CN114010754A - Traditional Chinese medicine formula for treating recurrent oral ulcer - Google Patents

Traditional Chinese medicine formula for treating recurrent oral ulcer Download PDF

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CN114010754A
CN114010754A CN202111614085.9A CN202111614085A CN114010754A CN 114010754 A CN114010754 A CN 114010754A CN 202111614085 A CN202111614085 A CN 202111614085A CN 114010754 A CN114010754 A CN 114010754A
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traditional chinese
chinese medicine
oral ulcer
recurrent oral
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何彦生
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/34—Campanulaceae (Bellflower family)
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
    • A—HUMAN NECESSITIES
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    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
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    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
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    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
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    • A61P1/02—Stomatological preparations, e.g. drugs for caries, aphtae, periodontitis

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Abstract

The invention provides a traditional Chinese medicine formula for treating recurrent oral ulcer, which is prepared from the following raw materials in parts by mass: 9g of cape jasmine, 20g of lophatherum gracile, 15g of radix bupleuri, 20g of astragalus membranaceus, 15g of cimicifuga foetida, 12g of bighead atractylodes rhizome, 12g of dried ginger, 15g of codonopsis pilosula, 15g of fructus amomi, 20g of prepared rehmannia root, 12g of golden cypress, 12g of rhizoma anemarrhenae, 12g of moutan bark, 15g of rhizoma alismatis, 12g of dandelion and 12g of liquorice; the traditional Chinese medicine is prepared from natural traditional Chinese medicine raw materials, is safe, has no toxic or side effect, is warm and clear in combination, can be used for both reinforcing and reducing diarrhea, has the effect of regulating three jiao, treats both heart, spleen, liver and kidney, has an effective treatment effect on recurrent oral ulcer, can greatly shorten the rehabilitation time, can improve the immunity of the organism, and reduces the recurrence.

Description

Traditional Chinese medicine formula for treating recurrent oral ulcer
Technical Field
The invention relates to the field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine formula for treating recurrent oral ulcer.
Background
Recurrent oral ulcer is a common disease in clinic, is also a typical oral mucosa frequently-occurring disease, can present a circular ulcer or an isolated oval ulcer at any position of the oral mucosa of a patient, can generate severe pain after the disease occurs, is easy to recur, and has serious negative effects on the life quality and the life quality of the patient. At present, in western medicine, the disease has no specific medicine, is mostly treated according to symptoms, can only relieve the pain of a patient, prevent secondary infection and promote the healing of an ulcer area, only treats the symptoms but not the root cause, and has serious relapse; according to a large number of clinical practice observations, patients with recurrent oral ulcer are considered to be obese, have more phlegm-dampness, damp-heat or yang-deficiency constitution, are engaged in nervous brainworkers mostly, or are much like to eat cold drinks and the like; the disease location is mainly in the spleen, and further develops into damp-heat turbid toxin accumulation on the basis of spleen yang deficiency; the deficiency of spleen yang in the middle energizer leads to the disharmony of the upper and lower energizers with water and heart-kidney disharmony, the upper energizer often manifests deficiency-heat and the upper energizer often manifests flaming-up by latent fire, clinically manifested as intermingled deficiency and excess, mixed cold and heat, lingering illness, and even regular relapse every month.
Disclosure of Invention
Aiming at the technical defects, the invention aims to provide a traditional Chinese medicine formula for treating recurrent oral ulcer, which is prepared from traditional Chinese medicines and solves the problems that no effective treatment agent exists in the recurrent oral ulcer at present and the recurrence is serious.
In order to solve the technical problems, the invention adopts the following technical scheme:
a traditional Chinese medicine formula for treating recurrent oral ulcer is prepared from the following raw materials in parts by mass: 9g of cape jasmine, 20g of lophatherum gracile, 15g of radix bupleuri, 20g of astragalus membranaceus, 15g of cimicifuga foetida, 12g of bighead atractylodes rhizome, 12g of dried ginger, 15g of codonopsis pilosula, 15g of fructus amomi, 20g of prepared rehmannia root, 12g of golden cypress, 12g of rhizoma anemarrhenae, 12g of moutan bark, 15g of rhizoma alismatis, 12g of dandelion and 12g of liquorice.
The invention has the beneficial effects that: the traditional Chinese medicine is prepared from natural traditional Chinese medicine raw materials, is safe, has no toxic or side effect, is warm and clear, can be used for both reinforcing and reducing the diarrhea, has the functions of regulating the three heats and treating the heart, spleen, liver and kidney simultaneously, has an effective treatment effect on recurrent oral ulcer, can greatly shorten the rehabilitation time, can improve the immunity of the organism and reduce the recurrence.
The following is combined with the main components in the invention to further explain the beneficial effects:
gardenia: has the effects of relieving restlessness, clearing heat, promoting diuresis, cooling blood and removing toxic substances; has repercussive and analgesic effects.
Herba lophatheri: sweet and light in nature and taste, can clear heart fire, induce diuresis and eliminate dysphoria, and has good curative effects on swelling and aching of gum, stomatitis and the like.
Bupleurum root: has the efficacies of harmonizing exterior and interior, soothing liver and invigorating yang.
Astragalus root: has effects in consolidating exterior, expelling toxin, expelling pus, promoting urination, and promoting granulation.
Cimicifugae foetidae: has the effects of relieving exterior syndrome, promoting eruption, clearing away heat and toxic materials, and invigorating yang.
White atractylodes rhizome: has effects in invigorating spleen and stomach, eliminating dampness, promoting diuresis, stopping sweating, and preventing miscarriage.
Dried ginger: has the effects of warming middle-jiao, expelling cold, restoring yang and dredging collaterals.
Codonopsis pilosula: has the effects of invigorating spleen and replenishing qi, regulating stomach function, promoting fluid production, eliminating phlegm and relieving cough.
Amomum fruit: has effects in promoting qi circulation, regulating middle warmer, regulating stomach function, and activating spleen; it is effective in treating abdominal pain, abdominal distention, anorexia, dysphagia, emesis, cold diarrhea, dysentery, and fetal movement during pregnancy.
Prepared rehmannia root: has effects in replenishing blood, nourishing yin, replenishing essence, and replenishing marrow.
Phellodendron bark: has the effects of clearing heat, eliminating dampness, purging fire, removing toxic substances, removing bone-steaming, and clearing away deficiency heat.
Rhizoma anemarrhenae: has effects of clearing heat-fire, nourishing yin and moistening dryness.
Moutan bark: has effects of clearing heat, cooling blood, promoting blood circulation and removing blood stasis.
Rhizoma alismatis: has effects of promoting diuresis, eliminating dampness, clearing heat, eliminating turbid pathogen, and reducing blood lipid.
Dandelion: has the effects of clearing away heat and toxic materials, promoting urination, and resolving hard mass.
Licorice root: has the effects of resisting inflammation and virus, tonifying qi and strengthening the middle warmer, relieving spasm and pain, moistening lung for arresting cough, purging pathogenic fire for removing toxic substances, harmonizing the medicines, protecting liver for removing toxic substances and enhancing immunity.
The following is further explained by combining the characteristics of the beneficial effects of the compatibility of the medicines of the invention:
the gardenia, the rhizoma cimicifugae and the lophatherum gracile leaf are matched with the radix bupleuri to gently clear the heat in the upper jiao; the combination of radix bupleuri and cimicifugae foetidae has the function of 'fire stagnation', and the pathogenic fire toxin is dispersed from the exterior because the property of the drug is thin and ascends, so the drug is suitable for both excess fire and deficient fire in the upper jiao; the astragalus root and the cimicifuga foetida have the effects of tonifying qi and expelling toxin.
Radix astragali, radix codonopsitis, rhizoma zingiberis, rhizoma atractylodis macrocephalae and fructus amomi have the effects of tonifying qi, invigorating spleen, warming middle-jiao, eliminating dampness and dispelling cold, tonifying middle-jiao, deficiency-cold and improving the immunity of the organism, and are clinically applied to a 'soil-supplementing fire-nourishing method' by matching the radix glycyrrhizae and the fructus amomi; bupleurum root, radix bupleuri, in combination with Sha ren, is also used clinically in the methods of smoothing wood and consolidating earth.
Cortex moutan has effects of promoting blood circulation, cooling blood, dispelling blood stasis, and inhibiting bacteria, and cortex Phellodendri, radix rehmanniae Preparata, cortex moutan, Alismatis rhizoma, and rhizoma anemarrhenae are combined into pill for nourishing yin, clearing heat, cooling blood serum lower energizer (liver and kidney) deficiency fire, and guiding fire to origin; dandelion, liquorice, alisma orientale, gardenia and phellodendron are combined to detoxify and drain turbidity.
The formula is warm and clear and has the functions of tonifying and purging, the three jiao is regulated at the same time, and the heart, spleen, liver and kidney are treated at the same time; the traditional Chinese medicine mainly has the effects of warming middle-jiao, tonifying spleen, resolving turbidity, detoxifying and discharging turbidity, treats recurrent oral ulcer by using the triple energizer, and can shorten the rehabilitation time and reduce the recurrence frequency.
Detailed Description
The present invention will be described in further detail with reference to examples, but the present invention is not limited thereto.
A traditional Chinese medicine formula for treating recurrent oral ulcer is prepared from the following raw materials in parts by mass: 9g of cape jasmine, 20g of lophatherum gracile, 15g of radix bupleuri, 20g of astragalus membranaceus, 15g of cimicifuga foetida, 12g of bighead atractylodes rhizome, 12g of dried ginger, 15g of codonopsis pilosula, 15g of fructus amomi, 20g of prepared rehmannia root, 12g of golden cypress, 12g of rhizoma anemarrhenae, 12g of moutan bark, 15g of rhizoma alismatis, 12g of dandelion and 12g of liquorice;
the raw materials with the formula amount are decocted with 900ml of water to prepare oral liquid, 3 times a day, and 300ml of the oral liquid is taken orally each time.
Or making into powder, pill or capsule at a certain proportion, and taking 3 times daily, 15g each time.
And (3) clinical observation:
clinical data
The inventor carries out clinical observation and treatment on 160 patients with recurrent oral ulcer; among them, 96 men and 64 women were divided into 80 persons in the observation group and 80 persons in the control group at random.
The patients in the control group are treated by conventional western medicines, and 80 patients in the control group are administered vitamin B2 tablets 10mg 3 times per day; 0.2g metronidazole tablet is taken orally, 3 times a day; the tin powder is blown to the affected part by reed pipes, and the 0.2 percent chlorhexidine gargle is gargled 2-3 times a day and 4 times a day.
The patients in the observation group were treated with the therapeutic agents of the present application.
Criteria for therapeutic effect
And (3) healing: the pain disappears, the oral ulcer is healed, the general symptoms disappear, and the disease does not recur in half a year;
the effect is shown: the pain disappears, the ulcer is healed, the general symptoms disappear, and the disease does not recur in 3 months;
the method has the following advantages: the ulcer is completely cured, the symptom is light and the course of disease is short when the ulcer is relapsed, and the general symptom is relieved;
and (4) invalidation: the oral ulcer has no obvious change before treatment.
The clinical results are as follows:
group of Cure of disease Show effect Is effective Invalidation The total effective rate%
Observation group 55 17 6 2 98
Control group 39 15 15 11 86
The effective rate of the traditional Chinese medicine formula for treating the recurrent oral ulceration is superior to that of the conventional western medicine treatment, the traditional Chinese medicine formula is safe, has no toxic or side effect, treats both heart, spleen, liver and kidney, has an effective treatment effect on the recurrent oral ulceration, can greatly shorten the rehabilitation time, and can improve the immunity of the organism and reduce the recurrence.
The traditional Chinese medicine is prepared from natural traditional Chinese medicine raw materials, is safe, has no toxic or side effect, is warm and clear in combination, can be used for both reinforcing and reducing diarrhea, has the effect of regulating three jiao, treats both heart, spleen, liver and kidney, has an effective treatment effect on recurrent oral ulcer, can greatly shorten the rehabilitation time, can improve the immunity of the organism, and reduces the recurrence.
It will be apparent to those skilled in the art that various changes and modifications may be made in the present invention without departing from the spirit and scope of the invention. Thus, if such modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include such modifications and variations.

Claims (1)

1. The traditional Chinese medicine formula for treating recurrent oral ulcer is characterized by being prepared from the following raw materials in parts by mass: 9g of cape jasmine, 20g of lophatherum gracile, 15g of radix bupleuri, 20g of astragalus membranaceus, 15g of cimicifuga foetida, 12g of bighead atractylodes rhizome, 12g of dried ginger, 15g of codonopsis pilosula, 15g of fructus amomi, 20g of prepared rehmannia root, 12g of golden cypress, 12g of rhizoma anemarrhenae, 12g of moutan bark, 15g of rhizoma alismatis, 12g of dandelion and 12g of liquorice.
CN202111614085.9A 2021-12-27 2021-12-27 Traditional Chinese medicine formula for treating recurrent oral ulcer Withdrawn CN114010754A (en)

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Application Number Priority Date Filing Date Title
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