CN113975215A - 一种美白霜及其制备方法 - Google Patents
一种美白霜及其制备方法 Download PDFInfo
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- CN113975215A CN113975215A CN202111368985.XA CN202111368985A CN113975215A CN 113975215 A CN113975215 A CN 113975215A CN 202111368985 A CN202111368985 A CN 202111368985A CN 113975215 A CN113975215 A CN 113975215A
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- parts
- emulsifier
- stirring
- solution
- whitening cream
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- LBQIJVLKGVZRIW-UHFFFAOYSA-N glabridine Natural products C1OC2=C3C=CC(C)(C)OC3=CC=C2CC1C1=CC=C(O)C=C1O LBQIJVLKGVZRIW-UHFFFAOYSA-N 0.000 claims abstract description 23
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Abstract
本发明公开了一种美白霜及其制备方法，涉及美白化妆品技术领域，美白霜包括如下重量份数的原料组分：水31.95‑86.88份、乳化剂1.1‑7份、丁二醇1‑5份、1,2‑戊二醇1‑5份、甘油聚醚‑26 1‑5份、泛醇1‑5份、角鲨烷1‑5份、霍霍巴籽油1‑5份、辛酸癸酸甘油三酯1‑5份、异壬酸异壬酯1‑5份、羟乙基哌嗪乙烷磺酸1‑3份、抗坏血酸四异棕榈酸酯0.5‑4份、光甘草定0.05‑0.1份、海藻糖0.5‑2份、对羟基苯乙酮0.5‑1份、1，2‑己二醇0.5‑1份、姜根提取物溶液0.5‑2份、β‑葡聚糖0.1‑1份、卡波姆0.05‑0.5份、黄原胶0.05‑0.5份、精氨酸0.05‑5份、甘草酸二钾0.1‑0.5份、尿囊素0.1‑0.3份、透明质酸钠0.01‑0.1份、EDTA二钠0.01‑0.05份；所述的乳化剂由乳化剂Olivem 1000、乳化剂Tego Care SE 121和乳化剂Tego Care 450组成；所述的姜根提取物溶液由红没药醇和姜根提取物组成。
Description
技术领域
本发明涉及美白化妆品技术领域，具体涉及一种美白霜及其制备方法。
背景技术
市面上有很多不同种类的美白霜，一些美白霜产品中为了追求快速美白其中采用的美白成分过于刺激，不仅容易造成黑色素细胞死亡而出现白斑，而且还会引起皮肤刺激等症状，敏感肌不可用；此外，一些美白霜中的美白成分对于光热不稳定，不仅容易失去功效活性，而且还会带来副作用。
发明内容
针对现有技术中的缺陷，本发明提供一种美白霜及其制备方法。本发明提供的美白霜可以从内源抑制酪氨酸酶和还原已有黑色素，从外源软化角质，达到内外协同的均匀肤色和祛除痘印斑点，敏感肌也可以使用。
所述的美白霜包括如下重量份数的原料组分：水31.95-86.88份、乳化剂1.1-7份、丁二醇1-5份、1,2-戊二醇1-5份、甘油聚醚-26 1-5份、泛醇1-5份、角鲨烷1-5份、霍霍巴籽油1-5份、辛酸癸酸甘油三酯1-5份、异壬酸异壬酯1-5份、羟乙基哌嗪乙烷磺酸1-3份、抗坏血酸四异棕榈酸酯0.5-4份、光甘草定0.05-0.1份、海藻糖0.5-2份、对羟基苯乙酮0.5-1份、1，2-己二醇0.5-1份、姜根提取物溶液0.5-2份、β-葡聚糖0.1-1份、卡波姆0.05-0.5份、黄原胶0.05-0.5份、精氨酸0.05-5份、甘草酸二钾0.1-0.5份、尿囊素0.1-0.3份、透明质酸钠0.01-0.1份、EDTA二钠0.01-0.05份；所述的乳化剂由乳化剂Olivem 1000、乳化剂TegoCare SE 121和乳化剂Tego Care 450组成；所述的姜根提取物溶液由红没药醇和姜根提取物组成。
优选地，所述的乳化剂Olivem 1000、乳化剂Tego Care SE 121和乳化剂TegoCare 450的重量份数比为0.5-3：0.5-3：0.1-1。
优选地，所述的姜根提取物溶液中红没药醇和姜根提取物的重量份数比为99:1。
上述的美白霜的制备方法，步骤如下：
S1.在四分之一的水中加入精氨酸，搅拌至完全澄清透明，制得精氨酸溶液，备用；
S2.在四分之一的丁二醇中加入对羟基苯乙酮，边加热边搅拌，至完全澄清透明，制得对羟基苯乙酮溶液，备用；
S3.在四分之一的辛酸癸酸甘油三酯中加入光甘草定，边加热边搅拌，至完全澄清透明，制得光甘草定溶液，备用；
S4.将设备进行清洗消毒，备用；
S5.将剩余四分之三的水、剩余四分之三的丁二醇、1,2-戊二醇、甘油聚醚-26、泛醇、海藻糖、卡波姆、黄原胶、甘草酸二钾、尿囊素、透明质酸钠、EDTA二钠依次加入水相锅中，加热搅拌，至完全物颗粒状，保温备用，制得混合溶液A；
S6.将乳化剂、角鲨烷、霍霍巴籽油、剩余四分之三的辛酸癸酸甘油三酯、异壬酸异壬酯加入油相锅中，加热搅拌，至完全物颗粒状，保温备用，制得混合溶液B；
S7.将混合溶液B加入到混合溶液A中，进行均质，至完全均匀状态，保温，第一次降温，加入精氨酸溶液、羟乙基哌嗪乙烷磺酸、抗坏血酸四异棕榈酸酯、β-葡聚糖、对羟基苯乙酮溶液、光甘草定溶液，进行第一次搅拌，第二次降温，加入1，2-己二醇、姜根提取物溶液，进行第二次搅拌，过滤，灌装，包装，制得所述的美白霜。
优选地，步骤S2中，所述的加热为加热至55-65℃。
优选地，步骤S3中，所述的加热为加热至65-75℃。
优选地，步骤S5中，所述的加热为加热至85-90℃，所述的搅拌为在30-50rpm的转速下搅拌10-15分钟。
优选地，步骤S6中，所述的加热为加热至80-85℃，所述的搅拌为在30-50rpm的转速下搅拌10-15分钟。
优选地，步骤S7中，所述的均质为均质10-15分钟，所述的保温为保温5-10分钟，第一次降温为降温至55-60℃，所述的第一次搅拌为在40-60rpm的转速下搅拌5-10分钟，第二次降温为降温至40-45℃，所述的第二次搅拌为在40-60rpm的转速下搅拌5-10分钟。
本发明提供的美白水的用途：可以涂抹于身体各部位。
本发明的有益效果体现在：
(1)本发明提供的美白霜可以从内源抑制酪氨酸酶和还原已有黑色素，从外源软化角质，达到内外协同的均匀肤色和祛除痘印斑点，敏感肌也可以使用。
(2)本发明提供的美白霜采用的原料组分中光甘草定可同时作用酪氨酸酶、DHICA氧化酶、多巴色素互变酶和α-MSH促黑素，和抑制黑色素细胞和B16细胞的增殖，从而达到抑制黑色素生产、抑制黑色素小体转移和减少黑色素总量的作用。另外，采用的抗坏血酸四异棕榈酸酯对光热稳定性好，且有优异的透皮吸收性，转化成维生素C的效率高，可以达到稳定高效的发挥抑制酪氨酸酶和还原黑色素的作用。采用的羟乙基哌嗪乙烷磺酸能软化角质，起到光滑、柔软肌肤、提亮肤色，协助美白的功效。再在具有强大抗炎效果的光甘草定的基础上，搭配了红没药醇、姜(ZINGIBER OFFICINALE)根提取物、甘草酸二钾等抗炎成分，所以敏感肌肤也可以安全使用。
(3)本发明提供的美白霜的制备方法操作简单、技术稳定、原料易得、制得美白霜效果优异，极具商业价值。
具体实施方式
下面将对本发明技术方案的实施例进行详细的描述。以下实施例仅用于更加清楚地说明本发明的技术方案，因此只作为示例，而不能以此来限制本发明的保护范围。
需要注意的是，除非另有说明，本申请使用的技术术语或者科学术语应当为本发明所属领域技术人员所理解的通常意义。
实施例1
本实施例提供了一种美白霜，包括如下重量份数的原料组分：水59.44份、乳化剂4.05份、丁二醇3份、1,2-戊二醇3份、甘油聚醚-26 3份、泛醇3份、角鲨烷3份、霍霍巴籽油3份、辛酸癸酸甘油三酯3份、异壬酸异壬酯3份、羟乙基哌嗪乙烷磺酸2份、抗坏血酸四异棕榈酸酯2.25份、光甘草定0.075份、海藻糖1.25份、对羟基苯乙酮0.75份、1，2-己二醇0.75份、姜根提取物溶液1.25份、β-葡聚糖0.55份、卡波姆0.275份、黄原胶0.275份、精氨酸2.5份、甘草酸二钾0.3份、尿囊素0.2份、透明质酸钠0.055份、EDTA二钠0.03份；
乳化剂由乳化剂Olivem 1000、乳化剂Tego Care SE 121和乳化剂Tego Care450组成，乳化剂Olivem 1000、乳化剂Tego Care SE 121和乳化剂Tego Care450的重量份数比为1.75：1.75：0.55。
姜根提取物溶液由红没药醇和姜根提取物组成，姜根提取物溶液中红没药醇和姜根提取物的重量份数比为99:1。
上述的美白霜的制备方法，步骤如下：
S1.在四分之一的水中加入精氨酸，搅拌至完全澄清透明，制得精氨酸溶液，备用；
S2.在四分之一的丁二醇中加入对羟基苯乙酮，边加热边搅拌，至完全澄清透明，制得对羟基苯乙酮溶液，备用；
S3.在四分之一的辛酸癸酸甘油三酯中加入光甘草定，边加热边搅拌，至完全澄清透明，制得光甘草定溶液，备用；
S4.将设备进行清洗消毒，备用；
S5.将剩余四分之三的水、剩余四分之三的丁二醇、1,2-戊二醇、甘油聚醚-26、泛醇、海藻糖、卡波姆、黄原胶、甘草酸二钾、尿囊素、透明质酸钠、EDTA二钠依次加入水相锅中，加热搅拌，至完全物颗粒状，保温备用，制得混合溶液A；
S6.将乳化剂、角鲨烷、霍霍巴籽油、剩余四分之三的辛酸癸酸甘油三酯、异壬酸异壬酯加入油相锅中，加热搅拌，至完全物颗粒状，保温备用，制得混合溶液B；
S7.将混合溶液B加入到混合溶液A中，进行均质，至完全均匀状态，保温，第一次降温，加入精氨酸溶液、羟乙基哌嗪乙烷磺酸、抗坏血酸四异棕榈酸酯、β-葡聚糖、对羟基苯乙酮溶液、光甘草定溶液，进行第一次搅拌，第二次降温，加入1，2-己二醇、姜根提取物溶液，进行第二次搅拌，过滤，灌装，包装，制得所述的美白霜。
步骤S2中，所述的加热为加热至60℃。
步骤S3中，所述的加热为加热至70℃。
步骤S5中，所述的加热为加热至90℃，所述的搅拌为在40rpm的转速下搅拌15分钟。
步骤S6中，所述的加热为加热至85℃，所述的搅拌为在40rpm的转速下搅拌15分钟。
步骤S7中，所述的均质为均质15分钟，所述的保温为保温10分钟，第一次降温为降温至60℃，所述的第一次搅拌为在50rpm的转速下搅拌10分钟，第二次降温为降温至45℃，所述的第二次搅拌为在50rpm的转速下搅拌10分钟。
实施例2
本实施例提供了一种美白霜，包括如下重量份数的原料组分：水86.88份、乳化剂1.1份、丁二醇1份、1,2-戊二醇1份、甘油聚醚-26 1份、泛醇1份、角鲨烷1份、霍霍巴籽油1份、辛酸癸酸甘油三酯1份、异壬酸异壬酯1份、羟乙基哌嗪乙烷磺酸1份、抗坏血酸四异棕榈酸酯0.5份、光甘草定0.05份、海藻糖0.5份、对羟基苯乙酮0.5份、1，2-己二醇0.5份、姜根提取物溶液0.5份、β-葡聚糖0.1份、卡波姆0.05份、黄原胶0.05份、精氨酸0.05份、甘草酸二钾0.1份、尿囊素0.1份、透明质酸钠0.01份、EDTA二钠0.01份；
乳化剂由乳化剂Olivem 1000、乳化剂Tego Care SE 121和乳化剂Tego Care450组成，乳化剂Olivem 1000、乳化剂Tego Care SE 121和乳化剂Tego Care450的重量份数比为0.5：0.5：0.1。
姜根提取物溶液由红没药醇和姜根提取物组成，姜根提取物溶液中红没药醇和姜根提取物的重量份数比为99:1。
上述的美白霜的制备方法，步骤如下：
S1.在四分之一的水中加入精氨酸，搅拌至完全澄清透明，制得精氨酸溶液，备用；
S2.在四分之一的丁二醇中加入对羟基苯乙酮，边加热边搅拌，至完全澄清透明，制得对羟基苯乙酮溶液，备用；
S3.在四分之一的辛酸癸酸甘油三酯中加入光甘草定，边加热边搅拌，至完全澄清透明，制得光甘草定溶液，备用；
S4.将设备进行清洗消毒，备用；
S5.将剩余四分之三的水、剩余四分之三的丁二醇、1,2-戊二醇、甘油聚醚-26、泛醇、海藻糖、卡波姆、黄原胶、甘草酸二钾、尿囊素、透明质酸钠、EDTA二钠依次加入水相锅中，加热搅拌，至完全物颗粒状，保温备用，制得混合溶液A；
S6.将乳化剂、角鲨烷、霍霍巴籽油、剩余四分之三的辛酸癸酸甘油三酯、异壬酸异壬酯加入油相锅中，加热搅拌，至完全物颗粒状，保温备用，制得混合溶液B；
S7.将混合溶液B加入到混合溶液A中，进行均质，至完全均匀状态，保温，第一次降温，加入精氨酸溶液、羟乙基哌嗪乙烷磺酸、抗坏血酸四异棕榈酸酯、β-葡聚糖、对羟基苯乙酮溶液、光甘草定溶液，进行第一次搅拌，第二次降温，加入1，2-己二醇、姜根提取物溶液，进行第二次搅拌，过滤，灌装，包装，制得所述的美白霜。
步骤S2中，所述的加热为加热至60℃。
步骤S3中，所述的加热为加热至70℃。
步骤S5中，所述的加热为加热至90℃，所述的搅拌为在40rpm的转速下搅拌15分钟。
步骤S6中，所述的加热为加热至85℃，所述的搅拌为在40rpm的转速下搅拌15分钟。
步骤S7中，所述的均质为均质15分钟，所述的保温为保温10分钟，第一次降温为降温至60℃，所述的第一次搅拌为在50rpm的转速下搅拌10分钟，第二次降温为降温至45℃，所述的第二次搅拌为在50rpm的转速下搅拌10分钟。
实施例3
一种美白霜，其特征在于：所述的美白霜包括如下重量份数的原料组分：水31.95份、乳化剂7份、丁二醇5份、1,2-戊二醇5份、甘油聚醚-26 5份、泛醇5份、角鲨烷5份、霍霍巴籽油5份、辛酸癸酸甘油三酯5份、异壬酸异壬酯5份、羟乙基哌嗪乙烷磺酸3份、抗坏血酸四异棕榈酸酯4份、光甘草定0.1份、海藻糖2份、对羟基苯乙酮1份、1，2-己二醇1份、姜根提取物溶液2份、β-葡聚糖1份、卡波姆0.5份、黄原胶0.5份、精氨酸5份、甘草酸二钾0.5份、尿囊素0.3份、透明质酸钠0.1份、EDTA二钠0.05份；
乳化剂由乳化剂Olivem 1000、乳化剂Tego Care SE 121和乳化剂Tego Care450组成，乳化剂Olivem 1000、乳化剂Tego Care SE 121和乳化剂Tego Care450的重量份数比为3：3：1。
姜根提取物溶液由红没药醇和姜根提取物组成，姜根提取物溶液中红没药醇和姜根提取物的重量份数比为99:1。
上述的美白霜的制备方法，步骤如下：
S1.在四分之一的水中加入精氨酸，搅拌至完全澄清透明，制得精氨酸溶液，备用；
S2.在四分之一的丁二醇中加入对羟基苯乙酮，边加热边搅拌，至完全澄清透明，制得对羟基苯乙酮溶液，备用；
S3.在四分之一的辛酸癸酸甘油三酯中加入光甘草定，边加热边搅拌，至完全澄清透明，制得光甘草定溶液，备用；
S4.将设备进行清洗消毒，备用；
S5.将剩余四分之三的水、剩余四分之三的丁二醇、1,2-戊二醇、甘油聚醚-26、泛醇、海藻糖、卡波姆、黄原胶、甘草酸二钾、尿囊素、透明质酸钠、EDTA二钠依次加入水相锅中，加热搅拌，至完全物颗粒状，保温备用，制得混合溶液A；
S6.将乳化剂、角鲨烷、霍霍巴籽油、剩余四分之三的辛酸癸酸甘油三酯、异壬酸异壬酯加入油相锅中，加热搅拌，至完全物颗粒状，保温备用，制得混合溶液B；
S7.将混合溶液B加入到混合溶液A中，进行均质，至完全均匀状态，保温，第一次降温，加入精氨酸溶液、羟乙基哌嗪乙烷磺酸、抗坏血酸四异棕榈酸酯、β-葡聚糖、对羟基苯乙酮溶液、光甘草定溶液，进行第一次搅拌，第二次降温，加入1，2-己二醇、姜根提取物溶液，进行第二次搅拌，过滤，灌装，包装，制得所述的美白霜。
步骤S2中，所述的加热为加热至60℃。
步骤S3中，所述的加热为加热至70℃。
步骤S5中，所述的加热为加热至90℃，所述的搅拌为在40rpm的转速下搅拌15分钟。
步骤S6中，所述的加热为加热至85℃，所述的搅拌为在40rpm的转速下搅拌15分钟。
步骤S7中，所述的均质为均质15分钟，所述的保温为保温10分钟，第一次降温为降温至60℃，所述的第一次搅拌为在50rpm的转速下搅拌10分钟，第二次降温为降温至45℃，所述的第二次搅拌为在50rpm的转速下搅拌10分钟。
实施例1
测试实施例1制得的美白霜的效果
测试方法：随机选取本地20-57岁测试者，性别不限，连续使用实施例1提供的美白霜，早晚各一次，一次2g，均匀涂抹于面部，测试测试者皮肤黑色素数值，结过见表1。
表1
从表1可知，连续使用本发明实施例1提供的美白霜28天可以显著达到美白的效果。
最后应说明的是：以上各实施例仅用以说明本发明的技术方案，而非对其限制；尽管参照前述各实施例对本发明进行了详细的说明，本领域的普通技术人员应当理解：其依然可以对前述各实施例所记载的技术方案进行修改，或者对其中部分或者全部技术特征进行等同替换；而这些修改或者替换，并不使相应技术方案的本质脱离本发明各实施例技术方案的范围，其均应涵盖在本发明的权利要求和说明书的范围当中。
Claims (9)
1.一种美白霜，其特征在于：所述的美白霜包括如下重量份数的原料组分：水31.95-86.88份、乳化剂1.1-7份、丁二醇1-5份、1,2-戊二醇1-5份、甘油聚醚-26 1-5份、泛醇1-5份、角鲨烷1-5份、霍霍巴籽油1-5份、辛酸癸酸甘油三酯1-5份、异壬酸异壬酯1-5份、羟乙基哌嗪乙烷磺酸1-3份、抗坏血酸四异棕榈酸酯0.5-4份、光甘草定0.05-0.1份、海藻糖0.5-2份、对羟基苯乙酮0.5-1份、1，2-己二醇0.5-1份、姜根提取物溶液0.5-2份、β-葡聚糖0.1-1份、卡波姆0.05-0.5份、黄原胶0.05-0.5份、精氨酸0.05-5份、甘草酸二钾0.1-0.5份、尿囊素0.1-0.3份、透明质酸钠0.01-0.1份、EDTA二钠0.01-0.05份；所述的乳化剂由乳化剂Olivem 1000、乳化剂Tego Care SE 121和乳化剂Tego Care 450组成；所述的姜根提取物溶液由红没药醇和姜根提取物组成。
2.根据权利要求1所述的美白霜，其特征在于：所述的乳化剂Olivem 1000、乳化剂TegoCare SE 121和乳化剂Tego Care 450的重量份数比为0.5-3：0.5-3：0.1-1。
3.根据权利要求1所述的美白霜，其特征在于：所述的姜根提取物溶液中红没药醇和姜根提取物的重量份数比为99:1。
4.权利要求1-3任一所述的美白霜的制备方法，其特征在于：所述的制备方法，步骤如下：
S1.在四分之一的水中加入精氨酸，搅拌至完全澄清透明，制得精氨酸溶液，备用；
S2.在四分之一的丁二醇中加入对羟基苯乙酮，边加热边搅拌，至完全澄清透明，制得对羟基苯乙酮溶液，备用；
S3.在四分之一的辛酸癸酸甘油三酯中加入光甘草定，边加热边搅拌，至完全澄清透明，制得光甘草定溶液，备用；
S4.将设备进行清洗消毒，备用；
S5.将剩余四分之三的水、剩余四分之三的丁二醇、1,2-戊二醇、甘油聚醚-26、泛醇、海藻糖、卡波姆、黄原胶、甘草酸二钾、尿囊素、透明质酸钠、EDTA二钠依次加入水相锅中，加热搅拌，至完全物颗粒状，保温备用，制得混合溶液A；
S6.将乳化剂、角鲨烷、霍霍巴籽油、剩余四分之三的辛酸癸酸甘油三酯、异壬酸异壬酯加入油相锅中，加热搅拌，至完全物颗粒状，保温备用，制得混合溶液B；
S7.将混合溶液B加入到混合溶液A中，进行均质，至完全均匀状态，保温，第一次降温，加入精氨酸溶液、羟乙基哌嗪乙烷磺酸、抗坏血酸四异棕榈酸酯、β-葡聚糖、对羟基苯乙酮溶液、光甘草定溶液，进行第一次搅拌，第二次降温，加入1，2-己二醇、姜根提取物溶液，进行第二次搅拌，过滤，灌装，包装，制得所述的美白霜。
5.根据权利要求4所述的美白霜的制备方法，其特征在于：步骤S2中，所述的加热为加热至55-65℃。
6.根据权利要求4所述的美白霜的制备方法，其特征在于：步骤S3中，所述的加热为加热至65-75℃。
7.根据权利要求4所述的美白霜的制备方法，其特征在于：步骤S5中，所述的加热为加热至85-90℃，所述的搅拌为在30-50rpm的转速下搅拌10-15分钟。
8.根据权利要求4所述的美白霜的制备方法，其特征在于：步骤S6中，所述的加热为加热至80-85℃，所述的搅拌为在30-50rpm的转速下搅拌10-15分钟。
9.根据权利要求4所述的美白霜的制备方法，其特征在于：步骤S7中，所述的均质为均质10-15分钟，所述的保温为保温5-10分钟，第一次降温为降温至55-60℃，所述的第一次搅拌为在40-60rpm的转速下搅拌5-10分钟，第二次降温为降温至40-45℃，所述的第二次搅拌为在40-60rpm的转速下搅拌5-10分钟。
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