CN113855220B

CN113855220B - Radio frequency ablation method, system, storage medium and intelligent terminal

Info

Publication number: CN113855220B
Application number: CN202111285242.6A
Authority: CN
Inventors: 李�城; 曾宪龙
Original assignee: Beijing Blade Opto Electronic Technology Development Co ltd
Current assignee: Beijing Blade Opto Electronic Technology Development Co ltd
Priority date: 2021-11-01
Filing date: 2021-11-01
Publication date: 2022-05-24
Anticipated expiration: 2041-11-01
Also published as: CN113855220A

Abstract

The application relates to a radio frequency ablation method, a radio frequency ablation system, a storage medium and an intelligent terminal, which relate to the field of medical instruments, wherein the method comprises the steps of obtaining information of a current treatment area; determining extension range information; determining propulsion distance information; extending the radio frequency central electrode into the treatment area and advancing according to the advancing distance information to expand the radio frequency sub-electrodes; acquiring electrode temperature information and cell temperature information; calculating temperature difference information; determining current power information; the radio frequency transmitter outputs power to the radio frequency central electrode according to current power information and raises the temperature of the radio frequency central electrode and the radio frequency sub-electrode so as to melt the cancerous cells in the treatment area, so that the problems of quicker temperature rise process and small treatment range are solved.

Description

Radio frequency ablation method, system, storage medium and intelligent terminal

Technical Field

The present application relates to the field of medical devices, and in particular, to a radio frequency ablation method, a radio frequency ablation system, a storage medium, and an intelligent terminal.

Background

With the development of modern medical technology, minimally invasive therapy has become a technological means with the widest development prospect in the field of tumor therapy. At present, the tumor minimally invasive treatment technology represented by radio frequency ablation is playing an increasingly important role in the field of minimally invasive treatment for local solid tumors such as liver cancer, lung cancer and the like.

The principle of the radio frequency ablation is that alternating high-frequency current with the frequency less than 30MHz (generally 460-480 kHz) is applied to enable ions in tumor tissues to generate high-speed oscillation and mutual friction, radio frequency energy is converted into heat energy, and therefore coagulative necrosis of tumor cells occurs. In radiofrequency ablation therapy, the instrument used is a radiofrequency ablation catheter, which is connected to a radiofrequency generator. Under the guidance of B-mode ultrasound or CT, a central electrode at the far end of the radio-frequency ablation catheter is punctured percutaneously, penetrates into a target tumor through a puncture point, and transmits radio-frequency energy to cell tissues around the penetrated part, so that tumor cells contacted by the central electrode are coagulated, denatured and necrotized.

In view of the above-mentioned related technologies, the inventor believes that the temperature rise process is faster, the treatment range is small, and there is room for improvement because the power is not changed during the ablation process.

Disclosure of Invention

In order to solve the problems that the temperature rise process is fast and the treatment range is small due to the fact that power cannot be changed in the ablation process, the radio frequency ablation method, the radio frequency ablation system, the storage medium and the intelligent terminal are provided.

In a first aspect, the present application provides a radio frequency ablation method, which adopts the following technical scheme:

a method of radio frequency ablation comprising:

acquiring current treatment area information;

performing matching analysis according to the expansion range stored in the preset distance database and the current treatment area information to determine the expansion range of the radio frequency sub-electrode required by the current treatment area, and defining the expansion range of the required radio frequency sub-electrode as expansion range information;

performing matching analysis according to the propelling distance and the expansion range information stored in the preset distance conversion database to determine the propelling distance corresponding to the expansion range information, and defining the propelling distance corresponding to the expansion range information as propelling distance information;

extending the radio frequency central electrode into the treatment area and advancing according to the advancing distance information to expand the radio frequency sub-electrodes;

acquiring electrode temperature information of a front terminal electrode of a radio frequency central electrode and cell temperature information corresponding to current treatment area information;

calculating temperature difference information according to the electrode temperature information and the cell temperature information;

performing matching analysis according to the current power and the temperature difference information stored in the preset temperature control database to determine the current power corresponding to the temperature difference information, and defining the current power corresponding to the temperature difference information as the current power information;

the radio frequency transmitter outputs power to the radio frequency central electrode according to the current power information and raises the temperature of the radio frequency central electrode and the radio frequency sub-electrodes so as to ablate the cancer cells in the treatment area.

By adopting the technical scheme, the size of the treatment area is matched with the range of heat emitted by the radio-frequency electrode, so that the treatment range of the radio-frequency ablation system is maximum under the condition that normal cells are not influenced, and the cancerous cells in the area influenced by the radio-frequency central electrode and the radio-frequency sub-electrode are not easy to carbonize by controlling the temperature change, thereby improving the treatment effect.

Optionally, the method for increasing the temperature of the radio frequency central electrode and the radio frequency sub-electrode comprises:

acquiring the highest treatment temperature information;

calculating the temperature difference between the electrode temperature information and the temperature value corresponding to the highest treatment temperature information, and defining the temperature difference as temperature control difference information;

judging whether the temperature difference corresponding to the temperature control difference information is a positive value or not;

if the difference value is a positive value, judging whether the difference value corresponding to the temperature control difference value information falls into a preset temperature difference range;

if the current power falls into the preset temperature difference range, outputting the current power according to the current power information;

if the temperature difference does not fall into the preset temperature difference range, the display sends preset auditory prompting information and state display information, and the radio frequency transmitter automatically cuts off the output;

and if the current power is not a positive value, outputting according to the current power information.

By adopting the technical scheme, when the treatment temperature is higher than the value of the highest treatment temperature information and exceeds a certain range, the system automatically cuts off the output and warns medical personnel to early warn treatment errors, so that the treatment process is safer, and the safety and the stability of the radiofrequency ablation system for ablating cancerous cells are improved.

Optionally, the temperature control method if the difference corresponding to the temperature control difference information falls within the preset temperature difference range includes:

acquiring saline temperature information of physiological saline;

calculating according to the brine temperature information and the electrode temperature information to determine brine temperature difference information;

performing matching analysis according to the flow rate of the physiological saline stored in the preset cooling database and the saline temperature difference information to determine the physiological saline flow rate corresponding to the saline temperature difference information, and defining the physiological saline flow rate corresponding to the saline temperature difference information as flow rate information;

judging whether the flow velocity information is larger than preset safe flow velocity information or not;

if the flow rate information is larger than the preset safe flow rate information, inputting the physiological saline from a guide pipe in the radio frequency transmitter according to the safe flow rate information;

if the flow rate information is less than the preset safe flow rate information, inputting the physiological saline from a guide pipe in the radio frequency transmitter according to the flow rate information;

acquiring input time information of the physiological saline;

calculating according to the flow rate information and the input time information to determine the input amount of the physiological saline, and defining the input amount as flow information;

comparing the physiological saline input quantity corresponding to the flow information with the preset safe input quantity;

if the input amount of the physiological saline corresponding to the flow information is equal to the preset safe input amount, the physiological saline is not input;

and if the physiological saline input amount corresponding to the flow information is smaller than the preset safe input amount, inputting the physiological saline from a guide pipe in the radio frequency transmitter.

By adopting the technical scheme, the physiological saline can clean the inactivated cancer cells on one hand, and on the other hand, when the temperature is in the highest treatment temperature information and the limit range, the end part of the electrode can be cooled, so that the treatment effect is the best under the state of the highest treatment temperature by controlling the temperature, and the control stability of the treatment temperature is improved.

Optionally, the control method of the radio frequency ablation comprises:

acquiring current time length information of power output by a radio frequency transmitter to a radio frequency central electrode;

performing matching analysis according to the corresponding treatment duration and the current treatment area information in the preset treatment duration database to determine and obtain treatment time information of the output power of the radio frequency transmitter to the radio frequency central electrode;

comparing the current duration information with the treatment time information;

if the time length corresponding to the current time length information is equal to the time length corresponding to the treatment time information, the radio frequency transmitter automatically cuts off the output;

and if the duration corresponding to the current duration information is less than the duration corresponding to the treatment time information, the radio frequency transmitter continues to work.

By adopting the technical scheme, the treatment duration is controlled through the size of the canceration area, so that the ablation process is not too short to achieve the ablation effect, the energy is not too long to waste, and the ablation efficiency of the radio-frequency electrode is improved.

Optionally, the method of extending the radio frequency center electrode into the treatment region comprises:

calculating current treatment center information according to the current treatment area information;

acquiring front terminal positioning information of a radio frequency central electrode extending into a treatment area;

judging whether the coordinate point of the front terminal positioning information is overlapped with the coordinate point corresponding to the current treatment center information;

if the coordinate point of the front terminal positioning information is coincident with the coordinate point corresponding to the current treatment center information, the radio frequency transmitter outputs power to the radio frequency central electrode according to the current power information and raises the temperature of the radio frequency central electrode and the radio frequency sub-electrode so as to ablate the cancerous cells in the treatment area;

if the coordinate point of the front terminal positioning information is not coincident with the coordinate point corresponding to the current treatment center information, acquiring front terminal temperature information and outdoor normal temperature information corresponding to the front terminal positioning information;

comparing the temperature value corresponding to the temperature information of the front terminal with the normal temperature information;

if the temperature value corresponding to the temperature information of the front terminal is equal to the normal temperature information, adjusting the positioning information of the front terminal to enable the positioning information of the front terminal to be overlapped with a coordinate point corresponding to the current treatment center information, outputting power to the radio frequency central electrode by the radio frequency transmitter according to the current power information, and increasing the temperature of the radio frequency central electrode and the radio frequency sub-electrode so as to melt the cancerous cells in the treatment area;

if the temperature value corresponding to the front terminal temperature information is larger than the normal temperature information, the display sends preset auditory prompting information and state display information, and the radio frequency transmitter automatically cuts off output.

By adopting the technical scheme, the radio frequency central electrode only starts to work when the front terminal of the radio frequency central electrode reaches the coordinate point corresponding to the current treatment center information, so that the radio frequency central electrode is prevented from being touched by mistake before working, and the radio frequency central electrode is prevented from falling off after working, and the stability of the radio frequency ablation system is improved.

Optionally, the method for determining the coordinate point of the front terminal positioning information includes:

acquiring current thermal induction temperature information;

marking coordinate points with the same current thermal induction temperature information on an electronic map, connecting lines to determine thermal induction temperature rings with the same temperature, and defining the thermal induction temperature rings as the same temperature ring information;

and calculating the center of a thermal induction temperature ring at the same temperature according to the same temperature ring information, and defining the center of a circle as a coordinate point of the front terminal positioning information.

By adopting the technical scheme, because a large number of radio frequency sub-electrodes exist, the front terminal positioning information cannot be identified in the corresponding CT or B-ultrasonic image by naked eyes in the working process, and the temperature of the radio frequency central electrode is higher than that of the surrounding radio frequency sub-electrodes, so that the presented temperature is diffused radially towards the periphery by the radio frequency central electrode, the front terminal is determined by calculating the circle center, the front terminal is accurately positioned, and the positioning efficiency of the front terminal is improved.

Optionally, current impedance information on the radio frequency central electrode is acquired;

judging whether the current impedance information is a preset initial value or not;

if the current impedance information is not the preset initial value, judging whether the time length corresponding to the current time length information is less than the preset no-treatment-effect time length information or not;

if the time length corresponding to the current time length information is longer than the preset time length information without treatment effect, the radio frequency sub-electrode retracts into the guide pin and the radio frequency central electrode normally exits;

judging whether the temperature corresponding to the electrode temperature information is consistent with the highest treatment temperature information or not;

if the radio frequency sub-electrodes are consistent, the radio frequency sub-electrodes retract into the guide pins and the radio frequency central electrode normally exits;

if the time length corresponding to the current time length information is less than the preset time length information without treatment effect or the temperature corresponding to the electrode temperature information is not consistent with the highest treatment temperature information, the radio frequency generator sends the preset needle channel electrocoagulation information to the radio frequency central electrode to carry out electrocoagulation on the cells.

By adopting the technical scheme, because the treatment time is not up or the treatment temperature is not up, the blood is not coagulated, the bleeding phenomenon is easy to occur, whether the electrocoagulation is needed or not is determined by judging the time and the temperature when the needle is withdrawn, the abnormal outflow of the blood is prevented, and the safety of the treatment ablation is improved.

In a second aspect, the present application provides a radio frequency ablation system, which adopts the following technical solutions:

a radio frequency ablation system comprising:

the information acquisition module is used for acquiring the current treatment area information;

the processing module is connected with the information acquisition module and is used for storing and processing the information;

the processing module performs matching analysis according to the expansion range stored in the preset distance database and the current treatment area information to determine the expansion range of the radio frequency sub-electrode required by the current treatment area, and defines the expansion range as expansion range information;

the processing module performs matching analysis according to the propelling distance and the expansion range information stored in the preset distance conversion database to determine the propelling distance corresponding to the expansion range information, and defines the propelling distance corresponding to the expansion range information as propelling distance information;

the processing module extends the radio frequency central electrode into the treatment area and advances the radio frequency central electrode according to the advancing distance information so as to expand the radio frequency sub-electrodes;

the information acquisition module acquires electrode temperature information of a front terminal electrode of the radio frequency central electrode and cell temperature information corresponding to current treatment area information;

the processing module calculates temperature difference information according to the electrode temperature information and the cell temperature information;

the processing module performs matching analysis according to the current power and the temperature difference information stored in the preset temperature control database to determine the current power corresponding to the temperature difference information, and defines the current power corresponding to the temperature difference information as the current power information;

the processing module controls the radio frequency transmitter to output power to the radio frequency central electrode according to the current power information and raises the temperature of the radio frequency central electrode and the radio frequency sub-electrodes so as to ablate the cancerous cells in the treatment area.

In a third aspect, the present application provides an intelligent terminal, which adopts the following technical scheme:

an intelligent terminal comprises a memory and a processor, wherein the memory stores a computer program which can be loaded by the processor and executes any one of the radio frequency ablation methods.

In a fourth aspect, the present application provides a computer-readable storage medium capable of storing a corresponding program, and having features that facilitate efficient long-distance detection.

A computer readable storage medium adopts the following technical scheme:

a computer readable storage medium storing a computer program that can be loaded by a processor and executed to perform any of the rf ablation methods described above.

In summary, the present application includes at least one of the following beneficial technical effects:

the treatment range is enlarged by adjusting the range of heat emitted by the radio-frequency electrode, and the ablated cancer cells are not easy to carbonize by controlling the temperature change, so that the treatment effect is improved;

the physiological saline is arranged to clean the inactivated cancer cells, and the end parts of the electrodes can be cooled, so that the control stability of the treatment temperature is improved;

when the needle is withdrawn, whether the electric coagulation is needed or not is determined by judging the time length and the temperature, and the abnormal outflow of blood is prevented, so that the safety of treatment and ablation is improved.

Drawings

Fig. 1 is a flow chart of a method of radiofrequency ablation in an embodiment of the present application.

Fig. 2 is a schematic structural diagram of a radio frequency ablation device in an embodiment of the present application.

Fig. 3 is a flow chart of a method for increasing the temperature of the rf center electrode and the rf sub-electrode in an embodiment of the present application.

Fig. 4 is a flowchart of a temperature control method in the embodiment of the present application.

Fig. 5 is a flowchart of a control method of radio frequency ablation in an embodiment of the present application.

Figure 6 is a flow chart of a method of extending a radio frequency center electrode into a treatment region in an embodiment of the present application.

Fig. 7 is a flowchart of a determination method of a coordinate point of front terminal positioning information in the embodiment of the present application.

FIG. 8 is a flow chart of an electrocoagulation method after treatment is initiated in an embodiment of the application.

Fig. 9 is a block diagram of a method of radiofrequency ablation in an embodiment of the present application.

Detailed Description

In order to make the objects, technical solutions and advantages of the present application more clearly understood, the present application is further described in detail below with reference to the accompanying fig. 1-9 and the embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the present application and are not intended to limit the present application.

The embodiments of the present invention will be described in further detail with reference to the drawings attached hereto.

Referring to fig. 1, an embodiment of the present invention provides a radio frequency ablation method, and a main flow of the radio frequency ablation method is described as follows:

step 100: current treatment region information is acquired.

The current treatment region information is the region of cancerous cells that need to be ablated, and the acquisition may be by any medical acquisition means, such as CT, B-mode, etc. The purpose of the acquisition is to determine the region of action of the radiofrequency tumor ablation.

Step 101: and performing matching analysis according to the expansion range stored in the preset distance database and the current treatment area information to determine the expansion range of the radio frequency sub-electrode required by the current treatment area, and defining the expansion range as expansion range information.

The expansion range information is the range of the spherical shape formed after the radio frequency sub-electrode is expanded. Referring to fig. 2, the radio frequency emitter is extended into the treatment area, and then the radio frequency sub-electrode is pushed out from the heat insulation guide pin through the push rod, and the radio frequency sub-electrode has the elastic deformation capability, and after the radio frequency sub-electrode is extended out, the radio frequency sub-electrode is opened under the action of the self deformation force to form a sphere. The current treatment region information also includes the distance between two farthest boundary points of the treatment region, the farthest distance is selected to inactivate the cancerous cells as much as possible, and the distance database stores the mapping relationship between the distance between the two farthest boundary points in the current treatment region range and the expansion range of the radio frequency sub-electrode, which can be obtained through experiments by experimenters, and is not described herein any further.

Step 102: and performing matching analysis according to the propelling distance and the expansion range information stored in the preset distance conversion database to determine the propelling distance corresponding to the expansion range information, and defining the propelling distance corresponding to the expansion range information as propelling distance information.

The advancing distance information is the advancing distance of the push rod. The distance conversion database stores the mapping relation between the propelling distance of the push rod and the expansion range of the radio frequency sub-electrode, and the propelling of the push rod can be operated manually or through an electric pole and the like so as to be accurate and automatic.

Step 103: and extending the radio frequency central electrode into the treatment area and advancing according to the advancing distance information to expand the radio frequency sub-electrodes.

As shown in figure 2, after the RF central electrode reaches the treatment region, the pushing rod is pushed to extend the RF sub-electrode from the thermally insulated guide pin, so as to expand the RF sub-electrode, which is used to increase the treatment range.

Step 104: and acquiring electrode temperature information of a front terminal electrode of the radio frequency central electrode and cell temperature information corresponding to the current treatment area information.

The front terminal of the radio frequency central electrode is the farthest end of the radio frequency central electrode extending out of the heat insulation guide pin. The electrode temperature information is the temperature of the front terminal of the radio frequency center electrode in the working process. The cell temperature information is the temperature of the cell surface in the current treatment area before treatment, typically the temperature of the corresponding organ of the human body. The acquisition mode is any instrument capable of sensing the temperature change and outputting a temperature value, such as a temperature sensor. The front terminal of the radio frequency central electrode is provided with a temperature sensor, when the front terminal of the radio frequency central electrode reaches a working area and before the radio frequency central electrode works, cell temperature information is acquired, and after the radio frequency central electrode works, the electrode temperature information is acquired.

Step 105: and calculating temperature difference information according to the electrode temperature information and the cell temperature information.

The temperature difference information is the difference between the electrode temperature information and the cell temperature information, and is calculated by subtracting the electrode temperature information and the cell temperature information from each other, and the calculation is performed for the purpose of determining the rate at which the electrode temperature information rises.

Step 106: and performing matching analysis according to the current power and the temperature difference information stored in the preset temperature control database to determine the current power corresponding to the temperature difference information, and defining the current power corresponding to the temperature difference information as the current power information.

And the current power information is the current power corresponding to the temperature difference information. The temperature control database stores the mapping relation between the temperature difference and the current power, and in the embodiment of the application, the larger the temperature difference is, the smaller the current power is, so that the temperature rise process can be controlled, and the carbonization phenomenon is not easy to occur in the temperature rise process.

Step 107: the radio frequency transmitter outputs power to the radio frequency central electrode according to the current power information and raises the temperature of the radio frequency central electrode and the radio frequency sub-electrodes so as to ablate the cancer cells in the treatment area.

When the radio frequency central electrode is inserted, the radio frequency transmitter generates current power corresponding to the current power information, so that the temperature of the radio frequency central electrode and the radio frequency sub-electrode is increased to start the treatment of the canceration area.

Referring to fig. 3, the temperature increasing method of the rf center electrode and the rf sub-electrode includes:

step 200: and acquiring the highest treatment temperature information.

The highest treatment temperature information is preset proper working temperature, namely the temperature input by a worker according to actual conditions before the radio frequency ablation equipment works. The input mode is shown in fig. 2, namely a button on the radio frequency generator is used for selecting the temperature gear. In the present embodiment, the maximum treatment temperature information may be four levels of 80 ℃, 85 ℃, 90 ℃ and 95 ℃.

Step 201: and calculating the temperature difference between the electrode temperature information and the temperature value corresponding to the highest treatment temperature information, and defining the temperature difference as temperature control difference information.

The temperature control difference information is the difference between the electrode temperature information and the maximum treatment temperature information, and the purpose of calculation is to judge whether the electrode temperature information exceeds the maximum treatment temperature.

Step 202: and judging whether the temperature difference corresponding to the temperature control difference information is a positive value.

Step 2021: and if so, judging whether the temperature difference value corresponding to the temperature control difference value information falls into a preset temperature difference range.

The temperature difference range refers to a maximum value allowed to appear by the temperature control difference information, namely a maximum value that the temperature can rise after the temperature difference corresponding to the temperature control difference information is a positive value. When the temperature difference value corresponding to the temperature control difference value information is a positive value, it indicates that the electrode temperature information has exceeded the maximum treatment temperature, and there is a case where other cells are ablated and there is a possibility that the ablated cancerous cells are easily charred, so that subsequent determination and detection are required. In this embodiment, the ablation treatment temperature is 120 ℃ maximum.

Step 2022: and if the current power is not a positive value, outputting according to the current power information.

And when the temperature difference corresponding to the temperature control difference information is not a positive value, which indicates that the maximum treatment temperature is not reached, the temperature is required to be increased.

Step 2031: and if the current power falls into the preset temperature difference range, outputting according to the current power information.

And when the difference value corresponding to the temperature control difference value information falls into the preset temperature difference range, which indicates that the temperature control does not exceed the maximum temperature, ablation can be performed, and the radio frequency central electrode and the radio frequency sub-electrode output ablation according to the current power information.

Step 2032: if the temperature difference does not fall into the preset temperature difference range, the display sends out preset auditory prompting information and state display information, and the radio frequency transmitter automatically cuts off the output.

When the temperature difference value corresponding to the temperature control difference value information does not fall within the preset temperature difference range, the temperature of the ablation treatment exceeds the limit value, the cells are easy to carbonize when the power output is continued, and the output is cut off immediately.

Referring to fig. 4, the temperature control method includes:

step 300: saline temperature information of physiological saline is acquired.

The brine temperature information is temperature information of brine at normal temperature, the temperature is measured at the position of brine input in an acquisition mode, and a temperature measuring device can be any temperature acquiring device, such as: a thermometer, etc.

Step 301: calculations are made based on the brine temperature information and the electrode temperature information to determine brine temperature difference information.

The brine temperature difference information is a difference in temperature between the brine temperature information and the electrode temperature information. The purpose of the calculation is to determine the difference between the saline and the elevated temperature of the electrodes to determine the degree of reduction in the current temperature after saline input.

Step 302: and performing matching analysis according to the flow rate of the physiological saline stored in the preset cooling database and the saline temperature difference information to determine the flow rate of the physiological saline corresponding to the saline temperature difference information, and defining the flow rate of the physiological saline corresponding to the saline temperature difference information as flow rate information.

The flow rate information is information of the flow rate of the physiological saline water. The cooling database stores the mapping relation between the flow rate of the physiological saline and the saline temperature difference information, namely different saline works according to the optimum flow rate matched in the cooling database, and the electrode temperature can be quickly reduced to the highest treatment temperature.

Step 303: and judging whether the flow velocity information is larger than the preset safe flow velocity information.

The purpose of judgment is to prevent the physiological saline from fast cooling other areas and causing discomfort to human body.

Step 3031: and if the flow rate information is larger than the preset safe flow rate information, inputting the physiological saline from a guide pipe in the radio frequency transmitter according to the safe flow rate information.

If the flow rate information is greater than the preset safe flow rate information, which indicates that the flow rate is too fast, in the radio frequency transmitter of fig. 2, the flow rate of the physiological saline needs to be injected from the saline injection port according to the flow rate corresponding to the safe flow rate information.

Step 3032: and if the flow rate information is less than the preset safe flow rate information, inputting the physiological saline from a guide pipe in the radio frequency transmitter according to the flow rate information.

If the flow rate information is larger than the preset safe flow rate information, the flow rate is normal, other negative effects on the human body are not caused, and the input can be carried out. The flow rate of the physiological saline is injected from the saline injection port at a flow rate corresponding to the flow rate information.

Step 304: and acquiring the input time information of the physiological saline.

The input time information is the injection duration information after the start of the injection of the physiological saline, the acquisition mode is any counter, and it should be noted that after the injection of the physiological saline is finished, the numbers on the counters all need to return to 0.

Step 305: a calculation is made based on the flow rate information and the input time information to determine an input amount of the physiological saline, which is defined as flow rate information.

The flow information is the injection amount of the physiological saline. The formula of the calculation is as follows: and the flow information L = VT, wherein V is flow speed information, and T is input time information.

Step 306: and comparing the physiological saline input quantity corresponding to the flow information with the preset safe input quantity.

The safe input amount is the total amount of normal physiological saline injected into a human body, and when the safe input amount exceeds the value, the human body is easy to feel uncomfortable, and the specific value is set by a person skilled in the art through long-term experience. The purpose of the comparison is to prevent the human body from influencing the health due to the injection of excessive physiological saline.

Step 3061: and if the physiological saline input amount corresponding to the flow information is equal to the preset safe input amount, the physiological saline is not input.

And if the input amount of the physiological saline corresponding to the flow information is equal to the preset safe input amount, the fact that the injection reaches the limit is indicated, the physiological saline cannot be injected again, and then the input is stopped. It should be noted that when the limit is reached, the saline is not injected any more, so there is little or no case where the input amount of the saline corresponding to the flow information is greater than the preset safe input amount.

Step 3062: and if the physiological saline input amount corresponding to the flow information is smaller than the preset safe input amount, inputting the physiological saline from a guide pipe in the radio frequency transmitter.

If the input amount of the physiological saline corresponding to the flow information is smaller than the preset safe input amount, the physiological saline can still be received by the human body and the health is not affected, and then the physiological saline can be continuously injected.

Referring to fig. 5, a method of controlling radio frequency ablation includes:

step 400: and acquiring current time length information of the power output by the radio frequency transmitter to the radio frequency central electrode.

The current time length information is the working time length of the radio frequency central electrode, that is, the radio frequency central electrode starts to time when working, and the timing mode can be any timing device, such as a counter.

Step 401: and performing matching analysis according to the corresponding treatment duration and the current treatment area information in the preset treatment duration database to determine and obtain the treatment time information of the output power of the radio frequency transmitter to the radio frequency central electrode.

The treatment time information is the optimum treatment duration corresponding to different treatment region sizes, the mapping relation between the area range of the current treatment region information and the treatment duration is stored in the treatment duration database, and the database is obtained by workers in the field through long-term tests. When the area of the current treatment region information is input, the area is matched with the range in the database, and the range is mapped to the treatment duration after the range is determined.

Step 402: and comparing the current time length information with the treatment time information.

Step 4021: and if the time length corresponding to the current time length information is equal to the time length corresponding to the treatment time information, the radio frequency transmitter automatically cuts off the output.

If the duration corresponding to the current duration information is equal to the duration corresponding to the treatment time information, the working time of the radio-frequency central electrode reaches the optimal treatment duration, and the cells at the position are prevented from charring without continuously working subsequently. It should be noted that, when the optimal treatment duration is reached, the radio frequency transmitter automatically cuts off the output, so that there is no situation that the duration corresponding to the current duration information is longer than the duration corresponding to the treatment duration information.

Step 4022: and if the duration corresponding to the current duration information is less than the duration corresponding to the treatment time information, the radio frequency transmitter continues to work.

If the duration corresponding to the current duration information is less than the duration corresponding to the treatment time information, it indicates that the optimal treatment duration has not been reached, and the treatment ablation needs to be continued.

Referring to fig. 6, a method of extending a radio frequency center electrode into a treatment area includes:

step 500: and calculating the current treatment center information according to the current treatment area information.

The current treatment center information is the center position corresponding to the current treatment area, and in the embodiment of the application, the center coordinate point is the optimal treatment area because the electrodes of the device are spherical. The calculation may be any one of the ways that the center coordinate point can be determined by the peripheral outline, for example, the central coordinate point can be determined by automatically selecting the peripheral outline by putting the peripheral outline into the CAD drawing.

Step 501: and acquiring the positioning information of the front terminal of the radio frequency central electrode extending into the treatment area.

The front terminal positioning information is the position of the end point of the front terminal of the radio frequency central electrode, and the acquisition mode can be any positioning device, such as a positioning sensor.

Step 502: and judging whether the coordinate point of the front terminal positioning information is superposed with the coordinate point corresponding to the current treatment center information.

The purpose of the judgment is to determine whether the front terminal reaches the optimum working position.

Step 5021: if the coordinate point of the front terminal positioning information is coincident with the coordinate point corresponding to the current treatment center information, the radio frequency transmitter outputs power to the radio frequency central electrode according to the current power information and raises the temperature of the radio frequency central electrode and the radio frequency sub-electrode so as to ablate the cancerous cells in the treatment area.

If the coordinate point of the front terminal positioning information is overlapped with the coordinate point corresponding to the current treatment center information, the radio frequency central electrode and the radio frequency sub-electrode reach the optimal working position to work, and the radio frequency transmitter outputs power to the radio frequency central electrode according to the current power information and raises the temperature of the radio frequency central electrode and the radio frequency sub-electrode so as to ablate the cancerous cells in the treatment area.

Step 5022: and if the coordinate point of the front terminal positioning information is not coincident with the coordinate point corresponding to the current treatment center information, acquiring front terminal temperature information and normal temperature information corresponding to the front terminal positioning information.

If the coordinate point of the front terminal positioning information is not coincident with the coordinate point corresponding to the current treatment center information, it indicates that the front terminal is not at the working position, and may not reach the working position, or may shift during the working process, and the electrode falls off.

Step 503: and comparing the temperature value corresponding to the temperature information of the front terminal with the normal temperature information.

The purpose of the comparison is to determine whether the front terminal is in operation.

Step 5031: if the temperature value corresponding to the front terminal temperature information is equal to the normal temperature information, the front terminal positioning information is adjusted to be coincident with the coordinate point corresponding to the current treatment center information, and the radio frequency transmitter outputs power to the radio frequency central electrode according to the current power information and raises the temperature of the radio frequency central electrode and the radio frequency sub-electrode so as to ablate the cancerous cells in the treatment area.

If the temperature value corresponding to the temperature information of the front terminal is equal to the normal temperature information, it indicates that the front terminal only starts to extend into the treatment area and does not start to work, and the front terminal needs to move to the coordinate point corresponding to the current treatment center information to work.

Step 5032: if the temperature value corresponding to the temperature information of the front terminal is larger than the temperature information of the normal temperature, the display sends preset auditory prompting information and state display information, and the radio frequency transmitter automatically cuts off the output.

If the temperature value corresponding to the temperature information of the front terminal is larger than the normal temperature information, the front terminal is deviated in the working process, the electrode falls off, other healthy positions can be treated and ablated, the health of a human body is affected, and the front terminal needs to be cut off.

Referring to fig. 7, the method of determining the coordinate point of the front terminal positioning information includes:

step 600: current thermally-induced temperature information is acquired.

The current thermally-induced temperature information is the temperature map over the entire treatment area. The acquisition mode is that the infrared sensor acquires, namely different temperatures show different colors.

Step 601: and marking coordinate points with the same current thermal induction temperature information on an electronic map, connecting lines to determine thermal induction temperature rings with the same temperature, and defining the thermal induction temperature rings as the same temperature ring information.

The same temperature circle information is the information of the thermal induction temperature circle of the same temperature. Due to the limitations of the device, different temperatures appear in the form of different concentric circles.

Step 602: and calculating the center of a thermal induction temperature ring at the same temperature according to the same temperature ring information, and defining the center of a circle as a coordinate point of the front terminal positioning information.

The calculation method may be any method that can determine the center coordinate point through the peripheral contour map, for example, the temperature rings corresponding to the same temperature ring information are placed in the CAD map, and the center coordinate point can be determined by automatically selecting the peripheral contour line.

Referring to fig. 8, the method of determining the coordinate point of the front terminal positioning information includes:

step 700: current impedance information on the radio frequency center electrode is acquired.

The current impedance information is the impedance which is the obstruction effect on the radio frequency central electrode to the current in the circuit, and can be obtained through the current change. In the embodiment of the application, the impedance of the radio frequency central electrode before working is a certain value, and the impedance value can change along with the rise of temperature and the loss of moisture in the working process, so that the impedance value can be obtained through the magnitude of the feedback current.

Step 701: and judging whether the current impedance information is a preset initial value or not.

The initial value is the impedance of the RF central electrode in its initial state before no temperature change.

Step 7011: if the current impedance information is not the preset initial value, judging whether the time length corresponding to the current time length information is less than the preset no-treatment-effect time length information.

If the current impedance information is not an initial value, it indicates that the current environment is changing and water is losing, and it indicates that the radio frequency central electrode has entered the working environment and starts working, and it needs to judge whether the treatment is completed.

Step 7012: if the current impedance information is the preset initial value, the radio frequency central electrode is kept unchanged.

If the current impedance information is the preset initial value, it indicates that the work is not started yet, and no change is needed.

Step 7021: if the time length corresponding to the current time length information is longer than the preset time length information without treatment effect, the radio frequency sub-electrode retracts into the guide pin and the radio frequency central electrode normally withdraws.

The duration information without treatment effect is a preset duration of time that the duration is not long enough to have no treatment effect although the radio frequency central electrode is working. If the time length corresponding to the current time length information is longer than the preset time length information without treatment effect, the radio frequency central electrode is treated, and due to heat conduction, the temperature of the surface of the needle rod can reach the temperature for preventing cell inactivation and blood coagulation, so that electrocoagulation is not needed. The high-frequency electrocoagulation treatment technology is characterized in that under ultrasonic positioning, the most advanced high-frequency electrocoagulation treatment instrument and catheter needle are adopted to directly act on elastic fibers and collagen fibers in tumor cell membranes and tissues around blood vessels, high heat is generated in tumor bodies, the blood vessel walls are emulsified, solidified and contracted, the tumor bodies are gradually reduced, and the deformed blood vessels lose the capacity of re-expansion.

Step 7022: if the time length corresponding to the current time length information is less than the preset time length information without treatment effect, the radio frequency generator sends the preset needle channel electrocoagulation information to the radio frequency central electrode to carry out electrocoagulation on the cells.

If the time length corresponding to the current time length information is less than the preset time length information without treatment effect, the heat conduction is not enough to coagulate the blood, and the electrocoagulation is needed.

Step 703: and judging whether the temperature corresponding to the electrode temperature information is consistent with the highest treatment temperature information.

The purpose of the determination is to determine whether a temperature at which electrocoagulation is possible has been achieved.

Step 7031: if the temperature corresponding to the electrode temperature information is consistent with the highest treatment temperature information, the radio frequency sub-electrode retracts into the guide pin and the radio frequency central electrode normally exits.

If the temperature corresponding to the electrode temperature information is consistent with the highest treatment temperature information, the temperature reaches the preset treatment temperature, and the blood can be coagulated by heat conduction to the periphery without electrocoagulation.

Step 7032: if the temperature corresponding to the electrode temperature information is not consistent with the highest treatment temperature information, the radio frequency generator sends preset needle channel electrocoagulation information to the radio frequency central electrode to electrocoagulation the cells.

If the temperature corresponding to the electrode temperature information is not consistent with the maximum treatment temperature information, the treatment temperature is not reached, blood cannot be coagulated, and electrocoagulation is needed.

Based on the same inventive concept, an embodiment of the present invention provides a radio frequency ablation system, including:

referring to fig. 9, a radio frequency ablation system comprising:

an information acquisition module 801, configured to acquire information of a current treatment region;

the processing module 802 is connected with the information acquisition module 801 and used for storing and processing information;

the determining module 803 is connected to the processing module 802, and configured to determine whether the temperature difference corresponding to the temperature difference information is a positive value;

the temperature control module 804 is connected with the processing module 802 and is used for controlling the temperature of the radio frequency central electrode and the radio frequency sub-electrode;

a duration obtaining module 805 connected to the processing module 802, configured to obtain current duration information of the power output from the radio frequency transmitter to the radio frequency center electrode;

a saline control module 806 connected to the processing module 802 for controlling the flow rate information and the input time information of the saline injection;

the false touch prevention module 807 is connected with the processing module 802 and is used for cutting off before the radio frequency central electrode reaches a specified position and when the radio frequency central electrode falls off;

a front terminal positioning module 808 connected to the processing module 802 for positioning the position of the front terminal;

an electrocoagulation module 809 connected to the treatment module 802 for performing electrocoagulation on the cells;

the processing module 802 performs matching analysis according to the expansion range stored in the preset distance database and the current treatment region information to determine the expansion range of the radio frequency sub-electrode required by the current treatment region, and defines the expansion range as expansion range information;

the processing module 802 performs matching analysis according to the propulsion distance and the extension range information stored in the preset distance conversion database to determine the propulsion distance corresponding to the extension range information, and defines the propulsion distance as propulsion distance information;

the processing module 802 extends the radio frequency central electrode into the treatment area and advances according to the advancement distance information to expand the radio frequency sub-electrodes;

the information acquisition module 801 acquires electrode temperature information of a front terminal electrode of the radio frequency central electrode and cell temperature information corresponding to current treatment area information;

the processing module 802 calculates temperature difference information according to the electrode temperature information and the cell temperature information;

the processing module 802 performs matching analysis according to the current power and the temperature difference information stored in the preset temperature control database to determine the current power corresponding to the temperature difference information, and defines the current power as the current power information;

the processing module 802 controls the rf transmitter to output power to the rf central electrode according to the current power information and increases the temperature of the rf central electrode and the rf sub-electrodes to ablate the cancerous cells in the treatment region.

Embodiments of the present invention provide a computer readable storage medium storing a computer program that can be loaded by a processor and executed to perform a radio frequency ablation method.

Computer storage media include, for example: various media capable of storing program codes, such as a usb disk, a removable hard disk, a Read-Only Memory (ROM), a Random Access Memory (RAM), a magnetic disk, or an optical disk.

Based on the same inventive concept, the embodiment of the invention provides an intelligent terminal, which comprises a memory and a processor, wherein the memory is stored with a computer program which can be loaded by the processor and can execute the radio frequency ablation method.

It will be clear to those skilled in the art that, for convenience and simplicity of description, the foregoing division of the functional modules is merely used as an example, and in practical applications, the above function distribution may be performed by different functional modules according to needs, that is, the internal structure of the device is divided into different functional modules to perform all or part of the above described functions. For the specific working processes of the system, the apparatus and the unit described above, reference may be made to the corresponding processes in the foregoing method embodiments, and details are not described here again.

The foregoing is a preferred embodiment of the present application and is not intended to limit the scope of the present application in any way, and any features disclosed in this specification (including the abstract and drawings) may be replaced by alternative features serving equivalent or similar purposes, unless expressly stated otherwise. That is, unless expressly stated otherwise, each feature is only an example of a generic series of equivalent or similar features.

Claims

1. A radio frequency ablation system, comprising:

the electrocoagulation module is connected with the treatment module and is used for performing electrocoagulation operation on the cells;

the processing module performs matching analysis according to the expansion range stored in the preset distance database and the current treatment area information to determine the expansion range of the radio frequency sub-electrode required by the current treatment area, and defines the expansion range of the required radio frequency sub-electrode as expansion range information;

the processing module extends the radio frequency central electrode into the treatment area and advances the radio frequency central electrode according to the advancing distance information to expand the radio frequency sub-electrodes;

the information acquisition module acquires the highest treatment temperature information;

the processing module calculates the temperature difference between the electrode temperature information and the temperature value corresponding to the highest treatment temperature information, and defines the temperature difference as temperature control difference information;

the judging module is connected with the processing module and used for judging whether the temperature difference value corresponding to the temperature control difference value information is a positive value or not;

if the judgment module judges that the temperature difference value is a positive value, the judgment module judges whether the temperature difference value corresponding to the temperature control difference value information falls into a preset temperature difference range;

if the judgment module judges that the temperature difference falls into the preset temperature difference range, the electrocoagulation module outputs the current power information;

if the judgment module judges that the temperature difference does not fall into the preset temperature difference range, the processing module controls the display to send preset auditory prompting information and state display information, and the radio-frequency transmitter automatically cuts off output;

if the judgment module judges that the current power information is not a positive value, the processing module outputs the current power information;

2. A radio frequency ablation system according to claim 1, comprising:

the saline control module is connected with the processing module and used for controlling the flow rate information and the input time information of the physiological saline injection;

the information acquisition module acquires saline temperature information of the physiological saline;

the processing module calculates according to the brine temperature information and the electrode temperature information to determine brine temperature difference information;

the processing module performs matching analysis according to the flow rate of the physiological saline and the saline temperature difference information stored in the preset cooling database to determine the flow rate of the physiological saline corresponding to the saline temperature difference information, and defines the flow rate of the physiological saline as flow rate information;

the judging module judges whether the flow velocity information is larger than preset safe flow velocity information;

if the judgment module judges that the flow rate information is larger than the preset safe flow rate information, the saline control module inputs the physiological saline from a guide pipe in the radio frequency transmitter according to the safe flow rate information;

if the judgment module judges that the flow rate information is less than the preset safe flow rate information, the saline control module inputs the physiological saline from a guide pipe in the radio frequency transmitter according to the flow rate information;

the saline control module acquires input time information of physiological saline;

the processing module calculates according to the flow rate information and the input time information to determine the input amount of the physiological saline, and the input amount is defined as flow information;

the judgment module compares the physiological saline input quantity corresponding to the flow information with the preset safe input quantity;

if the judgment module judges that the input quantity of the physiological saline corresponding to the flow information is equal to the preset safe input quantity, the saline control module controls the physiological saline not to be input;

and if the judgment module judges that the input quantity of the physiological saline corresponding to the flow information is less than the preset safe input quantity, the saline control module controls the physiological saline to be input from the guide pipe in the radio frequency transmitter.

3. A radio frequency ablation system according to claim 2, comprising:

the time length obtaining module is connected with the processing module and is used for obtaining the current time length information of the power output to the radio frequency central electrode by the radio frequency transmitter;

the processing module performs matching analysis according to the corresponding treatment duration and the current treatment area information in the preset treatment duration database to determine and obtain treatment time information of the output power of the radio frequency transmitter to the radio frequency central electrode;

the judgment module compares the current duration information with the treatment time information;

if the judging module judges that the time length corresponding to the current time length information is equal to the time length corresponding to the treatment time information, the electrocoagulation module controls the radio frequency transmitter to automatically cut off the output;

if the judgment module judges that the time length corresponding to the current time length information is less than the time length corresponding to the treatment time information, the electrocoagulation module controls the radio frequency transmitter to continue working.

4. A radio frequency ablation system according to claim 1, comprising:

the processing module calculates the current treatment center information according to the current treatment area information;

the front terminal positioning module is connected with the processing module and is used for acquiring front terminal positioning information of the radio frequency central electrode extending into the treatment area;

the false touch prevention module is connected with the processing module and is used for cutting off before the radio frequency central electrode does not reach the designated position and when the radio frequency central electrode falls off;

the judging module judges whether the coordinate point of the front terminal positioning information is superposed with the coordinate point corresponding to the current treatment center information;

if the judgment module judges that the coordinate point of the front terminal positioning information is coincident with the coordinate point corresponding to the current treatment center information, the electrocoagulation module controls the radio frequency transmitter to output power to the radio frequency central electrode according to the current power information and raises the temperature of the radio frequency central electrode and the radio frequency sub-electrode so as to ablate the cancerous cells in the treatment area;

if the judging module judges that the coordinate point of the front terminal positioning information is not coincident with the coordinate point corresponding to the current treatment center information, the information acquiring module acquires the front terminal temperature information and the normal temperature information corresponding to the front terminal positioning information;

the judging module compares the temperature value corresponding to the temperature information of the front terminal with the normal temperature information;

if the judging module judges that the temperature value corresponding to the temperature information of the front terminal is equal to the normal temperature information, the processing module adjusts the positioning information of the front terminal to enable the positioning information of the front terminal to be superposed with a coordinate point corresponding to the current treatment center information, and the electrocoagulation module controls the radio frequency transmitter to output power to the radio frequency central electrode according to the current power information and raises the temperature of the radio frequency central electrode and the radio frequency sub-electrode so as to ablate the cancerous cells in the treatment area;

if the judging module judges that the temperature value corresponding to the temperature information of the front terminal is larger than the normal temperature information, the processing module controls the display to send preset auditory prompting information and state display information, and the electrocoagulation module controls the radio frequency transmitter to automatically cut off the output.

5. A radio frequency ablation system according to claim 4, comprising:

the information acquisition module acquires current thermal induction temperature information;

the processing module marks coordinate points with the same current thermal induction temperature information on an electronic map and performs connection to determine thermal induction temperature rings with the same temperature, and the thermal induction temperature rings are defined as the same temperature ring information;

the front terminal positioning module calculates the circle center of the thermal induction temperature ring at the same temperature according to the same temperature ring information, and defines the circle center as a coordinate point of the front terminal positioning information.

6. A radio frequency ablation system according to claim 3, comprising:

the information acquisition module acquires current impedance information on the radio frequency central electrode;

the judging module judges whether the current impedance information is a preset initial value;

if the judging module judges that the current impedance information is not the preset initial value, the judging module judges whether the time length corresponding to the current time length information is less than the preset no-treatment-effect time length information or not;

if the judging module judges that the time length corresponding to the current time length information is greater than the preset treatment effect-free time length information, the radio frequency sub-electrode of the processing module retracts into the guide pin and the radio frequency central electrode normally retracts;

the judging module judges whether the temperature corresponding to the electrode temperature information is consistent with the highest treatment temperature information;

if the judgment module judges that the radio frequency sub-electrodes are consistent, the electrocoagulation module controls the radio frequency sub-electrodes to retract into the guide pins and the radio frequency central electrode to normally withdraw;

if the judgment module judges that the time length corresponding to the current time length information is less than the preset time length information without treatment effect or the temperature corresponding to the electrode temperature information is inconsistent with the highest treatment temperature information, the electrocoagulation module controls the radio frequency generator to send the preset needle channel electrocoagulation information to the radio frequency central electrode so as to electrocoagulation the cells.