CN1138548C - Crustaceous extract health care foods and preparation method thereof - Google Patents

Abstract

The present invention discloses a chitin health food and a preparation method thereof, and the chitin health food is mainly composed of 50 to 80% of 0-acetylated chitin and 20 to 50% of chitin. The chitin health food has the functions of improving immunity, preventing diseases, regulating intestinal tracts, delaying aging, etc., and can be eaten by people with poor immunological function, people who recover after suffering from diseases, people with hyperlipoidemia, people who works under special working conditions and people in a sub-health state.

Description

Crustaceous extract health care foods and preparation method thereof

The present invention relates to a kind of health food and preparation method thereof.

Along with improving constantly of living standard, more and more being subject to people's attention of functional health-care food.Functional health-care food is meant the food of nutritious or a certain physiology adjustment function.Can be divided into for four generations at present.First on behalf of condensed food, and as malted milk one class, second on behalf of natural grass order purification food, as lemon tea etc.; The third generation is an ocean food, as spirulina etc.; The 4th generation also was the end of this century, and the product of the beginning of next century now just " emerges ", and Here it is has 1. reinforced immunological; 2. prevent disease; 3. regulate physiological function etc. and be the functional health-care food truly of feature.Wherein the edibility tunicin has received very big concern.And chitin comes from animal, and is closely similar with plant cellulose on the chemical constitution, just in the molecule in the repetitive hydroxyl of second carbon atom (OH) by acetamido (NHCOCH ₃) replaced, so it is a class tunicin.

Chitin is a kind of natural polymer, extensively is present in the shell of crustaceans such as shrimp, Eriocheir sinensis.Nature middle age biosynthesis amount reaches 100 tons more than, is to be only second to cellulosic second largest natural resources.It is biodegradable, dissolves in after removing acetyl group and forms gel in the acidic aqueous solution, and heavy metal ion and other toxin are had stronger adsorption, and human body cell is had stronger affinity, and its edible safety and Saccharum Sinensis Roxb. are approximate.Studies show that in a large number in recent years, it has 1. two-way immunoloregulation function; 2. get rid of the unnecessary bad cholesterol of human body; 3. blood sugar lowering, blood pressure lowering; 4. anticancer shifts; 5. strengthen the liver function; 6. promote gastrointestinal motility; 7. remove interior free yl; 8. treat burn, accelerating wound healing; 9. prevent that medicine such as adhesion is functional.Thereby be called as health necessary " the 6th vital principle " except that sugar, albumen, fat, vitamin and mineral abroad.Owing to above-mentioned comprehensive function and nontoxic is arranged, so, comparatively ideal health care preventive effect is arranged all to physical weakness, rehabilitation after being ill, senile disease and environmental inadequacies etc.Therefore, in recent years, be that the health food of main component constantly goes on the market with the chitin.For example Japanese " rescuing how kind " and domestic " happiness to be pacified " etc.But THE MOLECULAR WEIGHT OF CHITIN is up to 1,000,000, and its functional and its molecular weight, deacetylation etc. are closely related.It is specific functional to have only the chitin of appropriate molecular weight just to have.The pharmacological results shows simultaneously, introduces some group in chitin molecule, can further strengthen its immunologic function, and harmful heavy metal ion has stronger eliminating effect.Therefore, what make a general survey of present listing is the health food of main composition with chitin, owing to its structure-effect relationship is not furtherd investigate, so the functional of chitin is not utilized effectively.

The objective of the invention is to overcome the deficiencies in the prior art, and a kind of functional health-care food with definite functional factor and preparation method thereof is provided.

The present invention realizes by following measure:

The present invention mainly forms (weight percentage) by 50-80% O-acetylated crustacyanin and 20-50% chitin.

The present invention can also add other composition and carry out compositely, and in the hope of better effect, the present invention can also contain 0.5-2.5% vitamin C and 1-5% trace element (weight percentage).

Preparation method of the present invention may further comprise the steps successively:

(1) chitin is soaked with 5% hydrogen peroxide;

(2) chitin is suspended in the mixed liquor of ethanol and acetic acid, and then adds acetic anhydride, normal-temperature reaction 1-4 hour, from reactant mixture, collect the O-acetylated crustacyanin;

(3) carry out mechanical mixture in the ratio of O-acidylate chitin 50-80% and chitin 20-50%.

Chitin can activate by system, promotes its phagocytic activity, strengthens its angtigen presentation ability, strengthens its cooperative effect in other immunne response, thereby realizes that body realizes immunoregulatory to the adjusting of T cell, NK cell and B cell to body.But dissolution of chitin is poor, crystallinity is strong, is unfavorable for being absorbed by the body.And after in its molecule, introducing other group, can give that it is functional more.The chitin health product of the present invention and chitin and U.S.'s listing are cooked the control animal experiment, and its result is as follows: listing health care 0.097 ± 0.024 61.33 ± 7.17 1.70 ± 0.47 product Chitosan@ the present invention 0.149 ± 0.119 72.58 ± 7.17 1.94 ± 0.34 of sample serum hemolysin content (%) lymhocyte transformation rate (%) M Ф phagocytic index chitin 0.092 ± 0.083 65.21 ± 6.43 1.69 ± 0.33 U.S.

This shows that the present invention can obviously strengthen mice serum hemolysin content, promote the conversion of mouse lymphocyte, strengthens mouse peritoneal M Ф phagocytic function.This means in chitin molecule and behind the introducing acetyl group, further strengthened immunologic function.

This functional health-care food is applicable to immunologic hypofunction, work under rehabilitation after being ill, the special operation condition condition and health to be in the crowd of sub-health state edible.

The invention has the advantages that: 1,, further strengthened immunologic function by on the repetitive of chitin, introducing group; 2, owing to improved dissolubility behind the derivatization, further having improved availability 3, pharmacological evaluation and voluntary cooperation clinic trial result shows, have the advantages that dosage is little, function is strong, to immunologic hypofunction, rehabilitation after being ill, work under hyperlipidemia and the special operation condition condition and health to be in the crowd of sub-health state comparatively suitable.

After embodiment 1:10 gram chitin soaks 4 hours with 5% hydrogen peroxide, be placed in 80 milliliters of ethanol and the 20 milliliters of acetic acidreaction devices, added 15 ml acetic anhydride normal-temperature reaction 2 hours, collection O-acetylated crustacyanin from reactant mixture.Get 6 gram O-acetylated crustacyanins and 4 gram chitin mix homogeneously crustaceous extract health care foods of the present invention.

Embodiment 2: prescription of the present invention such as table 1 (weight percentage).

Form	Content
					The O-acetylated crustacyanin	52	?63	?75	?79
Chitin	46	?37	?25	?21
					Vitamin C	1
Trace element	1

Claims (3)

1, a kind of crustaceous extract health care foods is characterized in that mainly forming (weight percentage) by 50-80% O-acetylated crustacyanin and 20-50% chitin.

2, health food as claimed in claim 1 is characterized in that containing 0.5-2.5% vitamin C and 1-5% trace element (weight percentage).

3, the preparation method of health food as claimed in claim 1 is characterized in that in turn including the following steps:

(1) chitin is soaked with 5% hydrogen peroxide;

(2) chitin is suspended in the mixed liquor of ethanol and acetic acid, and then adds acetic anhydride, normal-temperature reaction 1-4 hour, from reactant mixture, collect the O-acetylated crustacyanin;

(3) carry out mechanical mixture in the ratio of O-acetylated crustacyanin 50-80% and chitin 20-50%.