CN113925895A - Traditional Chinese medicine composition for treating acute and chronic rhinitis, oral preparation and preparation method thereof - Google Patents
Traditional Chinese medicine composition for treating acute and chronic rhinitis, oral preparation and preparation method thereof Download PDFInfo
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/483—Gleditsia (locust)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/532—Agastache, e.g. giant hyssop
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/534—Mentha (mint)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/538—Schizonepeta
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
- A61K36/575—Magnolia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Abstract
The invention relates to the technical field of traditional Chinese medicines, and particularly discloses a traditional Chinese medicine composition for treating acute and chronic rhinitis, which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-30 parts of angelica dahurica, 10-30 parts of ageratum, 10-30 parts of cocklebur fruit, 10-30 parts of centipeda minima, 10-30 parts of ligusticum wallichii, 10-30 parts of magnolia flower, 10-30 parts of schizonepeta, 10-30 parts of liquorice, 5-10 parts of gleditsia sinensis and 5-10 parts of mint. Through the verification of patients taking the traditional Chinese medicine composition for treating acute and chronic rhinitis for many years, the traditional Chinese medicine composition has an obvious curative effect on acute and chronic intractable rhinitis, the cure rate reaches more than 98%, relapse does not occur after cure, and adverse reactions are not found in the clinical process. The formula of the traditional Chinese medicine composition adopts natural Chinese herbal medicine raw materials, has simple preparation process, stable formula without toxic and side effects, convenient use and contribution to popularization, and can meet the medication requirements of a large number of rhinitis patients.
Description
Technical Field
The invention belongs to the technical field of traditional Chinese medicines, and particularly relates to a traditional Chinese medicine composition for treating acute and chronic rhinitis, an oral preparation and preparation thereof.
Background
Rhinitis, an inflammatory disease of the nasal cavity, is inflammation of the mucous membrane of the nasal cavity caused by viruses, bacteria, allergens, various physicochemical factors and certain systemic diseases. Rhinitis is classified into: acute rhinitis, chronic rhinitis, allergic rhinitis, rhinitis medicamentosa, and the like. Acute rhinitis is mainly manifested by nasal obstruction, sneezing, watery nasal discharge, fever, aversion to wind, headache, etc. Chronic rhinitis is characterized by lasting course for more than a few months or repeated attack, failure to recover to normal in intermittent periods, nasal obstruction, continuous running nose, moderate nasal noise, swelling mucous membrane, increased secretion, no clear pathogenic microorganism infection and the like. Chronic rhinitis is a common clinical disease, greatly affects daily life and work of many patients, and requires early treatment. At present, the clinical treatment mainly adopts methods such as drug treatment, surgical treatment, laser treatment, electric ironing and the like, the drug treatment has the advantages of strong pertinence and quick response, but has certain side effect, the symptoms and root causes are not treated, the recurrence is easy after the drug is stopped, the surgical treatment mainly takes the damage to the physiological structure as the cost, the curative effect is obviously improved compared with the past, and the long-term curative effect is not satisfactory enough.
The acute rhinitis is characterized by common cold nasal obstruction, nasal asphyxia, stroke, cold, common cold and the like in ancient medical books, the differentiation of the common cold nasal obstruction is mainly divided into two types of symptoms of exogenous wind-cold and exogenous wind-heat, the major treatment method of 'pungent dispersing and resuscitation' is adopted, and the methods of benefiting lung, strengthening exterior, relieving exterior, regulating middle warmer, clearing lung, eliminating phlegm, clearing lung and stomach and the like are adopted according to the specific conditions of the disease condition on the basis of the wind-heat and wind-cold symptoms, and meanwhile, the superficial dispersion is not too excessive to avoid dissipating vitality and the like. The traditional Chinese medicine considers that the chronic rhinitis is caused by stagnated heat of lung and yangming meridians, unsmooth qi and blood, deficiency of lung and spleen, deficiency of qi and blood, stasis of qi and blood, obstruction of channels and collaterals and pathogenic factors stagnating nasal orifices. In traditional Chinese medicine, the lung is considered to open into the nose, the lung and the nasal orifice are smooth, the smell is sensitive, if the lung qi is insufficient and the defensive yang is not firm, the lung is easy to be attacked by pathogenic toxin and loses the function of purifying and purifying, so that the spleen and the stomach are damaged, the spleen and the stomach are weak, the transportation and transformation are not healthy, the functions of ascending the clear and descending the turbid are lost, the damp turbidity is retained in the nasal orifice, the venation is blocked, and the qi and blood are unsmooth in running to cause the disease; or the nasal obstruction is caused by the retention of pathogenic toxin in the veins and the inhibition of qi and blood, which is caused by qi stagnation and blood stasis when exogenous pathogenic factors attack the nasal orifice. At present, traditional Chinese medicine treatment for rhinitis mainly adopts traditional Chinese medicine external treatment and traditional Chinese medicine internal treatment, the traditional Chinese medicine external treatment is an external treatment mode that a single traditional Chinese medicine or a compound nasal drop prepared by a compound is used for nasal drops, or powder is directly blown on the surface of nasal mucosa, or ointment is applied to the nose, and the like, the traditional Chinese medicine has the advantages of quick response, temporary symptoms and root causes, easy relapse after stopping the medicine, and the traditional Chinese medicine internal treatment mainly adopts dialectical treatment, can clear heat, diminish inflammation, dispel wind, dredge orifices, is used for treating sneeze, nasal obstruction, headache and the like caused by the rhinitis, and has the characteristics of treating both symptoms and root causes, having obvious curative effect, avoiding side effects of western medicines, and the like. The existing traditional Chinese medicine for treating rhinitis has slow action and poor curative effect, and still cannot meet the medication requirements of patients. The inventor combines the hereditary secret formula and the summary of the experience of the inventor for many years, utilizes the theory of traditional Chinese medicine, and obtains the traditional Chinese medicine composition for treating chronic rhinitis after the verification of taking medicine by patients for more than twenty years, and the traditional Chinese medicine composition has obvious curative effect for treating acute and chronic rhinitis.
Disclosure of Invention
The invention aims to provide a traditional Chinese medicine composition for treating acute and chronic intractable rhinitis, an oral preparation and a preparation method thereof, and overcomes the defects in the prior art.
In order to realize the purpose, the invention provides a traditional Chinese medicine composition for treating acute and chronic rhinitis, which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-30 parts of angelica dahurica, 10-30 parts of ageratum, 10-30 parts of cocklebur fruit, 10-30 parts of centipeda minima, 10-30 parts of ligusticum wallichii, 10-30 parts of magnolia flower, 10-30 parts of schizonepeta, 10-30 parts of liquorice, 5-10 parts of gleditsia sinensis and 5-10 parts of mint.
Preferably, the traditional Chinese medicine composition for treating acute and chronic rhinitis is prepared from the following traditional Chinese medicine raw materials in parts by weight: 22-30 parts of angelica dahurica, 20-28 parts of ageratum, 20-28 parts of cocklebur fruit, 22-30 parts of centipeda minima, 10-20 parts of ligusticum wallichii, 10-20 parts of magnolia flower, 10-20 parts of schizonepeta, 10-18 parts of liquorice, 5-8 parts of gleditsia sinensis and 5-8 parts of mint.
Preferably, the traditional Chinese medicine composition for treating acute and chronic rhinitis is prepared from the following traditional Chinese medicine raw materials in parts by weight: 28 parts of angelica dahurica, 25 parts of ageratum, 25 parts of cocklebur fruit, 28 parts of centipeda minima, 15 parts of ligusticum wallichii, 18 parts of magnolia flower, 15 parts of schizonepeta, 12 parts of liquorice, 6 parts of fructus gleditsiae and 7 parts of mint.
An oral preparation for treating acute and chronic rhinitis comprises the traditional Chinese medicine composition for treating acute and chronic rhinitis.
Preferably, in the oral preparation for treating acute and chronic rhinitis, the oral preparation is oral liquid, capsules, granules or tablets.
A preparation method of the oral preparation for treating acute and chronic rhinitis comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials according to the weight ratio, soaking the raw materials in water which is 5-10 times of the total weight of the raw materials for 30-60 minutes, then boiling the raw materials with strong fire, then decocting the raw materials with slow fire for 40-60 minutes, and filtering the decoction to obtain filtrate and dregs;
(2) adding water which is 3-5 times of the total weight of the medicine residues into the medicine residues again for decoction, decocting the medicine residues for 30-40 minutes by slow fire after the medicine residues are boiled, and filtering to collect filtrate and the medicine residues; decocting the residue once again, and filtering to obtain filtrate;
(3) and combining the filtrates, concentrating until the relative density is 1.1-1.2, and filling into oral liquid.
Preferably, in the preparation method of the oral preparation for treating acute and chronic rhinitis, in the step (3), the further concentration is carried out to obtain thick paste, the thick paste is dried and crushed into fine powder, and the fine powder is mixed with pharmaceutically acceptable auxiliary materials to prepare capsules, granules or tablets.
In the formula of the traditional Chinese medicine composition for treating acute and chronic rhinitis, the radix angelicae is warm in nature and pungent in taste, enters lung, spleen and stomach channels, and has the effects of relieving exterior syndrome, dispelling cold, dispelling wind, relieving pain, dredging nasal orifices, eliminating dampness, stopping leukorrhagia, reducing swelling and expelling pus; ageratum is warm in nature and pungent in taste, and has the effects of invigorating spleen, stomach and lung channels, resolving dampness and enlivening spleen, removing dirt and regulating the middle warmer and relieving exterior syndrome; fructus xanthil is warm in nature and sweet in taste, enters lung and liver channels, and has the effects of dispelling wind and cold, and relieving stuffiness and pain; herba Centipedae, warm in nature, pungent in taste, capable of entering lung and liver meridians, dispelling wind cold, dredging nasal orifice, stopping , and can be used for treating wind cold headache, cough with excessive phlegm, stuffy nose, nasosinusitis and watery nasal discharge; the ligusticum wallichii is warm in nature and pungent in taste, enters the liver, spleen and triple energizer meridians, promotes qi circulation to relieve depression, dispels wind-dryness and dampness, and activates blood to relieve pain; flos Magnoliae, warm in nature and pungent in flavor, enters lung and stomach meridians, can dispel pathogenic wind-cold and pathogenic qi externally, and can ascend to lung and stomach clear qi; schizonepeta tenuifolia is slightly warm in nature and pungent in flavor, enters lung and liver meridians, has the effects of relieving exterior syndrome, dispelling wind and promoting eruption, and is used for treating common cold, headache, measles, rubella and initial stage of pyocutaneous disease; the liquorice has mild nature and sweet taste, and has the effects of invigorating the spleen and replenishing qi, clearing away heat and toxic materials, eliminating phlegm and stopping cough, relieving spasm and pain and harmonizing the medicines in the channels of the heart, the lung, the spleen and the stomach; the Gleditsia sinensis, being warm in nature, pungent and salty in taste, enters lung channel and large intestine channel, and has effects of relieving cough, eliminating phlegm, inducing resuscitation, resolving masses and relieving swelling; the mint is pungent in taste and cool in nature, enters lung and liver meridians, and has the effects of dispelling wind and dissipating heat, refreshing head and eyes, relieving sore throat, promoting eruption and relieving depression.
From the perspective of traditional Chinese medicine, acute rhinitis is caused by external infection of wind-cold, external infection of wind-heat and pathogenic factors stagnating nasal orifices, and the traditional Chinese medicine treats the rhinitis by pungent powder and stuffy nose, and also has the effects of tonifying lung and consolidating exterior, relieving exterior syndrome and regulating the middle warmer, clearing lung and eliminating phlegm, clearing lung and stomach and the like; chronic rhinitis is usually caused by dysfunction of lung, spleen and stomach, deficiency of lung, spleen and kidney, deficiency of qi and blood, stagnation of qi and blood, obstruction of channels and collaterals, and exogenous wind-cold and pathogenic factors obstructing nasal orifices. Treating rhinitis requires treating the root cause, tonifying lung qi, warming kidney and spleen, and strengthening body resistance to consolidate the constitution. In the formula of the traditional Chinese medicine composition for treating acute and chronic rhinitis, the angelica dahurica, the agastache rugosus, the siberian cocklebur fruit and the centipeda minima are monarch drugs, and can warm kidney and spleen, tonify lung qi, ventilate lung and dredge orifices; the hemlock parsley, the magnolia flower and the schizonepeta are used as ministerial medicines and can warm the lung, dispel cold and activate blood to remove obstruction in channels and collaterals, dredge orifices and stop nasal discharge; the liquorice, the Chinese honey locust and the mint are assistant and guide medicines and can warm the internal organs, strengthen the body resistance and harmonize cold and heat, the medicines are compatible, the components are mutually matched and are synergistically promoted, the internal organs are adjusted, the internal organs are warmed, the body resistance is strengthened, the spleen is strengthened, the qi is benefited, simultaneously the lung is warmed, the cold is dispelled, the blood is promoted, the obstruction in channels and collaterals is removed, the orifice is cleared, the nasal discharge is stopped, the effect of treating both symptoms and root causes is achieved, the effect of treating acute and chronic rhinitis is achieved, and the treatment effect is remarkable.
Compared with the prior art, the invention has the following beneficial effects:
through the verification of patients taking the traditional Chinese medicine composition for treating acute and chronic rhinitis for many years, the traditional Chinese medicine composition has an obvious curative effect on acute and chronic intractable rhinitis, the cure rate reaches more than 98%, relapse does not occur after cure, and adverse reactions are not found in the clinical process. The formula of the traditional Chinese medicine composition adopts natural Chinese herbal medicine raw materials, has simple preparation process, stable formula without toxic and side effects, convenient use and contribution to popularization, and can meet the medication requirements of a large number of rhinitis patients.
Detailed Description
The following detailed description of specific embodiments of the invention is provided, but it should be understood that the scope of the invention is not limited to the specific embodiments.
Example 1
A traditional Chinese medicine composition for treating acute and chronic rhinitis is prepared from the following traditional Chinese medicine raw materials in parts by weight: 28 parts of angelica dahurica, 25 parts of ageratum, 25 parts of cocklebur fruit, 28 parts of centipeda minima, 15 parts of ligusticum wallichii, 18 parts of magnolia flower, 15 parts of schizonepeta, 12 parts of liquorice, 6 parts of fructus gleditsiae and 7 parts of mint.
The preparation method of the oral liquid for treating acute and chronic rhinitis comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials according to the weight ratio, soaking the raw materials in water 8 times of the total weight of the raw materials for 30 minutes, then boiling the raw materials with strong fire, then decocting the raw materials with slow fire for 60 minutes, and filtering the decoction to obtain filtrate and dregs;
(2) adding water 4 times of the total weight of the medicinal residues into the medicinal residues again, decocting for 30 minutes with slow fire after boiling, and filtering to collect filtrate and medicinal residues; decocting the residue once again, and filtering to obtain filtrate;
(3) mixing filtrates, concentrating to relative density of 1.2, and packaging to obtain oral liquid.
Example 2
A traditional Chinese medicine composition for treating acute and chronic rhinitis is prepared from the following traditional Chinese medicine raw materials in parts by weight: 25 parts of angelica dahurica, 28 parts of ageratum, 25 parts of cocklebur fruit, 25 parts of centipeda minima, 18 parts of ligusticum wallichii, 15 parts of magnolia flower, 16 parts of schizonepeta, 13 parts of liquorice, 7 parts of fructus gleditsiae and 5 parts of mint.
Example 3
A traditional Chinese medicine composition for treating acute and chronic rhinitis is prepared from the following traditional Chinese medicine raw materials in parts by weight: 28 parts of angelica dahurica, 24 parts of ageratum, 24 parts of cocklebur fruit, 28 parts of centipeda minima, 15 parts of ligusticum wallichii, 15 parts of magnolia flower, 18 parts of schizonepeta, 15 parts of liquorice, 5 parts of gleditsia sinensis lam and 6 parts of mint.
Application example: test of drug efficacy
83 cases of the coadministration treatment are diagnosed as chronic rhinitis patients according to pathological and clinical manifestations, the patients age 16-59 years, the male is 56 cases, and the female is 27 cases. The oral liquid for treating acute and chronic rhinitis, prepared in the embodiment 1 of the invention, is orally taken by a patient for 15g each time, 2 times a day and 15 days as a treatment course. After most patients take the medicine for 5 days, rhinitis symptoms of the patients basically disappear, after the medicine is taken for one treatment course, the rhinitis symptoms of the patients completely disappear, the rhinitis symptoms do not relapse after three to five years of follow-up visit, and the statistical cure rate reaches 98.5 percent.
Typical cases are:
case one: after the oral liquid of the embodiment 1 of the invention is orally taken continuously for 15 days, the symptoms completely disappear, and the disease does not relapse after three follow-up years.
Case two: if Li Yi, women, 18 years old, suffer from chronic rhinitis for 3 years, often have nasal obstruction, thin nasal discharge and sneeze, and are ineffective after being treated by various hospitals and self-purchased medicines for 2 years, the oral liquid of the embodiment 1 of the invention is orally taken for 5 days, the symptoms basically disappear, the oral liquid is continuously taken for 15 days, the chronic rhinitis is completely cured, and the chronic rhinitis does not relapse after two years of follow-up.
Case three: the oral liquid disclosed by the invention is used for treating chronic rhinitis for 2 years, headache and dizziness are caused by male and 35 years old, nasal obstruction is accompanied, the sense of smell is weakened, yellow nasal discharge occurs occasionally, chronic rhinitis is diagnosed, the patient is treated by Chinese and western medicines successively, the symptoms are mild and severe, after the oral liquid disclosed by the invention embodiment 1 is taken for 3 days, the related symptoms are relieved, after the oral liquid is continuously taken for 10 days, the symptoms completely disappear, and then the oral liquid is continuously taken for 5 days, so that the rhinitis symptoms completely disappear and are recovered, and no recurrence occurs in five years.
Case four: some burnt, male, 46 years old, patient's fever because of cold before ten years, nasal obstruction flows clear nasal discharge, through treating and recovering, but then often cold nasal obstruction, flow yellow thick nasal discharge, take "rhinitis well" can relieve temporarily later, but it is not cured for a long time, slow nasal obstruction aggravate, nasal discharge is sticky and thick, the color is yellow and unfavorable, headache dizziness aggravates, the sense of smell declines, the tongue is pale red, the tongue fur is white, diagnose as chronic sinusitis. After the oral liquid of the embodiment 1 of the invention is taken for 5 days, the rhinitis is not improved greatly, and the oral liquid is taken for 10 days, so that the rhinitis symptoms basically disappear, the oral liquid is taken for 10 days again for consolidation, the rhinitis is completely cured, and the rhinitis does not relapse after three years of follow-up.
The foregoing descriptions of specific exemplary embodiments of the present invention have been presented for purposes of illustration and description. It is not intended to limit the invention to the precise form disclosed, and obviously many modifications and variations are possible in light of the above teaching. The exemplary embodiments were chosen and described in order to explain certain principles of the invention and its practical application to enable one skilled in the art to make and use various exemplary embodiments of the invention and various alternatives and modifications as are suited to the particular use contemplated. It is intended that the scope of the invention be defined by the claims and their equivalents.
Claims (7)
1. A traditional Chinese medicine composition for treating acute and chronic rhinitis is characterized by being prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-30 parts of angelica dahurica, 10-30 parts of ageratum, 10-30 parts of cocklebur fruit, 10-30 parts of centipeda minima, 10-30 parts of ligusticum wallichii, 10-30 parts of magnolia flower, 10-30 parts of schizonepeta, 10-30 parts of liquorice, 5-10 parts of gleditsia sinensis and 5-10 parts of mint.
2. The traditional Chinese medicine composition for treating acute and chronic rhinitis according to claim 1, which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 22-30 parts of angelica dahurica, 20-28 parts of ageratum, 20-28 parts of cocklebur fruit, 22-30 parts of centipeda minima, 10-20 parts of ligusticum wallichii, 10-20 parts of magnolia flower, 10-20 parts of schizonepeta, 10-18 parts of liquorice, 5-8 parts of gleditsia sinensis and 5-8 parts of mint.
3. The traditional Chinese medicine composition for treating acute and chronic rhinitis according to claim 2, which is prepared from the following traditional Chinese medicine raw materials in parts by weight: 28 parts of angelica dahurica, 25 parts of ageratum, 25 parts of cocklebur fruit, 28 parts of centipeda minima, 15 parts of ligusticum wallichii, 18 parts of magnolia flower, 15 parts of schizonepeta, 12 parts of liquorice, 6 parts of fructus gleditsiae and 7 parts of mint.
4. An oral preparation for treating acute and chronic rhinitis, which comprises the Chinese medicinal composition for treating acute and chronic rhinitis according to any one of claims 1 to 3.
5. The oral preparation for treating acute and chronic rhinitis according to claim 4, wherein the oral preparation is oral liquid, capsule, granule or tablet.
6. A method for preparing the oral preparation for treating acute and chronic rhinitis according to claim 5, which comprises the following steps:
(1) weighing the traditional Chinese medicine raw materials according to the weight ratio, soaking the raw materials in water which is 5-10 times of the total weight of the raw materials for 30-60 minutes, then boiling the raw materials with strong fire, then decocting the raw materials with slow fire for 40-60 minutes, and filtering the decoction to obtain filtrate and dregs;
(2) adding water which is 3-5 times of the total weight of the medicine residues into the medicine residues again for decoction, decocting the medicine residues for 30-40 minutes by slow fire after the medicine residues are boiled, and filtering to collect filtrate and the medicine residues; decocting the residue once again, and filtering to obtain filtrate;
(3) and combining the filtrates, concentrating until the relative density is 1.1-1.2, and filling into oral liquid.
7. The method for preparing an oral preparation for treating acute and chronic rhinitis according to claim 6, wherein in step (3), the mixture is further concentrated to obtain a thick paste, the thick paste is dried and crushed into fine powder, and the fine powder is mixed with pharmaceutically acceptable auxiliary materials to prepare capsules, granules or tablets.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202111410407.8A CN113925895A (en) | 2021-11-25 | 2021-11-25 | Traditional Chinese medicine composition for treating acute and chronic rhinitis, oral preparation and preparation method thereof |
Applications Claiming Priority (1)
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| CN102247467A (en) * | 2010-05-18 | 2011-11-23 | 汤明昌 | Method for preparing magnolia flower rhinitis-treating pills |
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| CN102247467A (en) * | 2010-05-18 | 2011-11-23 | 汤明昌 | Method for preparing magnolia flower rhinitis-treating pills |
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| Title |
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| 刘飞: "中西医结合治疗老年慢性鼻窦炎30例", 《中国老年学杂志》 * |
| 彭涛等: "辛夷鼻炎丸治疗急、慢性鼻炎及变应性鼻炎多中心随机对照试验", 《中国医药指南》 * |
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