CN113967125A - Micro-pressure fluctuation detection system and detection method thereof - Google Patents
Micro-pressure fluctuation detection system and detection method thereof Download PDFInfo
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- CN113967125A CN113967125A CN202111233588.1A CN202111233588A CN113967125A CN 113967125 A CN113967125 A CN 113967125A CN 202111233588 A CN202111233588 A CN 202111233588A CN 113967125 A CN113967125 A CN 113967125A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00781—Apparatus for modifying intraocular pressure, e.g. for glaucoma treatment
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M39/00—Tubes, tube connectors, tube couplings, valves, access sites or the like, specially adapted for medical use
- A61M39/22—Valves or arrangement of valves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2205/00—General characteristics of the apparatus
- A61M2205/33—Controlling, regulating or measuring
- A61M2205/3331—Pressure; Flow
Abstract
The invention discloses a trace pressure fluctuation detection system and a detection method thereof, and the trace pressure fluctuation detection system comprises a main control system, a pressure generation system connected with the main control system through a connecting lead, a sample fixing system connected with the pressure generation system through a micro pipeline, and a pressure measurement system connected with the sample fixing system through a micro pipeline, wherein the pressure measurement system is connected with the main control system through a connecting lead. The device is used for detecting the pressure fluctuation of the surface pipeline of the drainage valve of the glaucoma aqueous humor drainage device, accurately detects the pressure of the special microenvironment pipeline opened and closed by the valve, provides a technical platform for the industrial development of the novel aqueous humor drainage device, and is used for performance detection and quality evaluation. The micro-pressure fluctuation detection system of the glaucoma aqueous humor drainage device has the advantages of simple structure, reliable detection method and high validity of detection results.
Description
Technical Field
The invention relates to the technical field of medical instruments, in particular to a trace pressure fluctuation detection system and a detection method thereof.
Background
Glaucoma is a persistent optic nerve degenerative disease which is mainly characterized by increased intraocular pressure and is also the first irreversible blinding eye disease in the world. Ocular hypotensive therapy is the only proven means to slow the progression of glaucoma.
In clinical practice, the intraocular pressure reducing eye drops are most accepted by patients, but face a plurality of medication difficulties. When eye drops are topically administered, there are dynamic barriers (tear dilution and conjunctival absorption, transport, etc.) and corneal static barriers (corneal epithelium, stroma, and endothelial layer), which directly result in low ocular concentrations of hypotensive drugs and poor patient compliance, and many mild patients develop moderate-severe, refractory glaucoma, even complete blindness.
For refractory glaucoma, the current primary treatment regimen is the implantation of an aqueous humor drainage device, due to the difficulty of effective treatment by conventional means. Aqueous humor Drainage device implants (ADDs) can regulate the intraocular pressure to fluctuate within a reasonable range, and maintain a good intraocular pressure environment. The opening and closing pressure of the valve of the aqueous humor drainage device is the key for controlling intraocular pressure, and the accurate detection of pressure fluctuation is always a difficult problem, so that the industrialized research and development progress of the novel glaucoma aqueous humor drainage device is directly influenced. In the aspect of trace pipeline pressure detection, current patent CN201080041968.9 and CN201910247100.7, read pressure sensing from the controller respectively and adjust the active valve, cavity intracavity pressure change (>12mmHg) is with the angle of control pressure valve switch, novel glaucomatous aqueous humor drainage valve device has been designed for the cavity internal pressure detection of pressure valve, wherein mainly involve sensing control technique and manufacturing technology, these techniques still exist the device structure too complicated, to the not enough scheduling problem of pressure change's sensitivity, be difficult to satisfy the actual need of novel glaucomatous aqueous humor drainage device drainage valve pressure accurate detection. Therefore, there is a need for a system and a method for detecting the pressure fluctuation of the trace amount in the drainage device, which can solve the above problems.
Disclosure of Invention
In order to solve the technical problems, the technical scheme of the invention provides a trace pressure fluctuation detection system, which comprises a main control system, a pressure generation system connected with the main control system through a connecting lead, a sample fixing system connected with the pressure generation system through a micro pipeline, and a pressure measurement system connected with the sample fixing system through a micro pipeline, wherein the pressure measurement system is connected with the main control system through a connecting lead; the pressure measuring system senses the pressure fluctuation condition in the sample fixing system in real time, converts and amplifies the pressure fluctuation condition into an electric signal and transmits the electric signal to the main control system, and the main control system displays the electric signal in a data curve form.
Optionally, the master control system comprises a computer host, a computer display, and pressure control and measurement software built in the computer host.
Optionally, the pressure generating system includes a sliding controller, an electric sliding rail, a sliding component slidably disposed on the electric sliding rail, a water tank fixed on the sliding component, and a micro-pipe switch, and the sliding controller is connected to the computer host through a connecting wire.
Optionally, the sample fixing system comprises a fixing base, a sample fixing head installed on the fixing base, and a glaucoma aqueous humor drainage device fixed on the fixing base through the sample fixing head, wherein the glaucoma aqueous humor drainage valve device sample is connected to the pressure pipeline interface of the water tank through a three-way valve and a micro pipeline.
Optionally, the pressure measurement system includes pressure sensor probe, data acquisition instrument and sensor output switching power supply, the pressure sensor probe passes through the micro-pipeline, the three-way valve with glaucoma aqueous humor drainage device is connected, the data acquisition instrument pass through connecting wire with computer is connected.
In order to solve the above technical problem, the technical solution of the present invention further provides a detection method of a trace pressure fluctuation detection system, wherein the detection method comprises:
adjusting pressure control and measurement software in the main control system, closing a micro-pipeline switch of the pressure generation system, setting a corresponding gravity water pressure value, realizing the set gravity water pressure by the operation of the water tank along the sliding rail, opening the micro-pipeline switch of the pressure generation system, detecting the pressure fluctuation condition of the pipeline on the surface of the drainage valve of the glaucoma aqueous humor drainage device by the pressure measurement system, and realizing data reading, storage and graphic processing by a computer host and a computer display of the main control system.
Optionally, the pressure generation system adopts a fixed pressure mode, and the pressure is set to a specific gravity water pressure value; the fixed pressure value is in the range of 3-40 mmHg; the fixed pressure values were 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20 mmHg.
Optionally, the pressure generating system adopts a pressure increasing mode, the pressure is set to a continuously increasing gravitational water pressure value, and the continuously increasing gravitational water pressure value is realized by the continuously lifted water tank; continuously increasing the pressure to 3mmHg at the initial position and 40mmHg at the final position; the lifting speed is 0.1-10 mmHg/min; in particular.
Optionally, the pressure generation system adopts a cyclic fluctuation pressure mode, the pressure is set to be a cyclic gravity water pressure value of continuous increase, continuous decrease and continuous increase, and the cyclic fluctuation gravity water pressure value is realized by circularly lifting the water tank; the initial position of the circulation fluctuation pressure is 3mmHg, and after the pressure reaches 40mmHg, the pressure is reduced to 3mmHg, and the lifting speed is 0.1-10 mmHg/min.
The technical scheme of the invention has the beneficial effects that:
the invention provides a trace pressure fluctuation detection system and a detection method, which are used for detecting the pressure fluctuation condition of a pipeline on the surface of a drainage valve of a glaucoma aqueous humor drainage device, accurately detecting the pressure of a pipeline with a special microenvironment for opening and closing the valve, providing a technical platform for the industrial development of a novel aqueous humor drainage device, and being used for performance detection and quality evaluation. The micro-pressure fluctuation detection system of the glaucoma aqueous humor drainage device has the advantages of simple structure, reliable detection method and high validity of detection results.
Drawings
FIG. 1 is a schematic structural diagram of a trace pressure fluctuation detection system according to an embodiment of the present invention.
The specific implementation mode is as follows:
the invention is further described with reference to the following drawings and specific examples, which are not intended to be limiting.
In the present invention, unless otherwise expressly specified or limited, the terms "mounted," "connected," "secured," and the like are to be construed broadly and can, for example, be fixedly connected, detachably connected, or integrally connected; can be mechanically or electrically connected; they may be connected directly or indirectly through intervening media, or they may be interconnected between two elements. The specific meanings of the above terms in the present invention can be understood by those skilled in the art according to specific situations.
In the present invention, unless otherwise expressly stated or limited, "above" or "below" a first feature means that the first and second features are in direct contact, or that the first and second features are not in direct contact but are in contact with each other via another feature therebetween. Also, the first feature being "on," "above" and "over" the second feature includes the first feature being directly on and obliquely above the second feature, or merely indicating that the first feature is at a higher level than the second feature. A first feature being "under," "below," and "beneath" a second feature includes the first feature being directly above and obliquely above the second feature, or simply meaning that the first feature is at a lesser level than the second feature.
Referring to fig. 1, a micro pressure fluctuation detection system of an embodiment is shown, which includes a main control system 1, a pressure generating system 2 connected to the main control system 1 through a connecting wire 7, a sample fixing system 3 connected to the pressure generating system 2 through a micro-pipe 6, and a pressure measuring system 4 connected to the sample fixing system 3 through the micro-pipe 6, wherein the pressure measuring system 4 is connected to the main control system 1 through a connecting wire 7; the main control system 1 controls to transmit a pressure value to be measured to the pressure generating system 2 through an instruction, the pressure generating system 2 generates corresponding physical pressure and transmits the physical pressure to the sample fixing system 3, the sample fixing system 3 receives the physical pressure given by the pressure generating system, the pressure measuring system 4 senses the pressure fluctuation condition in the sample fixing system 3 in real time, converts and amplifies the pressure fluctuation condition into an electric signal and transmits the electric signal to the main control system 1, and the main control system 1 displays the electric signal in a data curve form.
In this embodiment, the main control system 1 includes a host computer 11, a computer monitor 12, and pressure control and measurement software built in the host computer 11.
In this embodiment, the pressure generating system 2 includes a sliding controller 21, an electric slide rail 22, a sliding component 23 slidably disposed on the electric slide rail 22, a water tank 24 fixed on the sliding component 23, and a micro-pipe switch 25, wherein the sliding controller 21 is connected to the computer host 11 through a connecting wire 7.
In this embodiment, the sample fixing system 3 includes a fixing base 31, a sample fixing head 32 installed on the fixing base 31, and a glaucoma aqueous humor drainage device sample 33 fixed on the fixing base 31 through the sample fixing head 32, wherein the glaucoma aqueous humor drainage valve device sample 33 is connected to the pressure micro-pipeline switch 25 of the water tank 24 through the three-way valve 5 and the micro-pipeline 6.
In this embodiment, the pressure measurement system 4 includes a pressure sensor probe 41, a data acquisition instrument 42 and a sensor output switch power supply, the pressure sensor probe 41 is connected with the glaucoma aqueous humor drainage device sample 33 through the micro-pipe 6 and the three-way valve 5, and the data acquisition instrument 42 is connected with the host computer 11 through the connecting wire 7.
The features and functions of the present invention will be further understood from the following description.
The embodiment also provides a detection method of the trace pressure fluctuation detection system, wherein the detection method comprises the following steps:
adjusting pressure control and measurement software in the main control system 1, closing a micro-pipeline switch 25 of the pressure generation system 2, setting a corresponding gravity water pressure value, realizing the set gravity water pressure by running a water tank 24 along a slide rail 22, opening the micro-pipeline switch 25 of the pressure generation system 2, detecting the surface pipeline pressure fluctuation condition of a drainage valve of a glaucoma aqueous humor drainage device sample 33 through a pressure measurement system 4, and realizing data reading, storage and graphic processing through a computer host 11 and a computer display 12 of the main control system 1.
Optionally, the pressure generating system 2 adopts a fixed pressure mode, and the pressure is set to a specific gravity water pressure value; the fixed pressure value is in the range of 3-40 mmHg; in particular, the fixed pressure value is in the range of 5-20 mmHg; specifically, the fixed pressure values were 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20 mmHg.
Optionally, the pressure generating system 2 adopts a pressure increasing mode, the pressure is set to a continuously increasing gravity water pressure value, and the continuously increasing gravity water pressure value is realized by a continuously lifting water tank; continuously increasing the pressure to 3mmHg at the initial position and 40mmHg at the final position; specifically, the pressure was continuously increased at the initial position of 5mmHg and at the final position of 20 mmHg; the lifting speed is 0.1-10 mmHg/min; in particular, the lifting speed is 0.5-5 mmHg/min.
Optionally, the pressure generating system 2 adopts a circulating fluctuation pressure mode, the pressure is set to be a circulating gravity water pressure value of continuous increase, continuous decrease and continuous increase, and the circulating fluctuation gravity water pressure value is realized by circularly lifting the water tank; the initial position of the circulation fluctuation pressure is 3mmHg, and after the pressure reaches 40mmHg, the pressure is reduced to 3mmHg, and the lifting speed is 0.1-10 mmHg/min.
The present invention is explained in detail below.
The system comprises a main control system 1, a pressure generating system 2, a sample fixing system 3, a pressure measuring system 4, and wires, pipelines and a box body which are connected and fixed with the subsystems. The electrical elements are connected through leads, and the pressure generating, transmitting and detecting components are connected through pipelines.
The main control system 1 comprises a computer host 11, a computer display 12 and pressure control and measurement software; the pressure value required to be measured is input by a detection person in the pressure control software, the main control system 1 transmits an instruction to the sliding controller 21 in the pressure generation system 2 to control the sliding part 23 to move to a required position, the pressure measurement system 4 measures the pressure fluctuation at the valve of the sample 33 of the glaucoma aqueous humor drainage device, and the pressure fluctuation is analyzed and processed through the measurement software.
The pressure generating system 2 includes a water tank 24, a slide rail 22, a slide member 23, and a slide controller 21; the sliding controller 21 is used for adjusting the sliding part 23 to move along the sliding rail 22, the sliding part 23 drives the water tank 24 fixed with the sliding part to move along the sliding rail 22, and the height change of the water tank 24 enables the water stored in the water tank to generate gravity water pressure which is transmitted to the sample fixing system 3 through the micro-pipeline switch 25; the slide controller 21 is connected to the host computer 11 in the main control system 1 through the connecting wire 7.
The sample fixing system 3 comprises a sample fixing base 31, a sample fixing clamp 32 and a glaucoma aqueous humor drainage device sample 33, the glaucoma aqueous humor drainage device sample 33 is connected with a three-way valve 5, and the three-way valve 5, a pressure measuring system 4 and a pressure micro-pipeline switch 25 are connected through a micro-pipeline 6; the glaucoma aqueous humor drainage device 33 is fixed up and down by the sample fixing base 31 and the sample fixing clip 32.
The pressure measurement system 4 comprises a pressure sensor probe 41, a sensor output switch power supply, a data acquisition instrument 42 and a connecting wire; the pressure sensor probe 41 is connected with the pressure generating system 2 and the drainage tube of the glaucoma aqueous humor drainage device 33 through the micro-pipeline 6 and the three-way valve 5, can sense the pressure fluctuation condition of the surface pipeline of the drainage valve of the glaucoma aqueous humor drainage device 33 in time, and the fluctuation pressure signal is converted and amplified into an electric signal through a sensor output switch power supply, then is collected by the data acquisition instrument 42 and transmitted to the main control system 1, and is displayed on the computer display 12 in a data curve form; the pressure sensor probe 41 is connected with the data acquisition instrument 42 through a connecting wire 7, and the data acquisition instrument 42 is connected with the computer host 11 of the main control system 1 through the connecting wire 7.
The detection method of the trace pressure fluctuation detection system in the embodiment is that the glaucoma aqueous humor drainage device sample 33 is fixed on the sample fixing base 31, the drainage tube of the glaucoma aqueous humor drainage device sample 33 is connected with the three-way valve 5, and the other two ends of the three-way valve 5 are respectively connected with the pressure generation system 2 and the pressure measurement system 4.
Adding 0.9% of normal saline into the water tank 24 to simulate aqueous humor and ensure that the water tank 24 is communicated with the atmosphere; next, the micro-tube 6 is checked for filling with saline and to try to eliminate bubble reduction errors in the tube. The sliding component 23 in the pressure generating system 2 is fixed at a certain height of the electric sliding rail 22, the pressure provided by the water tank 24 is calculated by ensuring that the pressure sensor probe 41 and the sample fixing base 31 are at the same height, the pressure value is measured by the pressure sensor probe 41, and the pressure value are calibrated to remove system errors caused by on-way resistance and the like.
Adjusting pressure control and measurement software in the main control system 1, closing a micro-pipeline switch 25 of the pressure generation system 2, setting a corresponding gravity water pressure value, realizing the set gravity water pressure by running a water tank 24 along a slide rail 22, opening the micro-pipeline switch 25 of the pressure generation system 2, detecting the surface pipeline pressure fluctuation condition of a drainage valve of a glaucoma aqueous humor drainage device sample 33 through a pressure measurement system 4, and realizing data reading, storage and graphic processing through a computer host 11 and a computer display 12 of the main control system 1.
After the detection is finished, the sample of the glaucoma aqueous humor drainage device is disassembled, and the normal saline in the water tank 24 and the micro-pipeline 6 is discharged, the equipment is checked and the machine is shut down.
A fixed mode detection method of a micro-pressure fluctuation detection system of a glaucoma aqueous humor drainage device comprises the steps of firstly, carrying out early preparation of the detection system, namely adding physiological saline, carrying out equipment calibration, connecting a sample of the glaucoma aqueous humor drainage device, and detecting the tightness of the glaucoma aqueous humor drainage device; after the early preparation work is finished, the pressure generation system adopts a fixed pressure mode, and the pressure is set to a series of specific gravity water pressure values; specially, the fixed pressure value is in the range of 3-40 mmHg; specially, the fixed pressure value is in the range of 5-20 mmHg; specifically, the fixed pressure values were 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20 mmHg; the pressure measurement system is used for detecting the pressure fluctuation condition of the pipeline on the surface of the drainage valve of the aqueous humor drainage device in the fixed pressure value mode, and the data reading, the data storage and the graph processing are realized through the main control system computer host and the computer display. And after the detection is finished, the drainage device is detached, the normal saline in the water tank and the pressure transmission pipeline is discharged, the equipment is checked, and the equipment is shut down.
Firstly, performing early preparation of a detection system, namely adding physiological saline, calibrating equipment, connecting a sample of the glaucoma aqueous humor drainage device, and detecting the tightness of the glaucoma aqueous humor drainage device; after the early preparation work is finished, the pressure generation system adopts a pressure increasing mode, the pressure is set as a continuously increased gravity water pressure value, and the continuously increased gravity water pressure value is realized through a continuously lifted water tank; continuously increasing pressure at initial position of 3mmHg, ending position of 40mmHg, and lifting speed of 0.1-10 mmHg/min; specially, the initial position of continuously increasing pressure is 5mmHg, the final position is 20mmHg, and the lifting speed is 0.5-5 mmHg/min; the pressure measurement system is used for detecting the pressure fluctuation condition of the pipeline on the surface of the drainage valve of the aqueous humor drainage device in the mode of continuously increasing the pressure value, and the data reading, the storage and the graphic processing are realized through the computer host and the computer display of the main control system. And (4) after the detection is finished, disassembling the sample of the glaucoma aqueous humor drainage device, discharging the normal saline in the water tank and the pressure transmission pipeline, checking the equipment and shutting down the equipment.
A method for detecting the circulating fluctuation pressure mode of a micro-pressure fluctuation detection system of a glaucoma aqueous humor drainage device comprises the steps of firstly, carrying out early preparation of the detection system, namely adding physiological saline, carrying out equipment calibration, connecting a sample of the glaucoma aqueous humor drainage device, and detecting the tightness of the sample; after the early preparation work is finished, the pressure generation system adopts a circulating fluctuation pressure mode, the pressure is set to be a gravity water pressure value of continuous increase, continuous decrease and continuous increase, and the gravity water pressure value of the circulating fluctuation is realized by a circulating lifting water tank; the initial position of the circulating fluctuation pressure is 3mmHg, the pressure is reduced to 3mmHg after reaching 40mmHg, and the lifting speed is 0.1-10 mmHg/min; specially, the initial position of continuously increasing the pressure is 5mmHg, the pressure is reduced to 5mmHg after reaching 20mmHg, the final position is 20mmHg, and the lifting speed is 0.5-5 mmHg/min; the pressure measurement system is used for detecting the pressure fluctuation condition of the pipeline on the surface of the drainage valve of the aqueous humor drainage device in the circulating fluctuation pressure mode, and the data reading, the storage and the graphic processing are realized through the computer host and the computer display of the main control system. And (4) after the detection is finished, disassembling the sample of the glaucoma aqueous humor drainage device, discharging the normal saline in the water tank and the pressure transmission pipeline, checking the equipment and shutting down the equipment.
In conclusion, the invention provides a trace pressure fluctuation detection system and a detection method, which are used for detecting the pressure fluctuation of the pipeline on the surface of the drainage valve of the glaucoma aqueous humor drainage device, accurately detecting the pressure of the pipeline with the special microenvironment for opening and closing the valve, providing a technical platform for the industrial development of a novel aqueous humor drainage device, and being used for performance detection and quality evaluation. The micro-pressure fluctuation detection system of the glaucoma aqueous humor drainage device has the advantages of simple structure, reliable detection method and high validity of detection results.
While the invention has been described with reference to a preferred embodiment, it will be understood by those skilled in the art that various changes in form and detail may be made therein without departing from the spirit and scope of the invention.
Claims (9)
1. A micro pressure fluctuation detection system is characterized by comprising a main control system, a pressure generation system connected with the main control system through a connecting lead, a sample fixing system connected with the pressure generation system through a micro pipeline, and a pressure measurement system connected with the sample fixing system through a micro pipeline, wherein the pressure measurement system is connected with the main control system through a connecting lead; the pressure measuring system senses the pressure fluctuation condition in the sample fixing system in real time, converts and amplifies the pressure fluctuation condition into an electric signal and transmits the electric signal to the main control system, and the main control system displays the electric signal in a data curve form.
2. The trace pressure fluctuation detection system of claim 1, wherein the master control system comprises a computer host, a computer display, and pressure control and measurement software embedded in the computer host.
3. The trace pressure fluctuation detection system according to claim 2, wherein the pressure generation system comprises a sliding controller, a motor-driven sliding rail, a sliding part slidably disposed on the motor-driven sliding rail, a water tank fixed on the sliding part, and a micro-pipe switch, and the sliding controller is connected to the host computer through a connecting wire.
4. The system of claim 3, wherein the sample fixing system comprises a fixing base, a sample fixing head mounted on the fixing base, and a glaucoma aqueous humor drainage device fixed on the fixing base through the sample fixing head, and the glaucoma aqueous humor drainage valve device sample is connected to the pressure pipeline interface of the water tank through a three-way valve and the micro pipeline.
5. The micro pressure fluctuation detection system of claim 4, wherein the pressure measurement system comprises a pressure sensor probe, a data acquisition instrument and a sensor output switching power supply, the pressure sensor probe is connected with the glaucoma aqueous humor drainage device through the micro pipeline and the three-way valve, and the data acquisition instrument is connected with the computer host through a connecting wire.
6. A detection method of a trace pressure fluctuation detection system is characterized by comprising the following steps:
adjusting pressure control and measurement software in the main control system, closing a micro-pipeline switch of the pressure generation system, setting a corresponding gravity water pressure value, realizing the set gravity water pressure by the operation of the water tank along the sliding rail, opening the micro-pipeline switch of the pressure generation system, detecting the pressure fluctuation condition of the pipeline on the surface of the drainage valve of the glaucoma aqueous humor drainage device by the pressure measurement system, and realizing data reading, storage and graphic processing by a computer host and a computer display of the main control system.
7. The method of claim 6, wherein the pressure generating system is in a fixed pressure mode, and the pressure is set to a specific gravity water pressure value; the fixed pressure value is in the range of 3-40 mmHg; the fixed pressure values were 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19 and 20 mmHg.
8. The method of claim 6, wherein the pressure generating system is in an increasing pressure mode, and the pressure is set to a continuously increasing gravitational water pressure value, and the continuously increasing gravitational water pressure value is realized by the continuously raised water tank; continuously increasing the pressure to 3mmHg at the initial position and 40mmHg at the final position; the lifting speed is 0.1-10 mmHg/min.
9. The method of claim 6, wherein the pressure generating system is in a cyclic fluctuation pressure mode, the pressure is set to a continuous increase-continuous decrease-continuous increase cyclic gravity water pressure value, and the cyclic fluctuation gravity water pressure value is realized by cyclically elevating the water tank; the initial position of the circulation fluctuation pressure is 3mmHg, and after the pressure reaches 40mmHg, the pressure is reduced to 3mmHg, and the lifting speed is 0.1-10 mmHg/min.
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