CN113853290B - 基本上平底的聚合物小瓶及其注射拉伸吹塑成型制造方法 - Google Patents

基本上平底的聚合物小瓶及其注射拉伸吹塑成型制造方法 Download PDF

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Publication number
CN113853290B
CN113853290B CN201980088705.4A CN201980088705A CN113853290B CN 113853290 B CN113853290 B CN 113853290B CN 201980088705 A CN201980088705 A CN 201980088705A CN 113853290 B CN113853290 B CN 113853290B
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CN
China
Prior art keywords
mold
vial
pecvd
optionally
polymer
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Application number
CN201980088705.4A
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English (en)
Chinese (zh)
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CN113853290A (zh
Inventor
E·萨德泽维奇
K·W·凯利
M·巴塔扎尔
A·布里兰德
T·E·菲斯克
D·亨顿
B·莫瑞尔
A·塔哈
C·威卡尔特
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Sio2 Pharmaceutical Products LLC
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SIO2 Medical Products Inc
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Publication of CN113853290A publication Critical patent/CN113853290A/zh
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Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00Rigid or semi-rigid containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material or by deep-drawing operations performed on sheet material
    • B65D1/02Bottles or similar containers with necks or like restricted apertures, designed for pouring contents
    • B65D1/0223Bottles or similar containers with necks or like restricted apertures, designed for pouring contents characterised by shape
    • B65D1/0261Bottom construction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1412Containers with closing means, e.g. caps
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/0005Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor characterised by the material
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/02Combined blow-moulding and manufacture of the preform or the parison
    • B29C49/06Injection blow-moulding
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/08Biaxial stretching during blow-moulding
    • B29C49/10Biaxial stretching during blow-moulding using mechanical means for prestretching
    • B29C49/12Stretching rods
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00Rigid or semi-rigid containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material or by deep-drawing operations performed on sheet material
    • B65D1/02Bottles or similar containers with necks or like restricted apertures, designed for pouring contents
    • B65D1/0223Bottles or similar containers with necks or like restricted apertures, designed for pouring contents characterised by shape
    • B65D1/0261Bottom construction
    • B65D1/0276Bottom construction having a continuous contact surface, e.g. Champagne-type bottom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61JCONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14Details; Accessories therefor
    • A61J1/1468Containers characterised by specific material properties
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/02Combined blow-moulding and manufacture of the preform or the parison
    • B29C2049/023Combined blow-moulding and manufacture of the preform or the parison using inherent heat of the preform, i.e. 1 step blow moulding
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/42Component parts, details or accessories; Auxiliary operations
    • B29C49/48Moulds
    • B29C2049/4879Moulds characterised by mould configurations
    • B29C2049/4881Moulds characterised by mould configurations having a mandrel or core e.g. two mould halves with a core in-between
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/42Component parts, details or accessories; Auxiliary operations
    • B29C49/48Moulds
    • B29C2049/4879Moulds characterised by mould configurations
    • B29C2049/4882Mould cavity geometry
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29CSHAPING OR JOINING OF PLASTICS; SHAPING OF MATERIAL IN A PLASTIC STATE, NOT OTHERWISE PROVIDED FOR; AFTER-TREATMENT OF THE SHAPED PRODUCTS, e.g. REPAIRING
    • B29C49/00Blow-moulding, i.e. blowing a preform or parison to a desired shape within a mould; Apparatus therefor
    • B29C49/42Component parts, details or accessories; Auxiliary operations
    • B29C49/48Moulds
    • B29C2049/4879Moulds characterised by mould configurations
    • B29C2049/4892Mould halves consisting of an independent main and bottom part
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29KINDEXING SCHEME ASSOCIATED WITH SUBCLASSES B29B, B29C OR B29D, RELATING TO MOULDING MATERIALS OR TO MATERIALS FOR MOULDS, REINFORCEMENTS, FILLERS OR PREFORMED PARTS, e.g. INSERTS
    • B29K2023/00Use of polyalkenes or derivatives thereof as moulding material
    • B29K2023/38Polymers of cycloalkenes, e.g. norbornene or cyclopentene
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29LINDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00Other particular articles
    • B29L2031/712Containers; Packaging elements or accessories, Packages
    • B29L2031/7158Bottles
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B29WORKING OF PLASTICS; WORKING OF SUBSTANCES IN A PLASTIC STATE IN GENERAL
    • B29LINDEXING SCHEME ASSOCIATED WITH SUBCLASS B29C, RELATING TO PARTICULAR ARTICLES
    • B29L2031/00Other particular articles
    • B29L2031/712Containers; Packaging elements or accessories, Packages
    • B29L2031/7158Bottles
    • B29L2031/716Bottles of the wide mouth type, i.e. the diameters of the bottle opening and its body are substantially identical
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B65CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65DCONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00Rigid or semi-rigid containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material or by deep-drawing operations performed on sheet material
    • B65D1/09Ampoules

Landscapes

  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Manufacturing & Machinery (AREA)
  • Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Ceramic Engineering (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Containers Having Bodies Formed In One Piece (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Blow-Moulding Or Thermoforming Of Plastics Or The Like (AREA)
CN201980088705.4A 2018-11-13 2019-11-13 基本上平底的聚合物小瓶及其注射拉伸吹塑成型制造方法 Active CN113853290B (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201862760542P 2018-11-13 2018-11-13
US62/760,542 2018-11-13
PCT/US2019/061293 WO2020102434A2 (en) 2018-11-13 2019-11-13 Polymer vials with substantially flat bottoms and injection stretch blow molding methods for making the same

Publications (2)

Publication Number Publication Date
CN113853290A CN113853290A (zh) 2021-12-28
CN113853290B true CN113853290B (zh) 2024-07-12

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CN201980088705.4A Active CN113853290B (zh) 2018-11-13 2019-11-13 基本上平底的聚合物小瓶及其注射拉伸吹塑成型制造方法

Country Status (6)

Country Link
US (2) US12478553B2 (enExample)
EP (1) EP3880431B1 (enExample)
JP (1) JP7455828B2 (enExample)
CN (1) CN113853290B (enExample)
CA (1) CA3119648A1 (enExample)
WO (1) WO2020102434A2 (enExample)

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EP4188996A1 (en) * 2020-07-28 2023-06-07 SiO2 Medical Products, Inc. Method and package for reducing the degradation of a drug and/or excipient, e.g. polysorbate stabilizer, in a pharmaceutical product
US20240066146A1 (en) * 2020-12-18 2024-02-29 Sangamo Therapeutics, Inc. Improved pharmaceutical compositions containing adeno-associated viral vector
JP2024513061A (ja) * 2021-03-31 2024-03-21 エスアイオーツー・メディカル・プロダクツ・インコーポレイテッド 原子層堆積コーティングされた医薬品パッケージ、並びに例えば、凍結乾燥/コールドチェーン薬物/ワクチン用の改善されたシリンジ及びバイアル
WO2022232349A1 (en) * 2021-04-28 2022-11-03 Fina Technology, Inc. Low friction isbm bottles
EP4337281A1 (en) 2021-05-11 2024-03-20 SiO2 Medical Products, Inc. Drug primary package having integrated rfid tag
CN116730612B (zh) * 2023-07-13 2025-08-01 中国建筑材料科学研究总院有限公司 一种光学玻璃及其制备方法和应用
US20250042595A1 (en) * 2023-08-04 2025-02-06 Canon Kabushiki Kaisha Liquid storage bottle
WO2025101449A1 (en) * 2023-11-09 2025-05-15 Corning Incorporated Designed bottom and flange ring-off breakage of strengthened glass containers via geometrical features

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Also Published As

Publication number Publication date
JP2022507207A (ja) 2022-01-18
CA3119648A1 (en) 2020-05-22
WO2020102434A3 (en) 2020-07-23
EP3880431B1 (en) 2024-08-14
EP3880431A2 (en) 2021-09-22
US12478553B2 (en) 2025-11-25
WO2020102434A2 (en) 2020-05-22
CN113853290A (zh) 2021-12-28
US20260076872A1 (en) 2026-03-19
JP7455828B2 (ja) 2024-03-26
US20220008292A1 (en) 2022-01-13

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Address after: Alabama, USA

Patentee after: SIO2 Pharmaceutical Products Limited Liability Company

Country or region after: U.S.A.

Address before: Alabama, USA

Patentee before: SIO2 MEDICAL PRODUCTS, Inc.

Country or region before: U.S.A.