CN1139366C - laser therapy machine - Google Patents

laser therapy machine Download PDF

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CN1139366C
CN1139366C CNB00103958XA CN00103958A CN1139366C CN 1139366 C CN1139366 C CN 1139366C CN B00103958X A CNB00103958X A CN B00103958XA CN 00103958 A CN00103958 A CN 00103958A CN 1139366 C CN1139366 C CN 1139366C
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laser
wavelength
pumping
yag
dual
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CN1314132A (en
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沈鸿元
曾瑞荣
黄呈辉
林文雄
黄文�
黄见洪
张戈
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Fujian Institute of Research on the Structure of Matter of CAS
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Abstract

1338nm或同时1319nm和1338nm双波长Nd:YAG激光治疗机属医疗设备。它由Nd:YAG晶体、特殊光学谐振腔、泵浦光源和电源、石英光纤、光纤笔以及引导光等部分组成。所用特殊光学谐振腔能实现1338nm振荡或同时实现1319nm和1338nm双波长振荡,产生1338nm激光或1319nm和1338nm双波长激光,在临床治疗中兼具汽化、切割速度快和止血效果好等功能,是一种具有临床应用价值的新波段激光治疗机。

Figure 00103958

1338nm or simultaneous 1319nm and 1338nm dual-wavelength Nd:YAG laser therapy machine is a medical device. It consists of Nd:YAG crystal, special optical resonant cavity, pumping light source and power supply, quartz optical fiber, optical fiber pen, and guiding light. The special optical resonant cavity used can realize 1338nm oscillation or 1319nm and 1338nm dual-wavelength oscillation at the same time, and generate 1338nm laser or 1319nm and 1338nm dual-wavelength laser, which has the functions of vaporization, fast cutting speed and good hemostasis effect in clinical treatment. A new band laser therapy machine with clinical application value.

Figure 00103958

Description

Laser therapy aparatus
Laser therapy aparatus of the present invention, relate to laser medical equipment, it is to be 1338nm or to produce 1319nm simultaneously and two kinds of laser therapy aparatuses of 1338nm dual-wavelength laser with the wavelength that common medical optical fiber transmits, they have sufficiently high laser output power or energy, can be flexibly, peep treatment in being advantageously used in body surface and the body.
Being widely used in clinical 1064nmNd:YAG tissue by laser at present has darker penetration capacity, has good tissue coagulation and haemostatic effect, but the ability that cuts and organizes.And the penetration depth of 10600nm laser in tissue is extremely shallow, has the favorable tissue cutting function but haemostatic effect is poor.We have measured distilled water to the radiating absorptance of different wave length (seeing Table 1.), find that water is slightly less than 1341.4nm to 1319nm and the radiating absorbing wavelength of 1338nm, are about 8.8 times and 13.4 times of 1064nmNd:YAG laser, but than 10600nmCO 2Laser, 2800nmEr:YAG laser and 2100nmHo:YAG laser are little, we found 1341.4nm laser in clinical treatment, have concurrently 1064nmNd:AG laser good solidify, haemostatic effect and 10600nm cut, the fast advantage of gasification rate.By the data of table 1. as can be seen, 1319nm and 1338nm laser particularly 1338nm laser also have the function of similar 1341.4nm laser, so also be the new wave band of laser therapy apparatus that clinical value is arranged.
Table 1. distilled water is to the absorptance of near-infrared radiation
Wavelength (nm) 1064 1079.5 1319 1338 1341.4
Absorptance (cm -1) 0.2065 0.2125 1.8158 2.7774 2.9456
Trivalent neodymium ion (Nd 3+) in some mineral crystals 4F 3/2- 4I 13/2Transition is in the 1300nm wave band, has provided the crystalline basic parameter of some neodymium lasers in the table 2., the YAlO that records based on us 3Nd in the crystal 3+Parameter (H.Y.Shen, T.Q.Lian, the R.R.Zeng of ionic transition cross section σ and fluorescence lifetime τ, Y.P.Zhou, G.F.Yu, C.H.Huang, and Z.D.Zeng, " Measurement of the Stimulated Emmission Cross section for 4F 3/2- 4I 13/2Transition of Nd 3+In YAlO 3Crystal ", IEEEJ.Quantum Electron., Vol.25, No.2,144 (1989)), compare Nd:YVO although find the product of σ τ 4Smaller, but this crystal physical and chemical performance can grow the large scale laser bar that processing dimension reaches φ 8-10 * 150-200mm near Nd:YAG.We have used Nd:YAlO 3Crystal has obtained the continuous laser of 1300nm wave band maximum power output-195 watt (H.Y.Shen, Y.P.Zhon, R.R.Zeng so far, G.F.Yu, C.H.Huang, Z.D.Zeng, W.J.Zhang, W.X.Lin and Q.J.Ye " LaserAction of Nd:YAlO 3Crystal At 1300nm " J.Appl.Phys.70 (30) 1880 (1991)) and the laser-5.31 of maximum output energy joule (H.Y.Shen, Y.P.Zhon, R.R.Zeng; G.F.Yu, C.H.Huang, Z.D.Zeng; W.J.Zhang, W.X.Lin andQ.J.Ye, Optic ﹠amp; Laser Technology Vol.23, No.6,366 (1991)).And invented this crystalline laser therapy aparatus, obtained U.S.'s patent of invention, the patent No. 5910140.Applied for Chinese patent, number of patent application 931177197.
Since the nineties, along with the develop rapidly of LD, Nd:YVO 4Crystal is subject to people's attention once more, but because this crystal, thermal conductivity is little than Nd:YAG.When using, must reduce the influence of heat effect to laser output power as laser therapy aparatus.We have declared Nd-doped yttrium vanadate (Nd:YVO on March 29th, 1999 to State Intellectual Property Office of the People's Republic of China 4) application of laser therapy aparatus patent of invention, and accept application number 99102626.8 on March 29th, 1999.
The basic parameter of table 2, some neodymium-doped laser crystals
Crystal Nd:YAG Nd:BEL Nd:YAlO 3 Nd:YVO 4
Fluorescence lifetime τ (μ s) 230 144 150 99
4F 3/2- 4I 13/2
Wavelength 1338/1319 1351 1341.4 1342
σ(×10 -29cm 2) 0.92/0.90 0.4 22 6.0
στ(×10 -19cm 2μs) 211.6/207 57.6 330 594
With Nd:YAlO 3And Nd:YVO 4Relatively, Nd in the YAG crystal 3+Ion 4F 3/2Energy level R 2Configuration arrives 4I 13/2Energy level X 1And X 3The laser transition cross section of configuration is less, is respectively Nd:YAlO 30.418,0.409 times of same energy level transition cross section, and Nd:YVO 40.153,0.150 times of same energy level transition cross section, the product of σ τ is also little than these two kinds of crystal.So the threshold value of 1319nm and 1338nmNd:YAG laser is higher, lasing efficiency is lower, and laser output is less.Jack Marling, " 1.05-1.44 μ m Tunability and performanceof the CW Nd 3+: YAG Laser ", IEEEJ.Quantum Electronics, Vol.QE-14, No.1,56 (1978) reports have obtained 37 watts of 1319nm laser when input 5KW.Zhang Xiurong, Wu Guangzhao, " continuous 1.32 μ m Nd 3+: the single mode of YAG laser instrument and tuning running ", Chinese laser, Vol.12, No.7,440 (1985) reports have obtained 30 watt of 1.32 μ m laser when input 6.2KW.We have obtained 47W1319nm laser (Lin Wenxiong, Zhou Yuping, Ceng Ruirong, Shen Hongyuan, " singlet line 1319nmNd:YAGTEM when input 6KW 00The development of mode laser ", Chinese laser, Vol.A23, No.5,444 (1996)).Adopt the repetitive rate pumping source of suitable pulse width, increase and surpass the ratio of laser threshold part in the lamp luminous power in the lamp luminous power, there is more fractional conversion to become the mean power of laser in the mean power that lamp is launched, can improve the conversion efficiency of laser effectively, thereby improve the mean power of laser output.
See that from table 1 water is 1.53 times of 1319nm to the absorptance of 1338nm, more near the absorptance of 1341.4nm, its therapeutic effect and 1341.4nm in clinical is more approaching.Because the transition of 1319nm and 1338nm spectral line is close, the transmitance that only needs suitably to increase 1319nm in the outgoing mirror just can make the Nd:YAG laser works on the singlet line of 1338nm.
In addition, because the transition cross section of 1319nm and 1338nm spectral line is close, so the threshold value of these two spectral lines is very approaching, theory (Shen Hongyuan, " oscillating condition of multiwavelength laser ", Chinese Physics Letter Vol.7 according to our foundation, No.4,174 (1990)), these two spectral lines are very easy to realize starting of oscillation simultaneously, realize dual wavelength running simultaneously.Because the wave amplitude of these two spectral lines is in the different parts of operation material rod axle in resonator cavity, so the dual-wavelength laser of these two spectral lines can utilize the energy storage of reversing in the operation material more fully than single wavelength laser, thereby obtain the output bigger than singlet laser.
Based on above consideration, two kinds of laser therapy aparatuses such as the 1338nm that the present invention proposes and while 1319nm and 1338nm dual wavelength Nd:YAG are possible.
Purpose of the present invention: be to utilize present widely used Nd:YAG laser crystal, based on Nd 3+Ion 4F 3/2Energy level R 2Configuration arrives 4I 13/2Energy level X 1And X 3The 1319nm of configuration transition and 1338nm spectral line, development 1338nm and two kinds of new wavelength Nd:YAG laser therapy aparatuses such as 1319nm and 1338nm dual wavelength simultaneously are used for shining, solidify, operative treatments such as hemostasis, carbonization, gasification, cutting.Recent available krypton lamp and xenon flash lamp pumping, after treating to descend as the 808nm laser diode price of pumping, available laser diode is as pumping.
Below be example with the 1338nm laser therapy aparatus, the concrete scheme of the present invention that realizes is provided: (1319nm and 1338nm dual-wavelength laser therapy apparatus only need outgoing mirror is changed into 1319nm and the 1338nm transmitance outgoing mirror near the double-colored dielectric mirror replacement 1338nm laser instrument that equates simultaneously, change reflecting mirror into to 1319nm and 1338nm total reflection simultaneously dielectric mirror.To ns and ps laser, only need to insert accent Q or locked mode element) at intracavity.
1338nm and export two kinds of neodymium-doped yttrium-aluminum garnets (Nd:YAG) laser therapy aparatus of 1319nm and 1338nm simultaneously is by the Nd:YAG crystal and be used for the described crystal of pumping and make described crystal formation active ions (Nd 3+Ion) pumping system of population inversion distribution, and corresponding optical resonator is formed.Under the pumping excitation, accumulate in Nd 3+Ion 4F 3/2Metastable level R 2The particle of configuration transits to 4I 13/2The X of energy level 1Configuration and X 3Configuration generation 1319 and 1338nm radiation produce 1338nm laser or produce 1319nm simultaneously and the 1338nm dual-wavelength laser in corresponding resonator cavity.
Above-mentioned laser is in the transparent wavelength scope of common medical optical fiber, with the respective wavelength laser of resonator cavity output by inject lens (or with resonator cavity outgoing mirror and collecting lens unite two into one can the output laser convergence to the resonator cavity outgoing mirror of described medical optical fiber one end) converge to medical optical fiber one end that transmits 1338nm and transmit described while 1319nm and 1338nm dual-wavelength laser, through optical fiber light-guiding, by link to each other with the described medical optical fiber other end with described respective wavelength laser irradiation to the Optical fibre writing appliance of required treatment lesions position or the Optical fibre writing appliance that contains the finishing tool head with laser irradiation to focus, focus is treated.Because water is moderate to the absorptance of above-mentioned wavelength laser, so moderate in the penetration depth of tissue.
Arrive focus with treating with laser with the red semiconductor laser of light path by fiber guides, as the indication light source of focus treatment with laser.
Above-mentioned treatment comprises repetitive rate pulsed drive source that the Continuous Drive source that can continuously change input power or energy or pulse width are suitable with the pumping source of laser and as the krypton lamp or the xenon lamp of pumping lamp.
Above-mentioned treatment also can use laser diode and drive source thereof as pumping source with laser.
Above-mentioned laser aid cools off with self-loopa cooling cooling system.
The invention will be further described below in conjunction with accompanying drawing:
Fig. 1 is the pie graph of lamp pumping 1338nmNd:YAG laser therapy aparatus example of the present invention.
Fig. 2 is the pie graph of the laser diode side pumped 1338nmNd:YAG laser therapy aparatus of the present invention example.
Fig. 3 is a laser diode end-face pump 1338nmNd:YAG laser therapy aparatus example pie graph of the present invention.
(1) is the Nd:YAG crystal among Fig. 1, (2) be pumping with krypton lamp or xenon lamp, (3) be the optical filtering pipe of elimination pumping lamp ultraviolet radiation, (4) hard-pressed bale formula ellipse or round laser pump cavity, intracavity is full of the medium liquid coolant, cooling work material and pumping lamp, (5) be dielectric mirror to the optical maser wavelength total reflection, (6) be the outgoing mirror of laser, it is characterized in that a planoconvex lens, planar ends plating deielectric-coating and completely reflecting mirror form laser resonator, and convex surface plays focussing force, will export the laser focusing injection fibre, (7) be self-loopa cooling device, (8) be power supply, can be output current increases continuously 30 amperes uninterruptable power from 0, or the output average current is increased to 30 amperes the suitable repetitive rate electric current of pulse width from 0, perhaps export the pulse power of energy adjustable, (9) treated focus usefulness with the red laser diode of light path indication as indication with laser, (10) are the medical optical fibers of 200 μ m-600 μ m for internal diameter, and (11) are for being furnished with the Optical fibre writing appliance of suitable cutter head.
After starting laser, change the operating current of lamp or the energy storage of power supply, from optical fiber output to focus implement to shine, solidify, carbonization, gasification and required laser power or the energy of cutting, focus is treated.
Among Fig. 2 (1) be the Nd:YAG crystal, with a plurality of LD (12) side-pumping, with the pump light vertical direction on heat sink (not the drawing among the figure) of semiconductor cooler refrigeration, extract the heat that the operation material operation process produces, (5), (6) are total reflection dielectric mirror and the output medium mirrors similar to Fig. 1, (13) be LD and indication drive source with red laser diode, (10), (11) are optical fiber and are furnished with the Optical fibre writing appliance of suitable cutter head that its effect is similar to Fig. 1.
Among Fig. 3 (1) be with Fig. 1 in identical Nd:YAG crystal bar, rod but (does not draw among the figure) with semiconductor freezer cold, (5) be the deielectric-coating that is plated on the Nd:YAG crystal bar end face, it is to described optical maser wavelength total reflection, anti-reflection to the pump light that the 808nm semiconductor laser diode of pumping sends, (6) be plano-convex output-focus lamp, act on identical with (6) among Fig. 1, (15) be that Raymond J.Beach is at Applied Optics Vol.35, No.2,2005 (1996) lens ducts that propose, it is poly-near the Nd:YAG crystal bar end face with the laser that continuous or quasi-continuous many LD of high power or high-average power send, (16) be quasi-continuous many LD of high power or high-average power, (10) among (10) and (11) and Fig. 1, (11) identical.
1319nm and 1338nm while dual-wavelength laser therapy apparatus only needs the dielectric mirror that (5) completely reflecting mirror among Fig. 1,2,3 and the dielectric mirror on (6) output focus lamp be changed respective wavelength is got final product as mentioned above.(completely reflecting mirror of LD end pumping example directly replaces with the all-dielectric film that is plated on the plane rod end among Fig. 3, and this completely reflecting mirror deielectric-coating is anti-reflection to the 808nm pump light.)
Implement typical scenario of the present invention: the 1338nm laser therapy aparatus with the lamp pumping is example (other wavelength only needs the corresponding dielectric mirror of conversion resonator cavity to get final product as mentioned above).After the energized (8), self-loopa cooling device (7) is about to deionized water in the water tank and pumps into and contain in Nd:YAG rod (1) and the sealing laser pump cavity of pumping with krypton lamp or xenon lamp (2), optionally can cool off in the device by secondary cooling water (using tap water usually) or with compressor for refrigeration in self-loopa and cool off deionized water in the self-loopa water tank.Start the pre-burning that sequential control circuit in the power supply is finished pumping lamp automatically by latching switch, pumping lamp is operated in keeps current status.According to doctor's needs therapy apparatus is preset on the corresponding pumping lamp operating current of required laser power, that exports with red laser diode (9) with indication aims at Optical fibre writing appliance (11) focus that needs treatment with treatment laser with the red laser of light path, step on foot switch, pumping lamp (2) promptly is operated on the required corresponding electric current of laser power of treatment, the light that this moment, pumping lamp sent focuses on the Nd:YAG crystal Nd in the YAG crystal in laser pump cavity 3+In resonator cavity (5) (6), produce the laser of respective wavelength behind the ionic absorption pump light, by condenser lens laser is injected the medical optical fiber that core diameter is 200-600 μ m with the outgoing mirror one, by the Optical fibre writing appliance (11) of aiming at focus with laser irradiation on focus to focus shine, solidify, carbonization, gasification or cutting treatment, optionally Optical fibre writing appliance can be mixed suitable cutter head to cooperate the needs of clinical operation.

Claims (8)

1.一种激光治疗机,包括Nd:YAG晶体;用于泵浦所述晶体以及使所述晶体形成激活离子粒子数反转分布的泵浦系统;以及光学谐振腔,其特征在于:利用Nd:YAG晶体中Nd3+离子4F3/2能级的R2组态到4I13/2能级的X3组态跃迁产生的1338nm辐射,在特殊的光学谐振腔中产生1338nm振荡,并输出1338nm激光,所述波长激光处于医用光纤的透明波长范围内,上述波长激光在人体组织的穿透深度适中。1. A laser treatment machine, comprising Nd:YAG crystal; used to pump the crystal and make the crystal form the pumping system of the reverse distribution of the number of activated ion particles; and optical resonator, it is characterized in that: utilize Nd : The 1338nm radiation generated by the transition from the R 2 configuration of the Nd 3+ ion 4 F 3/2 energy level to the X 3 configuration transition of the 4 I 13/2 energy level in the YAG crystal produces 1338nm oscillation in a special optical resonant cavity, And output 1338nm laser, the wavelength laser is in the transparent wavelength range of medical optical fiber, the penetration depth of the above-mentioned wavelength laser is moderate in human tissue. 2.一种激光治疗机,包括Nd:YAG晶体;用于泵浦所述晶体以及使所述晶体形成激活离子粒子数反转分布的泵浦系统;以及光学谐振腔,其特征在于:利用Nd:YAG晶体中Nd3+离子4F3/2能级的R2组态到4I13/2能级的X1组态和X3组态跃迁产生的1319nm和1338nm辐射,在特殊的光学谐振腔中同时产生1319nm和1338nm振荡,并同时输出1319nm和1338nm双波长激光,所述双波长激光处于医用光纤的透明波长范围内,上述波长激光在人体组织的穿透深度适中。2. A laser therapy machine, comprising Nd:YAG crystals; used to pump the crystals and make the crystals form the pumping system of the reverse distribution of the number of activated ion particles; and an optical resonant cavity, characterized in that: using Nd : The 1319nm and 1338nm radiation produced by the transition from the R 2 configuration of the 4 F 3/2 energy level of the Nd 3+ ion in the YAG crystal to the X 1 configuration and the X 3 configuration of the 4 I 13/2 energy level, in special optical 1319nm and 1338nm oscillations are simultaneously generated in the resonant cavity, and dual-wavelength lasers of 1319nm and 1338nm are simultaneously output. The dual-wavelength lasers are within the transparent wavelength range of medical optical fibers, and the above-mentioned wavelength lasers have a moderate penetration depth in human tissue. 3.如权利要求1或2所述的两种激光治疗机,其特征在于:它们还包括传输1338nm或同时传输1319nm和1338nm双波长激光的医用光纤;将谐振腔输出的相应波长激光会聚到所述医用光纤一端的注入透镜,或将谐振腔输出镜与会聚透镜合二为一的能将输出激光会聚到所述医用光纤一端的谐振腔输出镜;与所述医用光纤另一端相连的将所述相应波长激光照射到所需治疗病灶部位的光纤笔或含有特殊光刀头的光纤笔。3. Two kinds of laser therapy machines as claimed in claim 1 or 2, characterized in that: they also include medical optical fibers that transmit 1338nm or simultaneously transmit 1319nm and 1338nm dual-wavelength lasers; The injection lens at one end of the medical optical fiber, or the resonant cavity output mirror that combines the resonant cavity output mirror and the converging lens to converge the output laser light to one end of the medical optical fiber; the other end of the medical optical fiber is connected to the The above-mentioned corresponding wavelength laser is irradiated to the fiber optic pen or the fiber optic pen with a special optical knife head to the lesion site to be treated. 4.如权利要求1或2所述的两种激光治疗机,其特征在于:它还包括与所述治疗激光同光路指示的半导体激光器,该半导体激光器发出的红色可见激光用于被治疗病灶的指示。4. Two kinds of laser treatment machines as claimed in claim 1 or 2, characterized in that: it also includes a semiconductor laser with the same optical path as the treatment laser, and the visible red laser emitted by the semiconductor laser is used for the treatment of lesions. instruct. 5.如权利要求1或2所述的激光治疗机,其特征在于:泵浦系统的泵浦源包括能连续改变输入功率或能量的连续、脉冲或重复率脉冲驱动源和作为泵浦灯的氪灯或氙灯。5. The laser treatment machine as claimed in claim 1 or 2, characterized in that: the pumping source of the pumping system includes a continuous, pulsed or repetition rate pulsed driving source that can continuously change input power or energy and a pumping lamp Krypton or Xenon lamps. 6.如权利要求1或2所述的两种激光治疗机,其特征在于:包括调Q和锁模元件,产生ns和ps的调Q和锁模激光。6. Two kinds of laser treatment machines as claimed in claim 1 or 2, characterized in that: it includes Q-switching and mode-locking components to generate ns and ps Q-switching and mode-locking lasers. 7.如权利要求5所述的两种激光治疗机,其特征在于:所述泵浦系统的泵浦源为激光二极管及其驱动源。7. The two kinds of laser therapy machines according to claim 5, characterized in that: the pumping source of the pumping system is a laser diode and its driving source. 8.如权利要求1或2所述的激光治疗机,其特征在于:它还包括所述激光装置的冷却系统。8. The laser treatment machine according to claim 1 or 2, characterized in that it further comprises a cooling system for the laser device.
CNB00103958XA 2000-03-16 2000-03-16 laser therapy machine Expired - Fee Related CN1139366C (en)

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