CN113730485A - Acne-removing traditional Chinese medicine ointment and preparation method thereof - Google Patents

Acne-removing traditional Chinese medicine ointment and preparation method thereof Download PDF

Info

Publication number
CN113730485A
CN113730485A CN202110653309.0A CN202110653309A CN113730485A CN 113730485 A CN113730485 A CN 113730485A CN 202110653309 A CN202110653309 A CN 202110653309A CN 113730485 A CN113730485 A CN 113730485A
Authority
CN
China
Prior art keywords
acne
chinese medicine
traditional chinese
preparation
matrix
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN202110653309.0A
Other languages
Chinese (zh)
Inventor
张洪琼
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN202110653309.0A priority Critical patent/CN113730485A/en
Publication of CN113730485A publication Critical patent/CN113730485A/en
Pending legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/85Verbenaceae (Verbena family)
    • A61K36/855Clerodendrum, e.g. glorybower
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/19Acanthaceae (Acanthus family)
    • A61K36/195Strobilanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/287Chrysanthemum, e.g. daisy
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • A61K36/315Isatis, e.g. Dyer's woad
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/536Prunella or Brunella (selfheal)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/739Sanguisorba (burnet)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/752Citrus, e.g. lime, orange or lemon
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/82Theaceae (Tea family), e.g. camellia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/86Violaceae (Violet family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02Inorganic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12Carboxylic acids; Salts or anhydrides thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/20Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing sulfur, e.g. dimethyl sulfoxide [DMSO], docusate, sodium lauryl sulfate or aminosulfonic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/10Anti-acne agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Zoology (AREA)
  • Inorganic Chemistry (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Pain & Pain Management (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Cosmetics (AREA)

Abstract

The invention discloses acne-removing traditional Chinese medicine ointment and a preparation method thereof, and the acne-removing traditional Chinese medicine ointment comprises traditional Chinese medicine raw materials and a mixed matrix, wherein the traditional Chinese medicine raw materials comprise 10g of folium isatidis, 12g of dandelion, 10g of wild chrysanthemum flower, 10g of green tea leaves, 15g of selfheal, 10g of honeysuckle, 15g of pansy, 12g of purslane, 10g of pearl powder, 15g of garden burnet, 15g of liquorice, 15g of fructus forsythiae, 12g of orange peel and 15g of dictamnus alba, and the mixed matrix comprises a water-phase matrix and an oil-phase matrix.

Description

Acne-removing traditional Chinese medicine ointment and preparation method thereof
Technical Field
The invention relates to the field of acne-removing ointment processing, and particularly relates to acne-removing traditional Chinese medicine ointment and a preparation method thereof.
Background
Acne, commonly known as whelk, is a common problem skin. Acne is easy to occur in the adolescence, most teenagers and girls live in different degrees, the acne is common all the year round, particularly serious in summer, and can be self-healed by people and not healed by people for many years, so that acne pits, acne scars and acne marks are left on the facial skin. From 1985 to 2021, pox and pox crowds are rapidly increased year by year, and are frequently seen in teenagers, young people and middle-aged people, the population in the country is as high as billions, and the number of problematic skins reaches as many as ten million people. Pox is mainly divided into: (1) cyst and pustular acne are well developed around the face, swelling of the pox is accompanied by mauve, the pox is red and hard, the epidermis of the hard is slowly thinned and broken along with the lapse of time, flushing erosion is shown, pus blood liquid can seep out by lightly touching the pox, nausea can be felt when people see the pox, and some cyst and pustular pox are not treated in time and form uneven purple induration; (2) acne and nodular acne marks, wherein the acne is better developed on the whole face, the acne is accompanied by flushing and is red and small red rash at the initial stage, the small white pus heads can emerge over time and are scattered or densely distributed, adjacent rash can be fused into one piece to form a larger area, and the acne can form red pit marks without being treated in time, so the red pit marks are converted into nodular acne marks; (3) sensitive and hormonal acnes belong to artificial acnes, various problems occur on the face due to personal factors, the face is itchy and flushed at the beginning and is accompanied by white rashes, the skin can be seriously burnt, the formed area is different, the face is injured, some acnes are red and black, some acnes are rough like blocks, the sensitive and hormonal acnes are not treated in time, the consequence is serious compared with any acnes, and the sensitive and hormonal acnes are the most difficult problem to solve in the problematic skin and easily and repeatedly appear on the face to bring pain to people.
The existing acne removing cream is mostly a western medicine formula, salicylic acid is used in a large amount, the irritation is strong, the horny layer of the skin is damaged, a user needs to distinguish the characteristics of sensitive muscles to select the acne removing cream, the acne removing cream is troublesome, the traditional Chinese medicine cream formula on the market is mild, the effect is slow, the component exerting function is insufficient, the texture is thick, the texture is greasy when the acne removing cream is used, and the comfortable feeling is poor when the acne removing cream is used in summer with a lot of acnes.
Disclosure of Invention
Aiming at the technical problems, the invention provides an acne-removing traditional Chinese medicine ointment and a preparation method thereof.
The method comprises the following steps:
the preparation method comprises the steps of grinding the medicinal materials, preparing the medicinal materials and condensing the medicinal materials into paste, grinding the medicinal materials, putting the raw Chinese medicinal materials into a grinder according to a formula proportion for mixing and grinding, continuously sieving the raw Chinese medicinal materials during grinding, decocting the sieved raw Chinese medicinal materials, wherein the decoction water is sterile liquid, and the raw Chinese medicinal materials are subjected to ultrasonic mixing and oscillation before decoction, are decocted fully and uniformly and then decocted, and are sieved again after decoction to obtain a Chinese medicinal decoction; secondly, preparing a matrix, namely heating the oil phase matrix to 80 ℃ for melting, filtering by using an eighth sieve, filtering impurities, heating the oil phase matrix to 150 ℃ after removing the impurities, keeping the temperature of 150 ℃ for 1 hour for sterilization and dehydration, heating the water phase matrix to 80 ℃ to 90 ℃, and slowly adding the decocted liquid and the water phase matrix into the oil phase matrix to prepare an emulsion matrix; and thirdly, condensing to form paste, cooling the emulsion matrix in a water-proof way, continuously stirring, condensing and stirring the emulsion matrix to form the paste.
Preferably, the sterile liquid is sterile water.
Preferably, the sterile liquid is a mixed matrix.
Preferably, the mesh number during grinding is six, and the mesh number after decocting and sieving again is eight.
Preferably, the aqueous phase matrix comprises borax, sodium hydroxide, triethanolamine, sodium lauryl sulfate, a humectant and a preservative.
Preferably, the oil phase matrix comprises stearic acid and glyceryl monostearate.
Preferably, the eighth sieve keeps the temperature of the oil phase matrix not lower than 70 ℃ when filtering the oil phase matrix.
Has the advantages that:
1. the paste is prepared by adopting an emulsifying and condensing processing mode, and meanwhile, the mixed matrix is adopted when the traditional Chinese medicine raw materials are decocted, so that the finished paste is lighter and thinner in texture and is easy to wipe.
2. The mode of water-proof cooling is adopted to replace the mode of natural cooling, so that the condensing speed is higher, cold air in low-temperature condensation is reduced from entering the paste, and the distribution of active ingredients of a finished product is more uniform.
3. By adopting the ultrasonic oscillation mode, the components are mixed more fully, the residue after decoction is effectively reduced, less important raw materials are required to be used under the same yield, and the economic benefit is better.
4. The formula with better acne removing effect is adopted, the penetration effect is better, and the acne removing function has the functions of diminishing inflammation and shrinking pores.
Detailed Description
The invention provides an acne-removing traditional Chinese medicine ointment and a preparation method thereof, the acne-removing traditional Chinese medicine ointment comprises traditional Chinese medicine raw materials and mixed matrixes, the traditional Chinese medicine raw materials comprise 10g of folium isatidis, 12g of dandelion, 10g of wild chrysanthemum flower, 10g of green tea leaves, 15g of selfheal, 10g of honeysuckle, 15g of pansy, 12g of purslane, 10g of pearl powder, 15g of garden burnet, 15g of liquorice, 15g of fructus forsythiae, 12g of orange peel and 15g of dictamnus, the mixed matrixes comprise a water phase matrix and an oil phase matrix, the preparation method comprises grinding of medicinal materials, preparation of the matrixes and condensation into the ointment, firstly, grinding of the medicinal materials, putting the traditional Chinese medicine raw materials into a grinder to be mixed and ground according to a formula proportion, continuously sieving in the grinding process, decocting the sieved traditional Chinese medicine raw materials, taking decoction as sterile liquid, mixing and oscillating by ultrasonic waves before decocting, decocting uniformly and then sieving again after decocting, obtaining a traditional Chinese medicine decoction; secondly, preparing a matrix, namely heating the oil phase matrix to 80 ℃ for melting, filtering by using an eighth sieve, filtering to remove impurities, heating the oil phase matrix to 150 ℃, keeping the temperature of 150 ℃ for 1 hour for sterilization and dehydration, heating the water phase matrix to 80 ℃ to 90 ℃, and slowly adding decoction and the water phase matrix into the oil phase matrix to prepare an emulsion matrix; and thirdly, condensing to form paste, cooling the emulsion matrix in a water-proof way, continuously stirring, condensing and stirring the emulsion matrix to form the paste. The sterile liquid is sterile water or a mixed matrix.
The sieving mesh in the grinding process is a No. six sieve, the sieving mesh after decocting is a No. eight sieve, and the water phase matrix comprises borax, sodium hydroxide, triethanolamine, sodium lauryl sulfate, humectant and antiseptic. The oil phase matrix comprises stearic acid and glyceryl monostearate, and the eighth sieve keeps the temperature of the oil phase matrix not lower than 70 ℃ when filtering the oil phase matrix.
The invention adopts the processing mode of emulsification and condensation to prepare the paste, and simultaneously adopts the mixed matrix when decocting the raw materials of the traditional Chinese medicine, so that the finished paste is lighter and thinner in texture and easy to smear. The mode of water proof cooling replaces the mode of natural cooling, and the condensing speed is faster, has reduced cold gas entering lotion in the low temperature condensation, and finished product active ingredient distributes more evenly, adopts the mode of ultrasonic wave vibration, and the composition mixes more fully, and the residue after frying effectively reduces, and the important former material that needs to use is still less under the equal output, and economic benefits is better. The formula with better acne removing effect is adopted, the penetrating effect is better, the acne removing function is achieved while inflammation diminishing and pore shrinking functions are achieved, the folium isatidis has various sterilization effects, the dandelion has the antibacterial and inflammation diminishing effects, and the wild chrysanthemum has the antibacterial and sterilization effects and the effect of preventing pigmentation after acne removing. The green tea has skin whitening, antiaging, antioxidant, and antibacterial effects. Prunellae Spica has effects of removing cyst and pox. Honeysuckle has the functions of strongly permeating pores to sterilize and discharge grease, pansy has the functions of sterilizing, diminishing inflammation, removing acne, resisting allergy and reducing marks, portulaca oleracea has the functions of stopping bleeding and preventing bacterial regeneration, pearl powder has the functions of beautifying, whitening and repairing pale pigments, and sanguisorba has the functions of permeating hair follicles, strongly sterilizing, reducing swelling, astringing wounds and shrinking large and fine skin pores. The liquorice has the effects of diminishing inflammation, repairing cyst and rash, the forsythia has the effects of resisting bacteria, resisting inflammation, promoting permeability of capillary blood, reducing greasiness of skin and repairing skin barriers, the orange peel has the effects of resisting bacteria, diminishing inflammation, fading color and whitening, and the dictamnus has the effects of diminishing swelling and expelling pus.
Various modifications to these embodiments will be readily apparent to those skilled in the art, and the generic principles defined herein may be applied to other embodiments without departing from the spirit or scope of the invention.

Claims (7)

1. An acne-removing traditional Chinese medicine ointment and a preparation method thereof are characterized in that: the preparation method comprises the steps of grinding the medicinal materials, preparing the medicinal materials and condensing the medicinal materials into paste, grinding the medicinal materials, putting the raw Chinese medicinal materials into a grinder according to a formula proportion for mixing and grinding, continuously sieving the raw Chinese medicinal materials in the grinding process, decocting the sieved raw Chinese medicinal materials, wherein the decoction water is sterile liquid, and the raw Chinese medicinal materials are subjected to ultrasonic mixing and oscillation before decoction, are decocted fully and uniformly and then are sieved again, so that a Chinese medicinal decoction is obtained; secondly, preparing a matrix, namely heating the oil phase matrix to 80 ℃ for melting, filtering by using an eighth sieve, filtering to remove impurities, heating the oil phase matrix to 150 ℃, keeping the temperature of 150 ℃ for 1 hour for sterilization and dehydration, heating the water phase matrix to 80 ℃ to 90 ℃, and slowly adding the decoction and the water phase matrix into the oil phase matrix to prepare an emulsion matrix; and thirdly, condensing to form paste, cooling the emulsion matrix in a water-proof way, continuously stirring, condensing and stirring the emulsion matrix to form the paste.
2. The acne-removing traditional Chinese medicine ointment as claimed in claim 1, and the preparation method thereof are characterized in that: the sterile liquid is sterile water.
3. The acne-removing traditional Chinese medicine ointment as claimed in claim 1, and the preparation method thereof are characterized in that: the sterile liquid is a mixed matrix.
4. The acne-removing traditional Chinese medicine ointment as claimed in claim 1, and the preparation method thereof are characterized in that: the mesh number of the sieve in the grinding process is six, and the mesh number of the sieve after decocting is eight.
5. The acne-removing traditional Chinese medicine ointment as claimed in claim 1, and the preparation method thereof are characterized in that: the water phase matrix comprises borax, sodium hydroxide, triethanolamine, sodium lauryl sulfate, humectant and preservative.
6. The acne-removing traditional Chinese medicine ointment as claimed in claim 1, and the preparation method thereof are characterized in that: the oil phase matrix comprises stearic acid and glyceryl monostearate.
7. The acne-removing traditional Chinese medicine ointment as claimed in claim 1, and the preparation method thereof are characterized in that: and when the No. eight sieve filters the oil phase matrix, keeping the temperature of the oil phase matrix not lower than 70 ℃.
CN202110653309.0A 2021-06-11 2021-06-11 Acne-removing traditional Chinese medicine ointment and preparation method thereof Pending CN113730485A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN202110653309.0A CN113730485A (en) 2021-06-11 2021-06-11 Acne-removing traditional Chinese medicine ointment and preparation method thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN202110653309.0A CN113730485A (en) 2021-06-11 2021-06-11 Acne-removing traditional Chinese medicine ointment and preparation method thereof

Publications (1)

Publication Number Publication Date
CN113730485A true CN113730485A (en) 2021-12-03

Family

ID=78728441

Family Applications (1)

Application Number Title Priority Date Filing Date
CN202110653309.0A Pending CN113730485A (en) 2021-06-11 2021-06-11 Acne-removing traditional Chinese medicine ointment and preparation method thereof

Country Status (1)

Country Link
CN (1) CN113730485A (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110279754A (en) * 2019-07-09 2019-09-27 上海市皮肤病医院 A kind of Chinese medicinal granule that treating suppurative dermatosis, preparation method and applications

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110279754A (en) * 2019-07-09 2019-09-27 上海市皮肤病医院 A kind of Chinese medicinal granule that treating suppurative dermatosis, preparation method and applications

Similar Documents

Publication Publication Date Title
CN107007513B (en) External composition with blackhead removing and pore shrinking effects and skin cleaning mask
CN109602686A (en) A kind of aqueous gelled cosmetic compositions and preparation method thereof
CN110368348A (en) A kind of formula of acne removal stock liquid and preparation method thereof
CN100362982C (en) Alopecia-stopping hair-nourishing hair-generating Chinese medicinal shampoo and preparation method thereof
CN108938513B (en) Skin-cleaning acne-removing beauty cream and preparation method thereof
CN107550775B (en) Natural plant anti-acne gel and preparation method thereof
CN115025024B (en) Acne and mark removing composition and application thereof
CN112263495B (en) Plant anti-allergic agent and preparation method and application thereof
KR101238820B1 (en) Soap composition using orient fermentation material and manufacturing method thereof
CN105919863A (en) Acne removing and skin beautifying cream rich in extracts of natural ingredients and preparation method thereof
CN105853297A (en) Oil-control acne-prevention cosmetic containing cedrela sinensis extract and preparing method of oil-control acne-prevention cosmetic
CN108030754A (en) A kind of face cream for eliminating striae of pregnancy and desalinating scar and preparation method thereof
CN104707057B (en) A kind of composition with acne-removing and its preparation method and application
CN112516066B (en) Oil control composition and application thereof in cosmetics
CN105816411A (en) Mask capable of removing acne, whitening skin and achieving nourishing and preparation method of mask
CN102670479B (en) Traditional Chinese medicine antiphlogistic acne-pullout cosmetic cream and preparation method thereof
CN111265642A (en) External medicine for removing nevus, wart and sweat duct tumor and preparation method thereof
CN108938514B (en) Skin-clearing acne-removing liquid and preparation method thereof
CN113730485A (en) Acne-removing traditional Chinese medicine ointment and preparation method thereof
CN109439473B (en) Freckle-removing beauty soap and preparation method thereof
CN108066274A (en) Dark hair compound and its preparation method and application
CN107320417A (en) A kind of century-old grass is dispelled the preparation method of scar composition
CN113855605A (en) Preparation and application method of flower and plant stock solution
CN113476387A (en) Shampoo containing traditional Chinese medicine effective components for nourishing, blackening hair, preventing alopecia and relieving itching and preparation method thereof
CN105687051A (en) Bath salt with acne removal effect and preparation method

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20211203