CN113876322A - Reflection type blood oxygen detection device - Google Patents

Reflection type blood oxygen detection device Download PDF

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Publication number
CN113876322A
CN113876322A CN202111402703.3A CN202111402703A CN113876322A CN 113876322 A CN113876322 A CN 113876322A CN 202111402703 A CN202111402703 A CN 202111402703A CN 113876322 A CN113876322 A CN 113876322A
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processing module
blood oxygen
module
data
control processing
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何超鑫
徐奕鸿
李瑾慧
潘涛
钟依萍
徐远胜
周雪芳
杨国伟
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Hangzhou Dianzi University
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/1455Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters
    • A61B5/14551Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue using optical sensors, e.g. spectral photometrical oximeters for measuring blood gases
    • A61B5/14552Details of sensors specially adapted therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/0205Simultaneously evaluating both cardiovascular conditions and different types of body conditions, e.g. heart and respiratory condition
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02416Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/024Detecting, measuring or recording pulse rate or heart rate
    • A61B5/02416Detecting, measuring or recording pulse rate or heart rate using photoplethysmograph signals, e.g. generated by infrared radiation
    • A61B5/02427Details of sensor
    • A61B5/02433Details of sensor for infrared radiation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/145Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue
    • A61B5/14542Measuring characteristics of blood in vivo, e.g. gas concentration, pH value; Measuring characteristics of body fluids or tissues, e.g. interstitial fluid, cerebral tissue for measuring blood gases

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  • Spectroscopy & Molecular Physics (AREA)
  • Pulmonology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)

Abstract

The invention discloses a reflection type blood oxygen detection device, which comprises a signal acquisition module, a signal processing module, a control processing module and a display module; the signal acquisition module: collecting pulse signals and outputting the pulse signals to a signal processing module; the signal processing module: the device is used for eliminating ambient light, converting photoelectric signals, digitally filtering, storing data and outputting the data to the control processing module; the control processing module: analyzing and calculating the signals, and sending the result obtained by calculation to a display module; a display module: used for displaying the detection result. The transmission type detection instrument solves the problem that a transmission type detection instrument cannot accurately detect when a user is smeared with nail polish and suffers from onychomycosis or the tail end is poor in blood circulation, can detect the blood oxygen saturation in real time, and has the advantages of being simple in structure, convenient to operate, low in cost, high in detection precision and the like, and the market application prospect is wide.

Description

Reflection type blood oxygen detection device
Technical Field
The invention belongs to the technical field of medical appliance manufacturing, and particularly relates to a reflection type blood oxygen detection device which can detect the blood oxygen saturation and the heart rate value in real time, in particular to the blood oxygen saturation detection of a shock patient.
Background
The design of the pulse oximeter is based on the Lambert beer law and the optical colorimetry principle, the absorption amount of oxyhemoglobin and reduced hemoglobin in blood to 660nm wavelength red light and 880nm wavelength infrared light is in direct proportion to the concentration and the blood volume, the blood oxygen volume can be changed the same when the pulse fluctuates, two LED light sources are made to alternately irradiate a tested part, the light intensity of transmitted light is detected by MAX30102, the concentrations of oxyhemoglobin and reduced hemoglobin in blood can be calculated due to the same changed volumes, and therefore the blood oxygen saturation is calculated. The pulse oximeter is a medical appliance for monitoring the blood oxygen saturation of human artery without wound.
Most pulse oximeters in the market at present adopt a transmission detection principle, namely a finger clip oximeter, and the oximeter has certain defects in clinical use, such as that the measurement part is limited to fingertips and earlobes, and if a patient is smeared with nail polish, the patient suffers from onychomycosis or the tail end cannot carry out accurate measurement when the blood circulation is not smooth. And blood oxygen detection device based on reflection principle is mainly the motion bracelet on the market at present, but the motion bracelet exists detection data not accurate enough, uses defects such as convenient inadequately.
At present, the blood oxygen saturation detection of shock patients in medical science is invasive detection, so that the body of the patient is wounded, and the time for acquiring data is long.
Disclosure of Invention
Aiming at the defects of the existing blood oxygen saturation detection device, the invention discloses a reflection type blood oxygen detection device which is combined with the reflection type blood oxygen detection principle and can accurately measure the blood oxygen saturation and the heart rate of healthy people and shock patients.
In order to realize the purpose, the invention adopts the following technical scheme:
a reflection type blood oxygen detection device comprises a signal acquisition module, a signal processing module, a control processing module and a display module;
the signal acquisition module: collecting pulse signals and outputting the pulse signals to a signal processing module;
the signal processing module: the device is used for eliminating ambient light, converting photoelectric signals, digitally filtering, storing data and outputting the data to the control processing module;
the control processing module: analyzing and calculating signals, wherein the specific steps comprise carrying out scale conversion, solving the mean value, judging and discarding data, calculating by using an empirical formula, finally taking the mean value of a plurality of calculation results, and sending the result obtained by calculation to a display module;
a display module: used for displaying the detection result.
Preferably, the signal acquisition module is composed of two LED lamps with different wavelengths and a photodiode for detecting reflected light, and the two LED lamps with different wavelengths respectively emit red light and infrared light; the photodiode inputs a signal to the signal processing module.
Preferably, the red light LED and the infrared light LED are respectively connected to the LED driver in the signal processing module.
Preferably, the signal processing module selects MAX 30102.
Preferably, the control processing module adopts a chip ESP _ WROOM _ 32; an SDA interface used for data transmission of the signal processing module MAX30102 is connected with a data input interface IO18 of a control processing module ESP 32; the clock input SCL interface of the signal processing module is connected to interface IO19 of control processing module ESP 32.
Preferably, the data transmission interface SDA of the display module is connected to the data output interface IO21 of the control processing module ESP 32; the clock input SCL interface of the display module is connected to interface IO22 of control processing module ESP 32.
In the invention, a red light LED with 660nm wavelength and an infrared light LED with 880nm wavelength are respectively incident to a detected part, a photodiode which can detect visible light and infrared light in a sensor can detect an optical signal reflected by human skeleton, and then an internal tracking and holding circuit of an environment light elimination module is used for eliminating environment light, so that the measurement accuracy is improved and the effective measurement dynamic range is increased; and then, carrying out analog-to-digital conversion on the signal by a sigma-delta analog-to-digital converter arranged in the sensor, inputting the processed electric signal into a proprietary programmable full-scale range discrete digital filter in a circuit, filtering and inputting the electric signal into a data register. Because the element receiving the optical signal is relatively insensitive to infrared light, a temperature sensor is arranged in the sensor (in figure 2, the function of eliminating an ADC behind the ambient light is to perform analog-to-digital conversion on a tested photoelectric signal and store the photoelectric signal in a register, the ADC behind the temperature sensor performs analog-to-digital conversion on data tested to the ambient temperature by the temperature sensor, the two paths of signals are stored in the register, an algorithm is used for processing the two paths of data in the register so as to compensate the influence of the change of the ambient temperature on the testing accuracy), the data after the ambient temperature is measured by the temperature sensor is subjected to analog-to-digital conversion by the ADC, the processed data is also input into a data register, the temperature signal and the red light signal are used together, and a related algorithm can compensate the error of the environment temperature change on infrared light measurement, so that the accuracy of measurement data is further improved.
After the data is processed, a bidirectional data transmission interface SDA on the MAX30102 is increased to be connected with a G18 interface of an ESP32 chip, so that the data is transmitted to a control processing module, values of blood oxygen saturation and heart rate are obtained after the data is analyzed and calculated, and finally the data is transmitted to a display module through a data transmission interface to be displayed, so that pulse wave changes can be observed in real time.
Preferably, the data can be input into the WeChat applet "Flat peach" to get the personal health report.
Compared with the prior art, the invention has the beneficial effects that:
1) the invention can realize the measurement of non-fingertip and earlobe parts, and the measurement part is not limited.
2) The invention can realize accurate measurement of the blood oxygen saturation under the special conditions that a user is smeared with nail polish, suffers from onychomycosis, poor blood circulation at the tail end and the like. The existing popular finger-clipped oximeter based on the transmission-type measurement principle is characterized in that red light and infrared light are incident to the finger abdomen and then need to be detected, and because light-absorbing substances such as the black nails and nail polish can absorb a part of light when the nails are affected, the measured data can be inaccurate. If the blood circulation at the tail end of the user is poor, the finger clip type detector can press the blood vessel of the finger, so that the blood volume change caused by the originally weak pulse fluctuation is weaker, the detection cannot be realized, and the accurate measurement cannot be carried out.
3) The device has simple structure and low manufacturing cost, can generate a corresponding health report, and is particularly suitable for people who have the requirement of detecting the blood oxygen saturation in daily life, such as the old, people working in plateau life, workers in closed environment and the like.
Drawings
The invention is further illustrated with reference to the following figures and examples.
FIG. 1 is a block diagram of the system modules of the present invention.
FIG. 2 is a schematic circuit diagram of a reflective blood oxygen detection device according to a preferred embodiment of the present invention.
FIG. 3 is a comparison diagram of the reflection detection principle and the transmission detection principle adopted by the reflection blood oxygen detection device of the present invention, when the transmission measurement principle is used, the measurement location is only limited to the finger and the earlobe, but the measurement location of the reflection measurement principle adopted by the present invention is not limited.
FIG. 4 is a comparison curve of measured data between a reflection type blood oxygen detecting device and a medical pulse blood oxygen detecting device according to the present invention.
FIG. 5 is a partial sectional view of a WeChat applet of a reflectance blood oxygen detection device in accordance with a preferred embodiment of the present invention.
Fig. 6 is a schematic diagram of a signal acquisition module and a signal processing module of a reflective blood oxygen detection device according to a preferred embodiment of the present invention, which is operated by driving red and infrared LED lamps to be respectively incident on the body surface of a subject by an LED driver, detecting light reflected from bones of the human body by a photodiode, eliminating ambient light, performing digital filtering operation, inputting the light into a data register, and outputting data by a data transmission interface.
Fig. 7 is a schematic circuit diagram of a control processing module of a reflective blood oxygen detecting device according to a preferred embodiment of the present invention, wherein IO22 and IO19 interfaces are respectively connected to a sensor MAX30102 and a clock input interface SCL of an OLED display screen, an IO18 interface is connected to a data transmission interface SDA of the MAX30102, and an IO21 interface is connected to an OLED data transmission interface SDA.
Detailed Description
The invention will be described in further detail below with reference to the drawings and preferred embodiments, but the examples should not be construed as limiting the invention.
Referring to fig. 1 to 7, the reflective blood oxygen detection device of the present embodiment is designed based on lambert beer's law, and includes a signal acquisition module, a signal processing module, a control processing module, a display module, and a power supply, where the power supply supplies power to each module, and each module specifically includes:
the signal acquisition module consists of two LED lamps with different wavelengths and a photodiode for detecting the intensity of reflected light, and the two LED lamps with different wavelengths can respectively emit red light and infrared light; the signal acquisition module has the function of acquiring the pulse signals. The signal acquisition module is connected with the signal processing module. Specifically, the red light LED and the infrared light LED are respectively connected to an LED driver in the signal processing module, and the LED driver works at the working frequency provided by the oscillator and simultaneously worksThe oscillator provides the same working frequency for the LED driver and the signal processing module, and the whole circuit is ensured to work under the same frequency. The LED driver can convert the externally input current into a current range of 0-50mA which is suitable for the LED lamp to work, meanwhile, the pulse width of the LED can be adjusted within 69-411 mus, and the photodiode inputs signals to the signal processing module. The signal processing module selects MAX30102, the functions mainly comprise ambient light elimination, photoelectric signal conversion, digital filtering, data storage and the like, and ambient light elimination processing is firstly carried out on signals input by the photodiode. After analog-to-digital conversion, obtaining a digital signal, and after the digital signal passes through a digital filter and a data register, according to I2And C, transmitting the communication protocol to the control processing module. Referring to fig. 6, MAX30102 is a schematic diagram. An SDA interface used for data transmission of the signal processing module MAX30102 is connected with a data input interface IO18 (namely G18) of the control processing module ESP 32; the clock input SCL interface of the signal processing module is connected to the interface IO19 (i.e. G19) of the control processing module ESP 32.
The control processing module selects ESP32, and its function mainly is to analyze and calculate the processed signal, firstly store the input data in the register of ESP32, and take six data each time and store them in six variables, wherein three hexadecimal data are used as a group of decimal data signals, and store the obtained decimal signals, and calculate the mean value of the data stored each time and the stored three groups of data, and then move the calculated mean value forward one bit in turn, and the data with the longest time will be discarded. Discarding the data if the data exceeds or is lower than the critical value after every data detection, obtaining the corresponding AC and DC red light and infrared light values of the data by performing the operation for four times, discarding the data when the data exceeds the critical condition, and otherwise, using a formula
Figure BDA0003371655290000061
Calculating the initial value of the blood oxygen saturation, collecting four groups of final data, and calculating the arithmetic mean value to output. And then the data is stored and transmitted, and the data is sent to a display module for display. Referring to fig. 7, the present invention adopts a domestic chip ESP _ WROOM _32, reducing the number of generationsThe production cost.
The display module OLED is connected to the control module ESP32 for displaying the detection result. The data transmission interface SDA of the display module OLED is connected to the data output interface IO21 (i.e. G21) of the control processing module ESP 32; the clock input SCL interface of the display module is connected to interface IO22 (i.e. G22) of ESP 32.
Fig. 3 shows the comparison between the reflection detection principle and the transmission detection principle adopted by the blood oxygen detecting device of the reflective type of the present invention, in which the measuring part is only limited to the finger and the earlobe, but the present invention is designed based on the reflection detection principle, and when in use, the measuring part (not limited to the finger tip) is placed on the sensor emitting red light and infrared light, and the measuring data can be seen on the display module. The measuring position of the reflection type measuring principle adopted by the invention is not limited.
Referring to fig. 4, the detection data of the present invention is very close to the detection data obtained by the medical instrument, which shows that the present invention has high measurement accuracy.
The measurement result of this embodiment can also be obtained by inputting the measurement data into the mobile phone applet "flat peach" to obtain a personal health report, or by inputting the measurement data into the wechat applet "flat peach" developed based on this device to obtain a personal health report. Referring to fig. 5, the WeChat applet makes a sound recommendation when the user health data is abnormal. As shown in fig. 6, a schematic diagram of a signal acquisition module and a signal processing module of the reflective blood oxygen detection device of the present embodiment is shown, and the working principle thereof is that an LED driver drives red light and infrared light LED lamps to respectively enter the body surface of a testee, a photodiode detects light reflected by human bones, the light is input into a data register after the operations of ambient light elimination and digital filtering, and then data is output through a data transmission interface.
As shown in fig. 7, a schematic diagram of a control processing module of the reflective blood oxygen detecting device of this embodiment is shown, wherein the IO22 and the IO19 interface are respectively connected to the sensor MAX30102 and the clock input interface SCL of the OLED display screen, the IO18 interface is connected to the data transmission interface SDA of the MAX30102, and the IO21 interface is connected to the OLED data transmission interface SDA.
The working principle is as follows: the method comprises the steps of irradiating a detected part by light of two different wavelengths emitted by an LED, detecting a reflected optical signal by a photodiode capable of detecting red light and infrared light, eliminating ambient light of the collected optical signal in a signal processing module, converting the optical signal into an electric signal by an analog-to-digital converter, inputting the signal into a data register after digital filtering, and finally transmitting the signal into a control processing module ESP32 through a data transmission interface. The absorption amount of the oxygenated hemoglobin and the reduced hemoglobin to 660nm red light and 880nm infrared light can be obtained by detecting the intensity of reflected light, the lengths of reflection paths of the light in a human body are the same, namely the volumes of substance liquid layers are the same, the unknown amount of the liquid layer volumes can be eliminated by comparing the expression of the absorption amounts of the two wavelengths of light, so that the concentration ratio of the oxygenated hemoglobin and the reduced hemoglobin is obtained, the ratio is substituted into a calculation formula of the blood oxygen saturation, and the value of the blood oxygen saturation can be obtained. And transmitting the calculated data to a display module for display. Meanwhile, a corresponding health report can be generated on the WeChat applet based on the data detected by the user.
The reflection type pulse oxyhemoglobin saturation detection device provided by the invention overcomes the problem that a transmission type detector cannot accurately detect when a user is smeared with nail polish, has onychomycosis or has poor blood circulation at the tail end, can detect the oxyhemoglobin saturation in real time, and has the advantages of simple structure, convenience in operation, low cost, high detection precision and the like, and has a wide market application prospect.
The foregoing has outlined rather broadly the preferred embodiments and principles of the present invention and it will be appreciated that those skilled in the art may devise variations of the present invention that are within the spirit and scope of the appended claims.

Claims (6)

1. A reflection type blood oxygen detection device is characterized by comprising a signal acquisition module, a signal processing module, a control processing module and a display module;
the signal acquisition module: collecting pulse signals and outputting the pulse signals to a signal processing module;
the signal processing module: the device is used for eliminating ambient light, converting photoelectric signals, digitally filtering, storing data and outputting the data to the control processing module;
the control processing module: analyzing and calculating the signals, and sending the result obtained by calculation to a display module;
a display module: used for displaying the detection result.
2. The reflective blood oxygen detecting device of claim 1, wherein: the signal acquisition module consists of two LED lamps with different wavelengths and a photodiode for detecting reflected light, and the two LED lamps with different wavelengths respectively emit red light and infrared light; the photodiode inputs a signal to the signal processing module.
3. The reflective blood oxygen detecting device of claim 1, wherein: the red light LED and the infrared light LED are respectively connected to the LED driver in the signal processing module.
4. The blood oxygen sensor as claimed in any one of claims 1 to 3, wherein: the signal processing module selects MAX 30102.
5. The reflective blood oxygen detecting device according to claim 4, wherein: the control processing module adopts a chip ESP _ WROOM _ 32; an SDA interface used for data transmission of the signal processing module MAX30102 is connected with a data input interface IO18 of a control processing module ESP 32; the clock input SCL interface of the signal processing module is connected to interface IO19 of control processing module ESP 32.
6. The reflective blood oxygen detecting device according to claim 5, wherein: the data transmission interface SDA of the display module is connected with the data output interface IO21 of the control processing module ESP 32; the clock input SCL interface of the display module is connected to interface IO22 of control processing module ESP 32.
CN202111402703.3A 2021-11-24 2021-11-24 Reflection type blood oxygen detection device Pending CN113876322A (en)

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