CN113996509B - Preparation process of metal coating bracket used under low pH - Google Patents
Preparation process of metal coating bracket used under low pH Download PDFInfo
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- CN113996509B CN113996509B CN202111651383.5A CN202111651383A CN113996509B CN 113996509 B CN113996509 B CN 113996509B CN 202111651383 A CN202111651383 A CN 202111651383A CN 113996509 B CN113996509 B CN 113996509B
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- rod
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- boron nitride
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- PZNSFCLAULLKQX-UHFFFAOYSA-N Boron nitride Chemical compound N#B PZNSFCLAULLKQX-UHFFFAOYSA-N 0.000 claims abstract description 62
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Images
Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D1/00—Processes for applying liquids or other fluent materials
- B05D1/02—Processes for applying liquids or other fluent materials performed by spraying
- B05D1/04—Processes for applying liquids or other fluent materials performed by spraying involving the use of an electrostatic field
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/02—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using physical phenomena
- A61L2/08—Radiation
- A61L2/10—Ultraviolet radiation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B13/00—Machines or plants for applying liquids or other fluent materials to surfaces of objects or other work by spraying, not covered by groups B05B1/00 - B05B11/00
- B05B13/02—Means for supporting work; Arrangement or mounting of spray heads; Adaptation or arrangement of means for feeding work
- B05B13/0221—Means for supporting work; Arrangement or mounting of spray heads; Adaptation or arrangement of means for feeding work characterised by the means for moving or conveying the objects or other work, e.g. conveyor belts
- B05B13/0228—Means for supporting work; Arrangement or mounting of spray heads; Adaptation or arrangement of means for feeding work characterised by the means for moving or conveying the objects or other work, e.g. conveyor belts the movement of the objects being rotative
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05B—SPRAYING APPARATUS; ATOMISING APPARATUS; NOZZLES
- B05B5/00—Electrostatic spraying apparatus; Spraying apparatus with means for charging the spray electrically; Apparatus for spraying liquids or other fluent materials by other electric means
- B05B5/08—Plant for applying liquids or other fluent materials to objects
- B05B5/082—Plant for applying liquids or other fluent materials to objects characterised by means for supporting, holding or conveying the objects
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D3/00—Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials
- B05D3/10—Pretreatment of surfaces to which liquids or other fluent materials are to be applied; After-treatment of applied coatings, e.g. intermediate treating of an applied coating preparatory to subsequent applications of liquids or other fluent materials by other chemical means
- B05D3/102—Pretreatment of metallic substrates
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D7/00—Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials
- B05D7/14—Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials to metal, e.g. car bodies
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B05—SPRAYING OR ATOMISING IN GENERAL; APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D—PROCESSES FOR APPLYING FLUENT MATERIALS TO SURFACES, IN GENERAL
- B05D7/00—Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials
- B05D7/24—Processes, other than flocking, specially adapted for applying liquids or other fluent materials to particular surfaces or for applying particular liquids or other fluent materials for applying particular liquids or other fluent materials
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Application Of Or Painting With Fluid Materials (AREA)
Abstract
The invention discloses a preparation process of a metal coating support for low pH, which comprises a base, wherein a limb driving mechanism is arranged at the upper end of the base, a turnover uniform smearing mechanism is arranged at the upper end of the limb driving mechanism, a bent tube high-voltage electrostatic generator nozzle is fixedly connected with the lower end surface of an installation plate, an adjusting valve is fixedly connected with the right end of the bent tube high-voltage electrostatic generator nozzle, a spring sealing switch rod is slidably connected with the middle end of the adjusting valve, a power extrusion block is fixedly connected with the lower end of the spring sealing switch rod, the sliding sleeve is driven to rotate while the sliding sleeve is driven to drive the slope extrusion block to rotate and move, the power extrusion block is extruded by the slope extrusion block to move upwards, the power extrusion block drives the spring sealing switch rod to move upwards, and the hollowed-out openings formed in the spring sealing switch rod are butted at the front and rear discharge openings of the regulating valve, and at the moment, the boron nitride coating is sprayed on the metal support from the inside of a nozzle of the bent tube high-voltage electrostatic generator.
Description
Technical Field
The invention relates to the field of stents, in particular to a preparation process of a metal coating stent used under low pH.
Background
The digestive tract stent is made of nickel-titanium memory alloy, the surface of one stent is also coated with a silicon rubber film, the mesh of the naked stent is closed, proliferative lesions cannot enter the inside of a tube cavity through the mesh and cannot cause restenosis, the digestive tract stent is in a cylindrical shape with one end or two ends in a horn shape, a cup shape, a spherical shape, a mushroom shape and the like, and the surface of the stent needs to be sprayed during preparation to increase the corrosion resistance in the stomach.
When current metallic coating support carries out the spraying, need artifical manual turn-over many times just can carry out even spraying usually, can't be automatic upset metallic coating support when the spraying, lead to the inhomogeneous condition of spraying thickness to take place to strengthen working strength, and current metallic coating support when the spraying, the shower nozzle is for lasting the spraying usually, can't carry out the automatic shutdown spraying when not having metallic coating support in the shower nozzle below, leads to more coating extravagant.
Disclosure of Invention
In order to solve the technical problem, the technical scheme solves the problems that when the existing metal coating support provided in the background technology is sprayed, manual turnover is usually needed for multiple times to carry out uniform spraying, the metal support cannot be automatically turned over during spraying, the spraying thickness is uneven, the working strength is increased, when the existing metal coating support is sprayed, a common spray head is used for continuous spraying, automatic spraying stop cannot be carried out when no metal support is below the spray head, and more coatings are wasted.
A preparation process of a metal coating stent used under low pH is characterized in that: the preparation process comprises the following steps:
step one, stripping pretreatment of boron nitride: adding boron nitride into an organic solvent, wherein the mass volume ratio of the boron nitride to the organic solvent is 1-2 g: 80-100 mL, performing ultrasonic treatment for more than 24 hours to form a concentration stripping boron nitride dispersion, performing centrifugal separation on the dispersion at the rotating speed of 5000-10000 rpm, washing, and drying the obtained solid;
step two, a preparation process of the metal coating bracket used under low pH: ultrasonically or mechanically dispersing the peeled boron nitride obtained in the step one in an organic coating;
the mass ratio of the stripping boron nitride to the main film forming substances in the organic coating in the step two is 1: 5-80;
step three, cleaning the bracket: sequentially placing the bracket into 75% ethanol solution, acetone and distilled water, sequentially ultrasonically oscillating and cleaning for 5-10min to remove residual oil stain and dust impurities on the surface of the bracket, then placing the bracket into chromic acid washing liquor to soak for 10-20min, then ultrasonically oscillating and thoroughly cleaning with distilled water for 20min, and then drying in a vacuum drying oven at 50 ℃ for 24 hours;
fourthly, spraying the boron nitride coating: one or more supports are serially connected and arranged on a controllable uniform-speed rotating device, the supports are grounded to be neutral in electricity through a lead, the prepared boron nitride coating is respectively injected into a 5ml-15ml injector, the boron nitride coating is conveyed to a coaxial nozzle by a micro sample injection pump, the boron nitride coating is rapidly sprayed out from the coaxial nozzle connected with a high-voltage electrostatic generator, the boron nitride coating is reduced into nano or micron-scale liquid drops, the surface of the boron nitride coating is extended into a conical Taylor cone under the action of electric field force due to the accumulation of a large amount of charges, a solvent is volatilized, the liquid drops are reduced and cracked into nano or micro-scale particles, the particles are deposited on the surface of the body part of the support, and a layer of uniform boron nitride coating is formed, and the electrostatic spraying process parameters are as follows: the rotating speed of the uniform-speed rotating receiving device is controlled to be 30-60r/min, the distance between the needle point and the uniform-speed rotating receiving device is 5-15cm, the injection rate of the external liquid is 0.5-1.5ml/h, the injection rate of the internal liquid is 0.1-0.5ml/h, the electric injection voltage is 8-15kv, and the spraying time is 30s-10 min; step five, drying and disinfecting the boron nitride coating: after the coating support is prepared, drying the coating support in a vacuum drying oven for 48 hours, and sterilizing the coating support by one of an ethylene oxide sterilization method, an ultraviolet irradiation sterilization method and a Co60 irradiation sterilization method;
step six, testing the ph of the coating: and after the operation of the steps is finished, taking out one of the brackets, soaking the bracket in a low-ph solution with the same ph value as the stomach for more than 48 hours, wherein the ph value of the solution is 1-0.6, taking out the bracket after 48 hours to detect the corrosion degree, and packaging the brackets in the same batch after reaching the standard.
Preferably, in the first step, the boron nitride is hexagonal boron nitride, in the first step, the organic solvent is selected from one of isopropanol, N-cyclohexyl-2-pyrrolidone, N-methyl pyrrolidone and dimethyl sulfoxide, and in the second step, the boron nitride is uniformly dispersed in an auxiliary agent or a solvent with low viscosity in advance through ultrasound or machinery; the mass volume ratio of the boron nitride to the auxiliary agent or the solvent is 1g: 10-2000 mL.
Preferably, the main film forming material is selected from resin and drying oil, the drying in the step one is vacuum freeze drying, the freezing temperature is-10 to-50 ℃, and the vacuum degree is less than or equal to 20 Pa.
Preferably, after the coating is finished, the thickness of the coating layer formed by drying is 50 μm or more.
Preferably, the inner diameter of the needle head inside the coaxial nozzle is 0.5-1mm, and the inner diameter of the needle head outside the coaxial nozzle is 0.8-1.8 mm.
Preferably, the boron nitride facilitates protection of the metal stent from corrosion at low pH. According to the preparation process of the metal coating support for the low pH, the metal coating support spraying device for the low pH comprises a base, wherein a limb driving mechanism is arranged at the upper end of the base, an overturning and uniform coating mechanism is arranged at the upper end of the limb driving mechanism, and an automatic saving switch spraying mechanism is arranged at the upper end of the overturning and uniform coating mechanism.
Preferably, the limb driving mechanism comprises a shaft rod, a multi-inclined-chute rotating column, a spring poking rod, a sliding block, a positioning sliding sleeve, a torsional spring pedal and a supporting bending rod, the lower end of the shaft rod is fixedly connected with the multi-inclined-chute rotating column, one end of the multi-inclined-chute rotating column is slidably connected with the spring poking rod, the outer surface of the front end of the spring poking rod is slidably connected with the sliding block, the outer surface of the sliding block is slidably connected with the positioning sliding sleeve, the lower end of the positioning sliding sleeve is fixedly connected to the upper end face of the base, the middle end of the sliding block is rotatably connected with the torsional spring pedal, the right end of the torsional spring pedal is rotatably connected with the supporting bending rod, and the left end of the supporting bending rod is rotatably connected to the outer surface of the lower end of the positioning sliding sleeve.
Preferably, the mechanism is evenly paintd in upset includes triangle slope spout dish, spacing set-square, two pole slide bars, drive sliding sleeve, slope extrusion piece, fixed square pole, the fixed square pole of location sliding sleeve upper end fixedly connected with, fixed square pole upper end fixedly connected with triangle slope spout dish, triangle slope spout dish lower extreme is provided with spacing set-square, the equal fixed connection of spacing set-square one end is in fixed square pole surface, the even sliding connection of two pole slide bars one end is in triangle slope spout dish terminal surface diameter down, the even rotation of two pole slide bars middle-end is connected in drive sliding sleeve diameter, the even fixedly connected with slope extrusion piece in slope extrusion piece upper end.
Preferably, one end of each double-rod sliding rod is fixedly connected with a sliding spring sleeve rod, the middle end of each sliding spring sleeve rod is fixedly connected with a spring cylinder, the inner part of the middle end of the spring cylinder is connected with a rubber positioning rod in a sliding way, the front end and the rear end of the sliding spring loop bar are both fixedly connected with round head bars, the left end of the round head rod is connected with a bidirectional slope ring in a sliding way, the left end of the round head rod is provided with an inserting cylinder, one end of the inserting cylinder is fixedly connected with the sliding spring sleeve rod, the left end and the right end of the inserting cylinder are connected with the slope spring rod in a sliding way, the middle end of the sliding spring loop bar is rotationally connected with an inclined chute turntable, the arc plate is evenly and slidably connected in the diameter of the inclined chute turntable, the arc plate right-hand member sliding connection has short spout, the equal fixed connection in slip spring loop bar right-hand member of short spout right-hand member, spout carousel right-hand member fixedly connected with adjusts the swivel cap to one side.
Preferably, the automatic saving switch spraying mechanism comprises a bent pipe high-voltage electrostatic generator nozzle, a regulating valve, a spring sealing switch rod, a power extrusion block and a mounting plate, wherein the mounting plate is fixedly connected with the outer side wall of one end of a fixed square rod, the bent pipe high-voltage electrostatic generator nozzle is fixedly connected with the lower end face of the mounting plate, the regulating valve is fixedly connected with the right end of the bent pipe high-voltage electrostatic generator nozzle, the spring sealing switch rod is slidably connected with the middle end of the regulating valve, and the power extrusion block is fixedly connected with the lower end of the spring sealing switch rod.
Compared with the prior art, the invention has the beneficial effects that:
(1) the shaft lever rotates and simultaneously drives the driving sliding sleeve to rotate, the driving sliding sleeve drives the double-rod sliding rod to slide at the bottom of the triangular slope sliding groove disc, when the double-rod sliding rod slides to the triangular slope sliding groove disc and is provided with a triangular sliding groove, one end of the double-rod sliding rod slides in the triangular sliding groove and slides at the edge of the lower end of the limit triangular plate, the driving sliding sleeve continuously rotates at the moment, one end of the double-rod sliding in the triangular sliding groove arranged on the triangular slope sliding groove disc moves to the groove above the triangular sliding groove arranged on the triangular slope sliding groove disc to rotate, one end of the double-rod sliding at the edge of the lower end of the limit triangular plate rotates and contacts at the edge of the lower end of the triangular slope sliding groove disc at the moment, and simultaneously drives the metal support to turn over, so that the aim of automatically turning over the metal support is achieved, and the complexity of secondary spraying is avoided;
(2) after the disinfection is finished, the metal support is sleeved outside the rubber positioning rod, the sliding spring sleeve rod is pushed to move leftwards, the round head rod is driven to be in butt joint with the insertion cylinder, the round head rod extrudes the slope spring rod to move towards two sides at the moment, the round head rod moves to the back of the slope spring rod and is in contact with and hooked with the back of the slope spring rod, the purpose of quick fixation is achieved, and the trouble of fixing by using a complex clamping mechanism is avoided;
(3) the rotary adjusting rotating cap drives the inclined chute rotating disc to rotate, the inclined chute rotating disc drives the arc plate to move towards the middle in the short chute, the diameter between the arc plate and the arc plate is adjusted, the situation that the metal support is shaken is avoided, and meanwhile, the situation that the metal support is damaged in the clamping process by using a traditional clamping mechanism is avoided;
(4) after the metal support is installed, the torsional spring pedal is treaded by feet to drive the spring poke rod to slide downwards at the chute arranged in the multi-inclined chute rotating column, the multi-inclined chute rotating column is driven to rotate in the sliding process, when the torsional spring pedal is treaded to finish, the torsional spring arranged on the torsional spring pedal drives the torsional spring pedal to move upwards by taking the support bending rod as a support point and drives the spring poke rod to move downwards, the chute arranged on the multi-inclined chute rotating column extrudes the poke rod arranged on the spring poke rod to move forwards, when the spring poke rod moves to the upper end of the multi-inclined chute rotating column, the spring poke rod moves into the chute arranged on the next multi-inclined chute rotating column, so that the shaft rod is driven to rotate by the multi-inclined chute rotating column, the rotating speed is adjusted by limbs, the purpose of satisfying spraying thickness is achieved, the situation that the electric drive rotation is used is avoided, and the surface without spraying can not be controlled in time, resulting in the need for secondary spraying.
Drawings
FIG. 1 is a schematic perspective view of a metallic coating stent coating apparatus according to the present invention;
FIG. 2 is a schematic perspective view of the shaft lever and multi-inclined-chute rotating column of the present invention;
FIG. 3 is a schematic perspective view of the spring moving rod and the sliding block according to the present invention;
FIG. 4 is a schematic perspective view of a dual-rod sliding rod in a driving sliding sleeve according to the present invention;
FIG. 5 is a schematic perspective view of the sliding spring rod and spring cartridge of the present invention;
FIG. 6 is a schematic perspective view of the arc plate and short chute of the present invention;
FIG. 7 is a schematic perspective view of the round-headed stem and the bidirectional ramp ring of the present invention;
FIG. 8 is a perspective view of the insertion tube and the spring rod of the present invention;
FIG. 9 is a schematic perspective view of the triangular slope chute disc and the limiting triangular plate of the present invention;
fig. 10 is a schematic perspective view of the automatic saving switch spraying mechanism of the present invention.
The reference numbers in the figures are:
1. a base; 2. a limb drive mechanism; 201. a shaft lever; 202. a multi-inclined chute rotating column; 203. a spring poke rod; 204. a slider; 205. positioning the sliding sleeve; 206. a torsion spring foot pedal; 207. supporting the bent rod; 3. turning over the uniform smearing mechanism; 301. a triangular slope chute disc; 302. a limiting triangle; 303. a double-rod slide rod; 304. driving the sliding sleeve; 305. a slope extrusion block; 306. fixing the square rod; 307. a sliding spring loop bar; 308. a spring case; 309. a rubber positioning rod; 310. a round head bar; 311. a bidirectional slope ring; 312. inserting a cylinder; 313. a ramp spring lever; 314. a diagonal chute turntable; 315. a circular arc plate; 316. a short chute; 317. adjusting the rotating cap; 4. the spraying mechanism is automatically switched on and off; 401. a bent tube high-voltage electrostatic generator nozzle; 402. adjusting a valve; 403. the spring seals the switch rod; 404. a power extrusion block; 405. and (7) mounting the plate.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
The first embodiment is as follows: a preparation process of a metal coating bracket used under low pH comprises the following steps:
step one, stripping pretreatment of boron nitride: adding boron nitride into an organic solvent, wherein the mass volume ratio of the boron nitride to the organic solvent is 1-2 g: 80-100 mL, performing ultrasonic treatment for more than 24 hours to form a concentration stripping boron nitride dispersion, performing centrifugal separation on the dispersion at the rotating speed of 5000-10000 rpm, washing, and drying the obtained solid;
step two, a preparation process of the metal coating bracket used under low pH: ultrasonically or mechanically dispersing the peeled boron nitride obtained in the step one in an organic coating; the mass ratio of the stripping boron nitride to the main film forming substances in the organic coating in the step two is 1: 5-80;
step three, cleaning the bracket: sequentially placing the bracket into 75% ethanol solution, acetone and distilled water, sequentially ultrasonically oscillating and cleaning for 5-10min to remove residual oil stain and dust impurities on the surface of the bracket, then placing the bracket into chromic acid washing liquor to soak for 10-20min, then ultrasonically oscillating and thoroughly cleaning with distilled water for 20min, and then drying in a vacuum drying oven at 50 ℃ for 24 hours;
fourthly, spraying the boron nitride coating: one or more supports are serially connected and arranged on a controllable uniform-speed rotating device, the supports are grounded to be neutral in electricity through a lead, the prepared boron nitride coating is respectively injected into a 5ml-15ml injector, the boron nitride coating is conveyed to a coaxial nozzle by a micro sample injection pump, the boron nitride coating is rapidly sprayed out from the coaxial nozzle connected with a high-voltage electrostatic generator, the boron nitride coating is reduced into nano or micron-scale liquid drops, the surface of the boron nitride coating is extended into a conical Taylor cone under the action of electric field force due to the accumulation of a large amount of charges, a solvent is volatilized, the liquid drops are reduced and cracked into nano or micro-scale particles, the particles are deposited on the surface of the body part of the support, and a layer of uniform boron nitride coating is formed, and the electrostatic spraying process parameters are as follows: the rotating speed of the uniform-speed rotating receiving device is controlled to be 30-60r/min, the distance between the needle point and the uniform-speed rotating receiving device is 5-15cm, the injection rate of the external liquid is 0.5-1.5ml/h, the injection rate of the internal liquid is 0.1-0.5ml/h, the electric injection voltage is 8-15kv, and the spraying time is 30s-10 min;
step five, drying and disinfecting the boron nitride coating: and after the coating support is prepared, drying the coating support in a vacuum drying oven for 48 hours, and sterilizing by one of an ethylene oxide sterilization method, an ultraviolet irradiation sterilization method and a Co60 irradiation sterilization method.
Sixthly, testing the boron nitride coating ph: and after the operation of the steps is finished, taking out one of the brackets, soaking the bracket in a low-ph solution with the same ph value as the stomach for more than 48 hours, wherein the ph value of the solution is 1-0.6, taking out the bracket after 48 hours to detect the corrosion degree, and packaging the brackets in the same batch after reaching the standard.
Preferably, the method comprises the following steps: in the first step, the boron nitride is hexagonal boron nitride, in the first step, the organic solvent is selected from one of isopropanol, N-cyclohexyl-2-pyrrolidone, N-methyl pyrrolidone and dimethyl sulfoxide, and in the second step, the boron nitride is uniformly dispersed in an auxiliary agent or a solvent with low viscosity in advance through ultrasound or machinery; the mass volume ratio of the boron nitride to the auxiliary agent or the solvent is 1g: 10-2000 mL.
Preferably, the method comprises the following steps: the main film forming matter is selected from resin and drying oil, the drying in the first step is vacuum freeze drying, the freezing temperature is-10 to-50 ℃, and the vacuum degree is less than or equal to 20 Pa.
Preferably, the method comprises the following steps: after the coating is finished, the thickness of the coating formed by drying is more than 50 mu m.
Preferably, the method comprises the following steps: the inner diameter of the needle head inside the coaxial nozzle is 0.5-1mm, and the inner diameter of the needle head outside the coaxial nozzle is 0.8-1.8 mm.
Preferably, the method comprises the following steps: boron nitride facilitates protection of the metal stent from corrosion at low ph.
Example two: referring to fig. 2 and fig. 3, as the above-mentioned preparation process of a metal-coated stent for use under low pH, a spraying device of a metal-coated stent for use under low pH is proposed, which comprises a base 1, a limb driving mechanism 2 is arranged at the upper end of the base 1, an overturning uniform coating mechanism 3 is arranged at the upper end of the limb driving mechanism 2, an automatic saving switch spraying mechanism 4 is arranged at the upper end of the overturning uniform coating mechanism 3, the limb driving mechanism 2 comprises a shaft rod 201, a multi-inclined chute rotating column 202, a spring poking rod 203, a sliding block 204, a positioning sliding sleeve 205, a torsion spring pedal 206, a supporting bending rod 207, the multi-inclined chute rotating column 202 is fixedly connected at the lower end of the shaft rod 201, a spring poking rod 203 is slidably connected at one end of the multi-inclined chute rotating column 202, the sliding block 204 is slidably connected at the outer surface of the front end of the spring poking rod 203, the sliding sleeve 205 is slidably connected at the outer surface of the sliding block 204, the lower end of the positioning sliding sleeve 205 is fixedly connected at the upper end of the base 1, the middle end of the sliding block 204 is rotatably connected with a torsion spring pedal 206, the right end of the torsion spring pedal 206 is rotatably connected with a support bending rod 207, and the left end of the support bending rod 207 is rotatably connected with the outer surface of the lower end of the positioning sliding sleeve 205.
The working principle is as follows: after the metal support is installed, the torsional spring pedal 206 is treaded by feet to drive the spring poking rod 203 to slide downwards at the chute arranged in the multi-inclined chute rotating column 202, the multi-inclined chute rotating column 202 is driven to rotate in the sliding process, when the torsional spring pedal 206 is treaded, the torsional spring arranged on the torsional spring pedal 206 drives the torsional spring pedal 206 to move upwards through the support bending rod 207 as a support point and drives the spring poking rod 203 to move downwards, at the moment, the chute arranged on the multi-inclined chute rotating column 202 extrudes the poking rod arranged on the spring poking rod 203 to move forwards, when the spring poking rod 203 moves to the upper end of the multi-inclined chute rotating column 202, the spring poking rod 203 moves into the chute arranged on the next multi-inclined chute rotating column 202, so that the multi-inclined chute rotating column 202 drives the spring poking rod 201 to rotate, the rotating speed is adjusted through limbs, and the purpose of satisfactory spraying thickness is achieved, the problem that the secondary spraying is complex due to the fact that the surface which is not sprayed cannot be timely controlled by using electric drive rotation is avoided.
Example three: referring to fig. 1 and 5 and fig. 6 and fig. 7 and fig. 8 and 9, the turnover uniform coating mechanism 3 includes a triangular slope chute disc 301, a limit triangle 302, a two-bar slide bar 303, a driving slide sleeve 304, a slope extrusion block 305, a fixed square bar 306 fixedly connected to the upper end of the positioning slide sleeve 205, a triangular slope chute disc 301 fixedly connected to the upper end of the fixed square bar 306, a limit triangle 302 arranged at the lower end of the triangular slope chute disc 301, one end of the limit triangle 302 fixedly connected to the outer surface of the fixed square bar 306, one end of the two-bar slide bar 303 uniformly slidably connected to the diameter of the lower end surface of the triangular slope chute disc 301, a middle end of the two-bar slide bar 303 uniformly rotatably connected to the diameter of the driving slide sleeve 304, a slope extrusion block 305 uniformly fixedly connected to the upper end of the slope extrusion block 305, a sliding spring sleeve 307 fixedly connected to one end of the two-bar slide bar 303, a spring sleeve 308 fixedly connected to the middle end of the sliding spring sleeve 307, spring cylinder 308 middle-end inside sliding connection has rubber location stick 309, the equal fixedly connected with button head pole 310 in both ends around the slip spring loop bar 307, button head pole 310 left end sliding connection has two-way slope circle 311, button head pole 310 left end is provided with inserts a section of thick bamboo 312, the equal fixed connection in slip spring loop bar 307 in 312 one end of inserting a section of thick bamboo, insert the equal sliding connection in both ends and have slope spring pole 313 about a section of thick bamboo 312, slip spring loop bar 307 middle-end rotates and is connected with oblique spout carousel 314, the even sliding connection of arc board 315 is in oblique spout carousel 314 diameter, arc board 315 right-hand member sliding connection has short spout 316, the equal fixed connection in slip spring loop bar 307 right-hand member face of short spout 316 right-hand member, oblique spout carousel 314 right-hand member fixedly connected with adjusts swivel cap 317.
The working principle is as follows: after the disinfection is finished, the metal bracket is sleeved outside the rubber positioning rod 309, the sliding spring sleeve rod 307 is pushed to move leftwards, the round head rod 310 is driven to be in butt joint with the inserting cylinder 312, the round head rod 310 extrudes the slope spring rod 313 to move towards two sides, the round head rod 310 moves to the back of the slope spring rod 313 and is in contact with the back of the slope spring rod 313 to hook, the purpose of quick fixation is achieved, the trouble of fixing by using a complex clamping mechanism is avoided, after the fixation is finished, the rotating cap 317 is rotationally adjusted to drive the inclined chute turntable 314 to rotate, the inclined chute turntable 314 drives the arc plate 315 to move towards the middle in the short chute 316, the diameter between the arc plate 315 and the arc plate 315 is adjusted, the situation that the metal bracket shakes is avoided, meanwhile, the situation that the metal bracket is damaged in the clamping process by using the traditional clamping mechanism is avoided, after the clamping is finished, the shaft lever 201 rotates and simultaneously drives the driving sliding sleeve 304 to rotate, the driving sliding sleeve 304 drives the double-rod sliding rod 303 to slide at the bottom of the triangular slope sliding groove disc 301, when the double-rod slide bar 303 slides to the position where the triangular chute disc 301 is provided with the triangular chute, one end of the double-rod slide bar 303 slides in the triangular chute and the other end slides at the lower end edge of the limit triangular plate 302, at the moment, the drive slide sleeve 304 continuously rotates, one end of the double-rod slide bar 303 sliding in the triangular chute arranged on the triangular chute disc 301 moves to the upper side groove of the triangular chute arranged on the triangular chute disc 301 for rotation, at the moment, one end of the double-rod slide bar 303 sliding at the lower end edge of the limit triangular plate 302 rotatably contacts at the lower end edge of the triangular chute disc 301, meanwhile, the metal support is driven to overturn, the purpose of automatically overturning the metal support is achieved, and the trouble of secondary spraying after manual overturning is avoided.
Example four: referring to fig. 10, the automatic saving switch spraying mechanism 4 includes a curved tube high voltage electrostatic generator nozzle 401, a regulating valve 402, a spring seal switch rod 403, a power extrusion block 404, and a mounting plate 405, the outer side wall of one end of the fixed square rod 306 is fixedly connected with the mounting plate 405, the lower end face of the mounting plate 405 is fixedly connected with the curved tube high voltage electrostatic generator nozzle 401, the right end of the curved tube high voltage electrostatic generator nozzle 401 is fixedly connected with the regulating valve 402, the middle end of the regulating valve 402 is slidably connected with the spring seal switch rod 403, and the lower end of the spring seal switch rod 403 is fixedly connected with the power extrusion block 404.
The working principle is as follows: the sliding sleeve 304 is driven to rotate while the sliding sleeve 304 is driven to drive the slope extrusion block 305 to rotate and move, the slope extrusion block 305 extrudes the power extrusion block 404 to move upwards, the power extrusion block 404 drives the spring seal switch rod 403 to move upwards, hollow openings formed in the spring seal switch rod 403 are butted at front and rear discharge openings of the regulating valve 402, at the moment, boron nitride coating is sprayed on a metal support from the bent pipe high-voltage electrostatic generator nozzle 401, when the slope extrusion block 305 finishes extruding the power extrusion block 404, the inlet and the outlet of the regulating valve 402 are plugged by the solid core seal arranged at the upper end of the spring seal switch rod 403, so that the bent pipe high-voltage electrostatic generator nozzle 401 stops spraying the boron nitride coating, the aim of automatically stopping spraying when no metal support passes through the spray head is achieved, continuous spraying is avoided, and waste of the boron nitride coating is caused.
Example five: referring to fig. 1 to 10, a spraying device for a metal coating stent under low pH comprises a base 1, a limb driving mechanism 2 is arranged at the upper end of the base 1, a turning uniform coating mechanism 3 is arranged at the upper end of the limb driving mechanism 2, an automatic saving switch spraying mechanism 4 is arranged at the upper end of the turning uniform coating mechanism 3, the limb driving mechanism 2 comprises a shaft rod 201, a multi-inclined chute rotating column 202, a spring poking rod 203, a sliding block 204, a positioning sliding sleeve 205, a torsional spring pedal 206 and a support bending rod 207, the lower end of the shaft rod 201 is fixedly connected with the multi-inclined chute rotating column 202, one end of the multi-inclined chute rotating column 202 is slidably connected with the spring poking rod 203, the outer surface of the front end of the spring poking rod 203 is slidably connected with the sliding block 204, the outer surface of the sliding block 204 is slidably connected with the positioning sliding sleeve 205, the lower end of the positioning sliding sleeve 205 is fixedly connected with the upper end surface of the base 1, the middle end of the sliding block 204 is rotatably connected with the torsional spring pedal 206, the right end of the torsional spring pedal 206 is rotatably connected with a supporting bending rod 207, the left end of the supporting bending rod 207 is rotatably connected with the outer surface of the lower end of the positioning sliding sleeve 205, the turnover uniform smearing mechanism 3 comprises a triangular slope sliding groove disc 301, a limiting triangular plate 302, a double-rod sliding rod 303, a driving sliding sleeve 304, a slope extrusion block 305 and a fixed square rod 306, the upper end of the positioning sliding sleeve 205 is fixedly connected with the fixed square rod 306, the upper end of the fixed square rod 306 is fixedly connected with the triangular slope sliding groove disc 301, the lower end of the triangular slope sliding groove disc 301 is provided with the limiting triangular plate 302, one end of the limiting triangular plate 302 is fixedly connected with the outer surface of the fixed square rod 306, one end of the double-rod sliding rod 303 is uniformly and slidably connected in the diameter of the lower end face of the triangular slope sliding groove disc 301, the middle end of the double-rod sliding rod 303 is uniformly and rotatably connected in the diameter of the driving sliding sleeve 304, the upper end of the slope extrusion block 305 is uniformly and fixedly connected with the slope extrusion block 305, one end of the double-rod sliding rod 303 is fixedly connected with a sliding spring sleeve 307, the middle end of a sliding spring sleeve rod 307 is fixedly connected with a spring cylinder 308, the inner part of the middle end of the spring cylinder 308 is slidably connected with a rubber positioning rod 309, round-head rods 310 are fixedly connected with the front end and the rear end of the sliding spring sleeve rod 307 respectively, the left end of the round-head rod 310 is slidably connected with a bidirectional slope ring 311, the left end of the round-head rod 310 is provided with an inserting cylinder 312, one end of the inserting cylinder 312 is fixedly connected with the sliding spring sleeve rod 307, the left end and the right end of the inserting cylinder 312 are slidably connected with slope spring rods 313, the middle end of the sliding spring sleeve rod 307 is rotatably connected with an inclined chute turntable 314, an arc plate 315 is uniformly and slidably connected in the diameter of the inclined chute turntable 314, the right end of the arc plate 315 is slidably connected with a short chute 316, the right end of the short chute 316 is fixedly connected with the right end surface of the sliding spring sleeve rod 307, the right end of the inclined chute turntable 314 is fixedly connected with an adjusting rotating cap 317, and the automatic saving switch spraying mechanism 4 comprises a bent tube high-voltage static nozzle 401, The adjustable pressure square rod comprises a regulating valve 402, a spring sealing switch rod 403, a power extrusion block 404 and a mounting plate 405, wherein the outer side wall of one end of a fixed square rod 306 is fixedly connected with the mounting plate 405, the lower end face of the mounting plate 405 is fixedly connected with a bent tube high-voltage electrostatic generator nozzle 401, the right end of the bent tube high-voltage electrostatic generator nozzle 401 is fixedly connected with a regulating valve 402, the middle end of the regulating valve 402 is slidably connected with the spring sealing switch rod 403, and the lower end of the spring sealing switch rod 403 is fixedly connected with the power extrusion block 404.
The working principle is as follows: after the disinfection, the metal support is sleeved outside the rubber positioning rod 309, the sliding spring sleeve rod 307 is pushed to move leftwards, the round head rod 310 is driven to be in butt joint with the inserting cylinder 312, the round head rod 310 extrudes the slope spring rod 313 to move towards two sides, the round head rod 310 moves to the back of the slope spring rod 313 and is hooked with the back of the slope spring rod 313 in a contact mode, the purpose of quick fixation is achieved, and the trouble of fixing by using a complex clamping mechanism is avoided.
After fixed the completion, it is rotatory to carry out rotation regulation and to change cap 317 and drive oblique spout carousel 314, and oblique spout carousel 314 drives circular arc board 315 and moves to the centre in short spout 316 department, adjusts the diameter between circular arc board 315 and the circular arc board 315, avoids the condition emergence that metal support took place to rock, has avoided using traditional fixture to make the condition emergence that metal support damaged in clamping process simultaneously.
After the adjustment is completed, the shaft 201 rotates and simultaneously drives the driving sliding sleeve 304 to rotate, the driving sliding sleeve 304 drives the double-rod sliding rod 303 to slide at the bottom of the triangular slope sliding groove disc 301, when the double-rod slide bar 303 slides to the position where the triangular chute disc 301 is provided with the triangular chute, one end of the double-rod slide bar 303 slides in the triangular chute and the other end slides at the lower end edge of the limit triangular plate 302, at the moment, the drive slide sleeve 304 continuously rotates, one end of the double-rod slide bar 303 sliding in the triangular chute arranged on the triangular chute disc 301 moves to the upper side groove of the triangular chute arranged on the triangular chute disc 301 for rotation, at the moment, one end of the double-rod slide bar 303 sliding at the lower end edge of the limit triangular plate 302 rotatably contacts at the lower end edge of the triangular chute disc 301, meanwhile, the metal support is driven to overturn, the purpose of automatically overturning the metal support is achieved, and the trouble of secondary spraying after manual overturning is avoided.
The sliding sleeve 304 is driven to rotate while the sliding sleeve 304 is driven to drive the slope extrusion block 305 to rotate and move, the slope extrusion block 305 extrudes the power extrusion block 404 to move upwards, the power extrusion block 404 drives the spring seal switch rod 403 to move upwards, hollow openings formed in the spring seal switch rod 403 are butted at front and rear discharge openings of the regulating valve 402, at the moment, boron nitride coating is sprayed on a metal support from the bent pipe high-voltage electrostatic generator nozzle 401, when the slope extrusion block 305 finishes extruding the power extrusion block 404, the inlet and the outlet of the regulating valve 402 are plugged by the solid core seal arranged at the upper end of the spring seal switch rod 403, so that the bent pipe high-voltage electrostatic generator nozzle 401 stops spraying the boron nitride coating, the aim of automatically stopping spraying when no metal support passes through the spray head is achieved, continuous spraying is avoided, and waste of the boron nitride coating is caused.
Although embodiments of the present invention have been shown and described, it will be appreciated by those skilled in the art that changes, modifications, substitutions and alterations can be made in these embodiments without departing from the principles and spirit of the invention, the scope of which is defined in the appended claims and their equivalents.
Claims (5)
1. A preparation process of a metal coating stent used under low pH is characterized in that: the preparation process comprises the following steps: step one, stripping pretreatment of boron nitride: adding boron nitride into an organic solvent, wherein the mass volume ratio of the boron nitride to the organic solvent is 1-2 g: 80-100 mL, performing ultrasonic treatment for more than 24 hours to form a boron nitride dispersion with stripped concentration, performing centrifugal separation on the dispersion at the rotating speed of 5000-10000 rpm, washing, and drying the obtained solid; step two, ultrasonically or mechanically dispersing the stripped boron nitride obtained in the step one in an organic coating; the mass ratio of the stripping boron nitride to the main film forming substances in the organic coating in the step two is 1: 5-80; step three, cleaning the bracket: sequentially placing the bracket into 75% ethanol solution, acetone and distilled water, sequentially ultrasonically oscillating and cleaning for 5-10min to remove residual oil stain and dust impurities on the surface of the bracket, then placing the bracket into chromic acid washing liquor to soak for 10-20min, then ultrasonically oscillating and thoroughly cleaning with distilled water for 20min, and then drying in a vacuum drying oven at 50 ℃ for 24 hours; fourthly, spraying the boron nitride coating: one or more supports are serially connected and arranged on a controllable uniform-speed rotating device, the supports are grounded to be neutral electrically through a lead, the prepared boron nitride coating is respectively injected into a 5mL-15mL injector, the boron nitride coating is conveyed to a coaxial nozzle by a micro sample injection pump, the boron nitride coating is rapidly sprayed out from the coaxial nozzle connected with a high-voltage electrostatic generator, the boron nitride coating is reduced into nano or micron-scale liquid drops, the surface of the boron nitride coating is extended into a conical Taylor cone under the action of electric field force due to the accumulation of a large amount of charges, a solvent is volatilized, the liquid drops are reduced and cracked into nano and micron-scale particles, the particles are deposited on the surface of the body part of the support, and a layer of uniform boron nitride coating is formed, and the electrostatic spraying process parameters are as follows: the rotating speed of the uniform-speed rotating receiving device is controlled to be 30-60r/min, the distance between the needle tip and the uniform-speed rotating receiving device is 5-15cm, the injection rate of the external liquid is 0.5-1.5mL/h, the injection rate of the internal liquid is 0.1-0.5mL/h, the electric injection voltage is 8-15kv, and the spraying time is 30s-10 min; step five, drying and disinfecting the boron nitride coating: after the coating support is prepared, drying the coating support in a vacuum drying oven for 48 hours, and sterilizing the coating support by one of an ethylene oxide sterilization method, an ultraviolet irradiation sterilization method and a Co60 irradiation sterilization method; step six, testing the pH value of the coating: after the operation of the steps is finished, taking out one of the brackets, soaking the bracket in a low pH value solution which is the same as that of the stomach for more than 48 hours, wherein the pH value of the solution is 1-0.6, taking out the bracket after 48 hours to detect the corrosion degree, and packaging the brackets in the same batch after reaching the standard;
step four, placing the disinfected metal bracket on a metal coating bracket spraying device for spraying; the spraying device for the metal coating support comprises a base (1), wherein a limb driving mechanism (2) is arranged at the upper end of the base (1), a turnover uniform smearing mechanism (3) is arranged at the upper end of the limb driving mechanism (2), and an automatic saving switch spraying mechanism (4) is arranged at the upper end of the turnover uniform smearing mechanism (3);
the limb driving mechanism (2) comprises a shaft lever (201), a multi-inclined chute rotating column (202), a spring poke rod (203), a sliding block (204), a positioning sliding sleeve (205), a torsion spring pedal (206) and a supporting bending rod (207), the lower end of the shaft lever (201) is fixedly connected with a multi-inclined chute rotating column (202), one end of the multi-inclined chute rotating column (202) is connected with a spring poke rod (203) in a sliding way, the outer surface of the front end of the spring poke rod (203) is connected with a slide block (204) in a sliding way, the outer surface of the sliding block (204) is connected with a positioning sliding sleeve (205) in a sliding way, the lower end of the positioning sliding sleeve (205) is fixedly connected with the upper end surface of the base (1), the middle end of the sliding block (204) is rotationally connected with a torsional spring pedal (206), the right end of the torsional spring pedal (206) is rotationally connected with a supporting bending rod (207), the left end of the support bending rod (207) is rotatably connected with the outer surface of the lower end of the positioning sliding sleeve (205);
the turnover uniform smearing mechanism (3) comprises a triangular slope sliding groove disc (301), a limiting triangular plate (302), a double-rod sliding rod (303), a driving sliding sleeve (304), a slope extrusion block (305) and a fixed square rod (306), the upper end of the positioning sliding sleeve (205) is fixedly connected with a fixed square rod (306), the upper end of the fixed square rod (306) is fixedly connected with a triangular slope sliding groove disc (301), the lower end of the triangular slope chute disc (301) is provided with a limit triangular plate (302), one end of each limit triangular plate (302) is fixedly connected with the outer surface of the fixed square rod (306), one end of the double-rod sliding rod (303) is evenly and slidably connected in the diameter of the lower end face of the triangular slope chute disc (301), the middle end of the double-rod sliding rod (303) is uniformly and rotatably connected in the diameter of the driving sliding sleeve (304), the upper end of the driving sliding sleeve (304) is uniformly and fixedly connected with a slope extrusion block (305);
one end of each double-rod sliding rod (303) is fixedly connected with a sliding spring sleeve rod (307), the middle end of each sliding spring sleeve rod (307) is fixedly connected with a spring barrel (308), the inner part of the middle end of each spring barrel (308) is connected with a rubber positioning rod (309) in a sliding manner, the front end and the rear end of each sliding spring sleeve rod (307) are fixedly connected with round-head rods (310), the left end of each round-head rod (310) is connected with a bidirectional slope ring (311) in a sliding manner, the left end of each round-head rod (310) is provided with an inserting barrel (312), one end of each inserting barrel (312) is fixedly connected with the corresponding sliding spring sleeve rod (307), the left end and the right end of each inserting barrel (312) are connected with slope spring rods (313) in a sliding manner, the middle end of each sliding spring sleeve rod (307) is rotatably connected with an inclined chute turntable (314), each arc plate (315) is uniformly slidably connected in the diameter of the inclined chute turntable (314), and the right end of each arc plate (315) is connected with a short chute (316) in a sliding manner, the right ends of the short sliding chutes (316) are fixedly connected to the right end surface of the sliding spring sleeve rod (307), and the right end of the inclined sliding chute turntable (314) is fixedly connected with an adjusting rotating cap (317);
automatic sparingly switch spraying mechanism (4) are including crooked tub of high-voltage static generator nozzle (401), governing valve (402), spring seal switch lever (403), power extrusion piece (404), mounting panel (405), fixed square bar (306) one end lateral wall fixedly connected with mounting panel (405), terminal surface fixedly connected with crooked tub of high-voltage static generator nozzle (401) under mounting panel (405), crooked tub of high-voltage static generator nozzle (401) right-hand member fixedly connected with governing valve (402), governing valve (402) middle-end sliding connection has spring seal switch lever (403), spring seal switch lever (403) lower extreme fixedly connected with power extrusion piece (404).
2. The process of claim 1 for the preparation of a metal coated stent at low pH, wherein: in the second step, the boron nitride is uniformly dispersed in an auxiliary agent or solvent with low viscosity in advance through ultrasound or machinery, and the mass-volume ratio of the boron nitride to the auxiliary agent or solvent is 1g: 10-2000 mL.
3. The process of claim 1 for the preparation of a metal coated stent at low pH, wherein: the main film forming matter is selected from resin and drying oil, the drying in the first step is vacuum freeze drying, the freezing temperature is-10 to-50 ℃, and the vacuum degree is less than or equal to 20 Pa.
4. A process for preparing a metal coated stent for use at low pH according to claim 3, wherein: after the coating is coated, the thickness of the coating after drying and film forming is more than 50 mu m.
5. A process for preparing a metal coated stent for use at low pH according to claim 1, wherein: the inner diameter of the needle head inside the coaxial nozzle is 0.5-1mm, and the inner diameter of the needle head outside the coaxial nozzle is 0.8-1.8 mm.
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Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100371030C (en) * | 2006-01-20 | 2008-02-27 | 重庆大学 | Drug coating-spraying method for drug eluting stent and spraying apparatus therefor |
| US8136475B2 (en) * | 2009-01-06 | 2012-03-20 | The Boeing Company | Controlled environment chamber for applying a coating material to a surface of a member |
| DE102012207819A1 (en) * | 2012-05-10 | 2013-11-14 | Mahle International Gmbh | Slide coating useful for coating the engine modules, preferably pistons, optionally comprising e.g. rings and pins, comprises solid lubricant e.g. graphite, zinc sulfide, optionally heat-curable polymer e.g. polyaryletherketone, and solvent |
| CN103566414B (en) * | 2013-08-13 | 2016-01-13 | 重庆大学 | A kind of nucleocapsid structure receives particulate coatings intravascular stent and preparation method thereof |
| CN104629510B (en) * | 2015-02-03 | 2017-06-27 | 大连理工大学 | The coating peeled off the preparation method of boron nitride anticorrosive paint and its obtain, the application of coating |
| KR20170034726A (en) * | 2015-09-21 | 2017-03-29 | 유재열 | Spray control valve unit and fluid spray apparatus comprising the same |
| CN109590137A (en) * | 2019-01-15 | 2019-04-09 | 中信戴卡股份有限公司 | A kind of wheel ornament ring spray painting positioning fixture |
| TWI708639B (en) * | 2019-11-21 | 2020-11-01 | 亨峰科技有限公司 | Spraying method of ring and the apparatus of the same |
| CN211247086U (en) * | 2019-11-27 | 2020-08-14 | 潍坊春丰新材料科技有限公司 | Nanoscale boron nitride powder spraying device |
| CN212702580U (en) * | 2020-06-16 | 2021-03-16 | 青岛德铸特钢有限公司 | Large-scale mould upset flow coating structure |
| CN214234659U (en) * | 2020-09-27 | 2021-09-21 | 中国二冶集团有限公司 | Pipeline inner wall anticorrosive spraying device |
| CN112246487A (en) * | 2020-09-29 | 2021-01-22 | 杭州麦查居家具有限公司 | Spraying distance adjustable and automatic overturning equipment for hardware parts |
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2021
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