CN113974769B

CN113974769B - Thrombus aspiration catheter

Info

Publication number: CN113974769B
Application number: CN202111372527.3A
Authority: CN
Inventors: 成立萍; 赵振心; 朱佳英
Original assignee: Skynor Medical Technology Shanghai Co ltd
Current assignee: Skynor Medical Technology Shanghai Co ltd
Priority date: 2021-11-19
Filing date: 2021-11-19
Publication date: 2022-12-20
Anticipated expiration: 2041-11-19
Also published as: CN113974769A

Abstract

The invention provides a thrombus aspiration catheter, which comprises a catheter seat, a stress release tube, a catheter body and a developing mark, wherein the catheter seat is provided with a stress release hole; when thrombus is sucked, the blood vessel can be blocked so as to prevent broken fine thrombus from flowing to the blood vessel with a smaller far end, more importantly, the thrombus can be broken and cut by thrombus breaking equipment at the tail end of the catheter in the sucking process, so that old thrombus or hard thrombus can be smoothly sucked and taken out, the success rate of an operation is greatly improved, and the risk of the operation is reduced; has great significance for reducing complications and improving the suction effect of thrombus.

Description

Thrombus aspiration catheter

Technical Field

The invention belongs to the technical field of medical instruments, and particularly relates to a thrombus aspiration catheter for cardiovascular intervention.

Background

Thrombi are small patches formed by the surface of blood flow at a denuded or repaired site within a blood vessel of the cardiovascular system. In the variable fluid dependence, the thrombus consists of insoluble fibrin, deposited platelets, accumulated white blood cells and entrapped red blood cells. If thrombus is blocked in blood vessels of a human body, blood flow is interrupted, and diseases such as myocardial infarction, cerebral apoplexy and the like which can endanger life are easily caused.

At present, thrombolytic therapy is still the mainstream treatment mode for ischemic stroke, and has certain limitations, mainly embodied in short treatment time window and low revascularization rate. The mechanical thrombus extraction treatment mode has obvious advantages in treatment effect, and the currently common mechanical thrombus extraction mode is direct negative pressure suction of a suction catheter to suck thrombus out of a blood vessel so as to reconstruct the blood vessel. However, the thrombus is generally divided into acute fresh thrombus and old thrombus, and as for the old thrombus, the size is large, the old thrombus is hard, and the old thrombus is difficult to be directly sucked out by using a thrombus suction catheter, and clinically, the old thrombus with large size needs to be firstly separated by using a thrombus separator, and then the old thrombus is sucked by using the thrombus suction catheter, so that the difficulty of the operation is increased, the operation time of the operation is greatly prolonged, and the operation is obviously unsuitable for the stroke of which the time is life.

Disclosure of Invention

The invention aims to overcome the defects in the prior art, and designs a thrombus aspiration catheter which can be used for plugging a blood vessel when thrombus is aspirated so as to prevent broken fine thrombus from flowing to the blood vessel with a smaller far end, more importantly, the thrombus can be broken and cut by a thrombus breaking device at the tail end of the catheter in the aspiration process, so that old thrombus or hard thrombus can be smoothly taken out through aspiration, the success rate of an operation is greatly improved, and the risk of the operation is reduced; has great significance for reducing complications and improving the aspiration effect of thrombus.

In order to achieve the above object, the technical solution of the present invention is to provide a thrombus aspiration catheter, which comprises a catheter holder, a stress release tube, a catheter body and a visualization mark, wherein the catheter holder is connected with the catheter body through the stress release tube, the catheter body is composed of three layers of an inner tube, an intermediate layer and an outer tube, the inner tube and the outer tube are composed of polymer materials, and the intermediate layer is composed of metal wires; the method is characterized in that: the catheter seat is provided with a main channel and a side channel, the main channel is connected with the suction cavity, and the side channel is connected with the liquid through cavity; the side wall of the far end of the outer tube is provided with a liquid through hole, and the outer side of the liquid through hole is provided with a saccule; the inner tube at the tail end of the catheter body is connected with equipment capable of breaking thrombus, and the equipment capable of breaking thrombus is an ultrasonic transducer or a cutting blade; the ultrasonic transducer is positioned in the middle layer of the tail end of the catheter, and the cutting blade is connected to the inner tube of the tail end of the catheter; is connected with the inner tube at the tail end of the catheter.

Furthermore, the tail end of the catheter body is in a bevel opening shape.

Furthermore, the equipment capable of breaking thrombus comprises a blade, and the blade is positioned on the upper half part of the equipment and faces to the outlet of the catheter at the end of the catheter. When the thrombus is sucked, the old thrombus or the thrombus with relatively hard texture is broken through the suction force and the action of the knife edge. The cutting edge can be connected to the periphery of the inner tube at the tail end of the catheter or can be connected to the tail end of the whole catheter in a net shape; it may be in a circular shape concentric with the catheter or any other shape that can be cut.

Furthermore, the equipment capable of breaking thrombus has a blade-free area and a blade-free area in the radial direction towards the tail end, and the height of the blade-free area is greater than the length from the position where the blade is arranged to the extreme edge of the catheter; the distance between the blade edge area and the wall of the conduit is greater than the length from the position where the blade edge is arranged to the most edge of the conduit.

Further, the material of the equipment capable of breaking thrombus is one or a mixture of more of silicon rubber, medical metal and medical plastic, and preferably the silicon rubber.

Further, the balloon is a compliance balloon, and the volume of the balloon can be gradually increased along with the filling of outside liquid or other filling so as to play a role in blocking the blood vessel.

Further, the balloon comprises not less than 2 balloons which are arranged in series, and preferably 3 balloons which are arranged in series.

Further, the balloons in the continuous arrangement gradually decrease in effective length from the proximal end to the distal end in the unfilled state.

Compared with the prior art, the invention has the following beneficial effects: when thrombus is sucked, the thrombus suction catheter can be used for plugging blood vessels so as to prevent broken fine thrombus from flowing to blood vessels with smaller far ends and further prevent the blood vessels at the far ends from being blocked; more importantly, the suction device can suck the thrombus through the suction force of the suction and the breakable equipment, particularly, the thrombus can be broken aiming at old thrombus or hard thrombus, the efficiency of thrombus suction is improved better, and the suction device has great significance for reducing complications and improving the suction effect of the thrombus.

Drawings

In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings used in the description of the embodiments will be briefly introduced below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art that other drawings can be obtained according to the drawings without creative efforts.

Fig. 1 is a schematic view showing the construction of a thrombus aspiration catheter of the present invention.

FIG. 2 is a radial cross-sectional view of the thrombus aspiration catheter of the present invention.

FIG. 2A is a radial cross-sectional view of the beveled end of the thrombus extraction catheter of the present invention.

Fig. 3 is an enlarged schematic structural view of thrombus crushing equipment of the thrombus suction catheter of the invention.

Fig. 4A is a schematic view of a blade of the thrombus-breaking device of the present invention.

Fig. 4B is a schematic view of another blade of the thrombus-breaking device of the present invention.

Fig. 4C is another schematic view of a blade of the thrombus-disrupting apparatus of this patent.

Fig. 4D is a schematic view of another blade of the thrombus-disrupting apparatus of the present invention.

Detailed Description

In order to make the aforementioned objects, features and advantages of the present invention more comprehensible, embodiments accompanying figures are described in detail below. In describing the embodiments of the present invention in detail, the drawings are not necessarily to scale, and should not be taken as limiting the invention;

example 1

As shown in fig. 1, a thrombus aspiration catheter comprises a catheter holder, a stress relief tube, a catheter body and a developing mark, wherein the catheter holder is connected with the catheter body through the stress relief tube; the catheter body is composed of three layers of structures, namely an inner tube, a middle layer and an outer tube, wherein the inner tube and the outer tube are composed of polyether block amide Pebax and polyurethane PU, and the middle layer is composed of 304 stainless steel wires; the method is characterized in that: the catheter seat is provided with a main channel and a side channel, the main channel is connected with the suction cavity, and the side channel is connected with the liquid through cavity; the lateral wall of outer tube distal end be equipped with logical liquid hole 3, lead to the liquid hole outside and be equipped with sacculus 4. As shown in fig. 2 and 3, the inner tube at the tail end of the catheter body is connected with a thrombus breaking device 5 which is a cutting blade; the cutting blade is connected with the inner tube at the tail end of the catheter; is connected with the inner tube at the tail end of the catheter.

As shown in fig. 4A, the thrombus breaking device comprises a net-shaped blade, which is positioned on the upper half part of the device and faces the outlet of the catheter at the end of the catheter. When the distal end of the catheter reaches the thrombus for suction, old thrombus or hard thrombus is broken along the cutting edge and sucked into the catheter to be removed due to the suction force and the cutting edge.

As can be seen in fig. 4A, 4B, 4C and 4D, the blade of the thrombus-disrupting instrument is divided into a blade-free region 6 and a blade region 7; the height of the non-blade area is larger than the length from the blade mounting position to the extreme edge of the conduit; the distance between the blade edge region and the wall of the conduit is greater than the length from the position where the blade edge is mounted to the extreme edge of the conduit.

The developing mark of the conduit is made of platinum-iridium alloy; the material of the breakable equipment is silicon rubber.

The balloon is a compliant silica gel balloon, and the volume of the balloon is gradually increased along with the filling of the contrast agent, so that the balloon plays a role in blocking a blood vessel.

The balloon comprises 3 balloons which are arranged in series, and the effective length of the 3 balloons is gradually reduced from the proximal end to the distal end in the unfilled state.

Example 2

As shown in fig. 1, a thrombus aspiration catheter comprises a catheter holder, a stress relief tube, a catheter body and a developing mark, wherein the catheter holder is connected with the catheter body through the stress relief tube; the catheter body is composed of an inner tube, a middle layer and an outer tube which are of a three-layer structure, wherein the inner tube and the outer tube are composed of polyether block amide Pebax and nylon PA, and the middle layer is composed of nickel-titanium alloy wires; the method is characterized in that: the outer tube is composed of two layers of structures, the inner cavity of the inner tube is a suction cavity 1, a liquid through cavity 2 is formed between the two layers of structures of the outer tube, the catheter seat is provided with a main channel and a side channel, the main channel is connected with the suction cavity, and the side channel is connected with the liquid through cavity; the lateral wall of outer tube distal end be equipped with logical liquid hole 3, lead to the liquid hole outside and be equipped with sacculus 4. The tail end of the catheter body is in an oblique mouth shape; as shown in fig. 2A and 3, the inner tube at the tail end of the catheter body is connected with a thrombus breaking device 5 which is a cutting blade; the cutting blade is connected with the inner tube at the tail end of the catheter; is connected with the inner pipe of the nearest section of the tail end bevel opening of the guide pipe.

As shown in fig. 4B, the device for breaking thrombus comprises fan-shaped blades uniformly distributed around the inner tube at the end of the catheter body; the knife edge is located in the upper half of the device, which faces the outlet of the catheter at the end of the catheter. When the distal end of the catheter reaches the thrombus for suction, old thrombus or hard thrombus is broken along the cutting edge and sucked into the catheter for removal due to the suction force and the cutting edge.

As can be seen in fig. 4A, 4B, 4C and 4D, the blade of the thrombus-disrupting instrument is divided into a non-blade region 6 and a blade region 7; the height of the non-blade area is larger than the length from the blade mounting position to the extreme edge of the conduit; the distance between the blade edge region and the wall of the conduit is greater than the length from the position where the blade edge is mounted to the extreme edge of the conduit.

The developing mark of the catheter is made of platinum-iridium alloy; the material of the breakable equipment is metal.

The far end of the outer tube of the thrombus aspiration catheter contains a compliance sacculus, and the sacculus is gradually increased in volume by filling contrast medium in clinical operation, thereby playing a role in blocking blood vessels.

The above description is only for the purpose of describing the preferred embodiments of the present invention, and is not intended to limit the scope of the present invention, and any variations and modifications made by those skilled in the art based on the above disclosure are within the scope of the appended claims.

Claims

1. A thrombus aspiration catheter comprises a catheter seat, a stress release tube, a catheter body and a developing mark, wherein the catheter seat is connected with the catheter body through the stress release tube; the method is characterized in that: the catheter seat is provided with a main channel and a side channel, the main channel is connected with the suction cavity, and the side channel is connected with the liquid through cavity; the side wall of the far end of the outer tube is provided with a liquid through hole (3), and the outer side of the liquid through hole is provided with a saccule (4); the outer pipe and the inner pipe are made of polyether block amide and polyurethane; the inner tube at the tail end of the catheter body is connected with equipment (5) capable of breaking thrombus; the equipment for breaking thrombus contains a non-blade area (6) and a blade area (7), and the height of the non-blade area is greater than the length from the installation position of the equipment for breaking thrombus to the extreme edge of the catheter; the cutting edge of the equipment capable of breaking thrombus faces the end of the catheter.

2. A thrombus aspiration catheter according to claim 1, wherein: the tail end of the catheter body is in a bevel opening shape.

3. A thrombus aspiration catheter according to claim 1, wherein: the distance between the blade area and the wall of the conduit is greater than the length from the position where the blade area is installed to the most edge of the conduit.

4. A thrombus aspiration catheter according to claim 1, wherein: the material of the equipment capable of breaking thrombus is one or a mixture of more of silicon rubber, medical metal and medical plastic.

5. A thrombus aspiration catheter according to claim 1, wherein: the developing mark (8) is made of one or a mixture of more of platinum-iridium alloy, platinum-tungsten alloy, gold and tantalum alloy.

6. A thrombus aspiration catheter according to claim 1, wherein: the balloon is made of a compliant balloon.

7. A thrombus aspiration catheter according to claim 1, wherein: the sacculus comprises not less than 2 sacculus that arrange in succession.

8. A thrombus aspiration catheter according to claim 7, wherein: the balloon arranged in series gradually decreases in effective length from the proximal end to the distal end in the unfilled state.