plate 112 is provided with a fixing member 1125, and the fixing member 1125 includes a head portion, a stud 11242, and a connecting portion connecting the head portion and the stud, wherein the head portion has a diameter smaller than a major hole diameter of the gourd hole and larger than a minor hole diameter of the gourd hole, and the connecting portion has a diameter smaller than a minor hole diameter of the gourd hole 1150. The head of the securing member 1125 passes through the large aperture of the gourd aperture and interferes with the small aperture of the gourd aperture to mount the bottom wall 1152 to the bottom plate 1122 of the second riser 112.
During installation, the fixing piece 1125 is inserted into the gourd hole from the large hole of the gourd hole, the synchronous pulley mounting frame 115 is moved, the fixing piece 1125 is driven to enter the small hole of the gourd hole, clamping connection between the fixing piece 1125 and the gourd hole is achieved, and further rapid installation of the synchronous pulley mounting frame 115 and the second vertical plate 112 is achieved, and time and labor are saved.
Preferably, the first side wall 1151, the bottom wall 1152 and the second side wall 1153 are integrally formed, and the first side wall 1151 and the second side wall 1153 are formed by bending the bottom wall 1152. Specifically, one end of the bottom wall 1152 extends outwardly and is bent to form a first side wall 1151 perpendicular to the bottom wall 1152. While the other end of the bottom wall 1152 extends outwardly and is bent to form a second side wall 1153 perpendicular to the bottom wall 1152 and parallel to the first side wall 1151.
The automatic blending apparatus 10 further includes a timing pulley shaft 16, and opposite ends of the timing pulley shaft 16 are disposed on the first sidewall 1151 and the second sidewall 1153, respectively. Specifically, opposite ends of the timing pulley shaft 16 are respectively screwed to the first side wall 1151 and the second side wall 1153 of the timing pulley mount 115.
As shown in fig. 1 and 4, in a certain embodiment, a Z-motor base 116 is provided on the bracket 11, and the Z-motor base 116 is used for fixedly mounting a Z-motor 121. The Z-motor mount 116 may be of a sheet-metal construction. The Z-motor base 116 is a side plate, and the Z-motor base 116 is disposed on a side of the top plate 1123 of the second vertical plate 112 facing the bottom plate 1122, specifically, the Z-motor base 116 can be fixedly connected with the top plate 1123 through screws. The Z-motor base 116 has a through hole 1160 formed therein, and an output end of the Z-motor 121 passes through the through hole 1160.
As shown in fig. 1 and 3, in one embodiment, the Z-lift mechanism 12 includes: the Z-direction motor 121, the first timing pulley 122, the first timing belt 123, the first rail 124, the first guide rail (not shown), the first slider (not shown), the lever (not shown), and the driven block (not shown).
The Z-motor 121 is disposed on the top plate 1123 through the Z-motor base 116, wherein a through hole 1160 is formed in the Z-motor base 116, and an output end of the Z-motor 121 passes through the through hole 1160.
Preferably, the Z-direction motor 121 is located in a space surrounded by the second vertical plate 112, the top plate 1123, and the second extension plate 118. Specifically, the Z-direction motor 121 may also be fixedly mounted on the second riser 112, the top plate 1123, and the second extension plate 118 by screws. It can be appreciated that by limiting the Z-direction motor 121 in the space enclosed by the second vertical plate 112, the top plate 1123 and the second extension plate 118, the stability of the Z-direction motor 121 during operation can be enhanced.
Further, the top plate 1123 is folded with a reinforcing plate 1124 in the width direction thereof, and the reinforcing plate 1124 is substantially parallel to the second riser 112. The reinforcing plate 1124 is used to reinforce the top plate 1123 to prevent the top plate 1123 from being deformed by the gravity of the Z-motor 121.
The timing pulley shaft 16 is fitted with a first timing pulley 122, and the first timing pulley 122 is coaxial with the timing pulley shaft 16. The two ends of the first synchronous belt 123 are respectively sleeved on the output ends of the first synchronous belt pulley 122 and the Z-direction motor 121. It can be appreciated that, since the opposite ends of the pulley shaft 16 are mounted on the pulley mounting frame 115, and the first pulley 122 is sleeved on the pulley shaft 16, the two ends of the first pulley 122 are defined by the pulley mounting frame 115, so that the stability and the reliability of the first pulley 122 during operation can be enhanced, and the first pulley 123 is prevented from being loosened.
The first rail 124 and the first guide rail are disposed on the second riser 112, and the first rail 124 are disposed in parallel, the first rail 124 and the first rail are disposed longitudinally up and down in the Z direction, and the first slider is disposed on the first rail and is in sliding fit with the first rail. The first slide may have a hole structure (not shown) formed therein for insertion of the lever so that the lever is mounted on the first slide. The driven block is fixedly arranged on the driving lever, and the driving lever is connected with the Z-direction motor 121 through a first synchronous belt 123.
As shown in fig. 5, in a certain embodiment, the mixing mechanism 14 includes at least: the first slider 141, the upper fixing plate 142, the lower fixing plate 143, the mixing motor 144, the bearing block 145, the rotating block 146, and the clamping assembly 147, wherein the upper fixing plate 142 and the lower fixing plate 143 may be in an integrated structure.
The upper fixing plate 142 is slidably disposed on the first guide rail through the first slider 141, and the upper fixing plate 142 is fixedly connected to the receiving block, so as to connect the mixing mechanism 14 and the Z-direction lifting mechanism 12. The deflector rod is fixed with the first synchronous belt 123, and driven by the Z-direction motor 121, the deflector rod is driven by the first synchronous belt 123 to vertically lift along the first track 124 in the Z-direction, and the upper fixing plate 142 is driven by the deflector rod and the driven block to vertically lift along the first track in the Z-direction, so that the mixing mechanism 14 is vertically lifted in the Z-direction. Alternatively, the Z-direction motor 121 is a stepper motor, and the position of the shift lever is controlled by a combination of a switch and the pulse step number of the stepper motor.
As shown in fig. 1, 6 and 8, in a certain embodiment, the automatic blending device 10 further includes a cable 15, where the cable 15 includes a first section 151, a first bending portion 152, a second section 153, a second bending portion 154 and a third section 155 that are connected end to end, the bending direction of the first bending portion 152 and the bending direction of the second bending portion 154 are opposite, and the first section 151 and the second section 153 are longitudinally arranged up and down along the Z direction.
The first section 151 is disposed on the first riser 111, specifically, the first section 151 is disposed on a side of the first riser 111 remote from the second riser 112, i.e., outside the first riser 111.
Optionally, a plurality of fixing clasps 156 are provided on a side of the first vertical plate 111 away from the second vertical plate 112, and it should be noted that when there are more monofilaments of the cable 15, the first section 151 may be snapped into the plurality of fixing clasps 156, so that the first section 151 is fixed more firmly, and is prevented from falling off during the round trip movement.
The cable 15 is specifically a power cable of the mixing motor 144 or a data cable of the mixing mechanism 14, the end of the third section 155 is connected to the mixing motor 144 of the mixing mechanism 14, and the end of the third section 155 moves back and forth along with the mixing motor 144 in the Z direction.
Since the first section 151 of the cable 15 is disposed on the side of the first vertical plate 111 away from the first horizontal plate 113, the shrinkage and bending of the third section 155 of the cable 15 always faces the outside of the first vertical plate 111 when the blending motor 144 reciprocates in the Z direction, and does not interfere with other devices inside the first vertical plate 111 or with a sampling device (not shown) disposed on the side of the automatic blending apparatus 10 away from the first vertical plate 111.
Optionally, the first bending portion 152 and the second section 153 are also fixed on a side of the first vertical plate 111 away from the first transverse plate 113.
Optionally, the bracket 11 further includes a guide plate 119, where the guide plate 119 includes a mounting plate 1191 and a bending plate 1192 connected to the mounting plate 1191. The mounting plate 1191 is disposed on the first vertical plate 111 in a direction consistent with the first section 151 of the cable 15, and the bending plate 1192 is parallel to the second vertical plate 112 of the second vertical plate 112.
The second section 153 of the cable 15 extends along a side of the bending plate 1192 near the first section 151, or the second section 153 extends along a side of the bending plate 1192 far from the first section 151.
Since the second section 153 of the cable 15 extends along the bending plate 1192, the movable range of the second section 153 of the cable 15 is limited by the bending plate 1192, and the second section 153 of the cable 15 does not interfere with other devices inside the first vertical plate 111 or with a sampling device (not shown) disposed on a side of the automatic mixing apparatus 10 away from the first vertical plate 111 when the mixing motor 144 reciprocates in the Z direction.
As shown in fig. 5, in a certain embodiment, the X-direction horizontal feeding mechanism 13 includes: an X-direction motor 131, a sliding lead screw nut unit 132, a second guide rail 133, a second slider 134, a traversing substrate 135, and a second slider 136.
Wherein, the X-direction motor 131 is arranged on the first transverse plate 113, and optionally, the X-direction motor 131 is a screw motor. The second guide rail 133 is disposed on the second transverse plate 114, the sliding screw nut unit 132 is respectively connected with the X-direction motor 131 and the second slide carriage 134, the traverse base plate 135 is fixedly mounted on the second slide carriage 134 through the second slide block 136, and the traverse base plate 135 is slidably disposed on the second guide rail 133 through the second slide block 136, wherein the first guide rail is fixedly mounted on the traverse base plate 135. The sliding screw nut unit 132 is a pushing mechanism well known to those skilled in the art, and thus a specific structure thereof is not described herein.
The second slide carriage 134 is driven by the X-direction motor 131 and the sliding screw nut unit 132 to move horizontally along the second rail 133 in the X-direction, the traverse base plate 135 is driven by the second slide carriage 134 to move horizontally along the second rail 133 in the X-direction, and the fixing plate is driven by the traverse base plate 135 and the first rail to move horizontally along the second rail 133 in the X-direction, so as to drive the clamping assembly 147 of the blending mechanism 14 to move horizontally in the X-direction.
Specifically, under the driving of the X-direction motor 131, the sliding lead screw nut unit 132 drives the second slider 134 to perform the linear horizontal movement along the second guide rail 133 in the X-direction, and the second slider 134 drives the traverse substrate 135 to perform the linear horizontal movement along the second guide rail 133 in the X-direction, at this time, the first guide rail disposed on the traverse substrate 135 and the upper fixing plate 142 disposed on the first guide rail also perform the linear horizontal movement in the X-direction synchronously, so as to further drive the clamping assembly 147 of the blending mechanism 14 to perform the linear horizontal movement in the X-direction, where the clamping assembly 147 performs the capturing or releasing of the test tube 200 during the linear horizontal movement in the X-direction.
Optionally, the X-direction motor 131 is a linear motor, and the movement of the mixing mechanism 14 is performed by a horizontal feeding manner. Specifically, in the embodiment of the present application, the mixing mechanism 14 firstly performs horizontal feeding to drive the motor 131 from its ready position, and the sliding screw-nut mechanism of the motor 131 drives the traversing base plate 135 and the upper fixing plate 142 to horizontally feed to a suitable position in the direction of the test tube rack (not shown), and synchronously feeds all the associated components and parts mounted on the upper fixing plate 142, and the suitable position for feeding is the center of the test tube rack and the center of the lifted test tube 200.
In a certain embodiment, the mixing motor 144 is disposed at an upper end of the upper fixing plate 142, and the lower fixing plate 143 is disposed at a lower end of the upper fixing plate 142. The detection element 1491 and the rotation block 146 are coaxially provided to the lower fixed plate 143, and the detection element 1491 and the rotation block 146 are rotated in synchronization.
Specifically, the bearing seat 145 is disposed through one end of the lower fixing plate 143 away from the upper fixing plate 142, one end of the bearing seat 145 is provided with a photoelectric switch 1492 and a detection element 1491, the photoelectric switch 1492 is electrically connected with the detection element 1491, and the other end of the bearing seat 145 is provided with a rotation block 146.
The detection element 1491 may be a photosensor or a correlation optocoupler. The detection element 1491 is used to sense the swing position of the rotating block 146.
Specifically, the detecting element 1491 is configured to detect whether the test tube 200 returns to the initial angle before mixing after mixing is completed.
It will be appreciated that when the mixing of the sample in the test tube 200 is completed, the test tube 200 needs to be replaced on the test tube rack for the next step, and if the test tube 200 does not return to the initial angle before mixing, the test tube 200 may not be placed on the test tube rack due to incorrect angle, so the detection element 1491 in the embodiment can improve the accuracy of the placement position of the test tube 200.
Optionally, the detecting element 1491 is further configured to detect whether the mixing mechanism 14 moves to the grippable position during the process of driving the mixing mechanism 14 by the Z-direction lifting mechanism 12, so as to prevent risk of a gripping failure or a breaking of the test tube 200 when the mixing mechanism 14 does not move to the grippable position.
Optionally, the detecting element 1491 is further configured to detect whether the test tube 200 moves to a position that is separated from the rack and is swingable during the process of driving the test tube 200 to be separated from the rack by the X-direction horizontal feeding mechanism 13.
As shown in fig. 5 and 7, to prevent the rotation block 146 from excessively swinging to cause interference or even scratch damage of the test tube 200 with other components of the sample analyzer, in one embodiment, the mixing mechanism 14 further includes a stopper 148, where the stopper 148 is disposed on the lower fixed plate 143, and the stopper 148 is used to limit the swinging angle of the rotation block 146 during the swinging of the rotation block 146.
In an embodiment, the stopper 148 is disposed on one side of the lower fixing plate 143 and adjacent to the detecting element 1491, and the stopper 148 is used to limit the swinging angle of the detecting element 1491 during the swinging process of the detecting element 1491, and since the rotating block 146 and the detecting element 1491 are coaxially disposed and synchronously swing, the swinging angle of the rotating block 146 can be limited. Specifically, when the stopper 148 is provided on the left side of the detection element 1491, the detection element 1491 can swing only toward the right side thereof, and the swing angle with respect to the initial vertical position is less than or equal to 135 °.
In one embodiment, a stopper 148 is disposed at one side of the lower fixing plate 143 and adjacent to the rotation block 146, and the stopper 148 is used to limit the swing angle of the rotation block 146 during the swing of the rotation block 146. Specifically, when the stopper 148 is provided on the right side of the rotation block 146, the rotation block 146 can swing only toward the left side thereof, and the swing angle with respect to the initial vertical position is less than or equal to 135 °.
Preferably, the stop 148 is positioned adjacent to one side of the sampling device to prevent the cuvette 200 from striking the sampling device or other device during mixing.
In some embodiments, the stop 148 is any one of a rectangular plate, an L-shaped plate, a cylindrical bar, or a tapered bar.
Preferably, the stop 148 includes a mounting plate 1481 and a stop plate 1482 connected to the mounting plate 1481, the mounting plate 1481 being secured to the lower mounting plate 143, the stop plate 1482 being disposed perpendicular to the mounting plate 1481, i.e., the mounting plate 1481 and the stop plate 1482 are in an "L" configuration.
Optionally, the mounting plate 1481 and the stop plate 1482 are of unitary construction.
In some embodiments, mounting plate 1481 is integrally formed with lower stationary plate 143.
In some embodiments, a first mounting hole is formed in mounting plate 1481 and a second mounting hole is formed in lower stationary plate 143 in communication with the first mounting hole. The first and second mounting holes are provided with fasteners 1483 therethrough to fix the mounting plate 1481 to the lower fixing plate 143.
In one embodiment, a clamping assembly 147 is disposed on the rotating block 146, the clamping assembly 147 including a base (not shown), a first jaw (not shown) and a second jaw (not shown), an elastic member (not shown), a shaft (not shown), a flexible member (not shown), a stop member (not shown), a cover plate (not shown), and a baffle plate (not shown).
The first clamping jaw comprises a first acting portion and a first clamping portion, and the first acting portion and the first clamping portion are respectively located on two sides of the hinge shaft. The second clamping jaw comprises a second acting part and a second clamping part, and the first acting part and the first clamping part are respectively positioned at two sides of the hinge shaft. The first action part and the second action part are arranged oppositely, and the first clamping part and the second clamping part are arranged oppositely.
Specifically, the surfaces of the first clamping portion and the second clamping portion, which are close to each other, have a recessed structure for accommodating the object to be clamped. The concave structure forms a clamping space, is favorable for increasing the contact surface between the clamping part and the clamped object, so as to improve the clamping stability, disperse the pressure of the clamping part on the clamped object and reduce the damage and deformation probability of the clamped object.
The first clamping part and the second clamping part are provided with an everting structure at one ends far away from the base, and the two everting structures are matched to form an opening-shaped structure for guiding when taking objects, so that the objects to be clamped can enter the clamping assembly 147 conveniently. Specifically, one end of the everting structure is connected with one clamping portion, the other end extends away from the other clamping portion, and the two everting structures are mutually matched to form an opening-shaped structure which is outwards relative to the clamping assembly 147. This structure is advantageous in that it plays a guiding role when gripping the object to be gripped (such as test tube 200), ensuring that test tube 200 smoothly enters gripping assembly 147.
The elastic piece is used for generating elastic force which enables the first acting part and the second acting part to be relatively far away, so that the first clamping jaw and the second clamping jaw respectively rotate relative to the base and drive the first clamping part and the second clamping part to be close to each other to generate clamping force so as to clamp the clamped object.
Optionally, the elastic component is a torsion spring, the torsion spring is sleeved on the first shaft body, and two force arms of the torsion spring are respectively abutted with the first action part and the second action part so as to act on the first action part and the second action part by elastic force. Because the first hinging position, the second hinging position and the third connecting position are in a triangular position relation, the torsion spring is more stable in connection with the first action part and the second action part, and the clamping safety is improved.
Different from the condition of the prior art, the automatic mixing device comprises a first vertical plate and a synchronous pulley mounting frame, wherein two opposite ends of a synchronous pulley shaft are respectively arranged on a first side wall and a second side wall, and the first side wall is fixedly arranged on the first vertical plate. When synchronous pulley installs at this synchronous pulley mounting bracket, synchronous pulley's both sides are by synchronous pulley mounting bracket's first lateral wall and second lateral wall centre gripping, at automatic blending device during operation, the hold-in range is difficult for droing from synchronous pulley, and synchronous pulley also is difficult not hard up or drops, effectively improves the stability and the reliability of device simultaneously, simple structure simultaneously, the maintenance of being convenient for.
According to a second aspect, another embodiment of the present application provides a sample analyzer, which includes the automatic mixing device 10, and further includes an automatic feeding device, where the automatic feeding device includes a base and a transmission assembly, a driving unit is fixed on the base, the transmission assembly is movably disposed on the base, the transmission assembly is connected to the body, the driving unit drives the transmission assembly to move relative to the base, and the transmission assembly drives the body to move the test tube rack to a preparation position for receiving the test tube 200.
A sample analyzer according to an embodiment of the present application includes an automatic feeding device and an automatic blending device 10. Firstly, the automatic feeding device comprises a base and a transmission assembly, the transmission assembly is driven by the driving unit to move, the body is driven to move by the movement of the transmission assembly, and the test tube rack is arranged on the body, so that the test tube rack can be moved to a preparation position for receiving the test tube 200, and the automatic feeding of the sample collection tube is realized. Secondly, under the drive of mixing motor 144, mixing motor 144 drives clamping assembly 147 rotary oscillation and vibration, because the test tube 200 that is equipped with the sample that waits to mix is held on the clamping jaw, the rotation and vibration of clamping assembly 147 can drive test tube 200 on the clamping jaw and do rotary oscillation and vibration to realize the purpose of automatic mixing sample, need not manual handling, use manpower sparingly and time cost, improve the work efficiency of trace sample mixing.
Different from the situation of the prior art, the sample analyzer comprises an automatic mixing device, wherein the automatic mixing device comprises a first vertical plate and a synchronous pulley mounting frame, opposite ends of a synchronous pulley shaft are respectively arranged on a first side wall and a second side wall, and the first side wall is fixedly arranged on the first vertical plate. When synchronous pulley installs at this synchronous pulley mounting bracket, synchronous pulley's both sides are by synchronous pulley mounting bracket's first lateral wall and second lateral wall centre gripping, at automatic blending device during operation, the hold-in range is difficult for droing from synchronous pulley, and synchronous pulley also is difficult not hard up or drops, effectively improves the stability and the reliability of device simultaneously, simple structure simultaneously, the maintenance of being convenient for.
While the application has been described in the specification and drawings with reference to a particular embodiment, it will be understood by those skilled in the art that various changes may be made and equivalents may be substituted for elements thereof without departing from the scope of the application as defined in the claims. Moreover, the combination and organization of features, elements, and/or functions between embodiments herein is clearly apparent, and thus, from this disclosure, one skilled in the art will recognize that features, elements, and/or functions of an embodiment may be optionally incorporated into another embodiment, unless otherwise described.
In addition, many modifications may be made to adapt a particular situation or material to the teachings of the application without departing from the essential scope thereof. Therefore, it is intended that the application not be limited to the particular embodiment illustrated by the drawings and described in the specification as the best mode presently contemplated for carrying out this application, but that the application will include all embodiments falling within the scope of the foregoing description and the appended claims.
Claims (9)
1. An automatic blending device, characterized in that the automatic blending device comprises: a bracket and a synchronous pulley shaft;
The bracket at least comprises: the synchronous pulley mounting frame comprises a first side wall, a second side wall and a bottom wall, wherein the first side wall and the second side wall are oppositely arranged, the bottom wall is connected with the first side wall and the second side wall, and the first side wall, the bottom wall and the second side wall form a U-shaped structure;
Opposite ends of the synchronous pulley shaft are respectively arranged on the first side wall and the second side wall, and the first side wall is fixedly arranged on the first vertical plate;
the automatic mixing device further comprises a Z-direction lifting mechanism, wherein the Z-direction lifting mechanism at least comprises a Z-direction motor, a first synchronous belt wheel and a first synchronous belt, the first synchronous belt wheel is sleeved on a synchronous belt shaft, and two ends of the first synchronous belt are respectively sleeved at the output ends of the first synchronous belt wheel and the Z-direction motor;
The automatic mixing device further comprises: the Z-direction lifting mechanism is used for driving the mixing mechanism to perform vertical lifting motion in the Z direction;
the cable comprises a first section, a first bending part, a second section and a second bending part which are connected end to end, wherein the first section is arranged on the first vertical plate, and the cable is a power cable connected with a mixing motor of the mixing mechanism or a data cable connected with the mixing mechanism;
The support is provided with a guide plate, the guide plate comprises a mounting plate and a bending plate connected with the mounting plate, the mounting plate is arranged on the first vertical plate and is consistent with the arrangement direction of the first section, and the second section is arranged along the bending plate in an extending way at one side close to the first section or along the bending plate in an extending way at one side far away from the first section;
the Z direction is the vertical direction of the horizontal plane under the geodetic coordinate system.
2. The automatic mixing device according to claim 1, wherein,
The first side wall, the bottom wall and the second side wall are of an integrated structure, and the first side wall and the second side wall are formed by bending the bottom wall.
3. The automatic mixing device according to claim 1, wherein,
The bracket further comprises: the top plate and the bottom plate are respectively formed by horizontally bending opposite ends of the second vertical plate, and are respectively connected with opposite ends of the first vertical plate;
Wherein, the diapire fixed mounting is on the bottom plate.
4. The automatic mixing device according to claim 3, wherein,
The bottom wall is provided with a calabash hole, the bottom plate is provided with a fixing piece, the fixing piece comprises a head part, a stud and a connecting part for connecting the head part and the stud, wherein the diameter of the head part is smaller than the large hole diameter of the calabash hole and larger than the small hole diameter of the calabash hole, and the diameter of the connecting part is smaller than the small hole diameter of the calabash hole;
the head of the fixing piece passes through the large hole of the hoist hole and interferes with the small hole of the hoist hole so as to mount the bottom wall on the bottom plate of the second vertical plate.
5. The automatic mixing device according to claim 3, wherein,
The bracket further comprises: the first extending plate and the second extending plate are formed by vertically extending the second vertical plate, wherein the second extending plate is approximately perpendicular to the first extending plate, the second extending plate is approximately parallel to the first vertical plate, and the first vertical plate and the second extending plate are respectively connected to two opposite sides of the top plate.
6. The automatic mixing device according to claim 5, wherein the Z-direction motor is disposed on the second vertical plate, and the timing belt shaft is disposed in parallel with an output end of the Z-direction motor;
The first timing pulley is coaxial with the timing pulley shaft.
7. The automatic mixing device according to claim 6, wherein,
The automatic mixing device further comprises: the Z-direction motor seat is provided with a through hole, wherein the Z-direction motor seat adopts a sheet-metal structure;
the Z-direction motor is arranged on the top plate through the Z-direction motor seat, and the output end of the Z-direction motor penetrates out of the through hole;
the Z-direction motor is positioned in a space surrounded by the second vertical plate, the top plate and the second extension plate.
8. The automatic mixing device according to claim 1, wherein,
The cable comprises a first bending part, a second bending part, a first section, a second section, a mixing motor, a mixing mechanism and a cable, wherein the first bending part is opposite to the second bending part in bending direction, the cable further comprises a third section, the head end of the third section is connected with the second bending part, the tail end of the third section is connected with the mixing motor of the mixing mechanism, and the tail end of the third section moves back and forth along with the mixing motor in the Z direction.
9. A sample analyzer, the sample analyzer comprising: the automatic mixing device according to any one of claims 1 to 8, and a sampling device for sampling a sample mixed by the automatic mixing device.
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| CN202010761305.XA CN114076708B (en) | 2020-07-31 | 2020-07-31 | Automatic mixing device and sample analyzer |
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