CN114072419A - 用于诊断人类和动物中活性田鼠巴贝虫和邓肯巴贝虫感染的新型分泌抗原 - Google Patents

用于诊断人类和动物中活性田鼠巴贝虫和邓肯巴贝虫感染的新型分泌抗原 Download PDF

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CN114072419A
CN114072419A CN202080049584.5A CN202080049584A CN114072419A CN 114072419 A CN114072419 A CN 114072419A CN 202080049584 A CN202080049584 A CN 202080049584A CN 114072419 A CN114072419 A CN 114072419A
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C·本马蒙
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Yale University
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Yale University
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    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56905—Protozoa
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/44—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from protozoa
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/20—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans from protozoa
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Microbiology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
CN202080049584.5A 2019-06-12 2020-06-12 用于诊断人类和动物中活性田鼠巴贝虫和邓肯巴贝虫感染的新型分泌抗原 Pending CN114072419A (zh)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201962860662P 2019-06-12 2019-06-12
US62/860,662 2019-06-12
US201962937645P 2019-11-19 2019-11-19
US62/937,645 2019-11-19
PCT/US2020/037500 WO2020252313A1 (en) 2019-06-12 2020-06-12 Novel secreted antigens for diagnosis of active babesia microti and babesia duncani infection in humans and animals

Publications (1)

Publication Number Publication Date
CN114072419A true CN114072419A (zh) 2022-02-18

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CN202080049584.5A Pending CN114072419A (zh) 2019-06-12 2020-06-12 用于诊断人类和动物中活性田鼠巴贝虫和邓肯巴贝虫感染的新型分泌抗原

Country Status (8)

Country Link
US (1) US20220236268A1 (https=)
EP (1) EP3983430A4 (https=)
JP (2) JP2022536679A (https=)
CN (1) CN114072419A (https=)
AU (1) AU2020292378A1 (https=)
BR (1) BR112021025089A2 (https=)
CA (1) CA3143027A1 (https=)
WO (1) WO2020252313A1 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119462946A (zh) * 2024-10-21 2025-02-18 华中农业大学 抗邓肯巴贝斯虫ald蛋白的单克隆抗体及其应用

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220341928A1 (en) * 2021-04-23 2022-10-27 Id-Fish Technology, Inc. Diagnosis of babesia using babesia recombinant proteins

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030091598A1 (en) * 2001-01-05 2003-05-15 Corixa Corporation Compounds and methods for the diagnosis and treatment of Babesia infection
US20090074783A1 (en) * 2007-09-14 2009-03-19 New York Blood Center Babesia subtilisin
CN104845981A (zh) * 2015-05-25 2015-08-19 中国疾病预防控制中心寄生虫病预防控制所 田鼠巴贝虫Bm1524抗原及其应用
CN108893476A (zh) * 2018-06-28 2018-11-27 中国疾病预防控制中心寄生虫病预防控制所 田鼠巴贝虫2d97抗原蛋白及其应用

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20180372742A1 (en) * 2015-12-10 2018-12-27 Immport Therapeutics, Inc. Babesia Biomarkers for Diagnostic and Screening In Vitro Diagnostic Test

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20030091598A1 (en) * 2001-01-05 2003-05-15 Corixa Corporation Compounds and methods for the diagnosis and treatment of Babesia infection
US20090074783A1 (en) * 2007-09-14 2009-03-19 New York Blood Center Babesia subtilisin
CN104845981A (zh) * 2015-05-25 2015-08-19 中国疾病预防控制中心寄生虫病预防控制所 田鼠巴贝虫Bm1524抗原及其应用
CN108893476A (zh) * 2018-06-28 2018-11-27 中国疾病预防控制中心寄生虫病预防控制所 田鼠巴贝虫2d97抗原蛋白及其应用

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN119462946A (zh) * 2024-10-21 2025-02-18 华中农业大学 抗邓肯巴贝斯虫ald蛋白的单克隆抗体及其应用

Also Published As

Publication number Publication date
AU2020292378A1 (en) 2022-01-06
JP2025186283A (ja) 2025-12-23
CA3143027A1 (en) 2020-12-17
EP3983430A4 (en) 2023-10-11
JP2022536679A (ja) 2022-08-18
EP3983430A1 (en) 2022-04-20
WO2020252313A1 (en) 2020-12-17
US20220236268A1 (en) 2022-07-28
BR112021025089A2 (pt) 2022-02-15

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Application publication date: 20220218