CN113797259A - Composition for lipolysis - Google Patents
Composition for lipolysis Download PDFInfo
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- CN113797259A CN113797259A CN202010530714.9A CN202010530714A CN113797259A CN 113797259 A CN113797259 A CN 113797259A CN 202010530714 A CN202010530714 A CN 202010530714A CN 113797259 A CN113797259 A CN 113797259A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/22—Anacardiaceae (Sumac family), e.g. smoketree, sumac or poison oak
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/38—Clusiaceae, Hypericaceae or Guttiferae (Hypericum or Mangosteen family), e.g. common St. Johnswort
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/539—Scutellaria (skullcap)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/82—Theaceae (Tea family), e.g. camellia
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/55—Phosphorus compounds
- A61K8/553—Phospholipids, e.g. lecithin
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9783—Angiosperms [Magnoliophyta]
- A61K8/9789—Magnoliopsida [dicotyledons]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/06—Preparations for care of the skin for countering cellulitis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
- A61K2800/5922—At least two compounds being classified in the same subclass of A61K8/18
Abstract
Disclosed is a composition for lipolysis, which contains a lipolysis component and a natural product mixed extract as active ingredients. The natural mixture extract comprises a plum extract, a honeysuckle extract, a scutellaria extract, a melissa extract, a garcinia cambogia extract, a puer tea extract and a mango extract, thereby having an effect of further improving the lipolytic effect of the lipolytic component.
Description
Technical Field
Disclosed is a composition for lipolysis, which contains a lipolysis component and a natural product mixed extract as active ingredients.
Background
Fat is accumulated in the form of triacylglycerol (triacylglycerol) in human body in adipocytes (adipocyte) which are the main fat storage site in the body. High calorie diet patterns and exercise habits with respect to insufficient intake promote proliferation of adipocytes and increase of fat content in adipocytes, leading to obesity and inducing complications such as hypertension. In the food and cosmetic industries, various studies have been made for finding substances that inhibit differentiation of adipocytes or promote decomposition of synthesized fats as means for reducing the amount of fats in addition to improvement of dietary habits and adequate exercise.
On the other hand, cellulite is a phenomenon in which the skin becomes like a rough orange peel depression due to circulatory disturbance caused by accumulation of excessive fat and dirt. The cause of the cellulite is different from simple obesity, but is basically due to increase or hypertrophy of fat cells, and thus the cellulite can be removed by decomposing and discharging fat in the fat cells. In addition, the removal of cellulite can ultimately provide greater assistance in creating slim, slender, smooth stature.
Documents of the prior art
Patent document
Patent document 1: KR 10-2014-0133721A
Disclosure of Invention
Technical problem to be solved
In one aspect, the present invention is directed to a composition for lipolysis comprising a lipolysis component and a natural product mixed extract as active ingredients.
Means for solving the problems
In one aspect, the presently disclosed technology provides the use of a lipolytic ingredient comprising lecithin and sodium deoxycholate and a mixed extract for the manufacture of a composition for lipolytic treatment; and the mixed extract comprises a plum extract, a honeysuckle (Lonicera japonica) extract, a Scutellaria baicalensis (Scutellaria baicalensis) extract, and a Melissa officinalis (Melissa officinalis) extract.
In an exemplary embodiment, the lipolytic ingredient may be used in an amount of 9 to 12% by weight based on the total weight of the lipolytic composition.
In an exemplary embodiment, the mixed extract may be used in an amount of 0.5 to 3 wt% based on the total weight of the composition for lipolysis.
In an exemplary embodiment, the mixed extract may include a plum extract, a honeysuckle extract, a scutellaria root extract and a melissa leaf extract.
In an exemplary embodiment, the mixed extract may include garcinia cambogia extract, puer tea extract and mango extract.
In an exemplary embodiment, the lipolytic composition and mixed extract may be used with propylene carbonate, isoprene glycol, ethanol, PEG-40 hydrogenated castor oil and purified water.
In an exemplary embodiment, the propylene carbonate, the isoprene glycol, the ethanol, the PEG-40 hydrogenated castor oil, and the purified water may be used in an amount of 3 to 7 wt% based on the total weight of the composition for lipolysis, 1 to 5 wt% based on the total weight of the composition for lipolysis, 20 to 24 wt% based on the total weight of the composition for lipolysis, 0.8 to 1.2 wt% based on the total weight of the composition for lipolysis, and 18 to 23 wt% based on the total weight of the composition for lipolysis.
In an exemplary embodiment, the lipolytic composition may be a slimming composition.
In an exemplary embodiment, the lipolytic composition may be a liquid composition.
In an exemplary embodiment, the composition for lipolysis may be a cosmetic composition.
Effects of the invention
On the other hand, the technique disclosed in the present invention has the effect of providing a composition for lipolysis comprising a lipolytic ingredient and a natural product mixed extract as active ingredients.
Detailed Description
The present invention will be described in detail below.
In one aspect, the technology disclosed in the present invention provides a composition for lipolysis comprising a lipolytic component comprising lecithin and sodium deoxycholate and a mixed extract comprising a plum extract, a Lonicera japonica (Lonicera japonica) extract, a Scutellaria baicalensis (Scutellaria baicalensis) extract and a Melissa officinalis (Melissa officinalis) extract as active ingredients.
The mixed extract is not only excellent in storage stability and skin safety, but also provides a remarkably improved lipolytic effect.
In the present specification, an active ingredient means an ingredient that can exhibit a target activity alone or together with a carrier or the like that does not itself exhibit an activity.
In the present specification, the mixed extract may refer to a mixture of extracts extracted from one extraction material, a mixture of extracts extracted by mixing two or more extraction materials, or an extract extracted by mixing and extracting 7 extraction materials.
In the present specification, the extract may be a commercially available extract or an extract produced by a general extract production method known in the art.
In an exemplary embodiment, the extract refers to a processed product including a crude extract in addition to the crude extract, and is in any form, for example, by additional processing such as drying, concentration, fractionation, purification, fermentation, suspension, and the like, and the additional processing may include more than one type of processing. For example, in the case of fractionated extracts, the crude extract is suspended in a specific solvent, mixed with a solvent having a different polarity, and left to stand, and the crude extract is fractionated with a solvent in this order. Further, the extract of the present invention includes fractions obtained by various purification methods additionally performed, such as separation using an ultrafiltration membrane having a certain molecular weight cut-off value, separation by various chromatographs (prepared for separation based on size, charge, hydrophobicity, or affinity), and the like.
In an exemplary embodiment, the method of manufacturing the extract may utilize any means based on a general method such as a hot water extraction method, an immersion extraction method, a steam distillation method, a cold immersion extraction method, a reflux cooling extraction method, an ultrasonic extraction method, a supercritical extraction method, a subcritical extraction method, a solvent extraction method, an elution method, a squeezing method, a high temperature extraction method, a high pressure extraction method, an extraction method using an adsorption resin including XAD and HP-20, or a fermentation or natural fermentation metabolism using a microorganism, in consideration of the degree of extraction or the degree of preservation of an active ingredient. The number of extraction times may be 1 to 5, and after extraction, a method such as distillation under reduced pressure, concentration under reduced pressure, freeze drying or spray drying may additionally be performed.
In an exemplary embodiment, the extract may be one or more solvent extracts selected from the group consisting of water and alcohol.
In an exemplary embodiment, the alcohol may be a C1-C4 alcohol.
In an exemplary embodiment, the alcohol may be one or more selected from the group consisting of methanol, ethanol, butanol, propanol, isopropanol and glycerol.
In an exemplary embodiment, the lipolytic component may be included preferably in an amount of 9 to 12% by weight based on the total weight of the composition.
In an exemplary embodiment, the mixed extract may be included preferably at 0.5 to 3% by weight based on the total weight of the composition.
The composition of the present invention comprises the lipolytic component and the mixed extract in the above-described ranges in order to suppress the dosage form stability, skin safety and the decrease in lipolytic effect, thereby being capable of exhibiting excellent lipolytic effect.
In an exemplary embodiment, the lecithin may be dissolved in an organic solvent, for example, one or more of ethanol and glycerol, and then used.
In an exemplary embodiment, the lipolytic composition may comprise carnitine.
In an exemplary embodiment, the mixed extract may include a plum extract, a honeysuckle extract, a scutellaria root extract and a melissa leaf extract.
In an exemplary embodiment, the mixed extract may include Garcinia cambogia (Garcinia cambogia) extract, puer tea (Camellia Sinensis) extract, and mangifera (Irvingia gabonensis) extract. The composition of the present invention provides a synergistic effect of further improving the lipolytic efficacy of the lipolytic component by comprising a mixed extract of 7 natural products.
In an exemplary embodiment, the mixed extract may include garcinia cambogia extract, puer tea extract and mango seed extract.
In an exemplary embodiment, the composition may comprise propylene carbonate, isoprene glycol, ethanol, PEG-40 hydrogenated castor oil, and purified water.
In an exemplary embodiment, the composition comprises 3 to 7% by weight of propylene carbonate, 1 to 5% by weight of isoprene glycol, 20 to 24% by weight of ethanol, 0.8 to 1.2% by weight of PEG-40 hydrogenated castor oil, and 18 to 23% by weight of purified water, based on the total weight of the composition, so that a liquid composition having excellent formulation stability and lipolytic effect, which contains a lipolytic component and a mixed extract, can be provided.
In an exemplary embodiment, the composition can be a slimming composition.
In an exemplary embodiment, the composition may be a liquid composition. The liquid composition for lipolysis of the present invention is easy to apply and absorb to the skin, thus exhibiting excellent effects of lipolysis, cellulite removal, and lifting, and is not greasy, thus being very convenient to use.
In an exemplary embodiment, the composition may be used to improve and/or remove cellulite.
In an exemplary embodiment, the composition may be a skin external composition. The external skin preparation is a generic term which may include any external preparations to be applied to the outside of the skin, and may include various pharmaceutical preparations. For example, the composition may be in the form of an ointment, lotion, gel, cream, spray, suspension, emulsion, patch, etc., but is not limited thereto.
In an exemplary embodiment, the composition for external skin preparation may further contain, in addition to the active ingredient of the present invention, preservatives, stabilizers, wetting agents or emulsion promoters, auxiliary agents such as salts and/or buffers for adjusting osmotic pressure, and other therapeutically useful substances.
In an exemplary embodiment, the composition may be a cosmetic composition.
The cosmetic composition may further include functional additives and ingredients contained in general cosmetic compositions in addition to the mixed extract. The functional additive may include one or more components selected from the group consisting of water-soluble vitamins, oil-soluble vitamins, polymer peptides, polymer polysaccharides, sphingolipids, and seaweed extracts. Examples of the other ingredients that may be contained include an oil and fat ingredient, a moisturizer, an emollient, a surfactant, an organic and inorganic pigment, an organic powder, a filler, a sequestering agent, a chelating agent, a wetting agent, an ultraviolet absorber, a preservative, a bactericide, an antioxidant, a plant extract, a pH adjuster, an alcohol, a pigment, a perfume, a blood circulation promoter, a cold feeling agent, an antiperspirant, and purified water.
The formulation of the cosmetic composition is not particularly limited and may be appropriately selected according to the purpose. For example, one or more formulations selected from the group consisting of a lotion, a toner, a milky lotion, a moisturizing lotion, a nourishing lotion, a massage cream, a nourishing cream, a moisturizing cream, an essence liquid, a nourishing essence liquid, a mask, a soap, a cleansing foam, a cleansing milk, a cleansing cream, a body milk, a body cleansing milk, an emulsion, a compact, and a loose powder may be prepared, but not limited thereto.
When the formulation of the present invention is a paste, cream or gel, animal fibers, plant fibers, wax, paraffin, starch, tragacanth, cellulose derivatives, polyethylene glycol, silicon, bentonite, silica, talc, zinc oxide, or the like can be used as a carrier component.
When the formulation of the present invention is a powder or a spray, lactose, talc, silica, aluminum hydroxide, calcium silicate or polyamide powder can be used as a carrier component, and particularly when the formulation is a spray, a propellant such as chlorofluorocarbon, propane/butane or dimethyl ether may be further contained.
When the formulation of the present invention is a solution or emulsion, a solvent, a solvating agent or an opacifying agent, for example, water, ethanol, isopropanol, ethyl carbonate, ethyl acetate, benzyl alcohol, benzyl benzoate, propylene glycol, 1, 3-butylene glycol oil, glycerol aliphatic ester, polyethylene glycol or sorbitan fatty acid ester, is used as a carrier component.
When the formulation of the present invention is a suspension, as a carrier component, water, a liquid diluent of ethanol or propylene glycol, a suspending agent such as ethoxylated isostearyl alcohol, polyoxyethylene sorbitol ester, and polyoxyethylene sorbitan ester, microcrystalline cellulose, aluminum metahydroxide (aluminum metahydroxide), bentonite, agar, or tragacanth can be used.
When the formulation of the present invention is a surface-active cleansing milk, fatty alcohol sulfate, fatty alcohol ether sulfate, sulfosuccinic acid monoester, isethionic acid salt, imidazoline derivative, methyl laurate, sarcosinate, fatty acid amide ether sulfate, alkylamide betaine, fatty alcohol, fatty acid glyceride, fatty acid diethanolamide, vegetable oil, lanolin derivative, ethoxylated glycerol fatty acid ester, or the like can be used as the carrier component.
The present invention will be described in more detail with reference to the following examples. These examples are only for illustrating the present invention, and it is apparent to those of ordinary skill in the art that the scope of the present invention is not construed as being limited by these examples.
Experimental example 1
A composition for slimming was produced by a usual method according to the composition shown in table 1 below.
Specifically, ethanol, lecithin and PEG-40 hydrogenated castor oil are heated to 50 ℃ to be dissolved, and mixed with 1, 2-propylene glycol, propylene carbonate and isoprene glycol under stirring, and then sodium deoxycholate is added into an emulsion tank under stirring. Then, purified water, pentanediol, octanediol, adipic acid, a plum fruit extract, a honeysuckle flower extract, a scutellaria root extract, a gamboge fruit extract, carnitine HCL, a puer tea leaf extract, a wild mango seed extract, and a lemon balm leaf extract were mixed, and then put into an emulsifying tank and stirred to manufacture the liquid slimming composition of example 1. The 7 kinds of natural product extracts were extracted with distilled water at 90 to 100 ℃ for 4 hours for 2 times, respectively, and then used after being filtered and concentrated under reduced pressure. The prepared liquid composition for losing weight is very convenient to apply on the skin, is hardly greasy, and does not stick to clothes.
Similarly, the liquid slimming compositions of comparative examples 1 to 3 were prepared according to the compositions of table 1 below and the lipolytic effect was compared.
TABLE 1
Experimental example 2
In order to confirm the lipolytic effect of the compositions of example 1 and comparative examples 1 to 3, the degree of cellulite removal was evaluated and compared as follows.
Selecting BMI (body Mass index, weight (kg)/height (m) from female with cellulite2) 40 adult women of 25-50 years of age 21-27 and randomly divided into 4 groups. In each group of 10, the weight-reducing compositions of example 1 and comparative examples 1 to 3 were applied to one inner thigh of a user while massaging the user twice a day in the morning and at night over a period of 4 weeks.
TABLE 2
| Example 1 | Comparative example 1 | Comparative example 2 | Comparative example 3 | |
| Change in cellulite rating | 1.5 | 0.7 | 0.9 | 1.0 |
Regarding the degree of cellulite, evaluation was performed by calculating an average value of visual evaluation grade scores of 3 professional researchers before and after 4 weeks of use of the composition. The degree of cellulite was evaluated by visual evaluation into 5 grades of 0 to 4 (0: many cellulite to 4: no cellulite), and the average of the absolute values of the values obtained by subtracting the evaluation grade values after use from the evaluation grade values before use of the composition for losing weight is shown in table 2.
As a result, it was confirmed that the composition of example 1 had a statistically significant reduction in cellulite. Even though the compositions of example 1 and comparative examples 1 to 3 both contained the lipolytic component, differences were exhibited in lipolytic effect depending on the extract component used together with the lipolytic component. The cellulite evaluation scale score of the composition of example 1 containing both the lipolytic component and the 7 natural product extracts was greatly increased compared to the compositions of comparative examples 1 to 3, confirming that the 7 natural product extracts showed a synergistic effect in lipolytic effect. In addition, the composition of example 1 exhibited an excellent cellulite removing effect compared to the composition of comparative example 2 containing a green tea extract known to have a lipolytic effect, and thus it was confirmed that the composition of 7 natural product extracts had an excellent effect. From this, it was found that the weight-reducing effect of the composition of the present invention was very prominent.
While certain aspects of the present invention have been described in detail, those skilled in the art will readily appreciate that the detailed description is of the preferred embodiments and that the scope of the present invention is not limited thereto. Accordingly, the actual scope of the invention should be defined by the appended claims and equivalents thereof.
Claims (10)
1. Use of a lipolytic component and a mixed extract for the manufacture of a composition for lipolytic activity,
the lipolytic composition comprises lecithin and sodium deoxycholate; and is
The mixed extract comprises plum extract, honeysuckle extract, scutellaria extract and melissa extract.
2. The use according to claim 1, wherein the lipolytic ingredient is used in an amount of 9 to 12 wt% based on the total weight of the lipolytic composition.
3. The use according to claim 1, wherein the mixed extract is used in an amount of 0.5 to 3% by weight based on the total weight of the composition for lipolysis.
4. The use of claim 1, wherein the mixed extract comprises plum extract, honeysuckle extract, scutellaria root extract and melissa leaf extract.
5. The use of claim 1, wherein the mixed extract comprises garcinia cambogia extract, puer tea extract and mango extract.
6. The use of claim 1, wherein the lipolytic composition and mixed extract are used with propylene carbonate, isoprene glycol, ethanol, PEG-40 hydrogenated castor oil and purified water.
7. The use of claim 6, wherein the propylene carbonate, isoprene glycol, ethanol, PEG-40 hydrogenated castor oil and purified water are used in an amount of 3 to 7 wt% of propylene carbonate, 1 to 5 wt% of isoprene glycol, 20 to 24 wt% of ethanol, 0.8 to 1.2 wt% of PEG-40 hydrogenated castor oil and 18 to 23 wt% of purified water, based on the total weight of the composition for lipolysis.
8. The use according to claim 1, wherein the lipolytic composition is a slimming composition.
9. Use according to claim 1, wherein the lipolytic composition is a liquid composition.
10. The use according to claim 1, wherein the composition for lipolysis is a cosmetic composition.
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|---|---|---|---|
| CN202010530714.9A CN113797259A (en) | 2020-06-11 | 2020-06-11 | Composition for lipolysis |
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| CN202010530714.9A CN113797259A (en) | 2020-06-11 | 2020-06-11 | Composition for lipolysis |
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| KR20140133721A (en) * | 2013-05-10 | 2014-11-20 | 주식회사 아미팜 | Composition comprising phosphatidylcholine for lipolysis and manufacturing method thereof |
| CA2872279A1 (en) * | 2014-11-21 | 2016-05-21 | Pankaj Modi | Topical lipolysis compositions and methods |
| CN107865964A (en) * | 2016-09-22 | 2018-04-03 | 李京洛 | Hypo-osmoticity lipolysis composition and preparation method thereof |
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2020
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| CN102283386A (en) * | 2011-08-16 | 2011-12-21 | 中国林业科学研究院亚热带林业研究所 | Composite camellia oil health care product with function of reducing blood fat and preparation method thereof |
| KR20140133721A (en) * | 2013-05-10 | 2014-11-20 | 주식회사 아미팜 | Composition comprising phosphatidylcholine for lipolysis and manufacturing method thereof |
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| 黄振国，等: "乌龙强力减肥茶减肥作用实验研究", 《福建中医药》 * |
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Application publication date: 20211217 |