CN114009647A - Preparation method of inonotus obliquus granule beverage - Google Patents
Preparation method of inonotus obliquus granule beverage Download PDFInfo
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- CN114009647A CN114009647A CN202111370800.9A CN202111370800A CN114009647A CN 114009647 A CN114009647 A CN 114009647A CN 202111370800 A CN202111370800 A CN 202111370800A CN 114009647 A CN114009647 A CN 114009647A
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Images
Classifications
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/385—Concentrates of non-alcoholic beverages
- A23L2/39—Dry compositions
- A23L2/395—Dry compositions in a particular shape or form
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L2/00—Non-alcoholic beverages; Dry compositions or concentrates therefor; Their preparation
- A23L2/52—Adding ingredients
- A23L2/60—Sweeteners
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
- C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
- C08B37/0003—General processes for their isolation or fractionation, e.g. purification or extraction from biomass
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Abstract
The invention relates to the technical field of food and medicine production, and discloses a preparation method of inonotus obliquus granule beverage, which comprises the following steps: s1, taking the inonotus obliquus, cleaning, drying, weighing, and crushing for later use; s2, leaching the crushed inonotus obliquus to obtain an extracting solution, performing deproteinization and decoloration treatment on the extracting solution, preparing a solid after treatment, and weighing the solid; s3, mixing the extract with a fixed weight with a diluent, a flavoring agent, an adhesive and the like, and concentrating into paste; s4, drying the obtained paste, sieving and granulating. The inonotus obliquus is prepared into the granule beverage, so that the diabetes mellitus can be prevented or treated by drinking of most people, the inonotus obliquus is a pure natural substance, the problem of drinking metering cannot exist, no side effect is caused to a body after drinking, the carrying is more convenient by the mode of the granule beverage, the polysaccharide in the inonotus obliquus is extracted by an extraction method, and the blood sugar reducing effect is better.
Description
Technical Field
The invention relates to the technical field of food and medicine production, and particularly relates to a preparation method of a inonotus obliquus granule beverage.
Background
The inonotus obliquus, also called inonotus obliquus and birch gall, grows at the wound of living standing birch, forms an infertile tumor-like sclerotium like human body cancer, and as the tumor gradually grows after absorbing birch serous fluid, the birch finally withers and dies, so the inonotus obliquus is also called as inonotus obliquus.
The prevalence rate of diabetes is 9.7%, 67% of patients with diabetes do not know to get diabetes themselves, so that more serious complications caused by early treatment are avoided, the mycelium of the inonotus obliquus and the water-soluble and water-insoluble polysaccharide extracted from sclerotia have the effect of reducing blood sugar, the effect of reducing blood sugar is obvious and durable, the inonotus obliquus can also reduce the blood pressure of large artery, small artery and capillary vessel to a certain extent, maintain the blood pressure in a normal range, and protect tissues and organs,
substances with effects in the inonotus obliquus are mainly polysaccharides, the polysaccharides are not extracted from numerous products at present, but the inonotus obliquus is simply added, so that the hypoglycemic effect is very limited, the inonotus obliquus can be wasted, and the diabetic patients can cause hemolytic anemia, leucopenia and other side effects after taking hypoglycemic drugs for a long time.
Disclosure of Invention
In order to overcome the defects in the prior art, the invention provides a preparation method of inonotus obliquus granule beverage, and the technical problems to be solved by the invention are as follows: the long-term administration of hypoglycemic drugs can cause side effects, and the polysaccharide in the inonotus obliquus is not extracted sufficiently, so that the hypoglycemic effect is limited.
The preparation method of the inonotus obliquus granule beverage comprises the following steps:
s1, taking the inonotus obliquus, cleaning, drying, weighing, and crushing for later use;
s2, leaching the crushed inonotus obliquus to obtain an extracting solution, performing deproteinization and decoloration treatment on the extracting solution, preparing a solid after treatment, and weighing the solid;
s3, mixing the extract with a fixed weight with a diluent, a flavoring agent, an adhesive and the like, and concentrating into paste;
s4, drying the obtained paste, sieving and granulating.
In a preferred embodiment, the inonotus obliquus is extracted by an extraction method, the material-liquid ratio of the inonotus obliquus in the extraction method is 1:33, the extraction temperature is 80 ℃, the extraction time is 2.2 hours, and the extraction frequency of the inonotus obliquus is set to two times, under the control of the material-liquid ratio, the temperature and the extraction time, after the two times of extraction, the extraction rate of the polysaccharide is 24.578%, most of the polysaccharide in the inonotus obliquus is extracted, the cost is high when the remaining polysaccharide is extracted, so the remaining polysaccharide and the inonotus obliquus are used for other purposes, the extraction rate is high, and the cost is reduced.
In a preferred embodiment, the polysaccharide in the inonotus obliquus can be extracted by an alcohol precipitation extraction method, the solid-liquid ratio is 1:15, the extraction time is 90 minutes, the extraction frequency of the inonotus obliquus is set to be two times, the crude drug concentration is 1.0g/ml, and the final ethanol concentration is 65%.
In a preferred embodiment, the crude polysaccharide extracted from the extracting solution is subjected to deproteinization treatment, and the deproteinization treatment is performed by adopting a polyamide chromatographic adsorption column chromatography, so that the protein removal rate reaches 95.2%, the polysaccharide retention rate is 89.7%, protein is remained in the polysaccharide after extraction, the protein can interfere with the structure and activity of the polysaccharide, and the protein in the polysaccharide is removed, so that the blood sugar reducing effect of the polysaccharide after being prepared into granules can be improved, and the curative effect of the product can be improved.
In a preferred embodiment, the crude polysaccharide extracted from the extracting solution is subjected to decolorization treatment, pigment in the polysaccharide is removed, the decolorization treatment is performed by using AB-8 resin, the pH is 4.0, the temperature is set to be 60 ℃, the decolorization rate of the crude polysaccharide is 87.38%, the retention rate of the polysaccharide is 89.24%, the removal rate of protein is 77.11%, the pigment contained in the inonotus obliquus polysaccharide can seriously influence the separation and purification, the chemical structure and the action mechanism of the inonotus obliquus polysaccharide, the prepared finished product is a granule beverage, the drinking idea can be reduced when the color is poor, and after the pigment is removed, the using effect of the polysaccharide is increased, so that the purchasing desire and drinking drive of customers are increased.
In a preferred embodiment, the water content of the washed and dried inonotus obliquus is less than 1.5%, and the crushed inonotus obliquus is sieved by a 100-mesh sieve.
In a preferred embodiment, the diluent is microcrystalline cellulose and xylitol, the proportion of the inonotus obliquus extract to the diluent is 100:10, the flavoring agent is a sweetening agent, the main substances are one or more of simple syrup, sucrose and modified starch carbohydrate, the proportion of the inonotus obliquus extract to the flavoring agent is 100:5, the adhesive is absolute ethyl alcohol, the flavoring agent is added into polysaccharide extracted from the inonotus obliquus, the taste of the inonotus obliquus granules is favorably improved when the inonotus obliquus granules are drunk, the particles are favorably formed by adding the adhesive, the inonotus obliquus granules are conveniently prepared, and the inonotus obliquus granules have better taste, are convenient to sell and improve the experience of customers.
In a preferred embodiment, when the Inonotus obliquus paste is granulated, the drying temperature of the paste is 70 ℃, the paste is granulated into granules through a sieve with 16 meshes and is granulated into whole granules through a sieve with 12 meshes, the granules are completely dried at the temperature of 60-80 ℃, and the drying temperature is gradually increased in the process.
In a preferred embodiment, black fungus, Chinese yam, bovine colostrum and sweet potato can be added into the inonotus obliquus granules, and the components are as follows: 25 parts of inonotus obliquus, 3 parts of Chinese yam, 2 parts of bovine colostrum and 5 parts of sweet potato.
In a preferred embodiment, when the polysaccharide is extracted from the inonotus obliquus, the polysaccharide can be extracted by a physical method which comprises the following steps: the technical parameters of the high-voltage pulse electric field assisted extraction of the inonotus obliquus polysaccharide comprise: the electric field intensity is 30kV/cm, the pulse number is 6, and the solid-liquid ratio is 1: 25, pH value is 10; when ultrasonic-assisted extraction is carried out, the process parameters are as follows: ultrasonic treatment time is 70min, temperature is 80 ℃, frequency is 20kHz, and solid-to-liquid ratio is 1: 12; when the microwave is used for assisting, the microwave power is 88-96W.
The invention has the technical effects and advantages that:
1. the inonotus obliquus is prepared into the electuary beverage, so that most people can prevent or treat diabetes by drinking, the inonotus obliquus is a pure natural substance, the problem of drinking metering cannot exist, no side effect is caused to the body after drinking, and the inonotus obliquus has small volume and is more convenient to carry by means of the electuary beverage;
2. the polysaccharide in the inonotus obliquus is extracted by an extraction method, and the temperature, the proportion and the time during extraction are controlled, so that the extraction amount of the polysaccharide in the inonotus obliquus is favorably improved;
3. according to the invention, the extract of the inonotus obliquus is dried and then weighed again, so that the quality of the polysaccharide in the inonotus obliquus can be accurately controlled, and the rest substances such as a diluent, a flavoring agent and the like are added subsequently to prepare the granules, so that the proportion of the polysaccharide in the granules can be accurately known, and the proper amount of the polysaccharide can be conveniently taken to control the blood sugar;
4. the taste of the inonotus obliquus granules is favorably improved by adding the flavoring agent into the polysaccharide extracted from the inonotus obliquus, the granules are favorably formed by adding the adhesive, the inonotus obliquus granules are conveniently prepared, and the inonotus obliquus granules have better taste and are convenient to sell and drink.
Drawings
FIG. 1 is a schematic view of the preparation process of the present invention.
Detailed Description
The technical solution of the present invention will be clearly and completely described below with reference to the accompanying drawings of the present invention, and the forms of the structures described in the following embodiments are merely examples, and the method for preparing a fuscoporia obliqua granule beverage according to the present invention is not limited to the structures described in the following embodiments, and all other embodiments obtained by a person skilled in the art without creative efforts fall within the scope of the present invention.
The first embodiment is as follows: referring to fig. 1, the invention provides a preparation method of inonotus obliquus granule beverage, comprising the following steps:
s1, taking the inonotus obliquus, cleaning, drying, weighing, and crushing for later use;
s2, leaching the crushed inonotus obliquus to obtain an extracting solution, performing deproteinization and decoloration treatment on the extracting solution, preparing a solid after treatment, and weighing the solid;
s3, mixing the extract with a fixed weight with a diluent, a flavoring agent, an adhesive and the like, and concentrating into paste;
s4, drying the obtained paste, sieving and granulating.
Referring to fig. 1, the inonotus obliquus is extracted to obtain the polysaccharide inside the inonotus obliquus by an extraction method, the material-liquid ratio of the inonotus obliquus in the extraction method is 1:33, the extraction temperature is 80 ℃, the extraction time is 2.2 hours, the extraction frequency of the inonotus obliquus is set to be two times, by extracting the inonotus obliquus twice, most of the polysaccharide in the inonotus obliquus can be extracted, the waste of the inonotus obliquus is reduced, the extraction efficiency and the extraction effect of the polysaccharide are improved by controlling the parameters of the inonotus obliquus in the extraction process, the residue is reduced, and the produced electuary is better in effect.
Referring to fig. 1, the polysaccharide in the inonotus obliquus can be extracted by an alcohol precipitation extraction method, the solid-to-liquid ratio is 1:15, the extraction time is 90 minutes, the extraction frequency of the inonotus obliquus is set to two times, the crude drug concentration is 1.0g/ml, the final ethanol concentration is 65%, the polysaccharide is extracted by the alcohol precipitation extraction method, the preparation time is shorter, the ethanol in the extracting solution needs to be treated and then can be used, therefore, the production mode can be selected according to the time condition, and the practicability is higher.
Referring to fig. 1, crude polysaccharide extracted from the extracting solution is deproteinized by polyamide chromatography, the protein removal rate reaches 95.2%, the polysaccharide retention rate is 89.7%, the protein in the polysaccharide is removed by a physical method, a large amount of organic reagents are avoided, and the treated polysaccharide does not contain organic solvents, so that the subsequent administration does not affect the body, most of the protein is dragged out after the crude polysaccharide is treated, the polysaccharide retention rate is high, and the activity of the polysaccharide is improved.
Referring to fig. 1, crude polysaccharide extracted from an extracting solution is decolorized, pigments in the polysaccharide are removed, AB-8 resin is used for decolorization, the pH is 4.0, the temperature is set to be 60 ℃, the decolorization rate of the crude polysaccharide is 87.38%, the retention rate of the polysaccharide is 89.24%, the removal rate of protein is 77.11%, the resin is used for decolorization, other organic matters cannot be mixed in the decolorization process, the purity of the polysaccharide in the inonotus obliquus is favorably maintained, the decolorization rate is high, meanwhile, the excellent deproteinization treatment is achieved, the activity of the polysaccharide after the deproteinization and the decolorization treatment is high, the action mechanism cannot be influenced, and the blood sugar reducing effect of the granules is improved.
Referring to fig. 1, the water content of the washed and dried inonotus obliquus is below 1.5%, the inonotus obliquus is crushed and then passes through a 100-mesh screen, the particle size of the inonotus obliquus is controlled after the inonotus obliquus is dried and crushed, the leaching efficiency of polysaccharide in the inonotus obliquus is improved, and the hypoglycemic effect of the inonotus obliquus granules is achieved.
Referring to fig. 1, the diluent is microcrystalline cellulose and xylitol, the proportion of the inonotus obliquus extract to the diluent is 100:10, the flavoring agent is a sweetening agent, the main substances are one or more of simple syrup, sucrose and modified starch carbohydrate, the proportion of the inonotus obliquus extract to the flavoring agent is 100:5, the binding agent is absolute ethyl alcohol, the diluent and the binding agent are adopted, so that polysaccharides in the inonotus obliquus can be favorably prepared into impact particles, the sweetening agent is added, the prepared granules have good taste when being drunk, and the taste of pine which is not accepted by part of the inonotus obliquus can be removed.
Referring to fig. 1, when the inonotus obliquus paste is granulated, the drying temperature of the paste is 70 ℃, granules are prepared through a 16-mesh sieve, the granules are prepared through a 12-mesh sieve, the granules are completely dried at the temperature of 60-80 ℃, the drying temperature is gradually increased in the process, the inonotus obliquus granules are dried in a gradual temperature rise mode, a layer of hard film is prevented from being formed after the surfaces of the granules are dried, the water content inside the granules is positive three, and sugar in the granules is melted when meeting high temperature suddenly, so that the granules become hard and even disintegrate.
Referring to fig. 1, black fungus, Chinese yam, bovine colostrum and sweet potato can be added into the inonotus obliquus granules, and the components are as follows: the instant drink is prepared from the raw materials of 25 parts of inonotus obliquus, 3 parts of Chinese yam, 2 parts of bovine colostrum and 5 parts of sweet potato, wherein the black fungus, the Chinese yam and the sweet potato all have a certain blood sugar reducing effect, the bovine colostrum has the effect of regulating blood sugar, the taste of the instant drink can be enriched by the black fungus, the Chinese yam, the bovine colostrum and the sweet potato in the world when the instant drink is drunk, and the added substances are food materials rather than medicinal materials and cannot cause side effects on a human body due to excessive drinking.
Referring to fig. 1, when the polysaccharide is extracted from inonotus obliquus, a physical method can be used for extraction, and the physical method can be: the technical parameters of the high-voltage pulse electric field assisted extraction of the inonotus obliquus polysaccharide comprise: the electric field intensity is 30kV/cm, the pulse number is 6, and the solid-liquid ratio is 1: 25, pH value is 10; when ultrasonic-assisted extraction is carried out, the process parameters are as follows: ultrasonic treatment time is 70min, temperature is 80 ℃, frequency is 20kHz, and solid-to-liquid ratio is 1: 12; when the microwave is assisted, the microwave power is 88-96W, the polysaccharide in the inonotus obliquus is extracted by adopting an extraction method, the required reaction time is longer, the extraction of the polysaccharide is assisted by adopting a physical method, the time can be shortened to 30 minutes, the extraction rate is increased by 10%, the purity is increased by 5%, and the production efficiency is accelerated.
Example two: the inonotus obliquus can be deproteinized by adopting an enzymatic method, the dosage of the enzyme is 2%, the temperature is 60 ℃, the time is 4 hours, the pH value is 6, the enzymatic method is to utilize papain to carry out enzymolysis on protein, so that the protein is degraded into polypeptide with smaller relative molecular weight or more thorough amino acid, then alcohol precipitation is carried out, most of macromolecular polysaccharide is precipitated, most of the polypeptide and the amino acid with smaller relative molecular weight are remained in the solution, after several times of extraction, the removal rate of the protein is remarkably improved, the loss rate of the polysaccharide is remarkably reduced, and the deproteinization effect by the enzymatic method is better.
The points to be finally explained are: first, in the description of the present application, it should be noted that, unless otherwise specified and limited, the terms "mounted," "connected," and "connected" should be understood broadly, and may be a mechanical connection or an electrical connection, or a communication between two elements, and may be a direct connection, and "upper," "lower," "left," and "right" are only used to indicate a relative positional relationship, and when the absolute position of the object to be described is changed, the relative positional relationship may be changed;
secondly, the method comprises the following steps: in the drawings of the disclosed embodiments of the invention, only the structures related to the disclosed embodiments are referred to, other structures can refer to common designs, and the same embodiment and different embodiments of the invention can be combined with each other without conflict;
and finally: the above description is only for the purpose of illustrating the preferred embodiments of the present invention and is not to be construed as limiting the invention, and any modifications, equivalents, improvements and the like that are within the spirit and principle of the present invention are intended to be included in the scope of the present invention.
Claims (10)
1. The preparation method of the inonotus obliquus granule beverage is characterized by comprising the following steps:
s1, taking the inonotus obliquus, cleaning, drying, weighing, and crushing for later use;
s2, leaching the crushed inonotus obliquus to obtain an extracting solution, performing deproteinization and decoloration treatment on the extracting solution, preparing a solid after treatment, and weighing the solid;
s3, mixing the extract with a fixed weight with a diluent, a flavoring agent, an adhesive and the like, and concentrating into paste;
s4, drying the obtained paste, sieving and granulating.
2. The method for preparing inonotus obliquus granule beverage according to claim 1, characterized in that: the inonotus obliquus is extracted to obtain the polysaccharide inside the inonotus obliquus by adopting an extraction method, the material-liquid ratio of the inonotus obliquus in the extraction method is 1:33, the extraction temperature is 80 ℃, the extraction time is 2.2 hours, and the extraction frequency of the inonotus obliquus is set as two times.
3. The method for preparing inonotus obliquus granule beverage according to claim 2, characterized in that: the extraction of the polysaccharide in the inonotus obliquus can adopt an alcohol precipitation extraction method, the solid-liquid ratio is 1:15, the extraction time is 90 minutes, the extraction times of the inonotus obliquus are set to be two times, the crude drug concentration is 1.0g/ml, and the final ethanol concentration is 65%.
4. The method for preparing inonotus obliquus granule beverage according to claim 1, characterized in that: the crude polysaccharide extracted from the extracting solution is deproteinized by adopting a polyamide chromatographic adsorption column chromatography, the protein removal rate reaches 95.2%, and the polysaccharide retention rate is 89.7%.
5. The method for preparing inonotus obliquus granule beverage according to claim 1, characterized in that: and (3) decoloring the crude polysaccharide extracted from the extracting solution, removing pigments in the polysaccharide, and decoloring by using AB-8 resin, wherein the pH is 4.0, the temperature is 60 ℃, the decoloring rate of the crude polysaccharide is 87.38%, the retention rate of the polysaccharide is 89.24%, and the removal rate of protein is 77.11%.
6. The method for preparing inonotus obliquus granule beverage according to claim 1, characterized in that: the water content of the cleaned and dried inonotus obliquus is below 1.5%, and the inonotus obliquus is crushed and then screened by a 100-mesh screen.
7. The method for preparing inonotus obliquus granule beverage according to claim 1, characterized in that: the diluent is microcrystalline cellulose and xylitol, the proportion of the inonotus obliquus extract to the diluent is 100:10, the flavoring agent is a sweetening agent, the main substances are one or more of simple syrup, sucrose and modified starch carbohydrate, the proportion of the inonotus obliquus extract to the flavoring agent is 100:5, and the adhesive is absolute ethyl alcohol.
8. The method for preparing inonotus obliquus granule beverage according to claim 1, characterized in that: when the inonotus obliquus paste is prepared into granules, the drying temperature of the paste is 70 ℃, the paste is prepared into granules through a 16-mesh sieve, the granules are prepared into whole granules through a 12-mesh sieve, the granules are completely dried at the temperature of 60-80 ℃, and the drying temperature is gradually increased in the process.
9. The method for preparing inonotus obliquus granule beverage according to claim 1, characterized in that: black fungus, Chinese yam, bovine colostrum and sweet potatoes can be added into the inonotus obliquus granules, and the inonotus obliquus granules comprise the following components in percentage by weight: 25 parts of inonotus obliquus, 3 parts of Chinese yam, 2 parts of bovine colostrum and 5 parts of sweet potato.
10. The method for preparing inonotus obliquus granule beverage according to claim 2, characterized in that: when the polysaccharide is extracted from the inonotus obliquus, a physical method can be adopted for auxiliary extraction, and the physical method can be as follows: the technical parameters of the high-voltage pulse electric field assisted extraction of the inonotus obliquus polysaccharide comprise: the electric field intensity is 30kV/cm, the pulse number is 6, and the solid-liquid ratio is 1: 25, pH value is 10; when ultrasonic-assisted extraction is carried out, the process parameters are as follows: ultrasonic treatment time is 70min, temperature is 80 ℃, frequency is 20kHz, and solid-to-liquid ratio is 1: 12; when the microwave is used for assisting, the microwave power is 88-96W.
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115153070A (en) * | 2022-07-08 | 2022-10-11 | 吉林长白明珠森林食品有限公司 | Processing method and processing equipment of solid beverage powder for regulating blood sugar |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1565569A (en) * | 2003-07-03 | 2005-01-19 | 昆明市医学科学研究所 | Processing technique of Aconitum Carrnichaeli Debx |
| CN101392031A (en) * | 2008-11-10 | 2009-03-25 | 马宏达 | Extraction and separation method of inonotus obliquus polysaccharide |
| CN101791119A (en) * | 2010-02-03 | 2010-08-04 | 孟蒙 | Chaga nutrient composition |
| CN102603906A (en) * | 2011-12-30 | 2012-07-25 | 安徽丰原发酵技术工程研究有限公司 | Preparation method of inonotus obliquus polysaccharide aqueous solution |
| CN104045727A (en) * | 2014-06-25 | 2014-09-17 | 陈文灵 | Method for preparing inonotus obliquus (Fr.)Pilat crude polysaccharides by utilizing resin AB-8 with weak polarity |
| CN110150678A (en) * | 2019-05-09 | 2019-08-23 | 吉林农业大学 | Ginseng dietary fiber chewable tablets and preparation method thereof |
| CN110272506A (en) * | 2019-07-22 | 2019-09-24 | 湖北亿彤实业有限公司 | A kind of extracting method of Fuscoporia obliqua polysaccharide |
| CN110721205A (en) * | 2019-11-08 | 2020-01-24 | 吉林大学 | Preparation method and application of inonotus obliquus extract granules |
-
2021
- 2021-11-18 CN CN202111370800.9A patent/CN114009647A/en active Pending
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1565569A (en) * | 2003-07-03 | 2005-01-19 | 昆明市医学科学研究所 | Processing technique of Aconitum Carrnichaeli Debx |
| CN101392031A (en) * | 2008-11-10 | 2009-03-25 | 马宏达 | Extraction and separation method of inonotus obliquus polysaccharide |
| CN101791119A (en) * | 2010-02-03 | 2010-08-04 | 孟蒙 | Chaga nutrient composition |
| CN102603906A (en) * | 2011-12-30 | 2012-07-25 | 安徽丰原发酵技术工程研究有限公司 | Preparation method of inonotus obliquus polysaccharide aqueous solution |
| CN104045727A (en) * | 2014-06-25 | 2014-09-17 | 陈文灵 | Method for preparing inonotus obliquus (Fr.)Pilat crude polysaccharides by utilizing resin AB-8 with weak polarity |
| CN110150678A (en) * | 2019-05-09 | 2019-08-23 | 吉林农业大学 | Ginseng dietary fiber chewable tablets and preparation method thereof |
| CN110272506A (en) * | 2019-07-22 | 2019-09-24 | 湖北亿彤实业有限公司 | A kind of extracting method of Fuscoporia obliqua polysaccharide |
| CN110721205A (en) * | 2019-11-08 | 2020-01-24 | 吉林大学 | Preparation method and application of inonotus obliquus extract granules |
Non-Patent Citations (2)
| Title |
|---|
| 何树华: "有机化学实验", 华中科技大学出版社, pages: 271 * |
| 李欣欣: "桦褐孔菌多糖的分离纯化及其抗氧化活性测定", 食品工业科技, vol. 42, no. 11, pages 193 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115153070A (en) * | 2022-07-08 | 2022-10-11 | 吉林长白明珠森林食品有限公司 | Processing method and processing equipment of solid beverage powder for regulating blood sugar |
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