CN114028838A - Bio-pharmaceuticals extraction separator - Google Patents
Bio-pharmaceuticals extraction separator Download PDFInfo
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- CN114028838A CN114028838A CN202111413725.XA CN202111413725A CN114028838A CN 114028838 A CN114028838 A CN 114028838A CN 202111413725 A CN202111413725 A CN 202111413725A CN 114028838 A CN114028838 A CN 114028838A
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- 238000000605 extraction Methods 0.000 title claims abstract description 87
- 229960000074 biopharmaceutical Drugs 0.000 title claims description 12
- 238000002156 mixing Methods 0.000 claims abstract description 58
- 238000000926 separation method Methods 0.000 claims abstract description 13
- 238000003756 stirring Methods 0.000 claims description 24
- 238000010438 heat treatment Methods 0.000 claims description 14
- 230000003014 reinforcing effect Effects 0.000 claims description 14
- 230000000149 penetrating effect Effects 0.000 claims description 10
- 239000007788 liquid Substances 0.000 claims description 6
- 239000003795 chemical substances by application Substances 0.000 description 9
- 238000013019 agitation Methods 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 238000000354 decomposition reaction Methods 0.000 description 2
- 238000004821 distillation Methods 0.000 description 2
- 241000894006 Bacteria Species 0.000 description 1
- 208000035473 Communicable disease Diseases 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 241000606701 Rickettsia Species 0.000 description 1
- 241000700605 Viruses Species 0.000 description 1
- 231100000659 animal toxin Toxicity 0.000 description 1
- -1 animal toxins Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 238000009833 condensation Methods 0.000 description 1
- 230000005494 condensation Effects 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- WABPQHHGFIMREM-UHFFFAOYSA-N lead(0) Chemical compound [Pb] WABPQHHGFIMREM-UHFFFAOYSA-N 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 239000011435 rock Substances 0.000 description 1
- 238000006467 substitution reaction Methods 0.000 description 1
- 230000001360 synchronised effect Effects 0.000 description 1
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D11/00—Solvent extraction
- B01D11/02—Solvent extraction of solids
- B01D11/0215—Solid material in other stationary receptacles
- B01D11/0253—Fluidised bed of solid materials
- B01D11/0257—Fluidised bed of solid materials using mixing mechanisms, e.g. stirrers, jets
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- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Extraction Or Liquid Replacement (AREA)
Abstract
The invention discloses a biological pharmacy extraction separation device, and relates to the technical field of biological pharmacy; the supporting blocks are respectively fixed on the left side and the right side of the upper side of the processing kettle body; the lifting electric push rods are respectively fixed on the corresponding supporting blocks; the support frame is arranged on the upper side of the processing kettle body, and the pushing end of the lifting electric push rod is connected with the bottom surface of the support frame; the connecting support blocks are symmetrically fixed at the front and the back of the bottom of the support frame, and the bottom of the connecting support block is fixed on the movable cover; the reciprocating driving mechanism is arranged between the front connecting support block and the rear connecting support block; the connecting support is arranged on the lower side of the movable cover and is arranged in the processing kettle body; the reinforced mixing mechanism is arranged between the connecting strut and the movable cover; the connecting frame is fixed at the bottom of the connecting support; the net rack is rotatably arranged inside the connecting rack through threads; the filter frame is fixed at the bottom of the net rack; can drive the extraction frame and carry out abundant rotation, make and treat that extraction solute carries out intensive mixing with the extractant, conveniently carry out extraction separation operation to the solute.
Description
Technical Field
The invention relates to the technical field of biological pharmacy, in particular to a biological pharmacy extraction separation device.
Background
Biopharmaceuticals refer to biological products processed from microorganisms (bacteria, rickettsia, viruses, etc.) and their metabolites, animal toxins, blood or tissues of human or animals, etc. for preventing, treating, and diagnosing corresponding infectious diseases or other related diseases; the operation of extraction separation needs to be adopted in the production process of bio-pharmaceuticals, and current extraction separation operation includes extraction, distillation and condensation, need heat during the distillation, and the phenomenon inhomogeneous, the slow heating of heating appears in the heating easily, and current bio-pharmaceuticals extraction separator is when carrying out the extraction operation, and the time that consumes is longer.
Disclosure of Invention
The invention aims to overcome the defects and shortcomings of the prior art, and provides a biopharmaceutical extraction separation device which is simple in structure, reasonable in design and convenient to use, can drive an extraction frame to rotate fully, enables solutes to be extracted to be fully mixed with an extractant, and facilitates extraction separation operations of the solutes.
In order to achieve the purpose, the invention adopts the technical scheme that: the processing kettle comprises a processing kettle body, wherein a door is arranged on the front side of the processing kettle body, and a movable cover is arranged on the upper side of the processing kettle body;
it also includes:
the two support blocks are respectively fixed on the left side and the right side of the upper side of the processing kettle body;
the two lifting electric push rods are respectively fixed on the corresponding supporting blocks and are connected with an external power supply;
the support frame is arranged in an inverted U-shaped structure, the support frame is arranged on the upper side of the processing kettle body, and the pushing end of the lifting electric push rod is connected with the bottom surface of the support frame;
the two connecting support blocks are symmetrically fixed at the bottom of the support frame in the front-back direction, and the bottoms of the connecting support blocks are fixed on the movable cover;
the reciprocating driving mechanism is arranged between the front connecting support block and the rear connecting support block;
the connecting support is arranged on the lower side of the movable cover and is arranged in the processing kettle body;
the reinforced mixing mechanism is arranged between the connecting support and the movable cover;
the connecting frame is fixed at the bottom of the connecting support;
the net rack is rotatably arranged inside the connecting rack through threads;
the filter frame is fixed at the bottom of the net rack;
the mixing frame is arranged inside the processing kettle body, arranged on the lower side of the connecting frame and connected with the processing kettle body through connecting pieces on the left side and the right side;
the guide frame is fixed on the inner bottom surface of the mixing frame and is in an inverted cone structure, and the upper side of the guide frame is connected with the inner annular wall of the mixing frame; a heating lamp is arranged on the outer ring wall of the guide frame; the heating lamp is connected with an external power supply;
the discharge pipe is arranged at the bottom of the mixing frame in a penetrating way, and an electromagnetic valve is arranged on the discharge pipe;
the extraction frame, the extraction frame arrange in the downside that mixes the frame, and the left and right sides of extraction frame all is fixed with support piece, support piece and the interior rampart of the processing cauldron body are connected.
Preferably, the reciprocating drive mechanism comprises:
the driving motor is fixed on the connecting support block at the rear side and is connected with an external power supply;
the driving gear is arranged between the front connecting support block and the rear connecting support block and is fixed on a front output shaft of the driving motor;
the two rotating gears are respectively meshed with the left side and the right side of the driving gear and are arranged in the front connecting support block and the rear connecting support block in a screwing manner through rotating shafts which are fixedly penetrated in the rotating gears;
the two reciprocating half gears are respectively arranged on the front sides of the corresponding rotating gears and are sleeved and fixed on the corresponding rotating shafts; the tooth directions of the left reciprocating half gear and the right reciprocating half gear are the same;
the reciprocating tooth block is arranged on the front side of the driving gear, the reciprocating tooth block is arranged between the left reciprocating half gear and the right reciprocating half gear, the reciprocating tooth block is fixed on the movable cover, reciprocating teeth are fixed on the left side and the right side of the reciprocating tooth block, and the reciprocating teeth are respectively movably meshed with the corresponding reciprocating half gears;
the guide block penetrates through the reciprocating moving toothed block, and the upper end of the guide block is fixed at the bottom of the support frame;
the driving motor makes the driving gear on its front side output, the driving gear rotates and meshes the running gear that drives the left and right sides respectively and carries out synchronous rotation, the running gear of both sides drives respective axis of rotation respectively and rotates, thereby make reciprocal half gear rotate, reciprocal half gear rotates respectively and the reciprocal tooth meshing on the reciprocating motion tooth piece that corresponds, thereby make reciprocating motion tooth piece drive movable cover carry out up-and-down reciprocating motion, then make the filter frame of downside reciprocate, it rocks to reciprocate in mixing the frame, thereby make extraction solute and extractant intensive mixing in the filter frame.
Preferably, the intensive mixing mechanism comprises:
the number of the reinforcing frames is two, and the reinforcing frames are arranged in an L-shaped structure; the two reinforcing frames are oppositely arranged and fixed at the bottom of the movable cover from left to right;
the rotating bracket is fixed between the left reinforcing frame and the right reinforcing frame; the connecting strut is screwed and penetrated in the rotating bracket through a bearing; a boss is fixed at the upper end of the connecting strut and is arranged at the upper side of the rotating bracket in a contact manner;
the driven gear is sleeved and fixed on the connecting strut;
the driving gear is meshed with the right side of the driven gear, and a support shaft is arranged in the driving gear in a penetrating way and is fixed;
the driving motor is fixed at the bottom of the movable cover, an output shaft of the driving motor is fixedly connected with the support shaft, and the driving motor is connected with an external power supply;
the driving motor is started to drive the driving gear to rotate, so that the driven gear rotates, the connecting support is rotated, the connecting frame on the lower side is driven to rotate the filter frame, and the extraction solute rotates in the extraction agent.
Preferably, a rotating motor is fixed in a groove at the bottom of the connecting frame, a stirring shaft is fixed on an output shaft at the bottom of the rotating motor, and the stirring shaft is arranged between the net rack and the filter frame in a penetrating way; the outer ring wall of the stirring shaft is sequentially fixed with stirring rods in equal number from top to bottom and in equal round angle distribution, and the stirring rod positioned at the lowest side is smaller than the stirring rod positioned at the upper side; the stirring rod is rotated by rotating the motor, so that the extraction solute in the filter frame is stirred in a rotating manner, and the extraction solute and the extractant in the extraction frame are fully mixed.
Preferably, the extraction frame is internally provided with a filter frame in a screwed connection manner through threads, a filter screen is arranged in the filter frame, a plurality of clamping frames are distributed and fixed at equal angles on the circumference of the upper side of the filter frame, the clamping frames are arranged in an inverted L-shaped structure, and the clamping frames are clamped on the extraction frame; the filter frame filters the extraction liquid flowing out of the upper discharge pipe.
The working principle of the invention is as follows: when the device is used, the support frame is driven upwards by the lifting electric push rods on the left side and the right side, so that the connecting support column drives the filter frame to be away from the mixing frame upwards, the door on the front side of the processing kettle body is opened manually, the net rack is unscrewed from the connecting frame, an extraction solute is placed in the filter frame, and then the net rack and the connecting frame are screwed down manually; meanwhile, an extracting agent is injected into the mixing frame and is heated by a heating lamp; the lifting electric push rods on the two sides push downwards at the same time, so that the support frame drives the movable cover and the connecting support column to move downwards until the movable cover is arranged inside the processing kettle body, and the filter frame is arranged in the mixing frame; the filter frame is driven in different modes by the reciprocating driving mechanism and the reinforced mixing mechanism to move in different ways in the mixing frame, so that the extraction solute in the filter frame and the extraction agent in the mixing frame are fully mixed, and the extraction liquid finally flows downwards into the extraction frame from the discharge pipe.
After adopting the structure, the invention has the beneficial effects that:
1. the reciprocating drive mechanism drives the movable cover to make the filter frame on the lower side reciprocate up and down in the mixing frame, so that the extraction solute is fully contacted with the extraction agent for decomposition;
2. the filter frame is driven by the reinforced mixing mechanism to rotate in the mixing frame, so that the extraction solute can rotate in the extractant, the two extractants can be in full contact, and the extraction quality is improved.
Drawings
In order to more clearly illustrate the embodiments of the present invention or the technical solutions in the prior art, the drawings used in the description of the embodiments or the prior art will be briefly described below, it is obvious that the drawings in the following description are only some embodiments of the present invention, and for those skilled in the art, other drawings can be obtained according to the drawings without creative efforts.
Fig. 1 is a schematic structural view of the present invention.
Fig. 2 is a top view of fig. 1.
Fig. 3 is a sectional view taken along line a-a in fig. 2.
Fig. 4 is an enlarged view of a portion B in fig. 3.
Fig. 5 is an enlarged view of the portion C in fig. 3.
Description of reference numerals:
the device comprises a processing kettle body 1, a door 1-1, a movable cover 1-2, a supporting block 2, a lifting electric push rod 3, a supporting frame 4, a connecting supporting block 5, a reciprocating driving mechanism 6, a driving motor 6-1, a driving gear 6-2, a rotating gear 6-3, a reciprocating half gear 6-4, a reciprocating gear block 6-5, a guide block 6-6, a connecting support 7, a boss 7-1, a reinforced mixing mechanism 8, a reinforced frame 8-1, a rotating frame 8-2, a driven gear 8-3, a driving gear 8-4, a driving motor 8-5, a connecting frame 9, a net frame 10, a filter frame 11, a mixing frame 12, a guide frame 13, a heating lamp 14, a discharging pipe 15, an extraction frame 16, a rotating motor 17, a stirring rod 18, a filter frame 19 and a clamping frame 20.
Detailed Description
The invention will be further described with reference to the accompanying drawings.
Referring to fig. 1 to 5, the technical solution adopted by the present embodiment is: the processing kettle comprises a processing kettle body 1, wherein a door 1-1 is arranged on the front side of the processing kettle body 1, one side of the door 1-1 is hinged with the processing kettle body 1 through a hinge, the other side of the door 1-1 is connected with the processing kettle body 1 through a hasp, and a movable cover 1-2 is arranged on the upper side of the processing kettle body 1;
it also includes:
the number of the supporting blocks 2 is two, and the two supporting blocks 2 are respectively fixed on the left side and the right side of the upper side of the processing kettle body 1 by screws;
the two lifting electric push rods 3 are respectively fixed on the corresponding supporting blocks 2 by screws, and the lifting electric push rods 3 are connected with an external power supply through leads; the specific use model of the lifting electric push rod 3 is directly purchased, installed and used from the market according to the actual use requirement;
the support frame 4 is arranged in an inverted U-shaped structure, the support frame 4 is arranged on the upper side of the processing kettle body 1, and the pushing end of the lifting electric push rod 3 is connected with the bottom surface of the support frame 4 through screws;
the two connecting support blocks 5 are symmetrically fixed at the bottom of the support frame 4 by screws, and the bottoms of the connecting support blocks 5 are fixed on the movable covers 1-2 by screws;
the reciprocating driving mechanism 6 is arranged between the front connecting support block 5 and the rear connecting support block 5;
the connecting support post 7 is arranged at the lower side of the movable cover 1-2, and the connecting support post 7 is arranged in the processing kettle body 1;
the reinforced mixing mechanism 8, the reinforced mixing mechanism 8 is arranged between the connecting strut 7 and the movable cover 1-2;
the connecting frame 9, the said connecting frame 9 is fixed to the bottom of the connecting strut 7 with the screw;
the net rack 10 is rotatably arranged inside the connecting rack 9 through threads;
the filter frame 11, the said filter frame 11 is fixed to the bottom of the net rack 10 with the screw;
the mixing frame 12 is arranged inside the processing kettle body 1, the mixing frame 12 is arranged at the lower side of the connecting frame 9, and the mixing frame 12 is connected with the processing kettle body 1 through connecting pieces at the left side and the right side by screws;
the guide frame 13 is fixed on the inner bottom surface of the mixing frame 12 by screws, the guide frame 13 is arranged in an inverted cone structure, and the upper side of the guide frame 13 is connected with the inner annular wall of the mixing frame 12 by screws; a heating lamp 14 is arranged on the outer ring wall of the guide frame 13; the heating lamp 14 is connected to an external power supply through a lead wire; the specific use model of the heating lamp 14 is directly purchased from the market and installed and used according to the actual use requirement;
the discharge pipe 15 is arranged at the bottom of the mixing frame 12 in a penetrating way, and an electromagnetic valve is arranged on the discharge pipe 15;
the extraction frame 16, the extraction frame 16 set up in the downside that mixes frame 12, and the left and right sides of extraction frame 16 all utilizes the screw fixation to have a support piece, support piece and the interior rampart of the processing kettle body 1 utilize screwed connection.
Preferably, the reciprocating driving mechanism 6 further comprises:
the driving motor 6-1 is fixed on the connecting support block 5 at the rear side by screws, and the driving motor 6-1 is connected with an external power supply through a lead; the specific use model of the driving motor 6-1 is directly purchased, installed and used from the market according to the actual use requirement;
the driving gear 6-2 is arranged between the front connecting support block 5 and the rear connecting support block 5, and the driving gear 6-2 is fixed on a front output shaft of the driving motor 6-1 by screws;
two rotating gears 6-3 are arranged, and are respectively meshed with the left side and the right side of the driving gear 6-2, and the rotating gears 6-3 are rotatably arranged in the front connecting support block 5 and the rear connecting support block 5 through rotating shafts fixedly penetrating in the rotating gears 6-3;
two reciprocating half gears 6-4 are arranged, and are respectively arranged at the front side of the corresponding rotating gear 6-3, and the reciprocating half gears 6-4 are sleeved and fixed on the corresponding rotating shafts; the tooth directions of the left reciprocating half gear 6 and the right reciprocating half gear 4 are the same;
the reciprocating gear block 6-5 is arranged on the front side of the driving gear 6-2, the reciprocating gear block 6-5 is arranged between the left reciprocating half gear 6-4 and the right reciprocating half gear 6-4, the reciprocating gear block 6-5 is fixed on the movable cover 1-2, reciprocating teeth are fixed on the left side and the right side of the reciprocating gear block 6-5, and the reciprocating teeth are respectively movably meshed with the corresponding reciprocating half gears 6-4;
the guide block 6-6 is arranged in the reciprocating tooth block 6-5 in a penetrating way, and the upper end of the guide block 6-6 is fixed at the bottom of the support frame 4 by screws;
the driving motor 6-1 drives the driving gear 6-2 on the output end of the front side, the driving gear 6-2 rotates and is respectively meshed with the rotating gears 6-3 on the left side and the right side to synchronously rotate, the rotating gears 6-3 on the two sides respectively drive the rotating shafts to rotate, so that the reciprocating half gear 6-4 rotates, the reciprocating half gear 6-4 respectively rotates and is meshed with the reciprocating teeth on the corresponding reciprocating tooth block 6-5, the reciprocating tooth block 6-5 drives the movable cover 1-2 to vertically reciprocate, the filter frame 11 on the lower side is vertically moved, and the filter frame 11 on the lower side is vertically moved and is reciprocally shaken in the mixing frame 12, so that the extraction solute and the extraction agent in the filter frame 11 are fully mixed.
Preferably, the intensive mixing mechanism 8 further comprises:
the number of the reinforcing frames 8-1 is two, and the reinforcing frames 8-1 are arranged in an L-shaped structure; the two reinforcing frames 8-1 are oppositely arranged at the left and right sides and are fixed at the bottom of the movable cover 1-2 by screws;
the rotating bracket 8-2 is fixed between the left reinforcing frame 8-1 and the right reinforcing frame 8-2 by screws; the connecting strut 7 is screwed and penetrated in the rotating bracket 8-2 through a bearing; a boss 7-1 is integrally formed and fixed at the upper end of the connecting strut 7, and the boss 7-1 is arranged at the upper side of the rotating bracket 8-2 in a contact manner;
the driven gear 8-3 is sleeved and fixed on the connecting strut 7, and the driven gear 8-3 is sleeved and fixed on the connecting strut 7;
the driving gear 8-4 is meshed with the driven gear 8-3, and a fulcrum shaft is arranged in the driving gear 8-4 in a penetrating manner and fixed;
the driving motor 8-5 is fixed at the bottom of the movable cover 1-2 by screws, an output shaft of the driving motor 8-5 is fixedly connected with the support shaft, and the driving motor 8-5 is connected with an external power supply through a lead; the specific use model of the active motor 8-5 is directly purchased, installed and used from the market according to the actual use requirement;
the driving motor 8-5 is started to drive the driving gear 8-4 to rotate, so that the driven gear 8-3 rotates, the connecting strut 7 rotates, the connecting frame 9 on the lower side is driven to rotate the filter frame 11, and the extraction solute rotates in the extractant.
As a preferable scheme, furthermore, a rotating motor 17 is fixed in a groove at the bottom of the connecting frame 9 by screws, and a stirring shaft is fixed on an output shaft at the bottom of the rotating motor 17 and penetrates between the net rack 10 and the filter frame 11; the stirring rods 18 are sequentially fixed on the outer ring wall of the stirring shaft from top to bottom in equal number and in equal round angle distribution by screws, and the stirring rod 18 positioned at the lowest side is smaller than the stirring rod 18 positioned at the upper side; the rotation of the stirring rod 18 by the rotation of the motor 17 stirs the solute to be extracted in the filter holder 11, and the solute to be extracted is sufficiently mixed with the extractant in the extraction holder 16.
As a preferred scheme, furthermore, a filter rack 19 is screwed in the extraction rack 16 through threads, a filter screen is arranged in the filter rack 19, a plurality of clamping racks 20 are fixed on the circumference of the upper side of the filter rack 19 at equal angles by screws, the clamping racks 20 are arranged in an inverted L-shaped structure, and the clamping racks 20 are clamped on the extraction rack 16; the filter frame 19 filters the extraction liquid flowing out of the upper discharge pipe 15.
The working principle of the specific embodiment is as follows: when the device is used, the support frame 4 is driven upwards through the lifting electric push rods 3 on the left side and the right side, the connecting support column 7 drives the filter frame 11 to be away from the mixing frame 12 upwards, the door 1-1 on the front side of the processing kettle body 1 is opened manually, the net rack 10 is unscrewed from the connecting frame 9, an extraction solute is placed in the filter frame 11, and then the net rack 10 and the connecting frame 9 are screwed down manually; meanwhile, an extracting agent is injected into the mixing frame 12 and is heated by a heating lamp 14; the lifting electric push rods 3 on the two sides push downwards at the same time, so that the support frame 4 drives the movable cover 1-2 and the connecting support 7 to move downwards until the movable cover 1-2 is arranged in the processing kettle body 1, and the filter frame 11 is arranged in the mixing frame 12; the filter frame 11 is driven in different modes by the reciprocating driving mechanism 6 and the reinforced mixing mechanism 8 to move in different ways in the mixing frame 12, so that the extraction solute in the filter frame 11 and the extraction agent in the mixing frame 12 are fully mixed, and the extraction liquid finally flows downwards from the discharge pipe 15 to the extraction frame 16; when the driving motor 6-1 drives the driving gear 6-2 on the output end of the front side of the motor to rotate, the driving gear 6-2 is respectively meshed with and drives the rotating gears 6-3 on the left side and the right side to synchronously rotate, the rotating gears 6-3 on the two sides respectively drive the rotating shafts to rotate, so that the reciprocating half gear 6-4 rotates, the reciprocating half gear 6-4 respectively rotates and is meshed with the reciprocating teeth on the corresponding reciprocating tooth block 6-5, so that the reciprocating tooth block 6-5 drives the movable cover 1-2 to vertically reciprocate, the filter frame 11 on the lower side vertically moves, and the filter frame 11 on the lower side vertically moves and is reciprocally shaken in the mixing frame 12, so that the extraction solute in the filter frame 11 is fully mixed with the extraction agent; when the driving motor 8-5 is started, the driving gear 8-4 is driven to rotate, so that the driven gear 8-3 rotates, the connecting strut 7 rotates, the connecting frame 9 on the lower side is driven to rotate the filter frame 11, and the extraction solute rotates in the extractant; at the same time, the rotation of the motor 17 rotates the stirring rod 18, thereby rotationally stirring the extraction solute in the filter holder 11 and sufficiently mixing the extraction solute with the extractant in the extraction holder 16.
After adopting above-mentioned structure, this embodiment beneficial effect does:
1. the reciprocating drive mechanism 6 drives the movable cover 1-2 to make the filter frame 11 at the lower side do up-and-down reciprocating motion in the mixing frame 12, so that the extraction solute is fully contacted with the extraction agent for decomposition;
2. the reinforced mixing mechanism 8 drives the connecting frame 9 to enable the filter frame 11 to rotate in the mixing frame 12, so that the extraction solute can rotate in the extractant, the two can be fully contacted, and the extraction quality is improved;
3. the agitation operation is performed by driving the agitation rod 18 in the extraction solute, so that the contact between the extraction solute and the extractant is more sufficient.
The above description is only for the purpose of illustrating the technical solutions of the present invention and not for the purpose of limiting the same, and other modifications or equivalent substitutions made by those skilled in the art to the technical solutions of the present invention should be covered within the scope of the claims of the present invention without departing from the spirit and scope of the technical solutions of the present invention.
Claims (6)
1. A biopharmaceutical extraction separation device comprises a processing kettle body (1), wherein an opening door (1-1) is arranged on the front side of the processing kettle body (1), and a movable cover (1-2) is arranged on the upper side of the processing kettle body (1);
it is characterized in that it also comprises:
the two supporting blocks (2) are respectively fixed on the left side and the right side of the upper side of the processing kettle body (1);
the two lifting electric push rods (3) are respectively fixed on the corresponding supporting blocks (2), and the lifting electric push rods (3) are connected with an external power supply;
the support frame (4) is arranged in an inverted U-shaped structure, the support frame (4) is arranged on the upper side of the processing kettle body (1), and the pushing end of the lifting electric push rod (3) is connected with the bottom surface of the support frame (4);
the two connecting support blocks (5) are symmetrically fixed at the bottom of the support frame (4) in the front-back direction, and the bottom of each connecting support block (5) is fixed on the movable cover (1-2);
the reciprocating driving mechanism (6), the reciprocating driving mechanism (6) is arranged between the front connecting support block and the rear connecting support block (5);
the connecting support column (7), the connecting support column (7) is arranged at the lower side of the movable cover (1-2), and the connecting support column (7) is arranged in the processing kettle body (1);
the reinforced mixing mechanism (8), the reinforced mixing mechanism (8) is arranged between the connecting strut (7) and the movable cover (1-2);
the connecting frame (9), the said connecting frame (9) is fixed to the bottom of the connecting strut (7);
the net rack (10), the net rack (10) is rotatably arranged inside the connecting rack (9) through threads;
the filter frame (11), the said filter frame (11) is fixed to the bottom of the net rack (10);
the mixing frame (12) is arranged inside the processing kettle body (1), the mixing frame (12) is arranged on the lower side of the connecting frame (9), and the mixing frame (12) is connected with the processing kettle body (1) through connecting pieces on the left side and the right side;
the guide frame (13) is fixed on the inner bottom surface of the mixing frame (12), the guide frame (13) is arranged in an inverted cone structure, and the upper side of the guide frame (13) is connected with the inner annular wall of the mixing frame (12); a heating lamp (14) is arranged on the outer ring wall of the guide frame (13); the heating lamp (14) is connected with an external power supply;
the discharge pipe (15) is arranged at the bottom of the mixing frame (12) in a penetrating way, and an electromagnetic valve is arranged on the discharge pipe (15);
the extraction frame (16), the extraction frame (16) set up in the downside that mixes frame (12), and the left and right sides of extraction frame (16) all is fixed with support piece, support piece and the interior rampart of the processing kettle body (1) are connected.
2. The biopharmaceutical extraction separation device of claim 1, wherein: the reciprocating drive mechanism (6) comprises:
the driving motor (6-1), the said driving motor (6-1) is fixed on connecting the supporting block (5) of the rear side, the driving motor (6-1) is connected with external power;
the driving gear (6-2) is arranged between the front connecting support block and the rear connecting support block (5), and the driving gear (6-2) is fixed on a front output shaft of the driving motor (6-1);
the two rotating gears (6-3) are respectively meshed with the left side and the right side of the driving gear (6-2), and the rotating gears (6-3) are rotatably arranged in the front connecting support block (5) and the rear connecting support block (5) through rotating shafts which are fixedly penetrated in the rotating gears (6-3);
two reciprocating half gears (6-4), wherein the two reciprocating half gears (6-4) are respectively arranged at the front side of the corresponding rotating gear (6-3), and the reciprocating half gears (6-4) are sleeved and fixed on the corresponding rotating shafts; the tooth directions of the left reciprocating half gear (6) and the right reciprocating half gear (4) are the same;
the reciprocating gear block (6-5) is arranged on the front side of the driving gear (6-2), the reciprocating gear block (6-5) is arranged between the left reciprocating half gear (6-4) and the right reciprocating half gear (6-4), the reciprocating gear block (6-5) is fixed on the movable cover (1-2), reciprocating teeth are fixed on the left side and the right side of the reciprocating gear block (6-5), and the reciprocating teeth are respectively movably meshed with the corresponding reciprocating half gears (6-4);
the guide block (6-6) is arranged in the reciprocating tooth block (6-5) in a penetrating way, and the upper end of the guide block (6-6) is fixed at the bottom of the support frame (4);
the driving motor (6-1) drives the driving gear (6-2) on the output end of the front side, the driving gear (6-2) rotates and is respectively meshed with the rotating gears (6-3) on the left side and the right side to drive the rotating gears to synchronously rotate, the rotating gears (6-3) on the two sides respectively drive the rotating shafts to rotate, thereby leading the reciprocating half gear (6-4) to rotate, leading the reciprocating half gear (6-4) to respectively rotate and be meshed with the reciprocating teeth on the corresponding reciprocating moving tooth block (6-5), thereby leading the reciprocating tooth block (6-5) to drive the movable cover (1-2) to reciprocate up and down, further leading the filter frame (11) at the lower side to move up and down, the extraction solute and the extraction agent in the filter frame (11) are fully mixed by reciprocating shaking in the mixing frame (12).
3. The biopharmaceutical extraction separation device of claim 1, wherein: the intensive mixing mechanism (8) comprises:
the number of the reinforcing frames (8-1) is two, and the reinforcing frames (8-1) are arranged in an L-shaped structure; the two reinforcing frames (8-1) are oppositely arranged and fixed at the bottom of the movable cover (1-2) from left to right;
the rotating bracket (8-2), the rotating bracket (8-2) is fixed between the left and right reinforcing frames (8-1); the connecting strut (7) is screwed and penetrated in the rotating bracket (8-2) through a bearing; a boss (7-1) is fixed at the upper end of the connecting strut (7), and the boss (7-1) is arranged on the upper side of the rotating bracket (8-2) in a contact manner;
the driven gear (8-3), the said driven gear (8-3) is set up and fixed on connecting the pillar (7);
the driving gear (8-4), the said driving gear (8-4) is engaged and set up in the right side of the driven gear (8-3), and the fulcrum shaft of wear-out and fixing in the driving gear (8-4);
the driving motor (8-5), the driving motor (8-5) is fixed at the bottom of the movable cover (1-2), an output shaft of the driving motor (8-5) is fixedly connected with the fulcrum shaft, and the driving motor (8-5) is connected with an external power supply;
the driving motor (8-5) is started to drive the driving gear (8-4) to rotate, so that the driven gear (8-3) rotates, the connecting support (7) rotates, the connecting frame (9) on the lower side is driven to rotate the filter frame (11), and the extraction solute rotates in the extracting agent.
4. The biopharmaceutical extraction separation device of claim 1, wherein: a rotating motor (17) is fixed in a groove at the bottom of the connecting frame (9), a stirring shaft is fixed on an output shaft at the bottom of the rotating motor (17), and the stirring shaft is arranged between the net rack (10) and the filter frame (11) in a penetrating way; the stirring rods (18) are sequentially fixed on the outer ring wall of the stirring shaft from top to bottom in equal number and are distributed and fixed at equal round angles, and the stirring rod (18) positioned at the lowest side is smaller than the stirring rod (18) positioned at the upper side; the stirring rod (18) is rotated by rotating the motor (17), so that the extraction solute in the filter frame (11) is stirred in a rotating way, and the extraction solute and the extractant in the extraction frame (16) are fully mixed.
5. The biopharmaceutical extraction separation device of claim 1, wherein: a filter rack (19) is screwed in the extraction rack (16) through threads, a filter screen is arranged in the filter rack (19), a plurality of clamping racks (20) are distributed and fixed at equal angles on the circumference of the upper side of the filter rack (19), the clamping racks (20) are arranged in an inverted L-shaped structure, and the clamping racks (20) are clamped on the extraction rack (16); the filter frame (19) filters the extraction liquid flowing out of the upper discharge pipe (15).
6. The operating principle of a biopharmaceutical extraction separation device as in claim 1, wherein: when the device is used, the support frame (4) is driven upwards through the lifting electric push rods (3) on the left side and the right side, the connecting support column (7) drives the filter frame (11) to be away from the mixing frame (12) upwards, the opening door (1-1) on the front side of the processing kettle body (1) is opened manually, the net rack (10) is unscrewed from the connecting frame (9), an extraction solute is placed in the filter frame (11), and then the net rack (10) and the connecting frame (9) are screwed up manually; meanwhile, an extracting agent is injected into the mixing rack (12), and the extracting agent is heated by a heating lamp (14); the lifting electric push rods (3) on the two sides push downwards at the same time, so that the support frame (4) drives the movable cover (1-2) and the connecting strut (7) to move downwards until the movable cover (1-2) is arranged in the processing kettle body (1), and the filter frame (11) is arranged in the mixing frame (12); the filter frame (11) is driven in different modes by the reciprocating driving mechanism (6) and the reinforced mixing mechanism (8) to move in different ways in the mixing frame (12), so that the extraction solute in the filter frame (11) and the extraction agent in the mixing frame (12) are fully mixed, and the extraction liquid finally flows downwards from the discharge pipe (15) to the extraction frame (16).
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| CN202111413725.XA CN114028838A (en) | 2021-11-25 | 2021-11-25 | Bio-pharmaceuticals extraction separator |
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| CN202111413725.XA CN114028838A (en) | 2021-11-25 | 2021-11-25 | Bio-pharmaceuticals extraction separator |
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| CN117462989A (en) * | 2023-12-28 | 2024-01-30 | 山西铱倍力科技有限公司 | Crystallization equipment is used in chloroiridium acid production |
| CN117723372A (en) * | 2024-02-18 | 2024-03-19 | 科曼德生物科技(北京)有限公司 | Extraction device for detecting traditional Chinese medicine liquid |
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Application publication date: 20220211 |