CN114010955B - In-vivo phototherapy device with compound regulation function - Google Patents
In-vivo phototherapy device with compound regulation function Download PDFInfo
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- CN114010955B CN114010955B CN202111327522.9A CN202111327522A CN114010955B CN 114010955 B CN114010955 B CN 114010955B CN 202111327522 A CN202111327522 A CN 202111327522A CN 114010955 B CN114010955 B CN 114010955B
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N5/0613—Apparatus adapted for a specific treatment
- A61N5/062—Photodynamic therapy, i.e. excitation of an agent
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0626—Monitoring, verifying, controlling systems and methods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0632—Constructional aspects of the apparatus
- A61N2005/0633—Arrangements for lifting or hinging the frame which supports the light sources
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
- A61N2005/0651—Diodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/065—Light sources therefor
- A61N2005/0651—Diodes
- A61N2005/0653—Organic light emitting diodes
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N5/00—Radiation therapy
- A61N5/06—Radiation therapy using light
- A61N2005/0658—Radiation therapy using light characterised by the wavelength of light used
- A61N2005/0662—Visible light
Abstract
The application discloses an in vivo phototherapy device with compound regulatory function, include: a chassis; a bracket slidably mounted on the chassis in a first direction; a light source slidably mounted on the support in a second direction for providing therapeutic radiation; the first driving mechanism is arranged on the underframe and used for driving the bracket to slide back and forth along the first direction; the second driving mechanism is arranged on the bracket and used for driving the light source to slide back and forth along the second direction. The light source is arranged on the bracket, and the therapeutic area with a corresponding shape is formed by controlling the movement rates of the bracket and the light source; the driving mechanism is used for controlling the light source and/or the bracket to move, and the shape and the size of the radiation area of the light source are adjusted through the speed adjustment of the movement of the light source and/or the bracket, so that the shape and the size of different affected areas are met, and the radiation of non-affected areas can be avoided.
Description
Technical Field
The present disclosure relates generally to the technical field of photomedical equipment, and in particular, to an in-vivo phototherapy device with a compound regulation function.
Background
Phototherapy includes photodynamic therapy (PDT) which is the targeting of light having a specific wavelength or wavelength band to target cells, which are sensitized by administration of a photoreactive, photoinitiating or photosensitizing agent. Photoreactive agents have a specific light absorption band and are typically administered to a patient by intravenous injection, oral administration, or by local delivery to a treatment site. Often abnormal cells within the body can selectively absorb specific photoreactive agents far in excess of normal amounts for healthy cells. When the abnormal cells have absorbed the photoreactive agent and/or are linked together with their molecules, the abnormal cells may be treated by exposing the cells to light having an appropriate wavelength or wavelength band, and the appropriate wavelength or wavelength band generally corresponds to the absorption wavelength or wavelength band of the photoreactive agent.
The goal of PDT is to make a diagnosis or treatment. In diagnostic applications, the wavelength of light is selected to fluoresce the photoreactive agent as a means to obtain information related to the target cell without damaging the target cell. In therapeutic applications, the wavelength of light delivered to the target cells being treated with the photoreactive agent causes photoreaction of the photoreactive agent with oxygen in the local target cells, thereby producing free radical species (e.g., singlet oxygen) that lyse or necrose the local cells.
When the diseases are in human body, such as bladder cancer, throat cancer, bronchus cancer and the like, the conventional medicine taking means take effect slowly, so that the photomedical mode is mostly adopted. At present, the light source for in-vivo treatment is mainly a laser optical fiber, however, in actual use, the patient has the characteristics of uneven appearance and non-uniform overall shape, so that the optical fiber is difficult to emit light with uniform energy and is suitable for the shape of the affected part, the light energy loss of the optical fiber is larger, the light emitting area is smaller, and the control is not easy. Therefore, we propose an in vivo phototherapy device with a compound adjusting function, which is used for solving the problems of large light energy loss, poor luminous consistency, small luminous area and difficult control.
Disclosure of Invention
In view of the above-described drawbacks or shortcomings of the prior art, it is desirable to provide an in-vivo phototherapy device with a complex adjustment function that improves the uniformity of light emission, enlarges the area of the illuminated area of the light source, and is simple in structure and easy to implement.
In a first aspect, the present application provides an in vivo phototherapy device with complex regulatory functions, comprising:
a chassis;
a bracket slidably mounted on the chassis in a first direction;
a light source slidably mounted on the support in a second direction for providing therapeutic radiation;
the first driving mechanism is arranged on the underframe and used for driving the bracket to slide back and forth along the first direction;
the second driving mechanism is arranged on the bracket and used for driving the light source to slide back and forth along the second direction.
According to the technical scheme provided by the embodiment of the application, at least one section of bracket movement area is arranged on the underframe; the support is provided with light source movement areas with different lengths and/or positions corresponding to each section of support movement area; the movement rate u of the light source in the light source movement area meets the following conditions:
u is more than or equal to 5L (meters per second);
wherein L is the length of the light source movement area.
According to the technical scheme provided by the embodiment of the application, when the working current of the light source is constant, the movement speed u of the light source meets the following conditions:
u＝(u lower part(s) *L Lower part(s) )/L；
Wherein L is Lower part(s) The length of the light source movement area with the shortest length; u (u) Lower part(s) The movement speed of the light source is the shortest light source movement area.
According to the technical scheme provided by the embodiment of the application, when the movement rate of the light source is constant, the working current I of the light source meets the following conditions:
I＝(I lower part(s) *L Lower part(s) )/L；
Wherein L is Lower part(s) The length of the light source movement area with the shortest length; i Lower part(s) The operating current is set for the shortest length light source.
According to the technical scheme provided by the embodiment of the application, the third driving mechanism for driving the bracket to rotate is further arranged on the underframe.
According to the technical scheme provided by the embodiment of the application, the method further comprises the following steps: and the identification module is fixed on the bracket and is used for acquiring the shape, the image and the size of the treatment area.
According to the technical scheme provided by the embodiment of the application, the identification module is a miniature camera fixed on the bracket.
According to the technical scheme provided by the embodiment of the application, the light source is an OLED light source, an LED light source, a miniLED light source, a microroll light source, a quantum dot light source or a perovskite LED.
In summary, the technical scheme discloses a specific structure of an in-vivo phototherapy device with a compound adjusting function. The light source is arranged on the bracket, and the therapeutic area with a corresponding shape is formed by controlling the movement rates of the bracket and the light source; the driving mechanism is used for controlling the light source and/or the bracket to move, and the shape and the size of the radiation area of the light source are adjusted through the speed adjustment of the movement of the light source and/or the bracket, so that the shape and the size of different affected areas are met, and the radiation of non-affected areas can be avoided; further, the movement speed of the light source is inversely proportional to the length of the passing bracket, or the brightness of the screen is inversely proportional to the length of the passing bracket, so that the formed phototherapy area has equal radiation energy at all positions.
Drawings
Other features, objects and advantages of the present application will become more apparent upon reading of the detailed description of non-limiting embodiments, made with reference to the following drawings, in which:
fig. 1a is a schematic diagram of an in vivo phototherapy device with a compound adjustment function using a single light source.
Fig. 1b is a schematic structural diagram of an in-vivo phototherapy device with a compound adjustment function when a plurality of light sources are spliced.
Fig. 2 is a schematic structural diagram of the treatment region formed in example 1.
Fig. 3a is a schematic diagram of the treatment area formed in example 2.
Fig. 3b is a schematic diagram of the treatment area formed in example 2.
Fig. 3c is a schematic diagram of the treatment area formed in example 2.
Fig. 4 is a schematic structural diagram of the treatment region formed in example 3.
Fig. 5 is a schematic view of the treatment area formed in example 4.
Fig. 6 is a schematic structural diagram of the treatment region formed in example 1.
Fig. 7 is a schematic process diagram of the treatment area formed in fig. 2.
Fig. 8 is a schematic process diagram of the treatment area formed in fig. 3 a.
Fig. 9 is a schematic process diagram of the treatment area formed in fig. 3 b.
Fig. 10 is a schematic process diagram of the treatment area formed in fig. 3 c.
Fig. 11 is a schematic process diagram of the treatment area formed in fig. 4.
Fig. 12 is a schematic process diagram of the treatment area formed in fig. 5.
Reference numerals in the drawings: 1. a bracket; 2. a light source; 3. a chassis; 4 phototherapy area.
Detailed Description
The present application is described in further detail below with reference to the drawings and examples. It is to be understood that the specific embodiments described herein are merely illustrative of the invention and are not limiting of the invention. It should be noted that, for convenience of description, only the portions related to the invention are shown in the drawings.
It should be noted that, in the case of no conflict, the embodiments and features in the embodiments may be combined with each other. The present application will be described in detail below with reference to the accompanying drawings in conjunction with embodiments.
Example 1
Referring to fig. 1a and 1b, a schematic structural diagram of an in-vivo phototherapy device with a compound adjustment function provided in the present application includes:
the underframe 3 is made of a steel plate with a sliding groove;
a bracket 1 slidably mounted on the chassis 3 in a first direction; the bottom of the bracket 1 is fixedly provided with a sliding block, and the sliding block can slide in a sliding groove of the underframe 3 to drive the bracket 1 to move along a path provided by the sliding groove;
here, the first direction is a sliding path direction provided by the chute; the bracket 1 is provided with a chute which is arranged along the length direction of the bracket 1;
a light source 2 slidably mounted on the support 1 in a second direction for providing therapeutic radiation; the light source is fixed on a sliding block, and the sliding block can slide in a sliding groove of the bracket 1 to drive the light source 2 to move along the length direction of the bracket 1;
here, as shown in fig. 1a, the light source 2 may be a single OLED light source; in other embodiments, as shown in FIG. 1b, the light source may also be a plurality of OLED light sources that are tiled together. Whether one or more light sources, a reciprocating motion can be achieved on the holder as long as the length of the distribution area is smaller than the length of the holder 1.
In other embodiments, the light source 2 may also be an LED light source, a miniLED light source, a microLED light source, a quantum dot light source, or a perovskite LED.
The light source can be selected according to the treatment requirement, and the phototherapy effect of the light with different colors is achieved:
the light irradiation depth of yellow green light with the wave band of 510 nm-590 nm is between blue light and red light, so that the dredging and the expansion of capillary vessels with the skin depth can be promoted, the resistance of cells can be enhanced, and the treatment effect of an affected part can be accelerated.
Red light with the wave band of 590-810 nm can lead mitochondria to release cytochrome c oxidase, increase adenosine triphosphate, and the cells provide energy by using the adenosine triphosphate, thereby promoting the metabolism of the cells; meanwhile, the red light irradiation heats molecules in blood vessels, regulates the vasodilation and improves the blood circulation; blue light irradiation in the 440-510 nm band can be used for relieving pain and swelling caused by inflammation.
A first driving mechanism provided on the chassis 3 for driving the carriage 1 to slide back and forth in a first direction;
specifically, the first driving mechanism is a micro servo motor, which is fixed at one end of the chassis 3; a lead screw is axially fixed on the output shaft of the miniature servo motor, and a slide block of the bracket 1 is in threaded connection with the lead screw; the length direction of the screw rod is parallel to the sliding direction of the sliding block of the bracket 1; the miniature servo motor drives the bracket 1 on the sliding block to reciprocate by driving the screw rod to rotate.
In other embodiments, the transmission between the first driving mechanism and the bracket 1 may also be other driving modes of reciprocating motion, for example, a cylinder structure is selected: the driving cylinder is arranged on the underframe 3, a piston rod of the driving cylinder is connected with a sliding block at the bottom of the bracket 1, and the driving cylinder is started to drive the bracket to reciprocate along the length direction of a sliding groove on the underframe 3.
The second driving mechanism is arranged on the bracket 1 and is used for driving the light source 2 to slide back and forth along the second direction;
specifically, the second driving mechanism is a micro servo motor, which is fixed at one end of the bracket 1; a lead screw is axially fixed on the output shaft of the miniature servo motor, and a slide block for mounting the light source 2 is in threaded connection with the lead screw; the length direction of the screw rod is parallel to the sliding direction of the sliding block of the light source 2; the miniature servo motor drives the light source 2 on the slide block to reciprocate by driving the screw rod to rotate.
In other embodiments, the transmission between the second driving mechanism and the light source 2 may also be other driving modes of reciprocating motion, for example, a cylinder structure is selected: the driving cylinder is arranged on the bracket 1, a piston rod of the driving cylinder is connected with a sliding block provided with the light source 2, and the driving cylinder is started to drive the light source 2 to reciprocate along the length direction of the bracket 1.
In the process that the micro servo motor drives the corresponding bracket 1 or the light source 2 to reciprocate, an illumination area equivalent to the reciprocating path length of the micro servo motor can be formed, when the light source 2 is a single point light source, the punctiform accurate phototherapy area can be realized through the driving mode of the embodiment, and the regional phototherapy area with adjustable shape and size can be formed.
The identification module is fixed on the bracket 1 and is used for acquiring the shape, the image and the size of the treatment area; the type of the identification module can be a miniature camera, so that the device is beneficial to acquiring an internal image in real time in the process of extending into the device, and the insertion position is accurately controlled, so that accurate treatment is realized.
Wherein, one end of the underframe 3 is fixed with a flexible supporting rod for sending the bracket, the miniature servo motor, the lead screw, the sliding block and the phototherapy device integrated with the light source into the body or taking the phototherapy device out of the body. Meanwhile, a control module for controlling the micro servo motor and the light source is connected with the micro servo motor through a control circuit, and the control circuit is arranged along with the flexible supporting rod, so that power supply and control of the micro servo motor and the light source are realized. In addition, the control module is also connected with the identification module on the bracket 1 through a line, and the movement of the bracket and/or the light source is controlled by acquiring focus information of the identification module.
Further, the underframe 3 is provided with at least one section of bracket moving area, and the bracket 1 is provided with light source moving areas with different lengths and/or positions corresponding to each section of bracket moving area;
the movement rate u of the light source 2 in the light source movement region satisfies the following condition:
u is more than or equal to 5L (meters per second);
wherein L is the length of the light source movement area, and the unit of L is meter. For example, where L is 0.01 meters, u.gtoreq.0.05 meters/second; the above definition of the movement rate of the light source 2 allows the light source 2 to cover the area of the phototherapy area corresponding to the entire stent 1 during the movement of the stent 1, thereby forming an area-shaped treatment area.
Among them, it is preferable that the present embodiment makes the irradiation amounts of the light sources 2 corresponding to the respective phototherapy areas in movement equal by:
mode one:
it is assumed that the distance of the light source from the treated area is equal during the movement of the light source 2 and the support 1, and that the movement rate u of the light source 2 satisfies the following condition when the operating current of the light source 2 is constant:
u＝(u lower part(s) *L Lower part(s) )/L；
Wherein L is Lower part(s) The length of the light source movement area with the shortest length; u (u) Lower part(s) The rate of movement of the light source 2 is the shortest length of the light source movement zone.
For example, the number of the cells to be processed,
the support movement area is a section, and the light source movement area is one; the total length of the rack 1 is l=0.01 meters; the length of the light source movement area is 0.01 meter, and the corresponding light source movement speed u is more than or equal to 0.05 meter/second;
setting u Lower part(s) ＝0.4，L Lower part(s) =0.004; the light source movement rate is u=0.16 m/s;
because the irradiation amount of the phototherapy region is inversely proportional to the distance between the light source and the phototherapy region, is directly proportional to the illumination intensity of the light source, is directly proportional to the illumination time length, and is directly proportional to the working current of the light source; within the same movement distance, the illumination duration is proportional to the movement rate. Therefore, in this embodiment, the distance between the light source and the region to be treated is equal during the movement of the light source and the stent, and it is assumed that the movement rate of the light source is inversely proportional to the movement range of the light source when the operating current of the light source 2 is constant, so that the irradiation amounts of the light source to the phototherapy region in different stent movement regions are equal.
Mode two
Assuming that the distance of the light source from the treated area is equal during the movement of the light source 2 and the support 1, the operating current I of the light source 2 satisfies the following condition when the movement rate of the light source 2 is constant:
I＝(I lower part(s) *L Lower part(s) )/L；
Wherein L is Lower part(s) The length of the light source movement area with the shortest length; i Lower part(s) The operating current is set for the shortest length light source.
For example:
the support moving area is a section, and one corresponding light source moving area is arranged; the total length of the rack 1 is l=0.01 meters;
setting I Lower part(s) ＝4，L Lower part(s) =0.004; the light source operating current is i=1.6 amps;
because the irradiation amount of the phototherapy region is inversely proportional to the distance between the light source and the phototherapy region, is directly proportional to the illumination intensity of the light source, is directly proportional to the illumination time length, and is directly proportional to the working current of the light source; within the same movement distance, the illumination duration is proportional to the movement rate. Therefore, in this embodiment, the distance between the light source and the region to be treated is equal during the movement of the light source and the support, and it is assumed that when the movement rate of the light source 2 is constant, the working current of the light source is inversely proportional to the movement range of the light source, so that the irradiation amounts of the light source to the phototherapy region in different support movement regions are equal.
The corresponding phototherapy region is formed by controlling the movement rates of the support 1 and the light source 2, and the movement rate of the light source is inversely proportional to the length of the support passing through, or the brightness of the screen is inversely proportional to the length of the support passing through, so that the equal radiation energy of each position of the formed phototherapy region is ensured.
Further, the bracket movement area is a section; one corresponding light source movement area is provided; the total length of the bracket 1 is L=0.01m, the length of the light source movement area is 0.01m, the light source movement speed u is equal to or greater than 0.05 m/s;
setting u Lower part(s) ＝0.4，L Lower part(s) ＝0.004；
The light source movement rate is u=0.16 m/s;
setting I Lower part(s) ＝4，L Lower part(s) ＝0.004；
The light source operating current is i=1.6 amps;
as shown in fig. 2, a phototherapy region 4 of a rectangular shape may be formed; fig. 7 is a schematic diagram of a process of forming a treatment area, in which a light source movement area is provided, a bracket moves from left to right along the direction of an arrow, the movement area of the light source is a shadow part in the drawing, and the rectangular phototherapy area shown in fig. 2 can be formed through the movement process of fig. 7.
Example 2
In the embodiment, on the basis of embodiment 1, the movement area of the bracket is three sections; the three light source movement areas are respectively a first light source movement area, a second light source movement area and a third light source movement area; the total length of the bracket 1 is l=0.01m, the length of the light source movement area is 0.008m in the first light source movement area, the length of the light source movement area is 0.004m in the second light source movement area, and the length of the light source movement area is 0.008m in the third light source movement area; the light source movement speed u is more than or equal to 0.04 m/s in the first light source movement area and the third light source movement area; in the second light source movement area, the light source movement speed u is more than or equal to 0.02 m/s;
setting u Lower part(s) ＝0.4，L Lower part(s) ＝0.004；
Then in the first light source movement region and the third light source movement region, the light source movement rate u=0.0016/0.008=0.2 meters/second;
then in the second light source movement zone, the light source movement rate u=0.0016/0.004=0.4 m/s;
here, the length L of the light source movement region having the shortest length is first determined Lower part(s) Determining the light source movement speed u of the light source movement area with the shortest length Lower part(s) ；
Setting I Lower part(s) ＝4，L Lower part(s) ＝0.004；
The working current of the light source in the first light source movement area and the third light source movement area is I=0.016/0.008=2 amperes;
then in the second light source movement region, the light source operating current is i=0.016/0.004=4 amps;
the phototherapy region 4 shown in fig. 3a may be formed in a shape protruding upward at a middle position; FIG. 8 is a schematic illustration of the process of forming a treatment area with the stent moving from left to right in the direction of the arrows and the light source moving in the shaded area of the figure;
the phototherapy region 4 shown in fig. 3b may be formed in a shape of a central downward depression; FIG. 9 is a schematic illustration of the process of forming a treatment area with the stent moving from left to right in the direction of the arrows and the light source moving in the shaded area of the figure;
the phototherapy region 4 shown in fig. 3c may be formed in a shape of a central depression at a central position;
the specific forming process of the phototherapy area formed in fig. 3c is shown in fig. 10, in which the process of moving the light source of the first light source moving area, the second light source moving area and the third light source moving area and the support are sequentially from left to right in the drawing, the support moves from left to right along the arrow direction, the moving area of the light source is a shadow part in the drawing, and the phototherapy area formed in fig. 3c can be obtained through the moving process in fig. 10.
Example 3
In the embodiment, on the basis of embodiment 1, the movement area of the bracket is two sections; the two light source movement areas are respectively a first light source movement area and a second light source movement area; the total length of the bracket 1 is l=0.01m, the length of the light source movement area is 0.01m in the first light source movement area, and the length of the light source movement area is 0.006m in the second light source movement area; in the first light source movement area, the light source movement speed u is more than or equal to 0.05 m/s; in the second light source movement area, the light source movement speed u is more than or equal to 0.03 m/s;
setting u Lower part(s) ＝0.4，L Lower part(s) ＝0.004；
Then in the first light source movement zone, the light source movement rate u=0.0016/0.01=0.16 m/s;
then in the second light source movement zone, the light source movement rate u=0.0016/0.006=0.267 m/s;
setting I Lower part(s) ＝4，L Lower part(s) ＝0.004；
Then in the first light source movement region, the light source operating current is i=0.016/0.01=1.6 amps;
then in the second light source movement region, the light source operating current is i=0.016/0.006=2.67 amps;
the phototherapy region 4 shown in fig. 4 may be formed in an L-shape; fig. 11 is a schematic diagram of the process of forming a treatment area, in which the stent is moved from left to right in the direction of the arrow and the light source is moved in the hatched area.
Example 4
In the embodiment, on the basis of embodiment 1, the movement area of the bracket is five sections; the three light source movement areas are respectively a first light source movement area, a second light source movement area, a third light source movement area, a fourth light source movement area and a fifth light source movement area; the total length of the bracket 1 is L=0.01m, the length of the light source moving area is 0.01m in the first light source moving area, the third light source moving area and the fifth light source moving area, and the length of the light source moving area is 0.008m in the second light source moving area and the fourth light source moving area; the light source movement speed u is more than or equal to 0.05 m/s in the first light source movement area, the third light source movement area and the fifth light source movement area; the light source movement speed u is more than or equal to 0.04 m/s in the second light source movement area and the fourth light source movement area;
setting u Lower part(s) ＝0.4，L Lower part(s) ＝0.004；
Then in the first, third and fifth light source movement zones, the light source movement rate u=0.0016/0.01=0.16 meters/second;
then in the second light source movement region and the fourth light source movement region, the light source movement rate u=0.0016/0.008=0.2 m/s;
setting I Lower part(s) ＝4，L Lower part(s) ＝0.004；
The light source working current is i=0.016/0.01=1.6 amps in the first, third and fifth light source movement zones;
then in the second light source movement area and the fourth light source movement area, the working current of the light source is I=0.016/0.008=2 amperes;
the phototherapy area 4 shown in fig. 5 can be formed, and the phototherapy areas of the second light source movement area and the fourth light source movement area are concave towards the center; fig. 12 is a schematic diagram of the process of forming a treatment area, in which the stent is moved from left to right in the direction of the arrow and the light source is moved in the shaded area.
Example 5
In the embodiment, on the basis of the embodiment 1, a third driving mechanism is designed on the underframe 3 and is used for driving the bracket 1 to rotate; at this time, the reciprocating motion of the light source 2 on the support 1 is matched with the rotation and the movement of the support, so that a three-dimensional treatment area can be formed.
The third driving mechanism can be a rotating shaft and a micro servo motor which are matched for use, the rotating shaft is arranged at one end of the bracket 1, the micro servo motor is positioned on the underframe 3, the rotating shaft of the bracket 1 is coaxially fixed on the rotating shaft of the micro servo motor, and the micro servo motor can drive the bracket to rotate around the end part of the bracket when working;
at this time, as shown in fig. 6, a three-dimensional stereoscopic pattern having a certain thickness may be formed.
Example 6
In this embodiment, based on embodiment 1, the control module classifies the severity of the focal zone, for example, a long focal zone, in which the severity is a, and the severity is B at both ends, by using the image identified by the identification module fixed on the bracket 1, wherein the severity of a is greater than B; the control module adjusts and controls the rotating speed of the micro servo motor to be a when judging that the position of the sliding block is aligned with the middle part of the focus, and adjusts and controls the rotating speed of the micro servo motor to be b when judging that the position of the sliding block is aligned with the two ends of the focus, wherein a is smaller than b. The moving speed of the treatment light source is adjusted according to the severity of the focus area, the area with heavier severity can be treated for a longer time in one treatment period, the treatment scheme is customized according to the local conditions, and the treatment effect is improved.
The foregoing description is only of the preferred embodiments of the present application and is presented as a description of the principles of the technology being utilized. It will be appreciated by persons skilled in the art that the scope of the invention referred to in this application is not limited to the specific combinations of features described above, but it is intended to cover other embodiments in which any combination of features described above or equivalents thereof is possible without departing from the spirit of the invention. Such as the above-described features and technical features having similar functions (but not limited to) disclosed in the present application are replaced with each other.
Claims (8)
1. An in vivo phototherapy device with compound regulatory functions, comprising:
a chassis (3);
a bracket (1) slidably mounted on the chassis (3) in a first direction;
a light source (2) slidably mounted on the support (1) in a second direction for providing therapeutic radiation;
the first driving mechanism is arranged on the underframe (3) and used for driving the bracket (1) to slide back and forth along the first direction;
the second driving mechanism is arranged on the bracket (1) and used for driving the light source (2) to slide back and forth along the second direction;
the corresponding phototherapy region is formed by controlling the movement rate of the support (1) and the light source (2), and the movement rate of the light source (2) is inversely proportional to the length of the support (1) passing through, or the brightness of the screen body is inversely proportional to the length of the support (1) passing through, so that the equal radiation energy of each position of the formed phototherapy region is ensured.
2. An in vivo phototherapy device with compound regulation function according to claim 1, characterized in that at least one section of support movement area is arranged on the underframe (3); the support (1) is provided with light source movement areas with different lengths and/or positions corresponding to each section of support movement area; the movement rate u of the light source (2) in the light source movement area meets the following conditions:
u is more than or equal to 5L (meters per second);
wherein L is the length of the light source movement area.
3. An in vivo phototherapy device with complex regulatory functions according to claim 2, characterized in that the rate of movement u of the light source (2) satisfies the following condition when the operating current of the light source (2) is constant:
u＝(u lower part(s) *L Lower part(s) )/L；
Wherein L is Lower part(s) The length of the light source movement area with the shortest length; u (u) Lower part(s) The rate of movement of the light source (2) being the shortest length of the light source movement zone.
4. An in vivo phototherapy device with complex regulatory functions according to claim 3, characterized in that the operating current I of the light source (2) fulfils the following condition when the rate of movement of the light source (2) is constant:
I＝(I lower part(s) *L Lower part(s) )/L；
Wherein L is Lower part(s) The length of the light source movement area with the shortest length; i Lower part(s) The operating current is set for the shortest length light source.
5. An in vivo phototherapy device with compound regulation function according to any of claims 1-4, characterized in that the chassis (3) is further provided with a third driving mechanism for driving the bracket (1) to rotate.
6. An in vivo phototherapy device with compound regulatory functions according to any one of claims 1-4, further comprising: and the identification module is fixed on the bracket (1) and is used for acquiring the shape, the image and the size of the treatment area.
7. An in vivo phototherapy device with complex regulatory functions according to claim 6, characterized in that said identification module is a miniature camera fixed on said support (1).
8. An in vivo phototherapy device with compound regulation function according to any of claims 1-4, characterized in that the light source (2) is an OLED light source, an LED light source, a miniLED light source, a microled light source, a quantum dot light source or a perovskite LED.
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