CN1139366C - Laser therapeutic machine - Google Patents

Laser therapeutic machine Download PDF

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Publication number
CN1139366C
CN1139366C CNB00103958XA CN00103958A CN1139366C CN 1139366 C CN1139366 C CN 1139366C CN B00103958X A CNB00103958X A CN B00103958XA CN 00103958 A CN00103958 A CN 00103958A CN 1139366 C CN1139366 C CN 1139366C
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laser
wavelength
pumping
optical fiber
crystal
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CN1314132A (en
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沈鸿元
曾瑞荣
黄呈辉
林文雄
黄文�
黄见洪
张戈
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Fujian Institute of Research on the Structure of Matter of CAS
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Fujian Institute of Research on the Structure of Matter of CAS
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Abstract

The present invention relates to a Nd: YAG laser treatment apparatus with a wavelength of 1338 nm or double wavelengths of 1319 nm and 1338 nm at the same time, which belongs to a medical apparatus. The present invention is composed of Nd: YAG crystals, a special optical resonant cavity, a pump light source, a power supply, silicon fiber, a fiber pen, guiding light, etc., wherein the special optical resonant cavity can realize oscillation of 1338 nm or double-wavelength oscillation of 1319 nm and 1338 nm at the same time to generate lasers of 1338 nm or double-wavelength lasers of 1319 nm and 1338 nm. The present invention integrates the functions of quick vaporizing and cutting speed, favorable hemostasis effect, etc. in clinic treatment, and is a novel wave-band laser treatment apparatus with clinical application value.

Description

Laser therapy aparatus
Laser therapy aparatus of the present invention, relate to laser medical equipment, it is to be 1338nm or to produce 1319nm simultaneously and two kinds of laser therapy aparatuses of 1338nm dual-wavelength laser with the wavelength that common medical optical fiber transmits, they have sufficiently high laser output power or energy, can be flexibly, peep treatment in being advantageously used in body surface and the body.
Being widely used in clinical 1064nmNd:YAG tissue by laser at present has darker penetration capacity, has good tissue coagulation and haemostatic effect, but the ability that cuts and organizes.And the penetration depth of 10600nm laser in tissue is extremely shallow, has the favorable tissue cutting function but haemostatic effect is poor.We have measured distilled water to the radiating absorptance of different wave length (seeing Table 1.), find that water is slightly less than 1341.4nm to 1319nm and the radiating absorbing wavelength of 1338nm, are about 8.8 times and 13.4 times of 1064nmNd:YAG laser, but than 10600nmCO 2Laser, 2800nmEr:YAG laser and 2100nmHo:YAG laser are little, we found 1341.4nm laser in clinical treatment, have concurrently 1064nmNd:AG laser good solidify, haemostatic effect and 10600nm cut, the fast advantage of gasification rate.By the data of table 1. as can be seen, 1319nm and 1338nm laser particularly 1338nm laser also have the function of similar 1341.4nm laser, so also be the new wave band of laser therapy apparatus that clinical value is arranged.
Table 1. distilled water is to the absorptance of near-infrared radiation
Wavelength (nm) 1064 1079.5 1319 1338 1341.4
Absorptance (cm -1) 0.2065 0.2125 1.8158 2.7774 2.9456
Trivalent neodymium ion (Nd 3+) in some mineral crystals 4F 3/2- 4I 13/2Transition is in the 1300nm wave band, has provided the crystalline basic parameter of some neodymium lasers in the table 2., the YAlO that records based on us 3Nd in the crystal 3+Parameter (H.Y.Shen, T.Q.Lian, the R.R.Zeng of ionic transition cross section σ and fluorescence lifetime τ, Y.P.Zhou, G.F.Yu, C.H.Huang, and Z.D.Zeng, " Measurement of the Stimulated Emmission Cross section for 4F 3/2- 4I 13/2Transition of Nd 3+In YAlO 3Crystal ", IEEEJ.Quantum Electron., Vol.25, No.2,144 (1989)), compare Nd:YVO although find the product of σ τ 4Smaller, but this crystal physical and chemical performance can grow the large scale laser bar that processing dimension reaches φ 8-10 * 150-200mm near Nd:YAG.We have used Nd:YAlO 3Crystal has obtained the continuous laser of 1300nm wave band maximum power output-195 watt (H.Y.Shen, Y.P.Zhon, R.R.Zeng so far, G.F.Yu, C.H.Huang, Z.D.Zeng, W.J.Zhang, W.X.Lin and Q.J.Ye " LaserAction of Nd:YAlO 3Crystal At 1300nm " J.Appl.Phys.70 (30) 1880 (1991)) and the laser-5.31 of maximum output energy joule (H.Y.Shen, Y.P.Zhon, R.R.Zeng; G.F.Yu, C.H.Huang, Z.D.Zeng; W.J.Zhang, W.X.Lin andQ.J.Ye, Optic ﹠amp; Laser Technology Vol.23, No.6,366 (1991)).And invented this crystalline laser therapy aparatus, obtained U.S.'s patent of invention, the patent No. 5910140.Applied for Chinese patent, number of patent application 931177197.
Since the nineties, along with the develop rapidly of LD, Nd:YVO 4Crystal is subject to people's attention once more, but because this crystal, thermal conductivity is little than Nd:YAG.When using, must reduce the influence of heat effect to laser output power as laser therapy aparatus.We have declared Nd-doped yttrium vanadate (Nd:YVO on March 29th, 1999 to State Intellectual Property Office of the People's Republic of China 4) application of laser therapy aparatus patent of invention, and accept application number 99102626.8 on March 29th, 1999.
The basic parameter of table 2, some neodymium-doped laser crystals
Crystal Nd:YAG Nd:BEL Nd:YAlO 3 Nd:YVO 4
Fluorescence lifetime τ (μ s) 230 144 150 99
4F 3/2- 4I 13/2
Wavelength 1338/1319 1351 1341.4 1342
σ(×10 -29cm 2) 0.92/0.90 0.4 22 6.0
στ(×10 -19cm 2μs) 211.6/207 57.6 330 594
With Nd:YAlO 3And Nd:YVO 4Relatively, Nd in the YAG crystal 3+Ion 4F 3/2Energy level R 2Configuration arrives 4I 13/2Energy level X 1And X 3The laser transition cross section of configuration is less, is respectively Nd:YAlO 30.418,0.409 times of same energy level transition cross section, and Nd:YVO 40.153,0.150 times of same energy level transition cross section, the product of σ τ is also little than these two kinds of crystal.So the threshold value of 1319nm and 1338nmNd:YAG laser is higher, lasing efficiency is lower, and laser output is less.Jack Marling, " 1.05-1.44 μ m Tunability and performanceof the CW Nd 3+: YAG Laser ", IEEEJ.Quantum Electronics, Vol.QE-14, No.1,56 (1978) reports have obtained 37 watts of 1319nm laser when input 5KW.Zhang Xiurong, Wu Guangzhao, " continuous 1.32 μ m Nd 3+: the single mode of YAG laser instrument and tuning running ", Chinese laser, Vol.12, No.7,440 (1985) reports have obtained 30 watt of 1.32 μ m laser when input 6.2KW.We have obtained 47W1319nm laser (Lin Wenxiong, Zhou Yuping, Ceng Ruirong, Shen Hongyuan, " singlet line 1319nmNd:YAGTEM when input 6KW 00The development of mode laser ", Chinese laser, Vol.A23, No.5,444 (1996)).Adopt the repetitive rate pumping source of suitable pulse width, increase and surpass the ratio of laser threshold part in the lamp luminous power in the lamp luminous power, there is more fractional conversion to become the mean power of laser in the mean power that lamp is launched, can improve the conversion efficiency of laser effectively, thereby improve the mean power of laser output.
See that from table 1 water is 1.53 times of 1319nm to the absorptance of 1338nm, more near the absorptance of 1341.4nm, its therapeutic effect and 1341.4nm in clinical is more approaching.Because the transition of 1319nm and 1338nm spectral line is close, the transmitance that only needs suitably to increase 1319nm in the outgoing mirror just can make the Nd:YAG laser works on the singlet line of 1338nm.
In addition, because the transition cross section of 1319nm and 1338nm spectral line is close, so the threshold value of these two spectral lines is very approaching, theory (Shen Hongyuan, " oscillating condition of multiwavelength laser ", Chinese Physics Letter Vol.7 according to our foundation, No.4,174 (1990)), these two spectral lines are very easy to realize starting of oscillation simultaneously, realize dual wavelength running simultaneously.Because the wave amplitude of these two spectral lines is in the different parts of operation material rod axle in resonator cavity, so the dual-wavelength laser of these two spectral lines can utilize the energy storage of reversing in the operation material more fully than single wavelength laser, thereby obtain the output bigger than singlet laser.
Based on above consideration, two kinds of laser therapy aparatuses such as the 1338nm that the present invention proposes and while 1319nm and 1338nm dual wavelength Nd:YAG are possible.
Purpose of the present invention: be to utilize present widely used Nd:YAG laser crystal, based on Nd 3+Ion 4F 3/2Energy level R 2Configuration arrives 4I 13/2Energy level X 1And X 3The 1319nm of configuration transition and 1338nm spectral line, development 1338nm and two kinds of new wavelength Nd:YAG laser therapy aparatuses such as 1319nm and 1338nm dual wavelength simultaneously are used for shining, solidify, operative treatments such as hemostasis, carbonization, gasification, cutting.Recent available krypton lamp and xenon flash lamp pumping, after treating to descend as the 808nm laser diode price of pumping, available laser diode is as pumping.
Below be example with the 1338nm laser therapy aparatus, the concrete scheme of the present invention that realizes is provided: (1319nm and 1338nm dual-wavelength laser therapy apparatus only need outgoing mirror is changed into 1319nm and the 1338nm transmitance outgoing mirror near the double-colored dielectric mirror replacement 1338nm laser instrument that equates simultaneously, change reflecting mirror into to 1319nm and 1338nm total reflection simultaneously dielectric mirror.To ns and ps laser, only need to insert accent Q or locked mode element) at intracavity.
1338nm and export two kinds of neodymium-doped yttrium-aluminum garnets (Nd:YAG) laser therapy aparatus of 1319nm and 1338nm simultaneously is by the Nd:YAG crystal and be used for the described crystal of pumping and make described crystal formation active ions (Nd 3+Ion) pumping system of population inversion distribution, and corresponding optical resonator is formed.Under the pumping excitation, accumulate in Nd 3+Ion 4F 3/2Metastable level R 2The particle of configuration transits to 4I 13/2The X of energy level 1Configuration and X 3Configuration generation 1319 and 1338nm radiation produce 1338nm laser or produce 1319nm simultaneously and the 1338nm dual-wavelength laser in corresponding resonator cavity.
Above-mentioned laser is in the transparent wavelength scope of common medical optical fiber, with the respective wavelength laser of resonator cavity output by inject lens (or with resonator cavity outgoing mirror and collecting lens unite two into one can the output laser convergence to the resonator cavity outgoing mirror of described medical optical fiber one end) converge to medical optical fiber one end that transmits 1338nm and transmit described while 1319nm and 1338nm dual-wavelength laser, through optical fiber light-guiding, by link to each other with the described medical optical fiber other end with described respective wavelength laser irradiation to the Optical fibre writing appliance of required treatment lesions position or the Optical fibre writing appliance that contains the finishing tool head with laser irradiation to focus, focus is treated.Because water is moderate to the absorptance of above-mentioned wavelength laser, so moderate in the penetration depth of tissue.
Arrive focus with treating with laser with the red semiconductor laser of light path by fiber guides, as the indication light source of focus treatment with laser.
Above-mentioned treatment comprises repetitive rate pulsed drive source that the Continuous Drive source that can continuously change input power or energy or pulse width are suitable with the pumping source of laser and as the krypton lamp or the xenon lamp of pumping lamp.
Above-mentioned treatment also can use laser diode and drive source thereof as pumping source with laser.
Above-mentioned laser aid cools off with self-loopa cooling cooling system.
The invention will be further described below in conjunction with accompanying drawing:
Fig. 1 is the pie graph of lamp pumping 1338nmNd:YAG laser therapy aparatus example of the present invention.
Fig. 2 is the pie graph of the laser diode side pumped 1338nmNd:YAG laser therapy aparatus of the present invention example.
Fig. 3 is a laser diode end-face pump 1338nmNd:YAG laser therapy aparatus example pie graph of the present invention.
(1) is the Nd:YAG crystal among Fig. 1, (2) be pumping with krypton lamp or xenon lamp, (3) be the optical filtering pipe of elimination pumping lamp ultraviolet radiation, (4) hard-pressed bale formula ellipse or round laser pump cavity, intracavity is full of the medium liquid coolant, cooling work material and pumping lamp, (5) be dielectric mirror to the optical maser wavelength total reflection, (6) be the outgoing mirror of laser, it is characterized in that a planoconvex lens, planar ends plating deielectric-coating and completely reflecting mirror form laser resonator, and convex surface plays focussing force, will export the laser focusing injection fibre, (7) be self-loopa cooling device, (8) be power supply, can be output current increases continuously 30 amperes uninterruptable power from 0, or the output average current is increased to 30 amperes the suitable repetitive rate electric current of pulse width from 0, perhaps export the pulse power of energy adjustable, (9) treated focus usefulness with the red laser diode of light path indication as indication with laser, (10) are the medical optical fibers of 200 μ m-600 μ m for internal diameter, and (11) are for being furnished with the Optical fibre writing appliance of suitable cutter head.
After starting laser, change the operating current of lamp or the energy storage of power supply, from optical fiber output to focus implement to shine, solidify, carbonization, gasification and required laser power or the energy of cutting, focus is treated.
Among Fig. 2 (1) be the Nd:YAG crystal, with a plurality of LD (12) side-pumping, with the pump light vertical direction on heat sink (not the drawing among the figure) of semiconductor cooler refrigeration, extract the heat that the operation material operation process produces, (5), (6) are total reflection dielectric mirror and the output medium mirrors similar to Fig. 1, (13) be LD and indication drive source with red laser diode, (10), (11) are optical fiber and are furnished with the Optical fibre writing appliance of suitable cutter head that its effect is similar to Fig. 1.
Among Fig. 3 (1) be with Fig. 1 in identical Nd:YAG crystal bar, rod but (does not draw among the figure) with semiconductor freezer cold, (5) be the deielectric-coating that is plated on the Nd:YAG crystal bar end face, it is to described optical maser wavelength total reflection, anti-reflection to the pump light that the 808nm semiconductor laser diode of pumping sends, (6) be plano-convex output-focus lamp, act on identical with (6) among Fig. 1, (15) be that Raymond J.Beach is at Applied Optics Vol.35, No.2,2005 (1996) lens ducts that propose, it is poly-near the Nd:YAG crystal bar end face with the laser that continuous or quasi-continuous many LD of high power or high-average power send, (16) be quasi-continuous many LD of high power or high-average power, (10) among (10) and (11) and Fig. 1, (11) identical.
1319nm and 1338nm while dual-wavelength laser therapy apparatus only needs the dielectric mirror that (5) completely reflecting mirror among Fig. 1,2,3 and the dielectric mirror on (6) output focus lamp be changed respective wavelength is got final product as mentioned above.(completely reflecting mirror of LD end pumping example directly replaces with the all-dielectric film that is plated on the plane rod end among Fig. 3, and this completely reflecting mirror deielectric-coating is anti-reflection to the 808nm pump light.)
Implement typical scenario of the present invention: the 1338nm laser therapy aparatus with the lamp pumping is example (other wavelength only needs the corresponding dielectric mirror of conversion resonator cavity to get final product as mentioned above).After the energized (8), self-loopa cooling device (7) is about to deionized water in the water tank and pumps into and contain in Nd:YAG rod (1) and the sealing laser pump cavity of pumping with krypton lamp or xenon lamp (2), optionally can cool off in the device by secondary cooling water (using tap water usually) or with compressor for refrigeration in self-loopa and cool off deionized water in the self-loopa water tank.Start the pre-burning that sequential control circuit in the power supply is finished pumping lamp automatically by latching switch, pumping lamp is operated in keeps current status.According to doctor's needs therapy apparatus is preset on the corresponding pumping lamp operating current of required laser power, that exports with red laser diode (9) with indication aims at Optical fibre writing appliance (11) focus that needs treatment with treatment laser with the red laser of light path, step on foot switch, pumping lamp (2) promptly is operated on the required corresponding electric current of laser power of treatment, the light that this moment, pumping lamp sent focuses on the Nd:YAG crystal Nd in the YAG crystal in laser pump cavity 3+In resonator cavity (5) (6), produce the laser of respective wavelength behind the ionic absorption pump light, by condenser lens laser is injected the medical optical fiber that core diameter is 200-600 μ m with the outgoing mirror one, by the Optical fibre writing appliance (11) of aiming at focus with laser irradiation on focus to focus shine, solidify, carbonization, gasification or cutting treatment, optionally Optical fibre writing appliance can be mixed suitable cutter head to cooperate the needs of clinical operation.

Claims (8)

1. a laser therapy aparatus comprises the Nd:YAG crystal; The pumping system that is used for the described crystal of pumping and described crystal formation active ions population inversion is distributed; And optical resonator, it is characterized in that: utilize Nd in the Nd:YAG crystal 3+Ion 4F 3/2The R of energy level 2Configuration arrives 4I 13/2The X of energy level 3The 1338nm radiation that the configuration transition produces produces the 1338nm vibration in special optical resonator, and output 1338nm laser, and described wavelength laser is in the transparent wavelength scope of medical optical fiber, and above-mentioned wavelength laser is moderate in the penetration depth of tissue.
2. a laser therapy aparatus comprises the Nd:YAG crystal; The pumping system that is used for the described crystal of pumping and described crystal formation active ions population inversion is distributed; And optical resonator, it is characterized in that: utilize Nd in the Nd:YAG crystal 3+Ion 4F 3/2The R of energy level 2Configuration arrives 4I 13/2The X of energy level 1Configuration and X 31319nm and 1338nm radiation that the configuration transition produces, in special optical resonator, produce 1319nm and 1338nm vibration simultaneously, and export 1319nm and 1338nm dual-wavelength laser simultaneously, described dual-wavelength laser is in the transparent wavelength scope of medical optical fiber, and above-mentioned wavelength laser is moderate in the penetration depth of tissue.
3. two kinds of laser therapy aparatuses as claimed in claim 1 or 2 is characterized in that: they also comprise transmission 1338nm or transmit 1319nm simultaneously and the medical optical fiber of 1338nm dual-wavelength laser; With the respective wavelength laser convergence of resonator cavity output injection lens to described medical optical fiber one end, or the resonator cavity outgoing mirror that can the output laser convergence arrives described medical optical fiber one end that resonator cavity outgoing mirror and collecting lens are united two into one; Link to each other with the described medical optical fiber other end with described respective wavelength laser irradiation to the Optical fibre writing appliance of required treatment lesions position or contain the Optical fibre writing appliance of special light cutter head.
4. two kinds of laser therapy aparatuses as claimed in claim 1 or 2 is characterized in that: it comprises also and the semiconductor laser of described treatment laser with the light path indication that the red visible laser that this semiconductor laser sends is used for being treated the indication of focus.
5. laser therapy aparatus as claimed in claim 1 or 2 is characterized in that: the pumping source of pumping system comprise can continuously change input power or energy continuously, pulse or repetitive rate pulsed drive source and as the krypton lamp or the xenon lamp of pumping lamp.
6. two kinds of laser therapy aparatuses as claimed in claim 1 or 2 is characterized in that: comprise and transfer Q and locked mode element, produce accent Q and the mode-locked laser of ns and ps.
7. two kinds of laser therapy aparatuses as claimed in claim 5 is characterized in that: the pumping source of described pumping system is laser diode and drive source thereof.
8. laser therapy aparatus as claimed in claim 1 or 2 is characterized in that: it also comprises the cooling system of described laser aid.
CNB00103958XA 2000-03-16 2000-03-16 Laser therapeutic machine Expired - Fee Related CN1139366C (en)

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Publication number Priority date Publication date Assignee Title
CN101919733B (en) * 2010-09-07 2012-04-11 中国科学院长春光学精密机械与物理研究所 Double-wavelength high-power semiconductor laser synthetic therapeutic apparatus
CN103536358A (en) * 2012-07-17 2014-01-29 杨涛 Laser bleeding stopping device

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