CN1138480A - "Weixuekang", a medicine for blood health - Google Patents
"Weixuekang", a medicine for blood health Download PDFInfo
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Abstract
A Chinese patent medicine for preventing leukocytopenia and by-effect generation after chemicotherapy of cancer patient, nourishing spleen, kidney, blood and Ying, regulating organism balance and increasing immunity is prepared with prescription A and B, A for promoting blood circulation and B for nourishing blood.
Description
The present invention relates to a kind of Chinese herbal and crude drugs preparations infantile health-care capsule that peripheral blood leucocyte reduces for the treatment of, it can the interfere with chemotherapy medicine falls the generation of white side reaction, for improving chemotherapeutic efficacy, benefits the patient guarantee is provided.
At present, chemotherapy and radiotherapy are two kinds of main means of treatment malignant tumor, these two kinds of Therapeutic Method all can bring the damage of hemopoietic function of bone marrow in various degree, show as the peripheral vein blood leukocytes, platelet count, even hematochrome descends, thereby limited this two kinds of Therapeutic Method raisings on dosage, and the raising of its curative effect has been produced very big influence.In order to prevent and treat the inhibition of the hemopoietic function of bone marrow that chemotherapy and radiation brings, research has in this respect both at home and abroad dropped into a lot of human and material resources and financial resources, also obtained some progress, but the deficiency that exists is more outstanding.In the western modern medicine field, adopt genetic engineering, people have created granulocyte colony-stimulating factor, the macrophage granulocyte colony-stimulating factor, products such as erythropoietin, to prevention and treatmentization, although the bone marrow depression that radiotherapy causes all has certain short term effect, but, exist following problem: (1) drug price is expensive unusually, usually the average daily level of consumption of general treatment (or prophylactic treatment) everyone more than the RMB nearly 1,000 yuan, the medication expense that is used for this respect in each chemotherapy or radiotherapy course of treatment is at least all in the land more than thousand yuan, can reach about 50,000 yuan at most, in conjunction with the present level of consumption of China, all be too far behind to catch up to most of cancer patients; (2) cure the symptoms, not the disease, the above-mentioned various factors mostly are by stimulating the marrow hemopoietic stem cells differentiation, promote the release of " medullary cell storage pool " to reach the rising that improves the peripheral blood cells level, the even effect that lacks " consolidating the training source ".If the human bone marrow is likened to the farmland, so this treatment is like being to use chemical fertilizer merely.So, repeatedly will occur curative effect after the medication and obviously descend, even invalid, give change, radiotherapy normally cause obstacle.For all the foregoing reasons, domestic Chinese medicine scholar begins to be conceived to the bone marrow depression of adopting treatment by Chinese herbsization, radiotherapy to cause.By clinical practice in recent years, find mainly to have following problem: (1) effect onset is too slow.Take Chinese medicine merely and rise in vain, the cycle that effect occurs is oversize, has incured loss through delay normally carrying out of anticancer therapy.This mainly is because how unreasonable the prescription that the Chinese medicine liter is white is at present, nourishes blood although most prescription can both be noticed enriching yin and nourishing kidney, and the effect of invigorating blood circulation is noted inadequately.(2) dispensing is improper opportunity, how just to begin to take after the hemocyte level descends at present, and it and Chinese medicine effect relax, and the slow characteristics of onset are disagreed.(3) dialectical and execute and control thinking and exist fundamental error, for example simple adopt nourish blood, hot bigger medicine such as tonifying YANG, this and bring the rule of this special topic of leukopenia inconsistent because of chemotherapy, radiotherapy.Behind change, the radiotherapy in the treatment, hemocyte descends, and works as in the theory of Chinese medical science system and sets forth one's views with " heresy ", the institute of heresy gathers, and its gas must be empty, adds that cancer is a yin and yang imbalance, mostly be the deficiency of YIN and cause relative yang hyperactivity, thereby cancer patient shows as deficiency-heat more in change, radiotherapy in the treatment, belong to " asthenia ", the category of " deficiency of qi and blood " is studied carefully its pathogenesis, concerns the closest with spleen, kidney, insufficiency of the spleen then transformation failure of spleen, QI and blood does not have the source of vital function; The then marrow deficiency of suffering from a deficiency of the kidney, insufficiency of essence, then blood declines, thereby when with spleen, the weak argument of suffering from a deficiency of the kidney, by spleen invigorating, the kidney invigorating, YIN nourishing, heat clearing and blood circulation promoting, nourishing blood reaches the purpose of QI invigorating and blood producing.
The objective of the invention is to develop the generation that white side reaction falls in a kind of interfere with chemotherapy, be the Chinese herbal and crude drugs preparations infantile health-care capsule that chemotherapy can be carried out smoothly.It is in the kidney invigorating, according to the principle of " vital energy regualting and blood circulation-promoting, Yin-nourishing and body fluid promoting, nourish blood ", is used for clinical practice with Chinese herbal and crude drugs preparations on the spleen invigorating basis.Infantile health-care capsule is to be made of the blood circulation promoting recipe effect the two assembly sides that invigorate blood circulation and nourish blood: spleen invigorating, the kidney invigorating, YIN nourishing, invigorate blood circulation to take into account and nourish blood; The blood-nourishing prescription effect: spleen invigorating, the kidney invigorating, YIN nourishing, heat clearing away, nourish blood to take into account and invigorate blood circulation, two sides play spleen invigorating, YIN nourishing, heat clearing away, the kidney invigorating altogether, invigorate blood circulation, nourish blood, and reach QI invigorating and blood producing, and the purpose that white side reaction takes place falls in interferenceization, radiotherapy.
The present invention is achieved in that the Chinese herbal and crude drugs preparations infantile health-care capsule that is used for the treatment of the peripheral blood leucocyte minimizing, and it is made of the two assembly sides that invigorate blood circulation and nourish blood,
The composition of a, blood circulation promoting recipe is: the white Fructus Amomi Rotundus 10-15g of Radix Codonopsis 10-15g Rhizoma Atractylodis Macrocephalae 10-15g Fructus Corni 10-15g Poria 10-18g Rhizoma Dioscoreae 10-20g Cortex Moutan 10-18g Radix Rehmanniae 10-20g Carapax Trionycis 10-30g Carapax et Plastrum Testudinis 10-30g fructus lycii 10-15g Caulis Spatholobi 10-30g Herba Ecliptae 10-15g Fructus Ligustri Lucidi 10-18g Squama Manis 10-20g Radix agastaches 10-20g Pericarpium Citri Reticulatae 10-12g Radix Glycyrrhizae 10-20g
The composition of b, blood-nourishing prescription is: the white Fructus Amomi Rotundus 10-15g of Radix Angelicae Sinensis 10-20g Radix Paeoniae Alba 10-20g Radix Rehmanniae 10-20g Caulis Spatholobi 10-30g Rhizoma Polygonati 10-18g fructus lycii 10-15g Fructus Ligustri Lucidi 10-18g Herba Ecliptae 10-15g Radix Polygoni Multiflori 10-20g Fructus Corni 10-15g Squama Manis 10-20g Fructus Psoraleae 10-30g Radix Aucklandiae 3-10g even calls 10-20g Herba Taraxaci 30-60g Radix Glycyrrhizae 6-20g together
The present invention realizes like this; The composition of blood circulation promoting recipe is: the white Fructus Amomi Rotundus 10g of Radix Codonopsis 12g Rhizoma Atractylodis Macrocephalae 10g Fructus Corni 12g Poria 12g Rhizoma Dioscoreae 12g Cortex Moutan 10g Radix Rehmanniae 12g Carapax Trionycis 12g Carapax et Plastrum Testudinis 10g fructus lycii 10g Caulis Spatholobi 15g Herba Ecliptae 12g Fructus Ligustri Lucidi 10g Squama Manis 12g Radix agastaches 10g Pericarpium Citri Reticulatae 9g Radix Glycyrrhizae 6g
The present invention realizes like this; The composition of blood-nourishing prescription is: the white Fructus Amomi Rotundus 10g of Radix Angelicae Sinensis 10g Radix Paeoniae Alba 10g Radix Rehmanniae 10g Caulis Spatholobi 15g Rhizoma Polygonati 10g fructus lycii 10g Fructus Ligustri Lucidi 10g Herba Ecliptae 10g Radix Polygoni Multiflori 10g Fructus Corni 10g Squama Manis 10g Fructus Psoraleae 12g Radix Aucklandiae 4g even calls 10g Herba Taraxaci 15g Radix Glycyrrhizae 6g together
Prescription of the present invention is according to being:
Radix Codonopsis, the Rhizoma Atractylodis Macrocephalae, Poria, Radix Glycyrrhizae are decoction of four noble drugs, and main function is an air making-up and spleen enlivening.Radix Codonopsis tonifying the spleen and stomach vigour; Rhizoma Atractylodis Macrocephalae spleen invigorating dehumidifying promotes transporting and transforming function of the spleen and stomach; Poria can help Radix Codonopsis, Rhizoma Atractylodis Macrocephalae spleen reinforcing, again can eliminating dampness by diuresis, looked after spleen dry, dislike wet physiological characteristics; Strengthening the spleen during Radix Glycyrrhizae is transferred is the effect of air making-up and spleen enlivening altogether.Liver, kidney channel are equalled, gone into to Fructus Ligustri Lucidi sweet in the mouth, hardship, property.The energy nourishing the liver and kidney, strong muscles and bones, crow palpus hair color, treating the liver kidney deficiency, dizziness, tinnitus etc.Liver, stomach warp are gone in Herba Ecliptae sweet in the mouth, acid, cold in nature.Can nourish blood by kidney tonifying, cooling blood for hemostasis, crow must hair color.Be used for the treatment of the hepatic and renal YIN deficiency, the caused haematemesis of overabundant liver-fire, spitting of blood, hematuria, have blood in stool, multiple hemorrhage such as metrostaxis.Fructus Ligustri Lucidi, Herba Ecliptae two medicines share, and go into liver, kidney two warps, and Xiang Yuanwei usefulness promotes mutually, invigorating the liver and kidney, and bone and muscle strengthening, clearind deficient heat is treated insomnia, and cooling blood for hemostasis can be controlled hyperactivity of fire caused by deficiency of YIN, absurd row of forcing blood and the various disease of losing blood.The Carapax Trionycis salty in the mouth, property is flat, goes into the liver,spleen,kidney warp.But the moon of nourish liver and kidney, and attracting the floating YANG downward, the treating the liver kidney deficiency, hectic fever night sweat, it is obstructed to control menstruation, hepatosplenomegaly etc.Carapax et Plastrum Testudinis distinguishes the flavor of, sweet, property flat, goes into kidney, the heart, Liver Channel.But nourishing kidney and the floating sun of diving, treating the liver kidney deficiency, hectic fever due to YIN-deficiency consumptive fever, hectic fever night sweat.Carapax Trionycis, Carapax et Plastrum Testudinis two medicines share, the Carapax Trionycis nourishing YIN for suppressing the hyperactive YANG, and replenishing YIN and removing heat, the eliminating stagnation painful abdominal mass that disappears, the Carapax et Plastrum Testudinis nourishing YIN for suppressing the hyperactive YANG, benefit can be good for bone, and common 5 usefulness of two medicines are mutually promoted, and negative and positive are harmonious, and an arteries and veins of superintending and directing develops simultaneously.The Rhizoma Dioscoreae sweet in the mouth, property is flat, and lung is supported in spleen reinforcing, YIN nourishing and the production of body fluid promoting, supplementing the kidney to control the nocturnal overweights tonifying spleen-yin.Radix Aucklandiae bitter in the mouth, warm in nature, go into spleen, stomach, large intestine, gallbladder meridian, fragrant odour, all gas of energy lifting is good at falling lung qi, dispersing liver-energy, and temper.Radix Polygoni Multiflori bitter in the mouth, puckery, slightly warm in nature are gone into liver, kidney channel.Be longer than into kidney, Kidney-Yin to take a tonic or nourishing food to build up one's health, beneficial essence is filled out marrow, cures mainly Liver and kidney two void.The Arillus Longan invigorating the heart and spleen, tranquilizing by nourishing the heart.Squama Manis distinguishes the flavor of after concocting, and cold nature is returned liver, stomach warp, and for oral administration have promoting tissue regeneration by removing blood stasis, the effect of the stimulating milk secretion of stimulating the menstrual flow.Because of but its meridian dredging reaches the disease place, with the promoting the circulation of blood eliminating stagnation, we get the effect of its vital energy regualting and blood circulation-promoting.Play altogether full side: air making-up and spleen enlivening, the effect that nourishing the liver and kidney, hemopoietic are enriched blood.
Good effect of the present invention is:
1, the present invention falls in interferenceization, radiotherapy has its Main Feature of obvious, sure effect to be not only aspect the white side reaction to prevent that the peripheral blood leucocyte that anticancer chemicals and lonizing radiation cause from descending, and can also nurse one's health the equilibrium between yin and yang of malignant tumor patient human body, improve its immunity, can reach the purpose of anticancer therapy.
2, the present invention is mainly used in the auxiliary treatment in malignant tumorization, the radiotherapy in the treatment, and the auxiliary treatment of the various diseases in " asthenia " category, as reaching long-term Chronic consumptions after puerperal, postoperative, the wound.
3, the present invention has cheaply, is suitable for the characteristics of extensive use and taking convenience.
4, the present invention is a Chinese herbal and crude drugs preparations, has embodied the characteristics that a medicine can reach multiple curative effect of taking, and in the anti-malignant tumor treatment, rationally utilizes motherland's medicine and pharmacology that new thinking and method is provided.
Fig. 1 is a process chart of the present invention:
The present invention is described in further detail below in conjunction with accompanying drawing.
The first step, press blood circulation promoting recipe Radix Codonopsis 12g, Rhizoma Atractylodis Macrocephalae 10g, Fructus Corni 12g, Poria 12g, Rhizoma Dioscoreae 12g, Cortex Moutan 10g, Radix Rehmanniae 12g, Carapax Trionycis 12g, Carapax et Plastrum Testudinis 10g, fructus lycii 10g, Caulis Spatholobi 15g, Herba Ecliptae 12g, Fructus Ligustri Lucidi 10g, Squama Manis 12g, white Fructus Amomi Rotundus 10g, Radix agastaches 10g, Pericarpium Citri Reticulatae 9g, Radix Glycyrrhizae 6g, by measuring 1000 doses of doses containing of above 18 kinds of medicines, heavy altogether 196Kg, put into multi-function extractor, add 10 times of amounts of ordinary water (about 1960L), with be steam heated to 50 ℃ the insulation and warm macerating 1h (hour), then with being steam heated to boiling, turn down throttle flow, keep boiling 1h, extracting solution is passed through filter, in the suction receiver; Medicinal residues add 8 times of amounts of ordinary water (about 1568L) according to first decocting time, boil 40 minutes, and extracting solution is passed through filter, in the suction receiver and merge extracted twice liquid.
Second step, total extracting solution is sent in the vaporizer, steam is heated and is concentrated into the phase specific density and is not less than 1.17 and puts cold rnning and go into ethanol and make and contain alcohol amount and reach 65%, leaves standstill 48h, filters decompression filtrate recycling ethanol with filter stick.Being concentrated into the phase specific density is not less than 1.25 and puts cold total extraction extractum that makes.
The 3rd the step, will always extract extractum, add water recently distilled to 1/2 of extractum total amount, stir, add 0.5% active carbon and be heated to 95 ℃, kept 30 minutes, be cooled to room temperature, put and leave standstill 48h in the freezer, the filtration.
The 4th step, filtrate are transferred pH value to 8.0 with 5%NaOH, and the adding saccharin sodium is an amount of, and essence is an amount of, and adding distil water can make the infantile health-care capsule Huoxue preparation of 100000ml to full dose.
The 5th the step, with empty ampoule pure water washed twice, the 2nd time the company water put into disinfection cabinet, be steam heated to 110 ℃, sterilized 30 minutes, get rid of residual water, drying.
The 6th goes on foot, the filtrate and the qualified ampoule of passed examination is put on the filling machine, before each fill, earlier wash filling machine, adjust the fill amount, 20 of examination fills with a small amount of tube with pure water, after qualified, can carry out fill, the ampoule flowing steam heating after the fill, preheating 30 minutes to 110 ℃, sterilized 45 minutes, and put cold.
The 7th step, the ampoule after will sterilize, day is looked lamp inspection, hunts leak loading amount, foreign body, clarity, the bacterium of sampling simultaneously inspection is measured pH value between 5.5-6.5, labels after the passed examination, puts into carton, 10 in every box, every 10ml amounts to 1000 boxes, and the big case of packing into is put into the quality certification.Joint sealing is filled in (seal) case outer name of an article, lot number, date of manufacture and weight.
Can process the preparation that nourishes blood of infantile health-care capsule by blood-nourishing prescription with above preparation technology, its processing technique is:
The first step, press blood-nourishing prescription Radix Angelicae Sinensis 10g, Radix Paeoniae Alba 10g, Radix Rehmanniae 10g, Caulis Spatholobi 15g, Rhizoma Polygonati 10g, fructus lycii 10g, Fructus Ligustri Lucidi 10g, Herba Ecliptae 10g, Radix Polygoni Multiflori 10g, Fructus Corni 10g, Squama Manis 10g, Fructus Psoraleae 12g, Radix Aucklandiae 4g, white Fructus Amomi Rotundus 10g, connect and call 10g together, Herba Taraxaci 15g, Radix Glycyrrhizae 6g is by measuring 1000 doses of doses containing of above 17 kinds of medicines, heavy altogether 172Kg, put into multi-function extractor, add 10 times of amounts of ordinary water (about 1720L), with be steam heated to 50 ℃ the insulation and warm macerating 1h (hour), then with being steam heated to boiling, turn down throttle flow, keep boiling 1h, extracting solution is passed through filter, in the suction receiver; Medicinal residues add 8 times of amounts of ordinary water (about 1376L) according to first decocting time, boil 40 minutes, and extracting solution is passed through filter, in the suction receiver and merge extracted twice liquid.
Second step, total extracting solution is sent in the vaporizer, steam is heated and is concentrated into the phase specific density and is not less than 1.17 and puts cold rnning and go into ethanol and make and contain alcohol amount and reach 65%, leaves standstill 48h, filters decompression filtrate recycling ethanol with filter stick.Being concentrated into the phase specific density is not less than 1.25 and puts cold total extraction extractum that makes.
The 3rd the step, will always extract extractum, add water recently distilled to 1/2 of extractum total amount, stir, add 0.5% active carbon and be heated to 95 ℃, kept 30 minutes, be cooled to room temperature, put and leave standstill 48h in the freezer, the filtration.
The 4th step, filtrate are transferred pH value to 8.0 with 5%NaOH, and it is an amount of to add saccharin sodium, and essence is an amount of, and adding distil water is to full dose, the infantile health-care capsule that can the make 100000ml preparation that nourishes blood.
The 5th the step, with empty ampoule pure water washed twice, the 2nd time the company water put into disinfection cabinet, be steam heated to 110 ℃, sterilized 30 minutes, get rid of residual water, drying.
The 6th goes on foot, the filtrate and the qualified ampoule of passed examination is put on the filling machine, before each fill, earlier wash filling machine, adjust the fill amount, 20 of examination fills with a small amount of tube with pure water, after qualified, can carry out fill, the ampoule flowing steam heating after the fill, preheating 30 minutes to 110 ℃, sterilized 45 minutes, and put cold.
The 7th step, the ampoule after will sterilize, day is looked lamp inspection, hunts leak loading amount, foreign body, clarity, the bacterium of sampling simultaneously inspection is measured pH value between 5.5-6.5, labels after the passed examination, puts into carton, 10 in every box, every 10ml amounts to 1000 boxes, and the big case of packing into is put into the quality certification.Joint sealing is filled in (seal) case outer name of an article, lot number, date of manufacture and weight.
Instructions of taking of the present invention is:
Begin to take the last week blood-activating formula in chemotherapy, divide early, the noon takes for twice 10 of every days (100ml), take continuously after 8 days and use blood-nourishing prescription instead, divide early, the noon takes for twice 10 of every days, take medicine continuously stop two weeks of back to the chemotherapy medication till.
Clinical practice situation of the present invention:
Since in August, 1992, with the water decoction form, in 518 treatment cycle of 207 routine malignant tumor patients, take the infantile health-care capsule interfere with chemotherapy and fall the leukocyte side reaction, 392 treatment cycle of picked at random 168 routine malignant tumor patients are organized in contrast simultaneously.Clothes infantile health-care capsule group patient: male 140 examples, women 67 examples, the range of age 17-72 year, The median age 55.5 years old.Matched group patient man 110 examples, women 58 examples, the range of age 22-68 year, The median age 51 years old.
The group patient that takes medicine began to take the infantile health-care capsule Huoxue preparation in 0-7 days before chemotherapy begins, 10 of every days, logotype was used the preparation that nourishes blood instead after 8 days, took continuously to the chemotherapy medication drug withdrawal till two weeks.The matched group patient takes the sensory trait standard preparation identical with infantile health-care capsule---antipyretic-detoxicant preparation, and instructions of taking is identical with the group of taking medicine.Make discovery from observation, prolong behind bone marrow depression (leukopenia) time of occurrence behind the group of the taking medicine chemotherapy of patients, than the late appearance of matched group 5.76 ± 2.01 days (P＜0.01), leukocyte is lower than lower limits of normal 4.0 * 10
9Individual/ time that L continued shortens than matched group, on average shortens 5.64. ± 2.60 day (P＜0.05), and peripheral blood leucocyte counting minimum clothes infantile health-care capsule medicine group improves (1.52 ± 0.44) * 10 than matched group
9Individual/L (P＜0.01), 275 of leukopenia periodicities do not appear in the group of taking medicine, and matched group is 102, adopts X
gThe check row significance test, the highly significant of the difference tool between two groups is pointed out in P＜0.01.Conclusion prompting is taken medicine and leukopenia occurred after the group chemotherapy and prolong after the time; the persistent period shortens greatly after descending; the numeration of leukocyte minimum increases substantially after the chemotherapy; the chemotherapy that bone marrow is protected increases substantially for the cycle ratio; so side reaction that infantile health-care capsule can disturb or alleviate the reduction numeration of leukocyte that causes because of chemotherapy fully; thereby for chemotherapy guarantee normally is provided, provide condition for further improving chemotherapeutic dosage.
Below further specify curative effect of the present invention with model case.
(1), the king * *, man, 62 years old, physics professor.Admission number 391518 is gone into oncology with the extensive phase companion of right lung small cell lung cancer superior vena cava compressing syndrome on October 5th, 1993 and is done four lesion chemotherapy.Chemotherapy regimen is amycin+different vinblastine+cyclophosphamide+carboplatin, each treatment cycle medication amycin 50mg, different vinblastine 5mg, cyclophosphamide 0.8, carboplatin 0.5, three cycles of shared medicine.First and second treatment cycle end falls white side reaction with the infantile health-care capsule interfere with chemotherapy, and the numeration of leukocyte minimum is respectively 1.1 * 10 after the chemotherapy medication
9Individual/L and 1.9 * 10
9/ L, numeration of leukocyte is lower than 4.0 * 10
9Individual/L institute's persistent period was respectively 8 days and 7 days, respectively through leukocyte composition 8 units of transfusing blood, and blood infusion 150ml * 3 times, hemogram recovers normal level.In the oral infantile health-care capsule light water decoct of period 3 chemotherapy first three day beginning, 400ml every day (potion crude drug) takes at twice, stops back 25 days to the chemotherapy medication, and this same period, the numeration of leukocyte minimum 3.2 * 10
9Individual/L, be lower than normal value lower bound 4.0 * 10
9Individual/L institute's persistent period is 4 days, the end blood transfusion, and it is normal that hemogram recovers voluntarily.
(2), Zheng * *, woman, 30 years old, peasant.Admission number 394628, because of suffer from esophagus in the heart the hypomere scale cancer went into the tumor lesion chemotherapy of being in hospital late period on 13 27th, 1993.Adopt " DDP+5-Fu " scheme for combining chemotherapy.The first treatment cycle medication: cisplatin 60mg * 2,5 fluorouracil, 0.75 * 5, do not take infantile health-care capsule, the numeration of leukocyte minimum is 1.8 * 10 after the medication
9Individual/L, neutrophilic granulocyte counting 0.9 * 10
9Individual/L.Leukocyte is lower than 4.0 * 10
9Individual/L, institute's persistent period reaches 28 days, recovers normal through behind the blood infusion 150ml * 6 times.Second treatment cycle medication DDP60mg * 2.5-Fu1.0 * 5, in changing the oral infantile health-care capsule of first three day beginning, the chemotherapy medication finishes three weeks of back and ends numeration of leukocyte minimum 3.2 * 10 after the medication of this cycle
9Individual/L, neutrophilic granulocyte minimum 2.0 * 10
9Individual/L, numeration of leukocyte is lower than 4.0 * 10
9Individual/L institute's persistent period is 7 days, and the end is through blood transfusion, and it is normal that hemogram recovers voluntarily.
(3), slowly * *, man, 50 years old, peasant.Admission number 394156.Went into tumor lesion chemotherapy because of suffering from esophagus stage casing scale cancer on the 14th in December in 1993.Adopt cisplatin+5 fluorouracil Combination chemotherapy to be aided with HDCF potentiation, treat two cycles, each cycle medication is respectively cisplatin 60mg * 2,5 fluorouracil 0.5 * 5, HDCF 0.1 * 5, period 1 is not fallen white side reaction with the infantile health-care capsule interferenceization, numeration of leukocyte minimum 2.9 * 10 after the chemotherapy
9Individual/L, numeration of leukocyte is lower than lower limits of normal 4.0 * 10
9Individual/L institute's persistent period is 6 days.Control first three sky second round and begin to take infantile health-care capsule, finish three weeks of back to the chemotherapy medication and end, numeration of leukocyte remained in normal range always after the last cycle chemotherapy, and minimum is 5.8 * 10
9Individual/L, neutrophilic granulocyte is very counted minimum 3.1 * 10
9Individual/L.
Claims (3)
1, a kind of Chinese herbal and crude drugs preparations infantile health-care capsule that is used for the treatment of the peripheral blood leucocyte minimizing, it is to be made of the two assembly sides that invigorate blood circulation and nourish blood, and it is characterized in that:
The composition of a, blood circulation promoting recipe is: the white Fructus Amomi Rotundus 10-15g of Radix Codonopsis 10-15g Rhizoma Atractylodis Macrocephalae 10-15g Fructus Corni 10-15g Poria 10-18g Rhizoma Dioscoreae 10-20g Cortex Moutan 10-18g Radix Rehmanniae 10-20g Carapax Trionycis 10-30g Carapax et Plastrum Testudinis 10-30g fructus lycii 10-15g Caulis Spatholobi 10-30g Herba Ecliptae 10-15g Fructus Ligustri Lucidi 10-18g Squama Manis 10-20g Radix agastaches 10-20g Pericarpium Citri Reticulatae 10-12g Radix Glycyrrhizae 10-20g
The composition of b, blood-nourishing prescription is: the white Fructus Amomi Rotundus 10-15g of Radix Angelicae Sinensis 10-20g Radix Paeoniae Alba 10-20g Radix Rehmanniae 10-20g Caulis Spatholobi 10-30g Rhizoma Polygonati 10-18g fructus lycii 10-15g Fructus Ligustri Lucidi 10-18g Herba Ecliptae 10-15g Radix Polygoni Multiflori 10-20g Fructus Corni 10-15g Squama Manis 10-20g Fructus Psoraleae 10-30g Radix Aucklandiae 3-10g even calls 10-20g Herba Taraxaci 30-60g Radix Glycyrrhizae 6-20g together
2, infantile health-care capsule according to claim 1, it is characterized in that the composition of blood circulation promoting recipe is: the white Fructus Amomi Rotundus 10g of Radix Codonopsis 12g Rhizoma Atractylodis Macrocephalae 10g Fructus Corni 12g Poria 12g Rhizoma Dioscoreae 12g Cortex Moutan 10g Radix Rehmanniae 12g Carapax Trionycis 12g Carapax et Plastrum Testudinis 10g fructus lycii 10g Caulis Spatholobi 15g Herba Ecliptae 12g Fructus Ligustri Lucidi 10g Squama Manis 12g Radix agastaches 10g Pericarpium Citri Reticulatae 9g Radix Glycyrrhizae 6g
3, infantile health-care capsule according to claim 1 is characterized in that: the composition of blood-nourishing prescription is: the white Fructus Amomi Rotundus 10g of Radix Angelicae Sinensis 10g Radix Paeoniae Alba 10g Radix Rehmanniae 10g Caulis Spatholobi 15g Rhizoma Polygonati 10g fructus lycii 10g Fructus Ligustri Lucidi 10g Herba Ecliptae 10g Radix Polygoni Multiflori 10g taro meat 10g Squama Manis 10g Fructus Psoraleae 12g Radix Aucklandiae 4g even calls 10g Herba Taraxaci 15g Radix Glycyrrhizae 6g together
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Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102764371A (en) * | 2012-08-09 | 2012-11-07 | 南京中医药大学 | Traditional Chinese medicine compound prescription for relieving radiotherapy side reactions and preparation method and application thereof |
| CN103191304A (en) * | 2013-04-10 | 2013-07-10 | 郑世花 | Traditional Chinese medicine composition for treating blood stasis type aplastic anemia |
| US8897796B2 (en) | 2005-06-30 | 2014-11-25 | Microsoft Corporation | Ordered list channel assignments |
-
1996
- 1996-01-23 CN CN96102614.6A patent/CN1138480A/en active Pending
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US8897796B2 (en) | 2005-06-30 | 2014-11-25 | Microsoft Corporation | Ordered list channel assignments |
| US9055597B2 (en) | 2005-06-30 | 2015-06-09 | Microsoft Technology Licensing, Llc | Systems and methods for making channel assignments to reduce interference and increase capacity of wireless networks |
| US9055598B2 (en) | 2005-06-30 | 2015-06-09 | Microsoft Technology Licensing, Llc | Systems and methods for making channel assignments to reduce interference and increase capacity of wireless networks |
| US9756648B2 (en) | 2005-06-30 | 2017-09-05 | Microsoft Technology Licensing, Llc | Systems and methods for making channel assignments to reduce interference and increase capacity of wireless networks |
| CN102764371A (en) * | 2012-08-09 | 2012-11-07 | 南京中医药大学 | Traditional Chinese medicine compound prescription for relieving radiotherapy side reactions and preparation method and application thereof |
| CN103191304A (en) * | 2013-04-10 | 2013-07-10 | 郑世花 | Traditional Chinese medicine composition for treating blood stasis type aplastic anemia |
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