CN114062690A - Detection device - Google Patents
Detection device Download PDFInfo
- Publication number
- CN114062690A CN114062690A CN202111386459.6A CN202111386459A CN114062690A CN 114062690 A CN114062690 A CN 114062690A CN 202111386459 A CN202111386459 A CN 202111386459A CN 114062690 A CN114062690 A CN 114062690A
- Authority
- CN
- China
- Prior art keywords
- box body
- sampling
- reagent
- groove
- quantitative
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
Images
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/726—Devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/75—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated
- G01N21/77—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator
- G01N21/78—Systems in which material is subjected to a chemical reaction, the progress or the result of the reaction being investigated by observing the effect on a chemical indicator producing a change of colour
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N2001/002—Devices for supplying or distributing samples to an analysing apparatus
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Physics & Mathematics (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Hematology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Urology & Nephrology (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plasma & Fusion (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
The invention relates to a detection device, which comprises a box body and a cover cap buckled at the upper end of the box body, wherein a reagent box is arranged in the cover cap, a sampling puncture device is arranged at the top of the box body, a test strip is arranged in the box body, and after the reagent box is punctured, a reagent and the test strip are in contact reaction; when the device is used, a sampling puncture device can be used for sampling, then the cover cap is buckled on the box body, the sample and the reagent can be mixed, the mixed reagent can react with the test paper strip, the mixed reagent does not need to be dropped onto the test paper strip manually, the whole operation step is simple and convenient, and the reagent does not need to be spilled outside to pollute the environment.
Description
Technical Field
The invention belongs to the field of medical detection equipment, and particularly relates to a detection device.
Background
Hemoglobin in feces, also called fecal occult blood, is currently regarded as one of tumor markers of rectal cancer and colon cancer in clinic and is also a very useful diagnostic index. Fecal occult blood is an early warning of digestive tract abnormalities, and when the amount of bleeding is low, the appearance of the feces may not change abnormally and cannot be recognized by the naked eye. Therefore, for suspected patients with chronic hemorrhage of the digestive tract, fecal hematophagy examination should be performed, which is of great significance for early screening of malignant tumors of the digestive tract.
The utility model discloses a kit for short-term test hemoglobin in excrement and urine is disclosed, including upper cover plate, test paper strip, burette and lower apron, the upper cover plate is equipped with window and sample mouth, be equipped with sample treatment pad, colloidal gold on the test paper strip and combine pad, nitrocellulose membrane, pad and viscidity bottom plate that absorbs water, be equipped with the detection zone on the nitrocellulose membrane, the detection zone includes quality control line and test wire, the sample mouth with the sample treatment pad corresponds, the window with the detection zone corresponds, the lower apron with the upper cover plate matching is fixed.
Further, as disclosed in the utility model publication No. CN211348253U, a test paper strip, a test card and a kit for fecal occult blood are disclosed. The test strip comprises immunochromatography test paper and chemical test paper which are assembled together, at least the detection result observation area of the chemical test paper is overlapped with one end of the sample conduction pad, the detection result of the chemical test paper can be observed, and the other end of the sample conduction pad is contacted with the reagent sample loading area of the immunochromatography test paper.
It can be seen from the above two patents that the prior art needs the person to be tested to collect the feces, and needs to bring the feces to a professional detection mechanism, mix the reagent with the feces sample using a special sampling tool and a special container, and then suck the reagent onto a corresponding test strip or a corresponding detection card, which consumes time of the patient and the person to be tested, and easily causes leakage of the feces and the reagent to pollute the environment.
Disclosure of Invention
The invention aims to provide a detection device which is simple in operation steps and convenient to operate.
The technical scheme adopted by the invention is as follows:
the utility model provides a detection device, its includes the box body and detains the block in the box body upper end, is equipped with the kit in the block, is equipped with sample piercing depth at the top of box body, is equipped with the test paper strip in the box body is inside, and the reagent box is punctured the back, and reagent and test paper strip contact reaction.
Furthermore, a sealing film is arranged on the kit, and the sampling puncture device can puncture the sealing film.
Furthermore, the sampling puncture device comprises a sampling head which is fixedly arranged at the top of the box body and is approximately conical and a sampling groove which is arranged at the upper end position of the sampling head.
Furthermore, the sampling groove is a circular ring groove or a spiral groove and is arranged on the outer wall of the sampling head.
Furthermore, a liquid passing groove is arranged on the side wall of the sampling head and below the sampling groove.
Furthermore, the top surface of the box body is funnel-shaped, the sampling puncture device is fixedly arranged in the top surface, and the bottom of the top surface is provided with a liquid leakage hole for the downward flow of the reagent.
Furthermore, a columnar bulge or an intermittent rib is arranged on the funnel slope of the top surface.
Further, be equipped with quantitative pond in the box body, the top intercommunication of quantitative pond through runner and box body, reagent passes through the runner and enters into quantitative pond in, the one end of surveying the test paper strip is located quantitative pond.
Furthermore, an overflow hole is formed in the quantitative pool, and absorbent cotton is arranged in the overflow hole.
Furthermore, a slope surface is arranged above the quantitative pool, so that the bottom surface of the quantitative pool protrudes out of the bottom surface of the flow channel.
The invention has the positive effects that: when the device is used, a sampling puncture device can be used for sampling, then the cover cap is buckled on the box body, the sample and the reagent can be mixed, the mixed reagent can react with the test paper strip, the mixed reagent does not need to be dropped onto the test paper strip manually, the whole operation step is simple and convenient, and the reagent does not need to be spilled outside to pollute the environment.
Drawings
FIG. 1 is a schematic structural view of the present invention;
FIG. 2 is a schematic cross-sectional view of the present invention;
FIG. 3 is a schematic view of a quantification chamber according to the present invention;
FIG. 4 is a schematic view of a cover plate of the dosing tank of the present invention;
FIG. 5 is a cross-sectional view taken along line A-A of FIG. 4 in accordance with the present invention;
FIG. 6 is a schematic view of a pillar bump structure according to the present invention;
FIG. 7 is a schematic view of a flow channel of a quantification chamber according to the present invention.
In the attached figure, 1-box body, 2-cap, 3-kit, 4-sampling head, 5-liquid passing groove, 6-sampling groove, 7-conical tip, 8-top surface, 9-columnar bulge, 10-test paper strip, 11-flow channel, 12-overflow hole, 13-quantification pool, 15-quantification pool cover plate, 16-absorbent cotton, 17-slope surface, 18-baffle plate and 19-clip flow channel.
Detailed Description
In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures and detailed description thereof are described in detail below, wherein the detailed description is to be understood as an example of the present invention. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
Example 1
As shown in the attached figures 1-6, the invention comprises a box body 1 and a cap 2 buckled on the box body 1, a reagent box 3 is arranged in the cap 2, a sealing film is arranged on the reagent box 3, a sampling puncture device is arranged at the top of the box body 1, a test paper strip 10 is arranged in the box body 1, when the cap 2 covers the upper opening of the box body 1, the sampling puncture device can puncture the sealing film on the reagent box 3, and a sample extends into the reagent box 3 to be mixed with a reagent for reaction.
Preferably, the sampling puncture device comprises a sampling head 4 which is fixedly arranged at the top of the box body 1 and is approximately conical and a sampling groove 6 which is arranged on the outer side wall of the upper end of the sampling head 4, and the sampling groove 6 is arranged on the sampling head 4 in a circular or spiral shape. The membrane that seals of kit 3 adopts the aluminium membrane, after the membrane that seals is impaled to sampling head 4, stays the membrane outside through the scraping of membrane to the sampling head with the sample outside sampling groove 6, makes the sample formation ration in the sampling groove and the reagent reaction in the reagent box, and the sample mixes more accurately and is favorable to improving the detection accuracy, adopts this kind of mixed mode to operate also more simple and convenient simultaneously.
After the sampling puncture device is inserted into the sample, a part of the stool sample is left in the sampling groove 6, so that the sampling function is realized. After subsequent penetration into the cartridge 3, the sample is mixed with the reagents. The structure of the sampling groove 6 not only can realize the function of convenient sampling, but also can play a role of quantification approximately, so that more samples can not be taken, and the requirement of the sample amount for detection can still be met.
A conical tip 7 is arranged at the top of the sampling head 4.
In order to make the mixed reagent flow out smoothly, a liquid passing groove 5 is arranged on the side wall of the sampling head 4 and below the sampling groove 6, so that after the sampling head 4 penetrates into the sealing film, a gap is inevitably left between the sampling head 4 and the sealing film, and the reagent can flow out from the gap.
The top surface 8 of box body 1 is hopper-shaped, is convenient for collect liquid, and the bottom of sampling head 4 is fixed on top surface 8, and has opened the weeping hole in funnel bottom position, flows into box body 1 from the weeping hole in, then detects with surveying test paper strip 10 contact.
Example 2
The present embodiment is a further improvement on the basis of embodiment 1, a quantitative cell 13 is arranged in the box body 1, the quantitative cell 13 is communicated with a leakage hole on the top surface 8 of the box body 1 through a flow channel 11, the mixed reagent enters the quantitative cell 13 through the flow channel 11, and one end of the test paper strip 10 is positioned in the quantitative cell 13 and can be detected with the liquid in the quantitative cell 13.
In this embodiment, a partition board is arranged in the box body 1, the flow channel 11 and the quantitative pool 13 are both located on the same side of the partition board, an overflow hole 12 is formed in the quantitative pool 13 on the partition board, and the other side of the partition board is correspondingly provided with absorbent cotton 16 to absorb overflowed liquid and prevent the liquid from flowing to other places. Preferably, a slope 17 is formed on the partition above the quantitative pool so that the bottom surface of the quantitative pool 13 protrudes from the bottom surface of the flow channel 11.
Example 3
This embodiment is a further improvement on embodiments 1 and 2, as shown in fig. 2, 5 and 6, a cylindrical protrusion 9 or an intermittent rib is provided on the funnel slope of the top surface 8 for blocking the solid in the sample, so that the liquid entering into the box body 1 is not doped with the solid.
Example 4
In this embodiment, as shown in fig. 7, a dilution and uniform mixing flow channel is provided in the flow channel 11, and a fluid deceleration structure is connected to the bottom of the quantitative cell 13.
Specifically, the diluting and uniformly mixing flow channel comprises baffles 18 arranged on the left side wall and the right side wall of the liquid inlet flow channel, and two adjacent baffles 18 are sequentially and alternately arranged on the baffles 18 on the two sides along the liquid flowing direction.
The fluid deceleration structure comprises a clip-shaped flow channel 19, one end of the clip-shaped flow channel 19 is communicated with the quantification pool 13, and the other end is communicated with the test paper strip 10. Preferably, there are two loop-shaped flow paths 19, which are respectively disposed at the left and right sides of one end of the test strip 10.
In this embodiment, a diluting and uniformly mixing flow channel is arranged in the liquid inlet flow channel of the quantitative cell 13 and/or a fluid deceleration structure is arranged near the end of the test paper strip, the diluting and uniformly mixing flow channel is formed by baffles 18 which are alternately arranged left and right, the liquid needs a longer time in the process of flowing downwards into the quantitative cell 13, and the liquid can also play a role in accelerating mixing when impacting the baffles 18, so that the uniform mixing effect of the sample and the reagent is realized.
The fluid deceleration structure can also increase the flowing time of liquid, so that the sample and the reagent are fully and uniformly mixed, and meanwhile, the flow rate of the mixed liquid flowing onto the test paper strip is slowed down, so that the reagent and the sample are fully reacted.
In general, this embodiment not only serves to quantify the amount of the mixed solution, but also prevents the excessive mixed solution from reacting with the test strip 10. Meanwhile, by arranging the diluting and mixing flow channel and the fluid speed reducing structure, the sample and the reagent can be fully mixed, the contact speed of the mixed liquid and the detection paper strip is reduced, and the reagent and the sample can fully react.
When the kit is used, the sampling head 4 is dipped with a sample and pressed downwards into the cap, the sampling head 4 can puncture a sealing film of the kit and enter the kit, so that the sample is contacted with a reagent, and the sample is flushed into the reagent; then the whole integrated colloidal gold detection rod is inverted, reagents and samples in the kit can flow into a quantitative pool 13 in the box body through a liquid passing groove 5 on a sampling head 4 and a liquid flow passage in the box body, and redundant liquid can flow onto a water absorption cotton 16 through a liquid overflow hole 12 after the quantitative pool 13 is full; the liquid in the quantitative determination tank 13 is absorbed and reacted by the test paper strip.
The above examples are only intended to illustrate the technical solution of the present invention, but not to limit it; although the present invention has been described in detail with reference to the foregoing embodiments, it will be understood by those of ordinary skill in the art that: the technical solutions described in the foregoing embodiments may still be modified, or some technical features may be equivalently replaced; and such modifications or substitutions do not depart from the spirit and scope of the corresponding technical solutions of the embodiments of the present invention.
Claims (10)
1. The utility model provides a detection device, its characterized in that it includes box body (1) and detains lid (2) in box body (1) upper end, is equipped with kit (3) in lid (2), is equipped with sample piercing depth at the top of box body (1), is equipped with in box body (1) inside and surveys test paper strip (10), and after kit (3) were punctured, reagent and survey test paper strip (10) contact reaction.
2. The test device according to claim 1, characterized in that a sealing membrane is provided on the reagent cartridge (3) and the sampling puncture device can puncture the sealing membrane.
3. The detecting device according to claim 1 or 2, characterized in that the sampling puncturing device comprises a sampling head (4) which is fixedly arranged at the top of the box body (1) and is approximately conical, and a sampling groove (6) which is arranged at the upper end position of the sampling head (4).
4. The detection device according to claim 3, characterized in that the sampling groove (6) is an annular groove or a spiral groove formed on the outer wall of the sampling head (4).
5. The detecting device according to claim 3, characterized in that the liquid passing groove (5) is arranged on the side wall of the sampling head (4) and below the sampling groove (6).
6. The testing device according to claim 1, wherein the top surface (8) of the cartridge body (1) is funnel-shaped, the sampling puncturing device is fixedly installed in the top surface (8), and a liquid leakage hole is formed at the bottom of the top surface (8) for the downward flow of the reagent.
7. A testing device according to claim 6, characterized in that on the funnel slope of the top surface (8) there are provided stud bumps (9) or intermittent ribs.
8. The detection device according to claim 1, wherein a quantitative pool (13) is arranged in the box body (1), the quantitative pool (13) is communicated with the top of the box body (1) through a flow channel (11), a reagent enters the quantitative pool (13) through the flow channel (11), and one end of the test strip (10) is positioned in the quantitative pool (13).
9. The detecting device according to claim 8, characterized in that an overflow hole (12) is formed in the quantitative determination reservoir (13), and a water absorbent cotton (16) is provided in the overflow hole (12).
10. The detecting device according to claim 9, wherein a slope (17) is formed above the quantifying reservoir (13) so that the bottom surface of the quantifying reservoir (13) protrudes from the bottom surface of the flow path (11).
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111386459.6A CN114062690A (en) | 2021-11-22 | 2021-11-22 | Detection device |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN202111386459.6A CN114062690A (en) | 2021-11-22 | 2021-11-22 | Detection device |
Publications (1)
Publication Number | Publication Date |
---|---|
CN114062690A true CN114062690A (en) | 2022-02-18 |
Family
ID=80278886
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN202111386459.6A Withdrawn CN114062690A (en) | 2021-11-22 | 2021-11-22 | Detection device |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN114062690A (en) |
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN115629064A (en) * | 2022-11-30 | 2023-01-20 | 神州医疗科技股份有限公司 | Sampling and detection integrated device and control method thereof |
WO2023201671A1 (en) * | 2022-04-22 | 2023-10-26 | 宁德时代新能源科技股份有限公司 | Measurement assembly and manufacturing method therefor, and measurement apparatus and measurement system |
WO2024087868A1 (en) * | 2022-10-26 | 2024-05-02 | 石家庄禾柏生物技术股份有限公司 | Integrated sampling sealing kit |
-
2021
- 2021-11-22 CN CN202111386459.6A patent/CN114062690A/en not_active Withdrawn
Cited By (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2023201671A1 (en) * | 2022-04-22 | 2023-10-26 | 宁德时代新能源科技股份有限公司 | Measurement assembly and manufacturing method therefor, and measurement apparatus and measurement system |
WO2024087868A1 (en) * | 2022-10-26 | 2024-05-02 | 石家庄禾柏生物技术股份有限公司 | Integrated sampling sealing kit |
CN115629064A (en) * | 2022-11-30 | 2023-01-20 | 神州医疗科技股份有限公司 | Sampling and detection integrated device and control method thereof |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN114062690A (en) | Detection device | |
CN110366682B (en) | Fecal sampling and occult blood detection integrated device | |
EP3926322A1 (en) | Integrated device for medical sampling and testing | |
CN108348913A (en) | Lateral flow assay device and method | |
CN107036848A (en) | The device that a kind of sample is collected and detected | |
WO2021027082A1 (en) | Sample collection and detection device and method | |
CN115201469A (en) | Detection device | |
CN115372615A (en) | Detection device | |
CN208140386U (en) | Fecal sample integral collecting device | |
CN219201612U (en) | Medical detection device capable of being integrated for in-vitro diagnosis | |
CN113049813A (en) | Closed self-checking device for gastrointestinal occult blood | |
WO2018068377A1 (en) | Liquid sample guiding device and test apparatus comprising same | |
CN212255361U (en) | Sample detection device | |
CN218445531U (en) | Detection box for medical detection | |
CN217305198U (en) | Two joint inspection reagent card | |
CN215492506U (en) | A dilute mixed cabin structure for shit detects | |
CN212255360U (en) | Solid-state sample detection device | |
CN216696342U (en) | Quantitative pool with speed reduction flow channel | |
CN218496476U (en) | Sampling and detecting integrated device | |
KR101635956B1 (en) | Diagnostic kit having puncturing element | |
CN114660281A (en) | Prepackaged test paper detection cup and detection method thereof | |
CN209772147U (en) | Centrifugal micro-fluidic chip | |
CN212255362U (en) | Liquid sample detection device | |
CN206847995U (en) | Applicator | |
CN214310535U (en) | Stool dilution sampling mechanism for stool detection |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
WW01 | Invention patent application withdrawn after publication |
Application publication date: 20220218 |
|
WW01 | Invention patent application withdrawn after publication |