CN113951849B - Biological signal acquisition circuit and mouse - Google Patents

Biological signal acquisition circuit and mouse Download PDF

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Publication number
CN113951849B
CN113951849B CN202111290571.XA CN202111290571A CN113951849B CN 113951849 B CN113951849 B CN 113951849B CN 202111290571 A CN202111290571 A CN 202111290571A CN 113951849 B CN113951849 B CN 113951849B
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analog
sensor
channel
output
sensor unit
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CN113951849A (en
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金智明
刘红超
李少平
张凤宇
董旸
王洁
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China Resources Microelectronics Holding Co ltd
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China Resources Microelectronics Holding Co ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/0205Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/318Heart-related electrical modalities, e.g. electrocardiography [ECG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6887Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient mounted on external non-worn devices, e.g. non-medical devices
    • A61B5/6897Computer input devices, e.g. mice or keyboards
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7235Details of waveform analysis
    • A61B5/7264Classification of physiological signals or data, e.g. using neural networks, statistical classifiers, expert systems or fuzzy systems
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F3/00Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
    • G06F3/01Input arrangements or combined input and output arrangements for interaction between user and computer
    • G06F3/03Arrangements for converting the position or the displacement of a member into a coded form
    • G06F3/033Pointing devices displaced or positioned by the user, e.g. mice, trackballs, pens or joysticks; Accessories therefor
    • G06F3/0354Pointing devices displaced or positioned by the user, e.g. mice, trackballs, pens or joysticks; Accessories therefor with detection of 2D relative movements between the device, or an operating part thereof, and a plane or surface, e.g. 2D mice, trackballs, pens or pucks
    • G06F3/03543Mice or pucks
    • GPHYSICS
    • G06COMPUTING; CALCULATING OR COUNTING
    • G06FELECTRIC DIGITAL DATA PROCESSING
    • G06F3/00Input arrangements for transferring data to be processed into a form capable of being handled by the computer; Output arrangements for transferring data from processing unit to output unit, e.g. interface arrangements
    • G06F3/16Sound input; Sound output
    • G06F3/167Audio in a user interface, e.g. using voice commands for navigating, audio feedback

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medical Informatics (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Surgery (AREA)
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  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Molecular Biology (AREA)
  • Signal Processing (AREA)
  • Physiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Artificial Intelligence (AREA)
  • Theoretical Computer Science (AREA)
  • Computer Vision & Pattern Recognition (AREA)
  • Psychiatry (AREA)
  • Cardiology (AREA)
  • Human Computer Interaction (AREA)
  • General Physics & Mathematics (AREA)
  • Evolutionary Computation (AREA)
  • Fuzzy Systems (AREA)
  • Mathematical Physics (AREA)
  • Pulmonology (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Optics & Photonics (AREA)
  • Multimedia (AREA)
  • Audiology, Speech & Language Pathology (AREA)
  • Power Engineering (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)

Abstract

The invention relates to a biological signal acquisition circuit and a mouse. The biological signal acquisition circuit includes: at least one sensor unit for acquiring corresponding biological signals; the level matching circuit is provided with level adjustment channels with the same number as the sensor units, the input end of each channel of level adjustment channel is connected with the output end of one sensor unit, and the level matching circuit is used for uniformly processing the voltage of the analog signals output by each sensor unit and then outputting the analog signals through the output end of the level adjustment channel; the multichannel analog switching circuit is used for carrying out time-sharing gating on each output end and outputting a gated analog signal through the output end; and the analog-to-digital converter is used for performing analog-to-digital conversion on the analog signals output by the output end of the multi-channel analog switching circuit. The invention can remove the delay caused by different ADC sampling parameters when different sensors acquire parameters.

Description

Biological signal acquisition circuit and mouse
Technical Field
The invention relates to signal acquisition, in particular to a biological signal acquisition circuit and a mouse.
Background
With the development of the intelligent health industry and the severe situation of pandemic in recent years, the public has increasingly increased the monitoring demands for vital sign parameters of human bodies, and the consumer market demands for wearable health products have increasingly increased. The vital sign parameters of the human body mainly focused at the present stage mainly comprise heart rate, blood oxygen saturation, blood pressure, body temperature and the like. Photoplethysmogram (PPG) and Electrocardiography (ECG) are theoretical basis for measuring human body physical parameters, PPG is a monitoring means for detecting blood volume changes in human body tissue by means of photoelectric means, mainly applied to monitoring of blood oxygen saturation; ECG is to capture the weak electrocardiosignal of human body by the electric charge quantity of the contact skin through the electrode, detect the electric potential transmission of the heart, is used for heart rate monitoring; the blood pressure parameters need to be combined with PPG and ECG signals, and the signals are needed to be synchronized through a processing circuit and then are obtained through complex algorithm calculation; body temperature parameters can also be obtained by the sensor.
For the health equipment integrated with the sensors, the technical scheme is that the discrete sensors are integrated, digital interfaces of the sensor modules are respectively connected into a microprocessor, calculation is carried out through an algorithm, and corresponding parameters are finally output for background processing or display. However, this scheme can only acquire the acquired data of one sensor at the same time, and requires separate power management. Since the signals are accessed to the microprocessor through the digital interface, the synchronization delay of the data between the different channels is unavoidable.
Disclosure of Invention
Based on this, it is necessary to provide a low-delay biological signal acquisition circuit.
A biological signal acquisition circuit comprising: at least one sensor unit for acquiring corresponding biological signals; the level matching circuit is provided with level adjustment channels with the same number as the sensor units, the input end of each channel of level adjustment channel is connected with the output end of one sensor unit, and the level matching circuit is used for uniformly processing the voltage of the analog signals output by each sensor unit and then outputting the analog signals through the output end of the level adjustment channel; the multi-channel analog switching circuit is connected with each output end, and is used for carrying out time-sharing gating on each output end and outputting a gated analog signal through the output end of the multi-channel analog switching circuit; and the analog-to-digital converter is connected with the output end of the multi-channel analog switching circuit and is used for performing analog-to-digital conversion on the analog signal output by the output end of the multi-channel analog switching circuit.
According to the biological signal acquisition circuit, different sensor units can perform level matching on acquired analog signals through the level matching circuit, and the analog-to-digital converter can acquire data of the sensor units one by one through the multi-channel analog switching circuit and perform synchronous scanning. Because different sensor units share one analog-to-digital converter, different sensor signals can adopt the same ADC sampling rate and sampling interval and the same ADC parameters, thereby eliminating the delay caused by different ADC sampling parameters when different sensors acquire parameters.
In one embodiment, each channel of the level adjustment channel includes an NMOS transistor, a source of the NMOS transistor is used as an input end of the level adjustment channel, a drain of the NMOS transistor is used as an output end of the level adjustment channel, a gate and a source of the NMOS transistor are connected to a supply voltage end, and a drain of the NMOS transistor is connected to a working voltage end.
In one embodiment, the power supply voltage terminal of each channel of the level adjustment channel is a power supply voltage terminal of a corresponding sensor unit.
In one embodiment, a first resistor is connected between the power supply voltage terminal and the source electrode, and a second resistor is connected between the working voltage terminal and the drain electrode.
In one embodiment, the multi-path analog switching circuit includes an LTC6091 chip, a first non-inverting input terminal and a second non-inverting input terminal of the LTC6091 chip are respectively connected to an output terminal of the level matching circuit, a first inverting input terminal and a second inverting input terminal of the LTC6091 chip are grounded, a first output disable pin of the LTC6091 chip is used for receiving a chip select signal, the chip select signal is connected to a second output disable pin of the LTC6091 chip through an inverter, and a first output terminal and a second output terminal of the LTC6091 chip are connected to an output terminal of the multi-path analog switching circuit.
In one embodiment, the at least one sensor unit comprises an ECG sensor unit.
In one embodiment, the at least one sensor unit comprises a PPG sensor unit.
In one embodiment, the at least one sensor unit comprises a temperature sensor unit.
It is also necessary to provide a mouse.
A mouse comprising a mouse housing and the biological signal acquisition circuit of any of the foregoing embodiments, the mouse having a side surface disposed on the mouse housing, the sensor module comprising each of the sensor units.
In one embodiment, the sensor module is integrated in a chip.
In one embodiment, the mouse further comprises a movable finger support that extends outwardly from a position where the mouse housing is at the bottom of the sensor module when moved to a first position, the finger support covering the sensor module when moved to a second position.
In one embodiment, the mouse further comprises a hinge arranged at a position of the mouse shell at the bottom of the sensor module, and the finger support piece is rotatably connected with the mouse shell through the hinge.
In one embodiment, the sensor module comprises a pressure sensor, the mouse further comprises a control module and a voice prompt module, and the control module is electrically connected with the pressure sensor and the voice prompt module; the control module is used for controlling the voice prompt module to prompt a user to provide proper pressure according to the pressure signal detected by the pressure sensor.
In one embodiment, the control module is further configured to prompt the user to press for a sufficient time.
In one embodiment, the system further comprises a signal processing circuit, which is used for performing noise reduction filtering processing on the pulse signals acquired by the PPG sensor and the electrocardiosignals acquired by the ECG sensor; the control module is also used for extracting the characteristics of the signals output by the signal processing circuit to obtain characteristic vectors, and inputting the characteristic vectors into the neural network model to obtain blood pressure measured values.
Drawings
For a better description and illustration of embodiments and/or examples of those inventions disclosed herein, reference may be made to one or more of the accompanying drawings. Additional details or examples used to describe the drawings should not be construed as limiting the scope of the disclosed invention, the presently described embodiments and/or examples, and any of the presently understood modes of carrying out the invention.
FIG. 1 is a left side view of a mouse with blood pressure measurement function in one embodiment;
FIG. 2 is a schematic diagram of a sensor module integrating sensors in one embodiment;
FIG. 3 is a flow chart of a mouse measuring blood pressure in one embodiment;
FIG. 4 is a flow chart of a method of acquiring and processing biological signals in one embodiment;
FIG. 5 is a circuit block diagram of an exemplary health device incorporating multiple sensors;
FIG. 6 is a circuit block diagram of a biological signal acquisition circuit in one embodiment;
FIG. 7 is a schematic diagram of a biological signal acquisition circuit in one embodiment;
FIG. 8 is a schematic circuit diagram of one channel level adjustment channel of a level matching circuit in one embodiment;
fig. 9 is a circuit schematic of a multi-path analog switching circuit in one embodiment.
Detailed Description
In order that the invention may be readily understood, a more complete description of the invention will be rendered by reference to the appended drawings. Preferred embodiments of the present invention are shown in the drawings. This invention may, however, be embodied in many different forms and should not be construed as limited to the embodiments set forth herein. Rather, these embodiments are provided so that this disclosure will be thorough and complete.
Unless defined otherwise, all technical and scientific terms used herein have the same meaning as commonly understood by one of ordinary skill in the art to which this invention belongs. The terminology used herein in the description of the invention is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. The term "and/or" as used herein includes any and all combinations of one or more of the associated listed items.
It will be understood that when an element or layer is referred to as being "on," "adjacent," "connected to," or "coupled to" another element or layer, it can be directly on, adjacent, connected, or coupled to the other element or layer, or intervening elements or layers may be present. In contrast, when an element is referred to as being "directly on," "directly adjacent to," "directly connected to," or "directly coupled to" another element or layer, there are no intervening elements or layers present. It will be understood that, although the terms first, second, third, etc. may be used herein to describe various elements, components, regions, layers and/or sections, these elements, components, regions, layers and/or sections should not be limited by these terms. These terms are only used to distinguish one element, component, region, layer or section from another element, component, region, layer or section. Thus, a first element, component, region, layer or section discussed below could be termed a second element, component, region, layer or section without departing from the teachings of the present invention.
Spatially relative terms, such as "under," "below," "beneath," "under," "above," "over," and the like, may be used herein for ease of description to describe one element or feature's relationship to another element or feature as illustrated in the figures. It will be understood that the spatially relative terms are intended to encompass different orientations of the device in use and operation in addition to the orientation depicted in the figures. For example, if the device in the figures is turned over, elements or features described as "under" or "beneath" other elements would then be oriented "on" the other elements or features. Thus, the exemplary terms "below" and "under" may include both an upper and a lower orientation. The device may be otherwise oriented (rotated 90 degrees or other orientations) and the spatially relative descriptors used herein interpreted accordingly.
The terminology used herein is for the purpose of describing particular embodiments only and is not intended to be limiting of the invention. As used herein, the singular forms "a", "an" and "the" are intended to include the plural forms as well, unless the context clearly indicates otherwise. It will be further understood that the terms "comprises" and/or "comprising," when used in this specification, specify the presence of stated features, integers, steps, operations, elements, and/or components, but do not preclude the presence or addition of one or more other features, integers, steps, operations, elements, components, and/or groups thereof. As used herein, the term "and/or" includes any and all combinations of the associated listed items.
Referring to fig. 5, an exemplary health device integrated with multiple sensors integrates discrete sensors, and digital interfaces of the sensor modules are respectively connected to a Microprocessor (MCU), calculated through an algorithm, and finally output corresponding parameters for background processing/display. However, the scheme can only acquire the acquired data of one sensor at the same time, needs independent power management, and has the advantages of higher power consumption, poor expansibility, low integration level and no contribution to the requirements of portable wearable equipment such as battery power supply. Because the signals are accessed into the microprocessor through the digital interface, the synchronous delay of the data among different channels cannot be avoided, the delay of the signals brings high algorithm requirements for the fusion of the data of multiple sensors, and the requirements for the real-time data analysis capability of the processor are high, so that the realization difficulty is high, and the popularization and the application of the technology are not facilitated.
The application provides a biological signal acquisition circuit, can solve the fusion and the synchronous problem of multiple acquisition sensor direct data, reduce signal delay. Fig. 6 is a circuit block diagram of a biological signal acquisition circuit according to an embodiment of the present application, including a level matching circuit 120, a multi-channel analog switching circuit 130, and an analog-to-digital converter (ADC) 140, and further including at least one sensor unit, where the sensor types of the different sensor units are different, for example, the biological signal acquisition circuit may include an ECG sensor, a PPG sensor, a pressure sensor, a temperature sensor, and peripheral circuits corresponding to the sensors. In one embodiment of the present application, the signal link front end (i.e., the sensor unit) built by the discrete components may be replaced by some integrated analog ICs, so as to obtain higher acquisition accuracy.
The level matching circuit 120 has level adjustment channels equal to the number of sensor units, for example, for the embodiment shown in fig. 6 having three sensor units, the level matching circuit 120 has three level adjustment channels connected to the output terminals of the respective sensor units in one-to-one correspondence. The level matching circuit 120 is configured to perform voltage unification on analog signals output by each sensor unit, and output the analog signals through an output end of a level adjustment channel, where sensors of different level systems may perform level matching through the level matching circuit 120.
The multi-path analog switching circuit 130 is connected to the output terminal of each level adjustment channel. The multi-path analog switching circuit 130 is configured to perform time-division gating on each output terminal of the level adjustment channel, and output a gated analog signal through the output terminal of the multi-path analog switching circuit 130. More sensors can be easily expanded using the multi-path analog switching circuit 130, and expansibility is greatly improved.
The analog-to-digital converter 140 is connected to the output terminal of the multi-channel analog switching circuit 130, and is configured to perform analog-to-digital conversion on the analog signal output by the output terminal of the multi-channel analog switching circuit 130. The analog-to-digital converter 140 outputs the digital signal obtained by the analog-to-digital conversion to a processor (e.g., MCU) for calculation processing. After the signals transmitted by the level adjustment channels pass through the multi-path analog switching circuit 130, the analog-to-digital converter 140 can perform synchronous scanning and collect sensor data one by one.
In the biological signal acquisition circuit, different sensor units can perform level matching on the acquired analog signals through the level matching circuit 120, and the analog-to-digital converter 140 can acquire data of the sensor units one by one through the multi-path analog switching circuit 130 and perform synchronous scanning. In the traditional scheme, a single sensor acquisition channel is matched with a corresponding ADC channel, parameters are not fixed, and acquisition delay and precision loss exist. The sensor units which are different in application share the analog-to-digital converter, so that the same ADC sampling rate, sampling interval and the same ADC parameters can be adopted for different sensor signals, delay caused by different ADC sampling parameters when different sensors collect parameters is eliminated, multi-sensor data are effectively subjected to fusion synchronous processing, the collection sensitivity is improved, the ultra-low power consumption MCU is integrated inside, the output of a unified digital interface is realized, the algorithm difficulty is reduced, the power consumption of an overall scheme is reduced, the integration level of the overall scheme can be improved, and the integrated use of various products is facilitated.
In one embodiment of the present application, the biological signal acquisition circuit further includes a signal processing circuit for performing noise reduction, filtering, and the like on the signal output by the sensor.
Fig. 7 is a schematic diagram of a bio-signal acquisition circuit in an embodiment that integrates an ECG sensor, a PPG sensor, and a temperature sensor. Fig. 8 is a schematic circuit diagram of one channel level adjustment channel of the level matching circuit 120 in one embodiment. Each path of level adjustment channel comprises an NMOS tube, the source electrode of the NMOS tube is used as the input end of the level adjustment channel, the drain electrode of the NMOS tube is used as the output end of the level adjustment channel, the grid electrode and the source electrode of the NMOS tube are connected with a power supply voltage end VCC, and the drain electrode of the NMOS tube is connected with a working voltage end VDD. In the embodiment shown in fig. 8, a resistor is connected between the power supply voltage terminal VCC and the gate of the NMOS transistor, and a resistor is also connected between the power supply voltage terminal VCC and the source of the NMOS transistor, and a resistor is connected between the operating voltage terminal VDD and the drain of the NMOS transistor. The resistance between the source electrode and the drain electrode of the NMOS tube is used for testing in a debugging stage, and is not welded in a factory product.
In one embodiment of the present application, the supply voltage terminal VCC of the level adjustment channel connection is the supply voltage terminal of the corresponding sensor unit. For example, for a level adjustment channel connected to an ECG circuit, the supply voltage terminal VCC is the supply voltage terminal VCC of the ECG circuit.
In one embodiment of the present application, the multi-path analog switching circuit 130 includes an LTC6091 chip. The first non-inverting input terminal and the second non-inverting input terminal of the LTC6091 chip are respectively connected to an output terminal of the level matching circuit 120 (for example, the first non-inverting input terminal is connected to an output terminal of a level adjustment channel corresponding to the ECG sensor, and the second non-inverting input terminal is connected to an output terminal of a level adjustment channel corresponding to the PPG sensor), and the first inverting input terminal and the second inverting input terminal of the LTC6091 chip are grounded. The first output disable pin OD of the LTC6091 chip is for receiving a chip SELECT signal SELECT that is connected to the second output disable pin OD of the LTC6091 chip through an inverter. The first output terminal and the second output terminal of the LTC6091 chip are connected to the output terminal of the multi-path analog switching circuit 130.
Fig. 9 is a schematic circuit diagram of a multi-path analog switching circuit 130 in one embodiment. The input signal is input from the inverting input end and the non-inverting input end of the operational amplifier, the resistor and the internal diode of the operational amplifier form clamping to the input signal, the select NOT signal is a select chip select signal, and the current is output from the MUX OUT and is input to the non-inverting input end of the other channel through the feedback resistor of the disabled operational amplifier, so that signal switching of different analog signal channels is realized. For the case where the number of paths of the multi-path analog switching circuit 130 is greater than two, the multi-path analog switching circuit 130 may employ more than one LTC6091 chip. The multi-path analog switching circuit 130 may also be constructed using other MUX (data selector) chips known in the art.
The biological signal acquisition circuit can be applied to human vital sign parameter monitoring equipment integrated with various sensors. The application correspondingly provides a mouse, which comprises a mouse shell, and further comprises the biological signal acquisition circuit in any embodiment, wherein each sensor unit of the biological signal acquisition circuit is integrated in a sensor module and is arranged on the side surface of the mouse shell.
Furthermore, the application provides a novel intelligent healthy mouse for measuring blood pressure of a business person, and the sensor module is arranged on the side face of the mouse, so that the blood pressure condition of the business person can be monitored in real time. However, there is a problem in measuring blood pressure by a mouse, and it is necessary to provide a constant pressure for blood pressure monitoring to obtain an accurate value.
Fig. 1 is a left side view of a mouse having a blood pressure measurement function in one embodiment. The mouse includes a mouse housing 10, a sensor module 20, and a finger support 30. The sensor module 20 is provided at a side of the mouse housing 10, and the sensor module 20 is used to acquire a blood pressure-related signal when in contact with a finger. In one embodiment of the present application, the sensor module 20 is positioned at the desired thumb placement position on the left side of the mouse housing 10. The finger support 30 is of a movable structure, and when blood pressure detection is required, the finger support 30 is adjusted to a position extending transversely from the bottom of the sensor module 20 to the outer side of the mouse housing 10, and the thumb is naturally placed on the finger support 30, so that continuous and stable pressure can be provided by the finger. When blood pressure is not being detected, the finger support 30 can be adjusted to a position that covers the sensor module 20, thereby protecting the sensor module 20.
The mouse with blood pressure measuring function provides a relatively stable support for the finger through the finger support 30, which is beneficial to providing continuous and stable pressure for the sensor module 20, thereby improving the accuracy of the acquired blood pressure related signals. When it is not necessary to measure blood pressure, the finger support 30 can cover the sensor module 20, avoiding the sensor module 20 from being stained/aged by the external environment or fingers, etc. The mouse is used as an office auxiliary tool necessary for business persons, is necessary equipment for business trips, and is small in size, light in weight and convenient to carry. The module for detecting the blood pressure is embedded into the mouse, so that the blood pressure can be effectively detected through the mouse.
The level matching circuit, the multichannel analog switching circuit and the analog-to-digital converter of the biological signal acquisition circuit and the structure of a common mouse are arranged inside the mouse coated by the mouse shell 10 so as to realize the mouse function, and an acceleration sensor, a Bluetooth module, a power supply and the like can be integrated. The acceleration sensor improves the sensitivity of the mouse, and the Bluetooth module is used for realizing connection of the mouse and other Bluetooth devices provided with the Bluetooth module. The power supply can be a battery, so that the mouse can be used as an independent blood pressure measuring device without being connected with a computer.
In one embodiment of the present application, the finger support 30 is rotatably coupled to the mouse housing 10. Further, the finger support 30 may be pivotally connected to the mouse housing 10 by a hinge.
In one embodiment of the present application, the sensor module 20 includes a pressure sensor, and the mouse further includes a control module and a voice prompt module. The control module is electrically connected with the pressure sensor and the voice prompt module, and is used for controlling the voice prompt module to prompt a user to provide proper pressure according to the pressure signal detected by the pressure sensor and prompting the user to press for enough time. Specifically, the voice prompt content may include a pressing position, a pressing force, a pressing time, and the like, so as to ensure accuracy of the measurement result. The control module may be an MCU.
In one embodiment of the present application, the voice prompt module may prompt the user to increase the pressing force when the pressure value detected by the pressure sensor is less than the first threshold value, and may prompt the user to decrease the pressing force when the pressure value detected by the pressure sensor is greater than the second threshold value.
In one embodiment of the present application, the control module may calculate which position of the finger presses on the sensor module 20 according to the pressure signal detected by the pressure sensor, and prompt the user to move the finger to the correct position through the voice prompt module when the pressing position is inaccurate.
In one embodiment of the present application, the voice prompt module is further configured to prompt the user to continue to press the sensor module 20 when the time to press the pressure sensor has not reached the preset duration. In one embodiment of the present application, the voice prompt module is further configured to prompt the user to stop pressing when the time of pressing the sensor module 20 reaches a preset duration.
The finger support 30 and the voice prompt module ensure the stability of the finger pressing sensor module 20 in two aspects, so that the blood pressure result is more accurate and reliable.
FIG. 2 is a schematic diagram of sensor module 20 integrating sensors in one embodiment. In the embodiment shown in fig. 2, sensor module 20 includes a pressure sensor 22, a PPG sensor 24, an ECG sensor 26, and a temperature sensor 28.PPG sensor 24, a photoplethysmograph (photoplethysmograph) sensor, uses a photosensor to detect differences in reflected light intensity after absorption by human blood and tissue, and to trace changes in the volume of the blood vessel over the cardiac cycle. The PPG sensor 24 is mainly used for acquiring and reading pulse waves. The ECG sensor 26, i.e., an Electrocardiogram (ECG) sensor, is mainly used for receiving and processing an electrocardiographic signal. The temperature sensor 28 is used for measuring temperature, and can detect the temperature of the human body for reference by a user. In one embodiment of the present application, the temperature sensor 28 is used to test the finger temperature of the compression sensor module 20. In other embodiments, the temperature sensor 28 may also be an infrared temperature measurement module, which can measure the real-time temperature of the common body temperature measurement parts such as the wrist and forehead of the user, and assist the user in judging whether fever occurs.
Referring to fig. 2, the sensor module 20 is a chip integrated with a plurality of sensor devices, and forms a special multi-sensor module, and various sensor functions are integrated in one chip, so that the functions of various sensors can complement each other and are matched with each other. And the chip is only the size of the thumb nail cover, can be easily arranged in the mouse without affecting the normal use of the mouse, and is very convenient to install. Meanwhile, the chip can rapidly calculate and process the acquired data, so that a detection result can be obtained in the shortest time, and the blood pressure value can be output, thereby being very convenient and rapid.
In one embodiment of the present application, the mouse is further configured with a signal processing circuit for performing noise reduction filtering processing on the pulse signal acquired by the PPG sensor 24 and the electrocardiograph signal acquired by the ECG sensor 26. The signal processing circuitry may be integrated in the sensor module 20 or in a chip inside the mouse.
In an embodiment of the present application, the control module is further configured to perform feature extraction on a signal output by the signal processing circuit, obtain a feature vector, and input the feature vector into the neural network model to obtain a blood pressure measurement value.
In one embodiment of the present application, the mouse housing 10 is further provided with a display module for displaying the blood pressure measurement value. The display module may be a liquid crystal display module or the like. In other embodiments, the blood pressure measurement may also be voice output by the voice prompt module. In one embodiment of the present application, an electrocardiogram may be obtained by the ECG sensor 26 and the display module may also display the electrocardiogram.
Referring to fig. 3, the mouse of the present application measures blood pressure as follows:
s310, the user' S finger contacts the sensor module.
The user adjusts the finger support 30 of the mouse to a position extending laterally from the bottom of the sensor module 20 to the outside of the mouse housing 10, and the thumb naturally rests on the finger support 30, the finger support 30 supporting the thumb, and the user presses the sensor module 20 with a proper force.
S320, the voice prompt module guides the user to execute the action.
The voice prompt may include a pressing position, a pressing force, a pressing time, etc., thereby ensuring accuracy of the measurement result.
In one embodiment of the present application, the voice prompt module may prompt the user to increase the pressing force when the pressure value detected by the pressure sensor is less than the first threshold value, and may prompt the user to decrease the pressing force when the pressure value detected by the pressure sensor is greater than the second threshold value.
In one embodiment of the present application, the voice prompt module prompts the user to move the finger to the correct position when the pressed position is inaccurate.
In one embodiment of the present application, the voice prompt module prompts the user to continue pressing the sensor module 20 when the press does not reach the preset duration. In one embodiment of the present application, the voice prompt module prompts the user that the press may be stopped when the time to press the sensor module 20 reaches a preset duration.
S330, the sensor module collects signals.
When the finger presses the sensor module 20, the sensor module 20 acquires the electrocardiographic and pulse wave signals synchronously through the ECG sensor 26 and the PPG sensor 24.
S340, signal processing.
And (3) performing noise reduction filtering processing on the electrocardio and pulse wave signals acquired in the step S330.
S350, extracting signal characteristics.
Based on the electrocardiograph and pulse wave signals obtained after the processing in step S340, pulse wave conduction time is extracted from each heartbeat cycle to form a feature vector.
S360, calculating the blood pressure value.
And (3) inputting the feature vector obtained in the step (S350) into a trained neural network model to obtain a measured value of blood pressure, namely a pressure value.
S370, outputting the blood pressure value.
In one embodiment of the present application, the blood pressure measurement value obtained in step S360 may be displayed by the display module. In other embodiments, the blood pressure measurement may also be voice output by the voice prompt module.
The application correspondingly provides a method for acquiring and processing biological signals. FIG. 4 is a flowchart of a method for acquiring and processing biological signals according to an embodiment, comprising the following steps:
s410, providing a finger support platform through a finger support on the side of the mouse.
The mouse includes a mouse housing 10, a sensor module 20, and a finger support 30. The finger support 30 is a movable structure, and when blood pressure detection is required, the finger support 30 is adjusted to a position extending transversely from the bottom of the sensor module 20 to the outer side of the mouse housing 10, and as a finger support platform, the thumb is naturally placed on the finger support 30, so that the continuous and stable pressure can be provided by the finger. When blood pressure is not being detected, the finger support 30 can be adjusted to a position that covers the sensor module 20, thereby protecting the sensor module 20.
For the scheme of detecting blood pressure by using a mouse, the position is not fixed due to unstable pressing force of a user, so that a larger deviation of the result is easy to occur. The scheme of this application has added finger support 30, can overturn finger support 30 when not carrying out blood pressure measurement and protect sensor module 20, can pull down finger support 30 as the platform of support finger when needing to carry out blood pressure measurement, and is very convenient.
S420, acquiring a blood pressure related signal through a sensor module arranged on the side face of the mouse.
In one embodiment of the present application, the blood pressure related signals include electrocardiographic and/or pulse wave signals. In one embodiment of the present application, the sensor module 20 includes a PPG sensor 24 and an ECG sensor 26. The PPG sensor 24 is mainly used for acquiring and reading pulse waves. The ECG sensor 26 is mainly used for receiving and processing the electrocardiographic signals. In one embodiment of the present application, the sensor module 20 further includes a pressure sensor.
And S430, prompting a user to provide proper pressure according to the pressure signal acquired by the pressure sensor.
The voice prompt may include a pressing position, a pressing force, a pressing time, etc., thereby ensuring accuracy of the measurement result.
In one embodiment of the present application, the user may be prompted to increase the pressing force when the pressure value detected by the pressure sensor is less than the first threshold value, and may be prompted to decrease the pressing force when the pressure value detected by the pressure sensor is greater than the second threshold value.
In one embodiment of the present application, the user is prompted to move the finger to the correct position when the pressed position is inaccurate.
In one embodiment of the present application, the user is prompted to continue pressing the sensor module 20 when the press does not reach a preset duration. In one embodiment of the present application, the user is prompted to stop pressing when the time to press the sensor module 20 reaches a preset duration.
S440, processing the blood pressure related signals.
The blood pressure-related signal obtained in step S420 is processed to obtain a blood pressure measurement value.
According to the biological signal acquisition and processing method, the finger support piece is used for providing a relatively stable support for the finger, so that the finger is facilitated to provide continuous and stable pressure for the sensor module, and a user is prompted to provide proper pressure according to the pressure value acquired by the pressure sensor, so that the accuracy of acquired blood pressure related signals is improved.
In one embodiment of the present application, the method for acquiring and processing a biological signal further comprises the steps of:
s450, noise reduction and filtering processing is carried out on the blood pressure related signals.
And (3) performing noise reduction filtering processing on the pulse signals and the electrocardiosignals obtained in the step S420.
S460, carrying out feature extraction on the pulse signals and the electrocardiosignals after noise reduction and filtering processing to obtain feature vectors.
Based on the electrocardiograph and pulse wave signals obtained after the processing in step S450, pulse wave conduction time is extracted from each heartbeat cycle, and a feature vector is formed.
S460, inputting the feature vector into the neural network model to obtain a blood pressure measured value.
It should be understood that, although the steps in the flowcharts of this application are shown in order as indicated by the arrows, these steps are not necessarily performed in order as indicated by the arrows. The steps are not strictly limited to the order of execution unless explicitly recited herein, and the steps may be executed in other orders. Moreover, at least a portion of the steps in the flowcharts of this application may include a plurality of steps or a plurality of stages, which are not necessarily performed at the same time, but may be performed at different times, and the order of the execution of the steps or stages is not necessarily sequential, but may be performed in turn or alternately with at least a portion of the steps or stages in other steps or others.
In the description of the present specification, reference to the terms "some embodiments," "other embodiments," "desired embodiments," and the like, means that a particular feature, structure, material, or characteristic described in connection with the embodiment or example is included in at least one embodiment or example of the invention. In this specification, schematic descriptions of the above terms do not necessarily refer to the same embodiment or example.
The technical features of the above-described embodiments may be arbitrarily combined, and all possible combinations of the technical features in the above-described embodiments are not described for brevity of description, however, as long as there is no contradiction between the combinations of the technical features, they should be considered as the scope of the description.
The above examples illustrate only a few embodiments of the invention, which are described in detail and are not to be construed as limiting the scope of the invention. It should be noted that it will be apparent to those skilled in the art that several variations and modifications can be made without departing from the spirit of the invention, which are all within the scope of the invention. Accordingly, the scope of protection of the present invention is to be determined by the appended claims.

Claims (7)

1. A biological signal acquisition circuit, comprising:
at least one sensor unit for acquiring corresponding biological signals;
the level matching circuit is provided with level adjustment channels with the same number as the sensor units, the input end of each channel of level adjustment channel is connected with the output end of one sensor unit, and the level matching circuit is used for uniformly processing the voltage of analog signals output by each sensor unit and then outputting the analog signals through the output end of the level adjustment channel, so that the sensor units of different level systems are subjected to level matching through the level matching circuit;
the multi-channel analog switching circuit is connected with the output end of each level adjustment channel, and is used for carrying out time-sharing gating on the output end of each level adjustment channel and outputting a gated analog signal through the output end of the multi-channel analog switching circuit;
the analog-to-digital converter is connected with the output end of the multi-channel analog switching circuit and is used for carrying out analog-to-digital conversion on the analog signal output by the output end of the multi-channel analog switching circuit; the analog-to-digital converter acquires the data of the sensor units one by one through the multi-channel analog switching circuit and synchronously scans the data so that different sensor units share one analog-to-digital converter, and therefore sensor signals of different sensor units adopt the same ADC parameters, including the same ADC sampling rate and sampling interval;
each path of level adjustment channel comprises an NMOS tube, a source electrode of the NMOS tube is used as an input end of the level adjustment channel, a drain electrode of the NMOS tube is used as an output end of the level adjustment channel, a grid electrode and a source electrode of the NMOS tube are connected with a power supply voltage end, a drain electrode of the NMOS tube is connected with a working voltage end, each path of power supply voltage end connected with the level adjustment channel is a power supply voltage end of a corresponding sensor unit, a first resistor is arranged between the power supply voltage end and the source electrode, and a second resistor is arranged between the working voltage end and the drain electrode.
2. The biosignal acquisition circuit of claim 1, wherein the multi-channel analog switching circuit comprises an LTC6091 chip, wherein a first non-inverting input and a second non-inverting input of the LTC6091 chip are each connected to an output of the level matching circuit, wherein a first inverting input and a second inverting input of the LTC6091 chip are grounded, wherein a first output disable pin of the LTC6091 chip is configured to receive a chip select signal, wherein the chip select signal is connected to a second output disable pin of the LTC6091 chip through an inverter, and wherein the first output and the second output of the LTC6091 chip are connected to the output of the multi-channel analog switching circuit.
3. The biosignal acquisition circuit of claim 1, wherein the at least one sensor unit comprises an ECG sensor unit.
4. The biosignal acquisition circuit of claim 1, wherein the at least one sensor unit comprises a PPG sensor unit.
5. The biosignal acquisition circuit of claim 1, wherein the at least one sensor unit comprises a temperature sensor unit.
6. A mouse comprising a mouse housing, further comprising a biological signal acquisition circuit according to any one of claims 1-5, wherein the at least one sensor unit is provided on a side of the mouse housing.
7. The mouse of claim 6, wherein each of the sensor units is integrated in a chip.
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