CN114010377A

CN114010377A - Blood vessel support

Info

Publication number: CN114010377A
Application number: CN202111282450.0A
Authority: CN
Inventors: 李�杰; 常兆华
Original assignee: Shanghai Microport Medical Group Co Ltd
Current assignee: Shanghai Microport Medical Group Co Ltd
Priority date: 2021-11-01
Filing date: 2021-11-01
Publication date: 2022-02-08
Also published as: WO2023072227A1

Abstract

The present invention relates to a vascular stent. The blood vessel support comprises a plurality of support rings and a plurality of connecting rods, the support rings are distributed at intervals along the length direction of the blood vessel support, the connecting rods are connected between two corresponding adjacent support rings, and the wall thickness of at least one part of the connecting rods is smaller than that of the support rings. This blood vessel support can carry out the design of different wall thicknesses in appointed position region, make the adjustment to blood vessel support's detail structure to reach blood vessel support and have the effect of different wall thicknesses, both can guarantee the compliance of attenuate position (being the connecting rod) like this, reduced the production in low shear stress district again, reduced the vortex and produced the probability, reduced the narrow rate of secondary, guaranteed the intensity of all the other positions (being the support ring) that do not attenuate wall thickness simultaneously, make blood vessel support whole still keep good support performance.

Description

Blood vessel support

Technical Field

The invention relates to the technical field of medical instruments, in particular to a vascular stent.

Background

Atherosclerosis is currently considered to be a chronic inflammatory disease that starts from young age and can last for decades, with the clinical symptoms of atherosclerosis usually appearing in adulthood. The basic pathological changes are plaque formation on the inner membrane surface of an artery, and the plaque has lipid stripes, fibrous plaque and atheromatous plaque, and can cause the stenosis or thrombosis of a blood vessel lumen. Among them, the interventional therapy of vascular stents has become a major treatment for such vascular diseases.

However, many studies have shown that after the implantation of the vascular stent, the blood flow pattern near the vascular stent changes when blood flows through, and the fluid environment plays an important role in the repair of the damaged intima of the blood vessel and the generation of restenosis in the stent. Relevant simulation and experiments show that the shear stress of blood on the vessel wall is a key factor influencing restenosis. Because the wave rod of the blood vessel stent protrudes out of the blood vessel wall, the blood can generate separation and reattachment flow when flowing through, the flow velocity is reduced to form a flow stagnation area, the shear stress is also reduced, and the risk of restenosis in the blood vessel stent is greatly increased.

Aiming at the problems, two technical routes are mainly adopted at present, one is to reduce the wall thickness of the intravascular stent, but the integral wall thickness of the intravascular stent has certain defects, the extrusion resistance is reduced due to the reduction of the wall thickness, the intravascular stent cannot provide enough supporting force to prop open lesions, and in addition, the intravascular stent is more fragile along with the reduction of the wall thickness, and is easy to distort and deform when suffering from calcified lesions. The other is to adjust the overall structure of the blood vessel stent, such as adjusting the length of the blood vessel stent, the number of support rings, the number of connecting rods and the like, to improve the intravascular fluid mechanical environment by changing the flexibility of the blood vessel stent, but the blood still has vortex generation when flowing through the blood vessel stent, which generally increases the risk of restenosis in the blood vessel stent.

Disclosure of Invention

In view of the above, it is necessary to provide a vascular stent in view of the above problems.

A vascular stent, comprising: the blood vessel support comprises a plurality of support rings and a plurality of connecting rods, wherein the support rings are distributed at intervals along the length direction of the blood vessel support, the connecting rods are connected between two corresponding adjacent support rings, and the wall thickness of at least one part of the connecting rods is smaller than that of the support rings.

In one embodiment, at least a part of the side of the surface of the connecting rod and/or the support ring that is in contact with the blood flow is streamlined in correspondence with the direction of the blood flow.

In one embodiment, the support rings are formed by connecting support bars, and adjacent support bars are connected by an abutting area and form an angle;

the two ends of the connecting rod are respectively connected with the adjacent areas of the two adjacent supporting rods, the connecting rod is of a nonlinear structure and comprises a warp section and a weft section, and the surfaces of the supporting rods and/or the weft section, which are contacted with blood flow, are streamline smooth surfaces.

In one embodiment, the side wall of the connecting rod close to the central axis of the blood vessel support and/or the side wall of the connecting rod far away from the central axis of the blood vessel support is provided with at least one groove, and the groove is used for enabling the wall thickness of the connecting rod to be smaller than that of the support ring.

In one embodiment, the walls of the recess form rounded transition zones corresponding to the direction of blood flow.

In one embodiment, the support rings are formed by connecting support bars, adjacent support bars are connected by an abutting region and form an angle, and two ends of the connecting bar are respectively connected with the abutting regions of two adjacent support bars;

the notch of the groove is located in the region of the connecting rod and has a rounded chamfer or the rounded chamfer is located at least partially in the abutment region.

In one embodiment, the connecting rod comprises a plurality of grooves, at least one part of the side wall of the connecting rod is in a sine wave or cosine wave structure, and the grooves are formed by the areas, located on the same side wall of the connecting rod, between the adjacent wave troughs and wave crests.

In one embodiment, the troughs on different sidewalls of the connecting rod are aligned.

In one embodiment, the recess located at the axially outermost side of the connecting rod is located at least partially in the abutment region in said support ring.

In one embodiment, the non-recessed area of the connecting rod, or/and the cross section of the support ring along the blood flow direction, is an arc structure protruding towards the central axis of the blood vessel support.

In one embodiment, the thickness of the connecting rod at the bottom of the groove is less than the wall thickness of the support ring and greater than or equal to one-half of the wall thickness of the support ring.

In one embodiment, the connecting rod is further provided with a reinforcement portion, and the wall thickness of the reinforcement portion is larger than that of at least one part of the connecting rod.

In the vascular stent, the wall thickness of at least one part of the connecting rods is smaller than that of the supporting ring, so that the flexibility of the whole vascular stent is increased, the passing rate of the vascular stent in a blood vessel is improved, and the vascular stent is easier to be guided into a diseased position of the blood vessel; the support ring with larger wall thickness can still improve good radial supporting force and ensure the shape of the intravascular stent after expansion. Therefore, the vascular stent can be designed with different wall thicknesses in a designated position area, and the detailed structure of the vascular stent is adjusted to achieve the effect that the vascular stent has different wall thicknesses, so that the flexibility of the thinned position (namely the connecting rod) can be ensured, and the strength of the rest positions (namely the support rings) without the thinned wall thickness is ensured, so that the vascular stent can still maintain good support performance.

Drawings

FIG. 1 is a partial structural view of a vascular stent provided in accordance with an embodiment of the present invention;

FIG. 2 is an enlarged partial schematic view of FIG. 1 at A-A;

FIG. 3 is an enlarged partial schematic view of FIG. 1 at B-B;

FIG. 4 is a partial structural view of a vascular stent provided in accordance with another embodiment of the present invention;

FIG. 5 is a partial schematic view of a vascular stent provided in accordance with another embodiment of the present invention;

FIG. 6 is a partial schematic view of a vascular stent provided in accordance with another embodiment of the present invention;

FIG. 7 is a partial schematic view of a vascular stent provided in accordance with another embodiment of the present invention;

FIG. 8 is a partial schematic view of a vascular stent provided in accordance with another embodiment of the present invention;

FIG. 9 is a schematic cross-sectional view of a connecting rod of a vascular stent provided in accordance with an embodiment of the present invention;

FIG. 10 is a schematic view of the connection rod of the blood vessel stent under the condition of blood flow according to one embodiment of the present invention;

fig. 11 is a schematic structural view of a streamline surface of a connecting rod according to an embodiment of the present invention.

Wherein the reference numerals in the drawings are as follows:

100. a support ring; 110. a support bar; 120. a reinforcement ring; 200. a connecting rod; 210. a groove; 220. a smooth transition zone; 300. a reinforcing portion; A. the vessel wall; B. the blood flow.

Detailed Description

In order to make the aforementioned objects, features and advantages of the present invention comprehensible, embodiments accompanied with figures are described in detail below. In the following description, numerous specific details are set forth in order to provide a thorough understanding of the present invention. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein.

In the description of the present invention, it is to be understood that the terms "central," "longitudinal," "lateral," "length," "width," "wall thickness," "upper," "lower," "front," "rear," "left," "right," "vertical," "horizontal," "top," "bottom," "inner," "outer," "clockwise," "counterclockwise," "axial," "radial," "circumferential," and the like are used in the orientations and positional relationships indicated in the drawings for convenience in describing the invention and to simplify the description, and are not intended to indicate or imply that the referenced device or element must have a particular orientation, be constructed and operated in a particular orientation, and are not to be construed as limiting the invention.

Furthermore, the terms "first", "second" and "first" are used for descriptive purposes only and are not to be construed as indicating or implying relative importance or implicitly indicating the number of technical features indicated. Thus, a feature defined as "first" or "second" may explicitly or implicitly include at least one such feature. In the description of the present invention, "a plurality" means at least two, e.g., two, three, etc., unless specifically limited otherwise.

In the present invention, unless otherwise expressly stated or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integrally formed; can be mechanically or electrically connected; they may be directly connected or indirectly connected through intervening media, or they may be connected internally or in any other suitable relationship, unless expressly stated otherwise. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.

In the present invention, unless otherwise expressly stated or limited, the first feature "on" or "under" the second feature may be directly contacting the first and second features or indirectly contacting the first and second features through an intermediate. Also, a first feature "on," "over," and "above" a second feature may be directly or diagonally above the second feature, or may simply indicate that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature may be directly under or obliquely under the first feature, or may simply mean that the first feature is at a lesser elevation than the second feature.

It will be understood that when an element is referred to as being "secured to" or "disposed on" another element, it can be directly on the other element or intervening elements may also be present. When an element is referred to as being "connected" to another element, it can be directly connected to the other element or intervening elements may also be present. The terms "vertical," "horizontal," "upper," "lower," "left," "right," and the like as used herein are for illustrative purposes only and do not denote a unique embodiment.

An embodiment of the present invention provides a stent for blood vessels, as shown in fig. 1, including: the blood vessel stent comprises a plurality of support rings 100 and a plurality of connecting rods 200, wherein the support rings 100 are distributed at intervals along the length direction of the blood vessel stent, the connecting rods 200 are connected between two corresponding adjacent support rings 100, and the wall thickness of at least one part of the connecting rods 200 is smaller than that of the support rings 100.

The vascular stent can be in a self-expansion type or a balloon expansion type. The vessel stent may be cut from a metal tube, that is, the connecting rod 200 and the support ring 100 of the vessel stent are integrally formed, but in other embodiments, the connecting rod 200 and the support ring 100 of the vessel stent may also be connected by welding or the like. The vascular stent has biocompatibility, and the material of the vascular stent can be degradable or non-degradable.

As an example, as shown in FIG. 1, the support ring 100 may be formed by connecting a plurality of support rods 110 end to end, and may have a wave shape, which mainly serves to support a blood vessel. Wherein the wall thickness of the support bar 110 is 0.08 mm-0.2 mm, and the adjacent support bars 110 are connected by the adjacent regions 120 and form an angle (see fig. 1). The connecting rod 200 mainly plays a role of connecting the support rings 100 and is a key factor influencing the overall flexibility of the vascular stent. In some embodiments, the two ends of the connecting rod 200 are respectively connected with the adjacent regions 120 of the two adjacent supporting rods 110, the wall thickness of the connecting rod 200 is reduced, and then the connecting rod is more easily bent, the flexibility of the vascular stent is enhanced, the vascular stent can be more favorably attached to the vascular wall A, and the tilting injury of the vascular stent to the intima after the expansion of the vascular stent is avoided. Meanwhile, the side wall of the connecting rod 200 close to the central axis of the vascular stent is in contact with blood, and when the blood flows through the connecting rod 200, the wall thickness is reduced, so that the shearing stress of the blood on the vascular wall A is improved, and the vascular restenosis can be effectively avoided.

It should be noted that the entire wall thickness of the connecting rod 200 is not required to be smaller than that of the support ring 100, and it is also possible that the wall thickness of a part of the connecting rod 200 is smaller than that of the support ring 100, as long as the compliance and radial supporting force of the blood vessel stent are ensured, for example, the wall thickness of the connecting rod 200 only near the end of the abutting region 120 of the support rod 110 is equal to that of the support rod 110, and the thickness of the other parts of the connecting rod 200 is smaller than that of the support rod 110.

In the vascular stent, the wall thickness of at least one part of the connecting rod 200 is smaller than that of the support ring 100, so that the flexibility of the vascular stent can be increased while the anti-extrusion property of the vascular stent is maintained, the passing rate of the vascular stent in a blood vessel is improved, and the vascular stent can be guided to a lesion position of the blood vessel more easily; the support ring 100 with a larger wall thickness can still improve good radial support force and ensure the shape of the intravascular stent after expansion. Therefore, the vascular stent can be designed with different wall thicknesses in a designated position area, and the detailed structure of the vascular stent is adjusted to achieve the effect that the vascular stent has different wall thicknesses, so that the flexibility of the thinned position (namely the connecting rod 200) can be ensured, and the strength of the rest positions (namely the support ring 100) without the thinned wall thickness is ensured, so that the vascular stent can still maintain good support performance.

In some embodiments of the invention, at least a portion of the blood flow contacting surface side of the connecting rod 200 and/or the support ring 100 is streamlined corresponding to the blood flow direction. The connecting rod 200 and the side of the surface of the support ring 100 contacting the blood flow are arranged to have a streamline structure corresponding to the blood flow direction, for example, the connecting rod 200 has a streamline structure on the side contacting the blood flow in the axial direction, and for example, the abutting region 120 of the support ring 100 has a streamline structure on the side contacting the blood flow, and in some embodiments, the surface of the abutting region 120 on the side contacting the blood flow is arc-shaped. Therefore, the probability of the blood flow generating vortex in the blood vessel support can be reduced, the hydrodynamic environment of the blood vessel support is improved, the generation probability of a low shear stress area is reduced, and the secondary stenosis rate is reduced. The connecting rod 200 and/or the support ring 100 refers to one of the following combinations: (1) the connecting rod 200, (2) the support ring 100, (3) the connecting rod 200 and the support ring 100, including the joint of the connecting rod 200 and the support ring 100, namely the abutting region 120; preferably, the surface of the connecting rod 200 may be streamlined, and the streamline structure extends to the support ring 100. It should be noted that when the surface of the support ring 100 is streamlined, the "thickness of the support ring 100" refers to the maximum thickness of the support ring 100, and in some embodiments, the thickness of the support ring 100 is uniform. The expression "corresponding to the blood flow direction" means that the drag reduction target direction of the streamline structure surface is the blood flow direction or the blood flow approximate direction, that is, "corresponding to the blood flow direction being streamline" means that the blood flow resistance of the vascular stent can be reduced in the blood flow direction, and in this embodiment, the trend of the streamline surfaces of the connecting rod 200 and the support ring 100 is the same or approximately the same as the blood flow direction.

In the following, the connecting rod 200 is taken as an example and described in terms of a streamlined surface, see fig. 11, the surface satisfying the following condition is called a streamlined surface: (1) the surface structure is smooth and has no edges and corners in a specific direction; (2) the climbing angle is more than or equal to 135 degrees and less than 180 degrees, wherein the climbing angle refers to an included angle between a connecting line between the lowest point and the highest point of the slope and the inner wall of the connecting rod 200; (3) the distance between the lowest point and the highest point of the slope surface cannot be less than half of the total wall thickness of the connecting rod 200.

In particular, in some embodiments of the present invention, as shown in fig. 1, the support ring 100 is formed by connecting a plurality of support bars 110, and adjacent support bars 110 are connected by an abutting region 120 and form an angle; the two ends of the connecting rod 200 are respectively connected with the adjacent regions 120 of two adjacent supporting rods 120, the connecting rod 200 is of a nonlinear structure and comprises a warp section and a weft section, and the surfaces of the supporting rods 110 and/or the weft section contacting blood flow are streamline smooth surfaces. The streamline smooth surface can mean that the cross section of the connecting rod 200 along the blood flow direction is streamline, and comprises a round shape, a semicircular shape and an arc shape, so that when blood flows through the surfaces of the supporting rod 110 and the connecting rod 200, the resistance of the supporting rod 110 and the connecting rod 200 to the blood flow can be greatly reduced. Preferably, the streamlined smooth surface extends from the connecting rod 200 to the portion of the support rod 110. It should be noted that the meridian section of the connecting rod 200 refers to the portion of the connecting rod 200 perpendicular to the blood flow direction, and the latitudinal section refers to the portion of the connecting rod 200 parallel or approximately parallel to the blood flow direction.

In some embodiments of the present invention, as shown in fig. 2, 3, 5 to 8, the side wall of the connecting rod 200 close to the central axis of the blood vessel stent (i.e. the side close to the blood flow) and/or the side wall far from the central axis of the blood vessel stent has a groove 210, and the groove 210 is used for making the wall thickness of the connecting rod 200 smaller than that of the support ring 100. In this way, the connecting rod 200 having a smaller wall thickness than the support ring 100 does not need to be disposed on the support ring 100, and the length and position of the region with a thinner wall thickness on the connecting rod 200 can be flexibly designed according to the actual situation. During application, according to specific practical conditions, whether the groove 210 is arranged on the side wall of the connecting rod 200 close to the central axis of the vascular stent (see fig. 2 and 6), or whether the groove 210 is arranged on the side wall of the connecting rod 200 far from the central axis of the vascular stent (see fig. 3 and 7), or whether the grooves 210 are arranged on the side walls of the connecting rod 200 far from and close to the central axis of the vascular stent (see fig. 5 and 8), can be selected, wherein when the grooves 210 are arranged on the two side walls of the connecting rod 200, the stress of the connecting rod 200 is uniform, and the stability of the vascular stent is improved.

In some embodiments of the present invention, as shown in fig. 2 and 3, the walls of the groove 210 form a rounded transition area 220 corresponding to the blood flow direction. The smooth transition can make the recess 210 that is located on the lateral wall that connecting rod 200 is close to the vascular support axis locate can not form the vortex, has reduced the restenosis rate to and make the recess 210 that is located on the lateral wall that connecting rod 200 is far away from the vascular support axis locate can not harm the tunica intima, reduces the intimal hyperplasia. It should be noted that the entire sidewall area of the groove 210 is the rounded transition area 220.

In particular, in some embodiments of the present invention, the notch of the groove 210 is located in the connecting rod region and has a rounded chamfer, or the rounded chamfer is located at least partially in the abutment region 120, and/or the groove 210 has a rounded chamfer between the groove wall and the groove bottom. It will be appreciated that in some embodiments the rounded chamfer forms part of the rounded transition. It should be noted that, when the groove 210 is formed as a recessed area along the length of the connecting rod 200 on either side surface of the connecting rod 200, in one embodiment, the groove 210 is at least partially located in the abutting area 120 of the supporting rod 110, and at this time, the rounded corner of the notch of the groove 210 is located in the abutting area 120 of the supporting rod 110; in another embodiment, the notch of the groove 210 itself has a rounded corner disposed on the connecting rod 200 when the entire groove 210 is located on either side of the surface of the connecting rod 200. The round chamfer can prevent the groove 210 on the side wall of the connecting rod 200 close to the central axis of the vascular stent from forming a vortex, reduce the restenosis rate, prevent the groove 210 on the side wall of the connecting rod 200 far away from the central axis of the vascular stent from damaging the intima of the blood vessel, and reduce the intimal hyperplasia.

On the premise that the connecting rod 200 has the groove 210, as shown in fig. 6 to 8, in some embodiments of the present invention, the connecting rod 200 includes a plurality of grooves 210, at least a portion of the sidewall of the connecting rod 200 has a sine wave or cosine wave structure, and the groove 210 is formed in a region between adjacent wave troughs and wave crests of the same sidewall of the connecting rod 200. The groove 210 of this type of structure can effectively reduce the wall thickness of the connecting rod 200, and the groove of this type of structure is smooth everywhere. It should be noted that, when the two side walls of the connecting rod 200 away from and close to the central axis of the intravascular stent are both provided with the grooves 210, the peaks on the two side walls are distributed in a staggered manner to ensure that the wall thickness of the connecting rod 200 is effectively reduced.

Specifically, as shown in FIG. 8, the valleys at the different sidewalls of the connecting rod 200 are aligned. Thus, the wall thickness of the connecting rod 200 can be effectively reduced, and the connecting rod 200 is uniformly stressed.

In particular, as shown in fig. 6 to 8, the recess 210 located at the axially outermost side of the connecting rod 200 is located at least partially in the abutment region 120 in the support ring 100. The axial direction herein refers to the longitudinal direction of the connecting rod 200. It should be noted that, when the grooves 210 of the sine wave or cosine wave structure generate the recessed areas on either side surface of the whole connecting rod 200 along the length direction of the connecting rod 200, i.e. the sine wave and cosine wave are completely located in the range of the connecting rod 200, and the smooth transition area 220 is completely located in the range of the connecting rod 200. In another embodiment, when the grooves 210 of sine wave or cosine wave structure are recessed beyond either side surface of the entire connecting rod 200, the wall of the outermost groove 210 extends to the adjacent region 120 of the support ring 100, and the rounded transition region 220 is partially located at the adjacent region 120. The smooth transition or the smooth transition can prevent the formation of eddy current at the groove 210 on the side wall of the connecting rod 200 near the central axis of the stent, thereby reducing the restenosis rate.

In the case of the connecting rod 200 having the groove 210, as shown in fig. 9 and 10, in some embodiments of the present invention, the cross section of the non-groove region, the supporting rod 110 or the adjacent region 120 (not shown) of the connecting rod 200 in the blood flow direction is an arc structure protruding toward the central axis of the stent. The cross section of the non-groove area of the support ring 100 and the connecting rod 200 is designed to be an arc structure, so that the outer wall of the cross section is smooth compared with the rectangular cross section, when blood flows through the blood vessel stent, no vortex is formed, the generation of a low shear stress area is avoided, and the probability of restenosis in the blood vessel stent is reduced.

In some embodiments of the invention, at least a portion of the connecting rod 200 has a wall thickness less than the wall thickness of the support ring 100 and greater than or equal to one-half the wall thickness of the support ring 100, and the connecting rod 200 has a thickness at the bottom of the groove less than the wall thickness of the support ring 100 and greater than or equal to one-half the wall thickness of the support ring 100, it being understood that the thickness of the support ring 100 is a uniform thickness when the groove 210 does not extend beyond the range of the connecting rod 200. For example, one-half, two-thirds, three-quarters, etc. of the wall thickness of the support ring 100 may be provided. For example, when the wall thickness of the support bar 110 of the support ring 100 is 0.1mm, the wall thickness of the connection bar 200 at the bottom of the groove may be 0.05mm to 0.07 mm. Thus, the strength of the connecting rod 200 can be ensured, and the generation of the eddy phenomenon at the connecting rod 200 can be suppressed.

In some embodiments of the present invention, as shown in fig. 1 and 4, the connecting rod 200 is further provided with a reinforcement 300, and the wall thickness of the reinforcement 300 is greater than the wall thickness of at least a portion of the connecting rod 200. The wall thickness of the reinforcing part 300 may be the same as that of the support bar 110 of the support ring 100, so that the connecting bar 200 may have sufficient strength to ensure the crush resistance of the stent. Alternatively, the shape of the reinforcement 300 may be a horizontally disposed "S" shape, a wave shape, a fold line shape, or the like. Alternatively, one end of the reinforcement 300 is connected to the connection rod 200, and the other end of the reinforcement 300 is connected to the reinforcement ring 120 of the support ring 100.

In order to describe the structure of the vascular stent in more detail, 7 examples are given below.

Example 1

As shown in fig. 1 to 3, the present embodiment provides a middle blood vessel stent, which includes a plurality of support rings 100 and a plurality of connecting rods 200; the support rings 100 are spaced apart along the central axis of the stent, and the two ends of the connecting rod 200 are connected to the adjacent regions 120 of two adjacent support rods 110. Wherein, the support ring 100 is formed by connecting a plurality of support bars 110 end to end, and the wall thickness D1 of the support bar 110 is 0.1 mm. A groove 210 is formed on a part of the side wall of the connecting rod 200 close to the central axis of the stent, the distance D2 between the groove bottom of the groove 210 and the side wall of the connecting rod 200 far from the central axis of the stent (i.e. the wall thickness of the connecting rod 200) is 0.05m, the groove 210 does not exceed any side surface of the connecting rod 200, the groove wall of the groove 210 forms a smooth transition area 220 corresponding to the blood flow direction, the notch of the groove 210 is located in the connecting rod area and has a round chamfer angle, and a round chamfer angle is formed between the notch of the groove 210 and the groove bottom.

Example 2

As shown in fig. 4 and 5, the present embodiment provides a middle blood vessel stent, which includes a plurality of support rings 100 and a plurality of connecting rods 200; the support rings 100 are spaced apart along the central axis of the stent. Wherein, the support ring 100 is formed by connecting a plurality of support bars 110 end to end, and the wall thickness D1 of the support bar 110 is 0.1 mm. One end of the connecting rod 200 is connected to the adjoining regions 120 of two adjacent support bars 110, and the other end of the connecting rod 200 is connected to the adjoining regions 120 of two adjacent support bars 110 by a reinforcing part 300, the reinforcing part 300 having a horizontally disposed "S" shape. The side wall of the connecting rod 200 far from the central axis of the vascular stent is provided with a groove 210, the distance D2 between the groove bottom of the groove 210 and the side wall of the connecting rod 200 near the central axis of the vascular stent (namely the wall thickness of the connecting rod 200) is 0.05m, the groove 210 does not generate a concave area beyond any side surface of the whole range of the connecting rod 200, the groove wall of the groove 210 forms a smooth transition area 220 corresponding to the blood flow direction, the notch of the groove 210 and the groove wall and the groove bottom which are positioned in the connecting rod area and provided with a round chamfer angle, and the round chamfer angle is arranged between the groove wall and the groove bottom of the groove 210.

Example 3

As shown in fig. 5, the present embodiment provides a blood vessel stent, which comprises a plurality of support rings 100 and a plurality of connecting rods 200; the support rings 100 are spaced apart along the central axis of the stent. Wherein, the support ring 100 is formed by connecting a plurality of support bars 110 which are connected end to end, and the wall thickness D1 of the support bars 110 is 0.1 mm; both ends of the connecting rod 200 are connected to the adjoining regions 120 of two adjacent support bars 110, respectively. The two side walls of the connecting rod 200 far from and near the central axis of the vascular stent are respectively provided with a groove 210, the two grooves 210 are distributed in an aligned manner, the distance D2 between the groove bottoms (namely the wall thickness of the connecting rod 200) is 0.05mm, the groove 210 does not exceed the surface of any side of the whole range of the connecting rod 200 to generate a concave area, the groove wall of the groove 210 forms a smooth transition area 220 corresponding to the blood flow direction, the notch of the groove 210 and the groove wall and the groove bottom which are positioned in the connecting rod area and are provided with round chamfers, and the round chamfers are arranged between the groove wall and the groove bottom of the groove 210.

Example 4

As shown in fig. 6, the present embodiment provides a blood vessel stent, which comprises a plurality of support rings 100 and a plurality of connecting rods 200; the support rings 100 are spaced apart along the central axis of the stent. Wherein, the support ring 100 is formed by connecting a plurality of support bars 110 which are connected end to end, and the wall thickness D1 of the support bars 110 is 0.1 mm; both ends of the connecting rod 200 are connected to the adjoining regions 120 of two adjacent support bars 110, respectively. The side wall of the connecting rod 200 far from the central axis of the vessel stent has a plurality of grooves 210 and is in a sine wave structure, the side wall has 2 troughs and 1 peak, the distance D3 between adjacent troughs and peaks is 0.05m, and the two grooves located at the outermost side of the connecting rod in the axial direction are located in the adjacent region 120 of the support ring 100.

Example 5

As shown in fig. 7, the present embodiment provides a blood vessel stent, which comprises a plurality of support rings 100 and a plurality of connecting rods 200; the support rings 100 are spaced apart along the central axis of the stent. Wherein, the support ring 100 is formed by connecting a plurality of support bars 110 which are connected end to end, and the wall thickness D1 of the support bars 110 is 0.1 mm; both ends of the connecting rod 200 are connected to the adjoining regions 120 of two adjacent support bars 110, respectively. The side wall of the connecting rod 200 far from the central axis of the vascular stent has a plurality of grooves 210 and is in a cosine wave structure, and has 3 troughs and 2 peaks, the distance D3 between adjacent troughs and peaks is 0.05m, and the two grooves at the outermost side of the connecting rod in the axial direction are both located in the adjoining region 120 of the support ring 100.

Example 6

As shown in fig. 8, the present embodiment provides a blood vessel stent, which comprises a plurality of support rings 100 and a plurality of connecting rods 200; the support rings 100 are spaced apart along the central axis of the stent. Wherein, the support ring 100 is formed by connecting a plurality of support bars 110 which are connected end to end, and the wall thickness D1 of the support bars 110 is 0.1 mm; both ends of the connecting rod 200 are connected to the adjoining regions 120 of two adjacent support bars 110, respectively. The lateral wall that connecting rod 200 kept away from and is close to vascular support axis all is provided with a plurality of recesses 210 and is cosine wave structure, all has 2 troughs and 1 crest, and the trough that is located both sides aligns and the distance D4 between two troughs of aligning is 0.05mm, and two recesses that are located the connecting rod axial outermost on each lateral wall of connecting rod 200 all are located the adjacent region 120 in support ring 100.

Example 7

As shown in fig. 9, the present embodiment provides a blood vessel stent, which is different from embodiment 1 in that the cross-sections of the non-recessed areas of the support rods 110 and the connecting rods 200 of the support ring 100 of the present embodiment are arranged in an arc-shaped structure protruding toward the central axis of the blood vessel stent.

The technical features of the embodiments described above may be arbitrarily combined, and for the sake of brevity, all possible combinations of the technical features in the embodiments described above are not described, but should be considered as being within the scope of the present specification as long as there is no contradiction between the combinations of the technical features.

The above-mentioned embodiments only express several embodiments of the present invention, and the description thereof is more specific and detailed, but not construed as limiting the scope of the invention. It should be noted that, for a person skilled in the art, several variations and modifications can be made without departing from the inventive concept, which falls within the scope of the present invention. Therefore, the protection scope of the present patent shall be subject to the appended claims.

Claims

1. A vascular stent, characterized in that it comprises: the blood vessel support comprises a plurality of support rings and a plurality of connecting rods, wherein the support rings are distributed at intervals along the length direction of the blood vessel support, the connecting rods are connected between two corresponding adjacent support rings, and the wall thickness of at least one part of the connecting rods is smaller than that of the support rings.

2. Vessel support according to claim 1, characterized in that at least a part of the side of the surface of the connecting rods and/or of the support rings which is in contact with the blood flow is streamlined in correspondence with the direction of the blood flow.

3. The vascular stent of claim 2, wherein the support rings are formed by struts connected, adjacent struts being connected by abutting regions and forming an angle;

4. A vascular stent according to any one of claims 1 to 3, wherein the side wall of the connecting rod close to the central axis of the vascular stent and/or the side wall of the connecting rod far from the central axis of the vascular stent has at least one groove for making the wall thickness of the connecting rod smaller than that of the support ring.

5. The vascular stent of claim 4, wherein the walls of the groove form rounded transition zones corresponding to the direction of blood flow.

6. The vessel support according to claim 4, wherein the support rings are formed by connecting support bars, adjacent support bars are connected by an abutting region and form an angle, and two ends of the connecting bar are respectively connected with the abutting regions of two adjacent support bars;

7. The vascular stent of claim 4, wherein the groove has a rounded chamfer between the groove wall and the groove bottom.

8. The blood vessel support according to claim 4, wherein the connecting rod comprises a plurality of grooves, at least a part of the side wall is in a sine wave or cosine wave structure, and the grooves are formed by the adjacent regions between the wave troughs and the wave crests on the same side wall of the connecting rod.

9. The vascular stent of claim 8, wherein the troughs on different sidewalls of the connecting rods are aligned.

10. A vascular stent as in claim 7, wherein the grooves located on the axially outermost sides of the tie bars are located at least partially in the abutment regions in the support rings.

11. The vessel support according to claim 4, wherein the non-recessed areas of the connecting rods, or/and the cross-section of the support ring in the direction of blood flow, are arc-shaped structures that are convex towards the central axis of the vessel support.

12. The vascular stent of claim 4, wherein the thickness of the connecting rods at the bottom of the slots is less than the support ring wall thickness and greater than or equal to one-half of the support ring wall thickness.

13. The vascular stent of claim 1, wherein the connecting rod is further provided with a reinforcement, and the wall thickness of the reinforcement is greater than the wall thickness of at least a portion of the connecting rod.