CN113730953B - Supercritical extract total mixing device for preparing gouty arthritis arthralgia tablet - Google Patents

Supercritical extract total mixing device for preparing gouty arthritis arthralgia tablet Download PDF

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Publication number
CN113730953B
CN113730953B CN202111041572.0A CN202111041572A CN113730953B CN 113730953 B CN113730953 B CN 113730953B CN 202111041572 A CN202111041572 A CN 202111041572A CN 113730953 B CN113730953 B CN 113730953B
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shell
opening
transmission mechanism
pump body
communicated
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CN113730953A (en
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夏伟
赵勇
赵栋磊
张楠
张涛
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HEFEI JINYUE PHARMACEUTICAL CO Ltd
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HEFEI JINYUE PHARMACEUTICAL CO Ltd
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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D11/00Solvent extraction
    • B01D11/02Solvent extraction of solids
    • B01D11/0203Solvent extraction of solids with a supercritical fluid
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D11/00Solvent extraction
    • B01D11/02Solvent extraction of solids
    • B01D11/0288Applications, solvents

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  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
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Abstract

The invention discloses a supercritical extract total mixing device for preparing gouty arthritis arthralgia tablets, which relates to the technical field of traditional Chinese medicine recovery equipment and comprises a shell, wherein two crushing rods are arranged in the shell in parallel and connected through a gear set, one of the crushing rods is connected with a speed reducing motor arranged on the shell: the inner wall of the shell is provided with at least two openings for communicating the inside and the outside of the shell; install the pump body on the casing, the play liquid end of the pump body is always open, the feed liquor end intercommunication of the pump body has the pipeline, the one end intercommunication that the pump body was kept away from to the pipeline has the shunt tubes that quantity and opening are the same, and shunt tubes and opening intercommunication. According to the invention, the channels and the alternative opening and closing mechanisms matched with the channels are arranged, so that two adjacent openings are alternately communicated with the flow dividing pipe through the channels, and thus, local hydraulic pressure can be increased through rapid high-frequency replacement, and the liquid pumping area and the liquid pumping pressure are taken into consideration.

Description

Supercritical extract total mixing device for preparation of gouty arthritis arthralgia tablet
Technical Field
The invention relates to the technical field of traditional Chinese medicine recovery equipment, in particular to a supercritical extract total mixing device for preparing gouty arthritis arthralgia tablet.
Background
Arthralgia syndrome refers to a syndrome caused by wind, cold, dampness, heat and the like, mainly manifested by soreness, numbness, heaviness, difficulty in flexion and extension of joints and even swelling and burning of joints, and has a wide concept including visceral arthralgia and limb arthralgia, and arthralgia of limbs including rheumatic fever (rheumatic arthritis), rheumatoid arthritis, osteoarthritis and the like in western medicine. The BIKE tablet is prepared with Chinese medicinal materials of Yunobi plateau, chinese medicinal materials including white astringing, wufeng, sarcandra, orientvine, etc. and through modern biotechnology and pharmaceutical process. Can be used for treating muscle and joint pain caused by arthralgia due to dampness and heat, and rheumatoid arthritis.
The important extraction of the Binke tablet in the prior art usually adopts the technologies of ultrasonic extraction, enzyme extraction, flash extraction, ultrafiltration extraction, supercritical fluid extraction and the like.
The supercritical fluid extraction technology is mainly applied to extraction and separation of effective components of traditional Chinese medicines, has the advantages of no damage to thermosensitive components, simple and convenient operation, wide application range, high efficiency and the like, and is particularly widely applied to volatile oil extraction and separation research. However, the supercritical fluid extraction technology is mainly used for laboratory research at present, but is relatively weak in industrialization, lacks a complete mixing device before extraction of an extract, cannot be used in large-scale industrial production, and particularly has a problem of how to simultaneously collect extruded liquid and dust of traditional Chinese medicines when the extract is crushed and mixed before extraction, so that the change is urgently needed.
Disclosure of Invention
The invention aims to solve the problems and provides a supercritical extract total mixing device for preparing gouty arthritis arthralgia tablet.
In order to achieve the purpose, the invention adopts the following technical scheme:
the supercritical extract total mixing device for preparing the gouty arthritis bike tablet comprises a shell, wherein two crushing rods are arranged in the shell in parallel, the two crushing rods are connected through a gear set, and one of the crushing rods is connected with a speed reduction motor arranged on the shell;
the inner wall of the shell is provided with at least two openings for communicating the inside and the outside of the shell;
install the pump body on the casing, the play liquid end of the pump body is always on, the feed liquor end intercommunication of the pump body has the pipeline, the one end intercommunication that the pump body was kept away from to the pipeline has the shunt tubes that quantity and opening are the same, and shunt tubes and opening intercommunication.
Optionally, the number of the openings is an even number, two adjacent openings are defined as a group, the openings and the division pipe 7 are communicated through a channel, the channel is communicated with the division pipe, a normally open liquid suction port is formed in the casing, and the normally open liquid suction port is communicated with the pipeline.
Optionally, two openings in the same group are provided with an alternative opening and closing mechanism together, and the alternative opening and closing mechanism is used for alternately communicating the two openings in the same group with the channel.
Optionally, the alternating opening and closing mechanism comprises a first connecting rod, a second connecting rod and a piston;
the bottom of piston is seted up the T die cavity with outside intercommunication, the quantity of first connecting rod is two, and the one end that the two is close to each other is V font coaxial coupling, and the two one end of keeping away from each other rotates with the second connecting rod respectively to be connected, second connecting rod and piston fixed connection, the piston is located the opening and just with the opening separation.
Optionally, the alternate opening and closing mechanism further comprises a limiting assembly, and the limiting assembly is composed of a polished rod, a bracket and a sliding block;
the sliding block is fixedly connected with the piston, the polished rod is in sliding connection with the sliding block, and the polished rod is vertically fixed on the shell through the support.
Optionally, a second transmission mechanism is arranged on the outer side of the casing, the second transmission mechanism has an input end and an output end, the output end of the second transmission mechanism is connected with the alternate opening and closing mechanism and drives the alternate opening and closing mechanism to move, and the input end of the second transmission mechanism is connected with the gear set through the first transmission mechanism.
Optionally, the second transmission mechanism comprises a ball screw, a ball nut and a slide rod;
the ball screw is in threaded connection with the ball nut, the ball nut is rotatably connected to the shell, the ball screw is fixedly connected with the sliding rod, the sliding rod is connected to the shell in a sliding mode, and one end, far away from the second connecting rod, of the first connecting rod is connected to the sliding rod in a shaft mode.
Optionally, the first transmission mechanism includes belt drive mechanism, driven gear and incomplete gear, the quantity of incomplete gear is two and the symmetry sets up two at driven gear, two incomplete gear has and only one simultaneously and driven gear meshing, two connect through belt drive mechanism between the incomplete gear, one of them incomplete gear and a coaxial setting of gear in the gear train, driven gear and ball nut's external surface key-type connection.
The invention has the following advantages:
according to the invention, the channels and the alternate opening and closing mechanisms matched with the channels are arranged, so that two adjacent openings are alternately communicated with the flow dividing pipe through the channels, and thus, local hydraulic pressure can be increased through rapid high-frequency replacement, so that the liquid extracting area and the liquid extracting pressure are taken into consideration, and meanwhile, dust can be synchronously collected.
According to the invention, the first transmission mechanism and the second transmission mechanism are arranged, the incomplete gear meshed with the incomplete gear is driven to rotate by the power of the gear set, the two incomplete gears are connected through the belt transmission mechanism, so that the two incomplete gears are alternately meshed with the driven gear, and finally, the reciprocating rotation of the ball nut is realized, the ball nut is driven to reciprocate by the reciprocating drive of the first transmission mechanism, so that the reciprocating motion of the ball screw is finally realized, the ball screw can drive the slide rod to reciprocate during reciprocating motion, and therefore, the alternate opening and closing mechanism can be driven to move, and the alternate opening and closing mechanism is provided with the power of alternate motion.
Drawings
FIG. 1 is a schematic view of a shredder bar according to the present invention;
FIG. 2 is a schematic view of the conduit and shunt tube of the present invention;
FIG. 3 is a top plan view of the integral decapper of the present invention;
FIG. 4 is an overall exterior top view of the present invention;
FIG. 5 is a schematic view of a first transmission mechanism according to the present invention;
FIG. 6 is a side view of a first drive mechanism of the present invention;
FIG. 7 is a schematic view of a second transmission mechanism of the present invention;
FIG. 8 is a schematic view of an alternate opening and closing mechanism of the present invention;
fig. 9 is a schematic view of the middle stop assembly of the present invention.
In the figure: 1 shell, 2 crushing rods, 3 reduction motors, 4 gear sets, 5 pump bodies, 6 pipelines, 7 shunt tubes, 8 openings, 9 normally open liquid suction ports, 10 channels, 11 first transmission mechanisms, 111 incomplete gears, 112 driven gears, 113 belt transmission mechanisms, 12 second transmission mechanisms, 121 ball screws, 122 ball nuts, 123 couplers, 124 sliding rods, 125 sliding strips, 126 stops, 13 alternate opening and closing mechanisms, 131 first connecting rods, 132 second connecting rods, 133 pistons, 134T cavities 134, 135 limiting assemblies, 1351 polished rods, 1352 supports and 1353 sliding blocks.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the drawings in the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments.
Example one
Referring to fig. 1 and 2, two crushing rods 2 are arranged in parallel in the housing 1, two the crushing rods 2 are connected through a gear set 4, the gear set 4 is composed of two gears, the two gears are respectively connected with the crushing rods 2 through coaxial keys, and the two gears are located on the outer side of the housing 1, so that the influence on the crushing rods 2 is avoided.
One of the crushing rods 2 is connected with a speed reducing motor 3 installed on the shell 1, and the speed reducing motor 3 can adopt a common worm gear speed reducing motor, a common planet gear speed reducing motor and the like on the market.
The inner wall of the shell 1 is provided with at least two openings 8 for communicating the inside and the outside of the shell 1, and the openings 8 can be rectangular, triangular, circular and the like and are used for communicating the inside and the outside of the shell 1.
Install the pump body 5 on the casing 1, the play liquid end of the pump body 5 is always on, the feed liquor end intercommunication of the pump body 5 has pipeline 6, the one end intercommunication that the pump body 5 was kept away from to pipeline 6 has the shunt tubes 7 that quantity and opening 8 are the same, and shunt tubes 7 and opening 8 intercommunication.
When traditional chinese medicine is retrieved shredding, start pump body 5, pump body 5 carries out the drawing liquid to can take out liquid through opening 8, shunt tubes 7, pipeline 6, opening 8's quantity should be as much as possible, and evenly distributed at the surface of casing 1, thereby realize comprehensive, even drawing liquid operation.
Example two
Referring to fig. 2, in this embodiment, on the basis of the first embodiment, a channel 10 and a normally open liquid suction port 9 are further disposed between the opening 8 and the shunt tube 7, specifically as follows:
the number of the openings 8 is even, and two adjacent openings 8 are defined as a group and are communicated with each other through a channel 10, and the channel 10 is communicated with the shunt tubes 7. By the provision of the channel 10, it is possible to achieve an alternating communication of the subsequent openings 8 with the channel 10.
The shell 1 is provided with a normally open liquid suction port 9, the normally open liquid suction port 9 is communicated with the pipeline 6, the normally open liquid suction port 9 is arranged at the feed inlet of the shell 1, and the feed inlet is always communicated with the outside, so that the liquid at the feed inlet is normally sucked, and the liquid is prevented from splashing from the feed inlet to the maximum extent.
EXAMPLE III
On the basis of the second embodiment, the alternate opening and closing mechanism 13, the second transmission mechanism 12 and the first transmission mechanism 11 which are used in cooperation with the channel 10 are further arranged, so that the two adjacent openings 8 are communicated with the shunt tubes 7 through the channel 10 alternately, local hydraulic pressure can be increased through rapid high-frequency replacement, and the liquid pumping area and the liquid pumping pressure are considered.
Referring to fig. 5 and 6, the first transmission mechanism 11 includes a belt transmission mechanism 113, a driven gear 112 and incomplete gears 111, the number of the incomplete gears 111 is two, and the incomplete gears 111 are symmetrically arranged on two of the driven gears 112, one and only one of the two incomplete gears 111 is engaged with the driven gear 112, the two incomplete gears 111 are connected through the belt transmission mechanism 113, one of the incomplete gears 111 is coaxially arranged with one of the gears in the gear set 4, and the driven gear 112 is keyed with the outer surface of the ball nut 122.
The first transmission 111 should also include a housing to shield all components therein.
The principle of the first transmission 111 is as follows: the incomplete gear 11 meshed with the gear set 4 is driven to rotate by the power of the gear set 4, and the two incomplete gears 11 are connected through the belt transmission mechanism 113, so that the two incomplete gears 11 are alternately meshed with the driven gear 112, and finally, the reciprocating rotation of the ball nut 112 is realized.
The outer side of the shell 1 is provided with a second transmission mechanism 12, the second transmission mechanism 12 is provided with an input end and an output end, the output end of the second transmission mechanism 12 is connected with an alternate opening and closing mechanism 13 and drives the alternate opening and closing mechanism to move, and the input end of the second transmission mechanism 12 is connected with the gear set 4 through a first transmission mechanism 11.
Referring to fig. 7, the second transmission mechanism 12 includes a ball screw 121, a ball nut 122, and a slide rod 124. The method comprises the following specific steps:
the ball screw 121 is in threaded connection with the ball nut 122, the ball nut 122 is rotatably connected to the housing 1, the ball screw 121 is fixedly connected with the slide rod 124, the slide rod 124 is slidably connected to the housing 1, and one end of the first connecting rod 131, which is far away from the second connecting rod 132, is connected to the slide rod 124 through a shaft.
In this embodiment, the ball screw 121 is fixedly connected to the sliding rod 124 through a coupling, which is easy to install and disassemble.
In this embodiment, the sliding rod 124 is slidably connected with a sliding sleeve 125, the sliding sleeve 125 is fixedly connected with the housing 1, and the sliding sleeve 124 may specifically adopt a linear bearing, so as to improve the mechanical movement efficiency.
In this embodiment, a stop 126 is disposed at an end of the ball screw 121 and the sliding rod 124 away from each other, so as to prevent the ball screw 121 or the sliding rod 124 from being disengaged.
The principle of the second transmission mechanism 12 is as follows: the ball nut 112 is driven by the first transmission mechanism 11 to reciprocate, so as to finally realize the reciprocating motion of the ball screw 121, and the ball screw 121 drives the slide rod 124 to reciprocate when reciprocating.
Referring to fig. 8, two openings 8 in the same group are commonly provided with an alternate opening and closing mechanism 13, and the alternate opening and closing mechanism 13 is used for alternately communicating the two openings 8 in the same group with the channel 10. The alternate opening and closing mechanism 13 includes a first connecting rod 131, a second connecting rod 132, and a piston 133, and the specific details are as follows:
the bottom end of the piston 133 is provided with a T-shaped cavity 134 communicated with the outside, the number of the first connecting rods 131 is two, the two ends close to each other are coaxially connected in a V-shape, the two ends far away from each other are rotatably connected with the second connecting rod 132 respectively, the second connecting rod 132 is fixedly connected with the piston 133, and the piston 133 is located in the opening 8 and blocks the opening 8.
The principle of the alternate opening and closing mechanism 13 is as follows: because two adjacent first connecting rods 131 are coaxially connected in a V-shape, the two first connecting rods will alternately drive the second connecting rod 132 to reciprocate under the driving of the sliding rod 124, so as to finally drive the piston 133 to reciprocate, thereby realizing that the T-shaped cavity 134 on the piston 133 is alternately communicated with the channel 10.
The alternate opening and closing mechanism 13 further comprises a limiting assembly 135, the limiting assembly 135 is composed of a polished rod 1351, a support 1352 and a sliding block 1353, the piston 133 can only move linearly up and down due to the limiting assembly 135, and the stability is improved, specifically as follows:
the sliding block 1353 is fixedly connected with the piston 133, the polish rod 1351 is slidably connected with the sliding block 1353, and the polish rod 1351 is vertically fixed on the housing 1 through a bracket 1352.
While the invention has been described with reference to specific embodiments, it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention.

Claims (2)

1. A supercritical extract total device that mixes for preparation of gouty arthritis beck piece, including casing (1), parallel arrangement has two crushing poles (2) in casing (1), two connect through gear train (4) between crushing pole (2), one of them crushing pole (2) are connected with gear motor (3) of installing on casing (1), its characterized in that:
the inner wall of the shell (1) is provided with at least two openings (8) for communicating the inside and the outside of the shell (1);
the pump body (5) is installed on the shell (1), the liquid outlet end of the pump body (5) is normally open, the liquid inlet end of the pump body (5) is communicated with a pipeline (6), one end, far away from the pump body (5), of the pipeline (6) is communicated with shunt tubes (7) with the same number as the opening (8), and the shunt tubes (7) are communicated with the opening (8);
the number of the openings (8) is even, two adjacent openings (8) are defined as a group and are communicated with each other through a channel (10), the channel (10) is communicated with the shunt pipe (7), a normally open liquid suction port (9) is formed in the shell (1), and the normally open liquid suction port (9) is communicated with the pipeline (6); the two openings (8) in the same group are jointly provided with an alternative opening and closing mechanism (13), and the alternative opening and closing mechanism (13) is used for alternately communicating the two openings (8) in the same group with the channel (10);
the alternate opening and closing mechanism (13) comprises a first connecting rod (131), a second connecting rod (132) and a piston (133), a T-shaped cavity (134) communicated with the outside is formed in the bottom end of the piston (133), the number of the first connecting rods (131) is two, the ends, close to each other, of the first connecting rods (131) are coaxially connected in a V shape, the ends, far away from each other, of the first connecting rods (131) are rotatably connected with the second connecting rod (132) respectively, the second connecting rod (132) is fixedly connected with the piston (133), and the piston (133) is located in the opening (8) and blocks the opening (8);
a second transmission mechanism (12) is arranged on the outer side of the shell (1), the second transmission mechanism (12) is provided with an input end and an output end, the output end of the second transmission mechanism (12) is connected with the alternate opening and closing mechanism (13) and drives the alternate opening and closing mechanism to move, and the input end of the second transmission mechanism (12) is connected with the gear set (4) through the first transmission mechanism (11);
the first transmission mechanism (11) comprises a belt transmission mechanism (113), two driven gears (112) and incomplete gears (111), the number of the incomplete gears (111) is two, the incomplete gears are symmetrically arranged on two of the driven gears (112), only one of the two incomplete gears (111) is meshed with the driven gear (112), the two incomplete gears (111) are connected through the belt transmission mechanism (113), one incomplete gear (111) is coaxially arranged with one gear in the gear set (4), and the driven gear (112) is in key connection with the outer surface of a ball nut (122);
the second transmission mechanism (12) comprises a ball screw (121), a ball nut (122) and a sliding rod (124); the ball screw (121) is in threaded connection with the ball nut (122), the ball nut (122) is rotatably connected to the shell (1), the ball screw (121) is fixedly connected with the sliding rod (124), the sliding rod (124) is slidably connected to the shell (1), and one end, far away from the second connecting rod (132), of the first connecting rod (131) is connected to the sliding rod (124) in a shaft mode.
2. The supercritical extract total mixing apparatus for the preparation of gouty arthritis beck tablet according to claim 1, characterized in that the alternating open and close mechanism (13) further comprises a limit component (135), the limit component (135) is composed of a polish rod (1351), a bracket (1352) and a slide block (1353);
the sliding block (1353) is fixedly connected with the piston (133), the polish rod (1351) is slidably connected with the sliding block (1353), and the polish rod (1351) is vertically fixed on the shell (1) through a bracket (1352).
CN202111041572.0A 2021-09-07 2021-09-07 Supercritical extract total mixing device for preparing gouty arthritis arthralgia tablet Active CN113730953B (en)

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CN202111041572.0A CN113730953B (en) 2021-09-07 2021-09-07 Supercritical extract total mixing device for preparing gouty arthritis arthralgia tablet

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CN113730953B true CN113730953B (en) 2022-11-11

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Citations (6)

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JP2005058149A (en) * 2003-08-19 2005-03-10 Fuji Photo Film Co Ltd Apparatus for extracting nucleic acid
CN1962016A (en) * 2005-11-09 2007-05-16 严晓敏 Modified Soxhlet, split type combined and alternatively multiple circulating extraction method and equipment
CN102587879A (en) * 2012-03-22 2012-07-18 胜利油田泰峰机电有限责任公司 Oil production method using steam power to lift thick oil
CN209060596U (en) * 2018-09-12 2019-07-05 北京康沪中医药研究院 A kind of Chinese medicine distillation extraction kettle
CN110314752A (en) * 2019-08-16 2019-10-11 三门宣教机械设备有限公司 A kind of plant medicine constituents extraction equipment
CN210448171U (en) * 2019-08-06 2020-05-05 周伟芳 Traditional chinese medicine extraction device

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1398189B1 (en) * 2010-02-16 2013-02-14 Cozzolino SURFACE HEAT EXCHANGER FOR VOLUMETRIC MACHINES WITH COMPRESSIBLE FLUID.
CN102886078A (en) * 2011-07-19 2013-01-23 捷锐企业(上海)有限公司 Timing unit for intermittent vacuum regulator
CA2995169C (en) * 2015-07-17 2020-10-27 Enrique Maya Nates Organic material processing system

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005058149A (en) * 2003-08-19 2005-03-10 Fuji Photo Film Co Ltd Apparatus for extracting nucleic acid
CN1962016A (en) * 2005-11-09 2007-05-16 严晓敏 Modified Soxhlet, split type combined and alternatively multiple circulating extraction method and equipment
CN102587879A (en) * 2012-03-22 2012-07-18 胜利油田泰峰机电有限责任公司 Oil production method using steam power to lift thick oil
CN209060596U (en) * 2018-09-12 2019-07-05 北京康沪中医药研究院 A kind of Chinese medicine distillation extraction kettle
CN210448171U (en) * 2019-08-06 2020-05-05 周伟芳 Traditional chinese medicine extraction device
CN110314752A (en) * 2019-08-16 2019-10-11 三门宣教机械设备有限公司 A kind of plant medicine constituents extraction equipment

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Denomination of invention: Supercritical extraction total mixing device for the preparation of gouty arthritis Bike tablets

Effective date of registration: 20240103

Granted publication date: 20221111

Pledgee: Huishang Bank Co.,Ltd. Hefei Economic Development Zone sub branch

Pledgor: HEFEI JINYUE PHARMACEUTICAL Co.,Ltd.

Registration number: Y2024980000208

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